## Wed Oct 16 11:19:53 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/EH2_bin.4.fa -m mmseqs --itype genome -o EH2_bin.4 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/EH2_bin.4 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
EH2_k127_1013274_0	1123368.AUIS01000009_gene2455	2.065e-249	784.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,2NC0P@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Domain of unknown function (DUF3458_C) ARM repeats	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
EH2_k127_1013274_1	1144319.PMI16_02735	6.172e-168	538.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,4724D@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
EH2_k127_1028690_1	1121918.ARWE01000001_gene2226	5.758e-57	203.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
EH2_k127_1028690_0	1116472.MGMO_61c00030	8.978e-128	417.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
EH2_k127_1028690_2	697282.Mettu_1930	1.442e-05	49.0	COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,1XFBG@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
EH2_k127_103882_1	1132855.KB913035_gene1595	6.856e-20	89.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2VJDE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
EH2_k127_103882_0	1132855.KB913035_gene1594	1.625e-72	247.0	COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,2VIGY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NosL family	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
EH2_k127_103882_2	1123392.AQWL01000008_gene1249	8.55e-13	72.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VN77@28216|Betaproteobacteria,1KS6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_1070737_1	1177181.T9A_01218	4.597e-32	131.0	COG0695@1|root,COG0695@2|Bacteria,1N12W@1224|Proteobacteria,1SB6J@1236|Gammaproteobacteria,1XQX0@135619|Oceanospirillales	135619|Oceanospirillales	O	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
EH2_k127_1070737_0	1121935.AQXX01000109_gene480	0.0	1454.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XHSN@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
EH2_k127_1070737_2	1161401.ASJA01000002_gene2626	3.391e-13	70.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2TTGG@28211|Alphaproteobacteria,43WVF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
EH2_k127_1080779_0	1132855.KB913035_gene1600	3.996e-302	934.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2VM8J@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cu-oxidase_3,Cupredoxin_1
EH2_k127_1080779_1	583345.Mmol_0536	1.061e-75	265.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,2KKSE@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_1097985_3	396588.Tgr7_1346	4.771e-41	160.0	COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1X10Q@135613|Chromatiales	135613|Chromatiales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_1097985_1	1279015.KB908454_gene1161	2.02e-60	213.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1Y4AN@135624|Aeromonadales	135624|Aeromonadales	NT	CheW-like domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_1097985_4	1163617.SCD_n01644	1.089e-05	53.0	2EQYD@1|root,33II1@2|Bacteria,1NHV5@1224|Proteobacteria,2VXZK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
EH2_k127_1097985_2	1429916.X566_18760	3.566e-42	158.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,3JYSH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ArsC family	MA20_27840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
EH2_k127_1097985_0	2340.JV46_12780	1.445e-143	460.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1J7WB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0158	Hexapep,Hexapep_2,THDPS_N_2
EH2_k127_1101751_1	1190603.AJYD01000005_gene4041	5.318e-75	258.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XTEX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_1101751_0	1415778.JQMM01000001_gene709	1.09e-87	301.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1J64R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle	rsmC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
EH2_k127_1120692_1	1163617.SCD_n01931	7.326e-23	100.0	COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_1120692_0	292415.Tbd_2012	1.191e-283	887.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
EH2_k127_112382_0	1163617.SCD_n02017	2.456e-208	659.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH2_k127_1149707_0	396588.Tgr7_2119	2.221e-160	513.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH2_k127_1149707_3	1187848.AJYQ01000039_gene3421	1.456e-13	75.0	2C4GN@1|root,2ZHR0@2|Bacteria,1P917@1224|Proteobacteria,1STX2@1236|Gammaproteobacteria,1XY3H@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
EH2_k127_1149707_1	870187.Thini_0114	4.1e-139	446.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1149707_2	572477.Alvin_2493	2.682e-63	218.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1WWUS@135613|Chromatiales	135613|Chromatiales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
EH2_k127_1150844_3	290398.Csal_3315	2.084e-12	67.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales	135619|Oceanospirillales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
EH2_k127_1150844_0	396588.Tgr7_3318	1.453e-172	557.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
EH2_k127_1150844_1	449447.MAE_34020	2.971e-29	118.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
EH2_k127_1150844_2	2340.JV46_22910	1.81e-16	81.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1J74P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
EH2_k127_115318_0	1163617.SCD_n02239	7.391e-227	715.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
EH2_k127_1154212_2	765910.MARPU_15940	4.673e-47	175.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales	135613|Chromatiales	S	Sterol-binding domain protein	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
EH2_k127_1154212_1	870187.Thini_1765	2.028e-125	404.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,45ZTM@72273|Thiotrichales	72273|Thiotrichales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
EH2_k127_1154212_3	582744.Msip34_1997	3.002e-46	171.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,2KMR5@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
EH2_k127_1154212_0	631362.Thi970DRAFT_02527	9.963e-148	473.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
EH2_k127_1171834_3	765913.ThidrDRAFT_1709	3.761e-21	99.0	28P01@1|root,2ZBWR@2|Bacteria,1RB5K@1224|Proteobacteria,1S2PB@1236|Gammaproteobacteria,1WXYS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1171834_0	2340.JV46_14690	2.718e-96	322.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1J4XC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0084 Mg-dependent DNase	ycfH	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_1171834_1	1049564.TevJSym_bc00220	1.257e-50	181.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1J6FI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	PilZ domain	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
EH2_k127_1171834_2	857087.Metme_3486	4.913e-46	176.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XDVJ@135618|Methylococcales	135618|Methylococcales	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
EH2_k127_1187874_0	391615.ABSJ01000026_gene111	3.09e-143	465.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1J8Z4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,Lactamase_B_2
EH2_k127_1187874_1	1260251.SPISAL_03945	3.094e-26	109.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales	135613|Chromatiales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
EH2_k127_1190610_2	765912.Thimo_1923	1.097e-24	105.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1WYKM@135613|Chromatiales	135613|Chromatiales	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
EH2_k127_1190610_1	2340.JV46_15610	1.354e-53	191.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1J6F3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
EH2_k127_1190610_0	572477.Alvin_0792	1.642e-200	638.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
EH2_k127_1190610_4	153948.NAL212_2311	7.044e-08	56.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,373QW@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
EH2_k127_1190610_3	323261.Noc_0722	4.458e-09	62.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
EH2_k127_1198887_3	1049564.TevJSym_ap00270	6.109e-82	277.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1J5GV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_1198887_0	43989.cce_2243	9.495e-135	462.0	COG5001@1|root,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3KG35@43988|Cyanothece	1117|Cyanobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_1198887_2	396588.Tgr7_1860	8.099e-104	344.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales	135613|Chromatiales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
EH2_k127_1198887_1	396588.Tgr7_1859	1.459e-125	413.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1WWXT@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_1198887_6	1869.MB27_12290	1.172e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2IFAN@201174|Actinobacteria,4DDVA@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
EH2_k127_1198887_5	765913.ThidrDRAFT_1703	5.504e-52	188.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria,1WYAX@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1198887_4	1415779.JOMH01000001_gene2534	1.26e-76	262.0	COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,1X8U8@135614|Xanthomonadales	135614|Xanthomonadales	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
EH2_k127_1209835_1	287.DR97_2975	3.176e-49	181.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1YE97@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
EH2_k127_1209835_0	396588.Tgr7_0191	2.788e-252	792.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
EH2_k127_1210267_2	412965.COSY_0804	2.985e-09	57.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	tRNA methyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	ThiI,tRNA_Me_trans
EH2_k127_1210267_0	1123401.JHYQ01000012_gene2890	3.556e-174	548.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4604S@72273|Thiotrichales	72273|Thiotrichales	J	glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
EH2_k127_1210267_1	1123399.AQVE01000001_gene551	2.505e-23	102.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
EH2_k127_1215677_1	1163617.SCD_n02547	1.409e-50	184.0	COG0526@1|root,COG0526@2|Bacteria,1MZ9B@1224|Proteobacteria,2VV4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_1215677_0	1163617.SCD_n02548	2.126e-124	404.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
EH2_k127_1234056_3	1049564.TevJSym_aa00850	7.4e-34	136.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J4H6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
EH2_k127_1234056_1	1121935.AQXX01000106_gene567	1.868e-94	314.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XH6V@135619|Oceanospirillales	135619|Oceanospirillales	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
EH2_k127_1234056_0	395493.BegalDRAFT_1175	5.497e-129	419.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,4605U@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
EH2_k127_1234056_2	1116472.MGMO_43c00310	6.366e-39	150.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales	135618|Methylococcales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_1234331_0	287.DR97_4678	2.538e-183	587.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1YDCE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
EH2_k127_1234331_5	713586.KB900536_gene821	1.602e-36	147.0	28JN1@1|root,2Z9EG@2|Bacteria,1R8TZ@1224|Proteobacteria,1S1S0@1236|Gammaproteobacteria,1WXT2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1234331_1	338963.Pcar_0271	3.718e-102	347.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,43UX8@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
EH2_k127_1234331_4	113355.CM001775_gene3194	1.476e-42	171.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,Response_reg
EH2_k127_1234331_2	391615.ABSJ01000005_gene588	1.9e-101	342.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1J5KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
EH2_k127_1234331_3	1049564.TevJSym_an00020	1.211e-60	220.0	28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S2GT@1236|Gammaproteobacteria,1JBSH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3549)	SO1618	-	-	-	-	-	-	-	-	-	-	-	DUF3549
EH2_k127_125808_0	1158762.KB898039_gene1706	6.206e-69	238.0	COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg
EH2_k127_125808_1	1158762.KB898039_gene1707	2.165e-59	208.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1WYTZ@135613|Chromatiales	135613|Chromatiales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_125808_3	1158146.KB907125_gene2347	9.361e-18	87.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Hpt,Response_reg
EH2_k127_125808_2	349521.HCH_04142	1.701e-52	192.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1NMCM@1224|Proteobacteria,1SPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
EH2_k127_1268406_3	472759.Nhal_0500	6.581e-119	387.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH2_k127_1268406_4	391615.ABSJ01000032_gene731	3.282e-94	317.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1JAGN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH2_k127_1268406_5	1121940.AUDZ01000004_gene2585	1.25e-08	61.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SHDB@1236|Gammaproteobacteria,1XMNG@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
EH2_k127_1268406_1	1163409.UUA_01899	7.759e-145	464.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
EH2_k127_1268406_0	187272.Mlg_2187	2.859e-151	487.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
EH2_k127_1268406_2	396588.Tgr7_0774	1.388e-130	419.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
EH2_k127_1278155_0	1123401.JHYQ01000024_gene1295	0.0	1244.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH2_k127_1278636_2	765911.Thivi_1337	8.715e-95	315.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1WWM0@135613|Chromatiales	135613|Chromatiales	P	extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
EH2_k127_1278636_0	396588.Tgr7_0454	1.013e-231	729.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1WWS0@135613|Chromatiales	135613|Chromatiales	P	inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH2_k127_1278636_1	396588.Tgr7_0453	9.543e-142	458.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1WX9E@135613|Chromatiales	135613|Chromatiales	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
EH2_k127_1289080_1	1318628.MARLIPOL_01760	2.432e-79	269.0	COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,465MI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
EH2_k127_1289080_0	1121374.KB891588_gene3366	1.49e-124	406.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
EH2_k127_1289080_2	519989.ECTPHS_08928	9.335e-20	91.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1X2AK@135613|Chromatiales	135613|Chromatiales	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
EH2_k127_1312113_0	396588.Tgr7_3089	2.694e-317	980.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WX8J@135613|Chromatiales	135613|Chromatiales	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
EH2_k127_1322209_4	713587.THITH_12885	2.488e-60	211.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
EH2_k127_1322209_2	1123518.ARWI01000001_gene272	1.975e-124	430.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
EH2_k127_1322209_5	1279017.AQYJ01000026_gene67	6.29e-55	197.0	2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria,46BPI@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1322209_1	1232410.KI421425_gene1550	3.64e-210	672.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1322209_0	1279017.AQYJ01000026_gene65	0.0	1073.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
EH2_k127_1322209_7	1279017.AQYJ01000026_gene64	4.79e-49	182.0	COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4697B@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8
EH2_k127_1322209_9	1279017.AQYJ01000026_gene63	4.073e-27	113.0	2EQ5T@1|root,33HS3@2|Bacteria,1NMTN@1224|Proteobacteria,1SIGB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1322209_3	1232410.KI421425_gene1546	3.472e-92	307.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH2_k127_1322209_6	1232410.KI421425_gene1545	1.571e-54	195.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
EH2_k127_1322209_8	1232410.KI421425_gene1544	6.414e-44	165.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
EH2_k127_1322209_10	1177154.Y5S_01707	5.155e-05	48.0	COG0810@1|root,COG0810@2|Bacteria,1RJ7J@1224|Proteobacteria,1S817@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
EH2_k127_1336669_0	1485545.JQLW01000010_gene1512	1.808e-152	503.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria	1224|Proteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	bicA	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
EH2_k127_1343175_0	1565129.JSFF01000005_gene2384	1.874e-137	462.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q95S@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
EH2_k127_134783_0	1212548.B381_21466	1.276e-137	460.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1Z07I@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
EH2_k127_134783_2	349124.Hhal_1785	2.314e-25	116.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,1RYAA@1236|Gammaproteobacteria,1WXSC@135613|Chromatiales	135613|Chromatiales	S	PFAM Pentapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH2_k127_134783_3	1441629.PCH70_10330	1.919e-13	74.0	COG0695@1|root,COG0695@2|Bacteria,1N6ZT@1224|Proteobacteria,1SD1U@1236|Gammaproteobacteria,1Z7RT@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	O	Glutaredoxin	nrdH	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
EH2_k127_134783_1	314345.SPV1_06839	4.012e-48	177.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH2_k127_134886_0	649638.Trad_2886	4.204e-145	472.0	COG1057@1|root,COG1057@2|Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
EH2_k127_135334_3	396588.Tgr7_1229	2.213e-91	308.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
EH2_k127_135334_1	713586.KB900536_gene925	9.224e-118	385.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1WWI6@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
EH2_k127_135334_4	865861.AZSU01000003_gene2092	1.228e-47	191.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,36DU5@31979|Clostridiaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH2_k127_135334_0	1163617.SCD_n00189	2.683e-155	505.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
EH2_k127_135334_2	335283.Neut_0990	2.963e-114	376.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2WGYA@28216|Betaproteobacteria,374QX@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_1357867_1	1123517.JOMR01000001_gene1957	8.789e-66	228.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,45ZQR@72273|Thiotrichales	72273|Thiotrichales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
EH2_k127_1357867_0	1049564.TevJSym_ag01050	5.562e-76	257.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1J5V6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
EH2_k127_1357867_2	519989.ECTPHS_01149	1.245e-20	97.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1WWDN@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
EH2_k127_137040_3	1144342.PMI40_03510	1.429e-40	151.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,476M8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
EH2_k127_137040_0	477184.KYC_22286	3.577e-230	730.0	COG2267@1|root,COG4870@1|root,COG2267@2|Bacteria,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
EH2_k127_137040_2	2340.JV46_06720	1.27e-43	162.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,1SC6J@1236|Gammaproteobacteria,1J6W2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
EH2_k127_137040_4	1163617.SCD_n02594	6.956e-28	118.0	2ECQ3@1|root,336MT@2|Bacteria,1NB5U@1224|Proteobacteria,2VVY5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1376190_3	156889.Mmc1_2535	1.485e-12	72.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	MA20_34190	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_1376190_4	76114.ebA6722	4.872e-12	75.0	COG0784@1|root,COG4191@1|root,COG4192@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG4192@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,Response_reg
EH2_k127_1376190_2	983917.RGE_33920	3.699e-105	366.0	COG0784@1|root,COG2202@1|root,COG3852@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KNP0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
EH2_k127_1376190_1	1123392.AQWL01000005_gene2918	3.065e-119	394.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria	28216|Betaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
EH2_k127_1376190_0	1163617.SCD_n00904	3.157e-171	558.0	COG2199@1|root,COG2200@1|root,COG5002@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WHDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
EH2_k127_1379042_2	765911.Thivi_1808	2.566e-54	193.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales	135613|Chromatiales	L	hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_1379042_0	292415.Tbd_2732	4.302e-77	268.0	COG3850@1|root,COG3850@2|Bacteria,1N23T@1224|Proteobacteria,2VQFG@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	PilJ
EH2_k127_1379042_1	1123514.KB905899_gene1277	3.323e-56	203.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1S11C@1236|Gammaproteobacteria,460N0@72273|Thiotrichales	72273|Thiotrichales	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
EH2_k127_1379042_3	1123514.KB905899_gene1276	1.99e-44	164.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
EH2_k127_1396381_1	1453501.JELR01000001_gene1901	9.641e-108	365.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
EH2_k127_1396381_2	1123399.AQVE01000010_gene3285	1.473e-86	295.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,460H3@72273|Thiotrichales	72273|Thiotrichales	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
EH2_k127_1396381_0	1123401.JHYQ01000009_gene2239	6.32e-114	373.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales	72273|Thiotrichales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
EH2_k127_1396381_3	203122.Sde_3647	1.284e-78	267.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
EH2_k127_1396381_4	1026882.MAMP_02949	1.178e-34	134.0	2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_140634_0	1410619.SRDD_35890	9.221e-163	522.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,401Y7@613|Serratia	1236|Gammaproteobacteria	L	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C	polB	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1
EH2_k127_141311_0	90813.JQMT01000001_gene1639	4.533e-140	449.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
EH2_k127_1426555_1	580332.Slit_1127	1.135e-170	552.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor, type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
EH2_k127_1426555_4	2340.JV46_05470	1.546e-70	246.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
EH2_k127_1426555_8	2340.JV46_05470	9.152e-45	167.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
EH2_k127_1426555_10	292415.Tbd_0557	8.983e-32	128.0	2C0CP@1|root,32SP5@2|Bacteria,1N5DU@1224|Proteobacteria,2VU5I@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1426555_2	580332.Slit_1125	1.354e-136	438.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,44UZJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ATPase associated with various cellular activities AAA_5	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
EH2_k127_1426555_0	2340.JV46_05520	6.049e-253	784.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1J4TK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	norB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
EH2_k127_1426555_5	1122599.AUGR01000017_gene2978	5.412e-69	237.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1XKAN@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome c	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
EH2_k127_1426555_9	28229.ND2E_1279	1.858e-35	141.0	COG2703@1|root,COG2703@2|Bacteria,1MY70@1224|Proteobacteria,1S6H9@1236|Gammaproteobacteria,2Q833@267889|Colwelliaceae	1236|Gammaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
EH2_k127_1426555_6	395493.BegalDRAFT_2974	4.876e-49	187.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,463EC@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_1426555_7	391615.ABSJ01000034_gene1067	1.674e-46	170.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_1426555_11	395493.BegalDRAFT_2971	7.892e-24	108.0	COG0835@1|root,COG0835@2|Bacteria,1NF0B@1224|Proteobacteria,1SD1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	CheW-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
EH2_k127_1426555_3	207954.MED92_05398	7.731e-112	389.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales	135619|Oceanospirillales	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
EH2_k127_1435742_3	1298608.JCM18900_11148	1.136e-19	98.0	COG2373@1|root,COG2373@2|Bacteria,1QU7D@1224|Proteobacteria,1T1PT@1236|Gammaproteobacteria,3NTK7@468|Moraxellaceae	1236|Gammaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
EH2_k127_1435742_0	1049564.TevJSym_as00390	1.964e-191	607.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	gtrB	-	-	-	-	-	-	-	-	-	-	-	DctM
EH2_k127_1435742_1	765912.Thimo_0632	6.631e-53	195.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1WXYX@135613|Chromatiales	135613|Chromatiales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
EH2_k127_1435742_2	1158756.AQXQ01000012_gene2018	6.756e-40	149.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales	135613|Chromatiales	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
EH2_k127_1444624_2	857087.Metme_4005	7.498e-53	191.0	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,1S8HH@1236|Gammaproteobacteria,1XF8H@135618|Methylococcales	135618|Methylococcales	K	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
EH2_k127_1444624_1	1122135.KB893166_gene3055	8.77e-62	218.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2U84D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator AsnC family	nirH	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
EH2_k127_1444624_0	1255043.TVNIR_1648	1.24e-106	349.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales	135613|Chromatiales	S	Radical SAM superfamily	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
EH2_k127_1447496_0	519989.ECTPHS_02821	9.017e-275	852.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
EH2_k127_1447496_1	396588.Tgr7_2239	3.746e-44	164.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,1S20Q@1236|Gammaproteobacteria,1WY8G@135613|Chromatiales	135613|Chromatiales	L	pfam nudix	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
EH2_k127_145849_4	1041159.AZUW01000007_gene5276	4.449e-114	369.0	COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,2TU0Z@28211|Alphaproteobacteria,4BAQ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
EH2_k127_145849_1	366394.Smed_5203	1.968e-197	618.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TUZN@28211|Alphaproteobacteria,4B8VT@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3,2.1.3.6	ko:K00611,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH2_k127_145849_3	1500257.JQNM01000001_gene3358	1.721e-154	494.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,2TVMD@28211|Alphaproteobacteria,4BA59@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH2_k127_145849_2	366394.Smed_5198	1.912e-194	615.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2TRWS@28211|Alphaproteobacteria,4BBUA@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	amino acid	-	-	-	ko:K03294,ko:K03759	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
EH2_k127_145849_5	236097.ADG881_1929	8.33e-93	314.0	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1XHP1@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_145849_0	396588.Tgr7_1245	4.86e-248	771.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1WWEG@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
EH2_k127_1470855_3	349521.HCH_03018	2.038e-32	138.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XHHM@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_1470855_0	1163617.SCD_n02017	9.99e-268	835.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH2_k127_1470855_1	1163617.SCD_n01585	4.217e-239	750.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,2VZ32@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH2_k127_1470855_2	580332.Slit_1776	2.475e-49	192.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
EH2_k127_1470855_4	85643.Tmz1t_3051	3.235e-30	121.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2VVR6@28216|Betaproteobacteria,2KXHZ@206389|Rhodocyclales	206389|Rhodocyclales	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
EH2_k127_147695_13	1122614.JHZF01000013_gene3463	1.54e-32	130.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH2_k127_147695_10	1415780.JPOG01000001_gene3277	5.135e-72	255.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,1X5D0@135614|Xanthomonadales	135614|Xanthomonadales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
EH2_k127_147695_8	1380394.JADL01000016_gene435	1.082e-77	274.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,2JPDC@204441|Rhodospirillales	204441|Rhodospirillales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
EH2_k127_147695_17	1123499.KB908026_gene1734	2.517e-08	66.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KPU9@206351|Neisseriales	206351|Neisseriales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
EH2_k127_147695_9	1132855.KB913035_gene1382	4.371e-72	248.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2VJPT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_147695_2	1049564.TevJSym_ac00480	3.089e-188	598.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
EH2_k127_147695_0	396588.Tgr7_0222	7.772e-231	724.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
EH2_k127_147695_1	1134474.O59_003174	2.695e-195	620.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,1RPYD@1236|Gammaproteobacteria,1FFS5@10|Cellvibrio	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
EH2_k127_147695_6	713586.KB900536_gene2354	1.271e-91	308.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
EH2_k127_147695_14	1158760.AQXP01000055_gene1371	2.928e-21	98.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH2_k127_147695_15	85643.Tmz1t_0913	9.049e-19	89.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,2KX8N@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH2_k127_147695_12	1049564.TevJSym_bh00270	1.895e-46	169.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1J6FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
EH2_k127_147695_11	76114.ebB39	1.129e-57	202.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,2KWD3@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
EH2_k127_147695_3	697282.Mettu_1666	1.404e-134	433.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XE1I@135618|Methylococcales	135618|Methylococcales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH2_k127_147695_4	857087.Metme_4198	3.583e-123	398.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1XETV@135618|Methylococcales	135618|Methylococcales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH2_k127_147695_7	998674.ATTE01000001_gene3586	7.607e-88	294.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,460FG@72273|Thiotrichales	72273|Thiotrichales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
EH2_k127_147695_5	713586.KB900536_gene2346	1.427e-104	342.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales	135613|Chromatiales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
EH2_k127_147695_18	396588.Tgr7_0635	0.0001959	47.0	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1484_5	1117647.M5M_19065	4.38e-63	237.0	COG2198@1|root,COG2206@1|root,COG2198@2|Bacteria,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,1RSQ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Hpt
EH2_k127_1484_2	491952.Mar181_1982	2.432e-146	476.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XI0Q@135619|Oceanospirillales	135619|Oceanospirillales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
EH2_k127_1484_1	1123368.AUIS01000022_gene1060	3.883e-165	537.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,2NBV0@225057|Acidithiobacillales	225057|Acidithiobacillales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
EH2_k127_1484_9	2340.JV46_25850	1.93e-28	116.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1J6V1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsO	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
EH2_k127_1484_8	1049564.TevJSym_ak00760	3.29e-32	130.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1RNAT@1236|Gammaproteobacteria,1J9A2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	PTS system fructose IIA component	manX	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659	2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	iAPECO1_1312.APECO1_874,iECOK1_1307.ECOK1_1934,iECS88_1305.ECS88_1869,iPC815.YPO1758,iUMN146_1321.UM146_08085,iUTI89_1310.UTI89_C2014	EIIA-man,PTSIIB_sorb
EH2_k127_1484_3	713586.KB900536_gene1422	4.817e-99	331.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
EH2_k127_1484_4	396588.Tgr7_0723	4.446e-93	315.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
EH2_k127_1484_6	187272.Mlg_2232	1.563e-43	163.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1WYAA@135613|Chromatiales	135613|Chromatiales	G	PTS IIA-like nitrogen-regulatory protein PtsN	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
EH2_k127_1484_7	713586.KB900536_gene1419	1.633e-34	134.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales	135613|Chromatiales	J	Sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
EH2_k127_1484_0	1112217.PPL19_05705	2.824e-170	547.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
EH2_k127_1488900_3	1123393.KB891316_gene2122	1.144e-16	79.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KT21@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH2_k127_1488900_2	1234364.AMSF01000033_gene433	1.491e-30	124.0	29RZY@1|root,30D49@2|Bacteria,1N736@1224|Proteobacteria,1ST46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1488900_0	1123393.KB891316_gene2123	7.609e-166	529.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2W9BF@28216|Betaproteobacteria,1KT6Y@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
EH2_k127_1488900_1	765912.Thimo_1059	8.373e-53	195.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1WXEC@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
EH2_k127_1488900_4	96561.Dole_2423	8.218e-05	50.0	COG3103@1|root,COG3103@2|Bacteria,1R4IV@1224|Proteobacteria,42UPZ@68525|delta/epsilon subdivisions,2WQDF@28221|Deltaproteobacteria,2MKNS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1507881_0	765913.ThidrDRAFT_3891	6.859e-247	770.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
EH2_k127_1512277_1	1163617.SCD_n01825	2.659e-70	248.0	COG2199@1|root,COG2199@2|Bacteria,1QXGC@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH2_k127_1512277_4	392500.Swoo_4316	1.055e-19	92.0	2EICS@1|root,33C43@2|Bacteria,1NIAI@1224|Proteobacteria,1SGPY@1236|Gammaproteobacteria,2QCPZ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1512277_3	1121935.AQXX01000142_gene2322	1.33e-33	130.0	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,1XM1Y@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF5062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5062
EH2_k127_1512277_2	1122194.AUHU01000016_gene1860	8.548e-69	244.0	2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria,466PI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
EH2_k127_1512277_0	1123518.ARWI01000001_gene272	3.403e-83	289.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
EH2_k127_1528011_0	1163617.SCD_n02228	1.169e-137	440.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
EH2_k127_1531694_2	557598.LHK_01405	4.882e-30	119.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KPY4@206351|Neisseriales	206351|Neisseriales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
EH2_k127_1531694_0	582744.Msip34_2252	3.859e-74	258.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KMU4@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
EH2_k127_1531694_1	1121116.KB894767_gene2167	1.053e-39	151.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,4AA9Y@80864|Comamonadaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH2_k127_1542800_0	396588.Tgr7_1759	7.16e-322	995.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1WW4U@135613|Chromatiales	135613|Chromatiales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
EH2_k127_1542800_1	1198232.CYCME_1822	1.26e-176	561.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_1542800_3	857087.Metme_0228	1.849e-32	132.0	COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1RVW2@1236|Gammaproteobacteria,1XFEW@135618|Methylococcales	135618|Methylococcales	T	Universal stress protein	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
EH2_k127_1542800_2	396588.Tgr7_1549	2.672e-125	407.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales	135613|Chromatiales	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH2_k127_1542800_4	396588.Tgr7_1280	3.317e-25	115.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria	1224|Proteobacteria	L	double-strand break repair protein AddB	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
EH2_k127_1543071_3	472759.Nhal_1045	1.755e-61	216.0	COG1451@1|root,COG1451@2|Bacteria,1R8SX@1224|Proteobacteria,1RNX7@1236|Gammaproteobacteria,1WYNF@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
EH2_k127_1543071_0	1163617.SCD_n02315	0.0	1022.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_1543071_1	1120963.KB894491_gene1102	5.652e-195	618.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,2Q0P3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_1543071_2	1163409.UUA_16885	1.428e-142	458.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1X38H@135614|Xanthomonadales	135614|Xanthomonadales	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
EH2_k127_1543071_4	316275.VSAL_I0994	1.488e-51	186.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XWWW@135623|Vibrionales	135623|Vibrionales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
EH2_k127_1543071_5	1235457.C404_21280	1.313e-08	57.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,1K0DE@119060|Burkholderiaceae	28216|Betaproteobacteria	P	CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
EH2_k127_1551395_5	880073.Calab_2902	7.015e-06	52.0	2AAUM@1|root,3107D@2|Bacteria,2NRTT@2323|unclassified Bacteria	2|Bacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
EH2_k127_1551395_2	653733.Selin_0436	1.329e-83	293.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
EH2_k127_1551395_4	314282.PCNPT3_07225	8.321e-68	238.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,2QHZ3@267894|Psychromonadaceae	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
EH2_k127_1551395_0	396588.Tgr7_1531	9.703e-192	608.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
EH2_k127_1551395_1	1453501.JELR01000001_gene2048	1.474e-105	346.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2376	Methyltransf_23
