## Wed Oct 16 10:26:43 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/EH1_bin.50.fa -m mmseqs --itype genome -o EH1_bin.50 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/EH1_bin.50 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
EH1_k127_1023504_0	1163617.SCD_n02184	1.23e-170	544.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH1_k127_1023504_2	243233.MCA2870	3.452e-148	482.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XDNC@135618|Methylococcales	135618|Methylococcales	EH	synthase component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH1_k127_1023504_9	342113.DM82_6012	1.09e-06	51.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VKH2@28216|Betaproteobacteria,1K6NX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
EH1_k127_1023504_8	626887.J057_16215	2.854e-33	137.0	COG0515@1|root,COG2020@1|root,COG0515@2|Bacteria,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
EH1_k127_1023504_6	742823.HMPREF9465_00478	2.979e-62	223.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,2W05P@28216|Betaproteobacteria,4PQYC@995019|Sutterellaceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1023504_4	1163617.SCD_n00464	2.042e-72	258.0	28Q1D@1|root,2ZCJS@2|Bacteria,1RF11@1224|Proteobacteria,2VQZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1023504_7	1288494.EBAPG3_14930	7.691e-56	201.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,2VSUS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
EH1_k127_1023504_5	1123487.KB892846_gene512	1.475e-65	234.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
EH1_k127_1023504_3	292415.Tbd_2538	9.667e-114	374.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2WA3C@28216|Betaproteobacteria,1KRW5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
EH1_k127_1023504_1	1123392.AQWL01000006_gene718	2.947e-165	532.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,1KSJ3@119069|Hydrogenophilales	119069|Hydrogenophilales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1034461_1	1101195.Meth11DRAFT_1775	3.386e-164	522.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KKM4@206350|Nitrosomonadales	206350|Nitrosomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH1_k127_1034461_0	1123360.thalar_02776	8.906e-175	560.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
EH1_k127_1036626_1	935863.AWZR01000001_gene1664	5.485e-25	113.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X52B@135614|Xanthomonadales	135614|Xanthomonadales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
EH1_k127_1036626_0	62928.azo3973	3.003e-105	347.0	COG3179@1|root,COG3409@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	exeA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	-	ko:K02450,ko:K03791,ko:K17733	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko01011,ko02044	9.B.42	GH19	-	AAA_22,Glyco_hydro_19,PG_binding_1
EH1_k127_1050653_1	1163617.SCD_n02937	2.081e-116	378.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
EH1_k127_1050653_2	1121035.AUCH01000005_gene197	1.273e-68	252.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,2KVVZ@206389|Rhodocyclales	206389|Rhodocyclales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
EH1_k127_1050653_3	1123392.AQWL01000002_gene1941	2.302e-64	237.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,1KSN5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_1050653_0	1236959.BAMT01000009_gene3337	2.131e-122	406.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KM7U@206350|Nitrosomonadales	206350|Nitrosomonadales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH1_k127_1054778_4	159087.Daro_2010	2.163e-65	227.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,2KW5K@206389|Rhodocyclales	206389|Rhodocyclales	H	Uroporphyrin-III C tetrapyrrole	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
EH1_k127_1054778_2	640081.Dsui_2466	1.389e-112	371.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase	dnaL	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
EH1_k127_1054778_1	292415.Tbd_0964	1.206e-160	512.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,1KRGN@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH1_k127_1054778_0	580332.Slit_1377	4.905e-216	687.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,44VH2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
EH1_k127_1054778_3	754436.JCM19237_4205	6.799e-87	293.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XUKK@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
EH1_k127_1062138_0	292415.Tbd_0234	1.227e-161	514.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KRGX@119069|Hydrogenophilales	119069|Hydrogenophilales	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
EH1_k127_1062138_1	1115515.EV102420_08_01830	3.171e-93	319.0	COG1397@1|root,COG2453@1|root,COG1397@2|Bacteria,COG2453@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,3XP4M@561|Escherichia	1236|Gammaproteobacteria	O	hydrolase activity	yegU	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
EH1_k127_1068140_1	1123393.KB891329_gene1064	1.036e-55	199.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,2WGQ3@28216|Betaproteobacteria,1KSIT@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
EH1_k127_1068140_2	292415.Tbd_1441	6.428e-43	160.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
EH1_k127_1068140_0	159087.Daro_1296	2.348e-73	252.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
EH1_k127_1068140_3	1236959.BAMT01000001_gene1324	1.118e-15	76.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,2KKKE@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
EH1_k127_1125246_1	1454004.AW11_02872	3.358e-36	137.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,2VJ9U@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K05796	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6,Fer4_9
EH1_k127_1125246_0	748247.AZKH_1616	0.0	1035.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,2KVX2@206389|Rhodocyclales	206389|Rhodocyclales	C	aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
EH1_k127_1125246_2	751994.AGIG01000028_gene1694	3.643e-13	71.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	pyridine nucleotide-disulphide oxidoreductase	hcaD	GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016054,GO:0016999,GO:0017001,GO:0017144,GO:0018962,GO:0019380,GO:0019439,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575	1.18.1.3	ko:K00529,ko:K18227	ko00071,ko00360,ko00622,ko01120,ko01220,map00071,map00360,map00622,map01120,map01220	M00539,M00545	R02000,R05247,R06782,R06783	RC00098,RC00267	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECSP_1301.ECSP_3486,iECs_1301.ECs3408,iSFxv_1172.SFxv_2845,iZ_1308.Z3814	AIF_C,Pyr_redox_2,Reductase_C,Rieske
EH1_k127_1130447_1	1163617.SCD_n01692	6.932e-64	222.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
EH1_k127_1130447_0	1123392.AQWL01000007_gene887	7.967e-131	432.0	COG0664@1|root,COG1295@1|root,COG0664@2|Bacteria,COG1295@2|Bacteria,1PWBZ@1224|Proteobacteria,2VY5Z@28216|Betaproteobacteria,1KSQT@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB,cNMP_binding
EH1_k127_1130539_2	396588.Tgr7_2589	7.611e-204	651.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
EH1_k127_1130539_7	396588.Tgr7_2590	3.799e-20	100.0	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
EH1_k127_1130539_4	396588.Tgr7_2590	2.849e-133	436.0	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
EH1_k127_1130539_1	1123393.KB891317_gene2196	1.088e-256	802.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,1KSF8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP
EH1_k127_1130539_6	1123393.KB891328_gene696	7.079e-97	334.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,1KT8R@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH1_k127_1130539_5	1123393.KB891328_gene695	9.31e-105	344.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,1KTCZ@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH1_k127_1130539_0	522306.CAP2UW1_0121	1.56e-257	824.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
EH1_k127_1130539_3	261292.Nit79A3_3195	1.387e-183	584.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,3745T@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS_4,Response_reg
EH1_k127_1133150_0	1163398.AJJP01000169_gene1153	6.037e-48	197.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
EH1_k127_1151583_0	395494.Galf_2390	5.092e-151	488.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MWDE@1224|Proteobacteria,2WHPR@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1151583_1	522306.CAP2UW1_1904	1.936e-137	460.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
EH1_k127_1151583_3	292415.Tbd_2533	1.33e-49	194.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,1KRSQ@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
EH1_k127_1151583_2	1123392.AQWL01000002_gene2001	6.645e-120	389.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2VURW@28216|Betaproteobacteria,1KSAA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Homoserine O-succinyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTS
EH1_k127_1170524_3	1123393.KB891316_gene2127	7.475e-48	178.0	COG0666@1|root,COG0666@2|Bacteria,1RHTB@1224|Proteobacteria,2WEVK@28216|Betaproteobacteria,1KSWX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
EH1_k127_1170524_2	1122603.ATVI01000006_gene215	6.351e-51	190.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1X71M@135614|Xanthomonadales	135614|Xanthomonadales	PT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
EH1_k127_1170524_0	292415.Tbd_0104	2.602e-294	906.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,1KRXU@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
EH1_k127_1170524_4	640081.Dsui_0249	2.824e-16	88.0	2CJFN@1|root,32ZIB@2|Bacteria,1N7QI@1224|Proteobacteria,2VX2C@28216|Betaproteobacteria,2KX8A@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1170524_1	640081.Dsui_0753	5.493e-247	767.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUDD@206389|Rhodocyclales	206389|Rhodocyclales	S	of ABC transporters with duplicated ATPase	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH1_k127_117387_0	1123393.KB891332_gene2829	1.623e-188	593.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,1KRA6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
EH1_k127_117387_2	1123393.KB891316_gene2076	1.755e-68	247.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,1KSYX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
EH1_k127_117387_1	1123392.AQWL01000006_gene583	1.637e-125	407.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,1KST9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
EH1_k127_117387_3	1101195.Meth11DRAFT_2247	3.305e-13	77.0	COG3767@1|root,COG3767@2|Bacteria,1PW8F@1224|Proteobacteria,2WBTI@28216|Betaproteobacteria,2KN9B@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1178718_8	269799.Gmet_0342	2.861e-62	226.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
EH1_k127_1178718_4	522306.CAP2UW1_0967	1.802e-81	275.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2VV7N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
EH1_k127_1178718_0	522306.CAP2UW1_0968	1.063e-197	635.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
EH1_k127_1178718_5	1265490.JHVY01000006_gene2016	7.103e-71	251.0	COG0819@1|root,COG0819@2|Bacteria,1MVA0@1224|Proteobacteria,1RSHF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Long-chain fatty acid--CoA ligase	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
EH1_k127_1178718_2	522306.CAP2UW1_0970	8.258e-116	385.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,2VS3H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH1_k127_1178718_3	522306.CAP2UW1_0971	2.27e-89	299.0	COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,2VQ2E@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_8
EH1_k127_1178718_7	1163617.SCD_n01866	1.163e-67	234.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
EH1_k127_1178718_1	1123393.KB891333_gene2640	1.66e-127	419.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KSR8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
EH1_k127_1178718_6	1123393.KB891333_gene2641	1.014e-67	233.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH1_k127_1230725_2	292415.Tbd_0950	8.818e-187	591.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH1_k127_1230725_1	1123392.AQWL01000001_gene1634	8.141e-198	620.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1KS4U@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
EH1_k127_1230725_0	1123393.KB891329_gene1049	8.685e-237	745.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria,1KSQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
EH1_k127_1230725_5	1163617.SCD_n01605	9.157e-24	109.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,2VVZG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1230725_4	640081.Dsui_2927	2.287e-38	149.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KWNA@206389|Rhodocyclales	206389|Rhodocyclales	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
EH1_k127_1230725_3	292415.Tbd_0991	1.128e-50	188.0	COG0596@1|root,COG0596@2|Bacteria,1RJQK@1224|Proteobacteria,2W4YC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1230725_6	1348657.M622_01440	5.974e-10	62.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,2KX0V@206389|Rhodocyclales	206389|Rhodocyclales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
EH1_k127_1239502_4	1123392.AQWL01000001_gene1544	2.633e-23	106.0	COG1801@1|root,COG1801@2|Bacteria,1NJGC@1224|Proteobacteria,2WC6P@28216|Betaproteobacteria,1KT62@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1239502_1	1123392.AQWL01000001_gene1545	1.199e-124	406.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,1KS0M@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH1_k127_1239502_0	292415.Tbd_1899	9.864e-126	411.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KRYU@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
EH1_k127_1239502_2	977880.RALTA_A2884	1.385e-61	217.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH1_k127_1239502_3	1266925.JHVX01000011_gene1527	7.041e-57	204.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,3731H@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
EH1_k127_1255076_1	1132855.KB913035_gene935	3.164e-70	241.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,2KN0E@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
EH1_k127_1255076_0	1163617.SCD_n00522	4.592e-115	373.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria	28216|Betaproteobacteria	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
EH1_k127_1255076_3	1123392.AQWL01000004_gene2831	7.645e-66	229.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2VU4G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
EH1_k127_1255076_5	1123368.AUIS01000010_gene2364	3.216e-41	159.0	COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,1SAVI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
EH1_k127_1255076_4	395493.BegalDRAFT_3399	3.046e-41	163.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
EH1_k127_1255076_6	224911.27350827	5.466e-06	49.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1255076_2	1121035.AUCH01000016_gene2116	2.979e-66	230.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,2KV65@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
EH1_k127_1256213_2	1121382.JQKG01000015_gene1660	4.032e-17	89.0	2DP69@1|root,330Q1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1256213_1	1123393.KB891316_gene1304	7.729e-44	163.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria,1KSTX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
EH1_k127_1256213_0	292415.Tbd_1423	1.218e-141	456.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
EH1_k127_1262978_1	640081.Dsui_1124	1.309e-99	327.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,2KUBV@206389|Rhodocyclales	206389|Rhodocyclales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
EH1_k127_1262978_0	1249627.D779_0271	1.177e-194	634.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
EH1_k127_1268897_3	1123392.AQWL01000006_gene605	1.312e-55	197.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2WC4Z@28216|Betaproteobacteria,1KT6F@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrC like protein	-	-	-	-	-	-	-	-	-	-	-	-	DsrC
EH1_k127_1268897_4	398767.Glov_1182	2.147e-10	66.0	2DQXW@1|root,339A4@2|Bacteria,1NDBA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1268897_1	870187.Thini_1110	1.156e-74	260.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S4J0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
EH1_k127_1268897_2	748247.AZKH_1639	2.941e-57	219.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,2KW2Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
EH1_k127_1268897_0	62928.azo2920	8.64e-120	409.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
EH1_k127_1296045_1	292415.Tbd_0863	2.768e-92	308.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,1KRCU@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
EH1_k127_1296045_0	1123393.KB891317_gene2194	3.793e-142	460.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,1KSQR@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
EH1_k127_1296045_3	1123392.AQWL01000004_gene2641	0.0007057	48.0	2CI1Z@1|root,33EM5@2|Bacteria,1NPDN@1224|Proteobacteria,2VYXI@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1296045_2	1000565.METUNv1_02550	7.9e-40	150.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,2KVF9@206389|Rhodocyclales	206389|Rhodocyclales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
EH1_k127_1312532_2	1123393.KB891332_gene2790	2.956e-08	61.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1KRGP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ABC transporter C-terminal domain	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
EH1_k127_1312532_1	1163617.SCD_n00979	7.824e-20	95.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,2VY9Z@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM zinc finger, DksA TraR C4-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
EH1_k127_1312532_0	118168.MC7420_6665	2.012e-65	251.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria,1HI2A@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
EH1_k127_1317240_1	1123392.AQWL01000002_gene1903	2.137e-38	149.0	COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2VV8B@28216|Betaproteobacteria,1KT2D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
EH1_k127_1317240_0	85643.Tmz1t_3537	6.729e-64	230.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria,2KXTR@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH1_k127_1353337_1	1123517.JOMR01000001_gene211	9.167e-10	59.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,4606A@72273|Thiotrichales	72273|Thiotrichales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
EH1_k127_1353337_0	1500894.JQNN01000001_gene1035	9.013e-54	206.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,472A8@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HDOD,Pkinase
EH1_k127_1356965_0	1123393.KB891316_gene1450	2.075e-61	222.0	COG3221@1|root,COG3221@2|Bacteria,1PUJG@1224|Proteobacteria,2VKHU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH1_k127_1356965_1	358220.C380_10650	7.823e-25	116.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,Cache_3-Cache_2,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_3,PAS_4,PAS_9
EH1_k127_1371957_4	1454004.AW11_02355	1.294e-12	68.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria,1KQSG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
EH1_k127_1371957_1	1123368.AUIS01000023_gene926	1.568e-38	148.0	COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
EH1_k127_1371957_2	1454004.AW11_02355	9.013e-30	123.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria,1KQSG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
EH1_k127_1371957_3	1454004.AW11_02355	1.337e-13	78.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria,1KQSG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
EH1_k127_1371957_0	768671.ThimaDRAFT_0123	2.763e-77	262.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,1WY01@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM TIGR00645 family protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
EH1_k127_1394037_0	1191523.MROS_2033	3.132e-57	203.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
EH1_k127_1394037_2	1300143.CCAV010000004_gene2708	4.712e-21	104.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia,3ZPKI@59732|Chryseobacterium	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
EH1_k127_1394037_1	204669.Acid345_1306	7.652e-27	120.0	COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
EH1_k127_1394037_3	468059.AUHA01000002_gene1094	2.025e-09	60.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
EH1_k127_139511_2	62928.azo3801	9.997e-73	251.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,2KUF2@206389|Rhodocyclales	206389|Rhodocyclales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
EH1_k127_139511_1	266264.Rmet_1536	3.376e-136	441.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,1K4AY@119060|Burkholderiaceae	28216|Betaproteobacteria	KO	Hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
EH1_k127_139511_4	266264.Rmet_1535	2.726e-41	158.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VUFZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
EH1_k127_139511_3	1249627.D779_0042	2.933e-51	196.0	COG3259@1|root,COG3259@2|Bacteria,1RFVW@1224|Proteobacteria,1T354@1236|Gammaproteobacteria,1X2UT@135613|Chromatiales	135613|Chromatiales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
EH1_k127_139511_0	1121035.AUCH01000001_gene2026	0.0	1079.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,2KUXJ@206389|Rhodocyclales	206389|Rhodocyclales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
EH1_k127_1402538_0	338966.Ppro_3063	1.383e-95	321.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
EH1_k127_1402538_1	760142.Hipma_0269	2.887e-77	267.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
EH1_k127_1405503_0	522306.CAP2UW1_2602	6.034e-114	394.0	COG2202@1|root,COG2703@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
EH1_k127_1405503_1	443144.GM21_2797	5.368e-23	106.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,42R1Q@68525|delta/epsilon subdivisions,2WN15@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH1_k127_1406809_3	1165096.ARWF01000001_gene241	2.83e-05	51.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,2VVUJ@28216|Betaproteobacteria,2KN4M@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
EH1_k127_1406809_0	472759.Nhal_0304	1.497e-152	490.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
EH1_k127_1406809_1	522306.CAP2UW1_3961	4.966e-62	222.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,2VQHV@28216|Betaproteobacteria,1KQKZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
EH1_k127_1406809_2	159087.Daro_0487	2.25e-30	123.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,2KW35@206389|Rhodocyclales	206389|Rhodocyclales	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
EH1_k127_1422681_0	1163617.SCD_n02537	1.482e-150	485.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
EH1_k127_1422681_1	1123393.KB891316_gene1584	4.697e-24	104.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria,2VWBE@28216|Betaproteobacteria,1KT1N@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
EH1_k127_1425592_0	265072.Mfla_2074	2.628e-151	482.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KKET@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH1_k127_1425592_1	292415.Tbd_0656	1.75e-51	192.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the peptidase M17 family	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
EH1_k127_1426411_0	1123392.AQWL01000006_gene618	1.066e-128	417.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,1KS68@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
EH1_k127_1426411_1	296591.Bpro_3822	1.086e-106	365.0	COG4733@1|root,COG4733@2|Bacteria,1QYJ4@1224|Proteobacteria,2WHFV@28216|Betaproteobacteria,4AJWW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
EH1_k127_1426411_2	1123393.KB891326_gene21	5.852e-88	310.0	COG2426@1|root,COG2426@2|Bacteria,1N9Q5@1224|Proteobacteria	1224|Proteobacteria	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
EH1_k127_1440301_0	396588.Tgr7_0125	1.637e-98	339.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4CC@1236|Gammaproteobacteria,1X2QS@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
EH1_k127_1440487_1	1123393.KB891316_gene1527	1.065e-91	309.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KSFN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF853
EH1_k127_1440487_2	522306.CAP2UW1_1170	2.522e-86	291.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH1_k127_1440487_4	472759.Nhal_2244	1.627e-44	166.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria,1X0WB@135613|Chromatiales	135613|Chromatiales	J	PFAM Cold-shock protein, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
EH1_k127_1440487_3	1049564.TevJSym_ap00330	3.974e-48	176.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
EH1_k127_1440487_0	1123393.KB891316_gene1685	5.62e-133	429.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1KRE8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
EH1_k127_1446181_0	1415779.JOMH01000001_gene1470	4.371e-278	867.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1X3VS@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
EH1_k127_1461320_0	292415.Tbd_2767	1.773e-246	767.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,1KRA6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
EH1_k127_1461320_1	748280.NH8B_3565	5.013e-20	89.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KPY3@206351|Neisseriales	206351|Neisseriales	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
EH1_k127_1464489_1	640081.Dsui_3060	5.805e-73	249.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
EH1_k127_1464489_0	1163617.SCD_n00924	1.016e-169	535.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
EH1_k127_1465825_2	1163617.SCD_n01223	9.189e-77	259.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
EH1_k127_1465825_3	1163617.SCD_n01224	1.971e-59	216.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,2WGTY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
EH1_k127_1465825_0	1163617.SCD_n01225	8.718e-148	485.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH1_k127_1465825_4	1163617.SCD_n01226	2.596e-27	114.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
EH1_k127_1465825_1	1163617.SCD_n01227	1.889e-128	421.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
EH1_k127_1476808_1	582744.Msip34_0905	6.748e-139	447.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KKYP@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
EH1_k127_1476808_0	1123393.KB891317_gene2313	1.115e-150	481.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1KREP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
EH1_k127_1476808_2	265072.Mfla_1831	8.214e-55	202.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VYPK@28216|Betaproteobacteria,2KMQ0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
EH1_k127_1476808_4	1123392.AQWL01000004_gene2717	4.092e-39	151.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,1KRWE@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase III chi subunit, HolC	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol3_chi
EH1_k127_1476808_3	1485544.JQKP01000004_gene482	3.52e-40	151.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,44V9P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH1_k127_1491645_0	1000565.METUNv1_01567	3.447e-114	375.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria,2KZTK@206389|Rhodocyclales	206389|Rhodocyclales	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
EH1_k127_1491645_1	1123368.AUIS01000006_gene619	1.299e-33	130.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2ND6Z@225057|Acidithiobacillales	225057|Acidithiobacillales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH1_k127_1498427_0	1095769.CAHF01000005_gene1469	5.684e-105	346.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
EH1_k127_1498427_2	545276.KB898728_gene197	2.549e-35	147.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH1_k127_1498427_1	1485544.JQKP01000003_gene144	1.016e-66	235.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
EH1_k127_1498427_3	1123354.AUDR01000014_gene1001	9.083e-11	64.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,1KRZQ@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Kinase/pyrophosphorylase	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
EH1_k127_15023_0	1236689.MMALV_05010	2.359e-72	250.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2374	CPSase_L_D2,CPSase_L_D3,MGS
EH1_k127_15023_1	1033802.SSPSH_001953	1.311e-37	151.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH1_k127_1504243_2	1123393.KB891317_gene2400	2.284e-47	171.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KRCI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
EH1_k127_1504243_0	292415.Tbd_0893	4.748e-172	544.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KRCI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
EH1_k127_1504243_3	314345.SPV1_13352	5.756e-37	158.0	COG2199@1|root,COG3706@2|Bacteria,1QVPY@1224|Proteobacteria	1224|Proteobacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
EH1_k127_1504243_1	1123519.PSJM300_11590	9.381e-87	292.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1Z0H4@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
EH1_k127_1524481_0	1123393.KB891316_gene1327	7.312e-286	886.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1KRBT@119069|Hydrogenophilales	119069|Hydrogenophilales	CM	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
EH1_k127_1561675_0	1123367.C666_12935	1.052e-98	332.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,2KUAJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Ubiquinone biosynthesis hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,SE
EH1_k127_1561675_1	1123392.AQWL01000005_gene3065	7.138e-69	241.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,1KRYJ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Disulfide bond isomerase protein N-terminus	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
EH1_k127_1561675_2	644282.Deba_2293	6.584e-08	62.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
EH1_k127_1562128_1	1286106.MPL1_10507	2.866e-64	228.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_1562128_2	1121035.AUCH01000001_gene1816	6.226e-47	177.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria,2KW1T@206389|Rhodocyclales	206389|Rhodocyclales	T	ANTAR	-	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
EH1_k127_1562128_0	159087.Daro_1851	6.705e-66	228.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
EH1_k127_1569366_1	159087.Daro_0426	1.758e-57	201.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH1_k127_1569366_2	768671.ThimaDRAFT_0135	1.009e-20	98.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1X0VZ@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
EH1_k127_1569366_0	640081.Dsui_0673	9.33e-215	676.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
EH1_k127_1579094_1	1163617.SCD_n01940	2.489e-91	311.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
EH1_k127_1579094_2	335283.Neut_2288	5.605e-41	154.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,2WFUX@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
EH1_k127_1579094_3	1123392.AQWL01000001_gene1593	1.139e-24	113.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VWE5@28216|Betaproteobacteria,1KT8P@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1579094_0	1123367.C666_09385	3.051e-93	310.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,2KUVU@206389|Rhodocyclales	206389|Rhodocyclales	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
EH1_k127_1601335_2	1454004.AW11_00246	1.129e-32	127.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
EH1_k127_1601335_0	335543.Sfum_2338	9.152e-82	276.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42RMI@68525|delta/epsilon subdivisions,2WNHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
EH1_k127_1601335_1	76114.ebA1775	4.142e-69	239.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,2KUSE@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
EH1_k127_1606106_1	1123504.JQKD01000006_gene1481	8.881e-16	90.0	COG2885@1|root,COG2913@1|root,COG2885@2|Bacteria,COG2913@2|Bacteria,1RE53@1224|Proteobacteria,2VQ7S@28216|Betaproteobacteria,4AJRX@80864|Comamonadaceae	28216|Betaproteobacteria	JM	SmpA / OmlA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,SmpA_OmlA
EH1_k127_1606106_0	1123392.AQWL01000003_gene290	5.339e-104	339.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Inorganic H+ pyrophosphatase	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
EH1_k127_1623842_2	1123393.KB891326_gene142	5.393e-29	116.0	COG1436@1|root,COG1436@2|Bacteria,1MZUE@1224|Proteobacteria,2W5EY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (F/14-kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_F
EH1_k127_1623842_1	1123393.KB891326_gene143	2.512e-80	273.0	COG1390@1|root,COG1390@2|Bacteria,1R8BT@1224|Proteobacteria,2W49R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type proton ATPase subunit E	-	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
EH1_k127_1623842_0	1123393.KB891326_gene144	6.984e-125	402.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
EH1_k127_1637217_3	1255043.TVNIR_0796	4.906e-42	158.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1WZNN@135613|Chromatiales	135613|Chromatiales	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1637217_2	1123392.AQWL01000002_gene1850	6.505e-89	307.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,1KS1P@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
EH1_k127_1637217_0	1123401.JHYQ01000024_gene1272	1.504e-169	537.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,461RI@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH1_k127_1637217_1	1165096.ARWF01000001_gene2241	1.241e-148	479.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KKV0@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH1_k127_1637217_4	1283300.ATXB01000001_gene1723	4.111e-06	50.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,1S0NV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
EH1_k127_1639835_5	1192034.CAP_5118	1.725e-28	124.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
EH1_k127_1639835_3	640081.Dsui_2783	2.297e-101	342.0	COG2199@1|root,COG3706@2|Bacteria,1QWCN@1224|Proteobacteria,2VS5Y@28216|Betaproteobacteria,2KZQ8@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH1_k127_1639835_0	713586.KB900536_gene1549	0.0	1032.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales	135613|Chromatiales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
EH1_k127_1639835_4	1123393.KB891316_gene2128	1.542e-85	287.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,1KS2C@119069|Hydrogenophilales	119069|Hydrogenophilales	D	VirC1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
EH1_k127_1639835_2	1123392.AQWL01000006_gene545	2.933e-115	389.0	COG0129@1|root,COG0676@1|root,COG0129@2|Bacteria,COG0676@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,1KS6Q@119069|Hydrogenophilales	119069|Hydrogenophilales	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,ILVD_EDD
EH1_k127_1639835_1	1123393.KB891316_gene1858	1.733e-174	556.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,1KR9Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
EH1_k127_1639835_6	999541.bgla_1g04410	3.02e-18	85.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1K2D1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH1_k127_1683728_0	1163617.SCD_n01923	5.331e-197	622.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
EH1_k127_1683728_1	637389.Acaty_c0541	4.562e-190	608.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,2NC4Y@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
EH1_k127_1683728_2	323848.Nmul_A0718	4.182e-80	270.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,372V3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH1_k127_1701546_0	1123392.AQWL01000005_gene3215	2.351e-159	509.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,1KSAQ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
EH1_k127_1701546_2	637389.Acaty_c1626	2.025e-08	55.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,2NDT1@225057|Acidithiobacillales	225057|Acidithiobacillales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
EH1_k127_1701546_1	388051.AUFE01000033_gene3704	6.668e-09	57.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria	1224|Proteobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH1_k127_1707605_0	1340493.JNIF01000004_gene757	1.591e-79	274.0	COG5002@1|root,COG5002@2|Bacteria,3Y9FP@57723|Acidobacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,MASE1,MHYT,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,SBP_bac_3
EH1_k127_1707605_1	1232410.KI421426_gene1467	3.572e-22	104.0	2E5SP@1|root,330H2@2|Bacteria,1NDBY@1224|Proteobacteria	1224|Proteobacteria	S	YMGG-like Gly-zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA,Gly-zipper_YMGG
EH1_k127_1707605_2	85643.Tmz1t_1473	6.23e-21	93.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
EH1_k127_1710591_1	1049564.TevJSym_af00530	1.25e-145	481.0	28K74@1|root,2Z9VA@2|Bacteria,1R8MQ@1224|Proteobacteria,1SKKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1710591_0	1123392.AQWL01000004_gene2618	6.169e-261	827.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJJV@28216|Betaproteobacteria,1KSRR@119069|Hydrogenophilales	119069|Hydrogenophilales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH1_k127_1710591_3	1269813.ATUL01000032_gene1350	1.491e-46	193.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,1SEHY@1236|Gammaproteobacteria,1WZJM@135613|Chromatiales	135613|Chromatiales	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1710591_2	1123367.C666_06330	3.417e-72	249.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
EH1_k127_1730288_0	292415.Tbd_2727	8.472e-89	302.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
EH1_k127_1730288_2	85643.Tmz1t_3728	1.457e-23	102.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
EH1_k127_1730288_1	292415.Tbd_2726	7.551e-32	128.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1KTBP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
EH1_k127_1761188_1	1123393.KB891316_gene1515	9.925e-108	358.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KRY5@119069|Hydrogenophilales	119069|Hydrogenophilales	U	TolB amino-terminal domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
EH1_k127_1761188_6	1163617.SCD_n00675	6.39e-27	126.0	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell division and transport-associated protein TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
EH1_k127_1761188_4	1163617.SCD_n00674	2.651e-37	153.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Pfam Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
EH1_k127_1761188_2	1123392.AQWL01000005_gene2945	1.304e-76	262.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,1KSDC@119069|Hydrogenophilales	119069|Hydrogenophilales	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
EH1_k127_1761188_3	292415.Tbd_2210	2.593e-45	168.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,1KT2T@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
EH1_k127_1761188_0	748247.AZKH_0558	3.092e-180	568.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,2KUCP@206389|Rhodocyclales	206389|Rhodocyclales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
EH1_k127_1761188_5	1123504.JQKD01000034_gene2745	1.036e-30	123.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,4AAIH@80864|Comamonadaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
EH1_k127_1766950_1	338969.Rfer_0827	3.57e-143	468.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
EH1_k127_1766950_3	671143.DAMO_1018	6.708e-70	245.0	COG1335@1|root,COG1335@2|Bacteria,2NRK9@2323|unclassified Bacteria	2|Bacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000,ko01001	-	-	iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Isochorismatase
EH1_k127_1766950_0	1158292.JPOE01000002_gene1854	0.0	1116.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
EH1_k127_1766950_2	1121035.AUCH01000012_gene2992	8.925e-137	452.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGZJ@28216|Betaproteobacteria,2KVQZ@206389|Rhodocyclales	206389|Rhodocyclales	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_4
EH1_k127_1770168_2	1395571.TMS3_0101150	9.282e-44	167.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
EH1_k127_1770168_1	159087.Daro_0725	1.066e-60	211.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KWAN@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH1_k127_1770168_0	1485544.JQKP01000011_gene701	8.247e-105	358.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,44W69@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
EH1_k127_1828660_3	1286093.C266_18661	1.311e-44	163.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,1K6Y7@119060|Burkholderiaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
EH1_k127_1828660_2	243365.CV_1092	2.531e-49	180.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KRA2@206351|Neisseriales	206351|Neisseriales	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH1_k127_1828660_1	1163617.SCD_n01258	9.574e-57	202.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
EH1_k127_1828660_0	1163617.SCD_n01259	3.192e-183	578.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH1_k127_1834568_1	1123392.AQWL01000001_gene1436	5.154e-110	363.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
EH1_k127_1834568_4	247490.KSU1_C0507	1.711e-16	92.0	COG1361@1|root,COG1361@2|Bacteria,2IY9X@203682|Planctomycetes	203682|Planctomycetes	M	60 kDa outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
EH1_k127_1834568_2	631362.Thi970DRAFT_03837	1.099e-85	291.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1WWXR@135613|Chromatiales	135613|Chromatiales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
EH1_k127_1834568_5	1120977.JHUX01000008_gene537	1.508e-05	51.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria,3NNM4@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
EH1_k127_1834568_3	292415.Tbd_0984	1.109e-85	295.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
EH1_k127_1834568_0	580332.Slit_0533	2.159e-168	545.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
EH1_k127_1855457_0	1458357.BG58_40540	8.167e-102	346.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2VR2P@28216|Betaproteobacteria,1K78M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
EH1_k127_1855457_2	1123393.KB891331_gene2982	7.51e-18	92.0	2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1855457_1	1384054.N790_07735	1.272e-19	94.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1X82G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
EH1_k127_1864691_0	1163617.SCD_n01736	5.19e-257	801.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
EH1_k127_1887565_6	1123393.KB891329_gene998	1.625e-30	121.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,1KSH7@119069|Hydrogenophilales	119069|Hydrogenophilales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
EH1_k127_1887565_0	765910.MARPU_03440	3.171e-194	626.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
EH1_k127_1887565_1	1123392.AQWL01000008_gene1171	5.382e-105	356.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,1KSI8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
EH1_k127_1887565_2	335283.Neut_2178	6.812e-86	292.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,37229@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
EH1_k127_1887565_3	1163617.SCD_n01166	2.909e-85	289.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH1_k127_1887565_5	1298593.TOL_1843	4.346e-62	220.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
EH1_k127_1887565_4	1304883.KI912532_gene2114	3.648e-83	282.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,2KU7N@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH1_k127_1887565_7	1163617.SCD_n01837	7.322e-14	73.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2VXV9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Heavy metal-associated domain protein	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
EH1_k127_1887565_8	395019.Bmul_3023	8.98e-05	51.0	COG3418@1|root,COG3418@2|Bacteria,1NGUP@1224|Proteobacteria,2VXS1@28216|Betaproteobacteria,1K84H@119060|Burkholderiaceae	28216|Betaproteobacteria	N	PFAM FlgN family protein	flgN	-	-	ko:K02399	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgN
EH1_k127_1887565_9	1265502.KB905929_gene2173	0.0001348	45.0	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,2WAWA@28216|Betaproteobacteria,4AG1I@80864|Comamonadaceae	28216|Betaproteobacteria	N	Anti-sigma-28 factor, FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
EH1_k127_190660_1	1485544.JQKP01000003_gene94	5.301e-64	225.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,44VB5@713636|Nitrosomonadales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH1_k127_190660_0	1163617.SCD_n01964	5.129e-214	674.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH1_k127_1939527_2	292415.Tbd_0448	1.769e-48	181.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,2W98Q@28216|Betaproteobacteria,1KSVT@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
EH1_k127_1939527_0	1123392.AQWL01000005_gene2955	2.07e-111	373.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,1KREE@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
EH1_k127_1939527_1	292415.Tbd_2100	1.117e-51	185.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,1KSGC@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Alanine racemase, C-terminal domain	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
EH1_k127_1946086_0	1123393.KB891329_gene948	1.073e-222	702.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF1631,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_4
EH1_k127_1946086_1	1123392.AQWL01000004_gene2826	3.076e-137	446.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,1KSBK@119069|Hydrogenophilales	119069|Hydrogenophilales	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
EH1_k127_1964740_3	1218352.B597_003720	2.821e-43	168.0	COG5581@1|root,COG5581@2|Bacteria,1RCY3@1224|Proteobacteria,1S45F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
EH1_k127_1964740_1	1123392.AQWL01000001_gene1431	2.689e-60	219.0	COG0501@1|root,COG0501@2|Bacteria,1N5MJ@1224|Proteobacteria,2WBRD@28216|Betaproteobacteria,1KSF6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1964740_0	1123392.AQWL01000006_gene559	5.756e-74	254.0	2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,2W2XB@28216|Betaproteobacteria,1KSXF@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_1964740_2	279714.FuraDRAFT_2342	3.119e-56	200.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KQJG@206351|Neisseriales	206351|Neisseriales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
EH1_k127_1965826_5	1123393.KB891316_gene1322	1.305e-52	189.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,1KSJH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Rnf-Nqr subunit, membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
EH1_k127_1965826_3	1123392.AQWL01000001_gene1455	7.058e-62	224.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,1KSUU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
EH1_k127_1965826_1	1163617.SCD_n01981	4.643e-109	363.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
EH1_k127_1965826_0	1123392.AQWL01000001_gene1457	3.629e-195	623.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,1KSZA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,RnfC_N,SLBB
EH1_k127_1965826_2	395494.Galf_2364	4.188e-85	291.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
EH1_k127_1965826_4	1123392.AQWL01000001_gene1459	4.845e-56	197.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,1KSU1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Rnf-Nqr subunit, membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
EH1_k127_1965827_2	522306.CAP2UW1_1078	2.258e-65	228.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KQU5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
EH1_k127_1965827_0	1163617.SCD_n00080	1.813e-201	634.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria	28216|Betaproteobacteria	U	glutamate--cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
EH1_k127_1965827_1	1163617.SCD_n00081	5.912e-78	285.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
EH1_k127_1986751_0	757424.Hsero_0454	3.889e-128	416.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4724B@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
EH1_k127_1986751_1	640081.Dsui_0458	6.352e-114	371.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
EH1_k127_1986751_2	76114.ebB140	3.056e-18	86.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,2KXDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
EH1_k127_2007183_4	1267005.KB911261_gene2327	5.51e-05	49.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
EH1_k127_2007183_2	1437824.BN940_15521	1.974e-29	120.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,3T46K@506|Alcaligenaceae	28216|Betaproteobacteria	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
EH1_k127_2007183_0	1163617.SCD_n02208	6.781e-268	837.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
EH1_k127_2007183_1	1163617.SCD_n02207	5.107e-115	379.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
EH1_k127_2007183_3	526222.Desal_2705	5.787e-24	106.0	COG3391@1|root,COG3391@2|Bacteria,1N9KP@1224|Proteobacteria,42MVC@68525|delta/epsilon subdivisions,2X829@28221|Deltaproteobacteria,2MA80@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2008437_3	1000565.METUNv1_01638	2.755e-49	189.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria,2KWFR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2008437_2	1163617.SCD_n02226	1.784e-59	213.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
EH1_k127_2008437_1	153948.NAL212_0715	2.481e-98	337.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,3723W@32003|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like)	-	-	-	-	-	-	-	-	-	-	-	-	HAD
EH1_k127_2008437_0	1163617.SCD_n01819	1.72e-137	443.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	dctP	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
EH1_k127_2008957_2	1123367.C666_08835	4.85e-21	100.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KUGD@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3850 Signal transduction histidine kinase, nitrate nitrite-specific	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
EH1_k127_2008957_0	76114.ebA3504	2.385e-43	175.0	COG0664@1|root,COG0664@2|Bacteria,1RIIE@1224|Proteobacteria,2VTJF@28216|Betaproteobacteria,2KWQM@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	dnrE	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH1_k127_2008957_1	1121035.AUCH01000002_gene1483	2.779e-38	153.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,2KUND@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
EH1_k127_2026422_0	1123393.KB891326_gene83	1.573e-277	862.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
EH1_k127_2026422_1	62928.azo0588	2.905e-56	201.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria,2VVE7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2037840_0	1094184.KWO_0112840	2.029e-221	698.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,1SU7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K20327	ko02024,map02024	-	-	-	ko00000,ko00001,ko01003	-	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N
EH1_k127_2037840_4	1122180.Lokhon_01306	1.6e-31	143.0	28H81@1|root,2Z7K2@2|Bacteria,1NMZU@1224|Proteobacteria,2U5SR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial cellulose synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	BcsB
EH1_k127_2037840_5	314345.SPV1_08346	2.796e-19	102.0	COG3202@1|root,COG3202@2|Bacteria,1RCHN@1224|Proteobacteria	1224|Proteobacteria	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc4	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
EH1_k127_2037840_1	1198452.Jab_1c19330	6.983e-208	662.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,473TM@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	xanB	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
EH1_k127_2037840_2	1123393.KB891316_gene1084	7.373e-135	436.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,1KRNB@119069|Hydrogenophilales	119069|Hydrogenophilales	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
EH1_k127_2037840_3	1123393.KB891316_gene1085	2.123e-94	310.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1KRMV@119069|Hydrogenophilales	119069|Hydrogenophilales	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
EH1_k127_2076586_0	1158165.KB898872_gene1135	7.417e-220	693.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1RWY1@1236|Gammaproteobacteria,1X06S@135613|Chromatiales	135613|Chromatiales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9