EH2_k127_1551395_3	396588.Tgr7_1529	6.991e-73	252.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1WXXM@135613|Chromatiales	135613|Chromatiales	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH2_k127_1551541_5	161528.ED21_23761	4.682e-153	495.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2UBMV@28211|Alphaproteobacteria,2K6P2@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1551541_4	1278309.KB907099_gene2930	1.989e-167	541.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,1T3FX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
EH2_k127_1551541_13	1535422.ND16A_1225	2.7e-52	194.0	COG0492@1|root,COG0492@2|Bacteria,1R12A@1224|Proteobacteria	1224|Proteobacteria	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1551541_10	1298593.TOL_2850	3.02e-61	214.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XJM2@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
EH2_k127_1551541_14	1517416.IDAT_04565	1.18e-50	184.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,2QG4K@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
EH2_k127_1551541_2	1026882.MAMP_00339	6.315e-233	726.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,45ZRM@72273|Thiotrichales	72273|Thiotrichales	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH2_k127_1551541_6	1182590.BN5_03411	3.791e-98	333.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1YF19@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Methylates ribosomal protein L11	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
EH2_k127_1551541_17	1151127.KB906333_gene3955	1.319e-32	139.0	COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1YP0U@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
EH2_k127_1551541_1	1049564.TevJSym_as00440	1.566e-256	808.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4ZV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH2_k127_1551541_15	398767.Glov_2928	2.159e-40	151.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
EH2_k127_1551541_0	765914.ThisiDRAFT_0399	1.207e-290	898.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH2_k127_1551541_3	1123393.KB891326_gene124	5.07e-224	701.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VHVU@28216|Betaproteobacteria,1KSGU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	GTP-binding GTPase Middle Region	-	-	-	-	-	-	-	-	-	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
EH2_k127_1551541_11	1121015.N789_03325	1.165e-55	200.0	COG0454@1|root,COG0456@2|Bacteria,1RH4M@1224|Proteobacteria,1SB9M@1236|Gammaproteobacteria,1X5YB@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
EH2_k127_1551541_16	1163617.SCD_n00546	2.706e-37	143.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1551541_12	583345.Mmol_1191	3.53e-53	191.0	COG2731@1|root,COG2731@2|Bacteria,1RJ5F@1224|Proteobacteria,2VTSG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
EH2_k127_1551541_7	395494.Galf_1854	2.071e-96	325.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2WFRY@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
EH2_k127_1551541_9	658187.LDG_7551	2.232e-71	245.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,1S55P@1236|Gammaproteobacteria,1JG08@118969|Legionellales	118969|Legionellales	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
EH2_k127_1551541_8	1049564.TevJSym_as00320	1.011e-93	315.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_1560729_5	1121403.AUCV01000012_gene4121	2.975e-05	49.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,42PMI@68525|delta/epsilon subdivisions,2WN46@28221|Deltaproteobacteria,2MJXV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
EH2_k127_1560729_3	247634.GPB2148_1960	2.073e-58	213.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S5VC@1236|Gammaproteobacteria,1J74T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
EH2_k127_1560729_2	1120999.JONM01000016_gene228	5.609e-60	218.0	COG4254@1|root,COG4254@2|Bacteria,1MYBD@1224|Proteobacteria,2VSSC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,SPOR
EH2_k127_1560729_1	395494.Galf_2291	6.529e-126	409.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,44V8I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
EH2_k127_1560729_0	243233.MCA0683	6.827e-217	690.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XDXB@135618|Methylococcales	135618|Methylococcales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
EH2_k127_1560729_4	765910.MARPU_13765	2.115e-34	136.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1WYM1@135613|Chromatiales	135613|Chromatiales	U	TIGRFAM preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
EH2_k127_1564633_0	765912.Thimo_0389	1.544e-145	471.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1WWRH@135613|Chromatiales	1236|Gammaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	Dabb,F_bP_aldolase
EH2_k127_1564633_1	1288494.EBAPG3_6540	1.895e-54	192.0	COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,2VIA8@28216|Betaproteobacteria,372HD@32003|Nitrosomonadales	28216|Betaproteobacteria	O	AAA domain (dynein-related subfamily)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
EH2_k127_1566010_0	658086.HMPREF0994_04365	3.936e-155	504.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,27S1C@186928|unclassified Lachnospiraceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
EH2_k127_1590568_1	1123393.KB891317_gene2372	4.75e-90	298.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,2W1W6@28216|Betaproteobacteria,1KSRH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
EH2_k127_1590568_0	1123392.AQWL01000009_gene1117	0.0	1271.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,1KS3F@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
EH2_k127_159336_0	1123401.JHYQ01000009_gene2263	1.056e-253	788.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,46017@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
EH2_k127_159336_2	472759.Nhal_3945	2.646e-48	176.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
EH2_k127_159336_1	506534.Rhein_0224	4.133e-119	392.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1WWG8@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
EH2_k127_1602631_0	765914.ThisiDRAFT_0950	8.286e-127	408.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
EH2_k127_1602631_5	686340.Metal_3321	1.069e-48	177.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1XF9Z@135618|Methylococcales	135618|Methylococcales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
EH2_k127_1602631_4	519989.ECTPHS_13233	2.408e-65	229.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1WXDE@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
EH2_k127_1602631_1	686340.Metal_3323	5.648e-104	342.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XEX5@135618|Methylococcales	135618|Methylococcales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
EH2_k127_1602631_3	396588.Tgr7_2335	3.454e-73	248.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1WXZD@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
EH2_k127_1602631_2	1049564.TevJSym_bu00100	1.301e-93	308.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1J4SH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
EH2_k127_1602631_6	765914.ThisiDRAFT_0944	4.259e-34	136.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1SB9R@1236|Gammaproteobacteria,1WYI2@135613|Chromatiales	135613|Chromatiales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
EH2_k127_1602631_7	1123400.KB904817_gene1449	7.479e-17	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
EH2_k127_1602666_6	1123400.KB904817_gene1449	7.479e-17	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
EH2_k127_1602666_3	1049564.TevJSym_aa00010	9.679e-52	184.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1J66Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
EH2_k127_1602666_1	713586.KB900536_gene1170	8.4e-90	301.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
EH2_k127_1602666_2	1123020.AUIE01000022_gene3177	6.259e-72	248.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1YDRR@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
EH2_k127_1602666_5	396588.Tgr7_2322	3.648e-33	130.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1WYZN@135613|Chromatiales	135613|Chromatiales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
EH2_k127_1602666_0	1232683.ADIMK_0930	1.245e-143	458.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,464EJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
EH2_k127_1602666_4	572477.Alvin_2359	1.344e-44	162.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1WYHJ@135613|Chromatiales	135613|Chromatiales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
EH2_k127_1602666_7	870187.Thini_3317	5.237e-13	68.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
EH2_k127_1604065_0	713586.KB900536_gene2310	7.158e-178	561.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales	135613|Chromatiales	S	Radical SAM superfamily	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
EH2_k127_1604065_1	1304883.KI912532_gene3198	2.464e-70	244.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2VIU7@28216|Betaproteobacteria,2KU6N@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
EH2_k127_1605238_0	765911.Thivi_2999	8.118e-128	417.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_1605238_3	870187.Thini_1599	1.486e-37	146.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,45ZZU@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_1605238_1	754476.Q7A_1270	3.904e-102	341.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,45ZZU@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_1605238_2	519989.ECTPHS_06627	4.637e-43	162.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1WY3H@135613|Chromatiales	135613|Chromatiales	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
EH2_k127_161032_2	697282.Mettu_2015	6.379e-24	103.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1XF09@135618|Methylococcales	135618|Methylococcales	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
EH2_k127_161032_0	1049564.TevJSym_at00140	1.089e-73	253.0	COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1J69Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.1.1.104,4.2.1.109	ko:K08964,ko:K22130	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
EH2_k127_161032_3	1122604.JONR01000012_gene3400	5.83e-12	78.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
EH2_k127_161032_1	323261.Noc_0191	3.061e-62	233.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WYU5@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_1616213_4	1121943.KB899989_gene3309	4.857e-32	128.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
EH2_k127_1616213_2	713586.KB900536_gene2631	4.365e-53	189.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1WYSF@135613|Chromatiales	135613|Chromatiales	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
EH2_k127_1616213_1	1049564.TevJSym_ao00200	7.61e-67	233.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1SE7Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
EH2_k127_1616213_0	765913.ThidrDRAFT_1071	2.527e-89	302.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales	135613|Chromatiales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
EH2_k127_1616213_3	326297.Sama_2824	4.469e-50	183.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,2QBNW@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
EH2_k127_1616213_5	1120953.AUBH01000006_gene2638	2.127e-13	70.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
EH2_k127_1624319_0	2340.JV46_21960	1.066e-264	830.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_1624319_1	1177179.A11A3_06958	2.463e-09	69.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1631030_0	396588.Tgr7_2459	6.491e-104	348.0	COG2199@1|root,COG3706@2|Bacteria,1R76U@1224|Proteobacteria,1S15R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
EH2_k127_1631030_2	1123399.AQVE01000002_gene2431	3.156e-52	186.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
EH2_k127_1631030_1	335543.Sfum_3898	3.286e-95	325.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42NWJ@68525|delta/epsilon subdivisions,2WKW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_1631030_3	768671.ThimaDRAFT_4051	1.411e-09	58.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH2_k127_163251_0	526222.Desal_3699	8.033e-169	542.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42QI6@68525|delta/epsilon subdivisions,2WKX0@28221|Deltaproteobacteria,2M95J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	frzE	-	2.7.13.3	ko:K03407,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH2_k127_163251_1	489825.LYNGBM3L_43700	4.483e-74	261.0	COG2201@1|root,COG2201@2|Bacteria,1G1EA@1117|Cyanobacteria,1H8DX@1150|Oscillatoriales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K13491	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_163251_2	1123242.JH636434_gene5118	1.582e-20	93.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,2IXA6@203682|Planctomycetes	203682|Planctomycetes	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
EH2_k127_1633110_2	713586.KB900536_gene2107	9.123e-36	138.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
EH2_k127_1633110_1	1049564.TevJSym_aa02310	1.989e-191	604.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1J4D1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
EH2_k127_1633110_3	765910.MARPU_14725	3.158e-28	114.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1WZ9Q@135613|Chromatiales	135613|Chromatiales	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
EH2_k127_1633110_4	1247024.JRLH01000006_gene2694	6.514e-06	53.0	2DR0Q@1|root,339PT@2|Bacteria,1NM26@1224|Proteobacteria,1SJC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1633110_0	62928.azo0449	1.462e-196	629.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,2KVGM@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
EH2_k127_16343_6	396588.Tgr7_2713	2.506e-89	307.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
EH2_k127_16343_0	765914.ThisiDRAFT_1432	2.675e-223	711.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
EH2_k127_16343_1	396588.Tgr7_2710	4.529e-146	471.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
EH2_k127_16343_5	1240350.AMZE01000029_gene1835	1.307e-105	351.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1YWSQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
EH2_k127_16343_8	713586.KB900536_gene2644	2.274e-65	232.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales	135613|Chromatiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
EH2_k127_16343_3	1049564.TevJSym_ao00680	3.67e-136	443.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1J4UD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	dacA	GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664	PBP5_C,Peptidase_S11
EH2_k127_16343_4	396588.Tgr7_2706	8.194e-109	359.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
EH2_k127_16343_9	697282.Mettu_1399	1.34e-21	96.0	COG2921@1|root,COG2921@2|Bacteria,1PJDX@1224|Proteobacteria,1THTC@1236|Gammaproteobacteria,1XFN8@135618|Methylococcales	135618|Methylococcales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
EH2_k127_16343_7	396588.Tgr7_2704	7.081e-74	254.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1WX46@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
EH2_k127_16343_2	1298593.TOL_2893	6.234e-146	468.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XHPM@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
EH2_k127_1638649_1	1163617.SCD_n02212	1.855e-50	182.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,2VWDX@28216|Betaproteobacteria	28216|Betaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
EH2_k127_1638649_0	1163617.SCD_n02211	3.493e-158	502.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM Band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
EH2_k127_164532_1	631362.Thi970DRAFT_04877	2.796e-136	444.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_164532_2	305900.GV64_15940	2.142e-83	289.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,1XJGH@135619|Oceanospirillales	135619|Oceanospirillales	V	ABC transporter ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_164532_0	519989.ECTPHS_09088	6.75e-216	676.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales	135613|Chromatiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
EH2_k127_1665577_2	754476.Q7A_669	6.884e-66	233.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,460MG@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
EH2_k127_1665577_5	1173026.Glo7428_0389	1.744e-35	145.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
EH2_k127_1665577_0	1122201.AUAZ01000009_gene2878	3.809e-306	969.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
EH2_k127_1665577_3	1049564.TevJSym_ax00450	3.381e-61	225.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
EH2_k127_1665577_1	765913.ThidrDRAFT_0772	3.462e-237	748.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales	135613|Chromatiales	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
EH2_k127_1665577_4	1123393.KB891326_gene10	1.217e-45	169.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2W93N@28216|Betaproteobacteria,1KTHC@119069|Hydrogenophilales	1224|Proteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
EH2_k127_1673622_0	472759.Nhal_0597	2.628e-93	321.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
EH2_k127_1678224_0	1123508.JH636442_gene4155	3.731e-285	906.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2IX0I@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
EH2_k127_1678224_2	713586.KB900536_gene2263	1.937e-38	149.0	COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1678224_1	713586.KB900536_gene2264	4.559e-113	377.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF302
EH2_k127_1678224_4	1027273.GZ77_14730	3.861e-11	64.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XHUD@135619|Oceanospirillales	135619|Oceanospirillales	L	Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH2_k127_1692467_1	760568.Desku_1015	0.0003691	51.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,261WX@186807|Peptococcaceae	186801|Clostridia	NT	Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_1692467_0	1120999.JONM01000002_gene951	9.248e-43	160.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
EH2_k127_1700667_1	261292.Nit79A3_0661	8.978e-89	293.0	COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2VIAD@28216|Betaproteobacteria,371V0@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
EH2_k127_1700667_0	261292.Nit79A3_0662	4.899e-292	898.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2VH8K@28216|Betaproteobacteria,372JR@32003|Nitrosomonadales	28216|Betaproteobacteria	E	L-serine dehydratase single chain form	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
EH2_k127_1709390_1	396588.Tgr7_0131	6.418e-103	338.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1WWXZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
EH2_k127_1709390_3	519989.ECTPHS_07421	2.104e-59	213.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales	135613|Chromatiales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
EH2_k127_1709390_4	1173028.ANKO01000037_gene3771	2.524e-50	194.0	COG2199@1|root,COG3706@2|Bacteria,1G3NI@1117|Cyanobacteria,1H8P7@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
EH2_k127_1709390_5	1348114.OM33_15580	1.469e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2Q3A4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspV	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_1709390_0	323261.Noc_1217	1.554e-112	370.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH2_k127_1709390_2	396588.Tgr7_0127	7.395e-97	323.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
EH2_k127_1709739_2	519989.ECTPHS_10701	1.598e-13	71.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
EH2_k127_1709739_0	713586.KB900536_gene312	7.631e-195	623.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales	135613|Chromatiales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
EH2_k127_1709739_1	1121374.KB891585_gene2213	5.189e-65	229.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
EH2_k127_1716175_2	404589.Anae109_1481	5.181e-09	64.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
EH2_k127_1716175_0	1122599.AUGR01000016_gene2884	9.427e-95	317.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XHFQ@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
EH2_k127_1716175_1	472759.Nhal_0475	2.617e-40	162.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales	135613|Chromatiales	M	PFAM LppC	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
EH2_k127_1722214_2	713586.KB900536_gene1704	2.274e-146	477.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales	135613|Chromatiales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH2_k127_1722214_1	519989.ECTPHS_03919	1.401e-146	471.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales	135613|Chromatiales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH2_k127_1722214_7	1278309.KB907100_gene2048	9.482e-63	219.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1XK1S@135619|Oceanospirillales	135619|Oceanospirillales	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
EH2_k127_1722214_11	1249627.D779_0656	2.36e-39	150.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1WYAH@135613|Chromatiales	135613|Chromatiales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
EH2_k127_1722214_5	1049564.TevJSym_bn00100	2.87e-68	236.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1J62V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
EH2_k127_1722214_8	1500890.JQNL01000001_gene943	2.406e-60	219.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1X3C8@135614|Xanthomonadales	135614|Xanthomonadales	M	tonb protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
EH2_k127_1722214_4	1049564.TevJSym_bn00080	1.261e-102	345.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1J5P6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
EH2_k127_1722214_3	1286106.MPL1_09235	3.295e-132	429.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
EH2_k127_1722214_6	713586.KB900536_gene1694	3.753e-67	230.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_1722214_9	713586.KB900536_gene1693	8.123e-53	188.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_1722214_10	1123020.AUIE01000025_gene4780	1.259e-39	153.0	COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1YCQV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NT	Two component signalling adaptor domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
EH2_k127_1722214_0	396588.Tgr7_2901	6.231e-218	697.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales	135613|Chromatiales	NT	chemotaxis	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
EH2_k127_1730325_1	396588.Tgr7_3185	9.826e-225	711.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_1730325_3	765913.ThidrDRAFT_1704	7.181e-56	197.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales	135613|Chromatiales	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
EH2_k127_1730325_0	1049564.TevJSym_ai00870	7.861e-269	843.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1J4VK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
EH2_k127_1730325_2	330214.NIDE0805	3.001e-105	365.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
EH2_k127_1730325_4	1209072.ALBT01000061_gene983	9.659e-42	159.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,1FHHG@10|Cellvibrio	1236|Gammaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5638	Chor_lyase
EH2_k127_1730325_5	1198232.CYCME_1493	3.09e-36	138.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,460W4@72273|Thiotrichales	72273|Thiotrichales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH2_k127_1756658_0	314345.SPV1_09268	4.496e-59	211.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1756658_1	713586.KB900536_gene3024	8.677e-35	135.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ6P@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
EH2_k127_1780764_1	472759.Nhal_2676	7.329e-95	326.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales	135613|Chromatiales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
EH2_k127_1780764_0	713586.KB900536_gene123	1.198e-159	509.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
EH2_k127_1780764_3	1283300.ATXB01000001_gene2317	4.358e-50	196.0	COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1XG8Y@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1780764_2	981336.F944_02237	3.44e-69	237.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,3NIXJ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485	M20_dimer,Peptidase_M20
EH2_k127_1783410_5	472759.Nhal_1179	1.899e-21	94.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales	135613|Chromatiales	I	PFAM phosphoesterase PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
EH2_k127_1783410_1	153948.NAL212_2345	8.052e-158	509.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2W9B6@28216|Betaproteobacteria,372NE@32003|Nitrosomonadales	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
EH2_k127_1783410_4	686340.Metal_2129	1.52e-36	139.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,1TKPU@1236|Gammaproteobacteria,1XGHN@135618|Methylococcales	135618|Methylococcales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
EH2_k127_1783410_0	1027273.GZ77_14595	3.31e-202	635.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XIFG@135619|Oceanospirillales	135619|Oceanospirillales	E	in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_1783410_7	1336235.JAEG01000021_gene3386	6.769e-07	56.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TQPQ@28211|Alphaproteobacteria,4BBCE@82115|Rhizobiaceae	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH2_k127_1783410_3	1122134.KB893650_gene561	4.623e-63	227.0	2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria,1XMC6@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
EH2_k127_1783410_2	870187.Thini_0776	9.397e-71	244.0	COG2230@1|root,COG2230@2|Bacteria,1QVX6@1224|Proteobacteria,1T2MM@1236|Gammaproteobacteria,4628Q@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
EH2_k127_1811105_0	1123368.AUIS01000005_gene484	1.444e-122	402.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,2NC9T@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
EH2_k127_1811105_1	105559.Nwat_2604	4.408e-72	244.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WWEY@135613|Chromatiales	135613|Chromatiales	C	FAD linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
EH2_k127_1823030_0	768671.ThimaDRAFT_1655	2.592e-67	234.0	COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales	135613|Chromatiales	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
EH2_k127_1823030_1	1535422.ND16A_2335	4.928e-44	164.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,1S6DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
EH2_k127_185950_2	90813.JQMT01000001_gene260	1.388e-69	238.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH2_k127_185950_0	519989.ECTPHS_02394	8.974e-121	398.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1WXXP@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
EH2_k127_185950_1	391615.ABSJ01000022_gene272	9.633e-103	338.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1J4JE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
EH2_k127_1862928_0	396588.Tgr7_2004	1.076e-232	730.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales	135613|Chromatiales	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
EH2_k127_1907433_1	1209072.ALBT01000033_gene1616	9.361e-55	206.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1FGQB@10|Cellvibrio	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
EH2_k127_1907433_0	580332.Slit_0801	1.97e-111	375.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria,44WPB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,Sigma54_activat
EH2_k127_1912041_2	1122201.AUAZ01000020_gene2724	1.649e-70	244.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,466FV@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
EH2_k127_1912041_0	1117647.M5M_05205	2.423e-138	447.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1J7DI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
EH2_k127_1912041_1	1117647.M5M_05210	5.957e-124	400.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1J5QF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	2.6.1.104,2.6.1.59	ko:K02805,ko:K18653	-	-	R10698	RC00006,RC00781	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
EH2_k127_1912782_0	2340.JV46_20350	1.86e-130	422.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1J5UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
EH2_k127_1912782_1	1049564.TevJSym_ap00560	1.093e-08	59.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1J62R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
EH2_k127_1922357_0	323261.Noc_2001	1.538e-159	505.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales	135613|Chromatiales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
EH2_k127_1922357_2	1294143.H681_01955	4.704e-81	285.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	VPA0491	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
EH2_k127_1922357_1	85643.Tmz1t_0103	1.041e-110	366.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,2KVAT@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_1922357_3	1042377.AFPJ01000024_gene787	1.864e-63	222.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_4488	M20_dimer,Peptidase_M20,Peptidase_M28
EH2_k127_1933469_2	314345.SPV1_06124	5.613e-90	300.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria	1224|Proteobacteria	P	Urea carboxylase-associated protein 2	IV02_09290	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
EH2_k127_1933469_0	1120792.JAFV01000001_gene1790	3.129e-146	473.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_1933469_1	1430440.MGMSRv2_0114	9.593e-110	361.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,2JV48@204441|Rhodospirillales	204441|Rhodospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
EH2_k127_1933469_3	1281779.H009_00540	1.854e-40	156.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,2TT79@28211|Alphaproteobacteria,4B9EP@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
EH2_k127_1944935_0	742159.HMPREF0004_3253	7.69e-91	309.0	28ID9@1|root,2Z8FI@2|Bacteria,1PD20@1224|Proteobacteria,2VP91@28216|Betaproteobacteria,3T5I7@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1944935_1	296591.Bpro_3704	7.888e-52	187.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,2VUFT@28216|Betaproteobacteria,4AFA4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
EH2_k127_1944935_2	1096769.Pelub83DRAFT_0415	1.015e-21	96.0	2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1944935_3	243231.GSU0975	1.328e-11	65.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WM12@28221|Deltaproteobacteria,43W16@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
EH2_k127_1965689_2	42565.FP66_10700	0.0001803	47.0	COG1538@1|root,COG2885@1|root,COG1538@2|Bacteria,COG2885@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,1XIGH@135619|Oceanospirillales	135619|Oceanospirillales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,SPOR
EH2_k127_1965689_0	533240.CRC_01252	2.706e-22	112.0	COG0834@1|root,COG1404@1|root,COG1409@1|root,COG1520@1|root,COG2133@1|root,COG2931@1|root,COG3386@1|root,COG3537@1|root,COG5164@1|root,COG0834@2|Bacteria,COG1404@2|Bacteria,COG1409@2|Bacteria,COG1520@2|Bacteria,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG3537@2|Bacteria,COG5164@2|Bacteria,1G2N0@1117|Cyanobacteria,1HRSX@1161|Nostocales	1117|Cyanobacteria	GOQ	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF4347,HemolysinCabind,Laminin_G_3,SBP_bac_3,VCBS
EH2_k127_1965689_1	1198232.CYCME_0397	5.993e-18	87.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,1S90D@1236|Gammaproteobacteria,463M6@72273|Thiotrichales	72273|Thiotrichales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
EH2_k127_1975228_1	1122599.AUGR01000001_gene330	5.659e-09	65.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XI5V@135619|Oceanospirillales	135619|Oceanospirillales	S	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
EH2_k127_1975228_0	1165096.ARWF01000001_gene2209	1.704e-35	137.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,2KMHV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
EH2_k127_1981745_1	420662.Mpe_A1224	1.502e-40	162.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,2VZB4@28216|Betaproteobacteria,1KN0Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1981745_0	420662.Mpe_A1223	5.325e-54	195.0	2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,2W1BJ@28216|Betaproteobacteria,1KNAC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1981745_2	493475.GARC_2203	3.709e-36	140.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1985298_0	1278309.KB907101_gene665	1.537e-87	295.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1XM9N@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
EH2_k127_1985298_1	1535422.ND16A_3173	3.528e-43	165.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,2Q5MK@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1282
EH2_k127_1988599_0	395493.BegalDRAFT_1319	1.461e-164	535.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von willebrand factor, type A	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
EH2_k127_1988599_2	1123279.ATUS01000006_gene3359	1.948e-63	222.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
EH2_k127_1988599_1	396588.Tgr7_2294	1.994e-139	456.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
EH2_k127_2012305_1	1163617.SCD_n01356	4.473e-77	265.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
EH2_k127_2012305_2	1163617.SCD_n01355	1.561e-28	121.0	COG3090@1|root,COG3090@2|Bacteria,1PJMD@1224|Proteobacteria,2VYB1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
EH2_k127_2012305_0	1163617.SCD_n01354	1.694e-144	471.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
EH2_k127_2012305_3	713586.KB900536_gene1252	3.901e-15	83.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria	1224|Proteobacteria	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_203186_0	870187.Thini_2905	1.658e-175	555.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,460AS@72273|Thiotrichales	72273|Thiotrichales	C	radical SAM protein YgiQ	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
EH2_k127_2042163_0	1163617.SCD_n02228	1.981e-286	885.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
EH2_k127_2059503_1	1134474.O59_001449	4.934e-81	278.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1FH4D@10|Cellvibrio	1236|Gammaproteobacteria	J	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
EH2_k127_2059503_0	62928.azo2354	7.585e-174	550.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,2KUSU@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0798 Arsenite efflux pump ACR3 and related permeases	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
EH2_k127_2059503_3	1249627.D779_2581	3.955e-61	213.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S46G@1236|Gammaproteobacteria,1WY8P@135613|Chromatiales	135613|Chromatiales	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
EH2_k127_2059503_2	1123393.KB891329_gene942	9.231e-63	222.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2WABD@28216|Betaproteobacteria,1KRZU@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH2_k127_2059503_5	1123393.KB891329_gene941	6.851e-43	158.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,1KT8S@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
EH2_k127_2059503_4	85643.Tmz1t_3958	9.698e-48	175.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VN6W@28216|Betaproteobacteria,2KVGJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
EH2_k127_2061751_2	396588.Tgr7_2901	4.536e-47	172.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales	135613|Chromatiales	NT	chemotaxis	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
EH2_k127_2061751_0	83406.HDN1F_36800	0.0	1142.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1J4QC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH2_k127_2061751_3	225937.HP15_3520	1.342e-20	97.0	COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis signal transduction protein	chpC	-	-	ko:K06598	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_2061751_1	1122603.ATVI01000012_gene1200	1.982e-64	228.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
EH2_k127_206914_4	2340.JV46_22530	5.661e-106	349.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,1JBNA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
EH2_k127_206914_0	1123514.KB905899_gene842	0.0	1122.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_206914_3	2340.JV46_22500	1.889e-126	409.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_206914_5	393305.YE1167	2.557e-65	226.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,41DB6@629|Yersinia	1236|Gammaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
EH2_k127_206914_2	1469607.KK073769_gene5541	4.905e-131	425.0	COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1HJTM@1161|Nostocales	1117|Cyanobacteria	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	ddh	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH2_k127_206914_6	330214.NIDE1696	8.026e-43	166.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
EH2_k127_206914_1	883126.HMPREF9710_03437	3.942e-145	466.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria,473X7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
EH2_k127_206914_7	745411.B3C1_13698	2.166e-42	159.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1J7BB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
EH2_k127_206914_8	926554.KI912633_gene4039	2.605e-11	66.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
EH2_k127_208393_0	396588.Tgr7_2744	5.884e-104	349.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
EH2_k127_208393_1	1158165.KB898871_gene2402	1.27e-46	170.0	COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,1SJ46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
EH2_k127_208393_3	667121.ET1_26_00180	8.721e-11	70.0	COG3266@1|root,COG3266@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division protein DamX	damX	GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
EH2_k127_208393_2	870187.Thini_0225	9.049e-32	126.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
EH2_k127_2088219_2	747365.Thena_1007	1.162e-43	168.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	fkpB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Methyltransf_11
EH2_k127_2088219_0	686340.Metal_2963	1.03e-84	291.0	COG3272@1|root,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XEGF@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
EH2_k127_2088219_1	395493.BegalDRAFT_1819	6.16e-68	241.0	COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S78T@1236|Gammaproteobacteria,463IS@72273|Thiotrichales	72273|Thiotrichales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
EH2_k127_2088219_3	765910.MARPU_11930	1.408e-14	74.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales	135613|Chromatiales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
EH2_k127_2108618_1	234831.PSM_A2425	1.383e-31	134.0	COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,2Q286@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
EH2_k127_2108618_0	34007.IT40_22050	2.676e-200	634.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,2U2WN@28211|Alphaproteobacteria,2PY57@265|Paracoccus	28211|Alphaproteobacteria	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
EH2_k127_2108618_2	1280953.HOC_19491	6.772e-06	52.0	COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,2U1TZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
EH2_k127_2122831_1	1449063.JMLS01000025_gene3959	8.002e-96	318.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4HAVS@91061|Bacilli,26R6G@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_2122831_2	519989.ECTPHS_00510	2.117e-70	245.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1WX0F@135613|Chromatiales	135613|Chromatiales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
EH2_k127_2122831_3	1336233.JAEH01000008_gene2254	3.06e-67	234.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,2Q9GY@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH2_k127_2122831_4	1123355.JHYO01000001_gene3180	7.669e-33	139.0	COG5607@1|root,COG5607@2|Bacteria,1QTX6@1224|Proteobacteria,2TWMZ@28211|Alphaproteobacteria,371HE@31993|Methylocystaceae	28211|Alphaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
EH2_k127_2122831_0	396588.Tgr7_1280	1.576e-134	454.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria	1224|Proteobacteria	L	double-strand break repair protein AddB	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
EH2_k127_2163591_0	472759.Nhal_3052	4.262e-87	297.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1WW69@135613|Chromatiales	135613|Chromatiales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
EH2_k127_2163591_6	1158146.KB907134_gene1475	1.993e-12	73.0	COG0680@1|root,COG0680@2|Bacteria,1RGFM@1224|Proteobacteria,1S4XN@1236|Gammaproteobacteria,1WY9T@135613|Chromatiales	135613|Chromatiales	C	PFAM Peptidase A31, hydrogen uptake protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
EH2_k127_2163591_1	713586.KB900536_gene1719	4.189e-62	217.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH2_k127_2163591_5	391615.ABSJ01000050_gene1167	6.939e-15	84.0	2ESKN@1|root,33K58@2|Bacteria,1NAWS@1224|Proteobacteria,1SIFP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type II secretion system (T2SS), protein N	-	-	-	-	-	-	-	-	-	-	-	-	T2SSN
EH2_k127_2163591_4	396588.Tgr7_0237	2.994e-18	91.0	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,1WZQA@135613|Chromatiales	135613|Chromatiales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
EH2_k127_2163591_2	1122603.ATVI01000005_gene3707	9.431e-36	151.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1X6HI@135614|Xanthomonadales	135614|Xanthomonadales	U	GspL periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	GspL_C,T2SSL
EH2_k127_2163591_3	1033802.SSPSH_003285	8.907e-29	124.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway component PulK	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
EH2_k127_2166901_3	1033802.SSPSH_000385	3.235e-75	258.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
EH2_k127_2166901_2	1121920.AUAU01000010_gene117	5.222e-78	265.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	MA20_15105	-	-	-	-	-	-	-	-	-	-	-	AHSA1
EH2_k127_2166901_6	396588.Tgr7_2593	2.783e-06	56.0	2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH2_k127_2166901_4	1236542.BALM01000008_gene2921	5.362e-28	120.0	2BX6S@1|root,324B7@2|Bacteria,1RJA2@1224|Proteobacteria,1SCPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1439
EH2_k127_2166901_5	1198232.CYCME_0241	3.1e-08	57.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,46151@72273|Thiotrichales	72273|Thiotrichales	H	PFAM UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH2_k127_2166901_0	1121935.AQXX01000120_gene4912	4.539e-123	402.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1XI81@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
EH2_k127_2166901_1	1120963.KB894497_gene2235	3.608e-121	397.0	COG1776@1|root,COG4753@1|root,COG1776@2|Bacteria,COG4753@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,2PZSU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG0784 FOG CheY-like receiver	cheC	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_2172499_0	338963.Pcar_2072	5.88e-211	673.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,43U9J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	THUMP	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
EH2_k127_2172499_2	1049564.TevJSym_ac01570	1.253e-27	118.0	COG3160@1|root,COG3160@2|Bacteria	2|Bacteria	K	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase	rsd	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	ko:K07740	-	-	-	-	ko00000	-	-	-	Rsd_AlgQ
EH2_k127_2172499_1	111781.Lepto7376_0423	5.87e-104	341.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1H72I@1150|Oscillatoriales	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
EH2_k127_2174098_5	765914.ThisiDRAFT_1008	3.161e-47	173.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales	135613|Chromatiales	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
EH2_k127_2174098_0	2340.JV46_04770	1.841e-237	758.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1J4XZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
EH2_k127_2174098_10	2340.JV46_19880	3.694e-12	73.0	COG3218@1|root,COG3218@2|Bacteria,1N13E@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
EH2_k127_2174098_6	1244869.H261_16972	1.338e-44	173.0	COG1463@1|root,COG1463@2|Bacteria,1RCV1@1224|Proteobacteria,2U6E9@28211|Alphaproteobacteria,2JRVS@204441|Rhodospirillales	204441|Rhodospirillales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH2_k127_2174098_2	2340.JV46_19850	5.922e-111	364.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RQVA@1236|Gammaproteobacteria,1J964@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC transporter	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH2_k127_2174098_4	2340.JV46_19840	7.85e-80	274.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1SKTY@1236|Gammaproteobacteria,1JA8F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
EH2_k127_2174098_7	1049564.TevJSym_ac01830	3.097e-31	125.0	COG1366@1|root,COG1366@2|Bacteria,1N6U1@1224|Proteobacteria,1SJ1P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Anti-sigma-factor antagonist	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
EH2_k127_2174098_8	1430440.MGMSRv2_1736	1.845e-25	111.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBR@1224|Proteobacteria,2U1RE@28211|Alphaproteobacteria,2JZB7@204441|Rhodospirillales	204441|Rhodospirillales	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,SpoIIE
EH2_k127_2174098_1	1049564.TevJSym_ac01850	1.251e-119	405.0	COG1639@1|root,COG2208@1|root,COG1639@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1JA7R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	GAF,GAF_2,HATPase_c_2,PAS,SpoIIE
EH2_k127_2174098_3	396588.Tgr7_2425	2.104e-82	284.0	COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,1WY0K@135613|Chromatiales	135613|Chromatiales	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
EH2_k127_2175422_0	1269813.ATUL01000019_gene310	0.0	1183.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
EH2_k127_2175422_5	1123401.JHYQ01000035_gene3488	1.687e-42	157.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,1S9CV@1236|Gammaproteobacteria,462VV@72273|Thiotrichales	72273|Thiotrichales	P	TIGRFAM nitrite reductase NAD(P)H , small subunit	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
EH2_k127_2175422_7	870187.Thini_2588	3.713e-30	122.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_2175422_2	1121374.KB891582_gene1730	3.975e-45	170.0	COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
EH2_k127_2175422_8	1226994.AMZB01000136_gene5080	1.198e-19	92.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria,1YGPU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
EH2_k127_2175422_3	357804.Ping_1764	8.541e-45	173.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2175422_6	1049564.TevJSym_ad00410	1.245e-39	151.0	2E8HY@1|root,332W0@2|Bacteria,1N9SS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2175422_4	237368.SCABRO_03545	9.653e-43	160.0	COG2138@1|root,COG2138@2|Bacteria,2J082@203682|Planctomycetes	203682|Planctomycetes	H	Cobalamin (Vitamin B12) biosynthesis CbiX protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
EH2_k127_2175422_1	1163407.UU7_12009	4.688e-128	423.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
EH2_k127_2212359_2	1134474.O59_000466	2.228e-32	143.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2212359_3	1122604.JONR01000007_gene2935	1.354e-29	135.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
EH2_k127_2212359_1	1122604.JONR01000007_gene2936	3.314e-95	324.0	28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2212359_4	1117647.M5M_07310	9.142e-27	110.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,1J74D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA-binding protein VF530	-	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	VF530
EH2_k127_2212359_0	391615.ABSJ01000042_gene2274	5.5e-167	538.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
EH2_k127_2235319_1	472759.Nhal_2338	7.615e-28	117.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1WWH5@135613|Chromatiales	135613|Chromatiales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
EH2_k127_2235319_0	765914.ThisiDRAFT_2568	8.868e-34	134.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1WYGU@135613|Chromatiales	135613|Chromatiales	N	flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
EH2_k127_225344_3	1049564.TevJSym_at00710	9.94e-33	133.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1J5UE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
EH2_k127_225344_1	1286106.MPL1_06642	9.846e-57	205.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales	72273|Thiotrichales	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH2_k127_225344_2	626887.J057_09916	8.644e-54	196.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,466ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	dsbA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
EH2_k127_225344_0	1294143.H681_01065	2.069e-79	289.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	pleD	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH2_k127_2256051_10	396588.Tgr7_1216	7.58e-20	90.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WW26@135613|Chromatiales	135613|Chromatiales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH2_k127_2256051_9	243924.LT42_09045	8.074e-43	160.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH2_k127_2256051_3	1117647.M5M_02195	1.579e-112	371.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1J4FK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
EH2_k127_2256051_6	1123368.AUIS01000001_gene1995	2.604e-68	249.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SQ5V@1236|Gammaproteobacteria,2ND8R@225057|Acidithiobacillales	225057|Acidithiobacillales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal
EH2_k127_2256051_8	519989.ECTPHS_05671	4.631e-44	169.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1WY0I@135613|Chromatiales	135613|Chromatiales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
EH2_k127_2256051_13	349124.Hhal_0524	1.051e-07	57.0	COG2747@1|root,COG2747@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
EH2_k127_2256051_7	1304883.KI912532_gene2484	2.113e-50	187.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,2KW9J@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
EH2_k127_2256051_2	1122951.ATUE01000007_gene769	1.112e-113	373.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,3NJHP@468|Moraxellaceae	1236|Gammaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
EH2_k127_2256051_5	319224.Sputcn32_1159	3.616e-72	250.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,2QAXH@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
EH2_k127_2256051_12	754476.Q7A_1378	6.978e-13	73.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,461I7@72273|Thiotrichales	72273|Thiotrichales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845,N_methyl
EH2_k127_2256051_4	1116472.MGMO_60c00260	4.943e-96	321.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XEDU@135618|Methylococcales	135618|Methylococcales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
EH2_k127_2256051_0	391615.ABSJ01000002_gene479	5.746e-294	911.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1J4DD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
EH2_k127_2256051_11	748247.AZKH_2839	1.393e-13	74.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KXAK@206389|Rhodocyclales	206389|Rhodocyclales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
EH2_k127_2256051_1	472759.Nhal_0717	4.089e-156	506.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
EH2_k127_2272129_10	1049564.TevJSym_ag01040	1.204e-48	179.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1J4V0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
EH2_k127_2272129_2	477228.YO5_20082	3.175e-129	425.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1Z0WQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
EH2_k127_2272129_0	713586.KB900536_gene2224	1.8e-196	622.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales	135613|Chromatiales	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
EH2_k127_2272129_1	396588.Tgr7_0202	3.821e-182	581.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales	135613|Chromatiales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH2_k127_2272129_8	1158760.AQXP01000048_gene1152	2.724e-71	252.0	COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1X2ER@135613|Chromatiales	135613|Chromatiales	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.243	ko:K02560	ko00540,ko01100,map00540,map01100	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
EH2_k127_2272129_3	1288494.EBAPG3_27890	6.35e-129	423.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
EH2_k127_2272129_6	1123392.AQWL01000003_gene424	2.071e-92	317.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,1KT30@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_2272129_5	754476.Q7A_1581	1.433e-101	338.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,460H0@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
EH2_k127_2272129_9	351348.Maqu_2791	6.332e-67	233.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG3038 Cytochrome B561	yceJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
EH2_k127_2272129_7	740709.A10D4_11581	1.633e-72	249.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,2QF1C@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
EH2_k127_2272129_4	396588.Tgr7_0288	6.249e-107	352.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1X02D@135613|Chromatiales	135613|Chromatiales	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
EH2_k127_2284540_1	1408444.JHYC01000004_gene674	1.186e-28	121.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1JEF5@118969|Legionellales	118969|Legionellales	L	DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
EH2_k127_2284540_0	472759.Nhal_2070	3.494e-101	331.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH2_k127_2297533_1	1123368.AUIS01000003_gene1810	6.669e-56	203.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS-domain-containing membrane protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	HPP
EH2_k127_2297533_0	1122134.KB893650_gene1012	8.045e-97	321.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XHX2@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH2_k127_2297533_2	1150621.SMUL_3065	1.29e-09	59.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger
EH2_k127_2327810_2	2340.JV46_14680	5.299e-143	457.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1J4FM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0066	HMGL-like,LeuA_dimer
EH2_k127_2327810_4	314278.NB231_15338	1.226e-94	316.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1WWDZ@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
EH2_k127_2327810_1	398767.Glov_2501	1.617e-189	595.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
EH2_k127_2327810_5	1123392.AQWL01000001_gene1476	4.282e-67	231.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KRJT@119069|Hydrogenophilales	119069|Hydrogenophilales	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
EH2_k127_2327810_0	396588.Tgr7_2158	1.06e-291	904.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH2_k127_2327810_3	580332.Slit_1670	2.533e-98	330.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,2W0RY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2327810_6	876044.IMCC3088_2090	4.291e-33	132.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
EH2_k127_2328644_1	1298593.TOL_2499	3.821e-50	181.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XHYT@135619|Oceanospirillales	135619|Oceanospirillales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
EH2_k127_2328644_2	83406.HDN1F_14700	1.113e-45	168.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1J695@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C,FliN_N
EH2_k127_2328644_3	1049564.TevJSym_aw00560	1.071e-17	88.0	COG3190@1|root,COG3190@2|Bacteria,1QJ8N@1224|Proteobacteria,1TH71@1236|Gammaproteobacteria,1JAA7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar biosynthesis protein, FliO	-	-	-	-	-	-	-	-	-	-	-	-	FliO
EH2_k127_2328644_0	1026882.MAMP_00962	4.524e-89	300.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,46081@72273|Thiotrichales	72273|Thiotrichales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
EH2_k127_2328644_4	1216976.AX27061_5930	6.627e-14	71.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,3T20E@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
EH2_k127_233393_0	292415.Tbd_2509	6.055e-153	488.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,1KRZS@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
EH2_k127_233393_1	398767.Glov_1986	7.042e-121	395.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_233393_2	398767.Glov_1987	4.909e-63	225.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
EH2_k127_237884_5	857087.Metme_2350	3.542e-36	142.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1XE2F@135618|Methylococcales	135618|Methylococcales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
EH2_k127_237884_2	631362.Thi970DRAFT_03518	1.493e-57	207.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1WXQD@135613|Chromatiales	135613|Chromatiales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
EH2_k127_237884_1	1163617.SCD_n00905	1.683e-95	323.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_237884_0	1123368.AUIS01000018_gene719	2.954e-152	514.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RRFG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_2
EH2_k127_237884_4	1278309.KB907101_gene381	1.095e-55	212.0	COG0457@1|root,COG0457@2|Bacteria,1R9GZ@1224|Proteobacteria,1RZID@1236|Gammaproteobacteria,1XKTX@135619|Oceanospirillales	135619|Oceanospirillales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
EH2_k127_237884_3	391615.ABSJ01000042_gene2194	1.608e-56	211.0	COG4254@1|root,COG4254@2|Bacteria,1RJR0@1224|Proteobacteria,1S8WR@1236|Gammaproteobacteria,1JBNT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
EH2_k127_2417853_0	870187.Thini_4176	9.562e-175	557.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,45ZS9@72273|Thiotrichales	72273|Thiotrichales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH2_k127_2418689_0	396588.Tgr7_0483	1.294e-99	341.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales	135613|Chromatiales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
EH2_k127_2423478_2	713586.KB900536_gene1770	1.173e-49	181.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales	135613|Chromatiales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH2_k127_2423478_0	1123255.JHYS01000004_gene966	4.088e-109	357.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,2VRHY@28216|Betaproteobacteria,4AFE9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
EH2_k127_2423478_1	296591.Bpro_0212	1.507e-58	223.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1NC9X@1224|Proteobacteria,2WHF9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
EH2_k127_2423478_3	395493.BegalDRAFT_0922	1.89e-47	172.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,460V9@72273|Thiotrichales	72273|Thiotrichales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
EH2_k127_2425728_2	1288826.MSNKSG1_12272	3.248e-15	81.0	COG4585@1|root,COG4585@2|Bacteria,1QSUV@1224|Proteobacteria,1RR41@1236|Gammaproteobacteria,469GB@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG4585 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
EH2_k127_2425728_1	930169.B5T_00849	8.997e-60	214.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,1S3QG@1236|Gammaproteobacteria,1XNWZ@135619|Oceanospirillales	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH2_k127_2425728_0	713587.THITH_01340	4.914e-155	495.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
EH2_k127_2425728_3	373903.Hore_17680	1.825e-08	62.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,24F0X@186801|Clostridia,3WAA6@53433|Halanaerobiales	186801|Clostridia	M	PFAM Surface antigen variable number repeat	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH2_k127_2426209_0	1517416.IDAT_11075	3.746e-183	576.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,2QF9G@267893|Idiomarinaceae	1236|Gammaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
EH2_k127_2448935_0	261292.Nit79A3_0793	5.287e-122	394.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,371UB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
EH2_k127_2448935_1	1163617.SCD_n00048	8.344e-44	168.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2457366_4	1001585.MDS_0701	8.226e-05	45.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,1S8A4@1236|Gammaproteobacteria,1YHBW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2457366_1	1163617.SCD_n01616	2.794e-88	313.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_2457366_3	1163617.SCD_n02832	7.684e-05	52.0	2EKS4@1|root,33EFW@2|Bacteria,1NNJB@1224|Proteobacteria,2VYYD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
EH2_k127_2457366_0	472759.Nhal_2695	2.807e-320	992.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1WW8W@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
EH2_k127_2457366_2	153948.NAL212_1418	8.931e-07	52.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,2VS72@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
EH2_k127_2458320_3	888048.HMPREF8577_1502	3.574e-15	80.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
EH2_k127_2458320_1	396588.Tgr7_0002	4.619e-140	454.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1WWQF@135613|Chromatiales	135613|Chromatiales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
EH2_k127_2458320_0	519989.ECTPHS_07601	2.552e-211	665.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
EH2_k127_2458320_2	1266998.ATUJ01000016_gene960	4.077e-16	78.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,2PXT4@265|Paracoccus	28211|Alphaproteobacteria	J	In Escherichia coli transcription of this gene is enhanced by polyamines	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
EH2_k127_2464735_4	765910.MARPU_15670	5.734e-35	138.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales	135613|Chromatiales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH2_k127_2464735_2	519989.ECTPHS_09333	1.029e-66	235.0	COG0535@1|root,COG0535@2|Bacteria,1QUQ6@1224|Proteobacteria,1T20T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
EH2_k127_2464735_6	311403.Arad_0812	6.173e-13	79.0	COG0790@1|root,COG1196@1|root,COG3170@1|root,COG3409@1|root,COG0790@2|Bacteria,COG1196@2|Bacteria,COG3170@2|Bacteria,COG3409@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4B8SF@82115|Rhizobiaceae	28211|Alphaproteobacteria	DM	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	PG_binding_1,Sel1
EH2_k127_2464735_1	765911.Thivi_4572	3.445e-227	707.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
EH2_k127_2464735_3	765912.Thimo_2093	3.182e-39	148.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales	135613|Chromatiales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
EH2_k127_2464735_0	697282.Mettu_0640	1.401e-259	811.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XEC1@135618|Methylococcales	135618|Methylococcales	O	ATP-dependent Clp protease, ATP-binding subunit ClpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_2468210_1	472759.Nhal_1157	6.092e-181	570.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH2_k127_2468210_2	765912.Thimo_3615	2.688e-54	195.0	COG0071@1|root,COG0071@2|Bacteria,1RH6E@1224|Proteobacteria,1S6FC@1236|Gammaproteobacteria,1WYSM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
EH2_k127_2468210_0	1163617.SCD_n01151	2.984e-209	659.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
EH2_k127_2490357_3	1121921.KB898709_gene139	2.562e-22	97.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,2PMMG@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	RsgA GTPase	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase
EH2_k127_2490357_2	232346.JHQL01000003_gene227	7.008e-44	166.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XHIQ@135619|Oceanospirillales	135619|Oceanospirillales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
EH2_k127_2490357_4	1026882.MAMP_01656	2.456e-10	66.0	COG2010@1|root,COG2010@2|Bacteria,1QMV6@1224|Proteobacteria,1SHJ3@1236|Gammaproteobacteria,463DX@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2490357_0	1123399.AQVE01000001_gene559	4.932e-164	526.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
EH2_k127_2490357_1	1245471.PCA10_51890	1.892e-81	281.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1YE7U@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
EH2_k127_2504677_3	1041159.AZUW01000014_gene960	6.195e-62	218.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
EH2_k127_2504677_1	420324.KI911970_gene1565	1.6e-137	445.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,1JXGQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
EH2_k127_2504677_2	1283300.ATXB01000001_gene390	7.12e-85	291.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
EH2_k127_2504677_0	1232410.KI421426_gene1474	2.288e-147	477.0	COG3264@1|root,COG3264@2|Bacteria,1QUDC@1224|Proteobacteria,43DHA@68525|delta/epsilon subdivisions,2X8P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH2_k127_2532565_1	95619.PM1_0201865	2.803e-212	668.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_2532565_2	396588.Tgr7_3261	4.218e-122	402.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
EH2_k127_2532565_0	754476.Q7A_1290	1.953e-243	760.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
EH2_k127_2532565_3	765914.ThisiDRAFT_2284	1.621e-25	109.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
EH2_k127_2539219_1	1163617.SCD_n00300	1.187e-71	245.0	2DS8H@1|root,32USH@2|Bacteria,1RCDN@1224|Proteobacteria,2W06A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
EH2_k127_2539219_0	614083.AWQR01000005_gene1152	4.335e-110	363.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,2VI48@28216|Betaproteobacteria,4AD28@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Ion transport protein	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
EH2_k127_2539219_2	1121374.KB891585_gene2169	1.912e-07	55.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
EH2_k127_2553153_0	2340.JV46_14790	2.521e-134	433.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1J5D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360	ACP_syn_III,ACP_syn_III_C
EH2_k127_2553153_1	713586.KB900536_gene790	7.193e-55	194.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
EH2_k127_2559423_0	580332.Slit_0303	5.372e-84	280.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
EH2_k127_2559423_1	1049564.TevJSym_bd00250	1.573e-73	252.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
EH2_k127_2560317_2	891974.E05_43450	5.079e-87	294.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,283CV@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	S	Ribosomal RNA large subunit methyltransferase D, RlmJ	rlmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
EH2_k127_2560317_5	396588.Tgr7_0591	5.865e-41	154.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales	135613|Chromatiales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
EH2_k127_2560317_3	519989.ECTPHS_09173	1.104e-84	286.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1WYMH@135613|Chromatiales	135613|Chromatiales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
EH2_k127_2560317_1	1278309.KB907100_gene2344	3.082e-137	440.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XHJU@135619|Oceanospirillales	135619|Oceanospirillales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
EH2_k127_2560317_0	1121935.AQXX01000112_gene5702	1.905e-215	682.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales	135619|Oceanospirillales	P	Phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH2_k127_2560317_4	395493.BegalDRAFT_0871	4.545e-52	185.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,460B9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH2_k127_256547_1	1499967.BAYZ01000116_gene3146	4.403e-22	100.0	2EEHS@1|root,338BM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_256547_0	519989.ECTPHS_07331	0.0	1142.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
EH2_k127_2577537_4	1229485.AMYV01000022_gene139	4.608e-21	98.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1JAG3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
EH2_k127_2577537_0	396588.Tgr7_2132	1.081e-145	472.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1WVYA@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
EH2_k127_2577537_2	713586.KB900536_gene951	1.734e-57	204.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1WY0J@135613|Chromatiales	135613|Chromatiales	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
EH2_k127_2577537_3	1123401.JHYQ01000007_gene533	4.169e-51	188.0	COG0303@1|root,COG0746@1|root,COG1763@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales	72273|Thiotrichales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MobB,MoeA_C,MoeA_N,NTP_transf_3
EH2_k127_2577537_1	472759.Nhal_0930	2.13e-106	357.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH2_k127_2584831_0	1121935.AQXX01000144_gene4527	2.519e-200	632.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1XHAB@135619|Oceanospirillales	135619|Oceanospirillales	K	accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
EH2_k127_2584831_1	396588.Tgr7_3149	2.288e-71	255.0	COG2199@1|root,COG3706@2|Bacteria,1R59V@1224|Proteobacteria,1S4YK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
EH2_k127_2584831_2	1123502.AQXD01000001_gene597	2.815e-16	78.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1X53V@135614|Xanthomonadales	135614|Xanthomonadales	T	gtp-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
EH2_k127_2585141_0	1049564.TevJSym_aw00130	1.593e-254	792.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
EH2_k127_2585141_1	1049564.TevJSym_aw00140	3.67e-16	78.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,1RYZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
EH2_k127_2602559_7	177439.DP0078	0.0002845	44.0	COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,42TZC@68525|delta/epsilon subdivisions,2WQAM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2058)	-	-	-	ko:K09912	-	-	-	-	ko00000	-	-	-	DUF2058
EH2_k127_2602559_1	204773.HEAR2934	7.862e-116	387.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VK6G@28216|Betaproteobacteria,478WM@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
EH2_k127_2602559_6	404589.Anae109_2950	2.473e-24	108.0	COG0517@1|root,COG0517@2|Bacteria,1QXTZ@1224|Proteobacteria,43C6G@68525|delta/epsilon subdivisions,2X7GP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_2602559_4	1295642.H839_01966	3.533e-27	115.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4HHZP@91061|Bacilli,1WGA6@129337|Geobacillus	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_2602559_5	1112217.PPL19_21646	2.989e-25	109.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
EH2_k127_2602559_2	765914.ThisiDRAFT_0986	3.287e-61	213.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
EH2_k127_2602559_0	314345.SPV1_13604	2.15e-251	795.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria	1224|Proteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	iSFV_1184.SFV_2673	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_2602559_3	666681.M301_0260	1.036e-58	212.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,2KNPR@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
EH2_k127_2612645_2	1049564.TevJSym_aa01700	1.293e-67	237.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1J4T9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2925 Exonuclease I	sbcB	GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
EH2_k127_2612645_4	1168059.KB899087_gene1061	3.82e-07	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
EH2_k127_2612645_1	261292.Nit79A3_0382	2.48e-78	267.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,371MU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
EH2_k127_2612645_3	572477.Alvin_1238	6.589e-08	58.0	2E6PA@1|root,3319P@2|Bacteria,1NCA7@1224|Proteobacteria,1SEDT@1236|Gammaproteobacteria,1WZ90@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2612645_0	697282.Mettu_4090	7.437e-119	394.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,1XEPN@135618|Methylococcales	135618|Methylococcales	E	PFAM Glycosyl transferase, family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH2_k127_2620175_0	870187.Thini_3048	2.431e-135	439.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,45ZWG@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,HemN_C,Radical_SAM
EH2_k127_2623368_3	317025.Tcr_0280	1.121e-52	190.0	COG3193@1|root,COG3193@2|Bacteria,1RK4B@1224|Proteobacteria,1S256@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
EH2_k127_2623368_2	261292.Nit79A3_2171	2.02e-58	213.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,37331@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
EH2_k127_2623368_1	395493.BegalDRAFT_0993	2.035e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,460T8@72273|Thiotrichales	72273|Thiotrichales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
EH2_k127_2623368_0	870187.Thini_0101	1.22e-159	505.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
EH2_k127_2626006_0	870187.Thini_1278	4.248e-103	347.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,46024@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH2_k127_2626006_1	1123399.AQVE01000015_gene1813	3.014e-65	229.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH2_k127_2637304_0	948565.AFFP02000001_gene797	5.804e-105	343.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1Y86A@135625|Pasteurellales	135625|Pasteurellales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
EH2_k127_2637304_1	1123517.JOMR01000001_gene852	1.069e-46	171.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,460PY@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
EH2_k127_2661510_0	1255043.TVNIR_2729	1.073e-74	253.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1WX1J@135613|Chromatiales	135613|Chromatiales	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH2_k127_2661510_2	1198232.CYCME_1660	9.66e-24	104.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
EH2_k127_2661510_3	572477.Alvin_0244	2.141e-08	57.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales	135613|Chromatiales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
EH2_k127_2661510_1	1033802.SSPSH_001604	1.92e-32	135.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
EH2_k127_2676328_3	582744.Msip34_0505	1.81e-11	67.0	2BWYA@1|root,32WXT@2|Bacteria,1N26T@1224|Proteobacteria,2VXGX@28216|Betaproteobacteria,2KNZC@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2676328_0	713586.KB900536_gene1360	5.515e-66	233.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales	135613|Chromatiales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
EH2_k127_2676328_1	472759.Nhal_3850	1.263e-53	195.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1WY99@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
EH2_k127_2676328_2	713587.THITH_14395	1.8e-15	76.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1WW7R@135613|Chromatiales	135613|Chromatiales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
EH2_k127_2685511_1	1167006.UWK_02661	6.645e-65	233.0	COG3391@1|root,COG3391@2|Bacteria,1NZ87@1224|Proteobacteria	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2685511_0	1304885.AUEY01000011_gene1728	2.865e-95	328.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QYY@68525|delta/epsilon subdivisions,2WNXG@28221|Deltaproteobacteria,2MNAV@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
EH2_k127_2690311_8	1123517.JOMR01000001_gene1864	7.941e-24	101.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,4617P@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
EH2_k127_2690311_7	857087.Metme_3797	3.516e-53	190.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XF8B@135618|Methylococcales	135618|Methylococcales	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
EH2_k127_2690311_1	396588.Tgr7_2304	1.82e-211	664.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
EH2_k127_2690311_9	519989.ECTPHS_13163	6.419e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,1WZNA@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
EH2_k127_2690311_6	1196835.A458_17980	2.636e-54	192.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1Z30N@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
EH2_k127_2690311_4	765914.ThisiDRAFT_1666	2.565e-67	230.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1WYDZ@135613|Chromatiales	135613|Chromatiales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
EH2_k127_2690311_3	765914.ThisiDRAFT_1665	1.159e-97	322.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
EH2_k127_2690311_2	1279017.AQYJ01000019_gene1472	7.706e-150	480.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,464HA@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
EH2_k127_2690311_5	1036674.A28LD_0219	3.172e-55	195.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,2QG0Y@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
EH2_k127_2690311_0	717773.Thicy_0156	3.337e-251	781.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
EH2_k127_2698302_6	1123399.AQVE01000002_gene2319	5.392e-58	205.0	COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_2698302_3	1390370.O203_17850	9.492e-81	279.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1YD5T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_2698302_8	631362.Thi970DRAFT_02034	7.834e-46	179.0	COG0607@1|root,COG2905@1|root,COG0607@2|Bacteria,COG2905@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1WWD6@135613|Chromatiales	135613|Chromatiales	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
EH2_k127_2698302_11	857087.Metme_3182	1.293e-14	77.0	2AUTZ@1|root,31KH1@2|Bacteria,1QIC9@1224|Proteobacteria,1TG6N@1236|Gammaproteobacteria,1XFT8@135618|Methylococcales	135618|Methylococcales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
EH2_k127_2698302_9	85643.Tmz1t_2219	3.775e-30	126.0	COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,2VTY6@28216|Betaproteobacteria,2KWWH@206389|Rhodocyclales	206389|Rhodocyclales	M	SprA-related family	-	-	-	-	-	-	-	-	-	-	-	-	SprA-related