EH1_k127_2084116_1	1163617.SCD_n00886	2.39e-39	153.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
EH1_k127_2084116_4	1123487.KB892838_gene3863	1.302e-06	55.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,2KWXH@206389|Rhodocyclales	206389|Rhodocyclales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
EH1_k127_2084116_3	62928.azo1051	1.998e-09	61.0	COG3087@1|root,COG3087@2|Bacteria,1QVC5@1224|Proteobacteria,2WGPN@28216|Betaproteobacteria,2KZVW@206389|Rhodocyclales	206389|Rhodocyclales	D	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
EH1_k127_2084116_2	292415.Tbd_1909	1.828e-27	123.0	COG1286@1|root,COG1286@2|Bacteria	2|Bacteria	S	toxin biosynthetic process	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
EH1_k127_2084116_0	323848.Nmul_A1906	1.043e-62	217.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
EH1_k127_2101971_0	713587.THITH_07505	1.941e-125	407.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,1RQ1I@1236|Gammaproteobacteria,1X08E@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
EH1_k127_2101971_1	768671.ThimaDRAFT_4409	1.267e-87	297.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,1WY71@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S binding domain	-	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
EH1_k127_2101971_2	749222.Nitsa_1608	1.19e-44	163.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YMEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
EH1_k127_2107134_2	670487.Ocepr_0430	4.098e-05	46.0	COG0437@1|root,COG0437@2|Bacteria,1WJ24@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
EH1_k127_2107134_1	867845.KI911784_gene2786	3.03e-105	353.0	COG5557@1|root,COG5557@2|Bacteria,2G703@200795|Chloroflexi	200795|Chloroflexi	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
EH1_k127_2107134_0	401526.TcarDRAFT_0235	5.027e-113	372.0	COG0243@1|root,COG0243@2|Bacteria,1UYJX@1239|Firmicutes	1239|Firmicutes	C	belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_2113850_2	864051.BurJ1DRAFT_2067	3.487e-34	132.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KMB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH1_k127_2113850_0	305700.B447_01101	3.421e-121	399.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KUSW@206389|Rhodocyclales	206389|Rhodocyclales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
EH1_k127_2113850_1	1123393.KB891317_gene2452	1.562e-36	143.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,1KS3I@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_2158643_2	1163617.SCD_n01941	1.75e-45	168.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
EH1_k127_2158643_4	1121035.AUCH01000015_gene2581	3.091e-08	59.0	2EA8Z@1|root,334DE@2|Bacteria,1NDKW@1224|Proteobacteria,2VVWJ@28216|Betaproteobacteria,2KXKV@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2158643_3	1123393.KB891317_gene2444	3.769e-31	129.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,1KRU2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Invasion gene expression up-regulator, SirB	-	-	-	-	-	-	-	-	-	-	-	-	SirB
EH1_k127_2158643_0	1304883.KI912532_gene730	9.921e-160	518.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,2KUN7@206389|Rhodocyclales	206389|Rhodocyclales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
EH1_k127_2158643_1	643562.Daes_2590	2.599e-78	269.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,43AMJ@68525|delta/epsilon subdivisions,2X61J@28221|Deltaproteobacteria,2M8KF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
EH1_k127_2160502_4	1316927.ATKI01000132_gene3951	1.203e-05	49.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,1S9NR@1236|Gammaproteobacteria,1YN03@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH1_k127_2160502_0	443144.GM21_2427	6.851e-232	724.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria	1224|Proteobacteria	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
EH1_k127_2160502_2	1304872.JAGC01000009_gene578	9.171e-111	382.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,42Z1I@68525|delta/epsilon subdivisions,2WTPW@28221|Deltaproteobacteria,2M8FP@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
EH1_k127_2160502_1	443144.GM21_2432	4.726e-135	440.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase, TatD	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
EH1_k127_2175092_1	1163617.SCD_n01805	4.729e-84	283.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
EH1_k127_2175092_0	945713.IALB_0863	2.025e-189	599.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	hao	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Multi-haem_cyto
EH1_k127_2175855_4	292415.Tbd_1773	2.618e-20	91.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,1KSJA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH1_k127_2175855_0	292415.Tbd_0514	3.077e-179	566.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1KRZJ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
EH1_k127_2175855_1	1502770.JQMG01000001_gene2225	3.564e-171	554.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KKNZ@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
EH1_k127_2175855_2	292415.Tbd_0516	6.601e-47	170.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KRPW@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
EH1_k127_2175855_3	1123393.KB891328_gene558	2.269e-31	124.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,1KRNR@119069|Hydrogenophilales	119069|Hydrogenophilales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
EH1_k127_2185431_1	1123393.KB891332_gene2729	1.441e-131	427.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,1KS4R@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
EH1_k127_2185431_2	1163617.SCD_n00750	1.489e-101	342.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
EH1_k127_2185431_3	265072.Mfla_0312	2.617e-38	144.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,2KN2K@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
EH1_k127_2185431_4	882378.RBRH_00925	5.603e-24	103.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,1KA4N@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
EH1_k127_2185431_0	292415.Tbd_2594	1.351e-167	532.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,1KSM9@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Transposase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
EH1_k127_2198754_1	1123393.KB891328_gene635	1.408e-56	198.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,1KREF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
EH1_k127_2198754_0	62928.azo0928	7.958e-173	553.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KUKY@206389|Rhodocyclales	206389|Rhodocyclales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
EH1_k127_2198754_2	381666.H16_A2362	1.497e-33	133.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,1K064@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
EH1_k127_2208910_1	1485544.JQKP01000004_gene441	2.869e-05	48.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2WGWV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
EH1_k127_2208910_0	640081.Dsui_1818	1.099e-91	311.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,2VH2D@28216|Betaproteobacteria,2KVGU@206389|Rhodocyclales	206389|Rhodocyclales	E	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH1_k127_2234680_0	1123393.KB891317_gene2207	3.352e-103	342.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
EH1_k127_2235400_1	626418.bglu_1g07830	3.124e-27	112.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VXF9@28216|Betaproteobacteria,1KAQV@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
EH1_k127_2235400_0	596154.Alide2_1768	5.234e-171	548.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH1_k127_2235400_2	640081.Dsui_1139	1.916e-24	102.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,2KYFQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH1_k127_2243022_1	1163617.SCD_n01800	2.318e-144	465.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
EH1_k127_2243022_0	1123393.KB891328_gene643	1.021e-151	488.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,1KSNH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	GTP-binding GTPase Middle Region	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
EH1_k127_2243022_2	426114.THI_2193	2.761e-31	123.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KM9R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
EH1_k127_225120_0	1123392.AQWL01000006_gene708	2.071e-112	385.0	COG0457@1|root,COG0457@2|Bacteria,1RFF6@1224|Proteobacteria,2W7RG@28216|Betaproteobacteria,1KRYC@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_225120_1	1123393.KB891331_gene2937	2.307e-33	134.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KSP1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
EH1_k127_225120_2	580332.Slit_1015	5.989e-31	126.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
EH1_k127_2278846_2	215803.DB30_0918	2.315e-17	85.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria,2YXTE@29|Myxococcales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
EH1_k127_2278846_1	640081.Dsui_1148	2.482e-49	184.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,2VR6M@28216|Betaproteobacteria,2KWDQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
EH1_k127_2278846_0	1123393.KB891316_gene1487	1.891e-93	321.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria,1KRQW@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2280421_6	1163617.SCD_n00601	4.135e-72	244.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
EH1_k127_2280421_0	292415.Tbd_1832	5.28e-230	715.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
EH1_k127_2280421_4	292415.Tbd_1831	9.468e-107	351.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1KRJ9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C1 family	-	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
EH1_k127_2280421_5	323848.Nmul_A1002	1.3e-104	342.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,372NI@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
EH1_k127_2280421_7	292415.Tbd_1829	2.366e-42	159.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
EH1_k127_2280421_8	1304883.KI912532_gene491	4.359e-16	91.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
EH1_k127_2280421_3	1163617.SCD_n01908	1.269e-128	424.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
EH1_k127_2280421_1	292415.Tbd_1520	8.254e-149	482.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,1KRDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
EH1_k127_2280421_2	640081.Dsui_3500	3.007e-143	468.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,2KV54@206389|Rhodocyclales	206389|Rhodocyclales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
EH1_k127_2280421_10	292415.Tbd_2463	9.998e-05	48.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KS03@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
EH1_k127_2283968_1	1123393.KB891316_gene1608	4.84e-115	374.0	COG2271@1|root,COG2271@2|Bacteria,1QYIR@1224|Proteobacteria,2WHF2@28216|Betaproteobacteria,1KS5F@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH1_k127_2283968_0	1123392.AQWL01000005_gene3034	1.216e-134	432.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
EH1_k127_2283968_3	1121920.AUAU01000012_gene2613	3.276e-43	161.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
EH1_k127_2283968_2	1123393.KB891316_gene1610	5.725e-58	203.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,1KSAZ@119069|Hydrogenophilales	119069|Hydrogenophilales	KP	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Rhodanese
EH1_k127_2286275_0	1163617.SCD_n02956	6.293e-136	437.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
EH1_k127_2286275_1	1163617.SCD_n02957	7.515e-128	423.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
EH1_k127_2320222_1	1123392.AQWL01000005_gene3195	2.414e-14	75.0	COG1977@1|root,COG1977@2|Bacteria,1PWRM@1224|Proteobacteria,2WCAB@28216|Betaproteobacteria,1KTBD@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
EH1_k127_2320222_0	1123392.AQWL01000006_gene669	1.729e-129	427.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KRJE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
EH1_k127_2328577_1	519989.ECTPHS_08943	6.409e-64	228.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,EAL,GGDEF,HATPase_c,HisKA,Hpt,Response_reg
EH1_k127_2328577_0	292415.Tbd_1268	5.581e-221	716.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,1NWAF@1224|Proteobacteria,2WGYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
EH1_k127_2328577_3	85643.Tmz1t_3846	4.476e-48	178.0	COG0642@1|root,COG2205@2|Bacteria,1QVTG@1224|Proteobacteria,2WGU8@28216|Betaproteobacteria,2KZPM@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
EH1_k127_2328577_2	292415.Tbd_1266	5.375e-59	209.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH1_k127_2333601_2	1163617.SCD_n02705	3.103e-15	84.0	COG0316@1|root,COG0316@2|Bacteria,1N8ZN@1224|Proteobacteria,2W5FR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulphur cluster biosynthesis	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH1_k127_2333601_0	1123392.AQWL01000005_gene3217	5.854e-178	569.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KRQV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,GATase_3
EH1_k127_2333601_1	1163617.SCD_n02707	9.653e-43	160.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
EH1_k127_2355840_1	279714.FuraDRAFT_3070	1.828e-14	80.0	COG3167@1|root,COG3167@2|Bacteria,1N685@1224|Proteobacteria,2VU7Q@28216|Betaproteobacteria,2KTN4@206351|Neisseriales	206351|Neisseriales	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2355840_3	292415.Tbd_1297	5.552e-12	74.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,2VVXW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
EH1_k127_2355840_2	1221522.B723_11840	2.477e-14	82.0	2DM2X@1|root,31HF3@2|Bacteria,1RIYM@1224|Proteobacteria,1SFV4@1236|Gammaproteobacteria,1YSNJ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2355840_0	1123368.AUIS01000016_gene2551	9.64e-229	718.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2NCBG@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
EH1_k127_2387857_6	1123393.KB891317_gene2434	0.0001385	46.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,2W5RM@28216|Betaproteobacteria,1KTDI@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2387857_5	402626.Rpic_2820	8.89e-49	180.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU5R@28216|Betaproteobacteria,1K7A9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
EH1_k127_2387857_4	1485544.JQKP01000012_gene2110	4.195e-116	382.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,44V19@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH1_k127_2387857_0	1123392.AQWL01000001_gene1354	1.058e-235	737.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
EH1_k127_2387857_3	1123393.KB891316_gene1431	6.071e-126	411.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2WH34@28216|Betaproteobacteria,1KSTU@119069|Hydrogenophilales	119069|Hydrogenophilales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	6PGD,NAD_binding_2
EH1_k127_2387857_1	395494.Galf_1328	3.25e-155	504.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,44V0E@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
EH1_k127_2387857_2	29581.BW37_05092	2.089e-141	469.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,4730W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
EH1_k127_2410549_2	292415.Tbd_1759	4.985e-20	94.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,1KRBJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
EH1_k127_2410549_1	1121035.AUCH01000001_gene1940	4.48e-41	164.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,2KW1R@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
EH1_k127_2410549_0	1158756.AQXQ01000012_gene2031	2.757e-93	316.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
EH1_k127_2410549_3	1123392.AQWL01000004_gene2623	1.536e-07	53.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH1_k127_2415349_2	292415.Tbd_2547	1.431e-70	244.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2415349_3	1123393.KB891316_gene2045	1.44e-69	238.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1KS9K@119069|Hydrogenophilales	119069|Hydrogenophilales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
EH1_k127_2415349_0	1123368.AUIS01000019_gene1232	2.485e-94	316.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,2NCXY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
EH1_k127_2415349_1	292415.Tbd_2669	1.566e-79	273.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,2W50B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
EH1_k127_2415349_4	1165096.ARWF01000001_gene2241	1.204e-45	167.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KKV0@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH1_k127_2419815_0	1123393.KB891327_gene315	4.131e-52	186.0	2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,2W8F1@28216|Betaproteobacteria,1KT4D@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2419815_2	1313301.AUGC01000015_gene1876	9.264e-28	126.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH1_k127_2419815_4	1384056.N787_13935	2.389e-10	66.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X525@135614|Xanthomonadales	135614|Xanthomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
EH1_k127_2419815_3	1123392.AQWL01000001_gene1364	4.751e-25	115.0	2A61N@1|root,30UTY@2|Bacteria,1Q9UM@1224|Proteobacteria,2W6WQ@28216|Betaproteobacteria,1KTCD@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2419815_1	1307759.JOMJ01000004_gene2828	1.164e-42	167.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
EH1_k127_2422554_0	323259.Mhun_1141	7.598e-164	521.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,2N916@224756|Methanomicrobia	224756|Methanomicrobia	G	PEP-utilising enzyme, TIM barrel domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH1_k127_2422554_1	1121920.AUAU01000010_gene52	3.155e-38	151.0	2DC1J@1|root,32TYP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2422554_2	153948.NAL212_0856	1.16e-11	69.0	2AHBD@1|root,317MV@2|Bacteria,1PYZC@1224|Proteobacteria,2WE3F@28216|Betaproteobacteria,374B6@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2455786_0	243365.CV_2520	7.821e-226	714.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KPKW@206351|Neisseriales	206351|Neisseriales	S	ABC transporter, ATP-binding protein	abcZ	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
EH1_k127_2473624_0	1123392.AQWL01000002_gene1812	1.906e-87	291.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,1KS58@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH1_k127_2473624_2	1123392.AQWL01000002_gene1813	5.198e-40	149.0	COG4327@1|root,COG4327@2|Bacteria,1NQBY@1224|Proteobacteria,2VV4C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
EH1_k127_2473624_1	1163617.SCD_n00480	2.687e-74	255.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH1_k127_2475362_7	1123392.AQWL01000001_gene1507	4.594e-57	199.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,1KSJA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH1_k127_2475362_1	572477.Alvin_0326	3.897e-170	554.0	COG1269@1|root,COG1269@2|Bacteria,1R6B8@1224|Proteobacteria,1RYT3@1236|Gammaproteobacteria,1WX8D@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
EH1_k127_2475362_5	1123392.AQWL01000002_gene1988	9.215e-75	255.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,1KS1M@119069|Hydrogenophilales	119069|Hydrogenophilales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
EH1_k127_2475362_9	292415.Tbd_0280	4.029e-36	141.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,1KT5M@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
EH1_k127_2475362_8	266264.Rmet_0227	1.073e-41	155.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,1K7RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
EH1_k127_2475362_6	1123393.KB891330_gene824	2.105e-67	241.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,1KRS6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
EH1_k127_2475362_3	1123392.AQWL01000002_gene2036	7.491e-127	422.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,1KRFG@119069|Hydrogenophilales	119069|Hydrogenophilales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
EH1_k127_2475362_4	1163617.SCD_n00156	1.254e-104	349.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
EH1_k127_2475362_0	1123392.AQWL01000002_gene1763	2.211e-227	711.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,1KT2B@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_2475362_2	292415.Tbd_2768	1.319e-140	449.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,1KRKU@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
EH1_k127_2486394_0	1163617.SCD_n01104	9.902e-105	348.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH1_k127_2486394_2	876269.ARWA01000001_gene2557	0.0006664	49.0	2ED3M@1|root,3370H@2|Bacteria,1NB6I@1224|Proteobacteria,2UE8V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2486394_1	76114.ebA6543	1.672e-23	101.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
EH1_k127_2523390_3	335543.Sfum_0408	1.926e-10	70.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
EH1_k127_2523390_2	156889.Mmc1_3202	5.597e-61	218.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH1_k127_2523390_0	292415.Tbd_1645	3.808e-162	526.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
EH1_k127_2523390_1	1123392.AQWL01000008_gene1154	3.359e-94	312.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria,1KSVN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
EH1_k127_2532919_1	65393.PCC7424_3835	3.557e-30	126.0	2BHDT@1|root,32BFT@2|Bacteria,1GMX4@1117|Cyanobacteria,3KKGC@43988|Cyanothece	1117|Cyanobacteria	S	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2532919_0	640511.BC1002_5549	6.609e-60	227.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
EH1_k127_2552544_8	1000565.METUNv1_02750	2.714e-39	147.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,2KU8F@206389|Rhodocyclales	206389|Rhodocyclales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
EH1_k127_2552544_5	580332.Slit_0325	3.737e-64	231.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH1_k127_2552544_6	946483.Cenrod_1481	5.641e-59	216.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,4A9WP@80864|Comamonadaceae	28216|Betaproteobacteria	DM	peptidase	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
EH1_k127_2552544_2	1123393.KB891317_gene2331	1.084e-117	399.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,1KRIA@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70 factor, region 1.2	-	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH1_k127_2552544_3	1123393.KB891317_gene2332	1.075e-81	281.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria,1KRXZ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH1_k127_2552544_7	292415.Tbd_0079	2.5e-48	184.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VTXX@28216|Betaproteobacteria,1KTD7@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Crp-like helix-turn-helix domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH1_k127_2552544_9	1266925.JHVX01000002_gene893	4.72e-34	135.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,373I3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
EH1_k127_2552544_0	1163617.SCD_n01127	2.276e-231	720.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_2552544_1	497321.C664_06623	1.911e-186	588.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KV2B@206389|Rhodocyclales	206389|Rhodocyclales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
EH1_k127_2552544_10	292415.Tbd_0843	7.592e-32	125.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,1KSFH@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
EH1_k127_2552544_4	1123401.JHYQ01000017_gene2538	2.466e-69	237.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,460QB@72273|Thiotrichales	72273|Thiotrichales	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
EH1_k127_2584799_0	582744.Msip34_1852	4.434e-177	563.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,2KKJA@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH1_k127_2584799_2	1132855.KB913035_gene966	5.082e-56	197.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,2KMYK@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM ferredoxin, 2Fe-2S type, ISC system	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
EH1_k127_2584799_4	292415.Tbd_1170	5.665e-28	113.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,1KTDJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Iron-sulphur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
EH1_k127_2584799_5	1349767.GJA_2916	5.742e-12	77.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2WGFK@28216|Betaproteobacteria,474T3@75682|Oxalobacteraceae	28216|Betaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH1_k127_2584799_1	768671.ThimaDRAFT_1043	2.709e-84	289.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1WXUX@135613|Chromatiales	135613|Chromatiales	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
EH1_k127_2607265_1	1123393.KB891316_gene1807	2.96e-109	359.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1KS77@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Coproporphyrinogen III oxidase	-	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
EH1_k127_2607265_2	243365.CV_0550	2.381e-61	218.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,2KR4H@206351|Neisseriales	206351|Neisseriales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
EH1_k127_2607265_0	1123392.AQWL01000005_gene3205	3.786e-187	590.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,1KS4T@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosylglycinamide synthetase, C domain	-	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
EH1_k127_2613916_1	1123392.AQWL01000001_gene1527	2.625e-53	203.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KRKB@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
EH1_k127_2613916_2	1123368.AUIS01000006_gene613	9.455e-16	85.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,1SIPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
EH1_k127_2613916_0	640081.Dsui_3194	1.465e-98	327.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,2KU8S@206389|Rhodocyclales	206389|Rhodocyclales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
EH1_k127_2624256_0	1175306.GWL_29320	1.472e-140	456.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4725T@75682|Oxalobacteraceae	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
EH1_k127_2624256_2	522306.CAP2UW1_1374	2.452e-88	298.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,1KQW1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
EH1_k127_2624256_1	1163617.SCD_n01244	1.363e-92	310.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
EH1_k127_2639753_0	398767.Glov_1443	5.013e-102	350.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,43T6I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_2640291_6	1408445.JHXP01000007_gene376	2.439e-05	47.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2640291_1	1123392.AQWL01000004_gene2597	1.562e-125	407.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,1KRK4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
EH1_k127_2640291_2	1163617.SCD_n01708	3.358e-113	370.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH1_k127_2640291_4	1123392.AQWL01000004_gene2594	5.748e-50	195.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,2VU2H@28216|Betaproteobacteria,1KS4N@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2640291_0	292415.Tbd_0693	0.0	1131.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,1KS6C@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
EH1_k127_2640291_5	292415.Tbd_0694	1.547e-38	146.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,1KTA2@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
EH1_k127_2640291_3	305700.B447_03748	2.472e-103	343.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,2KVRT@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
EH1_k127_2640291_7	75379.Tint_1843	0.0002061	44.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2W8XA@28216|Betaproteobacteria,1KPEJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH1_k127_265046_1	1123393.KB891333_gene2599	9.367e-16	78.0	COG0664@1|root,COG1295@1|root,COG0664@2|Bacteria,COG1295@2|Bacteria,1PWBZ@1224|Proteobacteria,2VY5Z@28216|Betaproteobacteria,1KSQT@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB,cNMP_binding
EH1_k127_265046_0	497321.C664_00915	2.492e-292	914.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
EH1_k127_265929_1	748280.NH8B_0739	5.977e-42	156.0	COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,2WFE6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	hydratase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
EH1_k127_265929_0	580332.Slit_2532	1.323e-240	752.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
EH1_k127_2675040_0	1163617.SCD_n01727	3.951e-186	584.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH1_k127_2675040_1	292415.Tbd_0871	3.382e-143	460.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,2W1RG@28216|Betaproteobacteria,1KS0P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH1_k127_2675040_2	1123368.AUIS01000001_gene1863	5.984e-06	53.0	2EIBB@1|root,33C2R@2|Bacteria,1PS8K@1224|Proteobacteria,1ST8B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2695127_0	497321.C664_10772	2.865e-196	617.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,2KVP0@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
EH1_k127_2695127_4	1485544.JQKP01000001_gene1253	1.116e-116	380.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,44WBY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_2695127_1	1123393.KB891327_gene472	7.66e-133	429.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Zinc iron permease	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
EH1_k127_2695127_6	748247.AZKH_3142	1.848e-94	315.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KUES@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
EH1_k127_2695127_3	305700.B447_01346	1.952e-118	390.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,2KV8G@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH1_k127_2695127_5	1123392.AQWL01000004_gene2514	4.462e-105	347.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KREX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
EH1_k127_2695127_2	1120999.JONM01000003_gene2782	8.092e-127	417.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KPJR@206351|Neisseriales	206351|Neisseriales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH1_k127_2717300_3	391625.PPSIR1_36127	3.053e-26	117.0	COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,42QG0@68525|delta/epsilon subdivisions,2WJE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
EH1_k127_2717300_1	420662.Mpe_A0051	3.677e-77	272.0	COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,2VJH0@28216|Betaproteobacteria,1KK3C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
EH1_k127_2717300_2	1198452.Jab_2c31890	3.238e-71	254.0	COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,2VR22@28216|Betaproteobacteria,476UN@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
EH1_k127_2717300_0	1049564.TevJSym_at00530	0.0	1226.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
EH1_k127_2717300_4	305700.B447_04048	1.064e-06	52.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,2KWTZ@206389|Rhodocyclales	206389|Rhodocyclales	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
EH1_k127_273024_0	1123392.AQWL01000002_gene1985	8.317e-224	699.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,1KRB4@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
EH1_k127_273024_4	1304883.KI912532_gene581	1.626e-35	137.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,2KWZ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the frataxin	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
EH1_k127_273024_1	1163617.SCD_n00173	2.179e-171	547.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
EH1_k127_273024_6	1123392.AQWL01000002_gene1977	1.386e-05	53.0	2AFZ2@1|root,3162V@2|Bacteria,1PWRF@1224|Proteobacteria,2WCA6@28216|Betaproteobacteria,1KTB4@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_273024_3	396588.Tgr7_2426	1.262e-49	179.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria,1WYEG@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
EH1_k127_273024_2	1304883.KI912532_gene615	6.453e-76	267.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,2KXTJ@206389|Rhodocyclales	206389|Rhodocyclales	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_273024_5	265072.Mfla_0204	1.37e-20	93.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,2KKKA@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM DnaA regulatory inactivator Hda	-	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
EH1_k127_2737058_1	1000565.METUNv1_03850	1.722e-46	168.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,2KV9H@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
EH1_k127_2737058_0	1163617.SCD_n02082	1.136e-213	683.0	COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,2VJ7F@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
EH1_k127_2807127_3	1485544.JQKP01000002_gene1535	1.82e-52	187.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
EH1_k127_2807127_2	1123393.KB891331_gene2890	3.182e-59	207.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,1KRVB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
EH1_k127_2807127_0	1123392.AQWL01000002_gene1930	5.82e-207	652.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,1KSW6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	-	-	-	-	-	-	-	-	-	-	GDC-P
EH1_k127_2807127_1	1217718.ALOU01000037_gene2107	1.735e-68	237.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria,1K3UI@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
EH1_k127_2807127_4	323261.Noc_2547	5.131e-21	94.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
EH1_k127_2808716_0	292415.Tbd_1159	3.803e-183	582.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,1KRJ3@119069|Hydrogenophilales	119069|Hydrogenophilales	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
EH1_k127_2808716_1	1049564.TevJSym_ad00410	1.083e-39	153.0	2E8HY@1|root,332W0@2|Bacteria,1N9SS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2808716_2	292415.Tbd_1102	1.49e-21	100.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
EH1_k127_2842897_1	1123392.AQWL01000018_gene70	6.489e-47	171.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,1KRDC@119069|Hydrogenophilales	119069|Hydrogenophilales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
EH1_k127_2842897_0	292415.Tbd_0436	9.281e-231	719.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,1KRAC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
EH1_k127_2866002_2	1232410.KI421421_gene3874	7.142e-14	76.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42QT6@68525|delta/epsilon subdivisions,2WNC5@28221|Deltaproteobacteria,43W1X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
EH1_k127_2866002_0	573.JG24_06935	5.244e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
EH1_k127_2866002_1	94624.Bpet2465	5.065e-64	229.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,2VHKW@28216|Betaproteobacteria,3T6DM@506|Alcaligenaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
EH1_k127_2875604_0	1163617.SCD_n00764	1.6e-111	363.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
EH1_k127_2875604_1	1163617.SCD_n00765	4.725e-49	181.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Hydrogenase expression formation protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
EH1_k127_2899968_0	243233.MCA1761	1.789e-269	848.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XDXD@135618|Methylococcales	135618|Methylococcales	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH1_k127_2903691_1	1009370.ALO_18502	9.243e-19	95.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,4H4IN@909932|Negativicutes	909932|Negativicutes	S	Sel1 repeat protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_7
EH1_k127_2903691_0	292415.Tbd_0212	7.282e-103	340.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,1KSYK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH1_k127_2907010_2	1123368.AUIS01000001_gene2128	3.555e-97	323.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,2NC65@225057|Acidithiobacillales	225057|Acidithiobacillales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
EH1_k127_2907010_0	1163617.SCD_n01264	2.405e-135	446.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
EH1_k127_2907010_5	640081.Dsui_1725	6.868e-10	70.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,2KUF4@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA
EH1_k127_2907010_3	292415.Tbd_1180	3.814e-84	285.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,1KS9X@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
EH1_k127_2907010_1	1163617.SCD_n01267	8.274e-101	333.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH1_k127_2907010_4	522306.CAP2UW1_3828	7.146e-76	261.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria,1KR46@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB1	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH1_k127_2915117_3	438753.AZC_3853	1.143e-16	79.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,2UHAM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
EH1_k127_2915117_0	1158182.KB905021_gene524	1.223e-204	645.0	28IVT@1|root,2Z8U5@2|Bacteria,1R7G9@1224|Proteobacteria,1S02A@1236|Gammaproteobacteria,1WXJ0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2915117_4	441620.Mpop_5133	0.0001689	46.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
EH1_k127_2915117_2	1123393.KB891331_gene2927	2.452e-69	244.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,1KT00@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_2915117_1	582744.Msip34_1063	1.315e-194	616.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KM7U@206350|Nitrosomonadales	206350|Nitrosomonadales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH1_k127_2923667_0	1288494.EBAPG3_3240	1.417e-185	596.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,371WG@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686,ko:K19597	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.5.20	-	-	E1-E2_ATPase,HMA,Hydrolase
EH1_k127_2925815_1	1123392.AQWL01000001_gene1449	1.022e-141	456.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1KRBT@119069|Hydrogenophilales	119069|Hydrogenophilales	CM	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
EH1_k127_2925815_0	1123392.AQWL01000001_gene1448	9.15e-154	491.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,1KRDA@119069|Hydrogenophilales	119069|Hydrogenophilales	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
EH1_k127_2925815_2	883126.HMPREF9710_02254	3.465e-06	57.0	2D0EJ@1|root,32T8E@2|Bacteria,1N5EU@1224|Proteobacteria,2VV4T@28216|Betaproteobacteria,476MC@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2940865_4	1123393.KB891330_gene860	6.351e-36	139.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria,1KST1@119069|Hydrogenophilales	119069|Hydrogenophilales	K	transmembrane transcriptional regulator (Anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2940865_0	292415.Tbd_1654	1.022e-70	242.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,1KT1T@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH1_k127_2940865_2	1123393.KB891330_gene862	1.402e-49	182.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,2VU7D@28216|Betaproteobacteria,1KT5V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
EH1_k127_2940865_1	864051.BurJ1DRAFT_4367	1.898e-60	215.0	2DKVG@1|root,30GRY@2|Bacteria,1RDQT@1224|Proteobacteria,2VVQC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
EH1_k127_2940865_3	1122236.KB905141_gene1334	4.449e-42	174.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2VSKQ@28216|Betaproteobacteria,2KP39@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH1_k127_2940865_5	292415.Tbd_1227	2.081e-27	111.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
EH1_k127_2948995_1	926560.KE387023_gene2722	1.634e-79	277.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
EH1_k127_2948995_0	398767.Glov_1986	1.559e-91	312.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH1_k127_2954914_2	640081.Dsui_2528	1.068e-57	212.0	COG0515@1|root,COG1639@1|root,COG2203@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,2KUM0@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HDOD,Pkinase
EH1_k127_2954914_0	1163617.SCD_n02204	8.855e-222	695.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
EH1_k127_2954914_1	159087.Daro_2851	4.012e-145	462.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KUBN@206389|Rhodocyclales	206389|Rhodocyclales	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH1_k127_2981050_4	1163617.SCD_n01987	3.689e-43	160.0	COG4398@1|root,COG4398@2|Bacteria,1RBRR@1224|Proteobacteria,2VQ7K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
EH1_k127_2981050_3	1123393.KB891316_gene1325	5.414e-53	192.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,1KT4F@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
EH1_k127_2981050_0	1123392.AQWL01000001_gene1443	1.436e-240	769.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1KSX1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH1_k127_2981050_2	342113.DM82_2513	6.662e-54	216.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1K1TA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
EH1_k127_2981050_5	768671.ThimaDRAFT_3514	6.167e-12	70.0	2BVMS@1|root,2ZD7A@2|Bacteria,1P839@1224|Proteobacteria,1STHW@1236|Gammaproteobacteria,1X1K8@135613|Chromatiales	135613|Chromatiales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_2981050_1	1163617.SCD_n01212	8.332e-65	226.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VKS0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_2996256_3	1121438.JNJA01000007_gene1645	2.133e-53	190.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
EH1_k127_2996256_1	580332.Slit_0302	2.862e-82	275.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,44WN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
EH1_k127_2996256_0	580332.Slit_0303	3.405e-261	807.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
EH1_k127_2996256_2	1049564.TevJSym_bd00250	8.208e-79	271.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
EH1_k127_2997420_0	522306.CAP2UW1_0607	0.0	1331.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KQDX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	mdtC	-	-	ko:K03296,ko:K07788,ko:K07789,ko:K21133	ko02020,map02020	M00648,M00822	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2,2.A.6.2.35	-	-	ACR_tran
EH1_k127_2997420_1	1304883.KI912532_gene1993	1.971e-37	144.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,2KUIM@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	HlyD_D23
EH1_k127_3000941_0	305700.B447_16201	1.039e-137	444.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH1_k127_3000941_3	748280.NH8B_0218	3.436e-06	55.0	COG4701@1|root,COG4701@2|Bacteria,1PK4W@1224|Proteobacteria,2WE1P@28216|Betaproteobacteria,2KSAH@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
EH1_k127_3000941_2	1123392.AQWL01000002_gene1959	3.733e-61	223.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,1KRQ3@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Shikimate kinase	-	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
EH1_k127_3000941_1	1123392.AQWL01000002_gene1960	1.338e-68	247.0	2DBH8@1|root,2Z982@2|Bacteria,1MXUE@1224|Proteobacteria,2VP20@28216|Betaproteobacteria,1KSZB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3006623_2	292415.Tbd_2388	1.604e-70	245.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,1KRFV@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH1_k127_3006623_0	1121035.AUCH01000005_gene60	4.426e-163	531.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales	206389|Rhodocyclales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
EH1_k127_3006623_4	640511.BC1002_5277	3.317e-49	185.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,1K70P@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
EH1_k127_3006623_5	522306.CAP2UW1_0459	2.299e-30	121.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,1KQ3W@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
EH1_k127_3006623_1	1123392.AQWL01000005_gene3124	1.308e-151	487.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,1KRBP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
EH1_k127_3006623_3	1123392.AQWL01000005_gene3123	5.21e-64	228.0	28P17@1|root,2ZBXM@2|Bacteria,1RCPK@1224|Proteobacteria,2VZ64@28216|Betaproteobacteria,1KSBN@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3006623_6	754477.Q7C_2017	1.106e-09	61.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,460RW@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
EH1_k127_3009602_0	1123368.AUIS01000019_gene1219	3.556e-97	335.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
EH1_k127_3009602_1	1121035.AUCH01000017_gene2261	4.132e-43	171.0	COG2259@1|root,COG2259@2|Bacteria,1RDRZ@1224|Proteobacteria,2VS2G@28216|Betaproteobacteria,2KYXS@206389|Rhodocyclales	206389|Rhodocyclales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
EH1_k127_3009602_2	1485544.JQKP01000007_gene1968	7.468e-17	89.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,44VRA@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
EH1_k127_3013908_1	1123393.KB891330_gene860	2.031e-86	290.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria,1KST1@119069|Hydrogenophilales	119069|Hydrogenophilales	K	transmembrane transcriptional regulator (Anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3013908_0	1123392.AQWL01000004_gene2827	8.651e-119	386.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1KRSX@119069|Hydrogenophilales	119069|Hydrogenophilales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
EH1_k127_3013908_2	1038869.AXAN01000012_gene6490	2.372e-14	74.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,1K09W@119060|Burkholderiaceae	28216|Betaproteobacteria	O	serine protease	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
EH1_k127_3023918_0	396588.Tgr7_0340	1.18e-321	989.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1WWPF@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_303234_1	1123392.AQWL01000002_gene2118	1.79e-144	475.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,1KRQB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
EH1_k127_303234_4	1123393.KB891330_gene738	1.076e-37	149.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria,1KS6V@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Outer membrane lipoprotein LolB	-	-	-	-	-	-	-	-	-	-	-	-	LolB
EH1_k127_303234_2	1163617.SCD_n02623	1.413e-108	360.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
EH1_k127_303234_0	292415.Tbd_0387	2.708e-170	539.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KRHN@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
EH1_k127_303234_3	1123392.AQWL01000002_gene2122	1.46e-68	236.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,1KRND@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal L25p family	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
EH1_k127_3055016_0	1123392.AQWL01000002_gene1812	2.311e-293	909.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,1KS58@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH1_k127_3055016_2	1123392.AQWL01000002_gene1811	1.578e-59	212.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
EH1_k127_3055016_3	1123392.AQWL01000002_gene1810	2.271e-40	153.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3055016_1	85643.Tmz1t_4080	1.372e-179	567.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,2KV0I@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
EH1_k127_3055016_4	640081.Dsui_0292	2.346e-13	76.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria,2KWBB@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH1_k127_3083879_2	1005048.CFU_4077	5.473e-22	96.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,473VI@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
EH1_k127_3083879_0	765912.Thimo_0377	1.081e-148	486.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1X2UX@135613|Chromatiales	135613|Chromatiales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
EH1_k127_3083879_1	765912.Thimo_0378	1.376e-95	323.0	COG0730@1|root,COG0730@2|Bacteria,1R3ZH@1224|Proteobacteria,1T14N@1236|Gammaproteobacteria,1WZW6@135613|Chromatiales	135613|Chromatiales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH1_k127_3083879_3	667014.Thein_2231	3.901e-21	99.0	COG1462@1|root,COG1462@2|Bacteria,2GI15@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
EH1_k127_308792_3	1120985.AUMI01000017_gene2729	9.065e-49	181.0	COG2930@1|root,COG2930@2|Bacteria,1VBSP@1239|Firmicutes,4H54G@909932|Negativicutes	909932|Negativicutes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
EH1_k127_308792_5	292415.Tbd_0486	9.116e-31	124.0	2ECQ3@1|root,336MT@2|Bacteria,1NB5U@1224|Proteobacteria,2VVY5@28216|Betaproteobacteria,1KT8B@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_308792_2	693444.D782_2262	2.609e-110	373.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
EH1_k127_308792_1	1163617.SCD_n01152	6.415e-142	460.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_308792_0	1163617.SCD_n01153	1.525e-201	634.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_308792_7	497321.C664_17487	4.425e-15	74.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria,2KXEJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH1_k127_3106254_0	1123393.KB891328_gene657	6.003e-86	292.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KSC3@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH1_k127_3106254_2	1163617.SCD_n01942	1.708e-42	166.0	COG2203@1|root,COG2203@2|Bacteria,1RG7F@1224|Proteobacteria,2VUF7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
EH1_k127_3106254_1	265072.Mfla_2479	1.462e-68	237.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KMKC@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
EH1_k127_311581_2	292415.Tbd_1533	3.548e-24	104.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KTA7@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
EH1_k127_311581_1	637390.AFOH01000107_gene157	4.692e-90	306.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,2NCG9@225057|Acidithiobacillales	225057|Acidithiobacillales	O	DnaJ C terminal domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
EH1_k127_311581_0	933262.AXAM01000005_gene2536	8.481e-100	338.0	COG0457@1|root,COG0457@2|Bacteria,1NK18@1224|Proteobacteria,42SRA@68525|delta/epsilon subdivisions,2WPJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
EH1_k127_3120205_3	76114.ebA3238	2.039e-17	87.0	2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2VUDK@28216|Betaproteobacteria,2KX1H@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3120205_0	1123392.AQWL01000011_gene2256	1.848e-212	665.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,1KRWZ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
EH1_k127_3120205_1	582744.Msip34_0971	1.412e-93	312.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,2KMJ9@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
EH1_k127_3120205_2	265072.Mfla_2151	3.373e-62	221.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,2KKW8@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
EH1_k127_3135761_2	396588.Tgr7_2031	1.779e-25	107.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1WVZF@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
EH1_k127_3135761_1	292415.Tbd_1575	1.296e-30	128.0	2CHMP@1|root,2ZJFK@2|Bacteria,1P479@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3135761_0	1163617.SCD_n00749	2.634e-133	432.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
EH1_k127_3136767_1	1163617.SCD_n02918	1.244e-103	348.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
EH1_k127_3136767_2	1123367.C666_04955	2.08e-91	309.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,2KUT0@206389|Rhodocyclales	206389|Rhodocyclales	M	3-Deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
EH1_k127_3136767_3	1163617.SCD_n02917	5.05e-34	134.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
EH1_k127_3136767_0	1123392.AQWL01000006_gene570	1.303e-174	551.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,1KRB7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Polysaccharide biosynthesis protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
EH1_k127_3148528_1	292415.Tbd_2668	5.945e-130	423.0	COG0152@1|root,COG0628@1|root,COG0152@2|Bacteria,COG0628@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,1KSDD@119069|Hydrogenophilales	119069|Hydrogenophilales	F	SAICAR synthetase	-	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	AI-2E_transport,SAICAR_synt
EH1_k127_3148528_0	1123393.KB891331_gene2907	1.056e-177	557.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KRDZ@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