EH2_k127_2698302_12	765910.MARPU_03950	1.991e-10	64.0	2ECYK@1|root,336VN@2|Bacteria,1NCGJ@1224|Proteobacteria,1SFQM@1236|Gammaproteobacteria,1WZH5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2698302_4	391615.ABSJ01000030_gene807	2.425e-72	250.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1J5NC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
EH2_k127_2698302_1	396588.Tgr7_2013	5.088e-110	363.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1WW4R@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
EH2_k127_2698302_0	396588.Tgr7_2014	5.208e-228	710.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
EH2_k127_2698302_5	765912.Thimo_0972	3.884e-70	244.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1WWRR@135613|Chromatiales	135613|Chromatiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
EH2_k127_2698302_2	395493.BegalDRAFT_2360	6.732e-90	300.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,460FH@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
EH2_k127_2698302_7	105559.Nwat_2231	1.556e-57	207.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1WX92@135613|Chromatiales	135613|Chromatiales	D	probably involved in intracellular septation	-	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
EH2_k127_2698302_10	1479235.KK366039_gene2953	1.043e-17	85.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XKEK@135619|Oceanospirillales	135619|Oceanospirillales	S	YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
EH2_k127_2710650_1	375286.mma_2596	2.239e-83	279.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
EH2_k127_2710650_2	519989.ECTPHS_02621	3.167e-76	265.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems permease components	znuB	GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iEC042_1314.EC042_2026,iECABU_c1320.ECABU_c21210,iECED1_1282.ECED1_2064,iECNA114_1301.ECNA114_1921,iECSF_1327.ECSF_1717,iECUMN_1333.ECUMN_2157,iEcSMS35_1347.EcSMS35_1327,iG2583_1286.G2583_2311,iSSON_1240.SSON_1282,iYL1228.KPN_02374,ic_1306.c2273	ABC-3
EH2_k127_2710650_0	519989.ECTPHS_02626	1.067e-90	307.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1WXP4@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
EH2_k127_2710650_3	349124.Hhal_1730	2.862e-52	196.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
EH2_k127_2718137_0	1049564.TevJSym_aj00010	9.661e-27	123.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1JA89@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
EH2_k127_2725280_1	395493.BegalDRAFT_2627	4.394e-155	492.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,46061@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
EH2_k127_2725280_2	998674.ATTE01000001_gene4277	5.912e-71	242.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,460JG@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
EH2_k127_2725280_3	1260251.SPISAL_07500	2.833e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1WYAY@135613|Chromatiales	135613|Chromatiales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
EH2_k127_2725280_0	472759.Nhal_2379	0.0	1898.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
EH2_k127_2727698_2	1120985.AUMI01000004_gene1349	1.401e-05	47.0	COG2984@1|root,COG4251@1|root,COG2984@2|Bacteria,COG4251@2|Bacteria,1UMZ2@1239|Firmicutes,4H9I5@909932|Negativicutes	1239|Firmicutes	T	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,PAS
EH2_k127_2727698_0	404380.Gbem_2024	3.007e-32	126.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
EH2_k127_2727698_1	640081.Dsui_1824	1.074e-15	89.0	COG2199@1|root,COG2199@2|Bacteria,1QKZ4@1224|Proteobacteria,2WHT2@28216|Betaproteobacteria,2KXS6@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,dCache_1
EH2_k127_2737161_4	227377.CBU_0530	7.525e-17	85.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1JDP1@118969|Legionellales	118969|Legionellales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_15,TPR_16,TPR_7
EH2_k127_2737161_1	1485544.JQKP01000011_gene758	6.957e-95	315.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria,44VEZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
EH2_k127_2737161_3	1266925.JHVX01000003_gene400	2.049e-62	221.0	COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2VTM1@28216|Betaproteobacteria,371R5@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
EH2_k127_2737161_2	765911.Thivi_3611	1.216e-65	237.0	COG0607@1|root,COG2905@1|root,COG0607@2|Bacteria,COG2905@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1WWD6@135613|Chromatiales	135613|Chromatiales	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
EH2_k127_2737161_0	1123393.KB891326_gene77	1.079e-161	522.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,1KSG6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
EH2_k127_2737563_0	396588.Tgr7_0875	7.787e-107	352.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
EH2_k127_2737563_2	765913.ThidrDRAFT_0706	4.073e-27	113.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2737563_1	765911.Thivi_2155	4.657e-74	252.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_2757198_2	216594.MMAR_2847	1.901e-49	178.0	2DQ16@1|root,334AZ@2|Bacteria,2IMJY@201174|Actinobacteria,23A9M@1762|Mycobacteriaceae	201174|Actinobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
EH2_k127_2757198_0	85643.Tmz1t_1473	1.331e-266	840.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
EH2_k127_2757198_1	85643.Tmz1t_1472	1.638e-120	396.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2VKGU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
EH2_k127_2762493_1	1249627.D779_1874	7.576e-75	264.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1X04E@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_2762493_0	713586.KB900536_gene2508	5.027e-113	372.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
EH2_k127_2762493_2	1049564.TevJSym_aj00140	2.151e-58	222.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1J4R0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
EH2_k127_2771826_1	870187.Thini_1791	2.963e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,461ME@72273|Thiotrichales	72273|Thiotrichales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
EH2_k127_2771826_0	1049564.TevJSym_al00300	7.476e-115	379.0	COG0842@1|root,COG0842@2|Bacteria,1QTBE@1224|Proteobacteria,1RNG9@1236|Gammaproteobacteria,1J4E1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
EH2_k127_2771826_2	2340.JV46_28190	1.222e-30	125.0	2AAM4@1|root,30ZYM@2|Bacteria,1RFTG@1224|Proteobacteria,1S4UQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
EH2_k127_2776275_0	396588.Tgr7_2002	1.236e-79	269.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1WVV4@135613|Chromatiales	135613|Chromatiales	L	AAA ATPase, central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
EH2_k127_2776275_1	870187.Thini_0422	6.424e-44	168.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,460XC@72273|Thiotrichales	72273|Thiotrichales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
EH2_k127_2778140_4	1038869.AXAN01000033_gene6914	3.716e-44	163.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1K0U8@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_2778140_2	396588.Tgr7_0771	1.181e-108	359.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
EH2_k127_2778140_1	713586.KB900536_gene1370	1.214e-110	366.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
EH2_k127_2778140_3	519989.ECTPHS_01894	1.894e-47	180.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1WWW5@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
EH2_k127_2778140_0	396588.Tgr7_0774	3.129e-111	362.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
EH2_k127_2794145_2	765913.ThidrDRAFT_2023	2.261e-27	113.0	COG0316@1|root,COG0316@2|Bacteria,1RKPC@1224|Proteobacteria,1SB76@1236|Gammaproteobacteria,1WYKT@135613|Chromatiales	135613|Chromatiales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH2_k127_2794145_0	396588.Tgr7_2170	1.593e-86	304.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1WWX3@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3
EH2_k127_2794145_1	713586.KB900536_gene998	3.087e-74	254.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH2_k127_2796032_0	1049564.TevJSym_bo00090	5.874e-171	543.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,1RR3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
EH2_k127_2798558_0	1123400.KB904756_gene2658	1.16e-144	467.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,460EH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
EH2_k127_2798558_1	519989.ECTPHS_03799	7.673e-33	128.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1WY0E@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
EH2_k127_2803922_4	1163617.SCD_n02539	0.000158	45.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH2_k127_2803922_3	396588.Tgr7_2517	4.608e-12	74.0	COG3678@1|root,COG3678@2|Bacteria,1NEDM@1224|Proteobacteria,1ST3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NPTU	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
EH2_k127_2803922_0	1415754.JQMK01000002_gene3065	3.293e-128	415.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,46451@72275|Alteromonadaceae	1236|Gammaproteobacteria	DT	COG1718 Serine threonine protein kinase involved in cell cycle control	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
EH2_k127_2803922_1	1163617.SCD_n00445	4.925e-22	102.0	2CM31@1|root,32SD0@2|Bacteria,1N2TZ@1224|Proteobacteria,2VUNK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2803922_2	1255043.TVNIR_3014	2.415e-13	73.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1WZ46@135613|Chromatiales	135613|Chromatiales	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
EH2_k127_281503_0	768671.ThimaDRAFT_4175	1.277e-289	910.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
EH2_k127_281503_1	331678.Cphamn1_2124	3.636e-20	100.0	COG0589@1|root,COG0589@2|Bacteria,1FF22@1090|Chlorobi	1090|Chlorobi	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2833312_0	765913.ThidrDRAFT_2135	2.572e-250	795.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1WWJS@135613|Chromatiales	135613|Chromatiales	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
EH2_k127_2833312_8	765911.Thivi_1959	1.34e-08	59.0	COG1918@1|root,COG1918@2|Bacteria,1N72T@1224|Proteobacteria,1SDMK@1236|Gammaproteobacteria,1WZ80@135613|Chromatiales	135613|Chromatiales	P	PFAM FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
EH2_k127_2833312_1	76114.ebA3595	9.74e-172	543.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
EH2_k127_2833312_5	1163617.SCD_n00430	2.182e-108	359.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
EH2_k127_2833312_7	1123393.KB891316_gene1494	9.757e-29	121.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria,1KRVF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
EH2_k127_2833312_3	572477.Alvin_1064	7.983e-127	413.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,1RP94@1236|Gammaproteobacteria,1WWKB@135613|Chromatiales	135613|Chromatiales	S	PFAM Radical SAM	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
EH2_k127_2833312_4	1163617.SCD_n00476	1.619e-111	367.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
EH2_k127_2833312_6	323261.Noc_2526	1.875e-64	224.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WY4F@135613|Chromatiales	135613|Chromatiales	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_2833312_2	1049564.TevJSym_ax00190	7.001e-138	443.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1J4GE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812	DHDPS
EH2_k127_2833312_9	614083.AWQR01000030_gene2810	1.891e-06	55.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,4ABTG@80864|Comamonadaceae	28216|Betaproteobacteria	M	Nlpbdapx family lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
EH2_k127_2848683_1	1163617.SCD_n02836	1.876e-43	168.0	2EZ32@1|root,33S9B@2|Bacteria,1NQJA@1224|Proteobacteria,2W11W@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2848683_0	292415.Tbd_0747	4.286e-67	233.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1KSGX@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
EH2_k127_2848683_2	292415.Tbd_0053	7.808e-10	64.0	2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2878537_0	261292.Nit79A3_2339	1.439e-299	921.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEM@28216|Betaproteobacteria,371TI@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
EH2_k127_2912718_0	1232410.KI421425_gene1552	7.902e-164	533.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH2_k127_2912718_1	1453501.JELR01000002_gene342	4.544e-105	346.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
EH2_k127_2919251_2	1123393.KB891316_gene1609	1.262e-53	190.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria,1KSB9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_2919251_0	381666.H16_A2210	1.228e-200	639.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2VI3X@28216|Betaproteobacteria,1K55G@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_2919251_3	292415.Tbd_2734	6.465e-20	104.0	COG0626@1|root,COG0626@2|Bacteria,1P41V@1224|Proteobacteria	1224|Proteobacteria	E	cystathionine gamma-synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2919251_1	2340.JV46_11310	2.225e-86	295.0	COG1073@1|root,COG1073@2|Bacteria,1R76C@1224|Proteobacteria,1RR34@1236|Gammaproteobacteria,1J69T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
EH2_k127_2921206_0	187272.Mlg_1865	8.161e-254	803.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
EH2_k127_2921206_1	472759.Nhal_2451	2.462e-133	428.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
EH2_k127_2921206_2	1123400.KB904752_gene862	2.606e-26	112.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
EH2_k127_2934927_0	1535422.ND16A_3437	1.205e-240	754.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,2Q6A8@267889|Colwelliaceae	1236|Gammaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
EH2_k127_2934927_5	1535422.ND16A_3438	5.537e-40	158.0	2CJ51@1|root,32S98@2|Bacteria,1N0AX@1224|Proteobacteria,1SAGU@1236|Gammaproteobacteria,2Q6XG@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
EH2_k127_2934927_4	1265503.KB905174_gene4308	7.811e-42	160.0	COG1331@1|root,COG1331@2|Bacteria,1NFE0@1224|Proteobacteria,1T23B@1236|Gammaproteobacteria,2Q6XX@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
EH2_k127_2934927_6	1286106.MPL1_00230	1.57e-33	136.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,4614W@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Smr	-	-	-	-	-	-	-	-	-	-	-	-	Smr
EH2_k127_2934927_1	519989.ECTPHS_03542	1.117e-98	330.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
EH2_k127_2934927_2	1026882.MAMP_01302	2.998e-85	287.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,460E3@72273|Thiotrichales	72273|Thiotrichales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_2934927_3	391615.ABSJ01000024_gene264	1.402e-58	216.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1J5VT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944	-	ko:K06194,ko:K12943	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
EH2_k127_2941800_1	713586.KB900536_gene2306	9.487e-54	193.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,1SZR6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2941800_0	1255043.TVNIR_1645	1.265e-57	205.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,1S620@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	nirL	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
EH2_k127_2941800_2	1244869.H261_00095	8.661e-05	46.0	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,2U81N@28211|Alphaproteobacteria,2JT8H@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
EH2_k127_2944863_1	1366050.N234_35005	8.718e-73	252.0	COG4320@1|root,COG4320@2|Bacteria,1N6EW@1224|Proteobacteria,2VN9A@28216|Betaproteobacteria,1K2DQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
EH2_k127_2944863_0	1304885.AUEY01000003_gene463	3.125e-89	301.0	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,42ZPF@68525|delta/epsilon subdivisions,2WUYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_294526_2	1121374.KB891588_gene3326	7.438e-71	241.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
EH2_k127_294526_1	314292.VAS14_07439	9.068e-109	362.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
EH2_k127_294526_0	396588.Tgr7_3214	9.93e-137	444.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
EH2_k127_2954600_0	1283300.ATXB01000001_gene507	5.281e-116	390.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XEJC@135618|Methylococcales	135618|Methylococcales	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
EH2_k127_2954600_1	472759.Nhal_3898	1.021e-85	289.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales	135613|Chromatiales	P	PFAM CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
EH2_k127_2955727_0	1163617.SCD_n01209	7.654e-197	617.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_2955727_1	1163617.SCD_n01210	8.8e-145	460.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
EH2_k127_2955727_2	1163617.SCD_n01211	7.615e-134	433.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
EH2_k127_2958005_2	1121374.KB891576_gene298	2.103e-19	91.0	29QWA@1|root,30BWM@2|Bacteria,1REIR@1224|Proteobacteria,1S50N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11,VanZ
EH2_k127_2958005_0	269797.Mbar_A1144	3.623e-70	248.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,2N940@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
EH2_k127_2958005_1	1123368.AUIS01000029_gene1283	3.215e-55	203.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2NCU3@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
EH2_k127_297453_0	1163617.SCD_n01213	4.776e-70	245.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
EH2_k127_297453_1	396588.Tgr7_0038	1.495e-31	126.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales	135613|Chromatiales	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_2984436_1	396588.Tgr7_1523	1.505e-72	257.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,1SI1R@1236|Gammaproteobacteria,1WWZB@135613|Chromatiales	135613|Chromatiales	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
EH2_k127_2984436_0	395493.BegalDRAFT_3110	7.582e-88	300.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,460UW@72273|Thiotrichales	72273|Thiotrichales	IQ	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_2984436_2	713586.KB900536_gene72	5.939e-46	171.0	COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1WX5T@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_2999238_0	1323663.AROI01000003_gene2225	5.987e-207	660.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Single-stranded-DNA-specific exonuclease	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
EH2_k127_2999238_3	1049564.TevJSym_ba00250	6.885e-43	169.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	rpfE	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2999238_2	1328313.DS2_08595	1.052e-86	293.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
EH2_k127_2999238_1	545264.KB898759_gene2660	1.242e-133	434.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
EH2_k127_3031953_0	1485545.JQLW01000007_gene839	1.663e-224	714.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria	1224|Proteobacteria	L	Atp-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
EH2_k127_3031953_1	1123393.KB891326_gene10	2.305e-47	173.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2W93N@28216|Betaproteobacteria,1KTHC@119069|Hydrogenophilales	1224|Proteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
EH2_k127_307107_5	765913.ThidrDRAFT_2100	3.887e-54	196.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_307107_6	713586.KB900536_gene1922	7.39e-30	120.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
EH2_k127_307107_3	857087.Metme_4614	2.194e-78	267.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XEE9@135618|Methylococcales	135618|Methylococcales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
EH2_k127_307107_0	768671.ThimaDRAFT_4172	6.098e-190	598.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
EH2_k127_307107_2	768671.ThimaDRAFT_4173	1.292e-103	343.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
EH2_k127_307107_4	1116472.MGMO_54c00130	7.616e-61	215.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales	135618|Methylococcales	S	pfam ammecr1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
EH2_k127_307107_7	314345.SPV1_04118	2.996e-22	99.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	-
EH2_k127_307107_1	1485545.JQLW01000005_gene1092	8.525e-105	344.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria	1224|Proteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
EH2_k127_3099652_0	1123393.KB891316_gene1613	5.807e-41	167.0	2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3099652_1	396588.Tgr7_0252	2.233e-30	126.0	COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,OMP_b-brl
EH2_k127_3134511_1	1384054.N790_01030	3.544e-165	528.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,1SM3A@1236|Gammaproteobacteria,1XDFJ@135614|Xanthomonadales	135614|Xanthomonadales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_3134511_0	472759.Nhal_3142	0.0	1362.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
EH2_k127_315103_0	580332.Slit_2150	4.228e-113	372.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_315103_2	261292.Nit79A3_1885	5.736e-94	317.0	COG0240@1|root,COG0240@2|Bacteria,1RED0@1224|Proteobacteria,2W2AD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
EH2_k127_315103_1	2340.JV46_22530	8.398e-109	356.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,1JBNA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
EH2_k127_3153996_2	391615.ABSJ01000054_gene1401	3.481e-81	276.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1J4J2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
EH2_k127_3153996_3	396588.Tgr7_1252	8.368e-70	244.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1WXEP@135613|Chromatiales	135613|Chromatiales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
EH2_k127_3153996_0	1123401.JHYQ01000042_gene1304	7.115e-223	694.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH2_k127_3153996_1	713586.KB900536_gene61	8.819e-110	360.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
EH2_k127_3157831_0	713586.KB900536_gene3089	3.818e-157	501.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
EH2_k127_3157831_1	396588.Tgr7_1034	3.205e-114	374.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
EH2_k127_318982_3	929562.Emtol_0859	1.093e-46	170.0	2C9B9@1|root,32RP0@2|Bacteria,4NSK0@976|Bacteroidetes,47RAS@768503|Cytophagia	976|Bacteroidetes	S	PFAM HopJ type III effector protein	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
EH2_k127_318982_0	472759.Nhal_0042	2.295e-232	731.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1WX9W@135613|Chromatiales	135613|Chromatiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
EH2_k127_318982_1	1349767.GJA_3788	4.628e-151	498.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,475M1@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS_4,Response_reg
EH2_k127_318982_2	472759.Nhal_2115	1.359e-54	196.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
EH2_k127_318982_4	1458275.AZ34_12785	5.584e-44	168.0	2A8H0@1|root,30XJ2@2|Bacteria,1REE0@1224|Proteobacteria,2W21U@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3194270_2	614083.AWQR01000035_gene3622	9.42e-34	136.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
EH2_k127_3194270_3	880072.Desac_1320	1.502e-28	121.0	COG0517@1|root,COG0517@2|Bacteria,1NKW9@1224|Proteobacteria,42XMW@68525|delta/epsilon subdivisions,2WT24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_3194270_0	289377.HL41_08260	3.943e-217	684.0	COG1055@1|root,COG1055@2|Bacteria,2GGUT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
EH2_k127_3194270_1	1163617.SCD_n02019	5.352e-40	151.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria	1224|Proteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
EH2_k127_319947_5	1217718.ALOU01000017_gene3308	5.019e-06	51.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,2VMIR@28216|Betaproteobacteria,1K17Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
EH2_k127_319947_1	395493.BegalDRAFT_2930	8.347e-74	253.0	COG0235@1|root,COG0235@2|Bacteria,1QAVF@1224|Proteobacteria,1RW3I@1236|Gammaproteobacteria,4628Z@72273|Thiotrichales	72273|Thiotrichales	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
EH2_k127_319947_0	519989.ECTPHS_02339	1.441e-77	268.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales	135613|Chromatiales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
EH2_k127_319947_2	1137799.GZ78_19540	4.857e-65	228.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1XJJR@135619|Oceanospirillales	135619|Oceanospirillales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
EH2_k127_319947_3	631362.Thi970DRAFT_01759	1.081e-46	173.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X024@135613|Chromatiales	135613|Chromatiales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal
EH2_k127_3231514_10	745411.B3C1_01765	6.045e-20	94.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1JBZ8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SCO1/SenC	scoP	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
EH2_k127_3231514_1	870187.Thini_0887	2.348e-151	486.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,460BG@72273|Thiotrichales	72273|Thiotrichales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	cyoA	-	1.10.3.10,1.9.3.1	ko:K02275,ko:K02297	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX2,COX2_TM,COX_ARM
EH2_k127_3231514_0	2340.JV46_24840	3.134e-291	900.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1J4DV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	iJN746.PP_0104	COX1
EH2_k127_3231514_6	870187.Thini_0884	1.075e-56	204.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	oxidase, assembly	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
EH2_k127_3231514_2	2340.JV46_24770	2.804e-136	438.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1J4UE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
EH2_k127_3231514_7	335283.Neut_2391	2.939e-40	158.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,372Z1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
EH2_k127_3231514_8	1163617.SCD_n02655	2.006e-26	117.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3231514_5	472759.Nhal_0068	3.155e-99	334.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales	135613|Chromatiales	O	cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
EH2_k127_3231514_4	2340.JV46_24540	3.911e-128	415.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1J4ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110	UbiA
EH2_k127_3231514_3	870187.Thini_0877	1.339e-128	425.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,1SKBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
EH2_k127_3231514_9	543913.D521_0822	1.471e-22	97.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,2WGR7@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_3237049_0	765913.ThidrDRAFT_3517	1.38e-192	613.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
EH2_k127_3250548_1	999141.GME_05300	1.9e-56	200.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1XNBZ@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
EH2_k127_3250548_0	349521.HCH_01557	6.202e-147	479.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XI1I@135619|Oceanospirillales	135619|Oceanospirillales	L	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C	-	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1
EH2_k127_3252147_0	930169.B5T_04011	7.291e-170	537.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales	135619|Oceanospirillales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
EH2_k127_3252147_3	396588.Tgr7_0032	2.229e-73	260.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1WYMY@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
EH2_k127_3252147_2	713586.KB900536_gene2167	5.449e-82	280.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales	135613|Chromatiales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
EH2_k127_3252147_1	765914.ThisiDRAFT_0667	2.284e-130	423.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1WVWF@135613|Chromatiales	135613|Chromatiales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
EH2_k127_3252147_4	1123399.AQVE01000003_gene2129	1.52e-48	184.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,461D0@72273|Thiotrichales	72273|Thiotrichales	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
EH2_k127_3254377_1	2340.JV46_04650	2.475e-33	134.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
EH2_k127_3254377_0	314345.SPV1_00095	1.29e-134	441.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_3267841_0	396588.Tgr7_1912	1.352e-78	267.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
EH2_k127_3267841_3	1121921.KB898708_gene1615	2.835e-22	100.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,2PP04@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
EH2_k127_3267841_2	697282.Mettu_0818	7.203e-30	127.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XFK3@135618|Methylococcales	135618|Methylococcales	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
EH2_k127_3267841_1	396588.Tgr7_1917	2.654e-70	242.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1WX51@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH2_k127_3282081_1	717772.THIAE_00745	7.077e-19	85.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
EH2_k127_3282081_0	519989.ECTPHS_13203	5.1e-254	788.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
EH2_k127_3307471_3	1162668.LFE_1389	2.266e-114	383.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
EH2_k127_3307471_5	1249627.D779_1951	2.661e-54	199.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1WWV8@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH2_k127_3307471_1	1123355.JHYO01000037_gene3668	4.481e-203	649.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
EH2_k127_3307471_0	203122.Sde_3155	3.651e-311	960.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,4640T@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
EH2_k127_3307471_6	1123400.KB904758_gene2248	2.458e-30	123.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,463H7@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
EH2_k127_3307471_4	1210884.HG799471_gene14698	5.139e-81	277.0	COG0500@1|root,COG0500@2|Bacteria,2J54N@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_3307471_2	713586.KB900536_gene594	6.46e-141	454.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales	135613|Chromatiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH2_k127_3325484_1	395493.BegalDRAFT_3088	2.53e-36	143.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,460PF@72273|Thiotrichales	72273|Thiotrichales	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
EH2_k127_3325484_0	395493.BegalDRAFT_2659	1.188e-36	147.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,462G2@72273|Thiotrichales	72273|Thiotrichales	U	General secretion pathway protein J	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
EH2_k127_3325484_2	1055815.AYYA01000009_gene2077	6.848e-12	71.0	COG4967@1|root,COG4967@2|Bacteria,1QWY7@1224|Proteobacteria,1T2ZG@1236|Gammaproteobacteria,3NTNZ@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
EH2_k127_333071_0	1279017.AQYJ01000026_gene57	0.0	1125.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
EH2_k127_3331963_1	1123368.AUIS01000009_gene2460	3.587e-185	590.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,2NCDY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
EH2_k127_3331963_0	396588.Tgr7_0358	9.302e-232	721.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales	135613|Chromatiales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
EH2_k127_3331963_2	765913.ThidrDRAFT_1568	4.681e-57	200.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WY87@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
EH2_k127_3331963_3	1211114.ALIP01000055_gene1563	6.118e-46	174.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1X3R5@135614|Xanthomonadales	135614|Xanthomonadales	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,RhlB
EH2_k127_3357506_0	713586.KB900536_gene2162	2.085e-75	269.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
EH2_k127_3357506_1	626887.J057_05091	4.765e-25	117.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317	HemX
EH2_k127_3382581_0	1121403.AUCV01000012_gene4121	1.709e-119	392.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,42PMI@68525|delta/epsilon subdivisions,2WN46@28221|Deltaproteobacteria,2MJXV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
EH2_k127_3382581_1	1121403.AUCV01000012_gene4120	2.381e-31	124.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MUK@68525|delta/epsilon subdivisions,2X5CN@28221|Deltaproteobacteria,2MJ17@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TOBE domain	potA	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
EH2_k127_3384351_0	381666.H16_B0948	3.063e-134	443.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,1KFF9@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
EH2_k127_3395308_3	944435.AXAJ01000006_gene3791	2.523e-23	117.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2VJ6I@28216|Betaproteobacteria,1K3YC@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM AsmA family protein	asmA	-	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
EH2_k127_3395308_0	701347.Entcl_0654	1.196e-107	360.0	COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,1RMUN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
EH2_k127_3395308_1	314285.KT71_09662	5.533e-32	132.0	COG3637@1|root,COG3637@2|Bacteria,1RI4B@1224|Proteobacteria,1S8IK@1236|Gammaproteobacteria,1J6HR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
EH2_k127_3419912_0	301.JNHE01000002_gene2156	2.116e-247	776.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1YEEV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH2_k127_3422726_1	713586.KB900536_gene2939	8.38e-78	267.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
EH2_k127_3422726_0	1303518.CCALI_00158	3.247e-234	736.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcSMS35_1347.EcSMS35_4486	PGI
EH2_k127_3422726_2	1517416.IDAT_12100	0.0003314	43.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,2QFX3@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
EH2_k127_3425220_0	519989.ECTPHS_00310	3.396e-130	426.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales	135613|Chromatiales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
EH2_k127_3425220_3	1286106.MPL1_04090	3.951e-44	166.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,460YW@72273|Thiotrichales	72273|Thiotrichales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
EH2_k127_3425220_2	396588.Tgr7_0880	4.735e-86	290.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1X2ET@135613|Chromatiales	135613|Chromatiales	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
EH2_k127_3425220_1	519989.ECTPHS_00325	1.055e-91	308.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1WWMY@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
EH2_k127_3426553_2	1123392.AQWL01000003_gene280	3.172e-24	102.0	28K74@1|root,2Z9VA@2|Bacteria,1R8MQ@1224|Proteobacteria,2VZJU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3426553_1	1163617.SCD_n02376	4.044e-88	297.0	2CPZ1@1|root,32SK5@2|Bacteria,1N2AX@1224|Proteobacteria,2W1HP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3426553_0	768671.ThimaDRAFT_0333	1.566e-101	334.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1WWUS@135613|Chromatiales	135613|Chromatiales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
EH2_k127_3429913_3	1163617.SCD_n01370	1.349e-29	119.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,2VYEF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3429913_1	1049564.TevJSym_ad00310	4.659e-127	416.0	2E6HP@1|root,3314Y@2|Bacteria,1QGPJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3429913_0	472759.Nhal_2673	0.0	1468.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
EH2_k127_3429913_5	1121374.KB891575_gene1310	1.569e-22	98.0	COG5302@1|root,COG5302@2|Bacteria,1NIFA@1224|Proteobacteria,1SD2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	-	-	-	ko:K19164	-	-	-	-	ko00000,ko02048	-	-	-	CcdA
EH2_k127_3429913_4	595494.Tola_2873	2.593e-28	117.0	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM CcdB protein	ccdB	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
EH2_k127_3429913_2	631362.Thi970DRAFT_01068	8.682e-101	332.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH2_k127_3463627_0	1198232.CYCME_0023	5.636e-171	541.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,45ZU6@72273|Thiotrichales	72273|Thiotrichales	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI
EH2_k127_3463627_1	930169.B5T_00620	1.192e-30	122.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
EH2_k127_3474987_0	1122194.AUHU01000003_gene2002	1.164e-68	247.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3474987_1	1122194.AUHU01000003_gene2003	4.017e-42	162.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,467DP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3474987_4	929558.SMGD1_0905	6.396e-16	88.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
EH2_k127_3474987_5	1298593.TOL_3361	3.407e-15	78.0	2E4HY@1|root,32ZD1@2|Bacteria,1N74N@1224|Proteobacteria,1SCRJ@1236|Gammaproteobacteria,1XMV7@135619|Oceanospirillales	135619|Oceanospirillales	S	Late competence development protein ComFB	-	-	-	-	-	-	-	-	-	-	-	-	ComFB
EH2_k127_3474987_2	590409.Dd586_0278	1.88e-37	147.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,2JC2F@204037|Dickeya	1236|Gammaproteobacteria	S	Belongs to the UPF0307 family	yjgA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
EH2_k127_3474987_6	1042375.AFPL01000023_gene1659	5.186e-09	66.0	COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,46DBE@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
EH2_k127_3474987_3	658612.MD26_03795	9.917e-20	90.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050	Formyl_trans_N
EH2_k127_3491083_0	1123400.KB904757_gene2177	6.918e-277	855.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,45ZVY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
EH2_k127_3491083_1	349521.HCH_05542	1.939e-157	514.0	COG0443@1|root,COG0443@2|Bacteria,1MUR1@1224|Proteobacteria,1RR7P@1236|Gammaproteobacteria,1XI97@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the heat shock protein 70 family	hscC	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH2_k127_3491083_2	397291.C804_04031	2.221e-05	51.0	COG0484@1|root,COG0653@1|root,COG0484@2|Bacteria,COG0653@2|Bacteria,1UIBD@1239|Firmicutes	1239|Firmicutes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,SEC-C,TPR_19,TPR_8
EH2_k127_3498462_0	1123518.ARWI01000001_gene1725	4.181e-168	532.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MUM1@1224|Proteobacteria,1SZKS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Iron hydrogenase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
EH2_k127_3498462_1	396588.Tgr7_0025	3.175e-87	293.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
EH2_k127_3499536_1	1163408.UU9_00964	6.652e-13	74.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1X44M@135614|Xanthomonadales	135614|Xanthomonadales	M	phospholipase	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
EH2_k127_3499536_0	266265.Bxe_A2154	4.646e-182	584.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
EH2_k127_3508338_1	870187.Thini_4352	2.894e-30	130.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
EH2_k127_3508338_0	396588.Tgr7_0331	1.22e-170	544.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
EH2_k127_3523789_2	1255043.TVNIR_1598	2.361e-58	209.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales	135613|Chromatiales	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
EH2_k127_3523789_0	1163617.SCD_n02930	3.91e-186	586.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
EH2_k127_3523789_3	1123399.AQVE01000002_gene2275	3.349e-55	198.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
EH2_k127_3523789_5	1123399.AQVE01000007_gene1131	3.474e-20	92.0	2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3523789_4	1123399.AQVE01000007_gene1145	2.075e-37	150.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,1RS8I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3523789_1	870187.Thini_1163	3.554e-107	357.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3523789_6	2340.JV46_19690	0.0001499	45.0	COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria,1J758@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
EH2_k127_3529460_0	1116472.MGMO_105c00150	2.446e-125	405.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XEVR@135618|Methylococcales	135618|Methylococcales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH2_k127_3529460_1	207954.MED92_05099	2.392e-55	195.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
EH2_k127_3546710_0	1123393.KB891316_gene1234	5.392e-172	546.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,1KSY5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
EH2_k127_3546710_2	580332.Slit_2343	2.274e-73	255.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
EH2_k127_3546710_4	1123401.JHYQ01000014_gene811	2.258e-13	71.0	COG0727@1|root,COG0727@2|Bacteria,1RGTX@1224|Proteobacteria,1S6FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH2_k127_3546710_3	159087.Daro_3013	7.385e-34	132.0	COG0727@1|root,COG0727@2|Bacteria,1RGTX@1224|Proteobacteria,2VT5K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH2_k127_3546710_1	395494.Galf_1244	2.347e-92	311.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,44V2F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Spermine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
EH2_k127_3610562_1	713586.KB900536_gene2252	7.53e-102	337.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_3610562_0	1049564.TevJSym_av00430	4.697e-204	644.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1J4CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
EH2_k127_3610562_4	1191523.MROS_0856	9.991e-54	192.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
EH2_k127_3610562_9	247633.GP2143_08504	2.599e-10	63.0	2DSN7@1|root,33GRM@2|Bacteria,1NQ0B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3610562_10	247633.GP2143_08504	8.558e-05	47.0	2DSN7@1|root,33GRM@2|Bacteria,1NQ0B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3610562_6	1049564.TevJSym_aq00120	3.609e-46	169.0	2F88A@1|root,340MG@2|Bacteria,1NXS1@1224|Proteobacteria,1SQ1P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
EH2_k127_3610562_7	159087.Daro_2812	1.161e-43	162.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria,2KWVD@206389|Rhodocyclales	206389|Rhodocyclales	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
EH2_k127_3610562_5	1123354.AUDR01000012_gene1637	1.208e-46	172.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KSP1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
EH2_k127_3610562_2	159087.Daro_2814	5.154e-77	263.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,2KZTT@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH2_k127_3610562_3	243231.GSU0721	1.834e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,430GK@68525|delta/epsilon subdivisions,2WVVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
EH2_k127_3610562_8	243231.GSU0723	7.913e-26	113.0	2DSEB@1|root,33FSP@2|Bacteria,1NIVA@1224|Proteobacteria,42WUP@68525|delta/epsilon subdivisions,2WSP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
EH2_k127_3611072_1	1116472.MGMO_91c00240	1.15e-60	211.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XDRF@135618|Methylococcales	135618|Methylococcales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
EH2_k127_3611072_3	519989.ECTPHS_01139	4.454e-39	151.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales	135613|Chromatiales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
EH2_k127_3611072_0	472759.Nhal_3814	3.861e-100	338.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
EH2_k127_3611072_2	713586.KB900536_gene2231	1.404e-59	215.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1WWDN@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
EH2_k127_3617115_1	857087.Metme_1570	2.541e-198	638.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
EH2_k127_3617115_0	580332.Slit_1541	0.0	1470.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,44WDS@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM CoA-binding domain protein	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
EH2_k127_3617115_2	580332.Slit_1540	3.066e-147	471.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,44W72@713636|Nitrosomonadales	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
EH2_k127_3617115_4	1123242.JH636434_gene3678	1.009e-67	233.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
EH2_k127_3617115_3	697282.Mettu_3537	3.914e-103	339.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1XG1T@135618|Methylococcales	135618|Methylococcales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
EH2_k127_3639869_2	765913.ThidrDRAFT_2252	4.575e-40	153.0	COG2703@1|root,COG2703@2|Bacteria,1N1XS@1224|Proteobacteria,1SAVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	hemerythrin-like metal-binding	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
EH2_k127_3639869_0	1123517.JOMR01000001_gene1223	2.307e-61	214.0	2D5Q1@1|root,32TJK@2|Bacteria,1N688@1224|Proteobacteria,1SS8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3639869_5	1123517.JOMR01000001_gene252	1.417e-21	95.0	2EGSV@1|root,33AIZ@2|Bacteria,1QR3B@1224|Proteobacteria,1RTW3@1236|Gammaproteobacteria,461FI@72273|Thiotrichales	72273|Thiotrichales	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
EH2_k127_3639869_3	1121403.AUCV01000008_gene1523	3.996e-33	132.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,42XZS@68525|delta/epsilon subdivisions,2WSXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
EH2_k127_3639869_4	314345.SPV1_00987	6.186e-22	96.0	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
EH2_k127_3639869_1	1121403.AUCV01000002_gene466	5.066e-46	168.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,42WC7@68525|delta/epsilon subdivisions,2WSEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CH	Flavodoxin domain	hemG	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2953	Flavodoxin_5
EH2_k127_3666995_2	396588.Tgr7_0573	1.374e-73	251.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales	135613|Chromatiales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
EH2_k127_3666995_0	396588.Tgr7_0572	4.832e-154	503.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1WX9B@135613|Chromatiales	135613|Chromatiales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
EH2_k127_3666995_3	1122201.AUAZ01000001_gene2465	8.584e-65	230.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the DnaA family. HdA subfamily	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
EH2_k127_3666995_4	1049564.TevJSym_af00840	3.696e-52	199.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1J69V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
EH2_k127_3666995_1	498211.CJA_1630	4.641e-151	485.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1FG2A@10|Cellvibrio	1236|Gammaproteobacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
EH2_k127_3666995_5	396588.Tgr7_2254	7.867e-52	189.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1WY1C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
EH2_k127_3673967_1	1026882.MAMP_02910	1.105e-76	271.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales	72273|Thiotrichales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
EH2_k127_3673967_2	519989.ECTPHS_08276	5.972e-45	164.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales	135613|Chromatiales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_3673967_0	1123400.KB904763_gene2419	1.455e-249	775.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales	72273|Thiotrichales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
EH2_k127_3698326_8	713586.KB900536_gene659	3.001e-58	206.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1WWNS@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
EH2_k127_3698326_5	395493.BegalDRAFT_2177	5.022e-119	388.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,46080@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
EH2_k127_3698326_10	717773.Thicy_1570	7.116e-38	147.0	COG1416@1|root,COG1416@2|Bacteria,1N0U1@1224|Proteobacteria,1SGKY@1236|Gammaproteobacteria,4629B@72273|Thiotrichales	72273|Thiotrichales	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
EH2_k127_3698326_1	1049564.TevJSym_ac01190	2.108e-177	562.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1J4DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
EH2_k127_3698326_0	396588.Tgr7_0972	5e-324	1001.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
EH2_k127_3698326_9	396588.Tgr7_0971	3.77e-55	198.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1WY2F@135613|Chromatiales	135613|Chromatiales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
EH2_k127_3698326_6	713586.KB900536_gene3029	3.751e-114	378.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales	135613|Chromatiales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
EH2_k127_3698326_7	519989.ECTPHS_10671	9.671e-82	278.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1WVXB@135613|Chromatiales	135613|Chromatiales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
EH2_k127_3698326_2	519989.ECTPHS_10666	1.788e-148	481.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales	135613|Chromatiales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH2_k127_3698326_4	519989.ECTPHS_10651	1.696e-123	404.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1WXIP@135613|Chromatiales	135613|Chromatiales	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
EH2_k127_3698326_3	519989.ECTPHS_08016	1.989e-133	431.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1WW9P@135613|Chromatiales	135613|Chromatiales	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
EH2_k127_3698326_11	2340.JV46_27210	4.696e-20	90.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
EH2_k127_3710864_1	1198232.CYCME_1108	1.328e-67	249.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1T223@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
EH2_k127_3710864_0	1255043.TVNIR_2084	1.082e-71	246.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S3WT@1236|Gammaproteobacteria,1WY7Z@135613|Chromatiales	135613|Chromatiales	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
EH2_k127_3710864_3	216142.LT40_01860	1.822e-56	206.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
EH2_k127_3710864_2	1027273.GZ77_17775	3.841e-66	231.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XJAU@135619|Oceanospirillales	135619|Oceanospirillales	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_3713312_3	1123392.AQWL01000002_gene1761	1.976e-48	183.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,1RHTS@1224|Proteobacteria,2VTRR@28216|Betaproteobacteria,1KSKZ@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Thioredoxin_3
EH2_k127_3713312_0	857087.Metme_2047	3.134e-131	427.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,1XEI0@135618|Methylococcales	135618|Methylococcales	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH2_k127_3713312_2	1288963.ADIS_2884	8.941e-51	184.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia	976|Bacteroidetes	Q	PFAM thioesterase superfamily	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
EH2_k127_3713312_5	631362.Thi970DRAFT_02369	1.234e-25	110.0	2DFIC@1|root,2ZRYR@2|Bacteria,1P7J0@1224|Proteobacteria,1SVFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3713312_4	525897.Dbac_2880	6.082e-33	131.0	COG1832@1|root,COG1832@2|Bacteria,1PUW7@1224|Proteobacteria,42T5D@68525|delta/epsilon subdivisions,2WPHZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
EH2_k127_3713312_1	391615.ABSJ01000037_gene826	1.461e-121	397.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1J5GE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH2_k127_3717706_0	498211.CJA_2381	6.147e-105	352.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,1FGDJ@10|Cellvibrio	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily	rlmM	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
EH2_k127_3720579_0	1123401.JHYQ01000005_gene184	3.115e-93	312.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,4608M@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
EH2_k127_3720579_1	292415.Tbd_2695	2.116e-64	227.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,1KRWY@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Ribosomal RNA adenine dimethylase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_3738828_0	754477.Q7C_704	1.138e-185	597.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
EH2_k127_3738828_1	305900.GV64_02855	3.084e-44	163.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
EH2_k127_3747276_0	857087.Metme_0468	7.055e-171	541.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1XEUN@135618|Methylococcales	135618|Methylococcales	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI
EH2_k127_3768313_0	261292.Nit79A3_1032	0.0	1377.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,372GZ@32003|Nitrosomonadales	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_3768313_1	261292.Nit79A3_1031	4.901e-129	413.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,371Q9@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_3768313_2	261292.Nit79A3_1030	5.706e-11	64.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2W36E@28216|Betaproteobacteria,373BV@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
EH2_k127_376851_0	396588.Tgr7_2532	9.245e-31	130.0	COG2433@1|root,COG2433@2|Bacteria,1QWB7@1224|Proteobacteria,1T3FV@1236|Gammaproteobacteria,1X2R3@135613|Chromatiales	135613|Chromatiales	S	Bacterial SH3 domain homologues	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
EH2_k127_376851_3	1349767.GJA_523	1.204e-17	90.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,474IC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
EH2_k127_376851_1	1121935.AQXX01000131_gene2878	1.426e-22	98.0	COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1XM6R@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
EH2_k127_3775463_3	391615.ABSJ01000022_gene323	1.994e-24	105.0	COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1J5ZC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0258 5'-3' exonuclease (including N-terminal domain of PolI)	exo	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
EH2_k127_3775463_1	396588.Tgr7_2971	6.687e-138	444.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1WX8X@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
EH2_k127_3775463_0	396588.Tgr7_2970	2.308e-188	595.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales	135613|Chromatiales	C	PFAM malic	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
EH2_k127_3775463_2	396588.Tgr7_2968	2.327e-46	178.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
EH2_k127_3775463_4	1121374.KB891577_gene3148	7.531e-08	53.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	50S ribosomal protein L31	rpmE	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
EH2_k127_377582_0	314345.SPV1_00095	1.731e-83	287.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_3780219_3	396588.Tgr7_0814	7.832e-72	250.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1WX6S@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
EH2_k127_3780219_1	686340.Metal_3260	2.081e-116	382.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XEJR@135618|Methylococcales	135618|Methylococcales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_3780219_2	1123393.KB891317_gene2318	7.883e-86	292.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1KS0Z@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
EH2_k127_3780219_5	555778.Hneap_2032	6.431e-47	174.0	COG2716@1|root,COG2716@2|Bacteria,1RB6J@1224|Proteobacteria,1S2A4@1236|Gammaproteobacteria,1WXZM@135613|Chromatiales	135613|Chromatiales	E	PFAM Amino acid-binding ACT	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
EH2_k127_3780219_4	572477.Alvin_0798	2.938e-63	221.0	COG0242@1|root,COG0242@2|Bacteria,1QM3A@1224|Proteobacteria,1RZHN@1236|Gammaproteobacteria,1WX64@135613|Chromatiales	135613|Chromatiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
EH2_k127_3780219_0	472759.Nhal_2331	1.768e-144	466.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1WVV3@135613|Chromatiales	135613|Chromatiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
EH2_k127_3783785_1	1163617.SCD_n00344	1.743e-53	196.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
EH2_k127_3783785_0	396588.Tgr7_0322	3.939e-108	362.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1WXAZ@135613|Chromatiales	135613|Chromatiales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_3810433_0	317025.Tcr_2136	6.383e-83	280.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,4602Z@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH2_k127_3810433_1	317025.Tcr_2137	7.039e-58	205.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,460PM@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
EH2_k127_3811866_2	1123368.AUIS01000019_gene1206	1.393e-23	103.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,2NCE0@225057|Acidithiobacillales	225057|Acidithiobacillales	T	His Kinase A (phospho-acceptor) domain	-	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_3811866_0	404589.Anae109_3474	2.445e-129	432.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions,2WQQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core,Transglut_i_TM
EH2_k127_3811866_1	765914.ThisiDRAFT_1026	1.029e-71	252.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
EH2_k127_3813361_1	1349767.GJA_3279	0.0001422	45.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,472MA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
EH2_k127_3813361_0	1238450.VIBNISOn1_560001	3.008e-69	250.0	COG2206@1|root,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,1RSQ4@1236|Gammaproteobacteria,1Y0CI@135623|Vibrionales	135623|Vibrionales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Hpt
EH2_k127_3827735_0	396588.Tgr7_0087	0.0	1202.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
EH2_k127_3827735_1	1005048.CFU_3528	1.307e-109	362.0	COG0564@1|root,COG0564@2|Bacteria,1MX5Y@1224|Proteobacteria,2VHUK@28216|Betaproteobacteria,4736Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
EH2_k127_3827735_2	553217.ENHAE0001_2020	8.459e-78	269.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,1S6M1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
EH2_k127_3827735_3	519989.ECTPHS_12009	7.638e-34	133.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1WWX9@135613|Chromatiales	135613|Chromatiales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
EH2_k127_3833518_0	1163617.SCD_n01124	3.218e-203	656.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,Cache_3-Cache_2,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_3,PAS_4,PAS_9
EH2_k127_3833518_2	1123393.KB891316_gene1450	1.337e-81	280.0	COG3221@1|root,COG3221@2|Bacteria,1PUJG@1224|Proteobacteria,2VKHU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_3833518_1	1122604.JONR01000039_gene3778	1.244e-130	422.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria,1XC99@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_30
EH2_k127_3833518_3	748247.AZKH_3839	1.801e-17	83.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KUA4@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
EH2_k127_3848022_1	1123401.JHYQ01000007_gene490	1.772e-61	216.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,45ZWG@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,HemN_C,Radical_SAM
EH2_k127_3848022_0	1415778.JQMM01000001_gene902	4.767e-121	399.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,1J5ZF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Acetyl-coenzyme A transporter 1	ampG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
EH2_k127_3860465_4	472759.Nhal_2508	4.116e-05	48.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,1S2YT@1236|Gammaproteobacteria,1X2AF@135613|Chromatiales	135613|Chromatiales	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
EH2_k127_3860465_3	83406.HDN1F_36360	5.994e-47	177.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,1JBRY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
EH2_k127_3860465_0	1415779.JOMH01000001_gene998	2.845e-164	538.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
EH2_k127_3860465_1	1163617.SCD_n02849	1.954e-112	371.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_3860465_2	1123401.JHYQ01000015_gene1409	4.517e-82	274.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
EH2_k127_3866032_0	1163617.SCD_n02228	6.759e-214	667.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
EH2_k127_3911889_2	1458275.AZ34_07480	8.206e-13	70.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,2VVB8@28216|Betaproteobacteria,4AF0B@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3911889_1	998674.ATTE01000001_gene3029	5.57e-35	141.0	28W7P@1|root,2ZI89@2|Bacteria,1N2SJ@1224|Proteobacteria,1SA34@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3911889_0	1122604.JONR01000009_gene2456	1.047e-38	147.0	COG0778@1|root,COG0778@2|Bacteria,1RDJ6@1224|Proteobacteria,1SXRF@1236|Gammaproteobacteria,1XAGK@135614|Xanthomonadales	135614|Xanthomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
EH2_k127_3919510_4	761193.Runsl_2092	7.07e-26	114.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
EH2_k127_3919510_0	929558.SMGD1_2852	9.379e-175	570.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42Q3N@68525|delta/epsilon subdivisions,2YMVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
EH2_k127_3919510_3	862908.BMS_0394	2.606e-63	226.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2MT12@213481|Bdellovibrionales,2WNU9@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
EH2_k127_3919510_2	709032.Sulku_2130	1.627e-84	293.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2YQJT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
EH2_k127_3919510_1	1537917.JU82_07460	2.094e-87	297.0	COG0859@1|root,COG0859@2|Bacteria,1NTHI@1224|Proteobacteria	1224|Proteobacteria	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
EH2_k127_3947739_0	1175306.GWL_00090	3.944e-55	200.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4743P@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
EH2_k127_395196_0	713586.KB900536_gene1403	3.649e-192	608.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
EH2_k127_395196_10	3988.XP_002537488.1	1.489e-09	63.0	COG5007@1|root,2SWF9@2759|Eukaryota	2759|Eukaryota	K	BolA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BolA
EH2_k127_395196_7	1236959.BAMT01000006_gene430	4.89e-48	181.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KME2@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
EH2_k127_395196_6	1026882.MAMP_01633	6.889e-51	184.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,460SM@72273|Thiotrichales	72273|Thiotrichales	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH2_k127_395196_4	754477.Q7C_1645	5.035e-100	333.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
EH2_k127_395196_2	243233.MCA1969	2.575e-121	395.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XET4@135618|Methylococcales	135618|Methylococcales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH2_k127_395196_1	1286106.MPL1_03333	2.949e-143	460.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,45ZSB@72273|Thiotrichales	72273|Thiotrichales	M	Arabinose 5-phosphate isomerase	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
EH2_k127_395196_5	1049564.TevJSym_ak00850	7.719e-76	258.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1J685@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECO26_1355.ECO26_4302	Hydrolase_3
EH2_k127_395196_9	1071679.BG57_21770	4.024e-20	97.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,1K3FT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
EH2_k127_395196_8	105559.Nwat_0297	1.018e-24	111.0	COG1934@1|root,COG3103@1|root,COG1934@2|Bacteria,COG3103@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1WYD5@135613|Chromatiales	135613|Chromatiales	T	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,SH3_3
EH2_k127_395196_3	519989.ECTPHS_01684	1.741e-103	341.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1WW0D@135613|Chromatiales	135613|Chromatiales	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_395196_11	187272.Mlg_2230	1.929e-05	46.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1WVZD@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
EH2_k127_3964791_1	316273.XCV1146	5.56e-108	354.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1X475@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH2_k127_3964791_2	1385517.N800_14405	2.738e-36	138.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
EH2_k127_3964791_0	395493.BegalDRAFT_2004	6.611e-125	404.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
EH2_k127_3967481_3	32057.KB217478_gene144	5.797e-85	300.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1G26V@1117|Cyanobacteria,1HQUB@1161|Nostocales	1117|Cyanobacteria	T	Histidine Phosphotransfer domain	-	-	-	ko:K13490	ko02020,ko02025,map02020,map02025	M00509	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	CheW,HATPase_c,Hpt,Response_reg
EH2_k127_3967481_6	497964.CfE428DRAFT_2818	8.477e-48	180.0	COG0835@1|root,COG0835@2|Bacteria,46VHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
EH2_k127_3967481_4	497964.CfE428DRAFT_2819	1.754e-78	278.0	COG1352@1|root,COG1352@2|Bacteria,46U91@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR,TPR_2
EH2_k127_3967481_7	1122604.JONR01000003_gene1379	4.287e-24	107.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1X945@135614|Xanthomonadales	135614|Xanthomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
EH2_k127_3967481_2	1173025.GEI7407_2171	8.044e-99	339.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1G1EU@1117|Cyanobacteria,1H86Z@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K13487	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CHASE3,HAMP,MCPsignal
EH2_k127_3967481_5	396588.Tgr7_1061	1.176e-48	177.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,1WYBY@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
EH2_k127_3967481_0	187272.Mlg_1870	1.727e-291	910.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
EH2_k127_3967481_1	582744.Msip34_1147	1.492e-134	446.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,2KKKJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
EH2_k127_3967481_8	1042377.AFPJ01000051_gene35	5.806e-06	53.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3970515_1	768671.ThimaDRAFT_0014	9.446e-113	375.0	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,1WWYY@135613|Chromatiales	135613|Chromatiales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
EH2_k127_3970515_0	396588.Tgr7_3240	7.051e-125	402.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales	135613|Chromatiales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH2_k127_398902_3	90814.KL370892_gene2230	3.922e-33	138.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
EH2_k127_398902_2	1163617.SCD_n00420	2.79e-69	242.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2W21C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
EH2_k127_398902_0	1163617.SCD_n00419	1.704e-144	481.0	COG2206@1|root,COG2206@2|Bacteria,1QWUX@1224|Proteobacteria,2VZ70@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,PAS_4
EH2_k127_398902_1	1163617.SCD_n01330	9.938e-108	374.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
EH2_k127_3999452_0	1452718.JBOY01000067_gene2343	1.463e-56	208.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
EH2_k127_3999452_1	323261.Noc_1172	2.602e-56	200.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
EH2_k127_4005020_1	870187.Thini_4364	5.767e-16	78.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,45ZSJ@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
EH2_k127_4005020_0	1049564.TevJSym_ap00360	6.453e-139	447.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1J4EQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUTI89_1310.UTI89_C0772,iZ_1308.Z0993	Aminotran_3
EH2_k127_4010876_0	1298593.TOL_1557	2.473e-75	266.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJW8@135619|Oceanospirillales	135619|Oceanospirillales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
EH2_k127_4015170_4	1123393.KB891316_gene2123	1.891e-10	61.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2W9BF@28216|Betaproteobacteria,1KT6Y@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
EH2_k127_4015170_1	1123393.KB891316_gene2122	4.487e-144	462.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KT21@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH2_k127_4015170_0	1123393.KB891316_gene2121	3.641e-156	502.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1KT46@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH2_k127_4015170_2	1123393.KB891316_gene2120	3.41e-92	310.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2W8Y6@28216|Betaproteobacteria,1KT87@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_4015170_3	1123393.KB891316_gene2119	4.116e-21	97.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Abc transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_4019578_0	1123355.JHYO01000034_gene564	5.032e-91	312.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2TTGG@28211|Alphaproteobacteria,36Y83@31993|Methylocystaceae	28211|Alphaproteobacteria	M	HlyD membrane-fusion protein of T1SS	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
EH2_k127_4019578_1	314285.KT71_17876	3.382e-23	107.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1J56F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_4024012_0	697282.Mettu_0485	6.228e-108	356.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1XDYG@135618|Methylococcales	135618|Methylococcales	E	Aminotransferase, class I	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_4024012_2	631362.Thi970DRAFT_03834	7.062e-48	174.0	COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1WYT7@135613|Chromatiales	135613|Chromatiales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
EH2_k127_4024012_1	317025.Tcr_1999	1.661e-94	324.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462B1@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH2_k127_4024012_3	1485544.JQKP01000003_gene80	2.119e-35	136.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,44VZV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YCII-related domain	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
EH2_k127_4046442_3	472759.Nhal_1157	1.117e-94	312.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH2_k127_4046442_4	765911.Thivi_0660	1.087e-34	138.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales	135613|Chromatiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
EH2_k127_4046442_2	748247.AZKH_1502	1.476e-125	412.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
EH2_k127_4046442_0	338969.Rfer_0832	6.545e-284	884.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4ABI0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
EH2_k127_4046442_1	1049564.TevJSym_bk00210	5.402e-207	651.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J4SA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	iYL1228.KPN_02462	AdoHcyase,AdoHcyase_NAD
EH2_k127_4076738_2	96561.Dole_0797	5.684e-24	105.0	COG3216@1|root,COG3216@2|Bacteria,1N1Q6@1224|Proteobacteria,42VQP@68525|delta/epsilon subdivisions,2WRUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062
EH2_k127_4076738_0	1485545.JQLW01000012_gene1679	1.792e-202	663.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria	1224|Proteobacteria	U	Periplasmic component of the Tol biopolymer transport system	VVA0929	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
EH2_k127_4076738_1	396588.Tgr7_0061	1.239e-107	354.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales	135613|Chromatiales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
EH2_k127_4094833_1	187272.Mlg_2608	5.518e-90	299.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales	135613|Chromatiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH2_k127_4094833_0	391615.ABSJ01000042_gene2203	9.262e-192	609.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1J50Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iE2348C_1286.E2348C_4372,iJN746.PP_4187	Pyr_redox_2,Pyr_redox_dim
EH2_k127_4094833_2	1034943.BN1094_00145	5.437e-29	117.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1JCPV@118969|Legionellales	118969|Legionellales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
EH2_k127_4101669_0	1177154.Y5S_01705	1.547e-184	584.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
EH2_k127_4101669_3	1173027.Mic7113_5982	3.729e-51	188.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,1H8T6@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
EH2_k127_4101669_1	2340.JV46_20220	9.14e-170	561.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J80W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS S-box diguanylate cyclase domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
EH2_k127_4101669_2	768671.ThimaDRAFT_0577	2.729e-61	213.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1WYEZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
EH2_k127_4114217_1	1266908.AQPB01000057_gene2236	2.265e-91	308.0	COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1WXRP@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH2_k127_4114217_3	472759.Nhal_3607	1.649e-58	213.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1WWE9@135613|Chromatiales	135613|Chromatiales	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH2_k127_4114217_2	754476.Q7A_2950	6.865e-87	294.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria,461S7@72273|Thiotrichales	72273|Thiotrichales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH2_k127_4114217_0	765914.ThisiDRAFT_0142	6.196e-115	379.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WWSE@135613|Chromatiales	135613|Chromatiales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_4119248_1	365044.Pnap_2845	6.718e-41	154.0	COG1595@1|root,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria,4AG5G@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_4119248_0	1123393.KB891329_gene947	1.301e-106	355.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VN77@28216|Betaproteobacteria,1KS6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_4141855_2	572477.Alvin_3068	1.068e-171	544.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
EH2_k127_4141855_8	207954.MED92_02036	4.325e-32	130.0	2EHMQ@1|root,33BDG@2|Bacteria,1NNTG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_4141855_1	396588.Tgr7_0117	1.161e-212	692.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_4141855_7	207954.MED92_15118	2.672e-40	154.0	COG1495@1|root,COG1495@2|Bacteria,1PSD8@1224|Proteobacteria,1TAIR@1236|Gammaproteobacteria,1XKDA@135619|Oceanospirillales	135619|Oceanospirillales	O	Disulfide bond formation protein DsbB	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
EH2_k127_4141855_4	870187.Thini_1080	5.036e-96	320.0	COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH2_k127_4141855_0	396588.Tgr7_2603	1.99e-216	679.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,1WWGB@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
EH2_k127_4141855_6	349521.HCH_04903	6.119e-45	172.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1XKR9@135619|Oceanospirillales	135619|Oceanospirillales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4141855_9	1168065.DOK_16933	1.172e-23	108.0	COG3063@1|root,COG3063@2|Bacteria,1N2T8@1224|Proteobacteria,1S9R8@1236|Gammaproteobacteria,1J72A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2
EH2_k127_4141855_5	177437.HRM2_23480	1.039e-54	198.0	COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,42PYR@68525|delta/epsilon subdivisions,2WJQF@28221|Deltaproteobacteria,2MICS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor P (EF-P) OB domain	efp-1	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
EH2_k127_4141855_3	1485544.JQKP01000011_gene740	3.511e-102	341.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria,44V5J@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
EH2_k127_4149454_0	1458275.AZ34_07565	9.986e-84	286.0	COG0789@1|root,COG0789@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,4ACBQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
EH2_k127_4149454_1	330214.NIDE3962	4.625e-83	281.0	COG0705@1|root,COG0705@2|Bacteria,3J16E@40117|Nitrospirae	40117|Nitrospirae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
EH2_k127_4149454_2	292415.Tbd_0067	2.238e-18	87.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,1RHTS@1224|Proteobacteria,2VTRR@28216|Betaproteobacteria,1KSKZ@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Thioredoxin_3
EH2_k127_4151970_6	713586.KB900536_gene1028	2.113e-60	216.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1WXF3@135613|Chromatiales	135613|Chromatiales	I	Membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
EH2_k127_4151970_12	396588.Tgr7_2218	7.311e-29	119.0	COG0607@1|root,COG0607@2|Bacteria,1QMXA@1224|Proteobacteria,1S6DI@1236|Gammaproteobacteria,1X2DB@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_4151970_4	412965.COSY_0218	8.364e-76	257.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,1RRM7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
EH2_k127_4151970_5	519989.ECTPHS_10806	6.77e-68	248.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
EH2_k127_4151970_11	998674.ATTE01000001_gene351	1.001e-32	130.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,461B4@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH2_k127_4151970_7	1049564.TevJSym_aw00360	2.271e-46	171.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH2_k127_4151970_10	519989.ECTPHS_10796	5.278e-36	139.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Sulphur oxidation protein SoxZ	soxZ	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
EH2_k127_4151970_2	1049564.TevJSym_ah00930	1.749e-99	332.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1J7ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
EH2_k127_4151970_1	1134474.O59_003264	5.602e-103	338.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1FGY9@10|Cellvibrio	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
EH2_k127_4151970_3	472759.Nhal_0186	2.438e-93	310.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
EH2_k127_4151970_8	396588.Tgr7_2227	3.565e-44	172.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales	135613|Chromatiales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
EH2_k127_4151970_9	765914.ThisiDRAFT_2251	3.47e-38	149.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