EH1_k127_3151122_0	1123392.AQWL01000001_gene1575	5.092e-211	663.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,1KRED@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Zinc finger found in FPG and IleRS	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
EH1_k127_3151122_2	204773.HEAR0844	2.56e-54	199.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,474BH@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
EH1_k127_3151122_3	999541.bgla_1g32030	4.094e-28	125.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,1K0EI@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH1_k127_3151122_1	1123393.KB891316_gene1145	4.746e-151	490.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KRES@119069|Hydrogenophilales	119069|Hydrogenophilales	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
EH1_k127_3154349_5	765913.ThidrDRAFT_2678	2.011e-11	68.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WWDP@135613|Chromatiales	135613|Chromatiales	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
EH1_k127_3154349_0	1163617.SCD_n01847	1.273e-217	687.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
EH1_k127_3154349_2	1502770.JQMG01000001_gene162	2.34e-56	198.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KMZX@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
EH1_k127_3154349_6	1123368.AUIS01000005_gene480	0.0008329	48.0	COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3154349_4	1163617.SCD_n02497	2.126e-22	104.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,DUF302
EH1_k127_3154349_1	765910.MARPU_02400	8.858e-75	261.0	COG0697@1|root,COG0697@2|Bacteria,1RJFE@1224|Proteobacteria,1RZF0@1236|Gammaproteobacteria,1WWYW@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH1_k127_3154349_3	1123393.KB891328_gene528	8.708e-52	184.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,1KRPC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH1_k127_3200233_1	1163617.SCD_n00481	2.272e-127	419.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
EH1_k127_3200233_0	870187.Thini_2438	2.63e-315	979.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,463PR@72273|Thiotrichales	72273|Thiotrichales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH1_k127_3200233_2	1123399.AQVE01000001_gene754	2.846e-47	172.0	COG3162@1|root,COG3162@2|Bacteria,1N9T2@1224|Proteobacteria,1SSS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
EH1_k127_3200233_3	426114.THI_3222	6.356e-23	100.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1KK1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM response regulator receiver	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_322106_1	1163617.SCD_n01501	1.053e-103	340.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH1_k127_322106_2	1123368.AUIS01000001_gene1993	4.234e-61	231.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
EH1_k127_322106_0	1123368.AUIS01000019_gene1227	1.372e-225	713.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	apc3	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
EH1_k127_3224012_2	1123392.AQWL01000004_gene2679	5.381e-88	304.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KSC3@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH1_k127_3224012_1	1123368.AUIS01000007_gene2814	1.95e-129	427.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
EH1_k127_3224012_0	1123392.AQWL01000001_gene1357	1.995e-156	497.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase, U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
EH1_k127_3225895_0	395494.Galf_2294	6.536e-157	499.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
EH1_k127_3225895_2	935839.JAGJ01000004_gene2048	2.975e-13	80.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
EH1_k127_3225895_1	292415.Tbd_2815	6.372e-40	158.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KS5H@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
EH1_k127_3231353_1	1163617.SCD_n02495	1.04e-75	261.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3231353_0	748247.AZKH_3583	4.821e-158	503.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,2KVGB@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
EH1_k127_3231353_2	62928.azo3243	5.419e-12	66.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,2KWPP@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
EH1_k127_3239098_0	292415.Tbd_2362	1.164e-127	421.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1KSXX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
EH1_k127_3239098_1	1123392.AQWL01000005_gene3099	9.704e-46	169.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KSKP@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
EH1_k127_3241022_8	349161.Dred_1723	3.386e-10	60.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,261CR@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH1_k127_3241022_3	1003200.AXXA_30032	1.406e-92	309.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,3T3A0@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH1_k127_3241022_5	292415.Tbd_2724	6.313e-56	203.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
EH1_k127_3241022_6	1163617.SCD_n02858	2.828e-31	126.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
EH1_k127_3241022_0	292415.Tbd_2507	3.675e-218	692.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KSNF@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
EH1_k127_3241022_2	396588.Tgr7_1031	1.271e-95	322.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1WXFV@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
EH1_k127_3241022_1	1123392.AQWL01000003_gene491	1.591e-150	482.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KS1H@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
EH1_k127_3241022_4	887898.HMPREF0551_0442	1.468e-60	213.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,1K81Q@119060|Burkholderiaceae	28216|Betaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein b	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
EH1_k127_3241022_7	640081.Dsui_2152	3.39e-29	119.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,2KVAD@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
EH1_k127_3245452_0	243365.CV_3450	1.018e-209	664.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KU4G@206351|Neisseriales	206351|Neisseriales	NT	Chemotaxis protein CheA	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH1_k127_3245452_1	1163617.SCD_n01220	6.442e-75	259.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
EH1_k127_3255595_0	748280.NH8B_1555	4.121e-151	497.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQJ6@206351|Neisseriales	206351|Neisseriales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,Response_reg
EH1_k127_3265854_0	580332.Slit_2488	2.666e-152	487.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VM3P@28216|Betaproteobacteria,44W59@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH1_k127_3265854_1	580332.Slit_2487	8.228e-130	419.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,2VKNM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
EH1_k127_3274893_1	637389.Acaty_m0029	2.393e-113	374.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,2NC5M@225057|Acidithiobacillales	225057|Acidithiobacillales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
EH1_k127_3274893_0	1485544.JQKP01000020_gene70	3.079e-252	784.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,44W6Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
EH1_k127_3274893_4	1123269.NX02_08845	3.923e-06	56.0	2EIBB@1|root,33C2R@2|Bacteria,1NH1Q@1224|Proteobacteria,2UJX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3274893_3	272942.RCAP_rcc02638	4.24e-09	64.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2VAV1@28211|Alphaproteobacteria,1FC50@1060|Rhodobacter	28211|Alphaproteobacteria	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
EH1_k127_3274893_2	251221.35214669	3.426e-56	205.0	COG1075@1|root,COG1075@2|Bacteria,1G60C@1117|Cyanobacteria	1117|Cyanobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
EH1_k127_3278239_2	765911.Thivi_0315	1.571e-64	224.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,1SBPR@1236|Gammaproteobacteria,1WY4R@135613|Chromatiales	135613|Chromatiales	NT	CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
EH1_k127_3278239_3	572477.Alvin_2461	5.686e-49	177.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	EAL,LytTR,Response_reg
EH1_k127_3278239_1	402626.Rpic_2716	1.498e-99	333.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,1K2JS@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
EH1_k127_3278239_0	62928.azo1566	3.7e-322	994.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH1_k127_3282390_4	1123393.KB891326_gene133	3.131e-42	155.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,1KRZI@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH1_k127_3282390_3	1123393.KB891326_gene132	2.528e-48	176.0	COG1773@1|root,COG1773@2|Bacteria,1MV2U@1224|Proteobacteria,2VKNQ@28216|Betaproteobacteria,1KT15@119069|Hydrogenophilales	119069|Hydrogenophilales	C	HupH hydrogenase expression protein, C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HupH_C
EH1_k127_3282390_1	1123393.KB891326_gene131	3.537e-66	228.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria,1KT05@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
EH1_k127_3282390_5	1123393.KB891326_gene130	5.071e-29	118.0	COG0298@1|root,COG0298@2|Bacteria,1PWRZ@1224|Proteobacteria,2WCAT@28216|Betaproteobacteria,1KTC5@119069|Hydrogenophilales	119069|Hydrogenophilales	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH1_k127_3282390_0	543728.Vapar_1354	4.7e-76	259.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,4AFNW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
EH1_k127_3282390_6	580332.Slit_0451	6.559e-16	81.0	2CHG9@1|root,3332K@2|Bacteria,1NCD5@1224|Proteobacteria,2VWRB@28216|Betaproteobacteria,44W1I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3282390_2	522306.CAP2UW1_1027	1.53e-53	203.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
EH1_k127_328365_5	243233.MCA1380	3.898e-13	74.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XDT6@135618|Methylococcales	135618|Methylococcales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
EH1_k127_328365_1	292415.Tbd_1284	2.77e-116	383.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,1KS20@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
EH1_k127_328365_0	765913.ThidrDRAFT_1424	3.123e-137	445.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria,1WXHU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_328365_4	765910.MARPU_01555	9.521e-23	103.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1WY72@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM clan AA aspartic protease, TIGR02281 family	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
EH1_k127_328365_2	1123393.KB891327_gene481	6.027e-83	282.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria,1KSDS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
EH1_k127_328365_3	1121004.ATVC01000063_gene1634	5.802e-44	162.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,2KQ1D@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
EH1_k127_3315117_0	1123393.KB891326_gene14	1.043e-137	461.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2VMYV@28216|Betaproteobacteria,1KRYD@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3331786_2	204773.HEAR2765	2.394e-34	144.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,473BQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
EH1_k127_3331786_1	1158165.KB898875_gene94	5.112e-84	291.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
EH1_k127_3331786_0	292415.Tbd_0178	1.541e-117	383.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,1KSB0@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
EH1_k127_3332177_2	870187.Thini_2679	1.474e-78	267.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
EH1_k127_3332177_0	580332.Slit_2482	1.213e-87	306.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	1224|Proteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
EH1_k127_3332177_1	580332.Slit_2483	1.663e-80	274.0	COG4659@1|root,COG4659@2|Bacteria,1R6FE@1224|Proteobacteria,2VZVP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FMN_bind	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
EH1_k127_3335092_0	1123393.KB891316_gene1339	1.537e-135	437.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,1KRDW@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Ferrochelatase	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
EH1_k127_3335092_2	1123392.AQWL01000001_gene1437	9.032e-19	90.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C
EH1_k127_3335092_1	1123392.AQWL01000001_gene1436	6.624e-102	339.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
EH1_k127_3350340_2	1499967.BAYZ01000109_gene2982	0.0002067	53.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
EH1_k127_3350340_0	926550.CLDAP_34190	1.513e-114	380.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
EH1_k127_3350340_1	926550.CLDAP_34180	5.209e-62	226.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH1_k127_3363200_5	1123367.C666_02735	2.743e-45	167.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,2KV2R@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC1	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_3363200_3	864073.HFRIS_004803	1.721e-90	312.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,472S1@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
EH1_k127_3363200_1	1163617.SCD_n01032	3.982e-192	608.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
EH1_k127_3363200_4	159087.Daro_1279	2.048e-80	276.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,2KUWK@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
EH1_k127_3363200_0	292415.Tbd_0956	2.223e-293	908.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,1KSH9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
EH1_k127_3363200_6	265072.Mfla_1070	2.367e-37	148.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,2KN0D@206350|Nitrosomonadales	206350|Nitrosomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH1_k127_3363200_7	1288494.EBAPG3_23280	1.587e-12	71.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,373IP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
EH1_k127_3363200_2	196367.JNFG01000029_gene8630	6.317e-95	318.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,1K171@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
EH1_k127_3374017_1	1123392.AQWL01000003_gene419	1.577e-38	150.0	2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2VTMU@28216|Betaproteobacteria,1KSAH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	CNP1-like family	-	-	-	-	-	-	-	-	-	-	-	-	CNP1
EH1_k127_3374017_0	582744.Msip34_0154	3.213e-109	375.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,2KKSU@206350|Nitrosomonadales	206350|Nitrosomonadales	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
EH1_k127_3377091_0	1123393.KB891326_gene235	6.275e-146	487.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KS5V@119069|Hydrogenophilales	119069|Hydrogenophilales	L	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
EH1_k127_3378121_1	857087.Metme_3258	5.577e-74	257.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
EH1_k127_3378121_0	1123392.AQWL01000013_gene2364	3.814e-243	760.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,2VPN4@28216|Betaproteobacteria,1KSBJ@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
EH1_k127_3379819_1	1288494.EBAPG3_24400	6.736e-160	512.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,37277@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
EH1_k127_3379819_0	1049564.TevJSym_cl00010	1.253e-161	516.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1J5GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
EH1_k127_3387743_2	1266925.JHVX01000009_gene145	1.185e-112	368.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria,372DH@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Peptidase M17, leucyl aminopeptidase	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
EH1_k127_3387743_0	1131553.JIBI01000003_gene1653	6.129e-196	615.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,37234@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
EH1_k127_3387743_3	1348114.OM33_09570	2.147e-17	84.0	COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,2Q3K5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
EH1_k127_3387743_1	1123393.KB891316_gene1200	2.928e-126	413.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,1KRYG@119069|Hydrogenophilales	119069|Hydrogenophilales	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1_like
EH1_k127_3400244_0	159087.Daro_1225	3.047e-95	323.0	2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,2VPW1@28216|Betaproteobacteria,2KV1A@206389|Rhodocyclales	206389|Rhodocyclales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
EH1_k127_3400244_1	1121440.AUMA01000014_gene1935	1.425e-41	157.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,42SES@68525|delta/epsilon subdivisions,2WQ9T@28221|Deltaproteobacteria,2MC36@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
EH1_k127_3400476_2	1123517.JOMR01000001_gene934	1.311e-110	364.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1SYH6@1236|Gammaproteobacteria,463T0@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH1_k127_3400476_0	580332.Slit_1195	1.378e-161	528.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJDV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
EH1_k127_3400476_3	228410.NE1872	3.249e-110	362.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2VHYY@28216|Betaproteobacteria,371NB@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
EH1_k127_3400476_1	228410.NE1871	5.021e-136	438.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2VHYC@28216|Betaproteobacteria,371MW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
EH1_k127_3400476_4	1288494.EBAPG3_22580	3.132e-43	161.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,372GN@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
EH1_k127_3412953_1	1123393.KB891330_gene819	4.865e-94	317.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,1KSF2@119069|Hydrogenophilales	119069|Hydrogenophilales	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
EH1_k127_3412953_0	292415.Tbd_0282	1.389e-163	529.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,1KSI5@119069|Hydrogenophilales	119069|Hydrogenophilales	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR
EH1_k127_3412953_2	292415.Tbd_0281	2.226e-86	290.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
EH1_k127_3424321_2	78245.Xaut_1596	1.211e-09	60.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2TSB6@28211|Alphaproteobacteria,3F0BT@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799,ko:K18990	ko02020,map02020	M00648,M00720	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
EH1_k127_3424321_0	1304883.KI912532_gene1993	5.664e-105	350.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,2KUIM@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	HlyD_D23
EH1_k127_3424321_1	1123392.AQWL01000008_gene1184	9.47e-102	338.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,1KS6Z@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
EH1_k127_3427301_0	292415.Tbd_1757	7.208e-128	418.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,1KSVD@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
EH1_k127_3427301_2	1000565.METUNv1_00407	2.32e-75	255.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,2KWDY@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
EH1_k127_3427301_3	1123393.KB891329_gene932	4.522e-47	173.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,1KRPN@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH1_k127_3427301_4	159087.Daro_2340	1.447e-34	141.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,2KWYW@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
EH1_k127_3427301_5	1123392.AQWL01000008_gene1261	2.581e-12	72.0	29460@1|root,2ZRKG@2|Bacteria,1PBM2@1224|Proteobacteria,2W5WD@28216|Betaproteobacteria,1KTE9@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	-
EH1_k127_3427301_1	1304883.KI912532_gene2521	6.647e-127	412.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
EH1_k127_3439680_1	1163617.SCD_n00482	1.567e-107	357.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,2VZP7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
EH1_k127_3439680_3	243233.MCA0659	2.686e-20	94.0	COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,1SJ0H@1236|Gammaproteobacteria,1XFAC@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
EH1_k127_3439680_0	292415.Tbd_2035	8.278e-124	410.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
EH1_k127_3439680_2	395495.Lcho_2507	1.292e-22	98.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,1KJ7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
EH1_k127_3446773_8	1000565.METUNv1_00626	2.806e-31	132.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma E regulatory protein, MucB RseB	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
EH1_k127_3446773_9	292415.Tbd_2092	8.082e-12	76.0	COG3086@1|root,COG3086@2|Bacteria	2|Bacteria	T	response to oxidative stress	rseC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
EH1_k127_3446773_1	323848.Nmul_A1749	2.132e-155	504.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,3720B@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
EH1_k127_3446773_0	292415.Tbd_2089	2.08e-322	994.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,1KRFE@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
EH1_k127_3446773_3	1123392.AQWL01000001_gene1391	5.373e-116	379.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KRH1@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
EH1_k127_3446773_10	1177154.Y5S_02834	5.453e-10	64.0	COG4969@1|root,COG4969@2|Bacteria,1N94F@1224|Proteobacteria,1SD4U@1236|Gammaproteobacteria,1XM43@135619|Oceanospirillales	135619|Oceanospirillales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
EH1_k127_3446773_6	1121035.AUCH01000001_gene1914	2.463e-75	260.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,2KW7B@206389|Rhodocyclales	206389|Rhodocyclales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
EH1_k127_3446773_4	1163617.SCD_n01400	4.872e-107	363.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
EH1_k127_3446773_7	1163617.SCD_n01407	7.76e-64	226.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
EH1_k127_3446773_5	1123393.KB891316_gene1390	1.59e-105	348.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KS6M@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Pyridoxal phosphate biosynthesis protein PdxJ	-	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
EH1_k127_3446773_2	1123392.AQWL01000004_gene2758	2.239e-133	443.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,1KSY8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3459114_0	640081.Dsui_1963	4.734e-123	407.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KUJG@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
EH1_k127_3459114_1	1266925.JHVX01000003_gene628	8.636e-47	170.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,373C7@32003|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH1_k127_3459114_2	760117.JN27_05300	1.019e-45	168.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,474HH@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
EH1_k127_3459114_3	153948.NAL212_1571	2.288e-44	167.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2VNUH@28216|Betaproteobacteria,373XH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
EH1_k127_3467048_2	640081.Dsui_1414	3.411e-79	266.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,2KV26@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_3467048_0	1123392.AQWL01000008_gene1201	1.14e-202	640.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,1KS1T@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
EH1_k127_3467048_1	292415.Tbd_1890	6.593e-107	351.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,1KRDJ@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
EH1_k127_3467048_3	1000565.METUNv1_02426	1.956e-63	219.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
EH1_k127_3478454_0	1244869.H261_08518	1.37e-140	457.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2TSPP@28211|Alphaproteobacteria,2JQQJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
EH1_k127_3478454_1	582744.Msip34_0855	1.924e-73	254.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,2KM3S@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
EH1_k127_3495784_2	765910.MARPU_14055	5.773e-55	203.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1WXUX@135613|Chromatiales	135613|Chromatiales	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
EH1_k127_3495784_3	748247.AZKH_4606	7.11e-08	58.0	COG2703@1|root,COG2703@2|Bacteria,1P42M@1224|Proteobacteria,2W6C4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	oxygen carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3495784_1	292415.Tbd_0082	2.146e-84	289.0	COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,2VVPY@28216|Betaproteobacteria,1KSG3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
EH1_k127_3495784_0	292415.Tbd_2500	3.624e-111	363.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KRBC@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH1_k127_3500423_3	1485544.JQKP01000015_gene2058	3.871e-34	134.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,44VNW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
EH1_k127_3500423_0	1217718.ALOU01000097_gene4928	6.471e-105	346.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,1K1E9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH1_k127_3500423_2	1163617.SCD_n01525	1.48e-40	164.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM Type IV pilus assembly PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
EH1_k127_3500423_1	1038869.AXAN01000023_gene1841	2.839e-67	239.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,1K0JG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
EH1_k127_3504297_0	261292.Nit79A3_0927	1.828e-103	343.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria,372GE@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH1_k127_3504297_1	395494.Galf_1025	1.039e-86	293.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,44W6N@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	CheD chemotactic sensory transduction	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
EH1_k127_3504297_2	375286.mma_2091	9.923e-36	136.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,473JU@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH1_k127_3526909_0	1049564.TevJSym_aj00120	9.156e-128	423.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S6AN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	phosphohydrolase	rela3	-	-	-	-	-	-	-	-	-	-	-	HD_4
EH1_k127_3526909_1	1123392.AQWL01000003_gene449	1.219e-86	309.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
EH1_k127_3526909_2	1430440.MGMSRv2_0282	4.26e-53	199.0	COG2199@1|root,COG2199@2|Bacteria,1RDMU@1224|Proteobacteria,2US0M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH1_k127_3530889_0	1123393.KB891329_gene948	3.161e-145	479.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF1631,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_4
EH1_k127_3549290_0	1123393.KB891327_gene322	6.896e-290	899.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,1KSD8@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Polyphosphate kinase middle domain	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
EH1_k127_3549290_1	153948.NAL212_2861	2.542e-124	415.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,372SC@32003|Nitrosomonadales	28216|Betaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
EH1_k127_3549290_2	265072.Mfla_1912	9.996e-30	121.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,2KMQR@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
EH1_k127_3555323_1	1511.CLOST_2435	2.272e-85	308.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1UCKT@1239|Firmicutes,24GBZ@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
EH1_k127_3555323_0	1238182.C882_2606	1.343e-171	554.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,2TZMH@28211|Alphaproteobacteria,2JZ65@204441|Rhodospirillales	204441|Rhodospirillales	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,Response_reg
EH1_k127_3555323_2	1123392.AQWL01000004_gene2682	1.331e-58	211.0	COG0457@1|root,COG0457@2|Bacteria,1PXVW@1224|Proteobacteria,2WD6S@28216|Betaproteobacteria,1KSSP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_8
EH1_k127_3555323_3	159087.Daro_0355	4.888e-32	126.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,2KWF2@206389|Rhodocyclales	206389|Rhodocyclales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
EH1_k127_3565607_2	292415.Tbd_1837	1.316e-08	55.0	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,2VTZ3@28216|Betaproteobacteria,1KT83@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
EH1_k127_3565607_1	519989.ECTPHS_06202	6.73e-115	380.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
EH1_k127_3565607_0	395494.Galf_1411	7.194e-312	960.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
EH1_k127_3579468_2	1163617.SCD_n01697	1.364e-12	68.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
EH1_k127_3579468_1	292415.Tbd_1629	1.549e-56	208.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,1KRXQ@119069|Hydrogenophilales	119069|Hydrogenophilales	MNOU	Rod binding protein	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
EH1_k127_3579468_0	1122951.ATUE01000006_gene1090	3.242e-88	310.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH1_k127_3598546_2	1123393.KB891327_gene425	1.044e-32	129.0	COG2204@1|root,COG2204@2|Bacteria,1QVPI@1224|Proteobacteria,2WHXV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16
EH1_k127_3598546_0	292415.Tbd_1568	0.0	1075.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1KRI7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
EH1_k127_3598546_1	1485544.JQKP01000003_gene233	2.217e-100	330.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,44VPA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_3600960_5	765911.Thivi_3660	1.488e-34	134.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1WXIH@135613|Chromatiales	135613|Chromatiales	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
EH1_k127_3600960_0	765911.Thivi_3659	1.772e-188	599.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
EH1_k127_3600960_3	1458357.BG58_28305	1.639e-94	324.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
EH1_k127_3600960_2	1458357.BG58_28310	4.899e-100	338.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2VKSZ@28216|Betaproteobacteria,1K5PF@119060|Burkholderiaceae	28216|Betaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
EH1_k127_3600960_8	381666.H16_A2157	4.33e-23	107.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K7R1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
EH1_k127_3600960_1	1232410.KI421426_gene1474	1.256e-157	514.0	COG3264@1|root,COG3264@2|Bacteria,1QUDC@1224|Proteobacteria,43DHA@68525|delta/epsilon subdivisions,2X8P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH1_k127_3600960_7	670307.HYPDE_38268	5.892e-30	132.0	COG2207@1|root,COG2207@2|Bacteria,1P3X1@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
EH1_k127_3600960_6	314278.NB231_07442	5.303e-33	134.0	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3600960_4	247490.KSU1_C1438	8.364e-49	181.0	29MQ2@1|root,308MT@2|Bacteria,2J179@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3609153_4	316055.RPE_1227	2.61e-40	155.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,2U9I3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
EH1_k127_3609153_3	1123393.KB891317_gene2205	5.059e-42	161.0	2CB73@1|root,32RST@2|Bacteria,1MZWF@1224|Proteobacteria,2VV2C@28216|Betaproteobacteria,1KSSX@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3609153_0	243233.MCA0074	7.25e-76	260.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,1XFAZ@135618|Methylococcales	135618|Methylococcales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
EH1_k127_3609153_1	62928.azo0042	3.863e-72	254.0	COG5400@1|root,COG5400@2|Bacteria,1RASG@1224|Proteobacteria,2W1ZW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1134)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1134
EH1_k127_3609153_2	1123368.AUIS01000044_gene16	5.434e-46	173.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S7ZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	Z012_08985	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
EH1_k127_3609521_2	1163617.SCD_n01767	5.435e-53	199.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
EH1_k127_3609521_3	1121004.ATVC01000034_gene2252	1.471e-11	65.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3609521_4	981223.AIED01000149_gene464	2.742e-07	54.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3609521_0	1349767.GJA_2392	0.0	1224.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,473C8@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
EH1_k127_3609521_1	1123392.AQWL01000008_gene1181	8.626e-58	203.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KRGT@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
EH1_k127_3611981_0	1123393.KB891327_gene369	8.289e-202	645.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,1KRIN@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH1_k127_3611981_1	1123393.KB891326_gene170	1.607e-106	351.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1KRFF@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Pterin binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
EH1_k127_3611981_2	497321.C664_02740	6.019e-88	293.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
EH1_k127_3612233_0	1163617.SCD_n00989	2.366e-126	409.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	abc transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH1_k127_3612233_1	292415.Tbd_1305	1.206e-97	330.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
EH1_k127_3612233_2	1123368.AUIS01000001_gene1908	5.498e-10	63.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3618167_0	637390.AFOH01000082_gene2530	9.055e-11	70.0	COG3266@1|root,COG3266@2|Bacteria,1NQBT@1224|Proteobacteria,1SV4D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
EH1_k127_3618310_0	640081.Dsui_2420	1.835e-234	735.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
EH1_k127_3618310_1	1123392.AQWL01000004_gene2631	1.423e-81	278.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,1KRZK@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
EH1_k127_3619294_2	396588.Tgr7_0028	1.476e-47	179.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales	135613|Chromatiales	H	Uroporphyrinogen III synthase	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
EH1_k127_3619294_1	640081.Dsui_1600	7.198e-68	246.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,2KW9U@206389|Rhodocyclales	206389|Rhodocyclales	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
EH1_k127_3619294_4	62928.azo0996	3.202e-18	91.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,2KVAI@206389|Rhodocyclales	206389|Rhodocyclales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
EH1_k127_3619294_0	1123392.AQWL01000006_gene692	7.774e-149	479.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KRC9@119069|Hydrogenophilales	119069|Hydrogenophilales	CH	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
EH1_k127_3619294_3	391038.Bphy_0597	9.148e-19	87.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,1K0SV@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
EH1_k127_3621014_1	1485544.JQKP01000002_gene1464	9.487e-116	379.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS,PAS_4,dCache_3
EH1_k127_3621014_0	292415.Tbd_1078	2.77e-263	824.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,1KRBU@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
EH1_k127_3621014_2	1123393.KB891327_gene427	2.824e-36	140.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria,1KTBC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3625038_1	1144319.PMI16_03594	1.239e-08	64.0	COG2867@1|root,COG2867@2|Bacteria,1QUZA@1224|Proteobacteria,2VUHS@28216|Betaproteobacteria,4750S@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH1_k127_3625038_0	305700.B447_14144	1.934e-129	436.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria,2KXTR@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH1_k127_3645198_2	1387312.BAUS01000002_gene987	1.652e-45	167.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales	206350|Nitrosomonadales	CI	TIGRFAM oxaloacetate decarboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
EH1_k127_3645198_1	1123392.AQWL01000007_gene908	1.299e-79	270.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KSDR@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH1_k127_3645198_0	159087.Daro_2010	4.036e-84	291.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,2KW5K@206389|Rhodocyclales	206389|Rhodocyclales	H	Uroporphyrin-III C tetrapyrrole	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
EH1_k127_3647645_0	1163617.SCD_n02380	1.855e-225	707.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polyphosphate kinase	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
EH1_k127_3647645_1	743836.AYNA01000111_gene18	4.902e-33	134.0	2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,370RI@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
EH1_k127_3647645_2	338963.Pcar_2627	2.472e-26	113.0	2EHUK@1|root,33BK8@2|Bacteria,1Q1PA@1224|Proteobacteria,437D9@68525|delta/epsilon subdivisions,2X2JB@28221|Deltaproteobacteria,43VPA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3649988_4	640081.Dsui_3060	8.889e-23	100.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
EH1_k127_3649988_3	243365.CV_3799	1.647e-30	123.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,2KRJV@206351|Neisseriales	206351|Neisseriales	J	RNA-binding protein, YhbY family	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
EH1_k127_3649988_2	1163617.SCD_n00921	2.344e-52	188.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
EH1_k127_3649988_1	1123392.AQWL01000003_gene409	4.786e-74	251.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,1KRJV@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH1_k127_3649988_0	292415.Tbd_1128	0.0	1756.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,1KSTH@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
EH1_k127_3670947_1	1123393.KB891317_gene2337	1.428e-87	293.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria,1KS78@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
EH1_k127_3670947_0	1163617.SCD_n00049	1.849e-278	875.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH1_k127_3670947_2	748247.AZKH_1017	9.989e-74	254.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KW1M@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
EH1_k127_3670947_3	870187.Thini_3070	2.919e-53	188.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,4609Z@72273|Thiotrichales	72273|Thiotrichales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
EH1_k127_3672490_3	1123393.KB891329_gene1041	2.977e-09	67.0	COG3439@1|root,COG3439@2|Bacteria,1Q7MF@1224|Proteobacteria,2WBHI@28216|Betaproteobacteria,1KRXN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH1_k127_3672490_0	1123392.AQWL01000009_gene1089	0.0	1387.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1KS32@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
EH1_k127_3672490_2	292415.Tbd_1181	1.538e-31	143.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,1KRZT@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
EH1_k127_3672490_1	323848.Nmul_A2462	5.9e-35	138.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,372KP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Lactonase,Rhomboid
EH1_k127_3682339_2	640081.Dsui_2707	8.521e-35	139.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,2KYRE@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH1_k127_3682339_1	1163617.SCD_n01675	8.548e-50	180.0	COG0346@1|root,COG0346@2|Bacteria,1PVYI@1224|Proteobacteria,2VVCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH1_k127_3682339_0	1123393.KB891326_gene237	7.788e-93	310.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria,1KSW2@119069|Hydrogenophilales	119069|Hydrogenophilales	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
EH1_k127_3693564_0	62928.azo0095	0.0	1164.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
EH1_k127_3693564_2	305700.B447_05650	3.703e-32	132.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,2KWJJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
EH1_k127_3693564_1	292415.Tbd_0012	1.653e-40	153.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KRGG@119069|Hydrogenophilales	119069|Hydrogenophilales	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
EH1_k127_370687_3	580332.Slit_0561	2.55e-19	90.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria,44VS7@713636|Nitrosomonadales	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB1	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH1_k127_370687_0	1163617.SCD_n00828	9.352e-67	247.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,2VSBD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_370687_2	1123393.KB891316_gene1426	2.275e-56	200.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria,1KT3T@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_370687_1	1123392.AQWL01000001_gene1361	4.036e-59	217.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria,1KS9C@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH1_k127_370687_4	1163617.SCD_n00831	4.146e-09	64.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,2W1FP@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_3713319_2	1144275.COCOR_06852	3.484e-15	84.0	COG0586@1|root,COG0586@2|Bacteria,1QX8D@1224|Proteobacteria,43C1E@68525|delta/epsilon subdivisions,2X7C2@28221|Deltaproteobacteria,2Z3F8@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
EH1_k127_3713319_1	864051.BurJ1DRAFT_1464	1.236e-73	262.0	28JEH@1|root,2Z98N@2|Bacteria,1RIK2@1224|Proteobacteria,2VWXE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3713319_0	1317118.ATO8_16900	2.64e-158	502.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,2TUE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TatD related DNase	-	-	-	-	-	-	-	-	-	-	-	-	TatD_DNase
EH1_k127_3719793_0	580332.Slit_0621	2.257e-68	237.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,44UZ9@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH1_k127_3719793_2	1163617.SCD_n01704	1.945e-36	142.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2VUJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
EH1_k127_3719793_1	1304883.KI912532_gene157	5.685e-48	175.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2VSK1@28216|Betaproteobacteria,2KWN2@206389|Rhodocyclales	206389|Rhodocyclales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH1_k127_3719793_3	1236959.BAMT01000001_gene1057	3.018e-11	65.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria,2KMM2@206350|Nitrosomonadales	206350|Nitrosomonadales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
EH1_k127_3723269_0	1163617.SCD_n02131	9.577e-161	509.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
EH1_k127_3723269_1	1123393.KB891316_gene1141	4.169e-112	369.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,1KRIH@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
EH1_k127_3723269_2	292415.Tbd_1855	3.729e-56	199.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KS1V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
EH1_k127_3735623_0	426114.THI_0135	1.229e-240	744.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
EH1_k127_3735623_1	1123392.AQWL01000006_gene622	4.136e-148	481.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KS2E@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH1_k127_3735623_3	76114.ebA3508	3.409e-91	305.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VP8T@28216|Betaproteobacteria,2KUS8@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH1_k127_3735623_2	305700.B447_02051	2.986e-145	474.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KUGD@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3850 Signal transduction histidine kinase, nitrate nitrite-specific	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
EH1_k127_3756146_1	159087.Daro_0463	2.613e-113	389.0	COG4389@1|root,COG4389@2|Bacteria,1MWEH@1224|Proteobacteria,2VIZV@28216|Betaproteobacteria,2KUTK@206389|Rhodocyclales	206389|Rhodocyclales	L	Site-specific recombinase	-	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
EH1_k127_3756146_0	472759.Nhal_1519	4.663e-128	423.0	COG2267@1|root,COG2267@2|Bacteria,1MX2H@1224|Proteobacteria,1RRSX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	serine threonine protein kinase	IV02_22745	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3756146_2	472759.Nhal_1518	8.153e-74	256.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1WW1D@135613|Chromatiales	135613|Chromatiales	M	PFAM VacJ family lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
EH1_k127_3768801_2	426114.THI_0870	4.124e-44	173.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,1KM5R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH1_k127_3768801_0	1123393.KB891330_gene883	6.051e-252	798.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KSIC@119069|Hydrogenophilales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
EH1_k127_3768801_1	1123393.KB891330_gene884	2.592e-65	227.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,2WGI2@28216|Betaproteobacteria	28216|Betaproteobacteria	EI	urea carboxylase	uca	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
EH1_k127_3774106_3	1095769.CAHF01000014_gene2905	8.688e-31	131.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,4731B@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
EH1_k127_3774106_1	1485544.JQKP01000002_gene1623	2.669e-141	453.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
EH1_k127_3774106_2	292415.Tbd_0121	1.351e-110	367.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
EH1_k127_3774106_0	582744.Msip34_0461	2.057e-148	475.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,2KMBW@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_3780295_1	1288494.EBAPG3_18310	3.498e-78	271.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,3721F@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
EH1_k127_3780295_0	1163617.SCD_n00013	5.133e-199	642.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
EH1_k127_3780295_2	243365.CV_4261	9.083e-11	64.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,2KR2I@206351|Neisseriales	206351|Neisseriales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
EH1_k127_3780308_1	768671.ThimaDRAFT_4419	2.712e-304	946.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WWTA@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_3780308_2	1163617.SCD_n02265	1.859e-47	177.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Nitrite reductase NAD(P)H , small subunit	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
EH1_k127_3780308_0	1163617.SCD_n02264	0.0	1301.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	nitrite reductase NAD(P)H	nasD	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
EH1_k127_3780762_2	580332.Slit_2362	4.667e-56	199.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,44VE9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
EH1_k127_3780762_5	582744.Msip34_1996	8.594e-37	141.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KKJN@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
EH1_k127_3780762_0	582744.Msip34_1996	3.213e-201	640.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KKJN@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
EH1_k127_3780762_4	1123392.AQWL01000002_gene2115	3.254e-43	158.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,1KRT0@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
EH1_k127_3780762_1	228410.NE0968	1.626e-62	219.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,37305@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
EH1_k127_3780762_3	1123392.AQWL01000002_gene2113	2.756e-54	196.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,1KRP7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
EH1_k127_3780762_6	62928.azo0764	1.594e-28	116.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,2KV10@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH1_k127_3820022_2	1123487.KB892841_gene4319	1.335e-17	91.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,2KWMY@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
EH1_k127_3820022_1	292415.Tbd_0592	4.588e-63	233.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,1KRTF@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Tetratricopeptide repeat	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_8
EH1_k127_3820022_0	1163617.SCD_n01812	2.511e-177	562.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
EH1_k127_3833725_1	305700.B447_07614	7.803e-111	371.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
EH1_k127_3833725_0	1123393.KB891316_gene1835	0.0	1028.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria,1KRXT@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
EH1_k127_3838058_1	1123392.AQWL01000004_gene2493	2.073e-66	231.0	29C3U@1|root,2ZZ29@2|Bacteria,1RFDP@1224|Proteobacteria,2VS91@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3838058_3	768671.ThimaDRAFT_1865	1.681e-64	227.0	2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria,1SRBB@1236|Gammaproteobacteria,1X1A2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3838058_2	768671.ThimaDRAFT_1866	3.08e-65	228.0	COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,1X0YX@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_3838058_0	1123392.AQWL01000001_gene1598	2.677e-119	397.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2W1SC@28216|Betaproteobacteria,1KSI9@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
EH1_k127_3842698_0	74547.PMT_1557	1.293e-71	262.0	COG0493@1|root,COG1233@1|root,COG0493@2|Bacteria,COG1233@2|Bacteria,1GPBW@1117|Cyanobacteria,1MPBT@1212|Prochloraceae	1117|Cyanobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
EH1_k127_3843193_0	1121861.KB899911_gene1186	5.383e-149	499.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	28211|Alphaproteobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH1_k127_3843193_2	1218075.BAYA01000015_gene4273	7.135e-56	224.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
EH1_k127_3843193_1	864702.OsccyDRAFT_2446	2.093e-57	220.0	COG0457@1|root,COG2520@1|root,COG0457@2|Bacteria,COG2520@2|Bacteria,1G193@1117|Cyanobacteria,1HE9A@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_8
EH1_k127_3846542_0	292415.Tbd_2414	1.519e-216	688.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,1KRAA@119069|Hydrogenophilales	119069|Hydrogenophilales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
EH1_k127_3846542_3	1304883.KI912532_gene956	8.36e-33	130.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphotransferase System	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
EH1_k127_3846542_2	1236959.BAMT01000006_gene336	1.948e-40	156.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,2KMX4@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
EH1_k127_3846542_1	1485544.JQKP01000002_gene1360	1.596e-164	526.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH1_k127_3846641_2	76114.ebA6835	1.327e-15	79.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,2KVFH@206389|Rhodocyclales	206389|Rhodocyclales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
EH1_k127_3846641_0	261292.Nit79A3_1229	3.958e-124	404.0	COG3568@1|root,COG3568@2|Bacteria,1R99W@1224|Proteobacteria,2VPVB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH1_k127_3846641_1	1496688.ER33_11275	1.787e-16	80.0	COG4943@1|root,COG4943@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	CSS-motif,EAL
EH1_k127_38578_1	1485544.JQKP01000003_gene125	5.608e-84	281.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,44VS0@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
EH1_k127_38578_2	1123393.KB891316_gene1419	2.361e-67	243.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VT0X@28216|Betaproteobacteria,1KSZ1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
EH1_k127_38578_0	864073.HFRIS_013805	7.523e-111	375.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,475S0@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
EH1_k127_3871528_1	85643.Tmz1t_3867	8.664e-43	162.0	COG3713@1|root,COG3713@2|Bacteria,1N0BC@1224|Proteobacteria,2WAUT@28216|Betaproteobacteria,2KZMR@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
EH1_k127_3871528_2	765911.Thivi_4360	1.585e-22	105.0	28K7D@1|root,2Z9VI@2|Bacteria,1R8BZ@1224|Proteobacteria,1S0U2@1236|Gammaproteobacteria,1WXW5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3876826_2	292415.Tbd_0896	1.445e-116	381.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,1KRIJ@119069|Hydrogenophilales	119069|Hydrogenophilales	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