EH2_k127_4151970_0	1049564.TevJSym_be00170	1.284e-143	466.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
EH2_k127_4192389_1	1123401.JHYQ01000003_gene2130	1.629e-22	97.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,4621A@72273|Thiotrichales	72273|Thiotrichales	S	MCM2/3/5 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
EH2_k127_4192389_0	395493.BegalDRAFT_0160	6.355e-89	303.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,460QI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
EH2_k127_4209361_3	83406.HDN1F_07880	5.947e-14	74.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_30
EH2_k127_4209361_0	161528.ED21_23761	2.09e-132	437.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2UBMV@28211|Alphaproteobacteria,2K6P2@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4209361_4	1538295.JY96_13810	0.0002488	47.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria,1KN2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4219565_0	1276756.AUEX01000003_gene705	0.0	1047.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_4,PAS_9
EH2_k127_4219565_1	1163617.SCD_n01124	5.578e-58	207.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,Cache_3-Cache_2,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_3,PAS_4,PAS_9
EH2_k127_422706_0	1177179.A11A3_05614	6.907e-50	190.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,1XI5R@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
EH2_k127_4310683_1	1163617.SCD_n01931	6.459e-98	323.0	COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_4310683_2	1163617.SCD_n01930	3.247e-46	175.0	COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria	28216|Betaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4310683_0	1123400.KB904816_gene1617	1.286e-192	607.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,460AS@72273|Thiotrichales	72273|Thiotrichales	C	radical SAM protein YgiQ	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
EH2_k127_434370_6	1207076.ALAT01000019_gene829	0.000601	43.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1Z2UI@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	DNA polymerase III, chi subunit	holC	GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
EH2_k127_434370_0	395493.BegalDRAFT_2710	3.241e-200	636.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,460AF@72273|Thiotrichales	72273|Thiotrichales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
EH2_k127_434370_2	1049564.TevJSym_ar00210	1.02e-126	417.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1J4X2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
EH2_k127_434370_3	1123401.JHYQ01000038_gene1587	2.129e-101	336.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,45ZUU@72273|Thiotrichales	72273|Thiotrichales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
EH2_k127_434370_1	1049564.TevJSym_af00170	2.89e-148	483.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J571@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
EH2_k127_434370_4	882378.RBRH_02590	1.688e-51	183.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,1K7UM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
EH2_k127_4354774_0	1042375.AFPL01000043_gene1395	6.401e-171	547.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
EH2_k127_4354774_3	1123392.AQWL01000002_gene1843	1.468e-19	91.0	2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4354774_2	292415.Tbd_1126	4.433e-24	103.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
EH2_k127_4354774_1	396588.Tgr7_0025	5.307e-82	279.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
EH2_k127_4374322_0	395494.Galf_1542	1.118e-176	564.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,44WD5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4385849_2	1278307.KB907040_gene1962	2.705e-16	81.0	COG1550@1|root,COG1550@2|Bacteria,1NGDU@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
EH2_k127_4385849_0	472759.Nhal_1875	0.0	1263.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase, M16	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
EH2_k127_4385849_1	926550.CLDAP_01910	2.729e-63	227.0	COG1067@1|root,COG1067@2|Bacteria,2G64R@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
EH2_k127_4388573_1	1027273.GZ77_04980	1.522e-74	258.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1XJRE@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
EH2_k127_4388573_3	1122599.AUGR01000001_gene444	2.863e-21	96.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XM4X@135619|Oceanospirillales	135619|Oceanospirillales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
EH2_k127_4388573_0	870187.Thini_4167	6.645e-205	644.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
EH2_k127_4388573_2	640081.Dsui_2314	1.598e-49	177.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,2KUVF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
EH2_k127_4403253_1	396588.Tgr7_0930	1.14e-121	393.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH2_k127_4403253_0	1121918.ARWE01000001_gene244	2.745e-164	540.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43UE7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
EH2_k127_4403253_3	1049564.TevJSym_ac00470	5.082e-27	113.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,1J6VV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	FlhB HrpN YscU SpaS Family	flhB2	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
EH2_k127_4403253_4	1523503.JPMY01000031_gene3628	4.252e-20	104.0	COG3144@1|root,COG3144@2|Bacteria,1MV22@1224|Proteobacteria,1SCC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar hook-length control protein fliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
EH2_k127_4403253_5	472759.Nhal_3620	7.152e-19	94.0	COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria,1WZ98@135613|Chromatiales	135613|Chromatiales	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
EH2_k127_4403253_2	765914.ThisiDRAFT_0156	4.232e-82	276.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1WWMX@135613|Chromatiales	135613|Chromatiales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
EH2_k127_4403935_1	1121921.KB898713_gene1760	2.021e-52	187.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,2PMVP@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	H	Biotin and Thiamin Synthesis associated domain	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z0994	BATS,Radical_SAM
EH2_k127_4403935_0	243233.MCA1126	1.273e-111	368.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XE9P@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_4407169_2	391615.ABSJ01000042_gene2252	2.288e-69	236.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1J4KJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein, pilus retraction ATPase PilT	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_4407169_0	396588.Tgr7_2917	8.966e-198	621.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX16@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_4407169_1	519989.ECTPHS_03934	1.141e-80	272.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX4M@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_4437924_3	675813.VIB_000490	1.569e-97	329.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XSYN@135623|Vibrionales	135623|Vibrionales	J	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P	epmA	GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
EH2_k127_4437924_4	1158756.AQXQ01000012_gene1713	1.083e-88	295.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales	135613|Chromatiales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
EH2_k127_4437924_0	713586.KB900536_gene87	9.451e-113	373.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1WWYX@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
EH2_k127_4437924_2	396588.Tgr7_1230	4.398e-100	349.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,1X1SU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4437924_1	396588.Tgr7_1229	1.62e-100	343.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
EH2_k127_4442217_2	396588.Tgr7_1436	1.51e-132	430.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM RNA polymerase sigma factor RpoS	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_4442217_6	765910.MARPU_04670	7.456e-26	111.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,1X23R@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
EH2_k127_4442217_0	870187.Thini_4053	4.386e-195	616.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,45ZV6@72273|Thiotrichales	72273|Thiotrichales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
EH2_k127_4442217_5	1172190.M947_09640	8.215e-52	186.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
EH2_k127_4442217_1	1249480.B649_04235	1.963e-169	536.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
EH2_k127_4442217_3	335283.Neut_0648	4.271e-87	294.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
EH2_k127_4442217_4	754476.Q7A_323	1.171e-75	262.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1NPHH@1224|Proteobacteria,1RR8S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_4442217_7	1168067.JAGP01000001_gene661	2.142e-09	59.0	COG5001@1|root,COG5001@2|Bacteria,1R59J@1224|Proteobacteria,1SMVJ@1236|Gammaproteobacteria,461V3@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_4447717_1	1163617.SCD_n01692	4.214e-168	537.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
EH2_k127_4447717_3	1318628.MARLIPOL_14960	3.014e-60	213.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
EH2_k127_4447717_2	153948.NAL212_1483	5.037e-148	485.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,371PP@32003|Nitrosomonadales	28216|Betaproteobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
EH2_k127_4447717_0	1095769.CAHF01000015_gene2766	2.738e-192	604.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2VI2M@28216|Betaproteobacteria,473RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
EH2_k127_4469744_2	1430440.MGMSRv2_2263	3.92e-32	126.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2JSNX@204441|Rhodospirillales	204441|Rhodospirillales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
EH2_k127_4469744_0	1049564.TevJSym_aa02210	8.924e-209	657.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1J4FX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
EH2_k127_4469744_1	159087.Daro_4074	3.254e-57	200.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2VSQ1@28216|Betaproteobacteria,2KWPM@206389|Rhodocyclales	206389|Rhodocyclales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
EH2_k127_4489959_0	765914.ThisiDRAFT_1872	7.693e-130	427.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_4489959_1	1535422.ND16A_0977	1.631e-72	254.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,2Q6JQ@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_4489959_4	545264.KB898759_gene2643	0.0001966	51.0	COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SGPC@1236|Gammaproteobacteria,1WYNC@135613|Chromatiales	135613|Chromatiales	T	PFAM Anti sigma-E protein RseA	-	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
EH2_k127_4489959_2	391615.ABSJ01000002_gene483	4.521e-47	182.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1J65J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	MucB/RseB C-terminal domain	rseB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
EH2_k127_4489959_3	1123368.AUIS01000017_gene2572	3.446e-23	104.0	COG3086@1|root,COG3086@2|Bacteria	2|Bacteria	T	response to oxidative stress	rseC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
EH2_k127_4533651_2	396588.Tgr7_2695	2.603e-86	300.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,bPH_2
EH2_k127_4533651_4	1266914.ATUK01000011_gene2529	8.332e-29	121.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1WZKG@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
EH2_k127_4533651_1	396588.Tgr7_2538	9.406e-93	309.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1WX8R@135613|Chromatiales	135613|Chromatiales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
EH2_k127_4533651_0	1178482.BJB45_00360	5.143e-201	631.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales	135619|Oceanospirillales	IQ	catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
EH2_k127_4533651_3	1395571.TMS3_0100750	2.912e-52	189.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
EH2_k127_4533832_6	1265502.KB905944_gene692	3.186e-05	46.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,4ACTD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
EH2_k127_4533832_3	1470593.BW43_04886	8.07e-30	128.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
EH2_k127_4533832_5	1122243.KB903782_gene316	1.791e-05	49.0	2AZUS@1|root,31S44@2|Bacteria,1QPM2@1224|Proteobacteria,1TNBK@1236|Gammaproteobacteria,3NQAU@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4533832_2	631362.Thi970DRAFT_04589	1.215e-60	214.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
EH2_k127_4533832_1	314278.NB231_01574	9.871e-226	715.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
EH2_k127_4533832_0	159087.Daro_4090	1.173e-261	823.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,2VIRV@28216|Betaproteobacteria,2KVA3@206389|Rhodocyclales	206389|Rhodocyclales	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
EH2_k127_4534580_0	396588.Tgr7_1289	8.224e-199	632.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
EH2_k127_4535226_2	95619.PM1_0226800	1.939e-61	215.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
EH2_k127_4535226_3	1288826.MSNKSG1_12757	7.026e-44	160.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,468FR@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG1145 Ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4
EH2_k127_4535226_0	396588.Tgr7_0300	7.935e-209	663.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
EH2_k127_4535226_1	1565314.OA34_03790	2.065e-85	285.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2YN8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Molybdenum cofactor biosynthesis protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
EH2_k127_4535226_4	522772.Dacet_2500	1.477e-20	92.0	COG2094@1|root,COG2094@2|Bacteria,2GFSG@200930|Deferribacteres	200930|Deferribacteres	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
EH2_k127_4540047_2	2340.JV46_07570	2.048e-81	274.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
EH2_k127_4540047_4	247639.MGP2080_01326	1.027e-22	103.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome c5	cyc	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	Cytochrome_CBB3
EH2_k127_4540047_1	159087.Daro_3769	2.965e-102	341.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KV7X@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
EH2_k127_4540047_3	1121374.KB891580_gene1799	8.163e-63	218.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
EH2_k127_4540047_0	349521.HCH_02504	7.668e-106	351.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219,4.2.1.46	ko:K00091,ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
EH2_k127_4551374_0	870187.Thini_0473	1.73e-170	539.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales	72273|Thiotrichales	C	dihydrolipoamide dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
EH2_k127_4551374_2	1000565.METUNv1_02701	2.868e-84	293.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KVSS@206389|Rhodocyclales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23,OmpA
EH2_k127_4551374_1	1123393.KB891316_gene1945	7.668e-127	409.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KR9P@119069|Hydrogenophilales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	acrD	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
EH2_k127_4562050_5	1458357.BG58_09520	1.107e-50	182.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_4562050_2	292415.Tbd_0163	4.056e-209	652.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KRDZ@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
EH2_k127_4562050_3	396588.Tgr7_2890	1.411e-200	635.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
EH2_k127_4562050_1	1123393.KB891331_gene2909	5.285e-215	671.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1KS7D@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoglycerate kinase	-	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
EH2_k127_4562050_4	870187.Thini_2561	9.909e-193	603.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4604G@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
EH2_k127_4562050_0	2340.JV46_03550	1.849e-307	947.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
EH2_k127_4566242_0	563040.Saut_1560	2.548e-44	168.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_4566242_1	767434.Fraau_1363	1.499e-35	139.0	COG0859@1|root,COG0859@2|Bacteria,1MZGQ@1224|Proteobacteria,1S7TT@1236|Gammaproteobacteria,1X6DP@135614|Xanthomonadales	135614|Xanthomonadales	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4566242_2	667632.KB890218_gene278	1.785e-06	57.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VKMH@28216|Betaproteobacteria,1K14G@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
EH2_k127_4567115_1	279714.FuraDRAFT_1854	1.132e-119	390.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,2KPEY@206351|Neisseriales	206351|Neisseriales	K	Tex-like protein N-terminal domain protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
EH2_k127_4567115_0	1116472.MGMO_201c00070	2.937e-209	667.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XEJJ@135618|Methylococcales	135618|Methylococcales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_4571898_0	1163617.SCD_n00366	2.273e-239	746.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome d1, heme	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
EH2_k127_4571898_1	1049564.TevJSym_bo00190	1.043e-46	170.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1J616@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,EB_dh
EH2_k127_4573737_1	713586.KB900536_gene610	1.292e-77	261.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
EH2_k127_4573737_0	913325.N799_10925	1.216e-83	284.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1X4JK@135614|Xanthomonadales	135614|Xanthomonadales	E	alanine dehydrogenase	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
EH2_k127_4578850_1	391615.ABSJ01000050_gene1175	1.072e-27	118.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
EH2_k127_4578850_0	675812.VHA_000141	1.347e-53	193.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
EH2_k127_4578850_2	1188252.AJYK01000120_gene969	1.522e-10	69.0	COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1XWQW@135623|Vibrionales	135623|Vibrionales	NU	COG2165 Type II secretory pathway, pseudopilin PulG	epsH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
EH2_k127_4579570_0	4558.Sb02g031240.1	5.108e-96	318.0	COG0169@1|root,KOG0692@2759|Eukaryota,37S9N@33090|Viridiplantae,3GFW7@35493|Streptophyta,3KMZK@4447|Liliopsida,3ICTK@38820|Poales	35493|Streptophyta	E	3-dehydroquinate synthase	-	GO:0003674,GO:0003824,GO:0003856,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0012505,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019632,GO:0019752,GO:0031410,GO:0031982,GO:0031984,GO:0032787,GO:0033587,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044431,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:0097708,GO:0098791,GO:1901576,GO:1901615,GO:1901617	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH2_k127_4579570_1	713586.KB900536_gene1839	6.769e-51	183.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
EH2_k127_4587729_1	1165096.ARWF01000001_gene1422	3.373e-125	416.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria,2KKBN@206350|Nitrosomonadales	206350|Nitrosomonadales	U	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,SPOR
EH2_k127_4587729_0	1049564.TevJSym_ab01160	3.048e-139	460.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,1J5CC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway, component	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
EH2_k127_4587729_3	1163617.SCD_n00572	9.393e-41	168.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
EH2_k127_4587729_2	203122.Sde_1345	2.36e-97	324.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
EH2_k127_4589587_5	247633.GP2143_11944	3.078e-11	64.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4589587_0	1163617.SCD_n02330	4.062e-71	246.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
EH2_k127_4589587_3	640511.BC1002_5547	1.117e-26	116.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K7R1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4589587_6	266265.Bxe_C1259	0.0007114	47.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria	1224|Proteobacteria	M	surface antigen	omp	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti
EH2_k127_4589587_1	1332071.L581_1776	2.438e-38	151.0	COG4574@1|root,COG4574@2|Bacteria,1MZEN@1224|Proteobacteria,1S6Y9@1236|Gammaproteobacteria,4036J@613|Serratia	1236|Gammaproteobacteria	M	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases	eco	GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005623,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030288,GO:0030313,GO:0030414,GO:0031323,GO:0031324,GO:0031975,GO:0032268,GO:0032269,GO:0042597,GO:0043086,GO:0044092,GO:0044464,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772	-	ko:K08276	-	-	-	-	ko00000	-	-	-	Ecotin
EH2_k127_4589587_4	326297.Sama_2469	2.092e-23	107.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria,2QA0N@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
EH2_k127_4589587_2	1125863.JAFN01000001_gene972	4.936e-35	143.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
EH2_k127_4593075_6	1120999.JONM01000005_gene3870	1.543e-05	51.0	COG1639@1|root,COG1639@2|Bacteria,1MYFW@1224|Proteobacteria,2VTIV@28216|Betaproteobacteria,2KRC2@206351|Neisseriales	206351|Neisseriales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_4593075_3	1001585.MDS_0701	5.846e-53	198.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,1S8A4@1236|Gammaproteobacteria,1YHBW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4593075_1	1500894.JQNN01000001_gene1977	5.241e-113	375.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,472EQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH2_k127_4593075_0	1175306.GWL_23310	3.241e-126	409.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,473RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH2_k127_4593075_5	1122212.AULO01000014_gene1157	1.41e-23	114.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,1RYIU@1236|Gammaproteobacteria,1XKCX@135619|Oceanospirillales	135619|Oceanospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
EH2_k127_4593075_4	1123393.KB891317_gene2385	1.558e-51	193.0	COG3118@1|root,COG3118@2|Bacteria,1NWGI@1224|Proteobacteria,2W360@28216|Betaproteobacteria,1KRY1@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_4593075_2	1163617.SCD_n01952	6.127e-56	202.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria	1224|Proteobacteria	P	part of a sulfur-relay system	tusE	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_4598449_3	1249627.D779_0567	6.065e-64	222.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales	135613|Chromatiales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_4598449_5	1123020.AUIE01000048_gene3533	1.433e-35	136.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1YGRD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
EH2_k127_4598449_2	754476.Q7A_782	6.081e-69	243.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,460J5@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH2_k127_4598449_0	396588.Tgr7_2043	4.495e-165	527.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales	135613|Chromatiales	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
EH2_k127_4598449_1	1049564.TevJSym_au00100	6.399e-115	375.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1J5DH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0840	Hexapep,SATase_N
EH2_k127_4598449_4	1121935.AQXX01000125_gene822	1.015e-53	194.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales	135619|Oceanospirillales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
EH2_k127_4598449_6	634499.EpC_10290	1.429e-09	59.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,3X4KD@551|Erwinia	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
EH2_k127_459884_1	1123392.AQWL01000003_gene277	7.265e-33	130.0	COG0778@1|root,COG0778@2|Bacteria,1Q0ZY@1224|Proteobacteria,2WAFT@28216|Betaproteobacteria,1KSUE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
EH2_k127_459884_2	1094715.CM001373_gene2600	7.295e-12	71.0	28YDQ@1|root,2ZK87@2|Bacteria,1P5BI@1224|Proteobacteria,1STGK@1236|Gammaproteobacteria,1JEIB@118969|Legionellales	118969|Legionellales	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_459884_0	768671.ThimaDRAFT_2339	4.95e-67	235.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1WW02@135613|Chromatiales	135613|Chromatiales	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
EH2_k127_4609942_1	1485545.JQLW01000005_gene1093	1.451e-43	171.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
EH2_k127_4609942_0	1485545.JQLW01000005_gene1092	1.78e-216	683.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria	1224|Proteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
EH2_k127_461057_1	519989.ECTPHS_04935	1.889e-79	278.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH2_k127_461057_0	713586.KB900536_gene968	7.609e-99	335.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH2_k127_461057_2	686340.Metal_3725	2.862e-39	151.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XFBI@135618|Methylococcales	135618|Methylococcales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
EH2_k127_461057_3	626887.J057_12721	8.721e-11	70.0	COG2067@1|root,COG2067@2|Bacteria,1QXG1@1224|Proteobacteria,1T3B4@1236|Gammaproteobacteria,46D4R@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
EH2_k127_4610791_0	1163617.SCD_n00372	1.294e-162	517.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cytochrome d1, heme region	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
EH2_k127_4614208_0	396588.Tgr7_2004	1.885e-72	253.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales	135613|Chromatiales	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
EH2_k127_4614208_1	83406.HDN1F_33490	1.972e-37	141.0	COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,1SCUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
EH2_k127_4614208_2	83406.HDN1F_33500	5.74e-29	117.0	COG4634@1|root,COG4634@2|Bacteria,1NAN6@1224|Proteobacteria,1SCBD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4614208_4	314278.NB231_06381	0.0003798	44.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4614208_3	713586.KB900536_gene611	2.546e-24	104.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
EH2_k127_4619944_2	686340.Metal_3599	7.004e-64	220.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1XF09@135618|Methylococcales	135618|Methylococcales	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
EH2_k127_4619944_1	870187.Thini_2023	4.531e-86	290.0	COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
EH2_k127_4619944_3	396588.Tgr7_2545	1.67e-14	75.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4619944_0	1163617.SCD_n02065	1.112e-103	348.0	COG4360@1|root,COG4360@2|Bacteria,1RB5I@1224|Proteobacteria,2W0KI@28216|Betaproteobacteria	28216|Betaproteobacteria	F	ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_46230_1	1509403.GW12_26640	1.349e-29	119.0	COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria,1SCFK@1236|Gammaproteobacteria,3NPCG@468|Moraxellaceae	1236|Gammaproteobacteria	J	Protein of unknown function (DUF3565)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3565
EH2_k127_46230_0	580332.Slit_1711	5.377e-245	761.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44WAX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_4623049_0	713586.KB900536_gene2528	6.066e-149	480.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
EH2_k127_4623049_1	396588.Tgr7_2424	2.063e-84	287.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1WWMK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH2_k127_4623049_2	1122135.KB893170_gene2794	3.338e-19	94.0	COG5589@1|root,COG5589@2|Bacteria,1N6W5@1224|Proteobacteria,2UFIE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2390
EH2_k127_4630189_4	935567.JAES01000001_gene2208	5.56e-16	81.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1X84H@135614|Xanthomonadales	135614|Xanthomonadales	L	competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
EH2_k127_4630189_5	104623.Ser39006_02209	6.02e-09	57.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
EH2_k127_4630189_2	391615.ABSJ01000059_gene2177	2.609e-53	189.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1J6ER@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
EH2_k127_4630189_3	243265.plu2663	3.252e-41	154.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_4630189_0	1026882.MAMP_02694	1.593e-296	929.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,45ZNZ@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
EH2_k127_4630189_1	1049564.TevJSym_ad00110	3.005e-142	454.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1J559@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
EH2_k127_4631873_2	1286106.MPL1_09255	9.795e-21	94.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales	72273|Thiotrichales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
EH2_k127_4631873_1	1049564.TevJSym_aq00130	3.01e-68	236.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1J5X6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0241 Histidinol phosphatase and related phosphatases	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN746.PP_0059	Hydrolase_like
EH2_k127_4631873_0	870187.Thini_2394	3.768e-138	448.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
EH2_k127_465903_0	713586.KB900536_gene929	3.336e-124	420.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
EH2_k127_4672651_2	396588.Tgr7_3306	8.262e-120	391.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
EH2_k127_4672651_0	765914.ThisiDRAFT_2274	3.865e-271	840.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
EH2_k127_4672651_7	519989.ECTPHS_08813	3.108e-52	190.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
EH2_k127_4672651_6	754476.Q7A_225	3.08e-53	191.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales	72273|Thiotrichales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
EH2_k127_4672651_8	580332.Slit_2986	7.16e-35	134.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,44W3S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
EH2_k127_4672651_1	1123392.AQWL01000013_gene2375	5.884e-124	404.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
EH2_k127_4672651_9	1122139.KB907862_gene670	4.623e-05	51.0	COG3312@1|root,COG3312@2|Bacteria	2|Bacteria	C	ATP synthase I chain	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	iSSON_1240.SSON_3880	ATP-synt_I
EH2_k127_4672651_4	187272.Mlg_2877	3.633e-102	340.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
EH2_k127_4672651_3	396588.Tgr7_3314	1.673e-116	379.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales	135613|Chromatiales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH2_k127_4672651_5	1397527.Q670_03395	1.317e-57	206.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XJ8Z@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
EH2_k127_4673603_2	1304883.KI912532_gene1100	1.136e-63	221.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
EH2_k127_4673603_0	396588.Tgr7_2626	5.151e-93	308.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WX8K@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
EH2_k127_4673603_1	870187.Thini_0654	1.531e-85	286.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,460FE@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
EH2_k127_4673603_3	765913.ThidrDRAFT_2792	1.212e-12	68.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
EH2_k127_4678955_0	400668.Mmwyl1_2378	2.71e-225	716.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XIKF@135619|Oceanospirillales	135619|Oceanospirillales	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
EH2_k127_468610_1	243365.CV_1790	1.704e-129	421.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2VJE2@28216|Betaproteobacteria,2KQ26@206351|Neisseriales	206351|Neisseriales	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
EH2_k127_468610_0	1216007.AOPM01000085_gene877	1.845e-170	537.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,2Q0Y6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Ser protein kinase	yeaG	GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
EH2_k127_4688441_2	1283300.ATXB01000001_gene2102	5.394e-49	176.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1XGM7@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
EH2_k127_4688441_4	1283300.ATXB01000001_gene288	0.0002065	44.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1XGM7@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
EH2_k127_4688441_1	396588.Tgr7_0760	5.316e-54	193.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
EH2_k127_4688441_0	1080067.BAZH01000004_gene4132	5.8e-114	376.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,3WW6M@544|Citrobacter	1236|Gammaproteobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
EH2_k127_4688441_3	396588.Tgr7_0762	1.665e-18	89.0	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
EH2_k127_4697438_0	396588.Tgr7_2295	1.583e-180	571.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
EH2_k127_4702664_2	1266925.JHVX01000004_gene1115	3.997e-95	319.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,3727I@32003|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
EH2_k127_4702664_4	396588.Tgr7_1355	9.716e-71	246.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH2_k127_4702664_3	1001585.MDS_1674	1.073e-88	303.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1YCSQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_4702664_0	335283.Neut_2269	4.396e-279	880.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,373XP@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH2_k127_4702664_1	78898.MVEG_08315T0	1.993e-122	407.0	COG0790@1|root,KOG4308@1|root,KOG1550@2759|Eukaryota,KOG4308@2759|Eukaryota,39WUS@33154|Opisthokonta,3PBQR@4751|Fungi,1GY85@112252|Fungi incertae sedis	4751|Fungi	MOT	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
EH2_k127_4713699_0	261292.Nit79A3_2836	5.131e-215	668.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,372SP@32003|Nitrosomonadales	28216|Betaproteobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
EH2_k127_4713699_1	261292.Nit79A3_2837	4.923e-158	501.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,371YS@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
EH2_k127_4725193_0	1535422.ND16A_3444	6.333e-102	344.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,2Q8CP@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH2_k127_4725193_1	292415.Tbd_0164	1.31e-09	65.0	2FBEB@1|root,343K0@2|Bacteria,1P06H@1224|Proteobacteria,2W45V@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4727150_1	398527.Bphyt_1848	1.281e-30	121.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1K3BG@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_4727150_0	1121403.AUCV01000012_gene4119	1.258e-126	410.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,42M6K@68525|delta/epsilon subdivisions,2WKQC@28221|Deltaproteobacteria,2MK8H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
EH2_k127_4728417_1	574966.KB898649_gene211	1.125e-36	140.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIU2@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
EH2_k127_4728417_0	203122.Sde_3202	3.173e-79	276.0	COG1120@1|root,COG1120@2|Bacteria,1MWPV@1224|Proteobacteria,1T1UT@1236|Gammaproteobacteria,467EJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
EH2_k127_4728417_2	471881.PROPEN_00797	7.465e-06	55.0	COG0810@1|root,COG0810@2|Bacteria,1MZHE@1224|Proteobacteria,1SBCG@1236|Gammaproteobacteria,3Z25Y@583|Proteus	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C,TonB_N
EH2_k127_4744628_4	1198232.CYCME_0347	0.0009163	43.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,462AH@72273|Thiotrichales	72273|Thiotrichales	F	Adenylate cyclase, class-I	-	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
EH2_k127_4744628_0	580332.Slit_0020	2.537e-152	485.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	permeases of the drug metabolite transporter (Dmt) superfamily	yijE_2	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_4744628_2	998674.ATTE01000001_gene2650	3.654e-62	217.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,462R0@72273|Thiotrichales	72273|Thiotrichales	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH2_k127_4744628_3	90675.XP_010502896.1	1.517e-07	58.0	2CZ1E@1|root,2S7T1@2759|Eukaryota,388ZT@33090|Viridiplantae,3GXTP@35493|Streptophyta	35493|Streptophyta	S	AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
EH2_k127_4744628_1	1163617.SCD_n01091	1.224e-99	328.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria	28216|Betaproteobacteria	GK	ROK family	nagK	-	2.7.1.2,2.7.1.4,2.7.1.59	ko:K00845,ko:K00847,ko:K00884	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01201,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
EH2_k127_4756144_1	592316.Pat9b_3051	3.505e-107	351.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,3VYGX@53335|Pantoea	1236|Gammaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
EH2_k127_4756144_3	396588.Tgr7_0849	1.972e-52	186.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1WYID@135613|Chromatiales	135613|Chromatiales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
EH2_k127_4756144_4	765913.ThidrDRAFT_2873	1.02e-38	151.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1WYKN@135613|Chromatiales	135613|Chromatiales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
EH2_k127_4756144_0	1026882.MAMP_00646	2.39e-282	879.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
EH2_k127_4756144_6	29581.BW37_01717	1.585e-17	94.0	COG3712@1|root,COG3712@2|Bacteria,1QUYQ@1224|Proteobacteria,2WGKW@28216|Betaproteobacteria	28216|Betaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
EH2_k127_4756144_5	713586.KB900536_gene2946	3.434e-32	130.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
EH2_k127_4757800_1	1198452.Jab_2c02630	2.053e-73	254.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,477B7@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nosF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_4757800_3	396588.Tgr7_2952	1.389e-57	204.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1WYCE@135613|Chromatiales	135613|Chromatiales	H	PFAM molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
EH2_k127_4757800_4	395493.BegalDRAFT_2136	4.544e-21	95.0	COG1977@1|root,COG1977@2|Bacteria,1NHG7@1224|Proteobacteria	1224|Proteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
EH2_k127_4757800_2	396588.Tgr7_2950	2.184e-67	233.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1WY7V@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
EH2_k127_4757800_0	287.DR97_5876	4.182e-158	513.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1YCUE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1705)	eptA	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
EH2_k127_4763452_1	392500.Swoo_3888	3.701e-82	278.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,2QAIK@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
EH2_k127_4763452_2	1121878.AUGL01000014_gene1630	3.491e-77	260.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
EH2_k127_4763452_0	1049564.TevJSym_bd00260	1.635e-88	293.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113,ko:K11473	ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130	-	R00475,R00848	RC00029,RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
EH2_k127_4781154_1	2340.JV46_03550	1.62e-159	503.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
EH2_k127_4781154_2	2340.JV46_03560	1.191e-95	316.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1J8FE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_4781154_0	305900.GV64_22805	6.81e-241	762.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XHWC@135619|Oceanospirillales	135619|Oceanospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_4781154_4	316275.VSAL_I0575	0.0008692	46.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XT8V@135623|Vibrionales	135623|Vibrionales	K	Transcriptional activator	nhaR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_4781154_3	1206744.BAGL01000028_gene7580	9.457e-75	264.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4G001@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH2_k127_4787697_0	1123400.KB904817_gene1540	1.129e-94	320.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH2_k127_4899765_2	640081.Dsui_0818	9.939e-13	70.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KUKQ@206389|Rhodocyclales	206389|Rhodocyclales	S	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
EH2_k127_4899765_1	283942.IL0305	3.25e-27	115.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,1S44A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	belongs to the nudix hydrolase family	rppH_2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
EH2_k127_4899765_0	118173.KB235910_gene4327	3e-95	322.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH2_k127_490982_1	349521.HCH_00461	2.305e-83	284.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1XJ6A@135619|Oceanospirillales	135619|Oceanospirillales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH2_k127_490982_2	857087.Metme_2156	3.26e-72	251.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XG2F@135618|Methylococcales	135618|Methylococcales	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
EH2_k127_490982_3	697282.Mettu_3196	1.597e-47	175.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1XGBS@135618|Methylococcales	135618|Methylococcales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_490982_0	1049564.TevJSym_aa01010	7.418e-122	401.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1J4C5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	aer	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0016020,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0050918,GO:0051716,GO:0052128,GO:0052131,GO:0065007,GO:0071944	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,PAS_9,sCache_2
EH2_k127_4910238_0	1163617.SCD_n02163	2.076e-108	362.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WGST@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	rubB	-	1.18.1.1	ko:K05297,ko:K12265	ko00071,ko05132,map00071,map05132	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
EH2_k127_4910238_1	1439940.BAY1663_03904	1.888e-26	109.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center	rubA	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
EH2_k127_4911355_1	768671.ThimaDRAFT_3963	5.28e-56	200.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales	135613|Chromatiales	L	hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_4911355_0	502025.Hoch_2351	4.704e-99	333.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,42P5T@68525|delta/epsilon subdivisions,2WM91@28221|Deltaproteobacteria,2Z2Z9@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_4911355_2	1198232.CYCME_2364	7.751e-53	188.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,45ZTI@72273|Thiotrichales	72273|Thiotrichales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_4912376_0	1492922.GY26_17905	7.441e-227	707.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
EH2_k127_4915463_4	519989.ECTPHS_03969	1.647e-26	112.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales	135613|Chromatiales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
EH2_k127_4915463_3	396588.Tgr7_2924	4.607e-31	129.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the bacterial histone-like protein family	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
EH2_k127_4915463_2	391615.ABSJ01000050_gene1179	4.59e-32	137.0	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	General secretion pathway protein C	gspC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
EH2_k127_4915463_1	1049564.TevJSym_av00360	5.41e-190	617.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	xcsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
EH2_k127_4915463_0	396588.Tgr7_0226	5.366e-208	657.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
EH2_k127_4918438_4	2340.JV46_24270	3.195e-50	180.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1JA5R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	AIR synthase related protein, N-terminal domain	hypE	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
EH2_k127_4918438_1	1121033.AUCF01000027_gene2779	1.393e-163	522.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2TSVK@28211|Alphaproteobacteria,2JQIC@204441|Rhodospirillales	204441|Rhodospirillales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH2_k127_4918438_3	1121033.AUCF01000027_gene2778	2.077e-124	407.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria,2JT2G@204441|Rhodospirillales	204441|Rhodospirillales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
EH2_k127_4918438_2	1121033.AUCF01000027_gene2777	4.217e-138	449.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,2U4H3@28211|Alphaproteobacteria,2JVFR@204441|Rhodospirillales	204441|Rhodospirillales	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
EH2_k127_4918438_0	1163617.SCD_n00764	3.74e-291	902.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
EH2_k127_4918438_5	500637.PROVRUST_06098	1.026e-39	156.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,1S4H2@1236|Gammaproteobacteria,3Z6XJ@586|Providencia	1236|Gammaproteobacteria	C	Psort location Cytoplasmic, score 8.96	hybD	GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
EH2_k127_4918438_6	395493.BegalDRAFT_3214	3.338e-14	76.0	COG1773@1|root,COG1773@2|Bacteria,1N813@1224|Proteobacteria,1SCZ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	[NiFe]-hydrogenase assembly, chaperone, HybE	hoxT	-	-	-	-	-	-	-	-	-	-	-	NiFe-hyd_HybE
EH2_k127_4918945_5	402777.KB235898_gene5407	5.701e-18	84.0	COG5428@1|root,COG5428@2|Bacteria,1GAI1@1117|Cyanobacteria,1HDTQ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
EH2_k127_4918945_4	402777.KB235907_gene108	1.488e-18	87.0	2EGV4@1|root,33AMA@2|Bacteria,1GAZQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
EH2_k127_4918945_0	1255043.TVNIR_2716	2.453e-192	612.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales	135613|Chromatiales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
EH2_k127_4918945_2	1485544.JQKP01000018_gene576	2.88e-34	137.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
EH2_k127_4918945_3	1123487.KB892837_gene4036	6.376e-28	115.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KWWG@206389|Rhodocyclales	206389|Rhodocyclales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
EH2_k127_4918945_1	1238190.AMQY01000021_gene1616	6.509e-47	172.0	COG1216@1|root,COG1216@2|Bacteria,1N1TF@1224|Proteobacteria,1RPQU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	rfbN	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
EH2_k127_4926998_3	425104.Ssed_1747	2.467e-34	136.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
EH2_k127_4926998_2	589865.DaAHT2_1100	1.187e-112	374.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,42S0J@68525|delta/epsilon subdivisions,2X5EN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_4926998_0	439235.Dalk_3762	2.663e-187	611.0	COG0515@1|root,COG1639@1|root,COG2203@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,42M0G@68525|delta/epsilon subdivisions,2WJTM@28221|Deltaproteobacteria,2MI3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_4926998_1	187272.Mlg_2098	9.417e-159	503.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_4930616_0	349521.HCH_00019	1.401e-169	556.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
EH2_k127_4930616_1	1049564.TevJSym_aj00590	3.462e-93	313.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,1J5RV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
EH2_k127_4930616_2	1278309.KB907103_gene1051	3.239e-34	134.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHIX@135619|Oceanospirillales	135619|Oceanospirillales	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH2_k127_4950817_0	105559.Nwat_2215	1.007e-76	280.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1WW11@135613|Chromatiales	135613|Chromatiales	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_4950817_1	314278.NB231_05366	1.063e-76	267.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1WXIG@135613|Chromatiales	135613|Chromatiales	N	Flagellar rod assembly protein muramidase FlgJ	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
EH2_k127_4950817_2	1323663.AROI01000016_gene303	4.462e-20	90.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
EH2_k127_4954250_7	102125.Xen7305DRAFT_00018730	4.998e-08	64.0	COG1835@1|root,COG1835@2|Bacteria,1GB27@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
EH2_k127_4954250_6	1026882.MAMP_01063	6.614e-09	59.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
EH2_k127_4954250_5	391615.ABSJ01000039_gene1847	3.05e-14	83.0	COG3221@1|root,COG3221@2|Bacteria,1NBWA@1224|Proteobacteria	1224|Proteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_4954250_2	357804.Ping_2328	4.401e-129	421.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
EH2_k127_4954250_1	357804.Ping_2327	3.923e-130	426.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,2QJ72@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
EH2_k127_4954250_3	941639.BCO26_0153	1.185e-75	263.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus	91061|Bacilli	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
EH2_k127_4954250_4	1286106.MPL1_03568	2.432e-51	189.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,460UF@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH2_k127_4954250_0	1249627.D779_2643	8.328e-192	632.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
EH2_k127_4958680_2	338969.Rfer_3391	2.716e-17	94.0	COG0834@1|root,COG2203@1|root,COG2206@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,2W8ZE@28216|Betaproteobacteria,4AI3F@80864|Comamonadaceae	28216|Betaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
EH2_k127_4958680_0	1286093.C266_15975	3.461e-123	402.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,1K2JZ@119060|Burkholderiaceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
EH2_k127_4958680_1	1298593.TOL_1557	5.079e-45	174.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJW8@135619|Oceanospirillales	135619|Oceanospirillales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
EH2_k127_4961107_0	555778.Hneap_0393	1.468e-160	516.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
EH2_k127_4961107_2	312153.Pnuc_1236	2.343e-149	479.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2VIBF@28216|Betaproteobacteria,1K014@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	yejB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
EH2_k127_4961107_1	279714.FuraDRAFT_2242	3.513e-154	494.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2VHVN@28216|Betaproteobacteria,2KQAD@206351|Neisseriales	206351|Neisseriales	P	ABC transporter permease protein	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
EH2_k127_4961107_3	243275.TDE_1068	5.617e-36	141.0	COG0444@1|root,COG0444@2|Bacteria,2J62R@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
EH2_k127_4964974_0	580332.Slit_1358	3.878e-120	390.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,44WHF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
EH2_k127_4964974_1	1049564.TevJSym_by00060	2.391e-45	167.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,1SDCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4964974_2	1049564.TevJSym_bf00250	1.139e-13	76.0	COG2304@1|root,COG3509@1|root,COG4257@1|root,COG2304@2|Bacteria,COG3509@2|Bacteria,COG4257@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,FG-GAP_2
EH2_k127_4969042_0	1123401.JHYQ01000018_gene2401	7.597e-64	223.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
EH2_k127_4969042_1	395494.Galf_2298	9.066e-53	190.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,44VT0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
EH2_k127_4969042_2	713586.KB900536_gene308	6.455e-12	67.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1WYXK@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
EH2_k127_4984132_0	713586.KB900536_gene665	2.981e-97	327.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1WWK3@135613|Chromatiales	135613|Chromatiales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
EH2_k127_4984132_1	1049564.TevJSym_bc00200	9.172e-70	242.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1J5UI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
EH2_k127_4990620_1	488538.SAR116_1471	1.415e-51	189.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_4990620_0	292415.Tbd_2380	1.316e-81	275.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH2_k127_4991374_0	887062.HGR_05449	1.221e-111	366.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
EH2_k127_4991374_1	1045855.DSC_08780	5.913e-22	97.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
EH2_k127_4991779_4	207954.MED92_18428	2.266e-55	197.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
EH2_k127_4991779_9	1123517.JOMR01000001_gene1864	1.236e-20	92.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,4617P@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
EH2_k127_4991779_2	765913.ThidrDRAFT_1754	3.868e-75	255.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1WX2D@135613|Chromatiales	135613|Chromatiales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
EH2_k127_4991779_6	396588.Tgr7_2308	5.169e-45	166.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1WZ44@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
EH2_k127_4991779_1	396588.Tgr7_2309	6.731e-76	258.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1WXV2@135613|Chromatiales	135613|Chromatiales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
EH2_k127_4991779_5	519989.ECTPHS_13128	5.967e-55	194.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
EH2_k127_4991779_8	2340.JV46_07240	3.174e-37	142.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1J6KB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
EH2_k127_4991779_0	2340.JV46_07250	1.344e-89	297.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1J50H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
EH2_k127_4991779_7	1283300.ATXB01000001_gene623	1.073e-41	155.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1XFIK@135618|Methylococcales	135618|Methylococcales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
EH2_k127_4991779_3	713586.KB900536_gene1160	1.72e-62	215.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1WY84@135613|Chromatiales	135613|Chromatiales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
EH2_k127_4992322_0	1000565.METUNv1_02702	8.633e-294	913.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KVA4@206389|Rhodocyclales	206389|Rhodocyclales	U	efflux pump	-	-	-	ko:K18138,ko:K18146	ko01501,ko01503,map01501,map01503	M00647,M00649,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.40	-	-	ACR_tran
EH2_k127_5015193_0	754477.Q7C_2343	6.042e-128	426.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,460CQ@72273|Thiotrichales	72273|Thiotrichales	T	Sigma-54 interaction domain	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
EH2_k127_5015193_2	631362.Thi970DRAFT_03788	9.377e-74	262.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S1QJ@1236|Gammaproteobacteria,1WYXP@135613|Chromatiales	135613|Chromatiales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5015193_1	261292.Nit79A3_1925	4.27e-115	375.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,372S8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH2_k127_5015193_5	396588.Tgr7_2965	2.795e-05	50.0	COG4568@1|root,COG4568@2|Bacteria	2|Bacteria	K	rho-dependent transcription termination	rof	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	ROF
EH2_k127_5015193_3	1163617.SCD_n01952	4.206e-15	75.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria	1224|Proteobacteria	P	part of a sulfur-relay system	tusE	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_5021659_0	1049564.TevJSym_an00030	3.86e-286	888.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
EH2_k127_5021659_3	1123392.AQWL01000002_gene1981	1.943e-55	200.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KSU5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
EH2_k127_5021659_2	765913.ThidrDRAFT_2502	1.158e-127	416.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1WXW8@135613|Chromatiales	135613|Chromatiales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
EH2_k127_5021659_1	1122236.KB905141_gene1445	1.99e-145	464.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
EH2_k127_5042857_0	472759.Nhal_3684	2.49e-156	506.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
EH2_k127_5042857_2	387092.NIS_0340	1.012e-56	207.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2YMVQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
EH2_k127_5042857_1	395493.BegalDRAFT_1643	3.504e-90	304.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,461KC@72273|Thiotrichales	72273|Thiotrichales	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
EH2_k127_504563_0	765913.ThidrDRAFT_1625	2.662e-146	471.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1WWSU@135613|Chromatiales	135613|Chromatiales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
EH2_k127_504563_1	1209072.ALBT01000023_gene3955	5.251e-89	306.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1FFVK@10|Cellvibrio	1236|Gammaproteobacteria	HL	Thiamine monophosphate synthase	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
EH2_k127_5056875_2	1177154.Y5S_03739	1.757e-38	145.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1XNUT@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
EH2_k127_5056875_3	768671.ThimaDRAFT_0295	7.807e-28	118.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,1S5H3@1236|Gammaproteobacteria,1WYCN@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5056875_0	1198232.CYCME_2178	4.179e-95	317.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,45ZVH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM MoeZ MoeB domain	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
EH2_k127_5056875_4	400668.Mmwyl1_1536	1.273e-23	103.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XKZ1@135619|Oceanospirillales	135619|Oceanospirillales	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
EH2_k127_5056875_6	314287.GB2207_07083	2.85e-13	81.0	COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,1SAKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
EH2_k127_5056875_1	1242864.D187_007269	2.095e-92	319.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria	1224|Proteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
EH2_k127_5056875_5	83406.HDN1F_10340	2.36e-18	89.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
EH2_k127_5058482_4	292415.Tbd_0868	1.58e-52	187.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA_2
EH2_k127_5058482_0	1198232.CYCME_0490	7.449e-143	465.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,1RZ3M@1236|Gammaproteobacteria,460AN@72273|Thiotrichales	72273|Thiotrichales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
EH2_k127_5058482_2	1026882.MAMP_02992	4.235e-102	340.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1T1Q3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM periplasmic solute binding protein	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
EH2_k127_5058482_3	1123487.KB892846_gene512	1.342e-81	278.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
EH2_k127_5058482_1	1121935.AQXX01000116_gene5169	8.951e-124	402.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XHYI@135619|Oceanospirillales	135619|Oceanospirillales	L	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
EH2_k127_5060514_1	556268.OFAG_01045	7.895e-15	85.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,472KU@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
EH2_k127_5060514_0	472759.Nhal_0229	2.986e-135	448.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
EH2_k127_5130341_0	870187.Thini_1187	6.216e-315	970.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales	72273|Thiotrichales	P	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
EH2_k127_5130341_2	266264.Rmet_2272	1.139e-67	235.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1K0S5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
EH2_k127_5130341_3	1266908.AQPB01000035_gene137	2.239e-36	141.0	2EFAS@1|root,3393N@2|Bacteria,1NDQN@1224|Proteobacteria,1SSBD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5130341_1	261292.Nit79A3_2288	3.331e-118	384.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,372KM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
EH2_k127_5134134_12	1523503.JPMY01000045_gene126	1.761e-21	101.0	COG3152@1|root,COG3152@2|Bacteria,1N85G@1224|Proteobacteria,1SCMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5134134_0	1349767.GJA_2165	3.466e-213	670.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,2W0HG@28216|Betaproteobacteria,4727U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
EH2_k127_5134134_3	323261.Noc_1257	4e-61	216.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
EH2_k127_5134134_2	1170562.Cal6303_4993	1.422e-108	359.0	COG1230@1|root,COG1230@2|Bacteria,1G3AT@1117|Cyanobacteria,1HMIX@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
EH2_k127_5134134_9	1173024.KI912150_gene1407	1.842e-38	145.0	COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria,1JIVK@1189|Stigonemataceae	1117|Cyanobacteria	S	Ethanolamine utilisation protein EutQ	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
EH2_k127_5134134_7	261292.Nit79A3_3404	8.626e-47	176.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	gpmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH2_k127_5134134_8	195103.CPF_1908	3.259e-40	170.0	COG0444@1|root,COG0444@2|Bacteria,1TS8Q@1239|Firmicutes,2496U@186801|Clostridia,36DTY@31979|Clostridiaceae	186801|Clostridia	EP	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5134134_5	1517416.IDAT_07905	3.536e-54	193.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
EH2_k127_5134134_10	390235.PputW619_3567	2.421e-31	124.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1YYUE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
EH2_k127_5134134_11	1173026.Glo7428_0335	2.095e-23	104.0	COG4095@1|root,COG4095@2|Bacteria,1G874@1117|Cyanobacteria	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
EH2_k127_5134134_13	305900.GV64_07640	8.197e-21	98.0	COG5488@1|root,COG5488@2|Bacteria,1N9B7@1224|Proteobacteria,1SF1J@1236|Gammaproteobacteria,1XMU7@135619|Oceanospirillales	135619|Oceanospirillales	S	Integral membrane protein (DUF2244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
EH2_k127_5134134_1	713586.KB900536_gene1454	6.255e-202	642.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales	135613|Chromatiales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
EH2_k127_5134134_4	1123368.AUIS01000001_gene1890	2.95e-55	199.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_5134134_6	1318628.MARLIPOL_07394	4.59e-53	191.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
EH2_k127_5147103_0	1123399.AQVE01000020_gene1700	0.0	1090.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH2_k127_515337_0	1123518.ARWI01000001_gene1986	1.784e-157	509.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,45ZS2@72273|Thiotrichales	72273|Thiotrichales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
EH2_k127_515337_2	713586.KB900536_gene1497	3.217e-72	247.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1WWUP@135613|Chromatiales	135613|Chromatiales	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
EH2_k127_515337_4	1049564.TevJSym_aa00750	1.454e-35	146.0	COG1270@1|root,COG1270@2|Bacteria	2|Bacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
EH2_k127_515337_3	1049564.TevJSym_aa00740	1.711e-55	200.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1J6BG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73,5.4.2.12	ko:K02226,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
EH2_k127_515337_1	998674.ATTE01000001_gene4342	2.203e-106	354.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,45ZV5@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
EH2_k127_515337_5	396588.Tgr7_0565	1.074e-20	91.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
EH2_k127_515984_3	631362.Thi970DRAFT_04215	3.753e-57	200.0	COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria,1WWUG@135613|Chromatiales	135613|Chromatiales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
EH2_k127_515984_5	945713.IALB_2866	9.191e-42	157.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yiiD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K06323	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
EH2_k127_515984_7	1123401.JHYQ01000005_gene264	1.89e-18	89.0	28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_515984_0	870187.Thini_3759	3.283e-77	266.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,460NQ@72273|Thiotrichales	72273|Thiotrichales	S	PFAM 2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
EH2_k127_515984_8	1266914.ATUK01000012_gene201	1.104e-11	68.0	2C2HW@1|root,32U3B@2|Bacteria,1N2W5@1224|Proteobacteria,1SA05@1236|Gammaproteobacteria,1WYXJ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_515984_4	1123399.AQVE01000001_gene504	1.663e-46	170.0	COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_515984_1	1123401.JHYQ01000005_gene269	1.029e-66	235.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM CRISPR-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
EH2_k127_515984_2	396588.Tgr7_2184	3.681e-63	220.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales	135613|Chromatiales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
EH2_k127_5161219_0	1485545.JQLW01000001_gene1399	4.22e-92	310.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria	1224|Proteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
EH2_k127_5161219_2	697282.Mettu_3840	1.288e-24	104.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,1T1PC@1236|Gammaproteobacteria,1XERZ@135618|Methylococcales	135618|Methylococcales	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
EH2_k127_5161219_1	1121949.AQXT01000002_gene744	6.065e-36	139.0	COG0318@1|root,COG0318@2|Bacteria,1QVGC@1224|Proteobacteria,2TWFC@28211|Alphaproteobacteria,43WY7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding
EH2_k127_517889_1	519989.ECTPHS_05626	1.312e-60	217.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1WWU9@135613|Chromatiales	135613|Chromatiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
EH2_k127_517889_0	640081.Dsui_0894	2.567e-77	273.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
EH2_k127_5179935_1	765914.ThisiDRAFT_0926	4.481e-75	258.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH2_k127_5179935_2	1168065.DOK_00914	4.021e-11	70.0	COG3637@1|root,COG3637@2|Bacteria,1PES3@1224|Proteobacteria,1RWRV@1236|Gammaproteobacteria,1J77C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
EH2_k127_5179935_0	105559.Nwat_0444	3.815e-175	571.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales	135613|Chromatiales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
EH2_k127_519966_1	391615.ABSJ01000055_gene1354	3.18e-76	257.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
EH2_k127_519966_0	2340.JV46_03050	9.619e-163	527.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1J4SW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
EH2_k127_5209355_4	207954.MED92_00515	1.61e-117	382.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XH80@135619|Oceanospirillales	135619|Oceanospirillales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
EH2_k127_5209355_2	396588.Tgr7_0902	3.515e-153	494.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales	135613|Chromatiales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
EH2_k127_5209355_16	420662.Mpe_A1987	3.496e-13	72.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,1KMRR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
EH2_k127_5209355_8	1049564.TevJSym_bl00170	1.354e-101	338.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1J4V1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	HflC and HflK could regulate a protease	hflC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
EH2_k127_5209355_6	857087.Metme_2843	4.46e-111	371.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XDNN@135618|Methylococcales	135618|Methylococcales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
EH2_k127_5209355_1	1121943.KB899990_gene3681	8.514e-160	514.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales	135619|Oceanospirillales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
EH2_k127_5209355_15	751994.AGIG01000028_gene2049	2.002e-33	130.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1JAVT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
EH2_k127_5209355_7	1123399.AQVE01000033_gene1878	1.888e-109	362.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,4609E@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
EH2_k127_5209355_0	870187.Thini_3018	2.428e-233	742.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,45ZXP@72273|Thiotrichales	72273|Thiotrichales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
EH2_k127_5209355_5	396588.Tgr7_0894	8.122e-117	390.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1WX8Q@135613|Chromatiales	135613|Chromatiales	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
EH2_k127_5209355_12	634500.EbC_04480	5.816e-54	193.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,3X6AH@551|Erwinia	1236|Gammaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
EH2_k127_5209355_3	396588.Tgr7_0892	9.604e-145	475.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales	135613|Chromatiales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
EH2_k127_5209355_11	261292.Nit79A3_1924	1.399e-64	226.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,2WBZH@28216|Betaproteobacteria,3742E@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
EH2_k127_5209355_14	153948.NAL212_2513	5.378e-36	142.0	COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,2WC7I@28216|Betaproteobacteria,374EF@32003|Nitrosomonadales	28216|Betaproteobacteria	I	CDP-archaeol synthase	-	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
EH2_k127_5209355_9	765914.ThisiDRAFT_1509	5.726e-68	243.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S2ZF@1236|Gammaproteobacteria,1X2PF@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH2_k127_5209355_13	1158760.AQXP01000052_gene1713	8.394e-46	176.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH2_k127_5209355_10	1298593.TOL_1787	6.243e-65	223.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1XHWT@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
EH2_k127_5210187_1	365046.Rta_20930	2.56e-25	107.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,4AAN3@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH2_k127_5210187_2	398579.Spea_1688	1.997e-16	89.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,2Q91J@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
EH2_k127_5210187_0	391615.ABSJ01000029_gene1940	5.255e-219	700.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1J4IV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
EH2_k127_5228686_8	713586.KB900536_gene1665	1.826e-83	281.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH2_k127_5228686_6	1123399.AQVE01000007_gene1209	1.464e-101	337.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
EH2_k127_5228686_10	519989.ECTPHS_06342	6.957e-78	266.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1WX4R@135613|Chromatiales	135613|Chromatiales	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
EH2_k127_5228686_14	582744.Msip34_0434	2.008e-63	220.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,2KMKZ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
EH2_k127_5228686_3	1123368.AUIS01000011_gene1180	4.166e-136	451.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
EH2_k127_5228686_4	1049564.TevJSym_ag00320	8.693e-128	418.0	COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1J5KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3412,iSDY_1059.SDY_0027	AdoMet_dc
EH2_k127_5228686_16	1121904.ARBP01000007_gene2957	1.714e-53	192.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
EH2_k127_5228686_21	1123228.AUIH01000026_gene3875	5.761e-18	87.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,1XKWS@135619|Oceanospirillales	135619|Oceanospirillales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
EH2_k127_5228686_5	396588.Tgr7_0518	8.783e-103	344.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1WWKK@135613|Chromatiales	135613|Chromatiales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
EH2_k127_5228686_1	1026882.MAMP_00134	2.791e-237	740.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
EH2_k127_5228686_0	754476.Q7A_2838	1.825e-237	743.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
EH2_k127_5228686_20	713586.KB900536_gene1603	1.761e-34	137.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
EH2_k127_5228686_2	396588.Tgr7_0514	1.286e-193	608.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1WW91@135613|Chromatiales	135613|Chromatiales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
EH2_k127_5228686_11	519989.ECTPHS_09248	9.711e-77	266.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales	135613|Chromatiales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
EH2_k127_5228686_18	765914.ThisiDRAFT_1911	2.972e-35	141.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales	135613|Chromatiales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
EH2_k127_5228686_13	396588.Tgr7_2689	2.016e-66	236.0	28K4C@1|root,2Z9TB@2|Bacteria,1R4FT@1224|Proteobacteria,1RSIZ@1236|Gammaproteobacteria,1WWH0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5228686_23	314285.KT71_18047	3.292e-08	60.0	COG0610@1|root,COG0610@2|Bacteria,1R89U@1224|Proteobacteria,1RZRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5228686_24	1121019.AUMN01000032_gene3102	1.397e-06	56.0	COG0610@1|root,COG0610@2|Bacteria,2GYTJ@201174|Actinobacteria	201174|Actinobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5228686_19	105559.Nwat_0118	9.524e-35	138.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_5228686_9	1049564.TevJSym_ag00310	3.556e-82	278.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1J5PX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
EH2_k127_5228686_7	335283.Neut_0446	2.459e-86	300.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VITX@28216|Betaproteobacteria,374MN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S double cluster binding domain	lutA	-	-	ko:K11473,ko:K18928	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
EH2_k127_5228686_17	748247.AZKH_0479	1.41e-43	160.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KWNM@206389|Rhodocyclales	206389|Rhodocyclales	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
EH2_k127_5228686_12	1035839.AFNK01000007_gene1705	9.108e-72	244.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1Y83E@135625|Pasteurellales	135625|Pasteurellales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
EH2_k127_5228686_15	305900.GV64_20525	5.051e-56	198.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XJHH@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
EH2_k127_5228686_22	1123514.KB905901_gene85	2.391e-12	71.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,4632G@72273|Thiotrichales	72273|Thiotrichales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
EH2_k127_524060_0	1045855.DSC_01065	3.222e-138	446.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1X36F@135614|Xanthomonadales	135614|Xanthomonadales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
EH2_k127_5256001_0	765910.MARPU_16625	2.469e-78	272.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1WX2U@135613|Chromatiales	135613|Chromatiales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
EH2_k127_5256001_1	396588.Tgr7_0577	1.103e-26	112.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
EH2_k127_5264323_2	478741.JAFS01000001_gene1532	3.916e-05	48.0	COG1073@1|root,COG1073@2|Bacteria,46V25@74201|Verrucomicrobia,37G63@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
EH2_k127_5264323_1	1265313.HRUBRA_02317	2.987e-40	155.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1J6M3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	aspartyl protease	orf	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
EH2_k127_5264323_0	1123228.AUIH01000004_gene1080	3.022e-67	235.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XJW4@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_526678_10	1158292.JPOE01000005_gene886	2.108e-27	113.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2VSFK@28216|Betaproteobacteria,1KP1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
EH2_k127_526678_5	1458357.BG58_18250	5.554e-102	335.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,1K7KF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
EH2_k127_526678_11	1123257.AUFV01000002_gene2506	2.585e-27	114.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1X85Y@135614|Xanthomonadales	135614|Xanthomonadales	N	Bacterial export proteins, family 3	-	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
EH2_k127_526678_7	396588.Tgr7_1333	1.131e-82	282.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1WWVK@135613|Chromatiales	135613|Chromatiales	N	Role in flagellar biosynthesis	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
EH2_k127_526678_2	314278.NB231_02063	8.918e-118	390.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1WW1K@135613|Chromatiales	135613|Chromatiales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
EH2_k127_526678_0	765914.ThisiDRAFT_0149	1.284e-288	901.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1WVWU@135613|Chromatiales	135613|Chromatiales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
EH2_k127_526678_4	314278.NB231_02073	2.209e-105	357.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1WXF1@135613|Chromatiales	135613|Chromatiales	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
EH2_k127_526678_3	1049564.TevJSym_aw00490	1.024e-110	365.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1J4GX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