EH1_k127_3876826_0	62928.azo1497	2.885e-172	557.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,2KUA1@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH1_k127_3876826_1	261292.Nit79A3_0196	1.255e-130	434.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,371ZG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
EH1_k127_3876826_3	1163617.SCD_n00786	1.849e-31	125.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
EH1_k127_3879826_1	292415.Tbd_1137	5.549e-73	250.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KS4M@119069|Hydrogenophilales	119069|Hydrogenophilales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH1_k127_3879826_0	292415.Tbd_1420	4.25e-175	553.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1KSC1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
EH1_k127_3879826_2	748247.AZKH_3753	4.456e-38	146.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,2KU7J@206389|Rhodocyclales	206389|Rhodocyclales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
EH1_k127_3884039_0	640081.Dsui_1710	1.642e-170	557.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH1_k127_3884039_2	228410.NE1865	3.102e-65	226.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,3734B@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	PFAM CheW-like protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH1_k127_3884039_1	1485544.JQKP01000011_gene701	5.306e-154	492.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,44W69@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
EH1_k127_3885872_4	323848.Nmul_A0792	1.94e-135	436.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,372HG@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
EH1_k127_3885872_8	1051985.l11_00530	1.173e-55	196.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,2KR2K@206351|Neisseriales	206351|Neisseriales	J	ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
EH1_k127_3885872_7	522306.CAP2UW1_3654	1.029e-71	250.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2VQJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
EH1_k127_3885872_5	292415.Tbd_0433	1.333e-126	418.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	hydroxypyruvate reductase	ttuD2	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
EH1_k127_3885872_1	1123487.KB892857_gene2452	3.309e-200	644.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	rpfC	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
EH1_k127_3885872_2	1123487.KB892857_gene2451	1.678e-154	499.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,2VK22@28216|Betaproteobacteria,2KW00@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
EH1_k127_3885872_6	1123392.AQWL01000018_gene68	4.835e-120	389.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,1KRXP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,S4
EH1_k127_3885872_0	314345.SPV1_04928	0.0	1388.0	28HY3@1|root,2Z83I@2|Bacteria,1R5P3@1224|Proteobacteria	1224|Proteobacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
EH1_k127_3885872_3	1121035.AUCH01000009_gene894	5.702e-146	468.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,2KVHH@206389|Rhodocyclales	206389|Rhodocyclales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH1_k127_3899252_1	1120999.JONM01000005_gene3777	3.788e-112	368.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,2KPJY@206351|Neisseriales	206351|Neisseriales	KL	ATP-dependent DNA helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2
EH1_k127_3899252_2	1123392.AQWL01000011_gene2223	2.141e-68	242.0	COG1073@1|root,COG1073@2|Bacteria,1RD2N@1224|Proteobacteria,2W2I1@28216|Betaproteobacteria,1KS8X@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF1749)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3899252_0	1123392.AQWL01000011_gene2224	2.7e-159	528.0	COG5001@1|root,COG5001@2|Bacteria,1R59J@1224|Proteobacteria,2W00Q@28216|Betaproteobacteria,1KSEW@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH1_k127_3899252_3	1095769.CAHF01000011_gene2339	1.876e-29	130.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,2VM4I@28216|Betaproteobacteria,474CS@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
EH1_k127_3927849_1	1123392.AQWL01000018_gene70	7.031e-154	494.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,1KRDC@119069|Hydrogenophilales	119069|Hydrogenophilales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
EH1_k127_3927849_4	1123392.AQWL01000012_gene2472	2.778e-57	205.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1KS1D@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
EH1_k127_3927849_5	395494.Galf_1389	5.519e-46	178.0	COG5380@1|root,COG5380@2|Bacteria	2|Bacteria	O	lipid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_chap
EH1_k127_3927849_0	62928.azo0150	2.199e-186	596.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
EH1_k127_3927849_6	1123392.AQWL01000018_gene73	1.285e-34	133.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,1KTCQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
EH1_k127_3927849_3	1123392.AQWL01000018_gene74	9.35e-85	285.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,1KRNY@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
EH1_k127_3927849_2	1123392.AQWL01000018_gene75	2.875e-153	486.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,1KRHM@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
EH1_k127_3927993_3	1163617.SCD_n00064	3.047e-20	91.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH1_k127_3927993_0	497321.C664_15588	2.1e-127	417.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,2KUFV@206389|Rhodocyclales	206389|Rhodocyclales	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
EH1_k127_3927993_1	1123392.AQWL01000004_gene2561	5.591e-117	384.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,1KSQZ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3927993_4	1502852.FG94_00641	8.725e-12	74.0	COG1570@1|root,COG1570@2|Bacteria,1QWH2@1224|Proteobacteria,2WGZR@28216|Betaproteobacteria,474TG@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH1_k127_3927993_2	1163617.SCD_n02515	3.725e-22	99.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH1_k127_3928272_1	1163617.SCD_n00688	4.894e-68	232.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Isocitrate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
EH1_k127_3928272_3	883126.HMPREF9710_00329	1.14e-30	126.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474WK@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH1_k127_3928272_2	76114.ebD83	2.363e-33	138.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,2KWPQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
EH1_k127_3928272_0	1000565.METUNv1_01872	0.0	1174.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KUE7@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH1_k127_3937542_1	292415.Tbd_0620	1.074e-134	430.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KRZE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
EH1_k127_3937542_0	1123393.KB891328_gene662	4.889e-220	688.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,1KSF7@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
EH1_k127_3937542_2	1120999.JONM01000012_gene2279	1.509e-09	59.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,2KRMR@206351|Neisseriales	206351|Neisseriales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
EH1_k127_3938954_3	305700.B447_03613	1.749e-73	258.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,2KVTG@206389|Rhodocyclales	206389|Rhodocyclales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
EH1_k127_3938954_2	1121035.AUCH01000017_gene2248	8.938e-162	514.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
EH1_k127_3938954_6	292415.Tbd_1000	2.755e-48	179.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,1KTBK@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Small MutS-related domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
EH1_k127_3938954_5	1304883.KI912532_gene2517	2.901e-61	223.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,2KWDI@206389|Rhodocyclales	206389|Rhodocyclales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH1_k127_3938954_4	497321.C664_01800	4.111e-64	231.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,2KW90@206389|Rhodocyclales	206389|Rhodocyclales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
EH1_k127_3938954_7	1415780.JPOG01000001_gene876	2.838e-26	111.0	COG2916@1|root,COG2916@2|Bacteria,1N7YA@1224|Proteobacteria,1SFZZ@1236|Gammaproteobacteria,1X88J@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain in histone-like proteins of HNS family	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
EH1_k127_3938954_0	335283.Neut_0860	3.5e-323	1016.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,371W3@32003|Nitrosomonadales	28216|Betaproteobacteria	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
EH1_k127_3938954_1	265072.Mfla_0061	1.06e-220	691.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KM12@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH1_k127_3938954_8	1268237.G114_01954	0.0004845	45.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1Y4S3@135624|Aeromonadales	135624|Aeromonadales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
EH1_k127_3951069_1	1123392.AQWL01000006_gene564	4.475e-61	216.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KSQG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
EH1_k127_3951069_2	1123392.AQWL01000002_gene1877	5.062e-53	190.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,2VX7W@28216|Betaproteobacteria,1KT27@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3951069_3	1123392.AQWL01000002_gene1876	4.769e-20	92.0	2AG05@1|root,31646@2|Bacteria,1PWTJ@1224|Proteobacteria,2WCCA@28216|Betaproteobacteria,1KTET@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3951069_0	292415.Tbd_0131	3.533e-320	993.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KS70@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH1_k127_3955684_4	1288494.EBAPG3_30050	1.379e-65	228.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,371ZR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
EH1_k127_3955684_3	292415.Tbd_0428	3.269e-71	241.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,1KRMC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
EH1_k127_3955684_8	323848.Nmul_A0789	2.264e-53	189.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,37389@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
EH1_k127_3955684_13	1286106.MPL1_09717	1.103e-12	68.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,461DS@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
EH1_k127_3955684_11	626418.bglu_1g02790	1.721e-37	146.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,1K9AT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
EH1_k127_3955684_0	292415.Tbd_0425	1.757e-241	751.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,1KRD8@119069|Hydrogenophilales	119069|Hydrogenophilales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
EH1_k127_3955684_7	580332.Slit_0786	6.399e-55	198.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
EH1_k127_3955684_12	1454004.AW11_00702	5.015e-21	93.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,1KQ4Y@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
EH1_k127_3955684_1	1123393.KB891318_gene2151	1.233e-81	274.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,1KRKS@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
EH1_k127_3955684_9	522306.CAP2UW1_3477	1.726e-46	169.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,1KQ25@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
EH1_k127_3955684_2	305700.B447_16031	2.705e-74	253.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KW6K@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
EH1_k127_3955684_5	987059.RBXJA2T_02190	1.876e-61	213.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1KKUW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
EH1_k127_3955684_10	1123487.KB892835_gene3654	1.103e-42	159.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,2KX1F@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
EH1_k127_3955684_6	1163617.SCD_n00637	8.903e-60	207.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
EH1_k127_3969179_3	1123354.AUDR01000018_gene1123	4.579e-23	105.0	2E6EI@1|root,33120@2|Bacteria,1NA6C@1224|Proteobacteria,2VW1M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_3969179_1	1123392.AQWL01000018_gene78	2.819e-105	356.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,1KSM5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH1_k127_3969179_0	1123367.C666_12820	5.854e-128	420.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,2KUFP@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
EH1_k127_3969179_2	640081.Dsui_0993	2.25e-81	277.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
EH1_k127_399127_2	1123393.KB891316_gene2079	7.548e-153	489.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,1KRDE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH1_k127_399127_3	159087.Daro_4088	3.005e-126	414.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,2KVXE@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH1_k127_399127_0	1123393.KB891330_gene892	2.783e-170	544.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2VSIQ@28216|Betaproteobacteria,1KRWA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
EH1_k127_399127_1	159087.Daro_0080	1.125e-163	522.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VMK8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
EH1_k127_3994345_3	754476.Q7A_2256	5.385e-24	104.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,461AY@72273|Thiotrichales	72273|Thiotrichales	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
EH1_k127_3994345_0	522306.CAP2UW1_1003	1.624e-275	856.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KR73@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
EH1_k127_3994345_1	640081.Dsui_3034	2.28e-198	626.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KUCG@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC
EH1_k127_3994345_2	1123393.KB891316_gene1774	8.127e-130	417.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KRN6@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH1_k127_3997562_1	187272.Mlg_0689	8.749e-36	139.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WW1B@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH1_k127_3997562_0	1121035.AUCH01000026_gene3371	1.942e-216	685.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,2KV1E@206389|Rhodocyclales	206389|Rhodocyclales	O	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
EH1_k127_4002574_0	292415.Tbd_0198	5.461e-171	548.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c
EH1_k127_4002574_1	1123392.AQWL01000002_gene1949	7.758e-123	399.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KS92@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH1_k127_4031087_2	1000565.METUNv1_03305	3.584e-83	284.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KUUJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH1_k127_4031087_4	1120999.JONM01000004_gene3677	2.048e-61	219.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,2KR43@206351|Neisseriales	206351|Neisseriales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
EH1_k127_4031087_1	395494.Galf_0151	8.958e-118	386.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
EH1_k127_4031087_7	381666.H16_A0735	3.812e-28	115.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KA31@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
EH1_k127_4031087_3	1163617.SCD_n02926	9.473e-63	219.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH1_k127_4031087_5	640081.Dsui_0659	1.908e-52	187.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH1_k127_4031087_6	1304883.KI912532_gene1113	5.628e-31	128.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
EH1_k127_4031087_0	292415.Tbd_2549	1.563e-165	545.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,1KSV7@119069|Hydrogenophilales	119069|Hydrogenophilales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
EH1_k127_4031087_8	1454004.AW11_00424	6.033e-22	101.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH1_k127_4034342_1	756272.Plabr_3851	1.483e-57	208.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
EH1_k127_4043434_0	697282.Mettu_3446	1.487e-286	894.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1XEK9@135618|Methylococcales	135618|Methylococcales	E	Bacterial transglutaminase-like N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
EH1_k127_4043434_3	1485544.JQKP01000020_gene68	1.035e-102	340.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,44WAN@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
EH1_k127_4043434_4	1123393.KB891316_gene1616	4.275e-56	197.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2VPAX@28216|Betaproteobacteria,1KT1P@119069|Hydrogenophilales	119069|Hydrogenophilales	H	6-pyruvoyl tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
EH1_k127_4043434_2	640081.Dsui_3449	3.167e-112	378.0	COG2197@1|root,COG5001@1|root,COG2197@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9,Response_reg
EH1_k127_4043434_1	522306.CAP2UW1_4238	1.565e-169	556.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	yfgF	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
EH1_k127_4043434_6	159087.Daro_3353	2.049e-40	166.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2VR6A@28216|Betaproteobacteria,2KWI6@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
EH1_k127_4043434_7	1485544.JQKP01000003_gene120	1.141e-23	115.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_4043434_5	1123393.KB891316_gene1792	9.461e-49	175.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KRX2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH1_k127_4045093_1	1121035.AUCH01000019_gene2868	2.624e-167	533.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
EH1_k127_4045093_0	640081.Dsui_3159	5.701e-181	590.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUUR@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
EH1_k127_4045093_2	85643.Tmz1t_3400	1.689e-20	95.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,2KW5Q@206389|Rhodocyclales	206389|Rhodocyclales	K	response regulator	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
EH1_k127_406485_2	265072.Mfla_0770	3.481e-33	130.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,2KMGZ@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
EH1_k127_406485_1	265072.Mfla_0771	1.971e-151	486.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KKPF@206350|Nitrosomonadales	206350|Nitrosomonadales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
EH1_k127_406485_0	292415.Tbd_2506	7.561e-195	621.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
EH1_k127_4071043_4	1163617.SCD_n01543	3.918e-12	78.0	COG4568@1|root,COG4568@2|Bacteria,1P9SY@1224|Proteobacteria	1224|Proteobacteria	K	Modulator of Rho-dependent transcription termination (ROF)	-	-	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	-
EH1_k127_4071043_1	1123393.KB891333_gene2588	4.494e-121	398.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,1KS2H@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
EH1_k127_4071043_3	1123392.AQWL01000007_gene904	1.334e-40	156.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,1KT8D@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
EH1_k127_4071043_2	1454004.AW11_03049	3.735e-76	263.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1KQP9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH1_k127_4071043_0	323848.Nmul_A1604	2.261e-175	559.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,3720W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
EH1_k127_4095159_0	187303.BN69_1632	1.186e-09	70.0	2AD5A@1|root,312TW@2|Bacteria,1PR73@1224|Proteobacteria,2V5AS@28211|Alphaproteobacteria,370SA@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4096110_9	743720.Psefu_4190	2.374e-19	94.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,1YVCY@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	lipopolysaccharide heptosyltransferase I	rfaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iB21_1397.B21_03429,iECBD_1354.ECBD_0105,iECB_1328.ECB_03478,iECD_1391.ECD_03478,iECNA114_1301.ECNA114_3774,iECSF_1327.ECSF_3456,iSF_1195.SF3661,iS_1188.S4107	Glyco_transf_9
EH1_k127_4096110_1	76114.ebA3998	5.011e-159	508.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH1_k127_4096110_5	1245471.PCA10_52240	1.224e-65	233.0	COG0515@1|root,COG0515@2|Bacteria,1RF4R@1224|Proteobacteria,1S7ZX@1236|Gammaproteobacteria,1YG4D@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH1_k127_4096110_8	754476.Q7A_2710	1.046e-26	115.0	COG0515@1|root,COG0515@2|Bacteria,1RJDC@1224|Proteobacteria,1SBNM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH1_k127_4096110_11	1101195.Meth11DRAFT_1933	1.409e-09	70.0	COG0515@1|root,COG0515@2|Bacteria,1RI1E@1224|Proteobacteria,2WGF8@28216|Betaproteobacteria,2KP9V@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH1_k127_4096110_3	1026882.MAMP_02766	3.671e-89	299.0	COG0500@1|root,COG2226@2|Bacteria,1QXB0@1224|Proteobacteria,1T36U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
EH1_k127_4096110_4	292415.Tbd_2522	1.829e-68	243.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
EH1_k127_4096110_7	1304883.KI912532_gene1079	4.197e-58	207.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KWH7@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
EH1_k127_4096110_6	1121004.ATVC01000004_gene1494	3.001e-58	206.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KR4E@206351|Neisseriales	206351|Neisseriales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
EH1_k127_4096110_0	1163617.SCD_n02785	1.48e-252	783.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-CoA carboxylase biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH1_k127_4096110_2	1218076.BAYB01000035_gene5314	2.148e-107	355.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1K3BV@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
EH1_k127_4096110_10	159087.Daro_3936	1.341e-12	68.0	COG1273@1|root,COG1273@2|Bacteria,1QVC4@1224|Proteobacteria,2WGPK@28216|Betaproteobacteria,2KWNJ@206389|Rhodocyclales	206389|Rhodocyclales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
EH1_k127_4096257_3	1123393.KB891332_gene2766	2.378e-79	272.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KRGG@119069|Hydrogenophilales	119069|Hydrogenophilales	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
EH1_k127_4096257_2	1123393.KB891332_gene2765	1.227e-91	314.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,1KSSH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
EH1_k127_4096257_4	1502770.JQMG01000001_gene642	1.619e-70	242.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,2KMM5@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
EH1_k127_4096257_1	748247.AZKH_0057	1.933e-114	384.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KVNV@206389|Rhodocyclales	206389|Rhodocyclales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
EH1_k127_4096257_0	742159.HMPREF0004_5079	6.098e-190	599.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,3T2I4@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
EH1_k127_4097564_1	1266925.JHVX01000002_gene1077	7.9e-40	150.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,371X6@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH1_k127_4097564_0	1217718.ALOU01000027_gene3624	1.145e-76	262.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1K1T9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH1_k127_4097564_2	748247.AZKH_2843	3.704e-09	64.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,2KXA7@206389|Rhodocyclales	206389|Rhodocyclales	T	Anti sigma-E protein RseA	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
EH1_k127_4097564_3	1485544.JQKP01000010_gene787	0.0003097	51.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,44V1A@713636|Nitrosomonadales	28216|Betaproteobacteria	T	MucB/RseB C-terminal domain	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
EH1_k127_4110069_0	1163617.SCD_n01950	4.364e-171	567.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
EH1_k127_4110069_1	1163617.SCD_n01949	2.736e-136	445.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
EH1_k127_4110069_2	1236959.BAMT01000012_gene3037	1.782e-36	142.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,2KKXM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH1_k127_4130806_0	666685.R2APBS1_0489	3.231e-89	308.0	28PII@1|root,2ZC8H@2|Bacteria,1R6MG@1224|Proteobacteria,1RZZF@1236|Gammaproteobacteria,1X769@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
EH1_k127_4130806_1	1121403.AUCV01000028_gene2413	0.0007921	51.0	28U5F@1|root,2ZGBA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4141125_3	765911.Thivi_1130	1.312e-08	58.0	2EE2B@1|root,337X1@2|Bacteria,1N433@1224|Proteobacteria,1SB80@1236|Gammaproteobacteria,1WZ02@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4141125_2	85643.Tmz1t_1471	2.512e-66	232.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VRAN@28216|Betaproteobacteria,2KXE9@206389|Rhodocyclales	206389|Rhodocyclales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
EH1_k127_4141125_0	85643.Tmz1t_1472	1.334e-141	458.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2VKGU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
EH1_k127_4141125_1	85643.Tmz1t_1473	5.529e-141	455.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
EH1_k127_4155926_3	292415.Tbd_1778	3.275e-52	200.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1KRMV@119069|Hydrogenophilales	119069|Hydrogenophilales	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
EH1_k127_4155926_1	1123393.KB891316_gene1086	5.833e-165	523.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,1KRIG@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH1_k127_4155926_0	1123393.KB891316_gene1087	8.71e-216	673.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1KRJ4@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
EH1_k127_4155926_2	1121943.KB899989_gene3226	8.262e-53	187.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XH3I@135619|Oceanospirillales	135619|Oceanospirillales	M	UDP-glucose 4-epimerase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
EH1_k127_4177767_0	62928.azo2902	4.66e-71	253.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,2KUBZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH1_k127_4177767_1	395494.Galf_2523	6.956e-63	224.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,44V0Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH1_k127_4178829_0	1387312.BAUS01000002_gene812	8.564e-81	278.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KM5A@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH1_k127_4180324_3	765912.Thimo_1245	4.01e-11	68.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
EH1_k127_4180324_0	1120999.JONM01000013_gene2124	2.325e-57	217.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KQQD@206351|Neisseriales	1224|Proteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH1_k127_4180324_1	243365.CV_1666	4.032e-51	186.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,2KQ0X@206351|Neisseriales	206351|Neisseriales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_4180324_2	1235457.C404_18610	2.959e-17	84.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1K14Y@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_4184113_1	1163617.SCD_n00077	2.026e-61	216.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_4184113_3	1123368.AUIS01000005_gene398	1.568e-28	126.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,2NE49@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
EH1_k127_4184113_0	1163617.SCD_n00082	3.229e-126	419.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
EH1_k127_4184113_2	1458427.BAWN01000028_gene1605	3.961e-55	195.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,4AAM5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
EH1_k127_4190472_1	1123392.AQWL01000001_gene1455	1.311e-67	235.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,1KSUU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
EH1_k127_4190472_0	580332.Slit_2396	5.477e-78	276.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
EH1_k127_4190472_2	153948.NAL212_0201	1.5e-67	250.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,37230@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
EH1_k127_4201783_0	207559.Dde_3114	2.28e-155	505.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2WJJ9@28221|Deltaproteobacteria,2M8RX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
EH1_k127_4201783_1	1121447.JONL01000008_gene3610	1.526e-88	309.0	COG4191@1|root,COG4564@1|root,COG5000@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions,2WJVA@28221|Deltaproteobacteria,2M8BT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,NMT1,PAS_3,PAS_4,Response_reg,dCache_1,sCache_2
EH1_k127_4214166_0	1123392.AQWL01000004_gene2679	2.272e-100	342.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KSC3@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH1_k127_4214166_1	292415.Tbd_0519	8.389e-94	315.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
EH1_k127_4214166_2	292415.Tbd_2583	1.582e-06	49.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KS69@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH1_k127_4218666_0	266264.Rmet_1537	5.6e-230	724.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1K2HP@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF2	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Carbam_trans_N,Sua5_yciO_yrdC,zf-HYPF
EH1_k127_4218666_2	640081.Dsui_1160	9.639e-24	110.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,2KX70@206389|Rhodocyclales	206389|Rhodocyclales	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH1_k127_4218666_1	640081.Dsui_1159	2.924e-117	384.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,2KVMG@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
EH1_k127_4237821_3	1163617.SCD_n00989	5.531e-27	112.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	abc transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH1_k127_4237821_1	261292.Nit79A3_2344	4.59e-119	410.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2VHZ6@28216|Betaproteobacteria,371TT@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase, class I	-	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_4237821_0	443143.GM18_0084	2.538e-303	946.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
EH1_k127_4237821_2	1163617.SCD_n01865	2.081e-80	279.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
EH1_k127_4238990_7	1123392.AQWL01000003_gene138	1.792e-06	50.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,2W5RM@28216|Betaproteobacteria,1KTDI@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4238990_0	1123392.AQWL01000009_gene1107	1.026e-178	569.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1KRFZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
EH1_k127_4238990_1	62928.azo2824	1.032e-86	295.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2VIX0@28216|Betaproteobacteria,2KVCD@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
EH1_k127_4238990_6	1123392.AQWL01000006_gene543	9.754e-22	100.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2WCAE@28216|Betaproteobacteria,1KTBI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
EH1_k127_4238990_4	1123368.AUIS01000016_gene2541	1.454e-57	207.0	COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,1S328@1236|Gammaproteobacteria,2NCGK@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
EH1_k127_4238990_3	398767.Glov_0813	5.125e-59	219.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria	1224|Proteobacteria	S	peptidase m48, ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH1_k127_4238990_5	515635.Dtur_1814	1.461e-44	170.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH1_k127_4238990_2	1121035.AUCH01000022_gene3204	7.516e-84	293.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2W0B5@28216|Betaproteobacteria,2KXXD@206389|Rhodocyclales	206389|Rhodocyclales	S	Sugar fermentation stimulation protein	-	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
EH1_k127_4324916_3	757424.Hsero_0161	5.376e-39	146.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
EH1_k127_4324916_2	292415.Tbd_2399	4.473e-41	155.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1KRUK@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_4324916_4	1123392.AQWL01000005_gene3138	1.296e-22	98.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,1KRVZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
EH1_k127_4324916_0	1123368.AUIS01000003_gene1734	0.0	1461.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2NC0D@225057|Acidithiobacillales	225057|Acidithiobacillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH1_k127_4324916_1	1123368.AUIS01000003_gene1735	4.107e-78	278.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1SYRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
EH1_k127_4324916_5	1123368.AUIS01000003_gene1736	2.511e-22	99.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1RYS4@1236|Gammaproteobacteria,2NC0F@225057|Acidithiobacillales	225057|Acidithiobacillales	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_4324990_2	1123487.KB892868_gene1149	0.0001318	46.0	2C845@1|root,33NTC@2|Bacteria,1NPCK@1224|Proteobacteria,2W63X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4324990_0	404380.Gbem_1808	1.952e-148	476.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
EH1_k127_4324990_1	443144.GM21_2441	2.304e-59	209.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,43VMU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
EH1_k127_4326854_3	159087.Daro_1973	3.729e-56	199.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
EH1_k127_4326854_1	1163617.SCD_n01758	1.143e-103	343.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
EH1_k127_4326854_2	1304883.KI912532_gene2329	8.018e-65	231.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,2VRE4@28216|Betaproteobacteria,2KWM9@206389|Rhodocyclales	206389|Rhodocyclales	S	AMMECR1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
EH1_k127_4326854_0	1163617.SCD_n01760	2.553e-123	408.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
EH1_k127_4336103_9	292415.Tbd_0785	6.467e-114	376.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,1KRDB@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
EH1_k127_4336103_1	292415.Tbd_0786	7.03e-157	497.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1KRCJ@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
EH1_k127_4336103_8	1123392.AQWL01000004_gene2535	8.394e-115	374.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1KS6B@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH1_k127_4336103_12	1485544.JQKP01000007_gene1934	1.559e-80	271.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
EH1_k127_4336103_10	1144319.PMI16_00361	1.712e-113	370.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,4727W@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
EH1_k127_4336103_15	1163617.SCD_n01630	3.952e-56	208.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
EH1_k127_4336103_2	1288494.EBAPG3_760	1.447e-154	500.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,3723X@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
EH1_k127_4336103_3	265072.Mfla_1523	1.585e-132	439.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,2KKRG@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
EH1_k127_4336103_0	292415.Tbd_0793	3.558e-318	992.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,1KRHS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH1_k127_4336103_16	1163617.SCD_n01626	7.03e-52	188.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the skp family	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
EH1_k127_4336103_11	292415.Tbd_0795	5.98e-104	348.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,1KRZF@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
EH1_k127_4336103_14	580332.Slit_1640	1.267e-58	208.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,44VTF@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
EH1_k127_4336103_4	292415.Tbd_0797	6.588e-125	404.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1KRBA@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
EH1_k127_4336103_5	1163617.SCD_n01622	1.981e-123	407.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
EH1_k127_4336103_13	640081.Dsui_2680	4.087e-65	236.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,2KW1V@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
EH1_k127_4336103_6	1502770.JQMG01000001_gene1864	6.432e-122	396.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,2KKD9@206350|Nitrosomonadales	206350|Nitrosomonadales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH1_k127_4336103_7	1123393.KB891327_gene458	1.357e-120	393.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,1KR9R@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH1_k127_4337531_1	1123401.JHYQ01000035_gene3479	5.818e-145	466.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	yqeF	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSSON_1240.SSON_3004	Thiolase_C,Thiolase_N
EH1_k127_4337531_2	519989.ECTPHS_00280	4.187e-77	271.0	28KIX@1|root,2Z9Y0@2|Bacteria,1R427@1224|Proteobacteria,1RRGI@1236|Gammaproteobacteria,1WX2J@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
EH1_k127_4337531_0	870187.Thini_1526	1.042e-184	582.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,461VP@72273|Thiotrichales	72273|Thiotrichales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
EH1_k127_4357724_2	582744.Msip34_0458	3.836e-85	292.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,2KM82@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	-	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_M
EH1_k127_4357724_0	1123392.AQWL01000002_gene1861	1.186e-143	469.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,1KS5G@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
EH1_k127_4357724_1	1163617.SCD_n02485	5.232e-131	427.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
EH1_k127_4369157_1	1123393.KB891316_gene1135	6.539e-178	559.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1KRGB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH1_k127_4369157_9	1123393.KB891316_gene1134	1.493e-28	117.0	2AFYM@1|root,3162D@2|Bacteria,1PWQV@1224|Proteobacteria,2WC9G@28216|Betaproteobacteria,1KTA5@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
EH1_k127_4369157_0	1123393.KB891316_gene1133	4.332e-256	794.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KSBA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
EH1_k127_4369157_10	640081.Dsui_3247	7.732e-25	105.0	2DNMC@1|root,32Y3R@2|Bacteria,1N8DI@1224|Proteobacteria,2VVNN@28216|Betaproteobacteria,2KXCE@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2788
EH1_k127_4369157_8	640081.Dsui_3246	1.187e-51	192.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,2KWJ5@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
EH1_k127_4369157_7	1288826.MSNKSG1_17386	9.425e-77	268.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
EH1_k127_4369157_6	1120999.JONM01000006_gene2458	7.629e-87	297.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KPIX@206351|Neisseriales	206351|Neisseriales	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
EH1_k127_4369157_2	1123392.AQWL01000004_gene2842	8.526e-112	368.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KSJI@119069|Hydrogenophilales	119069|Hydrogenophilales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
EH1_k127_4369157_5	1123393.KB891328_gene515	3.029e-90	306.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KS5M@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
EH1_k127_4369157_4	626418.bglu_1g08280	2.79e-106	349.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,1K0EK@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
EH1_k127_4369157_3	1123393.KB891328_gene517	1.773e-106	350.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1KRM5@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
EH1_k127_4393476_0	522306.CAP2UW1_2484	1.571e-107	379.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1RDHW@1224|Proteobacteria,2VRY7@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,Trypsin_2
EH1_k127_4393476_1	522306.CAP2UW1_2485	4.234e-56	208.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1RHVK@1224|Proteobacteria,2VT8V@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_8,Trypsin_2
EH1_k127_4398996_1	292415.Tbd_1855	7.931e-82	277.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KS1V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
EH1_k127_4398996_5	1123393.KB891316_gene1139	4.088e-26	110.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,1KTBG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
EH1_k127_4398996_4	243365.CV_1990	2.715e-26	111.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,2KU19@206351|Neisseriales	206351|Neisseriales	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
EH1_k127_4398996_0	1163617.SCD_n01886	1.398e-104	344.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
EH1_k127_4398996_2	292415.Tbd_1651	5.607e-74	273.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
EH1_k127_4398996_3	748280.NH8B_3711	3.764e-49	184.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,2KR2Z@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
EH1_k127_4398996_6	1123393.KB891317_gene2385	1.867e-16	83.0	COG3118@1|root,COG3118@2|Bacteria,1NWGI@1224|Proteobacteria,2W360@28216|Betaproteobacteria,1KRY1@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_20,Thioredoxin
EH1_k127_4400778_6	1000565.METUNv1_02026	1.444e-36	147.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
EH1_k127_4400778_5	159087.Daro_4085	4.559e-42	169.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,2KWYV@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH1_k127_4400778_1	1163617.SCD_n02840	2.44e-168	539.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
EH1_k127_4400778_4	1163617.SCD_n02841	2.391e-71	248.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
EH1_k127_4400778_3	1123393.KB891331_gene2914	1.801e-89	298.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,1KS28@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_4400778_2	1163617.SCD_n02843	1.962e-105	353.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2VMQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Inositol-1-monophosphatase	suhB2	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
EH1_k127_4400778_0	292415.Tbd_0159	4.12e-208	650.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KRI8@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
EH1_k127_4405601_0	1123392.AQWL01000003_gene184	1.897e-128	417.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KRF3@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
EH1_k127_4405601_1	381666.H16_A2069	7.44e-105	344.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,1K18P@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
EH1_k127_4409767_0	1266908.AQPB01000056_gene2062	2.159e-55	207.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WZVV@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,EAL,GGDEF,PAS,PAS_4
EH1_k127_4409767_1	713586.KB900536_gene1636	1.114e-33	142.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4409767_2	1123487.KB892834_gene2771	6.323e-31	138.0	COG0492@1|root,COG0492@2|Bacteria,1RKSQ@1224|Proteobacteria,2WBPB@28216|Betaproteobacteria,2KYR0@206389|Rhodocyclales	206389|Rhodocyclales	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
EH1_k127_4414678_1	1000565.METUNv1_02902	7.665e-39	148.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,2KWVU@206389|Rhodocyclales	206389|Rhodocyclales	F	Guanyl-specific ribonuclease Sa	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
EH1_k127_4414678_0	1000565.METUNv1_00784	4.17e-213	669.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,2KUMA@206389|Rhodocyclales	206389|Rhodocyclales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
EH1_k127_442335_1	335543.Sfum_2417	1.806e-42	161.0	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2MS52@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
EH1_k127_442335_0	335543.Sfum_0513	1.326e-257	811.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,42N3H@68525|delta/epsilon subdivisions,2WJSC@28221|Deltaproteobacteria,2MRMH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
EH1_k127_442335_2	335543.Sfum_0512	5.466e-06	51.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,42URY@68525|delta/epsilon subdivisions,2WQYF@28221|Deltaproteobacteria,2MRYS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_445475_0	748280.NH8B_1270	2.021e-148	472.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KPRX@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
EH1_k127_445475_1	522306.CAP2UW1_1706	8.719e-82	283.0	COG1639@1|root,COG1639@2|Bacteria,1PE3Q@1224|Proteobacteria,2WEH5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH1_k127_445475_2	497321.C664_10622	2.676e-08	57.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VRK0@28216|Betaproteobacteria,2KWDG@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH1_k127_4466628_3	1324957.K933_11981	2.775e-13	78.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23TI5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
EH1_k127_4466628_2	195250.CM001776_gene3491	4.771e-41	160.0	COG2391@1|root,COG2391@2|Bacteria,1G7H1@1117|Cyanobacteria,1H2AB@1129|Synechococcus	1117|Cyanobacteria	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_4466628_1	98439.AJLL01000085_gene4555	1.019e-41	160.0	COG2391@1|root,COG2391@2|Bacteria,1G6M9@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_4466628_0	1123228.AUIH01000008_gene2407	4.662e-113	372.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XH5C@135619|Oceanospirillales	135619|Oceanospirillales	P	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_4477246_0	1123392.AQWL01000003_gene260	8.592e-228	723.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
EH1_k127_4477246_1	1123392.AQWL01000003_gene252	3.259e-37	153.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2VMYV@28216|Betaproteobacteria,1KRYD@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4483018_2	1158165.KB898872_gene1132	2.186e-29	125.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1WXM3@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
EH1_k127_4483018_1	1158762.KB898039_gene1707	4.376e-58	203.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1WYTZ@135613|Chromatiales	135613|Chromatiales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH1_k127_4483018_0	1158165.KB898872_gene1134	8.872e-171	554.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T44K@1236|Gammaproteobacteria,1WXW4@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
EH1_k127_4505926_1	640081.Dsui_3403	1.655e-88	312.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,2KUGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971,DUF748
EH1_k127_4505926_0	1123392.AQWL01000011_gene2234	3.899e-90	302.0	COG4360@1|root,COG4360@2|Bacteria,1RB5I@1224|Proteobacteria,2W0KI@28216|Betaproteobacteria,1KS44@119069|Hydrogenophilales	119069|Hydrogenophilales	F	ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_450687_2	1123487.KB892836_gene3183	2.599e-17	83.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,2KVQ3@206389|Rhodocyclales	206389|Rhodocyclales	J	COG0480 Translation elongation factors (GTPases)	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
EH1_k127_450687_1	697282.Mettu_3163	5.57e-44	169.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1NMCM@1224|Proteobacteria,1SPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
EH1_k127_450687_0	1158182.KB905028_gene2511	5.857e-137	445.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Hpt,Response_reg
EH1_k127_4511254_1	1123393.KB891326_gene237	7.236e-56	200.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria,1KSW2@119069|Hydrogenophilales	119069|Hydrogenophilales	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
EH1_k127_4511254_0	1163617.SCD_n02051	2.297e-101	348.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VRWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH1_k127_4511254_2	1123393.KB891329_gene948	3.042e-34	136.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF1631,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_4
EH1_k127_452270_1	595460.RRSWK_05993	2.743e-40	151.0	COG0652@1|root,COG0652@2|Bacteria,2IZQS@203682|Planctomycetes	203682|Planctomycetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH1_k127_452270_0	272134.KB731324_gene3814	2.057e-111	372.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
EH1_k127_4559628_1	1163617.SCD_n01787	3.05e-72	250.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
EH1_k127_4559628_2	1500894.JQNN01000001_gene2317	1.663e-57	203.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,4746U@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
EH1_k127_4559628_4	887898.HMPREF0551_0432	3.042e-32	127.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,1K8EX@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
EH1_k127_4559628_5	1265502.KB905930_gene1556	1.322e-09	63.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria,4AEVS@80864|Comamonadaceae	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
EH1_k127_4559628_3	292415.Tbd_2105	7.696e-57	201.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,1KRM1@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
EH1_k127_4559628_0	1123392.AQWL01000001_gene1373	1.126e-83	278.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,1KRE3@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Orn/Lys/Arg decarboxylase, N-terminal domain	-	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
EH1_k127_4564587_0	1236959.BAMT01000002_gene1934	9.755e-134	428.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,2KKT7@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
EH1_k127_4564587_1	292415.Tbd_2504	1.328e-98	327.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,1KSYB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Shikimate dehydrogenase substrate binding domain	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
EH1_k127_4564646_0	1123393.KB891317_gene2264	6.169e-171	542.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria,1KSUB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
EH1_k127_4564646_4	472759.Nhal_3472	2.063e-53	199.0	2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,1SBQY@1236|Gammaproteobacteria,1WZRS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4564646_2	640081.Dsui_1261	3.264e-87	296.0	COG0784@1|root,COG0784@2|Bacteria,1QWFW@1224|Proteobacteria,2VPCN@28216|Betaproteobacteria,2KVZ3@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH1_k127_4564646_3	292415.Tbd_0747	2.089e-83	280.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1KSGX@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
EH1_k127_4564646_1	1123392.AQWL01000001_gene1357	4.206e-89	296.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase, U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
EH1_k127_45745_0	547559.Nmag_3602	6.475e-30	128.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,23U5C@183963|Halobacteria	183963|Halobacteria	S	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	SPP
EH1_k127_45745_1	1459636.NTE_00644	4.132e-08	61.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_457591_0	1288494.EBAPG3_24420	3.315e-317	981.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,3720I@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH1_k127_457591_1	640081.Dsui_1895	1.263e-74	254.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,2KYIA@206389|Rhodocyclales	206389|Rhodocyclales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
EH1_k127_457591_2	497321.C664_14604	3.617e-27	116.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria,2KXTS@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_458521_2	1123393.KB891332_gene2809	2.298e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,1R434@1224|Proteobacteria,2WEVM@28216|Betaproteobacteria,1KSZZ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH1_k127_458521_1	1304883.KI912532_gene3042	3.404e-72	250.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,2KW25@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH1_k127_458521_0	1163617.SCD_n01213	3.759e-81	276.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
EH1_k127_458521_3	292415.Tbd_0600	1.062e-23	103.0	2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,2VYWR@28216|Betaproteobacteria,1KT93@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_458521_4	1123393.KB891328_gene640	3.745e-22	98.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria,2W5JW@28216|Betaproteobacteria,1KT9H@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4589454_6	1163617.SCD_n02021	3.589e-91	308.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH1_k127_4589454_5	1121033.AUCF01000019_gene3705	2.32e-98	331.0	COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales	204441|Rhodospirillales	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
EH1_k127_4589454_9	292415.Tbd_2183	2.23e-36	144.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria,1KRVF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
EH1_k127_4589454_3	1123393.KB891316_gene1496	1.964e-126	412.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria,1KRJJ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
EH1_k127_4589454_1	748247.AZKH_0483	4.974e-167	529.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
EH1_k127_4589454_2	1123392.AQWL01000005_gene2925	8.133e-134	439.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,2VI70@28216|Betaproteobacteria,1KT0A@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Radical_SAM C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
EH1_k127_4589454_10	1123255.JHYS01000007_gene1605	2.587e-29	119.0	COG4309@1|root,COG4309@2|Bacteria,1N4MS@1224|Proteobacteria,2VU7H@28216|Betaproteobacteria,4AEZS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
EH1_k127_4589454_7	870187.Thini_2588	5.804e-56	198.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH1_k127_4589454_4	292415.Tbd_1406	2.914e-99	333.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2VK31@28216|Betaproteobacteria,1KRB6@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrate reductase gamma subunit	-	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
EH1_k127_4589454_8	292415.Tbd_1405	1.25e-49	192.0	COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,2VQI7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
EH1_k127_4589454_0	292415.Tbd_1404	5.477e-248	769.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,1KRHK@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Respiratory nitrate reductase beta C-terminal	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
EH1_k127_4627898_0	1122951.ATUE01000006_gene1113	3.405e-139	449.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,3NNA6@468|Moraxellaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH1_k127_4627898_5	1120999.JONM01000007_gene1808	1.864e-30	125.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,2KRD8@206351|Neisseriales	206351|Neisseriales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
EH1_k127_4627898_4	1123392.AQWL01000002_gene1848	1.276e-46	176.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,1KRSA@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
EH1_k127_4627898_3	1123367.C666_14735	2.544e-58	208.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,2KWEB@206389|Rhodocyclales	206389|Rhodocyclales	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
EH1_k127_4627898_1	768671.ThimaDRAFT_0979	4.824e-68	238.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_4627898_2	1123392.AQWL01000011_gene2233	5.082e-59	213.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH1_k127_4684237_9	1217718.ALOU01000037_gene2089	1.275e-12	67.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,1K2HB@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
EH1_k127_4684237_6	265072.Mfla_0594	4.6e-52	187.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,2KMU9@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
EH1_k127_4684237_1	1485544.JQKP01000019_gene30	2.268e-104	354.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,44V75@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
EH1_k127_4684237_2	1123393.KB891316_gene1358	2.419e-97	337.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,1KS9G@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
EH1_k127_4684237_4	580332.Slit_0949	6.508e-76	263.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,44W91@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
EH1_k127_4684237_5	1123392.AQWL01000001_gene1419	2.668e-53	192.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,1KSSJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	-	-	-	-	-	-	-	-	-	-	HPPK
EH1_k127_4684237_0	1123393.KB891316_gene1355	1.816e-174	559.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,1KSBC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
EH1_k127_4684237_3	522306.CAP2UW1_0390	2.024e-81	276.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,1KQS6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH1_k127_4684237_7	292415.Tbd_1509	1.163e-44	166.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,1KT4N@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
EH1_k127_4684237_8	1121035.AUCH01000015_gene2611	1.403e-21	96.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KU8U@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
EH1_k127_4685005_1	1123393.KB891316_gene1119	7.592e-38	148.0	COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria,1KSAM@119069|Hydrogenophilales	119069|Hydrogenophilales	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4685005_0	497321.C664_02615	7.503e-180	589.0	COG0308@1|root,COG0308@2|Bacteria,1PVVK@1224|Proteobacteria,2VIU3@28216|Betaproteobacteria,2KY1X@206389|Rhodocyclales	206389|Rhodocyclales	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
EH1_k127_4691258_0	292415.Tbd_1285	1.976e-143	460.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,1KRYE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	TOBE domain	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
EH1_k127_4691258_1	1123368.AUIS01000010_gene2378	1.332e-105	351.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	yeeY	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH1_k127_4691258_5	595494.Tola_0555	1.715e-24	109.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S46K@1236|Gammaproteobacteria,1Y4XZ@135624|Aeromonadales	135624|Aeromonadales	C	Cytochrome b/b6/petB	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
EH1_k127_4691258_4	85643.Tmz1t_1861	1.906e-40	151.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,2KWAK@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome B561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
EH1_k127_4691258_3	1000565.METUNv1_03325	4.889e-72	249.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,2KW1F@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
EH1_k127_4691258_2	118166.JH976537_gene4868	1.008e-93	314.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
EH1_k127_4691258_6	1000565.METUNv1_02160	1.824e-16	90.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria,2M011@206389|Rhodocyclales	206389|Rhodocyclales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
EH1_k127_4699661_2	1485544.JQKP01000001_gene1311	9.07e-83	280.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,44V5V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
EH1_k127_4699661_8	1123393.KB891333_gene2520	2.797e-41	163.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria,1KT1X@119069|Hydrogenophilales	119069|Hydrogenophilales	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
EH1_k127_4699661_4	519989.ECTPHS_01294	1.46e-62	238.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,1X13E@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH1_k127_4699661_5	1131553.JIBI01000006_gene1101	5.438e-62	224.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,371QS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Cytochrome c assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
EH1_k127_4699661_0	279714.FuraDRAFT_0450	9.866e-205	645.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,2KPW4@206351|Neisseriales	206351|Neisseriales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
EH1_k127_4699661_9	93220.LV28_22975	8.36e-33	130.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,1K8BW@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
EH1_k127_4699661_7	1163617.SCD_n02460	1.839e-49	183.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
EH1_k127_4699661_1	582744.Msip34_2392	7.146e-96	320.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KKEG@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
EH1_k127_4699661_6	497321.C664_13529	1.91e-58	209.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,2KWCD@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
EH1_k127_4699661_3	1123401.JHYQ01000014_gene862	3.886e-68	239.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
EH1_k127_4709619_2	1163617.SCD_n00909	2.433e-21	93.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
EH1_k127_4709619_0	640081.Dsui_3072	3.843e-160	522.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KUDS@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
EH1_k127_4709619_1	748247.AZKH_3085	2.143e-65	226.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KWB1@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
EH1_k127_4722617_0	395494.Galf_2887	0.0	1055.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
EH1_k127_4722617_1	1163617.SCD_n01637	1.906e-140	449.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methionine aminopeptidase	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
EH1_k127_4722617_2	1112274.KI911560_gene2101	2.614e-78	271.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,2KM41@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	GlnD_UR_UTase,HD,NTP_transf_2
EH1_k127_4759025_2	1144342.PMI40_01807	6.742e-48	174.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,472EQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH1_k127_4759025_1	1523503.JPMY01000009_gene630	6.485e-51	190.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,1S8A4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4759025_0	1163617.SCD_n01616	1.008e-86	307.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH1_k127_4780504_3	1122236.KB905141_gene1334	6.258e-22	108.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2VSKQ@28216|Betaproteobacteria,2KP39@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH1_k127_4780504_1	314264.ROS217_20172	1.392e-44	175.0	COG0500@1|root,COG0500@2|Bacteria,1N2EQ@1224|Proteobacteria,2UC80@28211|Alphaproteobacteria,46PKT@74030|Roseovarius	28211|Alphaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4780504_0	316067.Geob_0643	3.278e-74	258.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
EH1_k127_4780504_2	338966.Ppro_3335	9.869e-27	113.0	COG5442@1|root,COG5442@2|Bacteria,1REZ8@1224|Proteobacteria,42W1U@68525|delta/epsilon subdivisions,2WRE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar protein FlaF	-	-	-	ko:K06602	-	-	-	-	ko00000,ko02035	-	-	-	FlaF
EH1_k127_4784246_0	1123393.KB891330_gene902	0.0	1024.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KRGX@119069|Hydrogenophilales	119069|Hydrogenophilales	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
EH1_k127_481233_1	1123393.KB891329_gene1036	3.853e-97	323.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria,1KSY7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH1_k127_481233_0	1000565.METUNv1_02454	1.048e-130	433.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
EH1_k127_4824673_1	1163617.SCD_n01026	9.743e-162	511.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH1_k127_4824673_0	1173024.KI912151_gene1625	0.0	1043.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
EH1_k127_4829063_0	1123392.AQWL01000005_gene3134	5.726e-198	623.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,1KS9H@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Metalloenzyme superfamily	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
EH1_k127_4829063_2	292415.Tbd_2395	1.323e-53	190.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,1KT6W@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
EH1_k127_4829063_1	1123368.AUIS01000003_gene1736	5.016e-74	261.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1RYS4@1236|Gammaproteobacteria,2NC0F@225057|Acidithiobacillales	225057|Acidithiobacillales	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_4851115_1	1163617.SCD_n01923	8.599e-113	376.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
EH1_k127_4851115_2	1163617.SCD_n01922	8.363e-42	159.0	COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH1_k127_4851115_4	640081.Dsui_2885	4.233e-14	79.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
EH1_k127_4851115_0	395494.Galf_2288	4.001e-132	430.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,HD_5,Response_reg
EH1_k127_4851115_3	1123393.KB891316_gene1117	1.788e-37	143.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1KRAS@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Trypsin	-	-	-	ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
EH1_k127_4863240_0	1485544.JQKP01000001_gene1192	1.065e-87	309.0	2DQFH@1|root,336IU@2|Bacteria,1NE0H@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K20328	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
EH1_k127_4863240_1	316058.RPB_4106	9.625e-61	222.0	COG2357@1|root,COG2357@2|Bacteria,1QYWE@1224|Proteobacteria	1224|Proteobacteria	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4863240_2	1485544.JQKP01000003_gene272	7.922e-15	87.0	28V1B@1|root,2ZH4V@2|Bacteria,1PBEX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4904791_1	1123392.AQWL01000002_gene1898	7.115e-69	237.0	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,2WBPG@28216|Betaproteobacteria,1KSB5@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_4904791_0	292415.Tbd_2509	5.174e-191	609.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,1KRZS@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
EH1_k127_4904791_2	935567.JAES01000001_gene2151	3.117e-11	63.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X6V9@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	VM57_07835	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
EH1_k127_4933550_1	1000565.METUNv1_02785	1.294e-88	298.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,2KXF8@206389|Rhodocyclales	206389|Rhodocyclales	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
EH1_k127_4933550_0	323848.Nmul_A1953	8.607e-121	398.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,371V5@32003|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
EH1_k127_4936058_1	384765.SIAM614_11398	1.651e-65	228.0	28HU2@1|root,2Z80V@2|Bacteria,1QZ7A@1224|Proteobacteria	1224|Proteobacteria	C	Histidine carboxylase PI chain	-	-	4.1.1.22	ko:K01590	ko00340,ko01100,ko01110,map00340,map01100,map01110	-	R01167	RC00299	ko00000,ko00001,ko01000	-	-	-	HDC
EH1_k127_4936058_2	518766.Rmar_1239	8.391e-39	160.0	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes,1FJA7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
EH1_k127_4936058_0	1089550.ATTH01000001_gene804	7.74e-189	601.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1FK09@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
EH1_k127_4945341_2	1236959.BAMT01000002_gene1844	6.442e-68	237.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,2KM2T@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
EH1_k127_4945341_0	335283.Neut_1588	8.949e-135	449.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,37261@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
EH1_k127_4945341_1	748247.AZKH_0137	6.475e-75	263.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KUPW@206389|Rhodocyclales	206389|Rhodocyclales	DM	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
EH1_k127_4946060_2	1000565.METUNv1_02639	1.929e-05	51.0	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,2VWP5@28216|Betaproteobacteria,2KXGB@206389|Rhodocyclales	206389|Rhodocyclales	N	negative regulator of flagellin synthesis	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
EH1_k127_4946060_1	265072.Mfla_1953	1.454e-28	123.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,2VR6V@28216|Betaproteobacteria,2KMBU@206350|Nitrosomonadales	206350|Nitrosomonadales	N	flagella basal body P-ring formation protein FlgA	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
EH1_k127_4946060_0	1454004.AW11_00048	7.59e-43	170.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH1_k127_4946220_1	582744.Msip34_1392	1.139e-117	380.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria,2KME4@206350|Nitrosomonadales	206350|Nitrosomonadales	I	PFAM Carbamoyl-phosphate synthase L chain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH1_k127_4946220_0	1236959.BAMT01000001_gene1630	1.468e-306	948.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales	206350|Nitrosomonadales	CI	TIGRFAM oxaloacetate decarboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
EH1_k127_4946220_2	1123392.AQWL01000007_gene908	7.225e-39	147.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KSDR@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH1_k127_4982342_6	1485544.JQKP01000002_gene1365	8.208e-59	205.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
EH1_k127_4982342_4	580332.Slit_2472	2.524e-69	247.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
EH1_k127_4982342_3	62928.azo2760	1.767e-78	265.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,2KW9N@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
EH1_k127_4982342_5	1123393.KB891318_gene2183	8.714e-65	223.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1KRMF@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
EH1_k127_4982342_1	1123392.AQWL01000022_gene2179	1.77e-184	580.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KRDK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH1_k127_4982342_7	522306.CAP2UW1_3027	4.311e-58	203.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KQ1R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
EH1_k127_4982342_9	1123393.KB891316_gene1691	1.75e-20	94.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KRWJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DNA gyrase inhibitor YacG	-	-	-	-	-	-	-	-	-	-	-	-	YacG
EH1_k127_4982342_8	1049564.TevJSym_aw00360	8.584e-22	102.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH1_k127_4982342_2	1163617.SCD_n00391	3.117e-105	347.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
EH1_k127_4982342_0	1123393.KB891316_gene1689	2.089e-245	766.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,1KRC2@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
EH1_k127_4983352_0	1000565.METUNv1_00838	7.982e-269	848.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,2KV2V@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
EH1_k127_4983352_1	1163617.SCD_n01716	3.439e-145	466.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
EH1_k127_5014094_3	395495.Lcho_1775	6.014e-12	66.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria,1KK0E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Helix-turn-helix type 11	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
EH1_k127_5014094_0	748247.AZKH_1735	2.104e-99	345.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,2KUC4@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
EH1_k127_5014094_1	748247.AZKH_p0155	2.358e-88	302.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
EH1_k127_5014094_4	1198452.Jab_2c26160	4.998e-11	64.0	COG3614@1|root,COG4191@1|root,COG3614@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,475JP@75682|Oxalobacteraceae	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
EH1_k127_5014094_5	1150469.RSPPHO_00885	9.767e-11	73.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQTN@28211|Alphaproteobacteria,2JPPH@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
EH1_k127_5014094_2	1150469.RSPPHO_02505	1.402e-36	146.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2UK6R@28211|Alphaproteobacteria,2JUP0@204441|Rhodospirillales	204441|Rhodospirillales	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH1_k127_5022028_2	1163617.SCD_n01263	2.46e-222	698.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
EH1_k127_5022028_3	1163617.SCD_n01262	7.677e-118	390.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
EH1_k127_5022028_0	305700.B447_19809	1.092e-281	870.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
EH1_k127_5022028_1	1304883.KI912532_gene603	1.363e-223	698.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,2KV7G@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
EH1_k127_5022028_4	1163617.SCD_n00308	3.112e-100	335.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
EH1_k127_5022028_6	522306.CAP2UW1_4174	4.2e-32	132.0	COG0454@1|root,COG0456@2|Bacteria,1RJDS@1224|Proteobacteria,2VSVF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
EH1_k127_5022028_5	292415.Tbd_2525	8.273e-54	192.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
EH1_k127_5036861_2	1123392.AQWL01000004_gene2653	1.087e-102	343.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KRIX@119069|Hydrogenophilales	119069|Hydrogenophilales	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
EH1_k127_5036861_1	1123392.AQWL01000004_gene2654	3.034e-202	639.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KS0U@119069|Hydrogenophilales	119069|Hydrogenophilales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
EH1_k127_5036861_5	314285.KT71_17016	1.135e-18	92.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1J73G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
EH1_k127_5036861_6	62928.azo1347	8.775e-05	46.0	2DTX1@1|root,33N25@2|Bacteria,1NNNE@1224|Proteobacteria,2VYM2@28216|Betaproteobacteria,2KXGV@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3149
EH1_k127_5036861_0	1163617.SCD_n01230	1.738e-205	655.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
EH1_k127_5036861_4	1121035.AUCH01000020_gene2653	5.457e-44	169.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,2KWS2@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
EH1_k127_5036861_3	1120999.JONM01000005_gene3920	9.36e-79	266.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2VI19@28216|Betaproteobacteria,2KQ3I@206351|Neisseriales	206351|Neisseriales	N	flagellar motor switch protein	fliG1	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
EH1_k127_5049058_0	1123393.KB891316_gene1843	1.578e-200	629.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KRZW@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
EH1_k127_5049058_3	1123393.KB891316_gene1842	1.877e-34	140.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria,1KRYR@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5049058_1	1163617.SCD_n02708	1.222e-110	362.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
EH1_k127_5049058_2	1163617.SCD_n02707	2.342e-103	342.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
EH1_k127_5049622_2	1123393.KB891329_gene1034	2.036e-68	241.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,1KSYH@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
EH1_k127_5049622_8	1123393.KB891329_gene1033	8.96e-19	96.0	COG1129@1|root,COG1129@2|Bacteria,1PAYN@1224|Proteobacteria,2WC7Z@28216|Betaproteobacteria,1KT7W@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5049622_0	1123392.AQWL01000011_gene2242	1.845e-85	294.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,1KS5S@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Mammalian cell entry related domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5049622_5	614083.AWQR01000040_gene756	1.376e-51	201.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,4AE2G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5049622_4	1476583.DEIPH_ctg026orf0070	2.027e-57	205.0	COG2391@1|root,COG2391@2|Bacteria,1WK5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_5049622_6	693977.Deipr_0100	1.674e-45	168.0	COG2391@1|root,COG2391@2|Bacteria,1WKEK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_5049622_3	292415.Tbd_0976	6.184e-68	235.0	COG3255@1|root,COG3255@2|Bacteria,1N5G0@1224|Proteobacteria,2W311@28216|Betaproteobacteria	28216|Betaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
EH1_k127_5049622_7	1219031.BBJR01000068_gene1221	1.597e-26	113.0	COG4390@1|root,COG4390@2|Bacteria,1N8RK@1224|Proteobacteria,2VUJW@28216|Betaproteobacteria,4AI60@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2322)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2322
EH1_k127_5049622_1	582744.Msip34_0438	2.096e-84	284.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KMJS@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
EH1_k127_5059416_2	1123392.AQWL01000003_gene324	2.122e-63	224.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KRK3@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
EH1_k127_5059416_1	1175306.GWL_15080	7.362e-68	233.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,4743H@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Redoxin	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH1_k127_5059416_0	1123392.AQWL01000008_gene1216	3.482e-229	718.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,1KRG1@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Large family of predicted nucleotide-binding domains	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
EH1_k127_5072089_0	243231.GSU2350	1.231e-187	602.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
EH1_k127_5072089_1	1499967.BAYZ01000080_gene917	1.452e-27	119.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
EH1_k127_5077677_2	1163617.SCD_n00983	2.242e-07	56.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
EH1_k127_5077677_1	1163617.SCD_n00492	4.812e-139	451.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
EH1_k127_5077677_0	640081.Dsui_2420	9.472e-143	479.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
EH1_k127_5086248_1	1123253.AUBD01000001_gene1817	1.606e-26	113.0	COG1006@1|root,COG1006@2|Bacteria,1RHXT@1224|Proteobacteria,1S6C0@1236|Gammaproteobacteria,1XCS3@135614|Xanthomonadales	135614|Xanthomonadales	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q2
EH1_k127_5086248_0	338963.Pcar_2619	7.677e-155	503.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,43SD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
EH1_k127_5086248_2	1123253.AUBD01000001_gene1819	1.239e-17	88.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	mrpE	-	-	ko:K05562,ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
EH1_k127_5086248_4	1458427.BAWN01000006_gene469	1.216e-12	76.0	COG2212@1|root,COG2212@2|Bacteria	2|Bacteria	P	antiporter activity	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
EH1_k127_5086248_3	1123253.AUBD01000001_gene1821	5.347e-14	77.0	COG1320@1|root,COG1320@2|Bacteria,1RH17@1224|Proteobacteria,1S6Q4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na H antiporter	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
EH1_k127_5092310_0	292415.Tbd_0342	1.259e-173	553.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KSAC@119069|Hydrogenophilales	119069|Hydrogenophilales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
EH1_k127_5092310_2	1163617.SCD_n02644	3.99e-44	170.0	COG5456@1|root,COG5456@2|Bacteria,1N6AR@1224|Proteobacteria,2VU84@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
EH1_k127_5092310_1	292415.Tbd_0699	1.491e-52	189.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,1KRSB@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RimP C-terminal SH3 domain	-	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
EH1_k127_5132232_0	1485544.JQKP01000002_gene1502	3.937e-181	576.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,44VBN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
EH1_k127_5132232_3	1538295.JY96_09055	1.202e-22	108.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,1KKT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Rod shape-determining protein mreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
EH1_k127_5132232_2	1144319.PMI16_03164	6.154e-64	230.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,47326@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
EH1_k127_5132232_1	1163617.SCD_n00097	7.404e-112	362.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
EH1_k127_5150392_0	1123392.AQWL01000004_gene2701	6.08e-121	391.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,1KREF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
EH1_k127_5150392_2	292415.Tbd_0595	1.724e-38	156.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KRFP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
EH1_k127_5150392_1	426114.THI_2197	2.43e-100	330.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KJ7J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
EH1_k127_5151910_0	1123392.AQWL01000002_gene1712	6.231e-160	513.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KSYA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH1_k127_5151910_1	292415.Tbd_0022	4.223e-69	236.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KSYA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH1_k127_5173853_0	1123393.KB891317_gene2469	1.435e-258	805.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria,1KSGV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,FlpD,Pyr_redox_2
EH1_k127_5173853_1	292415.Tbd_1648	1.867e-50	181.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
EH1_k127_5198176_2	795666.MW7_0759	3.984e-91	306.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
EH1_k127_5198176_1	795666.MW7_0758	1.538e-95	328.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,1K50V@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
EH1_k127_5198176_0	684949.ATTJ01000001_gene2130	7.78e-137	442.0	COG0397@1|root,COG0397@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
EH1_k127_5212426_1	395493.BegalDRAFT_3046	7.221e-64	222.0	COG2010@1|root,COG2010@2|Bacteria,1RD0F@1224|Proteobacteria,1SPHI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
EH1_k127_5212426_2	1163617.SCD_n00150	3.889e-59	211.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
EH1_k127_5212426_0	1000565.METUNv1_03022	5.891e-91	304.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2WEGN@28216|Betaproteobacteria,2KVA1@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
EH1_k127_5212943_1	75379.Tint_0683	1.527e-52	192.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,1KM3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	hydG	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
EH1_k127_5212943_0	1000565.METUNv1_02936	9.468e-87	291.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,2KUW6@206389|Rhodocyclales	206389|Rhodocyclales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
EH1_k127_5212943_2	1163617.SCD_n00318	2.051e-43	173.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
EH1_k127_5212943_3	1123368.AUIS01000021_gene983	2.562e-28	121.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,2ND8W@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
EH1_k127_5212943_4	713587.THITH_02080	2.802e-28	119.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1WY76@135613|Chromatiales	135613|Chromatiales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
EH1_k127_5226735_2	640510.BC1001_1310	2.578e-05	47.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,1K3UW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Chromate resistance	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH1_k127_5226735_0	1348657.M622_06240	1.519e-255	792.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,2KV7A@206389|Rhodocyclales	206389|Rhodocyclales	P	Chromate Ion Transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
EH1_k127_5226735_1	1163617.SCD_n02014	1.355e-32	133.0	COG0607@1|root,COG0607@2|Bacteria,1NBYS@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_5230677_1	1286631.X805_29000	1.812e-45	177.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,2VPEA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
EH1_k127_5230677_2	292415.Tbd_1198	7.216e-21	100.0	2BZ72@1|root,32Z0T@2|Bacteria,1NBTY@1224|Proteobacteria,2VX7F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5230677_0	768671.ThimaDRAFT_3709	3.233e-70	243.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1X0AG@135613|Chromatiales	135613|Chromatiales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
EH1_k127_5234670_1	765914.ThisiDRAFT_0321	2.217e-59	213.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WXHR@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
EH1_k127_5234670_0	1158762.KB898039_gene1706	2.165e-284	901.0	COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg
EH1_k127_5234670_2	1266908.AQPB01000053_gene603	1.763e-34	154.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXR1@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
EH1_k127_5235972_1	1122604.JONR01000014_gene293	1.334e-52	190.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1X2ZU@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH1_k127_5235972_0	1120999.JONM01000003_gene2643	3.048e-57	217.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,2KPC0@206351|Neisseriales	206351|Neisseriales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
EH1_k127_5235972_2	1266925.JHVX01000001_gene2509	2.475e-11	65.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,373MD@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
EH1_k127_5238795_7	380703.AHA_1489	1.621e-18	87.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1Y3GZ@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
EH1_k127_5238795_6	1123393.KB891330_gene780	9.272e-39	150.0	2DPBX@1|root,331FU@2|Bacteria,1NB0X@1224|Proteobacteria,2VX47@28216|Betaproteobacteria,1KSRG@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5238795_1	1288494.EBAPG3_21760	1.21e-68	240.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,3732H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
EH1_k127_5238795_2	1123392.AQWL01000018_gene77	3.135e-60	216.0	COG1051@1|root,COG1051@2|Bacteria,1QUAQ@1224|Proteobacteria,2WH4Y@28216|Betaproteobacteria	28216|Betaproteobacteria	F	NUDIX hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
EH1_k127_5238795_5	1429851.X548_12550	1.131e-43	166.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,1S60C@1236|Gammaproteobacteria,1X7HP@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH1_k127_5238795_3	395494.Galf_1985	6.938e-56	203.0	2CMG5@1|root,32SEP@2|Bacteria,1N1C2@1224|Proteobacteria,2W882@28216|Betaproteobacteria,44WI5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5238795_4	1121035.AUCH01000014_gene2406	4.357e-45	171.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2WEG6@28216|Betaproteobacteria,2KW5A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	cc43	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_5238795_0	1163617.SCD_n01249	4.894e-145	470.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
EH1_k127_527928_1	96561.Dole_2771	3.383e-46	177.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42S61@68525|delta/epsilon subdivisions,2X5SR@28221|Deltaproteobacteria,2MPFW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
EH1_k127_527928_0	693661.Arcve_0284	3.36e-67	244.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVR7@28890|Euryarchaeota,245V0@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH1_k127_5304477_0	1123368.AUIS01000005_gene485	2.44e-237	740.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,2NBSD@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
EH1_k127_5304477_1	1123368.AUIS01000005_gene484	1.339e-127	417.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,2NC9T@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
EH1_k127_5304477_2	1265502.KB905968_gene1258	2.82e-29	119.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,4AAZ5@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
EH1_k127_5305729_0	557598.LHK_02865	1.149e-144	462.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KPHF@206351|Neisseriales	206351|Neisseriales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
EH1_k127_5305729_2	1163617.SCD_n01253	7.868e-62	217.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Iron-sulfur cluster assembly transcription factor IscR	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
EH1_k127_5305729_1	1123392.AQWL01000003_gene376	5.892e-78	263.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,1KSH1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
EH1_k127_5311076_1	1123393.KB891316_gene1305	1.205e-194	616.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,1KSEZ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
EH1_k127_5311076_4	1123393.KB891316_gene1309	2.475e-34	138.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,2WBQA@28216|Betaproteobacteria,1KSCY@119069|Hydrogenophilales	119069|Hydrogenophilales	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
EH1_k127_5311076_0	396588.Tgr7_0871	7.917e-232	729.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1WXDW@135613|Chromatiales	135613|Chromatiales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
EH1_k127_5311076_3	292415.Tbd_2140	9.606e-86	304.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
EH1_k127_5311076_2	1123368.AUIS01000009_gene2506	1.969e-102	336.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,2NC9C@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
EH1_k127_5315555_2	1123393.KB891328_gene622	1.992e-15	79.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,1KRPM@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH1_k127_5315555_0	640081.Dsui_3536	5.856e-224	704.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KU6P@206389|Rhodocyclales	206389|Rhodocyclales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
EH1_k127_5315555_1	1163617.SCD_n01389	3.012e-85	285.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH1_k127_5318278_1	580332.Slit_2387	4.693e-57	202.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
EH1_k127_5318278_0	1163617.SCD_n01145	3.097e-82	282.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
EH1_k127_5318278_2	497321.C664_17487	4.425e-15	74.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria,2KXEJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH1_k127_5344572_2	1163617.SCD_n00064	5.922e-12	72.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH1_k127_5344572_1	765911.Thivi_1927	9.226e-24	117.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH1_k127_5344572_0	1123392.AQWL01000005_gene2880	2.331e-60	216.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	DUF1929,Laminin_G_3,Metallophos
EH1_k127_536520_2	1283284.AZUK01000001_gene440	0.000488	48.0	COG2199@1|root,COG3614@1|root,COG2199@2|Bacteria,COG3614@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_8,PAS_9
EH1_k127_536520_1	312153.Pnuc_1322	1.46e-29	119.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria,1KB20@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
EH1_k127_536520_0	1454004.AW11_01954	2.619e-139	448.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KPU3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH1_k127_53778_0	640081.Dsui_2546	4.908e-230	722.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,2KV6T@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA binding	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
EH1_k127_5390310_3	1489678.RDMS_02220	6.362e-12	68.0	COG0589@1|root,COG0589@2|Bacteria,1WJVG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
EH1_k127_5390310_0	717606.PaecuDRAFT_4792	2.657e-76	268.0	COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,26QEB@186822|Paenibacillaceae	91061|Bacilli	C	nitroreductase	frp	-	-	-	-	-	-	-	-	-	-	iYO844.BSU07830	Nitroreductase
EH1_k127_5390310_2	1046714.AMRX01000001_gene1824	4.319e-13	74.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_5390310_1	1000565.METUNv1_04023	2.883e-44	166.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VJK2@28216|Betaproteobacteria,2KUNA@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH1_k127_5406694_1	1163617.SCD_n01156	2.577e-210	661.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
EH1_k127_5406694_4	1163617.SCD_n01157	1.024e-69	241.0	COG3439@1|root,COG3439@2|Bacteria,1N4Z5@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH1_k127_5406694_2	557598.LHK_02039	5.23e-196	619.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,2KPX7@206351|Neisseriales	206351|Neisseriales	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
EH1_k127_5406694_0	748280.NH8B_3196	5.824e-220	687.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,2KPG5@206351|Neisseriales	206351|Neisseriales	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
EH1_k127_5406694_3	580332.Slit_2076	1.284e-91	309.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,44V84@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
EH1_k127_5422003_1	1101195.Meth11DRAFT_2050	1.072e-71	250.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,2KM02@206350|Nitrosomonadales	206350|Nitrosomonadales	HL	Thiamine monophosphate synthase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
EH1_k127_5422003_2	292415.Tbd_0026	2.559e-22	101.0	2BWYA@1|root,32WXT@2|Bacteria,1N26T@1224|Proteobacteria,2VXGX@28216|Betaproteobacteria,1KT5N@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5422003_0	1123393.KB891332_gene2752	8.763e-96	317.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,1KRQG@119069|Hydrogenophilales	119069|Hydrogenophilales	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
EH1_k127_542964_1	1123392.AQWL01000002_gene2049	5.24e-63	223.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,1KSX5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
EH1_k127_542964_0	292415.Tbd_0315	3.668e-108	353.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1KS1S@119069|Hydrogenophilales	119069|Hydrogenophilales	E	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH1_k127_5439821_2	331869.BAL199_07458	1.723e-41	162.0	COG2520@1|root,COG2520@2|Bacteria,1MZTC@1224|Proteobacteria,2UE8C@28211|Alphaproteobacteria,4BSBW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
EH1_k127_5439821_1	1316936.K678_12564	2.626e-60	221.0	COG0535@1|root,COG3914@1|root,COG0535@2|Bacteria,COG3914@2|Bacteria,1QU3U@1224|Proteobacteria,2TVYA@28211|Alphaproteobacteria,2JZ4F@204441|Rhodospirillales	204441|Rhodospirillales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
EH1_k127_5439821_0	1168059.KB899087_gene744	1.092e-67	242.0	COG0455@1|root,COG4122@1|root,COG0455@2|Bacteria,COG4122@2|Bacteria,1PFY1@1224|Proteobacteria,2VB4H@28211|Alphaproteobacteria,3F219@335928|Xanthobacteraceae	28211|Alphaproteobacteria	D	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
EH1_k127_5439821_3	338966.Ppro_1838	3.273e-13	74.0	2E8BS@1|root,332QF@2|Bacteria,1N9X2@1224|Proteobacteria,431DN@68525|delta/epsilon subdivisions,2WX5W@28221|Deltaproteobacteria,43VDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5455716_0	666681.M301_0034	2.743e-211	662.0	COG3185@1|root,COG3185@2|Bacteria,1R5AJ@1224|Proteobacteria,2W11Y@28216|Betaproteobacteria,2KKMU@206350|Nitrosomonadales	206350|Nitrosomonadales	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5455716_1	1344012.ATMI01000054_gene1636	2.763e-99	331.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria,4BTIK@82986|Tatumella	1236|Gammaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
EH1_k127_5455716_3	595537.Varpa_2411	3.545e-65	230.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,2VQEC@28216|Betaproteobacteria,4ADVM@80864|Comamonadaceae	28216|Betaproteobacteria	F	Peptidase C26	guaA_2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
EH1_k127_5455716_2	377629.TERTU_0825	1.47e-81	273.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,2PPJ4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	IV02_11925	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
EH1_k127_5464749_0	292415.Tbd_1189	1.055e-20	100.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1KS8C@119069|Hydrogenophilales	119069|Hydrogenophilales	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
EH1_k127_5468172_3	1123393.KB891328_gene604	1.011e-08	56.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,1KT6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
EH1_k127_5468172_1	292415.Tbd_0564	3.207e-123	402.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,1KSVE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
EH1_k127_5468172_0	1123392.AQWL01000004_gene2735	2.551e-312	973.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KSXW@119069|Hydrogenophilales	119069|Hydrogenophilales	F	5'-nucleotidase, C-terminal domain	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
EH1_k127_5468172_2	1121935.AQXX01000125_gene768	1.086e-23	115.0	COG0784@1|root,COG0784@2|Bacteria,1N1YE@1224|Proteobacteria,1S9PD@1236|Gammaproteobacteria,1XPXE@135619|Oceanospirillales	135619|Oceanospirillales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH1_k127_5480970_1	1123393.KB891316_gene1118	3.009e-96	326.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2W1SC@28216|Betaproteobacteria,1KSI9@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
EH1_k127_5480970_0	316067.Geob_1385	4.198e-130	428.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
EH1_k127_5480970_2	1123392.AQWL01000009_gene1106	1.686e-68	243.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,1KSS1@119069|Hydrogenophilales	119069|Hydrogenophilales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH1_k127_5490152_1	1163617.SCD_n01186	2.032e-104	350.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
EH1_k127_5490152_0	1163617.SCD_n01875	8.723e-135	436.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
EH1_k127_5507816_0	1123393.KB891331_gene2894	1.039e-224	700.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,1KSAV@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
EH1_k127_5507816_2	1121035.AUCH01000002_gene1549	3.612e-47	172.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
EH1_k127_5507816_1	1163617.SCD_n00064	2.817e-97	326.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH1_k127_5512000_0	1123392.AQWL01000008_gene1171	1.528e-111	376.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,1KSI8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
EH1_k127_5523215_3	85643.Tmz1t_3614	8.903e-62	222.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
EH1_k127_5523215_2	1123393.KB891330_gene752	1.84e-90	304.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,1KSXN@119069|Hydrogenophilales	119069|Hydrogenophilales	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
EH1_k127_5523215_1	1123392.AQWL01000002_gene2110	3.361e-139	449.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,1KRA8@119069|Hydrogenophilales	119069|Hydrogenophilales	U	SRP54-type protein, helical bundle domain	-	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
EH1_k127_5523215_0	1163617.SCD_n02637	4.248e-179	572.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH1_k127_5523215_4	583345.Mmol_1750	2.409e-54	197.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,2KM4Y@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH1_k127_5523215_5	582744.Msip34_1921	1.051e-27	115.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,2KM4Y@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH1_k127_5525933_2	216595.PFLU_4648	6.08e-10	61.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1YQX1@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
EH1_k127_5525933_0	1123392.AQWL01000008_gene1209	3.206e-87	293.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,1KSPN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
EH1_k127_5525933_1	1123261.AXDW01000009_gene101	2.471e-73	258.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XC3C@135614|Xanthomonadales	135614|Xanthomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
EH1_k127_5527027_0	1095769.CAHF01000009_gene1397	6.943e-164	520.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
EH1_k127_5527027_1	1123392.AQWL01000007_gene876	1.32e-123	398.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KSMU@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH1_k127_5527027_2	1123393.KB891333_gene2641	4.536e-11	63.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH1_k127_5562989_2	1163617.SCD_n00396	1.513e-48	186.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
EH1_k127_5562989_3	1123392.AQWL01000005_gene3093	1.195e-40	158.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,1KSWM@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
EH1_k127_5562989_0	1163617.SCD_n00405	2.488e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2WEGC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulatory protein ompR	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_5562989_1	1123392.AQWL01000005_gene3090	6.176e-77	273.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2WGUD@28216|Betaproteobacteria,1KSJ4@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
EH1_k127_5567496_2	1007105.PT7_2067	1.749e-17	83.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,3T20J@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
EH1_k127_5567496_0	640081.Dsui_3386	1.316e-55	206.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VSCC@28216|Betaproteobacteria,2KYUB@206389|Rhodocyclales	206389|Rhodocyclales	K	Flagellar regulatory protein FleQ	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH1_k127_5567496_1	1003200.AXXA_16697	2.089e-23	102.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJXQ@28216|Betaproteobacteria,3T2HD@506|Alcaligenaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3
EH1_k127_557477_2	1123367.C666_17020	7.807e-86	291.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KU9B@206389|Rhodocyclales	206389|Rhodocyclales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
EH1_k127_557477_1	292415.Tbd_1677	9.443e-108	352.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KRDV@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
EH1_k127_557477_0	1123392.AQWL01000008_gene1181	4.12e-172	544.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KRGT@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
EH1_k127_5574931_6	1485544.JQKP01000007_gene1971	5.542e-64	223.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,44VZS@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
EH1_k127_5574931_1	1123392.AQWL01000011_gene2252	3.61e-178	570.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria,1KRY8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
EH1_k127_5574931_7	557598.LHK_02520	2.469e-60	218.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,2VV8V@28216|Betaproteobacteria,2KRHP@206351|Neisseriales	206351|Neisseriales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
EH1_k127_5574931_3	1163617.SCD_n02560	4.225e-149	483.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
EH1_k127_5574931_0	1123392.AQWL01000005_gene3071	2.784e-190	620.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,1KRHD@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
EH1_k127_5574931_4	292415.Tbd_2336	2.291e-140	455.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1KRX6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
EH1_k127_5574931_5	497321.C664_14364	1.971e-82	290.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KV5Z@206389|Rhodocyclales	206389|Rhodocyclales	JM	Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
EH1_k127_5574931_9	640081.Dsui_1591	5.709e-12	66.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,2KUHQ@206389|Rhodocyclales	206389|Rhodocyclales	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
EH1_k127_5574931_2	1123393.KB891316_gene1657	5.403e-177	561.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,1KS63@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
EH1_k127_5574931_8	1266925.JHVX01000008_gene272	4.441e-36	142.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,3723Y@32003|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH1_k127_5623036_0	631362.Thi970DRAFT_03521	4.2e-159	508.0	COG0547@1|root,COG0547@2|Bacteria,1QDR6@1224|Proteobacteria,1T9UH@1236|Gammaproteobacteria,1WW56@135613|Chromatiales	135613|Chromatiales	E	PFAM Glycosyl transferase, family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH1_k127_5623036_3	1123393.KB891330_gene829	1.355e-34	143.0	COG2146@1|root,COG2146@2|Bacteria,1PT5F@1224|Proteobacteria,2WAE5@28216|Betaproteobacteria,1KT6Z@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
EH1_k127_5623036_2	1000565.METUNv1_03020	2.743e-83	291.0	COG1566@1|root,COG1566@2|Bacteria,1QW95@1224|Proteobacteria,2WI8S@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH1_k127_5623036_1	365044.Pnap_0081	4.483e-118	394.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2VHS2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH1_k127_5623246_0	1163617.SCD_n01926	0.0	1080.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
EH1_k127_5623246_1	1163617.SCD_n01925	1.27e-127	412.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH1_k127_5630241_6	497321.C664_17982	1.039e-25	110.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,2KVMW@206389|Rhodocyclales	206389|Rhodocyclales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
EH1_k127_5630241_3	640081.Dsui_0447	2.113e-57	209.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,2KWCR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
EH1_k127_5630241_5	292415.Tbd_0250	3.711e-31	138.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
EH1_k127_5630241_4	292415.Tbd_0249	7.049e-50	189.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VW39@28216|Betaproteobacteria,1KS2K@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH1_k127_5630241_1	1123392.AQWL01000002_gene2003	2.91e-86	292.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,1KRJG@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH1_k127_5630241_2	292415.Tbd_0247	5.748e-75	265.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,1KSQF@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
EH1_k127_5630241_0	1163617.SCD_n00216	3.413e-201	633.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_5658304_5	1288494.EBAPG3_9070	7.132e-39	147.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,3736X@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
EH1_k127_5658304_4	1123393.KB891316_gene1513	7.155e-48	181.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,1KS8A@119069|Hydrogenophilales	119069|Hydrogenophilales	D	TolA binding protein trimerisation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TolA_bind_tri
EH1_k127_5658304_2	85643.Tmz1t_0779	5.738e-94	313.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,2KUF1@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
EH1_k127_5658304_1	1042375.AFPL01000056_gene2383	3.933e-96	322.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
EH1_k127_5658304_0	580332.Slit_1695	5.801e-133	433.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH1_k127_5658304_6	1485544.JQKP01000003_gene120	5.99e-28	123.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH1_k127_5658304_3	1163617.SCD_n00818	1.737e-88	293.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH1_k127_5679087_6	491952.Mar181_0643	3.061e-37	141.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XKSN@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
EH1_k127_5679087_5	292415.Tbd_1027	4.882e-66	229.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KRQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
EH1_k127_5679087_2	522306.CAP2UW1_0972	4.001e-93	310.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_5679087_1	522306.CAP2UW1_0973	1.081e-103	360.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH1_k127_5679087_3	748247.AZKH_3437	3.082e-88	296.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,2KW1K@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_5679087_4	1071679.BG57_20650	5.226e-84	302.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1K16K@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH1_k127_5679087_0	1163617.SCD_n01386	2.548e-154	498.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
EH1_k127_5687157_0	279714.FuraDRAFT_3033	5.946e-244	767.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,2KPQ4@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
EH1_k127_5687157_2	395494.Galf_1540	3.611e-69	239.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,44VU9@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
EH1_k127_5687157_3	292415.Tbd_0092	2.069e-48	175.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1KRSD@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
EH1_k127_5687157_1	292415.Tbd_0091	2.511e-195	611.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,1KRGZ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH1_k127_5687430_2	1123368.AUIS01000023_gene901	2.311e-39	151.0	2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5687430_1	1123392.AQWL01000002_gene1990	2.464e-54	194.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria,1KT1E@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_5687430_0	322710.Avin_29240	2.724e-127	412.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
EH1_k127_5688972_2	292415.Tbd_0608	8.779e-46	168.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KS8B@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ribonuclease B OB domain	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
EH1_k127_5688972_0	204773.HEAR1278	3.862e-85	288.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,472IM@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
EH1_k127_5688972_1	292415.Tbd_0777	1.905e-64	237.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,1KRP4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
EH1_k127_5688972_3	1236959.BAMT01000001_gene1551	6.116e-28	115.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,2KKQJ@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
EH1_k127_569780_6	1033802.SSPSH_001317	1.458e-26	118.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,1SEQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CbiX	cbiX	-	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
EH1_k127_569780_4	522306.CAP2UW1_2961	1.053e-44	166.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2VW71@28216|Betaproteobacteria	28216|Betaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_569780_2	768671.ThimaDRAFT_2301	6.874e-54	192.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S9TF@1236|Gammaproteobacteria,1X140@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
EH1_k127_569780_5	1121035.AUCH01000002_gene1476	2.2e-30	130.0	2E80B@1|root,332EM@2|Bacteria,1N7PZ@1224|Proteobacteria,2VVZX@28216|Betaproteobacteria,2KXET@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_569780_7	1224163.B841_05390	1e-20	99.0	COG3431@1|root,COG3431@2|Bacteria,2H8J4@201174|Actinobacteria,22NUM@1653|Corynebacteriaceae	201174|Actinobacteria	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
EH1_k127_569780_9	198628.Dda3937_00496	3.655e-08	62.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,2JCCZ@204037|Dickeya	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	1.3.1.74,3.4.21.107	ko:K04771,ko:K04772,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
EH1_k127_569780_1	395494.Galf_1674	2.033e-54	196.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria	1224|Proteobacteria	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
EH1_k127_569780_0	62928.azo1277	5.344e-68	237.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,2KWCA@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
EH1_k127_569780_3	1485544.JQKP01000004_gene441	1.537e-48	177.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2WGWV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
EH1_k127_5723345_1	1123504.JQKD01000034_gene2745	1.46e-68	236.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,4AAIH@80864|Comamonadaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
EH1_k127_5723345_0	580332.Slit_0513	1.983e-89	305.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria,44VIP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH1_k127_5724181_0	861299.J421_5885	1.654e-145	486.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1ZUID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
EH1_k127_5725223_0	99598.Cal7507_3738	8.13e-164	537.0	COG3299@1|root,COG3299@2|Bacteria,1G6U3@1117|Cyanobacteria	1117|Cyanobacteria	T	protein, phage tail-like region	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,Sortilin-Vps10
EH1_k127_5725223_1	99598.Cal7507_3739	1.649e-28	117.0	COG3292@1|root,COG3292@2|Bacteria,1G8JD@1117|Cyanobacteria	1117|Cyanobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
EH1_k127_5725445_0	1121091.AUMP01000013_gene3303	8.308e-17	82.0	COG1028@1|root,COG1028@2|Bacteria,1U9MA@1239|Firmicutes,4IPMW@91061|Bacilli	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
EH1_k127_5725445_1	1165841.SULAR_04738	2.317e-06	55.0	2C0H6@1|root,32R70@2|Bacteria,1NQU5@1224|Proteobacteria	1224|Proteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
EH1_k127_5730319_1	580332.Slit_2116	1.586e-75	258.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
EH1_k127_5730319_0	1123393.KB891316_gene1190	1.003e-232	722.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1KRBS@119069|Hydrogenophilales	119069|Hydrogenophilales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH1_k127_5730319_2	1112274.KI911560_gene2498	1.575e-23	114.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,2KMAC@206350|Nitrosomonadales	206350|Nitrosomonadales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
EH1_k127_5742323_1	1500894.JQNN01000001_gene3127	8.565e-72	250.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4768Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HATPase_c,HisKA,Response_reg
EH1_k127_5742323_0	580332.Slit_1183	3.161e-81	280.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,44WNG@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH1_k127_5742323_2	765913.ThidrDRAFT_1237	2.401e-53	208.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	bvgS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009268,GO:0009628,GO:0009927,GO:0009987,GO:0010447,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg,SBP_bac_3
EH1_k127_5755263_1	640081.Dsui_3038	2.068e-87	290.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
EH1_k127_5755263_0	1163617.SCD_n00952	2.425e-184	588.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
EH1_k127_5755263_2	402777.KB235904_gene4108	1.799e-71	260.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
EH1_k127_5755263_3	292415.Tbd_2784	6.455e-53	193.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
EH1_k127_5755263_4	742159.HMPREF0004_0823	5.386e-08	58.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,3T3VA@506|Alcaligenaceae	28216|Betaproteobacteria	D	Sporulation related domain	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH1_k127_5759154_1	1123392.AQWL01000006_gene670	1.18e-166	548.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KS69@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH1_k127_5759154_2	1123392.AQWL01000006_gene671	4.456e-154	492.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1KSA3@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH1_k127_5759154_4	1123393.KB891316_gene1951	1.676e-51	188.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,1KSC9@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosyl transferase domain	-	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
EH1_k127_5759154_5	1123487.KB892834_gene2868	2.373e-39	159.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,2KWP7@206389|Rhodocyclales	206389|Rhodocyclales	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
EH1_k127_5759154_3	1123392.AQWL01000006_gene674	2.112e-72	271.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,1KRQ7@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
EH1_k127_5759154_0	1123392.AQWL01000006_gene675	1.532e-182	593.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,1KSA2@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA photolyase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_photolyase,FAD_binding_7
EH1_k127_5759952_3	1249627.D779_2398	4.062e-89	306.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1WXA2@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,Response_reg
EH1_k127_5759952_1	1123393.KB891327_gene291	1.169e-174	556.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,1KRGF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
EH1_k127_5759952_4	1123392.AQWL01000003_gene472	3.367e-52	198.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,1KSZF@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobD/Cbib protein	-	-	-	-	-	-	-	-	-	-	-	-	CobD_Cbib
EH1_k127_5759952_5	1123393.KB891327_gene289	9.234e-35	140.0	COG3449@1|root,COG3449@2|Bacteria,1N79X@1224|Proteobacteria,2VWWR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5759952_2	1163617.SCD_n00859	3.925e-112	372.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_5759952_0	323259.Mhun_1141	1.361e-245	770.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,2N916@224756|Methanomicrobia	224756|Methanomicrobia	G	PEP-utilising enzyme, TIM barrel domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH1_k127_577429_0	1163617.SCD_n02021	1.208e-141	460.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH1_k127_5790530_3	1123392.AQWL01000022_gene2186	1.024e-09	60.0	COG3914@1|root,COG3914@2|Bacteria,1QU3U@1224|Proteobacteria,2WH8E@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Glycos_transf_2,Methyltransf_23,TPR_16,TPR_8
EH1_k127_5790530_1	243233.MCA1512	2.212e-112	385.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria,1XGYR@135618|Methylococcales	1236|Gammaproteobacteria	M	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
EH1_k127_5790530_2	1123393.KB891329_gene910	8.336e-27	111.0	COG1555@1|root,COG1555@2|Bacteria,1PWT6@1224|Proteobacteria,2WCC0@28216|Betaproteobacteria,1KTEC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
EH1_k127_5790530_0	62928.azo3292	9.016e-119	387.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
EH1_k127_5795766_1	396588.Tgr7_3302	8.923e-129	415.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
EH1_k127_5795766_0	62928.azo3637	1.904e-179	570.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,2KVQ1@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
EH1_k127_5813776_1	1366050.N234_14350	6.094e-47	173.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,2WFVC@28216|Betaproteobacteria,1KI6J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
EH1_k127_5813776_0	261292.Nit79A3_3087	5.612e-51	194.0	COG5544@1|root,COG5544@2|Bacteria,1QU58@1224|Proteobacteria,2VQZ5@28216|Betaproteobacteria,3720M@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5815043_0	1123393.KB891316_gene2121	3.879e-156	500.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1KT46@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH1_k127_5815043_1	1123393.KB891316_gene2122	8.676e-75	254.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KT21@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH1_k127_5821200_6	159087.Daro_1526	1.074e-28	117.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,2KY4U@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
EH1_k127_5821200_0	85643.Tmz1t_4070	2.503e-225	708.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2WGIZ@28216|Betaproteobacteria,2KZPP@206389|Rhodocyclales	206389|Rhodocyclales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
EH1_k127_5821200_1	314345.SPV1_12415	1.731e-151	492.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria	1224|Proteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH1_k127_5821200_5	1123400.KB904755_gene2631	2.852e-46	178.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH1_k127_5821200_2	1163617.SCD_n00481	1.731e-147	482.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
EH1_k127_5821200_3	543728.Vapar_6289	8.743e-97	332.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2WHKM@28216|Betaproteobacteria,4AJZE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH1_k127_5821200_4	1123487.KB892857_gene2442	8.78e-76	259.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,2KUBI@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_5823897_1	395495.Lcho_0488	2.277e-13	73.0	2911D@1|root,2ZNNZ@2|Bacteria,1P8DV@1224|Proteobacteria,2W5MI@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5823897_2	2340.JV46_13610	2.753e-08	62.0	COG0457@1|root,COG0457@2|Bacteria	2340.JV46_13610|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_5823897_0	1163617.SCD_n00738	4.453e-232	754.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
EH1_k127_5824289_1	1123392.AQWL01000003_gene195	2.309e-91	308.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,1KSYT@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
EH1_k127_5824289_2	1163617.SCD_n01481	5.768e-71	250.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
EH1_k127_5824289_3	1304883.KI912532_gene2	2.844e-52	194.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria,2KVX9@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH1_k127_5824289_0	292415.Tbd_1258	1.689e-99	334.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,1KS8U@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH1_k127_5824289_6	1123392.AQWL01000004_gene2778	8.059e-13	70.0	2EITT@1|root,3163R@2|Bacteria,1PWSX@1224|Proteobacteria,2WCBQ@28216|Betaproteobacteria,1KTDU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
EH1_k127_5824289_5	105559.Nwat_0850	1.387e-19	93.0	COG1873@1|root,COG1873@2|Bacteria,1QW30@1224|Proteobacteria	1224|Proteobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
EH1_k127_5824289_4	1120985.AUMI01000017_gene2729	2.908e-50	183.0	COG2930@1|root,COG2930@2|Bacteria,1VBSP@1239|Firmicutes,4H54G@909932|Negativicutes	909932|Negativicutes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
EH1_k127_5841234_1	1123354.AUDR01000013_gene707	6.008e-78	268.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,1KRDX@119069|Hydrogenophilales	119069|Hydrogenophilales	OT	Glutamate-ammonia ligase adenylyltransferase	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
EH1_k127_5841234_0	93220.LV28_18855	2.025e-107	354.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,1K0R8@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
EH1_k127_5860518_1	637911.AM305_02248	1.667e-27	121.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1Y9RK@135625|Pasteurellales	135625|Pasteurellales	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
EH1_k127_5860518_0	926550.CLDAP_27320	8.661e-166	538.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
EH1_k127_5860518_2	264732.Moth_2268	1.912e-07	53.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,42FBE@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
EH1_k127_5861216_0	265072.Mfla_2081	4.018e-76	266.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,2KMHI@206350|Nitrosomonadales	206350|Nitrosomonadales	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
EH1_k127_5861216_1	85643.Tmz1t_3653	9.092e-28	123.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,2KW3H@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
EH1_k127_5862607_1	864051.BurJ1DRAFT_1468	1.132e-57	209.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,1KJ77@119065|unclassified Burkholderiales	1224|Proteobacteria	P	Belongs to the ABC transporter superfamily	modC	-	3.6.3.29,3.6.3.30,3.6.3.55	ko:K02010,ko:K02017,ko:K02018,ko:K02049,ko:K02052,ko:K06857,ko:K11076,ko:K15496,ko:K15497	ko02010,ko02024,map02010,map02024	M00186,M00188,M00189,M00190,M00193,M00300,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.11.2,3.A.1.16,3.A.1.17,3.A.1.6.2,3.A.1.6.4,3.A.1.6.5,3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE,TOBE_2
EH1_k127_5862607_2	1110502.TMO_1534	1.225e-38	162.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,2JPDF@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1178 ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH1_k127_5862607_0	864051.BurJ1DRAFT_1466	3.411e-110	368.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1KK62@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	futA1	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
EH1_k127_5862607_3	404380.Gbem_1824	7.915e-18	85.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria	1224|Proteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH1_k127_5892139_0	292415.Tbd_0827	6.088e-171	544.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria,1KSG7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH1_k127_5920560_0	1122236.KB905146_gene1896	5.997e-103	342.0	COG1305@1|root,COG1305@2|Bacteria,1MVAG@1224|Proteobacteria,2VMU5@28216|Betaproteobacteria,2KNMV@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
EH1_k127_5925940_0	1123393.KB891316_gene1919	4.061e-254	805.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
EH1_k127_5925940_5	748247.AZKH_0444	3.233e-33	132.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
EH1_k127_5925940_7	1163617.SCD_n02791	6.332e-08	60.0	COG3030@1|root,COG3030@2|Bacteria,1NHHU@1224|Proteobacteria,2VX8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
EH1_k127_5925940_2	1123393.KB891330_gene846	2.14e-129	428.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1KS61@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH1_k127_5925940_4	1121035.AUCH01000008_gene1107	5.217e-86	295.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,2KUYU@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
EH1_k127_5925940_6	1163617.SCD_n00093	6.149e-26	115.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH1_k127_5925940_1	1123392.AQWL01000002_gene2019	4.3e-240	757.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KRG5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
EH1_k127_5925940_3	1485544.JQKP01000002_gene1497	5.227e-113	366.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
EH1_k127_5927072_2	1112212.JH584236_gene5	5.576e-18	85.0	COG2801@1|root,COG2801@2|Bacteria,1N39H@1224|Proteobacteria,2UCX8@28211|Alphaproteobacteria,2K52K@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
EH1_k127_5927072_3	314225.ELI_14895	8.056e-08	55.0	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2K5CA@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
EH1_k127_5927072_4	1499967.BAYZ01000099_gene4398	9.277e-05	45.0	COG1943@1|root,COG1943@2|Bacteria,2NQ84@2323|unclassified Bacteria	2|Bacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
EH1_k127_5927072_0	1125863.JAFN01000001_gene400	7.794e-248	784.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
EH1_k127_5927072_1	1125863.JAFN01000001_gene399	1.134e-107	354.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N2W@68525|delta/epsilon subdivisions,2WJRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
EH1_k127_5942148_6	666681.M301_2426	1.972e-13	82.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,2KMCV@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_5942148_1	1236959.BAMT01000002_gene2116	8.195e-142	481.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,2KMDD@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_5942148_0	582744.Msip34_0454	2.044e-196	630.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,2KM24@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
EH1_k127_5942148_5	1163617.SCD_n02492	6.98e-23	103.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
EH1_k127_5942148_2	640081.Dsui_0245	4.037e-116	391.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,2KUQH@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
EH1_k127_5942148_3	1123393.KB891331_gene2970	2.295e-42	162.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,1KS2G@119069|Hydrogenophilales	119069|Hydrogenophilales	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
EH1_k127_5942148_4	402881.Plav_1898	2.16e-25	116.0	COG0457@1|root,COG0457@2|Bacteria,1R9GZ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,DUF560,TPR_19
EH1_k127_5948_5	1159870.KB907784_gene983	1.74e-11	64.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,3T2A2@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
EH1_k127_5948_3	640081.Dsui_3338	5.171e-59	209.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
EH1_k127_5948_1	279714.FuraDRAFT_3140	1.39e-151	490.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,2KPM8@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
EH1_k127_5948_0	261292.Nit79A3_1727	1.327e-152	491.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF_2,HD
EH1_k127_5948_2	391615.ABSJ01000022_gene309	6.774e-72	264.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	ykoW	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
EH1_k127_5948_4	251229.Chro_2612	3.475e-30	137.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
EH1_k127_595595_0	395494.Galf_2780	8.802e-220	721.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,44WBX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
EH1_k127_595595_1	1163617.SCD_n00905	3.473e-26	117.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH1_k127_5978114_2	292415.Tbd_1423	1.759e-60	212.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
EH1_k127_5978114_0	1415630.U771_22565	5.24e-298	929.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
EH1_k127_5978114_1	1173024.KI912148_gene3523	5.435e-111	363.0	COG2403@1|root,COG2403@2|Bacteria,1G1FF@1117|Cyanobacteria	1117|Cyanobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
EH1_k127_5988379_1	1417296.U879_21490	7.969e-23	106.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
EH1_k127_5988379_0	1417296.U879_21490	1.179e-36	146.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
EH1_k127_5988379_2	1125863.JAFN01000001_gene3206	6.1e-08	58.0	COG2159@1|root,COG2159@2|Bacteria,1QZ3W@1224|Proteobacteria,42PKB@68525|delta/epsilon subdivisions,2WM59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
EH1_k127_6018374_2	1123392.AQWL01000004_gene2732	7.303e-11	63.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1KT0V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH1_k127_6018374_0	1123392.AQWL01000004_gene2557	1.908e-139	455.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
EH1_k127_6018374_1	1123393.KB891317_gene2264	8.115e-48	174.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria,1KSUB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
EH1_k127_6046706_4	509190.Cseg_3398	5.332e-05	45.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH1_k127_6046706_2	748247.AZKH_3667	1.235e-52	190.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,2KWM2@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH1_k127_6046706_0	292415.Tbd_2164	3.166e-172	555.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,1KRA2@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
EH1_k127_6046706_1	1123393.KB891329_gene970	3.246e-55	196.0	COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2VT6I@28216|Betaproteobacteria,1KSD1@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ferric uptake regulator family	-	-	-	ko:K09826	-	-	-	-	ko00000,ko03000	-	-	-	FUR
EH1_k127_6046706_3	292415.Tbd_0230	1.005e-25	109.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
EH1_k127_6054897_0	443143.GM18_2747	2.72e-120	404.0	COG1028@1|root,COG2070@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1NS4N@1224|Proteobacteria,42YFR@68525|delta/epsilon subdivisions,2WTVB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,PP-binding
EH1_k127_6075_0	1163617.SCD_n02117	1.422e-272	848.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
EH1_k127_6075_2	1123392.AQWL01000005_gene3246	4.652e-20	96.0	2EBVX@1|root,335VA@2|Bacteria,1PSUJ@1224|Proteobacteria,2VXJY@28216|Betaproteobacteria,1KSYQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH1_k127_6075_1	1163617.SCD_n02728	8.779e-101	348.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH1_k127_6076504_2	292415.Tbd_1222	9.161e-55	199.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH1_k127_6076504_0	1123392.AQWL01000003_gene265	5.976e-198	626.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,1KS13@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
EH1_k127_6076504_1	292415.Tbd_1220	1.019e-165	523.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,1KRGY@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
EH1_k127_6077067_1	338969.Rfer_2486	1.779e-87	310.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,1R444@1224|Proteobacteria,2VJPB@28216|Betaproteobacteria,4AGJZ@80864|Comamonadaceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HDOD
EH1_k127_6077067_0	580332.Slit_2233	3.104e-200	630.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,44UYD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
EH1_k127_6092017_1	153948.NAL212_2964	1.045e-29	130.0	28PH1@1|root,2ZC7N@2|Bacteria,1RAFS@1224|Proteobacteria,2WBZ8@28216|Betaproteobacteria,37423@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6092017_0	338969.Rfer_1747	2.126e-81	279.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VS5T@28216|Betaproteobacteria,4AJE7@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6092017_3	565045.NOR51B_2370	7.64e-16	81.0	COG2863@1|root,COG2863@2|Bacteria,1N7NU@1224|Proteobacteria,1SH3Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6092017_2	1149133.ppKF707_4672	2.793e-21	99.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
EH1_k127_6110057_1	40373.F991_00375	9.146e-96	318.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,3NT1J@468|Moraxellaceae	1236|Gammaproteobacteria	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	nasD	-	-	ko:K02049,ko:K15578	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17	-	-	ABC_tran
EH1_k127_6110057_0	1101195.Meth11DRAFT_0419	3.394e-147	481.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,2KKIU@206350|Nitrosomonadales	206350|Nitrosomonadales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
EH1_k127_6110057_2	1387312.BAUS01000002_gene210	2.516e-23	100.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,2KKMM@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
EH1_k127_6127717_3	1255043.TVNIR_0264	1.677e-63	228.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_19,TPR_2
EH1_k127_6127717_0	1163617.SCD_n02776	1.806e-149	479.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
EH1_k127_6127717_6	1123354.AUDR01000017_gene13	1.567e-42	163.0	COG3133@1|root,COG3133@2|Bacteria,1RJWY@1224|Proteobacteria,2WE8P@28216|Betaproteobacteria,1KRPZ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	17 kDa surface antigen	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	-
EH1_k127_6127717_4	1163617.SCD_n02773	2.761e-58	211.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
EH1_k127_6127717_2	1236959.BAMT01000005_gene153	2.726e-99	334.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,2KKMZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
EH1_k127_6127717_1	292415.Tbd_2508	1.166e-109	368.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1KRNZ@119069|Hydrogenophilales	119069|Hydrogenophilales	D	PP-loop family	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
EH1_k127_6127717_5	1163617.SCD_n02788	2.053e-45	170.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
EH1_k127_6130925_0	1123393.KB891331_gene2855	5.778e-241	754.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,1KRE6@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
EH1_k127_6130925_1	323848.Nmul_A0982	1.029e-92	308.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,372GN@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
EH1_k127_6133914_6	305700.B447_08114	7.597e-35	137.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
EH1_k127_6133914_4	435908.IDSA_11220	7.194e-44	176.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RZBU@1236|Gammaproteobacteria,2QGAW@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH1_k127_6133914_2	1123393.KB891316_gene1669	1.187e-76	266.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,1KSBP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
EH1_k127_6133914_1	1123392.AQWL01000005_gene3080	3.388e-87	302.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,1KRN7@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
EH1_k127_6133914_5	1485544.JQKP01000007_gene1958	5.331e-38	153.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,44VS3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
EH1_k127_6133914_3	864073.HFRIS_008391	8.937e-65	230.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,4748U@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
EH1_k127_6133914_0	1266925.JHVX01000011_gene1486	6.506e-88	306.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
EH1_k127_6133914_7	395494.Galf_2360	5.609e-27	117.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,44V40@713636|Nitrosomonadales	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
EH1_k127_6136709_3	292415.Tbd_2664	1.55e-32	137.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria	1224|Proteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
EH1_k127_6136709_0	1123393.KB891316_gene2033	3.881e-149	491.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KRAF@119069|Hydrogenophilales	119069|Hydrogenophilales	F	ATP-grasp domain	-	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
EH1_k127_6136709_2	292415.Tbd_2661	2.68e-65	228.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,1KRNW@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
EH1_k127_6136709_1	522306.CAP2UW1_2943	2.788e-136	439.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KPVU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH1_k127_6139554_1	76114.ebA5117	5.887e-49	183.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,2KUPR@206389|Rhodocyclales	206389|Rhodocyclales	T	alginate biosynthesis protein AlgZ FimS	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
EH1_k127_6139554_0	1163617.SCD_n02121	1.106e-105	355.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria	1224|Proteobacteria	E	D-Amino acid dehydrogenase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
EH1_k127_6139554_2	153948.NAL212_2900	3.493e-29	122.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,37394@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
EH1_k127_615407_2	557598.LHK_02114	3.496e-24	103.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KPZV@206351|Neisseriales	206351|Neisseriales	H	folylpolyglutamate synthase dihydrofolate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
EH1_k127_615407_0	1123392.AQWL01000001_gene1533	1.033e-135	437.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,1KRX7@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
EH1_k127_615407_1	1163617.SCD_n00884	1.095e-101	335.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
EH1_k127_6163784_0	1123393.KB891316_gene2123	3.75e-133	429.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2W9BF@28216|Betaproteobacteria,1KT6Y@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
EH1_k127_6163784_1	1123401.JHYQ01000003_gene2052	5.725e-100	331.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
EH1_k127_6167444_2	396588.Tgr7_1491	2.366e-27	114.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1WXIF@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
EH1_k127_6167444_1	85643.Tmz1t_3010	1.443e-53	205.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,2KW8Q@206389|Rhodocyclales	206389|Rhodocyclales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
EH1_k127_6167444_0	1163617.SCD_n01285	5.955e-153	507.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
EH1_k127_6196638_1	582744.Msip34_0658	4.754e-05	45.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KKM4@206350|Nitrosomonadales	206350|Nitrosomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH1_k127_6196638_0	265072.Mfla_2074	0.0	1048.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KKET@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH1_k127_6248395_0	85643.Tmz1t_3213	2.656e-95	320.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,2KU7X@206389|Rhodocyclales	206389|Rhodocyclales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
EH1_k127_6248395_3	1266909.AUAG01000039_gene155	2.885e-18	92.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg,SBP_bac_3
EH1_k127_6248395_1	1123393.KB891316_gene1308	3.148e-45	170.0	COG5001@1|root,COG5001@2|Bacteria,1PHN5@1224|Proteobacteria,2W90M@28216|Betaproteobacteria,1KS5T@119069|Hydrogenophilales	119069|Hydrogenophilales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH1_k127_6248395_2	84531.JMTZ01000094_gene646	4.228e-35	141.0	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,1S71T@1236|Gammaproteobacteria,1X7C4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6262376_2	279714.FuraDRAFT_2681	6.306e-64	224.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,2KPMJ@206351|Neisseriales	206351|Neisseriales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
EH1_k127_6262376_0	1123393.KB891331_gene2964	3.17e-184	584.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,1KRI0@119069|Hydrogenophilales	119069|Hydrogenophilales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
EH1_k127_6262376_1	1123392.AQWL01000002_gene1858	1.021e-64	227.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,1KRZC@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mur ligase family, catalytic domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH1_k127_6269036_4	1123392.AQWL01000004_gene2711	1.597e-11	66.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,1KSMT@119069|Hydrogenophilales	119069|Hydrogenophilales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
EH1_k127_6269036_0	1049564.TevJSym_ab00620	5.108e-142	462.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1J5BC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Aminotransferase class I and II	IV02_28760	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
EH1_k127_6269036_3	1123392.AQWL01000006_gene651	4.888e-41	154.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KT6E@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
EH1_k127_6269036_1	292415.Tbd_0769	4.423e-70	247.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,1KSWG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
EH1_k127_6269036_2	522306.CAP2UW1_3680	4.097e-46	169.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KQCV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH1_k127_6274411_3	1178482.BJB45_03965	1.245e-08	58.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1XI2U@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
EH1_k127_6274411_0	1163617.SCD_n02535	5.953e-129	417.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
EH1_k127_6274411_1	1123393.KB891316_gene1546	8.847e-104	341.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1KRSC@119069|Hydrogenophilales	119069|Hydrogenophilales	G	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH1_k127_6274411_2	1123392.AQWL01000005_gene2964	1.676e-59	209.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,1KS54@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH1_k127_6284088_2	1304883.KI912532_gene1531	1.752e-134	437.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,2KURY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
EH1_k127_6284088_6	1157708.KB907452_gene3974	5.405e-11	67.0	2EC4W@1|root,3363P@2|Bacteria,1N7E3@1224|Proteobacteria,2VWC7@28216|Betaproteobacteria,4AFB8@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6284088_3	56110.Oscil6304_1525	1.062e-78	268.0	COG0469@1|root,COG0469@2|Bacteria,1G2QX@1117|Cyanobacteria,1H92W@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH1_k127_6284088_5	983917.RGE_22610	4.987e-64	236.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,2VNQM@28216|Betaproteobacteria,1KJVS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH1_k127_6284088_0	1123392.AQWL01000003_gene399	8.085e-139	446.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KSBR@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
EH1_k127_6284088_1	1123393.KB891327_gene372	2.361e-137	441.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KRK6@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH1_k127_6284088_4	1123392.AQWL01000003_gene401	8.689e-72	244.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KS4M@119069|Hydrogenophilales	119069|Hydrogenophilales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH1_k127_6311817_0	292415.Tbd_0338	6.026e-239	742.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KSCE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
EH1_k127_6311817_7	748280.NH8B_3836	9.473e-59	209.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,2KQCS@206351|Neisseriales	206351|Neisseriales	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
EH1_k127_6311817_5	292415.Tbd_0336	3.366e-64	223.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria,1KSDE@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
EH1_k127_6311817_6	1038869.AXAN01000007_gene5769	5.99e-63	235.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,1K4CH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
EH1_k127_6311817_3	1120999.JONM01000002_gene566	4.27e-91	316.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales	206351|Neisseriales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
EH1_k127_6311817_4	1163617.SCD_n02664	9.101e-65	229.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria	28216|Betaproteobacteria	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
EH1_k127_6311817_1	1163617.SCD_n02665	1.036e-145	472.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_6311817_2	76114.ebA1066	3.261e-138	444.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,2KUW8@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
EH1_k127_6346235_1	335283.Neut_0898	3.857e-10	62.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,3724P@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
EH1_k127_6346235_0	765911.Thivi_3680	1.232e-236	742.0	COG0367@1|root,COG0367@2|Bacteria,1PRFK@1224|Proteobacteria,1RNBE@1236|Gammaproteobacteria,1WW7I@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH1_k127_637301_1	266264.Rmet_4620	4.042e-55	199.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2VZSW@28216|Betaproteobacteria,1K5Z2@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH1_k127_637301_2	1458357.BG58_09880	1.866e-42	165.0	2E56P@1|root,32ZZD@2|Bacteria,1PYIM@1224|Proteobacteria,2W0YN@28216|Betaproteobacteria,1KATT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3302
EH1_k127_637301_3	909663.KI867149_gene3179	1.855e-13	71.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2MR97@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
EH1_k127_637301_0	1454004.AW11_03084	4.85e-108	358.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
EH1_k127_6391705_2	1301098.PKB_0545	6.101e-76	257.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
EH1_k127_6391705_1	580332.Slit_0042	4.222e-91	307.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,44V3F@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
EH1_k127_6391705_0	292415.Tbd_2044	2.968e-257	817.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KRHF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Putative metal-binding domain of cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
EH1_k127_6399379_0	1163617.SCD_n00300	5.136e-81	271.0	2DS8H@1|root,32USH@2|Bacteria,1RCDN@1224|Proteobacteria,2W06A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
EH1_k127_6399379_1	1487953.JMKF01000008_gene6044	2.961e-61	216.0	COG3803@1|root,COG3803@2|Bacteria,1G55K@1117|Cyanobacteria,1HAXI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
EH1_k127_6399379_2	1000565.METUNv1_02160	5.591e-52	189.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria,2M011@206389|Rhodocyclales	206389|Rhodocyclales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
EH1_k127_6399421_0	292415.Tbd_0990	3.693e-174	551.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1KRJA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
EH1_k127_6399421_1	292415.Tbd_0989	2.971e-143	467.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,1KS05@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH1_k127_6402588_2	1071679.BG57_10360	1.165e-49	192.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
EH1_k127_6402588_0	765910.MARPU_12065	4.057e-89	303.0	COG1752@1|root,COG1752@2|Bacteria,1R4TX@1224|Proteobacteria,1RP66@1236|Gammaproteobacteria,1X0EE@135613|Chromatiales	135613|Chromatiales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
EH1_k127_6402588_1	292415.Tbd_1512	1.762e-60	213.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,1KS4G@119069|Hydrogenophilales	119069|Hydrogenophilales	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
EH1_k127_6407723_1	1123368.AUIS01000001_gene2021	6.534e-81	275.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,2ND1R@225057|Acidithiobacillales	225057|Acidithiobacillales	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
EH1_k127_6407723_0	1288494.EBAPG3_20760	7.286e-98	333.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2VTN7@28216|Betaproteobacteria,372A7@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
EH1_k127_6407723_2	1163617.SCD_n01089	3.404e-80	273.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
EH1_k127_6407723_3	765911.Thivi_3187	0.000958	45.0	COG0369@1|root,COG0369@2|Bacteria,1NCKQ@1224|Proteobacteria,1RR4U@1236|Gammaproteobacteria,1WX7N@135613|Chromatiales	135613|Chromatiales	P	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.8.1.2	ko:K00380,ko:K02641	ko00195,ko00920,ko01100,ko01120,map00195,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
EH1_k127_6409526_0	1163617.SCD_n01830	5.477e-83	285.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
EH1_k127_6409526_1	640081.Dsui_2222	4.98e-60	218.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
EH1_k127_6409526_2	1123368.AUIS01000005_gene428	0.000194	46.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,1T4NK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
EH1_k127_6425324_6	1123392.AQWL01000005_gene3234	3.378e-68	239.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6425324_3	292415.Tbd_2489	2.261e-156	496.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KSA5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH1_k127_6425324_10	292415.Tbd_2488	1.8e-43	163.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH1_k127_6425324_11	1123392.AQWL01000005_gene3231	4.017e-42	162.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria,1KSNR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
EH1_k127_6425324_13	1485544.JQKP01000005_gene311	2.312e-13	73.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria,44WK7@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6425324_1	292415.Tbd_2485	3.596e-240	748.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,1KSCU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH1_k127_6425324_2	1123393.KB891316_gene1850	1.429e-228	709.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,1KSR2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH1_k127_6425324_7	765913.ThidrDRAFT_2034	2.558e-66	228.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1WY2D@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein TusD DsrE	dsrE	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
EH1_k127_6425324_9	292415.Tbd_2482	5.245e-55	195.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
EH1_k127_6425324_12	1123393.KB891316_gene1847	5.416e-40	150.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
EH1_k127_6425324_8	1123392.AQWL01000005_gene3224	1.244e-56	198.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH1_k127_6425324_4	292415.Tbd_2479	1.699e-113	372.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
EH1_k127_6425324_0	292415.Tbd_2478	1.168e-278	861.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,2VNTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
EH1_k127_6425324_5	292415.Tbd_2477	1.198e-108	355.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
EH1_k127_6425430_4	1123354.AUDR01000016_gene1294	5.904e-06	56.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,1KRB4@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
EH1_k127_6425430_1	1000565.METUNv1_03841	1.167e-70	249.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,2M03Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Alginate biosynthesis regulatory protein AlgR	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
EH1_k127_6425430_3	1163617.SCD_n02799	4.112e-31	129.0	COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,2WGR9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF836,Thioredoxin_2,Thioredoxin_7
EH1_k127_6425430_0	1121004.ATVC01000023_gene288	5.502e-127	413.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,2KQ5K@206351|Neisseriales	206351|Neisseriales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
EH1_k127_6425430_2	1485544.JQKP01000002_gene1608	5.357e-41	158.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,44VS4@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
EH1_k127_6447423_0	1163617.SCD_n01958	3.282e-203	647.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
EH1_k127_6447423_5	207954.MED92_10439	1.548e-36	147.0	COG2703@1|root,COG2703@2|Bacteria,1N1XS@1224|Proteobacteria,1SAVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	hemerythrin-like metal-binding	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
EH1_k127_6447423_3	1123393.KB891330_gene831	5.987e-81	275.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,1KRMP@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Biotin/lipoate A/B protein ligase family	-	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
EH1_k127_6447423_4	1123392.AQWL01000002_gene2030	1.139e-36	139.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,1KTD2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
EH1_k127_6447423_2	62928.azo0181	5.963e-112	369.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,2KVN6@206389|Rhodocyclales	206389|Rhodocyclales	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
EH1_k127_6447423_1	85643.Tmz1t_0242	2.583e-145	467.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,2KVFQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
EH1_k127_6452780_2	1089551.KE386572_gene2534	1.984e-26	109.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
EH1_k127_6452780_1	1123393.KB891316_gene1276	7.418e-141	454.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,1KRK5@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
EH1_k127_6452780_0	1232683.ADIMK_1477	5.178e-156	498.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
EH1_k127_6452780_3	667632.KB890187_gene3020	1.054e-15	76.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1K19M@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
EH1_k127_6473386_1	1163617.SCD_n00905	2.04e-11	67.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH1_k127_6473386_0	743836.AYNA01000017_gene2715	3.235e-44	183.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWK2@28211|Alphaproteobacteria,3700W@31993|Methylocystaceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
EH1_k127_6480120_0	1163617.SCD_n02541	3.58e-64	226.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH1_k127_6480120_1	1163617.SCD_n02540	2.936e-24	108.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VU7B@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
EH1_k127_6482846_0	497321.C664_02195	5.728e-29	121.0	COG3109@1|root,COG3109@2|Bacteria,1PS29@1224|Proteobacteria,2VU30@28216|Betaproteobacteria,2KWZI@206389|Rhodocyclales	206389|Rhodocyclales	T	activator of osmoprotectant transporter ProP	proQ	-	-	ko:K03607	-	-	-	-	ko00000	-	-	-	ProQ
EH1_k127_6490963_1	1123392.AQWL01000012_gene2460	4.025e-113	369.0	COG1028@1|root,COG1028@2|Bacteria	1123392.AQWL01000012_gene2460|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6490963_0	62928.azo0122	7.436e-117	394.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,2KV68@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
EH1_k127_6514052_2	1190603.AJYD01000041_gene2640	4.48e-10	69.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1XXSJ@135623|Vibrionales	135623|Vibrionales	C	COG2863 Cytochrome c553	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_6514052_1	330214.NIDE0437	3.584e-26	117.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
EH1_k127_6514052_0	159087.Daro_1851	1.086e-126	411.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
EH1_k127_6519917_1	1123392.AQWL01000002_gene1962	2.815e-119	391.0	COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,2WGG8@28216|Betaproteobacteria,1KSXE@119069|Hydrogenophilales	119069|Hydrogenophilales	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6519917_0	1123393.KB891331_gene2858	1.974e-197	634.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,2VR9V@28216|Betaproteobacteria,1KSRS@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Adenylylsulphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
EH1_k127_6539278_0	1123393.KB891330_gene761	2.023e-192	602.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KSCE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
EH1_k127_6539278_2	292415.Tbd_0339	8.543e-125	402.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KRX9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
EH1_k127_6539278_3	1123393.KB891330_gene759	1.309e-17	85.0	2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,2VXSI@28216|Betaproteobacteria,1KTEY@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
EH1_k127_6539278_1	1123393.KB891330_gene758	9.599e-127	411.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KSC5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixP_N
EH1_k127_6546135_2	1123393.KB891327_gene382	2.949e-169	537.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1KR9S@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3
EH1_k127_6546135_1	1123392.AQWL01000003_gene391	1.059e-241	750.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,1KS1J@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
EH1_k127_6546135_6	1123393.KB891327_gene380	3.771e-74	259.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,1KS1X@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
EH1_k127_6546135_0	1123393.KB891327_gene379	1.586e-251	779.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,1KREK@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
EH1_k127_6546135_5	882378.RBRH_02526	1.956e-87	292.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
EH1_k127_6546135_4	1112274.KI911560_gene1989	1.216e-97	319.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,2KKS7@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
EH1_k127_6546135_7	1131553.JIBI01000007_gene1197	1.022e-63	219.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,3737D@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
EH1_k127_6546135_8	1123392.AQWL01000003_gene397	3.881e-32	128.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,1KRV7@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
EH1_k127_6546135_3	292415.Tbd_1140	7.01e-115	374.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KRM4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
EH1_k127_6546135_9	640081.Dsui_2328	2.665e-28	115.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,2KUX6@206389|Rhodocyclales	206389|Rhodocyclales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
EH1_k127_6548905_0	1123392.AQWL01000006_gene575	1.312e-212	663.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1KRCT@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
EH1_k127_6548905_1	1123393.KB891316_gene2085	2.84e-84	287.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,1KRWY@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Ribosomal RNA adenine dimethylase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH1_k127_6548905_2	1158146.KB907126_gene1490	2.137e-39	149.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_6548905_3	1123392.AQWL01000006_gene572	4.981e-11	67.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KS7I@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
EH1_k127_6554433_3	1236959.BAMT01000005_gene103	4.236e-49	180.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,2KKJW@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
EH1_k127_6554433_6	1500281.JQKZ01000015_gene2145	7.47e-05	47.0	2AAAU@1|root,30ZKF@2|Bacteria,4PDWW@976|Bacteroidetes,1IEA8@117743|Flavobacteriia,3ZT19@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6554433_2	580332.Slit_1234	1.714e-58	211.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
EH1_k127_6554433_5	1304883.KI912532_gene2486	3.254e-33	136.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,2KWUE@206389|Rhodocyclales	206389|Rhodocyclales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
EH1_k127_6554433_0	1123392.AQWL01000004_gene2563	1.971e-153	497.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KRAB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
EH1_k127_6554433_1	1123392.AQWL01000004_gene2564	6.858e-99	340.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria,1KRTJ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
EH1_k127_6554433_4	640081.Dsui_2320	2.031e-41	169.0	28I8W@1|root,2Z8BP@2|Bacteria,1N0SC@1224|Proteobacteria,2VK0J@28216|Betaproteobacteria,2KVDQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2863
EH1_k127_6561123_1	335283.Neut_1176	2.602e-193	606.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,373TP@32003|Nitrosomonadales	28216|Betaproteobacteria	F	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
EH1_k127_6561123_2	1123392.AQWL01000006_gene678	3.234e-83	289.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,1KSQ3@119069|Hydrogenophilales	119069|Hydrogenophilales	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
EH1_k127_6561123_0	1123393.KB891316_gene1940	8.447e-210	666.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,1KS9B@119069|Hydrogenophilales	119069|Hydrogenophilales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
EH1_k127_6567162_3	640081.Dsui_0805	5.268e-12	69.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,2KVAV@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
EH1_k127_6567162_2	1485544.JQKP01000011_gene741	4.663e-111	379.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,44VJM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
EH1_k127_6567162_0	765911.Thivi_2177	3.89e-190	599.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1WX0M@135613|Chromatiales	135613|Chromatiales	GM	Male sterility protein	-	-	5.1.3.7	ko:K02473	ko00520,ko01100,map00520,map01100	-	R00418	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
EH1_k127_6567162_1	1123393.KB891316_gene1088	5.179e-154	488.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,1KRD7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
EH1_k127_6580218_3	859657.RPSI07_3369	3.39e-30	130.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,1JZRN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
EH1_k127_6580218_4	1123393.KB891317_gene2354	1.444e-21	99.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria,1KTEJ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
EH1_k127_6580218_0	1304883.KI912532_gene1377	0.0	1059.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KUGX@206389|Rhodocyclales	206389|Rhodocyclales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
EH1_k127_6580218_1	1266925.JHVX01000022_gene1763	1.276e-162	524.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
EH1_k127_6580218_2	1286631.X805_14920	4.897e-36	138.0	COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,2VVIP@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6582337_3	118173.KB235914_gene2172	1.259e-31	129.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_24,TylF
EH1_k127_6582337_1	395495.Lcho_0484	3.758e-80	274.0	COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
EH1_k127_6582337_2	395495.Lcho_0484	1.181e-40	166.0	COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
EH1_k127_6582337_0	237609.PSAKL28_25280	1.794e-159	509.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF2	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
EH1_k127_6593080_0	795666.MW7_0760	3.686e-130	425.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH1_k127_6593080_1	1121351.AUAP01000012_gene1247	1.7e-45	172.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
EH1_k127_6624587_2	1123393.KB891317_gene2468	9.064e-31	121.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria,1KSSF@119069|Hydrogenophilales	119069|Hydrogenophilales	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
EH1_k127_6624587_1	1163617.SCD_n01884	7.48e-146	467.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
EH1_k127_6624587_0	292415.Tbd_0577	0.0	1475.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,1KRA3@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Valyl tRNA synthetase tRNA binding arm	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH1_k127_6626307_6	1123368.AUIS01000014_gene2319	2.73e-40	164.0	COG1807@1|root,COG1807@2|Bacteria,1RE4T@1224|Proteobacteria,1S5IF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
EH1_k127_6626307_1	292415.Tbd_1550	7.751e-130	421.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1KRCS@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
EH1_k127_6626307_3	1123393.KB891333_gene2577	9.468e-107	351.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KS53@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH1_k127_6626307_7	1236959.BAMT01000001_gene1638	6.722e-34	131.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KN5P@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
EH1_k127_6626307_0	62928.azo1627	6.424e-232	721.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,2KUW2@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
EH1_k127_6626307_4	519989.ECTPHS_03227	3.995e-68	241.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
EH1_k127_6626307_2	1485544.JQKP01000013_gene1819	1.143e-110	366.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,44VGR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
EH1_k127_6626307_5	265072.Mfla_1500	6.013e-56	213.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,2KKXE@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
EH1_k127_6628425_6	1128912.GMES_2948	5.842e-05	50.0	COG3385@1|root,COG3385@2|Bacteria,1QR0Q@1224|Proteobacteria,1RTSH@1236|Gammaproteobacteria,46C59@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6628425_0	1123393.KB891326_gene136	0.0	1067.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,1KSIG@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
EH1_k127_6628425_4	580332.Slit_1618	1.076e-38	150.0	2AB8D@1|root,310NU@2|Bacteria,1RFGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6628425_1	1123392.AQWL01000003_gene141	2.065e-245	761.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
EH1_k127_6628425_3	1123392.AQWL01000003_gene142	1.136e-116	377.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria,1KSBB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6628425_2	1123393.KB891326_gene133	1.321e-151	482.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,1KRZI@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH1_k127_6657452_6	1149133.ppKF707_1768	1.244e-07	54.0	COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,1SA20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
EH1_k127_6657452_2	1123392.AQWL01000014_gene797	1.19e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KTB5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
EH1_k127_6657452_0	1123392.AQWL01000008_gene1189	2.052e-219	685.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1KS2Q@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
EH1_k127_6657452_1	1123392.AQWL01000008_gene1190	1.585e-110	363.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1KRBX@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Sec-independent protein translocase protein (TatC)	-	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
EH1_k127_6657452_4	62928.azo3339	1.198e-21	100.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH1_k127_6657452_3	292415.Tbd_1704	1.054e-22	99.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KTFE@119069|Hydrogenophilales	119069|Hydrogenophilales	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH1_k127_6657452_5	1163617.SCD_n00594	3.342e-21	93.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
EH1_k127_6667595_0	1123392.AQWL01000003_gene506	3.716e-309	952.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,1KS41@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
EH1_k127_6674118_1	1121035.AUCH01000039_gene1728	3.296e-68	239.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH1_k127_6674118_0	159087.Daro_0729	1.185e-116	382.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH1_k127_671384_2	1454004.AW11_02710	4.195e-80	278.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1KQ5X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
EH1_k127_671384_1	1163617.SCD_n01159	1.377e-120	391.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH1_k127_671384_3	1123392.AQWL01000003_gene417	6.542e-66	230.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2WGE2@28216|Betaproteobacteria,1KSQD@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH1_k127_671384_6	1123393.KB891317_gene2194	0.0008835	45.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,1KSQR@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
EH1_k127_671384_5	62928.azo1464	7.259e-08	53.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,2KV4P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
EH1_k127_671384_0	243231.GSU0946	5.144e-129	437.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43SWK@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	sensor diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0700	EAL,GGDEF,HAMP,PAS_4,PAS_9
EH1_k127_671384_4	1163617.SCD_n01212	8.78e-39	148.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VKS0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_6717771_0	99598.Cal7507_3737	9.151e-245	780.0	COG3299@1|root,COG3299@2|Bacteria,1G3VV@1117|Cyanobacteria	1117|Cyanobacteria	S	protein, phage tail-like region	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
EH1_k127_6717771_1	99598.Cal7507_3738	1.418e-77	267.0	COG3299@1|root,COG3299@2|Bacteria,1G6U3@1117|Cyanobacteria	1117|Cyanobacteria	T	protein, phage tail-like region	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,Sortilin-Vps10
EH1_k127_6732145_0	1123392.AQWL01000003_gene175	0.0	1026.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH1_k127_6732145_1	1163617.SCD_n00983	1.883e-49	182.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
EH1_k127_673435_0	1123392.AQWL01000006_gene684	1.892e-124	413.0	COG0784@1|root,COG2770@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2770@2|Bacteria,COG4251@2|Bacteria,1QTVB@1224|Proteobacteria,2WHE1@28216|Betaproteobacteria,1KSTV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
EH1_k127_673435_1	265072.Mfla_1099	1.857e-86	290.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,2KKJY@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH1_k127_6736481_0	1163617.SCD_n00818	2.202e-297	917.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH1_k127_6736481_5	314607.KB13_289	5.032e-74	262.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KPXQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Acetolactate synthase I III small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
EH1_k127_6736481_2	1304883.KI912532_gene3080	8.608e-191	598.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,2KUKK@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
EH1_k127_6736481_4	1163617.SCD_n00821	4.986e-99	327.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
EH1_k127_6736481_3	1123392.AQWL01000001_gene1479	8.908e-106	349.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1KRAD@119069|Hydrogenophilales	119069|Hydrogenophilales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
EH1_k127_6736481_1	1163617.SCD_n00823	1.024e-283	876.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
EH1_k127_6736481_8	686340.Metal_0082	6.862e-22	108.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria,1XFCG@135618|Methylococcales	135618|Methylococcales	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_6736481_10	1116472.MGMO_43c00280	6.488e-16	90.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria,1XFCG@135618|Methylococcales	135618|Methylococcales	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_6736481_6	314345.SPV1_01487	1.348e-55	203.0	293CN@1|root,2ZQV6@2|Bacteria,1RDZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6736481_7	398578.Daci_4967	7.964e-40	152.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,4AECU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
EH1_k127_6736481_9	1158292.JPOE01000005_gene718	1.343e-18	87.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2VS07@28216|Betaproteobacteria,1KMUT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Protein of unknown function (DUF2470)	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
EH1_k127_6740976_2	1123354.AUDR01000013_gene743	3.833e-08	54.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,1KRIQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
EH1_k127_6740976_0	1132855.KB913035_gene283	1.047e-214	676.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,2KM06@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
EH1_k127_6740976_1	1123393.KB891330_gene898	1.005e-96	326.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,1KSVB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
EH1_k127_6786207_1	1458357.BG58_09875	6.746e-81	276.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2VZSW@28216|Betaproteobacteria,1K5Z2@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH1_k127_6786207_0	1458357.BG58_09870	5.259e-115	387.0	COG1538@1|root,COG1538@2|Bacteria,1REC6@1224|Proteobacteria,2VZ9S@28216|Betaproteobacteria,1KBKV@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_6805422_2	395495.Lcho_3373	6.726e-44	162.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,1KJ7W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
EH1_k127_6805422_1	1123393.KB891317_gene2379	1.406e-107	360.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,1KRGJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
EH1_k127_6805422_3	580332.Slit_0704	3.246e-17	85.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,44W3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
EH1_k127_6805422_4	1217718.ALOU01000071_gene5062	6.682e-05	55.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,2VRHM@28216|Betaproteobacteria,1K4AB@119060|Burkholderiaceae	28216|Betaproteobacteria	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
EH1_k127_6805422_0	265072.Mfla_2322	1.026e-177	561.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KM37@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH1_k127_6853128_0	535289.Dtpsy_0106	0.0	1032.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,2VJYM@28216|Betaproteobacteria,4ABIQ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
EH1_k127_6853128_3	1123367.C666_09125	3.166e-20	92.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
EH1_k127_6853128_1	1123392.AQWL01000005_gene2906	1.778e-72	252.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VQMN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	anaerobic ribonucleoside-triphosphate reductase activating protein	nrdG	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
EH1_k127_6853128_2	1123392.AQWL01000005_gene2915	1.693e-49	180.0	COG2191@1|root,COG2191@2|Bacteria,1RD60@1224|Proteobacteria,2VR8B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
EH1_k127_6858572_1	768671.ThimaDRAFT_3684	2.484e-26	111.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria,1WYYP@135613|Chromatiales	135613|Chromatiales	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
EH1_k127_6858572_0	1121405.dsmv_0890	6.049e-203	644.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
EH1_k127_6888560_2	292415.Tbd_1427	9.785e-87	314.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VJC7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
EH1_k127_6888560_1	1123392.AQWL01000008_gene1249	3.967e-140	450.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VN77@28216|Betaproteobacteria,1KS6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH1_k127_6888560_0	1123393.KB891329_gene945	4.108e-144	458.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,1KSTF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
EH1_k127_68907_5	1121022.ABENE_14850	1.887e-05	55.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH1_k127_68907_3	1304883.KI912532_gene2637	1.217e-17	84.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VW0H@28216|Betaproteobacteria,2KXHW@206389|Rhodocyclales	206389|Rhodocyclales	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
EH1_k127_68907_0	1163617.SCD_n01376	3.004e-123	401.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
EH1_k127_68907_1	1502770.JQMG01000001_gene65	7.003e-118	389.0	28IX1@1|root,2ZC5T@2|Bacteria,1R35E@1224|Proteobacteria,2VQUH@28216|Betaproteobacteria,2KKKU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
EH1_k127_68907_6	866536.Belba_0492	0.0004311	48.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,47M22@768503|Cytophagia	976|Bacteroidetes	L	PFAM Eco57I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
EH1_k127_68907_2	1123255.JHYS01000002_gene2515	1.325e-40	151.0	COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,2VV9F@28216|Betaproteobacteria,4AG2J@80864|Comamonadaceae	28216|Betaproteobacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
EH1_k127_68907_4	1162668.LFE_1276	4.423e-12	69.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
EH1_k127_6916024_0	1163617.SCD_n00279	6.347e-263	818.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH1_k127_6916024_1	1283300.ATXB01000001_gene514	2.063e-38	146.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XFA7@135618|Methylococcales	135618|Methylococcales	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
EH1_k127_6966127_0	316067.Geob_0643	1.761e-72	254.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
EH1_k127_6966127_1	909663.KI867150_gene1970	9.102e-36	139.0	COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,42UAH@68525|delta/epsilon subdivisions,2WQUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellar FlbT family protein	flbT	-	-	ko:K06601	-	-	-	-	ko00000,ko02035	-	-	-	FlbT
EH1_k127_6966127_2	338966.Ppro_3335	1.074e-28	119.0	COG5442@1|root,COG5442@2|Bacteria,1REZ8@1224|Proteobacteria,42W1U@68525|delta/epsilon subdivisions,2WRE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar protein FlaF	-	-	-	ko:K06602	-	-	-	-	ko00000,ko02035	-	-	-	FlaF
EH1_k127_6966127_4	1163617.SCD_n01644	7.104e-07	57.0	2EQYD@1|root,33II1@2|Bacteria,1NHV5@1224|Proteobacteria,2VXZK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
EH1_k127_6966127_3	375286.mma_1445	3.648e-07	62.0	COG3144@1|root,COG3144@2|Bacteria,1N0CE@1224|Proteobacteria,2VQG2@28216|Betaproteobacteria,4748E@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Flagellar hook-length control protein FliK	fliK1	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
EH1_k127_6966127_5	322710.Avin_24280	5.942e-05	55.0	COG3144@1|root,COG3144@2|Bacteria,1RIQS@1224|Proteobacteria,1SD8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
EH1_k127_6976561_1	1123392.AQWL01000014_gene801	1.504e-73	252.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
EH1_k127_6976561_0	1123392.AQWL01000014_gene802	1.413e-199	629.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
EH1_k127_6976561_2	1121035.AUCH01000004_gene298	8.616e-21	96.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KXFI@206389|Rhodocyclales	206389|Rhodocyclales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH1_k127_698643_1	404380.Gbem_1815	6.343e-155	496.0	COG1657@1|root,COG1657@2|Bacteria,1RDNW@1224|Proteobacteria,42S7H@68525|delta/epsilon subdivisions,2WNQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
EH1_k127_698643_0	443144.GM21_2434	8.978e-157	504.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WK58@28221|Deltaproteobacteria,43W1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	3-dehydroquinate synthase	aroB	-	4.2.3.152,4.2.3.4	ko:K01735,ko:K19969	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R03083,R10937	RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH1_k127_6987329_2	1158760.AQXP01000052_gene1713	7.667e-18	87.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH1_k127_6987329_0	264198.Reut_B4852	1.493e-105	354.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,2VN09@28216|Betaproteobacteria,1K3TX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
EH1_k127_6987329_1	583345.Mmol_1784	6.879e-94	315.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria	1224|Proteobacteria	G	phosphomannomutase	noeK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH1_k127_6990352_5	292415.Tbd_1099	5.225e-15	76.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,1KRGD@119069|Hydrogenophilales	119069|Hydrogenophilales	M	NlpB/DapX lipoprotein	-	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
EH1_k127_6990352_0	292415.Tbd_1098	5.49e-136	438.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,1KS9J@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
EH1_k127_6990352_2	1458357.BG58_11590	3.179e-53	192.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
EH1_k127_6990352_1	335283.Neut_2061	9.886e-59	217.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,37217@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
EH1_k127_6990352_4	1247649.D560_3538	5.772e-25	109.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria,3T4FK@506|Alcaligenaceae	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
EH1_k127_6990352_3	1123326.JFBL01000010_gene687	7.414e-26	107.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2YMJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
EH1_k127_6994643_0	522306.CAP2UW1_1855	1.686e-87	298.0	COG0725@1|root,COG0725@2|Bacteria,1QD9D@1224|Proteobacteria,2VPYH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
EH1_k127_6994643_1	765911.Thivi_1743	5.845e-31	128.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
EH1_k127_6995884_5	946483.Cenrod_1789	3.782e-14	73.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,2VQ6H@28216|Betaproteobacteria,4AIZE@80864|Comamonadaceae	28216|Betaproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
EH1_k127_6995884_1	395494.Galf_2353	4.34e-133	441.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,44V12@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
EH1_k127_6995884_0	1123393.KB891316_gene1111	3.469e-162	522.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSDB@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH1_k127_6995884_2	1120999.JONM01000006_gene2508	8.86e-104	357.0	COG4191@1|root,COG4191@2|Bacteria,1QU7R@1224|Proteobacteria,2VICU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Signal transduction histidine kinase	pilS	-	2.7.13.3	ko:K02668,ko:K10125	ko02020,map02020	M00501,M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
EH1_k127_6995884_6	1123392.AQWL01000001_gene1608	6.164e-11	65.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,1KTER@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6995884_4	1163617.SCD_n01880	2.297e-26	112.0	2E5B5@1|root,33039@2|Bacteria,1NDK8@1224|Proteobacteria,2W5JF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_6995884_3	1349767.GJA_94	7.753e-76	268.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria,477P6@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
EH1_k127_6995884_7	1317122.ATO12_12685	0.0001651	44.0	COG2730@1|root,COG3250@1|root,COG4733@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,F5_F8_type_C,fn3
EH1_k127_7000783_2	1123392.AQWL01000002_gene1954	5.538e-85	289.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,1KRQU@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
EH1_k127_7000783_0	1163617.SCD_n02940	5.68e-260	822.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
EH1_k127_7000783_3	1304883.KI912532_gene1078	4.557e-27	118.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,2KUIR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7000783_1	292415.Tbd_0199	5.08e-146	476.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Sugar transferase	wcaJ	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3
EH1_k127_7029758_4	330214.NIDE0065	3.578e-53	189.0	29X4J@1|root,30ITG@2|Bacteria,3J1BS@40117|Nitrospirae	40117|Nitrospirae	S	MerT mercuric transport protein	merT	-	-	ko:K08363	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	MerT
EH1_k127_7029758_7	887898.HMPREF0551_1415	2.749e-28	123.0	COG2608@1|root,COG2608@2|Bacteria,1N95B@1224|Proteobacteria,2VSRA@28216|Betaproteobacteria,1K9UM@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein	merP	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
EH1_k127_7029758_5	330214.NIDE0067	1.254e-40	153.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7029758_0	1163617.SCD_n01489	3.926e-259	806.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
EH1_k127_7029758_6	566466.NOR53_3671	2.621e-34	136.0	COG2119@1|root,COG2119@2|Bacteria,1N85A@1224|Proteobacteria,1SAAX@1236|Gammaproteobacteria,1JB92@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
EH1_k127_7029758_1	1163617.SCD_n01490	3.107e-200	629.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
EH1_k127_7029758_2	1163617.SCD_n01491	9.481e-153	487.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
EH1_k127_7029758_3	395494.Galf_0004	7.23e-96	316.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
EH1_k127_7044785_1	640081.Dsui_1224	1.494e-119	389.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH1_k127_7044785_6	1163617.SCD_n00054	2.1e-29	123.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
EH1_k127_7044785_2	1163617.SCD_n00055	1.547e-92	316.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
EH1_k127_7044785_0	292415.Tbd_2442	4.808e-232	730.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1KS2N@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
EH1_k127_7044785_3	1121035.AUCH01000006_gene680	4.26e-65	231.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KW3W@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
EH1_k127_7044785_4	640081.Dsui_0452	1.401e-37	149.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,2KWQI@206389|Rhodocyclales	206389|Rhodocyclales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
EH1_k127_7044785_5	1163617.SCD_n02080	6.264e-35	139.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7046054_0	292415.Tbd_1266	2.093e-171	549.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH1_k127_7054140_1	1123393.KB891326_gene65	6.838e-112	372.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,2VNEE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
EH1_k127_7054140_0	1123393.KB891326_gene66	1.456e-155	497.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2VJP0@28216|Betaproteobacteria,1KS9Q@119069|Hydrogenophilales	119069|Hydrogenophilales	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
EH1_k127_7054822_0	1499967.BAYZ01000016_gene6563	7.165e-134	449.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
EH1_k127_7065728_0	1123393.KB891328_gene629	1.074e-156	499.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,1KRXB@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
EH1_k127_7065728_1	292415.Tbd_0589	5.411e-94	324.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,1KRQD@119069|Hydrogenophilales	119069|Hydrogenophilales	D	TilS substrate binding domain	-	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
EH1_k127_7065728_2	1121004.ATVC01000020_gene30	6.282e-12	67.0	COG3147@1|root,COG3147@2|Bacteria,1QYE8@1224|Proteobacteria,2WHED@28216|Betaproteobacteria,2KRYS@206351|Neisseriales	206351|Neisseriales	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH1_k127_7068011_1	880073.Calab_0133	2.563e-58	225.0	COG0860@1|root,COG1361@1|root,COG3858@1|root,COG0860@2|Bacteria,COG1361@2|Bacteria,COG3858@2|Bacteria,2NQII@2323|unclassified Bacteria	2|Bacteria	M	Glyco_18	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K20276	ko00550,ko01100,ko01502,ko01503,ko02020,ko02024,map00550,map01100,map01502,map01503,map02020,map02024	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_18,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
EH1_k127_7068011_2	186497.PF0548	1.328e-20	93.0	COG0298@1|root,arCOG04427@2157|Archaea,2Y0AJ@28890|Euryarchaeota,244KI@183968|Thermococci	183968|Thermococci	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH1_k127_7068011_0	635013.TherJR_1302	7.719e-62	224.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,2605Y@186807|Peptococcaceae	186801|Clostridia	O	Hydrogenase expression formation protein hypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
EH1_k127_7088719_2	1123392.AQWL01000009_gene1115	1.074e-116	377.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PUA-like domain	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PK,PUA_2
EH1_k127_7088719_4	1163617.SCD_n01732	1.01e-53	197.0	28JUM@1|root,2Z9JN@2|Bacteria,1NDV6@1224|Proteobacteria,2VJ3P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7088719_1	398767.Glov_0812	3.473e-129	417.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
EH1_k127_7088719_6	983917.RGE_33840	2.326e-19	90.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,1KM0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH1_k127_7088719_5	1163617.SCD_n02383	2.595e-21	95.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH1_k127_7088719_0	1163617.SCD_n01218	3.04e-138	450.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH1_k127_7088719_3	1163617.SCD_n01219	6.417e-59	207.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH1_k127_7101292_4	1051501.AYTL01000030_gene3156	0.0002643	43.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7101292_2	1163617.SCD_n01217	7.357e-58	205.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
EH1_k127_7101292_0	1249627.D779_3818	1.542e-114	376.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
EH1_k127_7101292_3	522306.CAP2UW1_3335	1.83e-32	126.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,1KQY2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
EH1_k127_7101292_1	1485544.JQKP01000004_gene565	3.511e-59	225.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,44VIR@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
EH1_k127_7118722_4	631362.Thi970DRAFT_04902	8.365e-11	69.0	2BXQF@1|root,32R1T@2|Bacteria,1RJTZ@1224|Proteobacteria,1SUVI@1236|Gammaproteobacteria,1X1W6@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	-
EH1_k127_7118722_1	631362.Thi970DRAFT_04903	2.19e-72	250.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,1S6H0@1236|Gammaproteobacteria,1WX9R@135613|Chromatiales	135613|Chromatiales	P	PFAM Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
EH1_k127_7118722_0	123214.PERMA_0831	8.49e-110	372.0	28N7F@1|root,2ZBC4@2|Bacteria,2G4MS@200783|Aquificae	200783|Aquificae	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
EH1_k127_7118722_3	1123325.JHUV01000008_gene643	4.017e-30	124.0	COG5266@1|root,COG5266@2|Bacteria,2G51V@200783|Aquificae	200783|Aquificae	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K16915	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	-
EH1_k127_7118722_2	1163617.SCD_n00760	3.944e-59	212.0	COG5266@1|root,COG5266@2|Bacteria,1RC3R@1224|Proteobacteria,2VQP6@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	ko:K10094	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.22	-	-	DUF4198
EH1_k127_7121147_2	557598.LHK_00309	2.889e-07	54.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,2KRBG@206351|Neisseriales	206351|Neisseriales	G	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH1_k127_7121147_1	69395.JQLZ01000001_gene3230	6.835e-43	165.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH1_k127_7121147_0	1123393.KB891316_gene1462	6.75e-141	454.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,1KREZ@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
EH1_k127_7121521_0	1348657.M622_18285	1.713e-161	523.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
EH1_k127_7140604_2	1123393.KB891316_gene1424	4.299e-46	173.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,2W1FP@28216|Betaproteobacteria,1KS5E@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_7140604_3	1163617.SCD_n00832	1.36e-34	147.0	COG0845@1|root,COG0845@2|Bacteria,1R9JJ@1224|Proteobacteria,2W4AP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH1_k127_7140604_0	1123392.AQWL01000002_gene2034	1.341e-161	513.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KRBV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
EH1_k127_7140604_4	1121035.AUCH01000006_gene684	2.637e-32	131.0	COG0840@1|root,COG0840@2|Bacteria,1PGTY@1224|Proteobacteria,2WB5T@28216|Betaproteobacteria,2KZDD@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
EH1_k127_7140604_1	1123392.AQWL01000006_gene721	3.336e-134	436.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cobalamin synthesis protein	yjiA_2	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
EH1_k127_7140604_5	292415.Tbd_0245	1.773e-05	54.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria	1224|Proteobacteria	V	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7166825_0	1458357.BG58_00430	4.048e-110	362.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,1K0VA@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH1_k127_7166825_2	640081.Dsui_1714	1.501e-30	124.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,2VWS3@28216|Betaproteobacteria,2KX88@206389|Rhodocyclales	206389|Rhodocyclales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
EH1_k127_7166825_1	640081.Dsui_1715	1.286e-68	243.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2VKGP@28216|Betaproteobacteria,2KVU6@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma factor PP2C-like phosphatases	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
EH1_k127_717623_1	1163617.SCD_n01994	1.286e-57	207.0	COG0517@1|root,COG0517@2|Bacteria,1RE9W@1224|Proteobacteria,2VSNZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH1_k127_717623_0	292415.Tbd_2134	8.177e-176	553.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,1KRB3@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
EH1_k127_717623_2	1123392.AQWL01000005_gene2866	6.08e-20	91.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,1KRW1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
EH1_k127_717623_3	1123008.KB905694_gene1778	8.108e-07	58.0	COG3439@1|root,COG3439@2|Bacteria,4PB0E@976|Bacteroidetes,2FY5F@200643|Bacteroidia,230MH@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH1_k127_7200895_1	582744.Msip34_1315	8.698e-70	261.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,2KMK5@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
EH1_k127_7200895_0	292415.Tbd_1228	4.249e-144	473.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KS5V@119069|Hydrogenophilales	119069|Hydrogenophilales	L	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
EH1_k127_7207958_0	1123393.KB891332_gene2785	3.974e-157	509.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KS5H@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
EH1_k127_7207958_1	243365.CV_0988	7.067e-77	260.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,2KPW1@206351|Neisseriales	206351|Neisseriales	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
EH1_k127_7226910_1	1485544.JQKP01000001_gene1098	9.172e-88	307.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2W994@28216|Betaproteobacteria,44WD7@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
EH1_k127_7226910_0	1123393.KB891328_gene593	2.056e-101	350.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VS5V@28216|Betaproteobacteria,1KSNQ@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7241253_0	1163617.SCD_n01805	6.635e-169	535.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
EH1_k127_7241253_1	1163617.SCD_n01806	8.64e-103	347.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
EH1_k127_7241253_2	1121035.AUCH01000019_gene2859	5.207e-10	63.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,2KWT1@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
EH1_k127_7243646_5	375286.mma_0454	1.253e-13	70.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VRSF@28216|Betaproteobacteria,475NC@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH1_k127_7243646_4	1123392.AQWL01000002_gene1747	2.344e-61	219.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2W3S1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
EH1_k127_7243646_2	1323663.AROI01000005_gene3074	3.147e-110	368.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM C4-dicarboxylate transporter malic acid transport protein	tehA	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
EH1_k127_7243646_3	296591.Bpro_4278	5.77e-84	286.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH1_k127_7243646_0	381666.H16_A1621	2.004e-262	841.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,1KBX2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
EH1_k127_7243646_1	1163617.SCD_n01585	9.387e-203	637.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,2VZ32@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH1_k127_7272242_0	1120999.JONM01000001_gene1226	2.588e-189	616.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQNU@206351|Neisseriales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg
EH1_k127_7272242_1	3988.XP_002539265.1	9.403e-43	166.0	2CY75@1|root,2S2HA@2759|Eukaryota	2759|Eukaryota	S	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH1_k127_728086_6	1163617.SCD_n00906	4.003e-32	135.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
EH1_k127_728086_0	1163617.SCD_n00905	1.286e-90	309.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH1_k127_728086_4	1123393.KB891316_gene1128	5.326e-44	164.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,1KS4V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH1_k127_728086_3	1123392.AQWL01000001_gene1588	5.748e-71	244.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
EH1_k127_728086_1	314345.SPV1_13262	7.797e-88	304.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
EH1_k127_728086_5	1123393.KB891328_gene550	7.04e-43	160.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,1KRV8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	S4
EH1_k127_728086_7	1123393.KB891316_gene1891	4.135e-22	103.0	2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,2WC53@28216|Betaproteobacteria,1KT3Z@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_728086_2	1123368.AUIS01000001_gene2021	2.59e-78	267.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,2ND1R@225057|Acidithiobacillales	225057|Acidithiobacillales	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
EH1_k127_7299818_0	1123393.KB891333_gene2583	1.688e-167	531.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria,1KSZQ@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH1_k127_7299818_5	1266925.JHVX01000004_gene1112	1.076e-22	103.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,373C3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
EH1_k127_7299818_3	94624.Bpet1751	6.045e-29	115.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,3T4QE@506|Alcaligenaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
EH1_k127_7299818_2	583345.Mmol_1146	3.966e-143	461.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,2KMA0@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
EH1_k127_7299818_1	1123393.KB891333_gene2579	4.365e-149	479.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KRA1@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
EH1_k127_7299818_4	983917.RGE_44850	1.469e-26	117.0	COG1807@1|root,COG1807@2|Bacteria,1RE4T@1224|Proteobacteria,2VQBA@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
EH1_k127_7306192_11	202952.BBLI01000008_gene828	2.441e-09	58.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7306192_12	360095.BARBAKC583_1300	2.654e-08	56.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7306192_3	1123393.KB891328_gene654	1.021e-98	333.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,1KSIP@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
EH1_k127_7306192_9	557598.LHK_00145	1.938e-44	167.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KR0M@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
EH1_k127_7306192_7	1485544.JQKP01000001_gene923	6.261e-56	201.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,44VR4@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH1_k127_7306192_0	292415.Tbd_2437	3.129e-228	716.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,1KSFE@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
EH1_k127_7306192_1	1123393.KB891316_gene1755	2.744e-184	597.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2W1AV@28216|Betaproteobacteria,1KS9Y@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
EH1_k127_7306192_10	380394.Lferr_0437	1.315e-12	79.0	COG1872@1|root,COG1872@2|Bacteria,1NGWG@1224|Proteobacteria,1SY5J@1236|Gammaproteobacteria,2NDAJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
EH1_k127_7306192_8	1123393.KB891316_gene1757	1.658e-45	180.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,1KRVR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
EH1_k127_7306192_6	1000565.METUNv1_02974	4.677e-78	273.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,2KUUS@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
EH1_k127_7306192_5	342113.DM82_2518	7.008e-85	287.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
EH1_k127_7306192_2	292415.Tbd_2419	2.404e-182	574.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,1KRIC@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH1_k127_7306192_4	1123393.KB891316_gene1761	6.99e-97	324.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,1KRF2@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type II/IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH1_k127_7313823_1	497321.C664_16455	6.277e-79	274.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUPC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,MCPsignal,PAS_3
EH1_k127_7313823_0	1123393.KB891327_gene292	1.883e-155	505.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,1KS25@119069|Hydrogenophilales	119069|Hydrogenophilales	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
EH1_k127_7313823_2	1123392.AQWL01000003_gene452	3.561e-63	218.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,1KSD8@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Polyphosphate kinase middle domain	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
EH1_k127_7322121_3	1280952.HJA_03801	1.114e-10	63.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
EH1_k127_7322121_1	1123393.KB891329_gene928	6.66e-54	193.0	2EDED@1|root,337AR@2|Bacteria,1PWPZ@1224|Proteobacteria,2WC88@28216|Betaproteobacteria,1KT8C@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7322121_4	713586.KB900536_gene2380	2.727e-10	63.0	2EJVT@1|root,33DKI@2|Bacteria,1NKVD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7322121_0	1210884.HG799462_gene8570	2.344e-64	226.0	COG0229@1|root,COG0229@2|Bacteria,2J37K@203682|Planctomycetes	203682|Planctomycetes	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
EH1_k127_7322121_2	94624.Bpet2108	6.091e-16	84.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria,3T297@506|Alcaligenaceae	28216|Betaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
EH1_k127_7346439_0	1123393.KB891316_gene1178	5.667e-231	721.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,1KSXK@119069|Hydrogenophilales	119069|Hydrogenophilales	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
EH1_k127_7346439_1	1163617.SCD_n00898	3.342e-21	93.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
EH1_k127_7347304_0	864051.BurJ1DRAFT_1480	3.483e-169	541.0	COG0502@1|root,COG0502@2|Bacteria,1QWVD@1224|Proteobacteria,2WH18@28216|Betaproteobacteria,1KMSG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH1_k127_7361596_0	1485544.JQKP01000002_gene1464	1.075e-162	535.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS,PAS_4,dCache_3
EH1_k127_7362070_0	420662.Mpe_B0283	8.524e-17	94.0	COG1389@1|root,COG1389@2|Bacteria,1P37I@1224|Proteobacteria	1224|Proteobacteria	L	DNA topoisomerase II activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7380849_0	1121423.JONT01000003_gene978	2.907e-108	358.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
EH1_k127_7380849_4	2325.TKV_c19540	1.142e-16	83.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia,42HEV@68295|Thermoanaerobacterales	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH1_k127_7380849_2	521011.Mpal_0263	3.17e-36	143.0	COG0730@1|root,arCOG02050@2157|Archaea,2XXQV@28890|Euryarchaeota	28890|Euryarchaeota	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH1_k127_7380849_1	635013.TherJR_1183	5.305e-50	184.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,261R4@186807|Peptococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
EH1_k127_7380849_3	255470.cbdbA588	5.867e-27	110.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi,34D5N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
EH1_k127_738849_0	649638.Trad_0273	1.867e-136	439.0	COG0514@1|root,COG0514@2|Bacteria,1WJC6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM ATP-dependent DNA helicase, RecQ	recQ1	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
EH1_k127_738849_1	1144325.PMI22_00273	1.093e-17	85.0	2E43B@1|root,32YZP@2|Bacteria,1NG2F@1224|Proteobacteria,1SFP3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7392599_0	29581.BW37_05092	1.633e-146	482.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,4730W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
EH1_k127_7392600_0	292415.Tbd_1907	9.893e-85	282.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KRAP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH1_k127_7392600_1	1163617.SCD_n00378	9.921e-52	191.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH1_k127_7392600_2	713587.THITH_07520	4.419e-19	91.0	COG3062@1|root,COG3062@2|Bacteria,1PUNN@1224|Proteobacteria,1TKDR@1236|Gammaproteobacteria,1X21U@135613|Chromatiales	135613|Chromatiales	P	NapD protein	-	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
EH1_k127_7396639_1	292415.Tbd_0217	7.51e-56	204.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,1KSVV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA
EH1_k127_7396639_0	1123393.KB891331_gene2852	4.857e-108	354.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,1KRE2@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH1_k127_7400569_0	1123392.AQWL01000003_gene493	1.226e-134	434.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,1KRIY@119069|Hydrogenophilales	119069|Hydrogenophilales	E	AIR synthase related protein, N-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
EH1_k127_7400614_0	1123393.KB891327_gene383	3.342e-124	399.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,1KRDN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
EH1_k127_7400614_1	1163617.SCD_n00947	5.019e-89	296.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
EH1_k127_7400614_2	62928.azo1405	1.057e-71	254.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,2KW5Z@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
EH1_k127_740094_1	525904.Tter_1528	4.547e-94	314.0	COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH1_k127_740094_0	525904.Tter_1527	1.43e-107	359.0	COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,Transket_pyr,Transketolase_C
EH1_k127_7403643_2	1244869.H261_04118	4.92e-63	223.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2TTSC@28211|Alphaproteobacteria,2JQZJ@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
EH1_k127_7403643_0	1163617.SCD_n00063	8.411e-168	557.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH1_k127_7403643_1	1163617.SCD_n00064	5.872e-102	344.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH1_k127_7405011_0	652103.Rpdx1_2285	1.409e-50	182.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,3K3W8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
EH1_k127_7405011_1	1158292.JPOE01000002_gene1673	1.122e-47	174.0	2AE70@1|root,32VN7@2|Bacteria,1N3TT@1224|Proteobacteria,2VVAV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7405011_2	1123393.KB891316_gene1967	1.906e-44	165.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,2VUQQ@28216|Betaproteobacteria,1KT2W@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
EH1_k127_7405011_3	1366050.N234_35140	2.746e-27	115.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,1K3UW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Chromate resistance	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH1_k127_7405676_0	1123392.AQWL01000002_gene1997	8.354e-102	335.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,1KSRP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function, DUF480	-	-	-	-	-	-	-	-	-	-	-	-	DUF480
EH1_k127_7405676_1	768671.ThimaDRAFT_1370	9.176e-95	322.0	COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH1_k127_7408547_0	1123368.AUIS01000005_gene487	3.835e-218	683.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RYC8@1236|Gammaproteobacteria,2NC3Q@225057|Acidithiobacillales	225057|Acidithiobacillales	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
EH1_k127_7408547_1	396588.Tgr7_2031	1.565e-33	133.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1WVZF@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
EH1_k127_7418553_1	582744.Msip34_2500	7.957e-73	249.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KMCZ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH1_k127_7418553_0	1123393.KB891330_gene782	1.879e-174	553.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1KSC8@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
EH1_k127_7456985_1	1049564.TevJSym_bk00240	4.334e-76	265.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1JAVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
EH1_k127_7456985_0	748247.AZKH_2231	8.787e-318	980.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,2KU7H@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
EH1_k127_7492283_0	1123392.AQWL01000009_gene1121	3.935e-257	806.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria,1KSRU@119069|Hydrogenophilales	119069|Hydrogenophilales	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
EH1_k127_7492283_2	511.JT27_04385	2.958e-21	106.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,3T2GI@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG3245 Cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_7492283_1	292415.Tbd_0869	4.776e-148	471.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
EH1_k127_7492283_3	1123368.AUIS01000001_gene1863	8.006e-05	51.0	2EIBB@1|root,33C2R@2|Bacteria,1PS8K@1224|Proteobacteria,1ST8B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7492885_1	497321.C664_01825	1.114e-169	535.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,2KUW9@206389|Rhodocyclales	206389|Rhodocyclales	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
EH1_k127_7492885_0	243365.CV_2758	1.173e-234	742.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KPUY@206351|Neisseriales	206351|Neisseriales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
EH1_k127_7513444_0	1163617.SCD_n01875	0.0	1227.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
EH1_k127_7532366_0	580332.Slit_2936	9.225e-241	787.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,44W8H@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH1_k127_7532366_1	1121035.AUCH01000006_gene765	6.378e-132	425.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
EH1_k127_7532888_1	1123393.KB891330_gene854	2.266e-102	337.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2VURW@28216|Betaproteobacteria,1KSAA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Homoserine O-succinyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTS
EH1_k127_7532888_0	1123393.KB891330_gene855	5.59e-155	493.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,2WBNB@28216|Betaproteobacteria,1KS8Q@119069|Hydrogenophilales	119069|Hydrogenophilales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7537820_0	1163617.SCD_n00508	5.885e-223	704.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
EH1_k127_757958_0	1454004.AW11_02181	6.58e-77	263.0	COG2204@1|root,COG2204@2|Bacteria,1NH9G@1224|Proteobacteria,2VK96@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
EH1_k127_757958_1	1123261.AXDW01000010_gene339	1.844e-40	162.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
EH1_k127_7584219_0	857087.Metme_3258	4.137e-274	859.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
EH1_k127_7586854_2	76114.ebB140	1.488e-26	109.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,2KXDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
EH1_k127_7586854_0	349521.HCH_00267	4.461e-29	127.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria,1XRNY@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7586854_3	1449351.RISW2_00400	0.000251	53.0	29NNR@1|root,309KP@2|Bacteria,1R91H@1224|Proteobacteria,2TUSZ@28211|Alphaproteobacteria,4KKTA@93682|Roseivivax	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7586854_1	1163617.SCD_n00088	5.342e-28	116.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
EH1_k127_7590757_2	768671.ThimaDRAFT_4078	8.635e-32	126.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S4KA@1236|Gammaproteobacteria,1WY97@135613|Chromatiales	135613|Chromatiales	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_7590757_1	768671.ThimaDRAFT_4079	3.573e-70	245.0	COG2863@1|root,COG2863@2|Bacteria,1RCAT@1224|Proteobacteria,1T09H@1236|Gammaproteobacteria,1X2M4@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7590757_3	765911.Thivi_1726	7.85e-28	121.0	COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria,1S1Q4@1236|Gammaproteobacteria,1X0RI@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_7590757_0	1121033.AUCF01000010_gene4430	1.307e-115	386.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TT55@28211|Alphaproteobacteria,2JQHI@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfide dehydrogenase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
EH1_k127_7590842_6	1163617.SCD_n03031	1.398e-68	237.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
EH1_k127_7590842_7	1123393.KB891332_gene2792	5.196e-65	232.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,1KRP8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	rRNA small subunit methyltransferase G	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
EH1_k127_7590842_5	1266925.JHVX01000008_gene372	3.171e-102	339.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH1_k127_7590842_4	159087.Daro_4106	7.747e-108	356.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
EH1_k127_7590842_12	1123392.AQWL01000013_gene2374	4.591e-07	56.0	2AFZN@1|root,3163M@2|Bacteria,1PWSS@1224|Proteobacteria,2WCBE@28216|Betaproteobacteria,1KTD3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATP synthase I chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
EH1_k127_7590842_3	292415.Tbd_2803	4.663e-127	412.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
EH1_k127_7590842_11	1123392.AQWL01000013_gene2376	2.09e-34	132.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
EH1_k127_7590842_8	1123392.AQWL01000013_gene2377	1.484e-62	218.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,1KS17@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
EH1_k127_7590842_10	323848.Nmul_A0307	4.334e-46	171.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,3737S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
EH1_k127_7590842_0	323848.Nmul_A0308	2.385e-282	872.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,371UU@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
EH1_k127_7590842_2	292415.Tbd_2798	4.666e-132	429.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,1KSC4@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
EH1_k127_7590842_1	292415.Tbd_2797	2.905e-262	811.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1KS24@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
EH1_k127_7590842_9	1123393.KB891332_gene2803	3.383e-55	196.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KRPP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
EH1_k127_7590842_13	1122194.AUHU01000008_gene3356	2.99e-05	48.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,465MW@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_4420,iYL1228.KPN_04135	Hexapep,Hexapep_2,NTP_transf_3
EH1_k127_7596856_1	497321.C664_03570	1.841e-86	293.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KUEU@206389|Rhodocyclales	206389|Rhodocyclales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
EH1_k127_7596856_0	1123392.AQWL01000011_gene2217	3.451e-181	577.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KREY@119069|Hydrogenophilales	119069|Hydrogenophilales	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH1_k127_7596856_3	396588.Tgr7_0643	2.251e-56	199.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
EH1_k127_7596856_2	1123393.KB891316_gene2125	8.107e-64	228.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,1KSVX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
EH1_k127_7609661_11	859657.RPSI07_2804	4.781e-35	143.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,1K2NH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
EH1_k127_7609661_0	1163617.SCD_n00848	1.233e-188	593.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
EH1_k127_7609661_8	1123393.KB891316_gene1506	3.288e-52	189.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,1KS4X@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
EH1_k127_7609661_9	472759.Nhal_2449	1.683e-43	164.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1WY89@135613|Chromatiales	135613|Chromatiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
EH1_k127_7609661_3	580332.Slit_0657	1.209e-116	385.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,44VFP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
EH1_k127_7609661_10	1265502.KB905943_gene2725	1.468e-41	158.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,4ACUC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
EH1_k127_7609661_7	748247.AZKH_0440	1.241e-62	219.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,2KW8Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
EH1_k127_7609661_1	292415.Tbd_2190	3.72e-173	551.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,1KS3N@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
EH1_k127_7609661_5	292415.Tbd_2189	8.172e-78	265.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1KSH3@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
EH1_k127_7609661_4	1123393.KB891316_gene1481	2.238e-83	301.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,1KSWC@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH1_k127_7609661_2	292415.Tbd_2168	6.088e-155	502.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KS4K@119069|Hydrogenophilales	119069|Hydrogenophilales	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
EH1_k127_7609661_6	1123392.AQWL01000005_gene2903	5.796e-64	222.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,1KSP2@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
EH1_k127_7615551_0	857087.Metme_0874	1.429e-160	530.0	COG3291@1|root,COG3291@2|Bacteria,1RGWM@1224|Proteobacteria,1THXR@1236|Gammaproteobacteria,1XFZT@135618|Methylococcales	135618|Methylococcales	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
EH1_k127_7615551_1	1163617.SCD_n01735	2.872e-111	369.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
EH1_k127_7615551_2	1123367.C666_01455	8.89e-19	87.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria,2KUB4@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
EH1_k127_7636573_0	292415.Tbd_0879	4.702e-236	738.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,1KSFP@119069|Hydrogenophilales	119069|Hydrogenophilales	HI	Transketolase, pyrimidine binding domain	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
EH1_k127_7636573_1	1123392.AQWL01000007_gene929	3.591e-150	479.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,1KSEU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Type I GTP cyclohydrolase folE2	-	-	-	-	-	-	-	-	-	-	-	-	GCHY-1
EH1_k127_7636573_2	1485544.JQKP01000015_gene2068	2.916e-107	353.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,44V94@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
EH1_k127_7647601_2	1112274.KI911560_gene2172	1.067e-29	119.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KMA8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH1_k127_7647601_1	1163617.SCD_n00983	1.139e-57	214.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
EH1_k127_7647601_0	1123393.KB891331_gene2919	2.736e-284	901.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
EH1_k127_7653505_0	1123392.AQWL01000007_gene878	1.08e-276	863.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH1_k127_7663847_1	1266908.AQPB01000043_gene1424	1.102e-47	183.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,1RYHZ@1236|Gammaproteobacteria,1X0DU@135613|Chromatiales	135613|Chromatiales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD
EH1_k127_7663847_0	1198452.Jab_2c32490	4.69e-50	184.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,473CS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
EH1_k127_7687325_1	1211777.BN77_3239	7.055e-12	71.0	COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,2U12R@28211|Alphaproteobacteria,4BAD3@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
EH1_k127_7687325_0	1163617.SCD_n00906	1.098e-193	613.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
EH1_k127_7688366_0	485913.Krac_3083	5.858e-158	525.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
EH1_k127_7690012_5	76114.ebA3391	1.264e-49	187.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
EH1_k127_7690012_7	1163617.SCD_n00556	5.552e-40	151.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
EH1_k127_7690012_1	748247.AZKH_4325	3.598e-153	497.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KV3Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN1	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
EH1_k127_7690012_3	1288494.EBAPG3_7420	1.301e-106	355.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,372DG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
EH1_k127_7690012_6	1123393.KB891328_gene578	1.658e-45	171.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,1KSET@119069|Hydrogenophilales	119069|Hydrogenophilales	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
EH1_k127_7690012_8	686340.Metal_0242	8.561e-14	79.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,1S3S8@1236|Gammaproteobacteria,1XF9D@135618|Methylococcales	135618|Methylococcales	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
EH1_k127_7690012_4	292415.Tbd_0537	3.482e-64	225.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,1KSY1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
EH1_k127_7690012_2	1123393.KB891328_gene581	2.125e-138	447.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1KSCX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
EH1_k127_7690012_0	1163617.SCD_n00563	1.003e-180	582.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
EH1_k127_7725838_2	1211813.CAPH01000001_gene1170	8.844e-16	82.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
EH1_k127_7725838_0	32057.KB217478_gene1060	4.031e-120	402.0	COG3385@1|root,COG3385@2|Bacteria,1G2W3@1117|Cyanobacteria	2|Bacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
EH1_k127_7725838_1	196367.JNFG01000214_gene1304	6.742e-48	174.0	COG3464@1|root,COG3464@2|Bacteria,1R8HI@1224|Proteobacteria,2VT67@28216|Betaproteobacteria,1KHTC@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,TrfA
EH1_k127_7764785_1	640081.Dsui_3038	1.083e-124	403.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
EH1_k127_7764785_0	1163617.SCD_n00950	0.0	1010.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
EH1_k127_7764785_2	1502770.JQMG01000001_gene1613	3.773e-45	165.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,2KMXI@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
EH1_k127_7780134_3	1123393.KB891329_gene972	6.559e-88	302.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,1KRD6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH1_k127_7780134_0	1123393.KB891329_gene973	1.287e-105	347.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,1KRGQ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
EH1_k127_7780134_2	1123393.KB891329_gene974	7.133e-93	314.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,1KSGP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
EH1_k127_7780134_1	497321.C664_04727	1.291e-94	317.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KUM6@206389|Rhodocyclales	206389|Rhodocyclales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH1_k127_7810208_1	765911.Thivi_4046	2.193e-77	262.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1X2FQ@135613|Chromatiales	135613|Chromatiales	G	isomerase	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
EH1_k127_7810208_0	765911.Thivi_4047	8.283e-80	281.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RQPI@1236|Gammaproteobacteria,1WW2A@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
EH1_k127_7810208_2	335283.Neut_0160	1.068e-40	158.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2W9Y0@28216|Betaproteobacteria,374IN@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
EH1_k127_7811481_0	1123393.KB891331_gene2919	0.0	1019.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
EH1_k127_7817486_4	1163617.SCD_n02466	2.582e-88	295.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
EH1_k127_7817486_0	1123393.KB891316_gene1696	1.489e-244	768.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KRC1@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
EH1_k127_7817486_2	1163617.SCD_n02464	2.963e-145	471.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	CBS domain containing protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
EH1_k127_7817486_6	748247.AZKH_1172	3.23e-32	130.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
EH1_k127_7817486_1	1163617.SCD_n01050	8.475e-190	608.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
EH1_k127_7817486_3	1485544.JQKP01000013_gene1837	3.433e-122	396.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
EH1_k127_7817486_5	1485544.JQKP01000007_gene1971	9.582e-48	179.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,44VZS@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
EH1_k127_7843026_2	1123392.AQWL01000003_gene288	2.829e-32	128.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,1KRE0@119069|Hydrogenophilales	119069|Hydrogenophilales	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
EH1_k127_7843026_1	323848.Nmul_A2590	3.165e-62	216.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,37356@32003|Nitrosomonadales	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
EH1_k127_7843026_0	1123368.AUIS01000016_gene2552	2.568e-135	442.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2NCMQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	PFAM type II secretion system	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
EH1_k127_7848231_1	1123393.KB891316_gene1415	2.472e-185	584.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KS7N@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
EH1_k127_7848231_2	1123392.AQWL01000001_gene1372	1.161e-114	371.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1KRBR@119069|Hydrogenophilales	119069|Hydrogenophilales	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
EH1_k127_7848231_0	1123487.KB892844_gene837	0.0	1036.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,2KV3G@206389|Rhodocyclales	206389|Rhodocyclales	E	COG1982 Arginine lysine ornithine decarboxylases	adiA	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
EH1_k127_7849265_0	1123367.C666_02565	8.535e-116	380.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KUHC@206389|Rhodocyclales	206389|Rhodocyclales	I	Squalene synthase HpnD	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
EH1_k127_7849265_1	1163617.SCD_n01778	4.621e-108	364.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
EH1_k127_7849265_2	1266925.JHVX01000010_gene1332	9.803e-75	276.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2VMWZ@28216|Betaproteobacteria,372M9@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH1_k127_7849265_3	748247.AZKH_2443	4.198e-52	187.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,2KZ5E@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the DsbB family	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
EH1_k127_784963_5	580332.Slit_1987	1.006e-13	72.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,44V6Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM glycine cleavage T protein (aminomethyl transferase)	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
EH1_k127_784963_6	279714.FuraDRAFT_2987	1.096e-07	60.0	2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2WB54@28216|Betaproteobacteria,2KTH2@206351|Neisseriales	206351|Neisseriales	S	Domain of unknown function (DUF4936)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4936
EH1_k127_784963_3	580332.Slit_0737	4.004e-71	244.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,44WBD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
EH1_k127_784963_1	1304883.KI912532_gene1408	3.29e-104	343.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KUF5@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
EH1_k127_784963_4	1123393.KB891316_gene1722	4.04e-35	138.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,1KT0G@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_784963_0	1163617.SCD_n02700	3.901e-202	639.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
EH1_k127_784963_2	1163617.SCD_n02699	2.353e-77	268.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	peptidase	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH1_k127_7857047_2	472759.Nhal_0313	4.422e-61	216.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1WX07@135613|Chromatiales	135613|Chromatiales	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
EH1_k127_7857047_0	330214.NIDE0211	3.27e-92	319.0	COG3496@1|root,COG3496@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1365)	-	-	2.1.1.79	ko:K00574,ko:K09701	-	-	-	-	ko00000,ko01000	-	-	-	DUF1365
EH1_k127_7857047_1	887062.HGR_05449	5.408e-69	239.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
EH1_k127_7884612_3	123899.JPQP01000002_gene828	2.548e-12	66.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,3T1IP@506|Alcaligenaceae	28216|Betaproteobacteria	H	Molybdenum cofactor biosynthesis protein MogA	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
EH1_k127_7884612_0	1000565.METUNv1_03823	8.243e-134	434.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,2KUZN@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH1_k127_7884612_1	261292.Nit79A3_2084	3.837e-47	180.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,372XF@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
EH1_k127_7884612_2	1121035.AUCH01000002_gene1588	1.991e-43	169.0	COG3221@1|root,COG3221@2|Bacteria,1R49P@1224|Proteobacteria,2VN1C@28216|Betaproteobacteria,2KVS5@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH1_k127_7902182_0	1123392.AQWL01000005_gene3212	1.311e-153	490.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,2VK6N@28216|Betaproteobacteria,1KSMP@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Dihydroorotate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DHO_dh
EH1_k127_790468_0	1485544.JQKP01000002_gene1406	1.083e-218	700.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
EH1_k127_790468_1	1304883.KI912532_gene1783	2.131e-200	634.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,2KUYG@206389|Rhodocyclales	206389|Rhodocyclales	C	Respiratory-chain NADH dehydrogenase	hoxF	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
EH1_k127_7907135_2	305700.B447_01996	1.826e-33	130.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,2KV1K@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
EH1_k127_7907135_3	748247.AZKH_0313	2.194e-09	60.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY2T@28216|Betaproteobacteria,2KXK6@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
EH1_k127_7907135_1	1288494.EBAPG3_12780	5.303e-64	223.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
EH1_k127_7907135_0	228410.NE0768	4.506e-84	282.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3725U@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
EH1_k127_7907850_2	675812.VHA_003135	1.447e-27	118.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XSQ8@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
EH1_k127_7907850_0	1123393.KB891316_gene1180	4.241e-73	259.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KSZ7@119069|Hydrogenophilales	119069|Hydrogenophilales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH1_k127_7907850_1	1163617.SCD_n00896	1.239e-57	207.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH1_k127_7911841_3	1335757.SPICUR_01905	1.575e-29	120.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,1SDJI@1236|Gammaproteobacteria,1WZBJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
EH1_k127_7911841_2	62928.azo2126	1.652e-82	277.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,2KWB4@206389|Rhodocyclales	206389|Rhodocyclales	S	YaeQ family	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
EH1_k127_7911841_4	1163617.SCD_n01361	3.312e-23	104.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,2VVQY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RNA-binding	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
EH1_k127_7911841_0	159087.Daro_1444	1.581e-273	850.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,2KXHK@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH1_k127_7911841_1	762966.HMPREF9439_02603	2.951e-249	778.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,4PQH6@995019|Sutterellaceae	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
EH1_k127_7935777_0	292415.Tbd_1717	1.634e-119	389.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,1KRK8@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH1_k127_7935777_3	1123392.AQWL01000008_gene1204	6.701e-27	119.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,2W4FH@28216|Betaproteobacteria,1KT96@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7935777_1	1485544.JQKP01000014_gene1900	9.254e-110	359.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
EH1_k127_7935777_2	1286106.MPL1_09405	4.427e-40	153.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,460UI@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH1_k127_7951813_0	266264.Rmet_1541	2.285e-226	714.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,2VK38@28216|Betaproteobacteria,1KBJJ@119060|Burkholderiaceae	28216|Betaproteobacteria	IJ	Formyl transferase	hoxX	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
EH1_k127_796559_0	1123393.KB891319_gene715	0.0	1806.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,1KS99@119069|Hydrogenophilales	119069|Hydrogenophilales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
EH1_k127_796559_1	267608.RSc3033	1.79e-23	99.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,1K0RX@119060|Burkholderiaceae	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
EH1_k127_7967324_1	1005048.CFU_2491	1.004e-37	145.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,472GS@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
EH1_k127_7967324_0	1123368.AUIS01000017_gene2573	5.801e-113	377.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,2NC30@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
EH1_k127_7972207_1	94624.Bpet3126	3.541e-59	207.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,3T32Z@506|Alcaligenaceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
EH1_k127_7972207_2	323259.Mhun_1415	1.533e-20	106.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,arCOG02352@1|root,arCOG02352@2157|Archaea,arCOG02356@2157|Archaea,arCOG02383@2157|Archaea,arCOG06192@2157|Archaea	2157|Archaea	T	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
EH1_k127_7972207_0	1123393.KB891326_gene84	7.93e-61	228.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KREN@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,dCache_1
EH1_k127_7986835_2	1122614.JHZF01000013_gene3463	7.194e-122	410.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH1_k127_7986835_1	1454004.AW11_00852	1.662e-128	417.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
EH1_k127_7986835_3	522306.CAP2UW1_2179	5.405e-26	112.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,2VVX7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
EH1_k127_7986835_0	1458427.BAWN01000020_gene1218	0.0	1116.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9Z9@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH1_k127_7986835_4	1348657.M622_06210	1.051e-17	87.0	2CDHM@1|root,344GF@2|Bacteria,1NZYE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_7989700_0	1207076.ALAT01000011_gene1557	1.143e-308	955.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1Z0JK@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH1_k127_7989700_1	292415.Tbd_2447	3.085e-33	131.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KRX2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH1_k127_7993488_0	1163617.SCD_n01864	5.267e-151	479.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
EH1_k127_8048032_0	1123393.KB891326_gene144	5.254e-287	884.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
EH1_k127_8048032_1	1123393.KB891326_gene145	5.473e-278	857.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
EH1_k127_8048032_2	1123393.KB891326_gene146	1.012e-103	342.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,2W26X@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
EH1_k127_8048032_3	1123393.KB891333_gene2567	2.773e-64	225.0	COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,2VUGP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
EH1_k127_8048032_4	349124.Hhal_1383	0.0003314	43.0	COG2518@1|root,COG2518@2|Bacteria,1QWH0@1224|Proteobacteria,1STVM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
EH1_k127_8049981_3	1215092.PA6_009_01300	9.445e-08	53.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,1S7AB@1236|Gammaproteobacteria,1YJFK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_8049981_0	292415.Tbd_2526	3.196e-122	399.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KRE1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Diaminopimelate epimerase	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
EH1_k127_8049981_1	1163617.SCD_n00312	4.471e-54	207.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
EH1_k127_8049981_2	159087.Daro_0194	1.756e-22	111.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,2KUG1@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH1_k127_8060463_0	85643.Tmz1t_3203	0.0	1014.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
EH1_k127_8060463_1	1163617.SCD_n01467	7.381e-29	120.0	COG0745@1|root,COG0745@2|Bacteria,1RETP@1224|Proteobacteria,2WGYY@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH1_k127_8062633_2	159087.Daro_0487	8.768e-29	118.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,2KW35@206389|Rhodocyclales	206389|Rhodocyclales	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
EH1_k127_8062633_0	76114.ebA6387	8.103e-109	364.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH1_k127_8062633_1	1163617.SCD_n01211	2.13e-51	185.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
EH1_k127_8067110_0	1123393.KB891330_gene842	4.168e-146	467.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KSIC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
EH1_k127_8067110_2	1304883.KI912532_gene696	1.452e-38	145.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KWWQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
EH1_k127_8067110_1	1163617.SCD_n00097	6.862e-52	184.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
EH1_k127_8092297_3	1163617.SCD_n00594	3.547e-47	170.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
EH1_k127_8092297_4	1163617.SCD_n00593	1.153e-42	160.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
EH1_k127_8092297_1	1163617.SCD_n00592	1.081e-62	227.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
EH1_k127_8092297_0	266265.Bxe_A0404	1.633e-132	429.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1K0MT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH1_k127_8092297_2	1387312.BAUS01000004_gene1825	2.788e-59	206.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KKGM@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH1_k127_8128966_0	1163617.SCD_n01915	0.0	1347.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
EH1_k127_8128966_5	580332.Slit_1972	2.099e-15	89.0	2EQBS@1|root,30WRI@2|Bacteria,1PWXX@1224|Proteobacteria,2WCFU@28216|Betaproteobacteria,44W00@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
EH1_k127_8128966_4	640081.Dsui_3432	6.251e-86	301.0	COG1538@1|root,COG1538@2|Bacteria,1R9PU@1224|Proteobacteria,2VPEH@28216|Betaproteobacteria,2KW3Y@206389|Rhodocyclales	206389|Rhodocyclales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH1_k127_8128966_2	1123393.KB891316_gene1857	1.787e-99	337.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,1KSK7@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
EH1_k127_8128966_3	292415.Tbd_2464	5.274e-96	332.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KSM0@119069|Hydrogenophilales	119069|Hydrogenophilales	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH1_k127_8128966_1	1123393.KB891316_gene1827	3.987e-153	490.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KS03@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
EH1_k127_8162001_0	472759.Nhal_1290	4.889e-144	478.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH1_k127_8171291_2	292415.Tbd_0827	1.995e-97	322.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria,1KSG7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH1_k127_8171291_1	395494.Galf_0008	3.024e-188	595.0	COG2301@1|root,COG2301@2|Bacteria,1PCZW@1224|Proteobacteria,2W07M@28216|Betaproteobacteria	28216|Betaproteobacteria	G	HpcH HpaI aldolase	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
EH1_k127_8171291_0	395494.Galf_0009	6.538e-255	796.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
EH1_k127_8188838_0	1163617.SCD_n00511	4.243e-292	915.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH1_k127_8188838_3	1008459.TASI_0975	1.33e-21	100.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,3T4SK@506|Alcaligenaceae	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
EH1_k127_8188838_2	1123393.KB891316_gene1130	2.633e-72	249.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,1KSJC@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
EH1_k127_8188838_1	28072.Nos7524_1685	7.019e-108	390.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GK47@1117|Cyanobacteria,1HT8F@1161|Nostocales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
EH1_k127_8195217_2	589865.DaAHT2_2510	2.309e-18	100.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42MRE@68525|delta/epsilon subdivisions,2WIP0@28221|Deltaproteobacteria,2MIDJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH1_k127_8195217_1	1121403.AUCV01000016_gene4409	6.983e-120	406.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MHR5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
EH1_k127_8195217_0	1123392.AQWL01000006_gene636	1.856e-242	761.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH1_k127_8202401_2	546266.NEIMUCOT_06352	7.394e-10	63.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	yqiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
EH1_k127_8202401_0	1158165.KB898871_gene2220	6.073e-83	287.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH1_k127_8202401_1	395494.Galf_0288	1.888e-60	217.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,44V8D@713636|Nitrosomonadales	28216|Betaproteobacteria	HL	Thiamine monophosphate synthase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
EH1_k127_8225389_0	439235.Dalk_1820	2.714e-205	654.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2MISZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C554,Cytochrome_cB
EH1_k127_8225389_2	1265505.ATUG01000001_gene3057	2.055e-27	119.0	COG2010@1|root,COG2010@2|Bacteria,1N5GJ@1224|Proteobacteria,42WJ1@68525|delta/epsilon subdivisions,2WS5V@28221|Deltaproteobacteria,2MP5X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH1_k127_8225389_1	1307759.JOMJ01000003_gene1421	5.282e-101	334.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2M8UY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH1_k127_8230974_2	1266925.JHVX01000009_gene93	3.206e-34	141.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,37270@32003|Nitrosomonadales	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH1_k127_8230974_1	640081.Dsui_3085	1.887e-87	301.0	COG0457@1|root,COG4319@1|root,COG0457@2|Bacteria,COG4319@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,2KUGG@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17
EH1_k127_8230974_0	1163617.SCD_n00898	1.44e-308	951.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
EH1_k127_8237545_2	1163617.SCD_n00762	1.01e-144	465.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VHPC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	formate dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
EH1_k127_8237545_0	1163617.SCD_n00761	6.176e-184	583.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH1_k127_8237545_3	1148.1001258	3.559e-07	58.0	COG3895@1|root,COG3895@2|Bacteria,1GFWT@1117|Cyanobacteria,1H6MX@1142|Synechocystis	1117|Cyanobacteria	S	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	MliC
EH1_k127_8237545_1	1304883.KI912532_gene771	2.437e-183	582.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,2KUPM@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function DUF21	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
EH1_k127_8245278_0	159087.Daro_1734	7.431e-163	520.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,2KUWJ@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH1_k127_8245278_1	1123392.AQWL01000004_gene2670	2.681e-136	438.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1KREJ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH1_k127_8252780_0	99598.Cal7507_3739	2.586e-130	431.0	COG3292@1|root,COG3292@2|Bacteria,1G8JD@1117|Cyanobacteria	1117|Cyanobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
EH1_k127_8252780_1	99598.Cal7507_3740	4.131e-97	333.0	COG4447@1|root,COG4447@2|Bacteria,1G5IX@1117|Cyanobacteria	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Peptidase_S74
EH1_k127_8252780_3	1485544.JQKP01000011_gene744	6.727e-06	48.0	COG3926@1|root,COG3926@2|Bacteria,1PVUY@1224|Proteobacteria,2WBHU@28216|Betaproteobacteria,44WKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
EH1_k127_8252780_2	1485544.JQKP01000011_gene745	7.225e-29	120.0	2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2VY99@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Holin of 3TMs, for gene-transfer release	-	-	-	-	-	-	-	-	-	-	-	-	GTA_holin_3TM
EH1_k127_8267415_1	582744.Msip34_0044	7.394e-111	364.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KM1J@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH1_k127_8267415_0	1123393.KB891316_gene1260	2.127e-157	501.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KSYR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH1_k127_8267415_2	273526.SMDB11_0776	1.551e-86	293.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,401W0@613|Serratia	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
EH1_k127_8279287_5	522306.CAP2UW1_2458	7.322e-14	73.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,1KQ2V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
EH1_k127_8279287_0	1123393.KB891331_gene2844	3.31e-158	506.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,1KRVI@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
EH1_k127_8279287_2	62928.azo3822	5.163e-58	205.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,2KWU9@206389|Rhodocyclales	206389|Rhodocyclales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
EH1_k127_8279287_3	1349767.GJA_422	2.732e-47	184.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,473MP@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
EH1_k127_8279287_1	1123261.AXDW01000001_gene1332	5.692e-72	254.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X97T@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
EH1_k127_8279287_4	335283.Neut_1263	5.286e-28	113.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,372FQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH1_k127_8291237_2	644801.Psest_0262	0.0003772	49.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1T25X@1236|Gammaproteobacteria,1YZWP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,Response_reg
EH1_k127_8291237_0	1163617.SCD_n01281	1.484e-294	908.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
EH1_k127_8291237_1	1163617.SCD_n01280	5.904e-53	187.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
EH1_k127_8296305_2	1123367.C666_11665	9.441e-46	173.0	COG2863@1|root,COG2863@2|Bacteria,1RC61@1224|Proteobacteria,2VQSA@28216|Betaproteobacteria,2KW6I@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH1_k127_8296305_1	583345.Mmol_2201	3.814e-85	295.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KMAQ@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the peptidase S11 family	-	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
EH1_k127_8296305_0	748247.AZKH_0271	1.326e-111	366.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,2KVKQ@206389|Rhodocyclales	206389|Rhodocyclales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
EH1_k127_8296305_3	1123354.AUDR01000012_gene1838	2.195e-11	65.0	COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,2VTGB@28216|Betaproteobacteria	28216|Betaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
EH1_k127_8307116_1	580332.Slit_1885	1.479e-16	88.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,44VM7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
EH1_k127_8307116_0	305700.B447_03918	1.571e-318	979.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KVHT@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
EH1_k127_8315110_2	987059.RBXJA2T_18343	3.412e-58	205.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KJ2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
EH1_k127_8315110_0	1123393.KB891316_gene1434	1.085e-142	456.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,1KS76@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
EH1_k127_8315110_3	1123392.AQWL01000001_gene1349	1.051e-21	96.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
EH1_k127_8315110_1	582744.Msip34_0067	7.092e-111	362.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,2KKIA@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
EH1_k127_8321613_0	1123368.AUIS01000033_gene1378	1.748e-99	330.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Pseudouridine synthase	truC	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
EH1_k127_8321613_5	1088868.CIN_08060	0.0004328	50.0	28Y9S@1|root,2ZK4K@2|Bacteria,1P5V2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_8321613_3	159087.Daro_1560	3.024e-19	93.0	2EI92@1|root,33C0E@2|Bacteria,1NHN6@1224|Proteobacteria,2VYC9@28216|Betaproteobacteria,2KXI8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_8321613_1	1123393.KB891333_gene2613	6.676e-65	226.0	COG0537@1|root,COG0537@2|Bacteria,1N3EA@1224|Proteobacteria,2VSGA@28216|Betaproteobacteria,1KT4C@119069|Hydrogenophilales	119069|Hydrogenophilales	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	-	-	-	-	-	-	-	-	-	HIT
EH1_k127_8321613_2	1215092.PA6_046_00180	3.242e-34	136.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1YKR1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
EH1_k127_8321702_4	1288494.EBAPG3_4030	2.364e-16	81.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,371ZU@32003|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
EH1_k127_8321702_0	1123393.KB891328_gene645	1.622e-131	428.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,1KRFA@119069|Hydrogenophilales	119069|Hydrogenophilales	O	prohibitin homologues	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
EH1_k127_8321702_3	1163617.SCD_n01798	1.892e-17	83.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
EH1_k127_8321702_1	267608.RSc1225	8.514e-123	406.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,1K0TV@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
EH1_k127_8321702_2	1123392.AQWL01000004_gene2687	2.759e-97	319.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,1KRBE@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
EH1_k127_8336109_2	305700.B447_16186	9.74e-112	366.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KU6A@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
EH1_k127_8336109_1	754477.Q7C_863	1.43e-136	445.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46072@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
EH1_k127_8336109_0	1163617.SCD_n02480	1.24e-198	625.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
EH1_k127_8343624_0	631362.Thi970DRAFT_03295	4.722e-55	207.0	COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,1RRWS@1236|Gammaproteobacteria,1X2I8@135613|Chromatiales	135613|Chromatiales	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
EH1_k127_8346161_2	883126.HMPREF9710_01223	2.612e-09	66.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,1R444@1224|Proteobacteria,2VJPB@28216|Betaproteobacteria,475CW@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HDOD
EH1_k127_8346161_1	713587.THITH_13835	2.443e-49	189.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1WY21@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
EH1_k127_8346161_0	292415.Tbd_2148	4.236e-55	197.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1KRIB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH1_k127_8360137_1	292415.Tbd_0607	1.077e-218	682.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,1KRBE@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
EH1_k127_8360137_0	1123392.AQWL01000008_gene1176	7.592e-290	917.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KS7S@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
EH1_k127_8360137_2	1485544.JQKP01000010_gene838	1.932e-151	484.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,44VB3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
EH1_k127_8363303_1	1120999.JONM01000001_gene1276	1.117e-51	185.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,2KPP0@206351|Neisseriales	206351|Neisseriales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
EH1_k127_8363303_0	1038869.AXAN01000007_gene5697	1.323e-72	254.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,1K6Z7@119060|Burkholderiaceae	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
EH1_k127_8363303_2	1137799.GZ78_00180	6.421e-34	139.0	2EDW0@1|root,337R6@2|Bacteria,1N9FY@1224|Proteobacteria,1T68Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_8367437_2	1163617.SCD_n01945	4.676e-129	427.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
EH1_k127_8367437_3	582744.Msip34_0912	7.357e-11	65.0	COG1918@1|root,COG1918@2|Bacteria,1NA6D@1224|Proteobacteria,2VY9N@28216|Betaproteobacteria,2KN7T@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
EH1_k127_8367437_0	1122236.KB905141_gene1444	2.674e-222	706.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,2KKYE@206350|Nitrosomonadales	206350|Nitrosomonadales	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
EH1_k127_8367437_1	1123392.AQWL01000011_gene2232	4.15e-174	569.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KS3Z@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HATPase_c,HisKA,Hpt,PAS_8,Response_reg
EH1_k127_8374966_0	1320556.AVBP01000002_gene4109	3.856e-142	456.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
EH1_k127_8374966_1	1163617.SCD_n01997	1.062e-134	435.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria	28216|Betaproteobacteria	P	membrane protein, terc	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
EH1_k127_8374966_2	313628.LNTAR_20293	0.000958	45.0	COG2862@1|root,COG2862@2|Bacteria	2|Bacteria	S	Uncharacterized protein family, UPF0114	yqhA	-	-	-	-	-	-	-	-	-	-	-	UPF0114
EH1_k127_8413849_1	1458275.AZ34_07565	5.203e-69	244.0	COG0789@1|root,COG0789@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,4ACBQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
EH1_k127_8413849_2	768671.ThimaDRAFT_1361	2.385e-15	83.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1WYSZ@135613|Chromatiales	135613|Chromatiales	D	PFAM Sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH1_k127_8413849_0	402626.Rpic_2099	1.188e-106	347.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,1K0R8@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
EH1_k127_842884_0	1158756.AQXQ01000012_gene1565	3.565e-140	462.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3
EH1_k127_842884_1	765911.Thivi_0315	2.394e-08	56.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,1SBPR@1236|Gammaproteobacteria,1WY4R@135613|Chromatiales	135613|Chromatiales	NT	CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
EH1_k127_8450215_6	1163617.SCD_n01473	8.464e-40	160.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM YCII-related	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
EH1_k127_8450215_5	292415.Tbd_1529	3.416e-71	246.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,1KRP3@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Intracellular septation protein A	-	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
EH1_k127_8450215_2	580332.Slit_1630	7.702e-95	320.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
EH1_k127_8450215_4	261292.Nit79A3_3414	8.479e-85	291.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,3729G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
EH1_k127_8450215_3	1163617.SCD_n01477	6.102e-86	290.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
EH1_k127_8450215_1	1163617.SCD_n01478	5.767e-225	700.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
EH1_k127_8450215_0	1001585.MDS_1261	0.0	1031.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1YE1W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338,ko:K08675	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03029	-	-	-	AAA,LON_substr_bdg,Lon_C
EH1_k127_8473599_0	572477.Alvin_0839	0.0	1088.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH1_k127_8473599_1	265072.Mfla_1183	6.669e-173	567.0	COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KM09@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
EH1_k127_8473599_2	279714.FuraDRAFT_1804	1.857e-34	136.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,2VJPB@28216|Betaproteobacteria,2KS3Y@206351|Neisseriales	206351|Neisseriales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD
EH1_k127_8487538_0	1163617.SCD_n01984	1.748e-177	589.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
EH1_k127_8487538_1	1163617.SCD_n02085	4.768e-33	133.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,2W4VG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH1_k127_8487538_2	414684.RC1_1528	1.093e-16	83.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2JQAY@204441|Rhodospirillales	204441|Rhodospirillales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
EH1_k127_8487538_3	1123367.C666_07460	5.012e-08	58.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
EH1_k127_861610_2	671143.DAMO_1275	1.424e-12	76.0	COG0471@1|root,COG0471@2|Bacteria,2NPNA@2323|unclassified Bacteria	2|Bacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319,ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47,2.A.47.1	-	-	Na_sulph_symp
EH1_k127_861610_0	1116472.MGMO_97c00020	8.18e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,1N00P@1224|Proteobacteria,1S759@1236|Gammaproteobacteria,1XFIZ@135618|Methylococcales	135618|Methylococcales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
EH1_k127_861610_1	1120999.JONM01000004_gene3547	6.559e-31	123.0	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,2VW65@28216|Betaproteobacteria,2KRZK@206351|Neisseriales	206351|Neisseriales	S	Pathogenicity locus	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
EH1_k127_866458_3	278957.ABEA03000218_gene222	2.156e-16	85.0	COG1028@1|root,COG1028@2|Bacteria,46U4P@74201|Verrucomicrobia,3K749@414999|Opitutae	414999|Opitutae	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH1_k127_866458_2	1123368.AUIS01000010_gene2357	6.661e-69	236.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,2NCV9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
EH1_k127_866458_0	292415.Tbd_0003	0.0	1220.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,1KS2W@119069|Hydrogenophilales	119069|Hydrogenophilales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
EH1_k127_866458_1	62928.azo0002	2.846e-118	390.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KV12@206389|Rhodocyclales	206389|Rhodocyclales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
EH1_k127_872635_1	292415.Tbd_0153	2.144e-12	75.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,1KSUW@119069|Hydrogenophilales	119069|Hydrogenophilales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH1_k127_872635_0	887062.HGR_08099	1.096e-157	508.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,4AD7T@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,HAMP,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9
EH1_k127_885850_1	640081.Dsui_1456	2.586e-176	562.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,2KVJ8@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	FHA,GAF,HD,HD_5
EH1_k127_885850_3	690850.Desaf_2459	2.802e-56	204.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,2M8RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
EH1_k127_885850_2	768671.ThimaDRAFT_3603	1.759e-92	307.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,1X266@135613|Chromatiales	135613|Chromatiales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
EH1_k127_885850_0	640081.Dsui_0580	9.95e-205	644.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,2KVM8@206389|Rhodocyclales	206389|Rhodocyclales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
EH1_k127_886801_1	522306.CAP2UW1_0726	1.178e-75	256.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,1KQ7H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
EH1_k127_886801_3	261292.Nit79A3_1270	6.137e-10	61.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY1Y@28216|Betaproteobacteria,373N5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
EH1_k127_886801_2	1288494.EBAPG3_12780	1.698e-60	214.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
EH1_k127_886801_0	713587.THITH_16200	3.533e-132	425.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1WWM9@135613|Chromatiales	135613|Chromatiales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
EH1_k127_909976_0	1123274.KB899411_gene3136	4.364e-186	590.0	COG1653@1|root,COG1653@2|Bacteria,2J76R@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
EH1_k127_909976_1	573413.Spirs_0934	1.802e-54	194.0	COG1175@1|root,COG1175@2|Bacteria,2J6HF@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
EH1_k127_932917_0	1123392.AQWL01000002_gene1821	3.665e-198	627.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,1KSI1@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
EH1_k127_932917_2	1163617.SCD_n03016	2.645e-94	315.0	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH1_k127_932917_1	314345.SPV1_13844	3.858e-122	394.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria	1224|Proteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
EH1_k127_936612_1	305700.B447_16582	1.286e-15	81.0	COG2732@1|root,COG2732@2|Bacteria,1NB8S@1224|Proteobacteria,2WE8N@28216|Betaproteobacteria,2KX6I@206389|Rhodocyclales	206389|Rhodocyclales	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
EH1_k127_936612_0	582744.Msip34_2343	6.293e-170	544.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KPAT@206350|Nitrosomonadales	206350|Nitrosomonadales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH1_k127_945654_1	1121035.AUCH01000001_gene1966	8.284e-114	372.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KUBN@206389|Rhodocyclales	206389|Rhodocyclales	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH1_k127_945654_0	1163617.SCD_n00737	3.371e-166	557.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
EH1_k127_945654_2	640081.Dsui_0118	2.103e-48	174.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,2KWQF@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
EH1_k127_945654_3	1121035.AUCH01000016_gene2231	3.31e-36	149.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,2VNG3@28216|Betaproteobacteria,2KVTI@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
## 2462 queries scanned
## Total time (seconds): 36.87374782562256
## Rate: 66.77 q/s