EH2_k127_526678_6	187272.Mlg_0985	2.146e-84	286.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_526678_8	1215092.PA6_039_00290	2.616e-66	228.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1YFTG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KT	Response regulator receiver domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_526678_9	187272.Mlg_0987	1.577e-59	214.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1WWSX@135613|Chromatiales	135613|Chromatiales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	-	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
EH2_k127_526678_1	1109445.AGSX01000070_gene88	9.647e-242	767.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1Z069@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH2_k127_526678_12	1123054.KB907714_gene693	1.147e-09	59.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WWSE@135613|Chromatiales	135613|Chromatiales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_5277683_2	648757.Rvan_3390	6.638e-15	75.0	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,2UCKE@28211|Alphaproteobacteria,3N8PE@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
EH2_k127_5277683_1	1384056.N787_02640	2.95e-64	224.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1X514@135614|Xanthomonadales	135614|Xanthomonadales	S	carbonic	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
EH2_k127_5277683_0	519989.ECTPHS_07411	2.171e-96	320.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
EH2_k127_5292014_0	396588.Tgr7_0997	1.137e-77	261.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
EH2_k127_5292014_3	545276.KB898724_gene1870	9.947e-17	81.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
EH2_k127_5292014_2	631362.Thi970DRAFT_00554	3.122e-42	156.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1WYHG@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
EH2_k127_5292014_1	1049564.TevJSym_ap00530	5.434e-71	245.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S4ZA@1236|Gammaproteobacteria,1JBRZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
EH2_k127_529329_0	1396858.Q666_10085	5.757e-22	108.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_5294909_0	1163617.SCD_n00781	1.04e-159	512.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_5294909_1	686340.Metal_0122	2.175e-101	351.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XEJY@135618|Methylococcales	135618|Methylococcales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
EH2_k127_5294909_2	697282.Mettu_1928	8.691e-87	303.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
EH2_k127_5301609_1	1026882.MAMP_01479	3.555e-273	855.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales	72273|Thiotrichales	E	peptidase	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
EH2_k127_5301609_0	713586.KB900536_gene2143	0.0	1167.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
EH2_k127_5301609_2	396588.Tgr7_0003	4.088e-47	177.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1WYPF@135613|Chromatiales	135613|Chromatiales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
EH2_k127_53055_1	349521.HCH_02504	2.956e-47	183.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219,4.2.1.46	ko:K00091,ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
EH2_k127_53055_0	754476.Q7A_2452	6.282e-84	286.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,1S31N@1236|Gammaproteobacteria,460FD@72273|Thiotrichales	72273|Thiotrichales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
EH2_k127_53055_2	96561.Dole_2423	0.00062	50.0	COG3103@1|root,COG3103@2|Bacteria,1R4IV@1224|Proteobacteria,42UPZ@68525|delta/epsilon subdivisions,2WQDF@28221|Deltaproteobacteria,2MKNS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5311422_0	519989.ECTPHS_13223	2.5e-300	928.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
EH2_k127_5311422_1	519989.ECTPHS_13218	3.843e-161	510.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
EH2_k127_5313688_0	261292.Nit79A3_0201	5.342e-278	856.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,371SR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_5313688_1	261292.Nit79A3_0200	2.206e-197	617.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,3722K@32003|Nitrosomonadales	28216|Betaproteobacteria	T	PhoH-like protein	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
EH2_k127_5313688_3	261292.Nit79A3_0199	9.725e-88	290.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,3735J@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
EH2_k127_5313688_2	261292.Nit79A3_0198	1.512e-104	340.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,372B3@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
EH2_k127_53285_0	1163617.SCD_n02368	1.148e-259	809.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,2VQU4@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH2_k127_53285_1	596154.Alide2_2495	1.317e-208	657.0	COG0446@1|root,COG0446@2|Bacteria,1PP77@1224|Proteobacteria,2W9FF@28216|Betaproteobacteria,4AA7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
EH2_k127_53285_2	1163617.SCD_n01922	1.371e-56	202.0	COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_53285_3	1123392.AQWL01000003_gene304	5.831e-13	69.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria,1KT1X@119069|Hydrogenophilales	119069|Hydrogenophilales	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
EH2_k127_534291_6	498211.CJA_2082	2.563e-22	98.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,1FGIB@10|Cellvibrio	1236|Gammaproteobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
EH2_k127_534291_2	1129374.AJE_02701	1.443e-126	415.0	COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,464PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
EH2_k127_534291_0	1123401.JHYQ01000037_gene1653	1.958e-199	628.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,45ZR9@72273|Thiotrichales	72273|Thiotrichales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
EH2_k127_534291_7	298386.PBPRB1058	2.722e-06	53.0	2DQ5V@1|root,334VY@2|Bacteria,1NFQC@1224|Proteobacteria,1SG35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
EH2_k127_534291_3	1123367.C666_07760	1.204e-66	236.0	COG1845@1|root,COG1845@2|Bacteria,1RDNK@1224|Proteobacteria,2VKAY@28216|Betaproteobacteria,2KVB4@206389|Rhodocyclales	206389|Rhodocyclales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
EH2_k127_534291_4	870187.Thini_2548	2.017e-47	171.0	COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,1S609@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_534291_1	1286106.MPL1_08564	1.77e-167	531.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,45ZQT@72273|Thiotrichales	72273|Thiotrichales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
EH2_k127_534291_5	1121035.AUCH01000009_gene811	9.929e-30	119.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,2KU8C@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_5351687_1	396588.Tgr7_0328	9.612e-75	256.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1WXHM@135613|Chromatiales	135613|Chromatiales	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
EH2_k127_5351687_0	1123399.AQVE01000024_gene2795	2.278e-169	540.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
EH2_k127_5357402_1	713587.THITH_12295	3.117e-56	199.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1WY7Q@135613|Chromatiales	135613|Chromatiales	S	PFAM Fe-S metabolism associated	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
EH2_k127_5357402_2	572477.Alvin_2667	7.632e-46	168.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales	135613|Chromatiales	S	Belongs to the HesB IscA family	-	-	-	ko:K05997,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH2_k127_5357402_3	1342302.JASC01000014_gene1437	3.091e-36	141.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,3ZXDS@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Iron-sulfur cluster assembly protein	mrp	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
EH2_k127_5357402_0	768671.ThimaDRAFT_1716	1.925e-60	213.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales	135613|Chromatiales	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
EH2_k127_5359661_1	1177179.A11A3_01982	1.955e-131	438.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1XIFC@135619|Oceanospirillales	135619|Oceanospirillales	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
EH2_k127_5359661_0	498211.CJA_3382	1.072e-241	769.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1FG4K@10|Cellvibrio	1236|Gammaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
EH2_k127_5359661_2	391615.ABSJ01000042_gene2254	4.027e-94	313.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1J50S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein, ATPase PilU	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_5363739_0	373994.Riv7116_1951	8.31e-83	280.0	COG0518@1|root,COG0518@2|Bacteria,1G5SC@1117|Cyanobacteria,1HRH1@1161|Nostocales	1117|Cyanobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
EH2_k127_5375770_1	717785.HYPMC_4316	1.888e-06	50.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2TU9T@28211|Alphaproteobacteria,3N6YG@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH2_k127_5375770_0	42099.EPrPV00000020805	9.615e-103	353.0	COG0265@1|root,KOG1421@2759|Eukaryota,1MA90@121069|Pythiales	121069|Pythiales	O	Pro-apoptotic serine protease nma111. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,Trypsin_2
EH2_k127_5377205_1	1177181.T9A_02588	3.659e-95	329.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1XHE3@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0501 Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_5377205_0	396588.Tgr7_1852	6.534e-142	457.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1WW7E@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
EH2_k127_5377205_3	398767.Glov_2516	1.356e-06	51.0	2DFKR@1|root,2ZS8F@2|Bacteria,1RD1S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5396801_2	870187.Thini_2404	1.109e-220	690.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
EH2_k127_5396801_3	1163617.SCD_n01574	2.753e-193	610.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
EH2_k127_5396801_5	1049564.TevJSym_ag00510	2.215e-44	171.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1J4SR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
EH2_k127_5396801_0	519989.ECTPHS_06822	4.628e-276	880.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales	135613|Chromatiales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
EH2_k127_5396801_4	105559.Nwat_0125	5.735e-163	517.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1WW7W@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
EH2_k127_5396801_7	314278.NB231_13011	1.225e-21	95.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1WZR6@135613|Chromatiales	135613|Chromatiales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
EH2_k127_5396801_1	1198452.Jab_2c24400	5.025e-254	793.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2VHJ7@28216|Betaproteobacteria,472E3@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	SpoVR like protein	spoVR2	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
EH2_k127_5396801_6	83406.HDN1F_20760	1.377e-32	128.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1J4X8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0229 family	yeaH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
EH2_k127_5434046_0	396588.Tgr7_1129	3.764e-122	399.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJ6@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_5434046_1	519989.ECTPHS_02851	2.745e-75	263.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1WX31@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
EH2_k127_5434046_2	754477.Q7C_2464	4.913e-08	61.0	2A495@1|root,30SUK@2|Bacteria,1PJZN@1224|Proteobacteria,1SX6T@1236|Gammaproteobacteria,46387@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH2_k127_5434046_3	1485544.JQKP01000002_gene1449	0.0001088	45.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2WCG6@28216|Betaproteobacteria,44W0X@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5447593_2	1384054.N790_09465	1.312e-35	139.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1X3H9@135614|Xanthomonadales	135614|Xanthomonadales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
EH2_k127_5447593_3	1279015.KB908457_gene2404	1.881e-33	132.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1Y5U1@135624|Aeromonadales	135624|Aeromonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
EH2_k127_5447593_0	519989.ECTPHS_01504	2.111e-85	290.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_5447593_1	765913.ThidrDRAFT_3104	2.842e-84	289.0	COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,1WWDI@135613|Chromatiales	135613|Chromatiales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_5464771_9	1123399.AQVE01000009_gene3150	1.547e-13	70.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,45ZQ2@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
EH2_k127_5464771_2	391615.ABSJ01000054_gene1413	1.283e-166	532.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1J4KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082	Iso_dh
EH2_k127_5464771_1	396588.Tgr7_1248	3.203e-184	580.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_5464771_5	396588.Tgr7_1249	9.199e-96	347.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales	135613|Chromatiales	NU	FimV C-terminal	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
EH2_k127_5464771_8	1049564.TevJSym_ac01170	1.271e-22	111.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1J6YG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar hook-length control protein	fliK	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
EH2_k127_5464771_6	1121935.AQXX01000110_gene5498	1.313e-57	205.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1XK82@135619|Oceanospirillales	135619|Oceanospirillales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_5464771_0	1234364.AMSF01000086_gene2807	3.648e-219	698.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X49D@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis protein	cheA1	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH2_k127_5464771_7	857087.Metme_2153	5.665e-47	174.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1XEZV@135618|Methylococcales	135618|Methylococcales	NT	PFAM CheW-like	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_5464771_3	1304883.KI912532_gene179	4.389e-159	533.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_8
EH2_k127_5464771_4	1116472.MGMO_15c00540	1.259e-113	379.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XFKT@135618|Methylococcales	135618|Methylococcales	T	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,PAS_3,PAS_8,PAS_9,TarH
EH2_k127_5474349_0	870187.Thini_3869	6.465e-164	526.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,46016@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
EH2_k127_5474349_1	931627.MycrhDRAFT_3461	2.695e-95	321.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
EH2_k127_5474349_2	931627.MycrhDRAFT_3461	1.603e-20	93.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
EH2_k127_5474349_3	1240350.AMZE01000005_gene2599	4.255e-08	55.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,1RQYV@1236|Gammaproteobacteria,1YVVQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
EH2_k127_5476880_4	187272.Mlg_1907	8.363e-10	60.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WYYA@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
EH2_k127_5476880_3	870187.Thini_4089	3.271e-57	202.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4611H@72273|Thiotrichales	72273|Thiotrichales	I	Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH2_k127_5476880_0	1049564.TevJSym_ac01310	4.808e-193	611.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
EH2_k127_5476880_2	1255043.TVNIR_3161	4.722e-62	218.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
EH2_k127_5476880_1	1123393.KB891328_gene533	4.901e-162	519.0	COG0475@1|root,COG0475@2|Bacteria,1PK6S@1224|Proteobacteria,2VZ60@28216|Betaproteobacteria,1KTFQ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
EH2_k127_5478797_0	1396418.BATQ01000120_gene3082	2.293e-107	360.0	COG1566@1|root,COG1566@2|Bacteria,46VGK@74201|Verrucomicrobia,2IV9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH2_k127_5478797_1	1396418.BATQ01000120_gene3081	7.996e-31	124.0	2CIMK@1|root,32S89@2|Bacteria,46WGT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3302
EH2_k127_5479275_0	349124.Hhal_1109	5.92e-270	848.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales	135613|Chromatiales	F	PFAM glycosyl transferase family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
EH2_k127_5479275_3	1049564.TevJSym_ac01960	2.049e-94	313.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
EH2_k127_5479275_2	1246995.AFR_27055	5.162e-104	361.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DHDF@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_5479275_1	697282.Mettu_1170	4.983e-198	632.0	COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales	135618|Methylococcales	KLT	kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2,Pkinase
EH2_k127_5479275_4	236097.ADG881_1763	3.556e-82	278.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,1XHYM@135619|Oceanospirillales	135619|Oceanospirillales	P	Nitrate nitrite transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
EH2_k127_5485368_1	1049564.TevJSym_ah00860	1.727e-65	228.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria	1224|Proteobacteria	K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002	QueF,QueF_N
EH2_k127_5485368_0	396588.Tgr7_2028	3.967e-148	481.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales	135613|Chromatiales	G	PFAM carbohydrate kinase	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
EH2_k127_5485368_2	1026882.MAMP_01063	3.022e-10	63.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
EH2_k127_5489817_1	765913.ThidrDRAFT_0302	1.498e-117	389.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales	135613|Chromatiales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
EH2_k127_5489817_2	1123518.ARWI01000001_gene2126	9.52e-55	202.0	COG1073@1|root,COG1073@2|Bacteria,1RD2N@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF1749
EH2_k127_5489817_0	1163617.SCD_n00400	8.542e-151	504.0	COG5001@1|root,COG5001@2|Bacteria,1R59J@1224|Proteobacteria,2W00Q@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_5499960_1	870187.Thini_0228	3.06e-68	237.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM aminopeptidase N, Escherichia coli type	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
EH2_k127_5499960_0	472759.Nhal_1407	4.956e-136	447.0	COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,EAL,GGDEF,HATPase_c,HisKA,Hpt,Response_reg
EH2_k127_550081_0	62928.azo1940	3.864e-98	327.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,2KVKV@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
EH2_k127_5504975_1	1122604.JONR01000039_gene3778	1.128e-62	218.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria,1XC99@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_30
EH2_k127_5504975_0	1502852.FG94_00148	8.157e-178	569.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2WENQ@28216|Betaproteobacteria,472E8@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
EH2_k127_5504975_2	1123377.AUIV01000015_gene234	2.353e-48	188.0	COG1413@1|root,COG1413@2|Bacteria,1N7WF@1224|Proteobacteria,1SS5I@1236|Gammaproteobacteria,1XA7X@135614|Xanthomonadales	135614|Xanthomonadales	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
EH2_k127_5504975_3	1166948.JPZL01000001_gene2216	1.839e-36	142.0	COG0745@1|root,COG0745@2|Bacteria,1N8CM@1224|Proteobacteria,1SZK6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_5506288_1	377629.TERTU_4663	8.962e-08	62.0	28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,1RZT6@1236|Gammaproteobacteria,2PNC9@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5506288_0	1123400.KB904765_gene1385	8.738e-161	509.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_553497_0	1049564.TevJSym_ar00340	1.543e-70	260.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,1T3FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_553497_2	357804.Ping_1841	2.223e-09	60.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QIRW@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,EAL,GGDEF,PAS_4,PAS_9
EH2_k127_553497_1	102125.Xen7305DRAFT_00033220	1.68e-42	168.0	COG3452@1|root,COG5002@1|root,COG3452@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_5558388_5	935567.JAES01000012_gene943	0.0008741	42.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH2_k127_5558388_4	1163617.SCD_n00433	1.502e-21	99.0	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,2VXD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5558388_3	1488328.JMCL01000080_gene975	1.607e-34	149.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Thymidine phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_5558388_1	391615.ABSJ01000026_gene100	4.991e-156	510.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1J5DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
EH2_k127_5558388_2	870187.Thini_4186	1.77e-89	303.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,460FP@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
EH2_k127_5558388_0	396588.Tgr7_1282	8.384e-240	753.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
EH2_k127_5565914_1	335283.Neut_1504	3.862e-76	261.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,371ZM@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH2_k127_5565914_0	187272.Mlg_2524	6.542e-108	364.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,1WWJG@135613|Chromatiales	135613|Chromatiales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
EH2_k127_5565914_2	1485544.JQKP01000013_gene1836	1.351e-15	82.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2W5S7@28216|Betaproteobacteria,44WK1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
EH2_k127_5565914_3	1357272.AVEO02000064_gene508	3.135e-15	78.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1Z5PY@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
EH2_k127_5567548_1	156889.Mmc1_3429	7.627e-34	136.0	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,2UCKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
EH2_k127_5567548_2	396588.Tgr7_0597	1.709e-26	113.0	28J26@1|root,2Z8YT@2|Bacteria,1R7S5@1224|Proteobacteria,1RNDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
EH2_k127_5567548_0	999141.GME_15160	3.472e-99	331.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XHB7@135619|Oceanospirillales	135619|Oceanospirillales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
EH2_k127_5569136_1	713586.KB900536_gene2181	2.171e-41	159.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
EH2_k127_5569136_0	1049564.TevJSym_at00460	1.39e-94	318.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1J4JX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH2_k127_5574557_1	1283300.ATXB01000001_gene1335	4.171e-80	272.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1XE01@135618|Methylococcales	135618|Methylococcales	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	-	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
EH2_k127_5574557_2	1120999.JONM01000002_gene896	1.733e-45	177.0	COG3735@1|root,COG3735@2|Bacteria,1Q121@1224|Proteobacteria,2VT43@28216|Betaproteobacteria,2KRFK@206351|Neisseriales	206351|Neisseriales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
EH2_k127_5574557_3	1001585.MDS_1447	2.06e-31	124.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1YDZS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_2002,iYL1228.KPN_01074	Amidohydro_1
EH2_k127_5574557_0	204773.HEAR0229	1.561e-113	371.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,472KX@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH2_k127_5574557_5	697282.Mettu_1675	8.022e-09	64.0	2DRM4@1|root,33C8W@2|Bacteria,1NQ8K@1224|Proteobacteria,1SGVH@1236|Gammaproteobacteria,1XFRG@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5574557_4	1163617.SCD_n00216	1.111e-17	82.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_5581039_0	87626.PTD2_14019	3.333e-139	450.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,2PZVB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
EH2_k127_5581039_1	870187.Thini_4373	3.385e-26	108.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,45ZYU@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH2_k127_559050_1	870187.Thini_3397	3.28e-114	376.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,45ZMS@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
EH2_k127_559050_0	519989.ECTPHS_01869	2.262e-123	408.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
EH2_k127_559050_2	519989.ECTPHS_01864	2.399e-69	240.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
EH2_k127_5593721_2	926550.CLDAP_17040	6.39e-107	369.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
EH2_k127_5593721_5	1230343.CANP01000035_gene2592	1.37e-32	145.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5593721_4	1249627.D779_0443	4.936e-49	179.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1WYNA@135613|Chromatiales	135613|Chromatiales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
EH2_k127_5593721_6	105559.Nwat_0791	1.072e-29	124.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SCZX@1236|Gammaproteobacteria,1WZ3C@135613|Chromatiales	135613|Chromatiales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
EH2_k127_5593721_3	396588.Tgr7_3074	4.767e-56	202.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
EH2_k127_5593721_1	1123401.JHYQ01000002_gene2737	4.956e-177	561.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales	72273|Thiotrichales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
EH2_k127_5593721_7	1323663.AROI01000025_gene1720	2.389e-26	114.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulatory protein recX	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
EH2_k127_5593721_0	391615.ABSJ01000050_gene1144	5.16e-192	603.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1J58G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
EH2_k127_5605958_1	713586.KB900536_gene1899	6.28e-218	693.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1WWBM@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
EH2_k127_5605958_2	1163617.SCD_n01573	1.017e-51	185.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
EH2_k127_5605958_0	1026882.MAMP_02816	7.664e-282	874.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales	72273|Thiotrichales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
EH2_k127_5609047_4	1121904.ARBP01000002_gene7201	9.418e-40	153.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH2_k127_5609047_5	1163617.SCD_n02318	8.514e-07	52.0	2EA5W@1|root,334AS@2|Bacteria,1NFAR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5609047_2	1049564.TevJSym_ao00510	2.989e-112	372.0	COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_5609047_1	395493.BegalDRAFT_1809	9.291e-118	390.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,460G7@72273|Thiotrichales	72273|Thiotrichales	D	AFG1-like ATPase	zapE	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
EH2_k127_5609047_0	396588.Tgr7_1182	5.565e-268	836.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
EH2_k127_5609047_3	1198232.CYCME_1569	9.584e-83	278.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales	72273|Thiotrichales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
EH2_k127_5617119_0	1236542.BALM01000030_gene2015	3.313e-167	531.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,2QAMM@267890|Shewanellaceae	1236|Gammaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
EH2_k127_564086_3	555778.Hneap_2069	5.194e-35	145.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RWW8@1236|Gammaproteobacteria,1X085@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_564086_0	519989.ECTPHS_11717	6.454e-197	621.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1WVUW@135613|Chromatiales	135613|Chromatiales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
EH2_k127_564086_1	1469245.JFBG01000012_gene931	9.019e-87	291.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_564086_2	926550.CLDAP_30490	3.3e-39	153.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
EH2_k127_564086_4	118173.KB235914_gene2346	1.144e-08	62.0	COG1846@1|root,COG1846@2|Bacteria,1G5A0@1117|Cyanobacteria,1HG19@1150|Oscillatoriales	1117|Cyanobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
EH2_k127_5649554_0	864702.OsccyDRAFT_2897	4.594e-79	293.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1H7Q7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_5653975_1	287.DR97_2740	4.033e-153	489.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1YEGU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
EH2_k127_5653975_0	857087.Metme_4549	1.043e-197	638.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1XEGE@135618|Methylococcales	135618|Methylococcales	P	PFAM Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH2_k127_5661687_0	697282.Mettu_0417	4.929e-135	440.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XDQU@135618|Methylococcales	135618|Methylococcales	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
EH2_k127_5661687_1	187272.Mlg_0956	3.033e-92	307.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales	135613|Chromatiales	F	PFAM glycosyl transferase family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
EH2_k127_5670574_0	314278.NB231_06950	1.704e-142	462.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales	135613|Chromatiales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_5672758_1	1167006.UWK_01728	1.692e-18	92.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,42VM6@68525|delta/epsilon subdivisions,2WXFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
EH2_k127_5672758_0	1121035.AUCH01000015_gene2618	4.157e-127	420.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,2KU83@206389|Rhodocyclales	206389|Rhodocyclales	M	HlyD family secretion protein	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
EH2_k127_5672758_2	247634.GPB2148_2736	8.889e-14	72.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1J5FP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
EH2_k127_5679582_5	754476.Q7A_909	1.704e-42	156.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,45ZTF@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH2_k127_5679582_0	1049564.TevJSym_ab02100	1.369e-243	760.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1J4CY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
EH2_k127_5679582_1	1121937.AUHJ01000002_gene3434	8.095e-93	313.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_5679582_2	1049564.TevJSym_al00280	5.59e-74	258.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1J4P0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	HDOD
EH2_k127_5679582_3	1049564.TevJSym_al00280	2.229e-59	215.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1J4P0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	HDOD
EH2_k127_5679582_4	748247.AZKH_2586	2.167e-53	193.0	COG4564@1|root,COG4564@2|Bacteria,1RJP6@1224|Proteobacteria,2WEEN@28216|Betaproteobacteria,2M047@206389|Rhodocyclales	206389|Rhodocyclales	T	Pfam:Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
EH2_k127_5679582_6	1249627.D779_2933	1.983e-05	49.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X0PH@135613|Chromatiales	135613|Chromatiales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
EH2_k127_5685727_0	857087.Metme_3892	1.705e-163	520.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XEG7@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
EH2_k127_5685727_1	1116472.MGMO_15c00150	1.797e-150	483.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XEPK@135618|Methylococcales	135618|Methylococcales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
EH2_k127_5688268_0	1163617.SCD_n01285	3.242e-81	280.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
EH2_k127_5688268_1	1163617.SCD_n01285	8.304e-65	233.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
EH2_k127_569122_3	697282.Mettu_0413	1.019e-173	559.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XEKR@135618|Methylococcales	135618|Methylococcales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
EH2_k127_569122_0	857087.Metme_1513	0.0	1077.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
EH2_k127_569122_1	396588.Tgr7_2073	2.506e-221	691.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
EH2_k127_569122_2	754477.Q7C_1002	5.159e-217	686.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,460CE@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
EH2_k127_569122_4	243233.MCA1473	2.762e-35	139.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XDQU@135618|Methylococcales	135618|Methylococcales	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
EH2_k127_5716150_5	870187.Thini_0556	7.889e-07	50.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
EH2_k127_5716150_2	545276.KB898724_gene1942	2.516e-47	173.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
EH2_k127_5716150_1	1397527.Q670_14195	1.013e-198	627.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1XQZJ@135619|Oceanospirillales	135619|Oceanospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
EH2_k127_5716150_0	396588.Tgr7_2755	2.604e-240	751.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
EH2_k127_5716150_4	1123401.JHYQ01000006_gene11	1.579e-39	150.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,46147@72273|Thiotrichales	72273|Thiotrichales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
EH2_k127_5716150_3	2340.JV46_16440	5.01e-42	160.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,1T211@1236|Gammaproteobacteria,1JB6B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
EH2_k127_5727485_3	765914.ThisiDRAFT_1351	1.813e-61	218.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1WZS4@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
EH2_k127_5727485_4	1122599.AUGR01000006_gene3677	3.644e-49	182.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XJW7@135619|Oceanospirillales	135619|Oceanospirillales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
EH2_k127_5727485_2	396588.Tgr7_2235	7.383e-71	245.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
EH2_k127_5727485_0	2340.JV46_27640	4.511e-166	527.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1J4F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
EH2_k127_5727485_5	857087.Metme_1490	1.159e-42	159.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XFE7@135618|Methylococcales	135618|Methylococcales	S	Tol-Pal system-associated acyl-CoA thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
EH2_k127_5727485_1	745411.B3C1_15632	4.811e-74	256.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1J5QC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	tolQ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
EH2_k127_5727485_6	391615.ABSJ01000030_gene772	6.413e-42	158.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1J6H1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
EH2_k127_5727485_7	765914.ThisiDRAFT_2557	1.857e-16	90.0	COG3064@1|root,COG3064@2|Bacteria,1R7WR@1224|Proteobacteria,1SZ86@1236|Gammaproteobacteria,1WWRY@135613|Chromatiales	135613|Chromatiales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
EH2_k127_5727485_8	406817.XNC1_1420	1.13e-06	52.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	involved in the tonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
EH2_k127_5738509_0	754476.Q7A_2231	9.247e-84	289.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH2_k127_5738509_1	156889.Mmc1_0043	7.957e-68	236.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria	1224|Proteobacteria	E	Murein peptide amidase A	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
EH2_k127_5742729_2	1509403.GW12_16200	6.093e-06	48.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,3NJX6@468|Moraxellaceae	1236|Gammaproteobacteria	Q	ABC transporter	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_5742729_0	697282.Mettu_2350	8.645e-194	632.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XE8W@135618|Methylococcales	135618|Methylococcales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH2_k127_5742729_1	1211112.ALJC01000126_gene4163	3.319e-19	89.0	2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dNA-binding protein	IV02_05780	-	-	-	-	-	-	-	-	-	-	-	PsiE
EH2_k127_5747647_1	1128427.KB904821_gene1138	7.855e-41	162.0	COG2114@1|root,COG2203@1|root,COG3437@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1FZXP@1117|Cyanobacteria,1H71W@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_5747647_0	1005048.CFU_4079	1.147e-149	477.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,472FT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
EH2_k127_5750455_6	1278309.KB907099_gene2929	2.343e-33	132.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,1RQ6X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5750455_1	1278309.KB907099_gene2927	5.078e-92	331.0	COG4105@1|root,COG4571@1|root,COG4105@2|Bacteria,COG4571@2|Bacteria,1QWIQ@1224|Proteobacteria,1S1BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5750455_3	1278309.KB907099_gene2934	2.295e-64	244.0	COG0666@1|root,COG0790@1|root,COG0666@2|Bacteria,COG0790@2|Bacteria,1RBYV@1224|Proteobacteria,1SXEN@1236|Gammaproteobacteria,1XMMQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
EH2_k127_5750455_0	1049564.TevJSym_ar00380	9.528e-157	507.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria,1JAK0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
EH2_k127_5750455_2	236097.ADG881_1332	2.954e-89	301.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XJHU@135619|Oceanospirillales	135619|Oceanospirillales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
EH2_k127_5750455_5	396588.Tgr7_0371	3.299e-46	173.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1WYFK@135613|Chromatiales	135613|Chromatiales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
EH2_k127_5750455_4	572477.Alvin_1910	2.864e-60	213.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
EH2_k127_5751632_10	2340.JV46_19330	5.631e-15	78.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1J559@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
EH2_k127_5751632_7	675812.VHA_002816	2.471e-51	183.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1XX9W@135623|Vibrionales	135623|Vibrionales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
EH2_k127_5751632_9	395493.BegalDRAFT_3331	3.782e-18	87.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,461EZ@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
EH2_k127_5751632_5	572477.Alvin_0981	1.611e-63	223.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1WWSS@135613|Chromatiales	135613|Chromatiales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
EH2_k127_5751632_0	1415778.JQMM01000001_gene1975	8.4e-323	997.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1J4XI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
EH2_k127_5751632_6	396588.Tgr7_1076	1.17e-51	185.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
EH2_k127_5751632_2	519989.ECTPHS_10306	7.251e-89	298.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1WY1A@135613|Chromatiales	135613|Chromatiales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
EH2_k127_5751632_8	396588.Tgr7_1074	5.555e-43	159.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1WYVE@135613|Chromatiales	135613|Chromatiales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
EH2_k127_5751632_1	396588.Tgr7_1073	1.784e-173	559.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
EH2_k127_5751632_4	583345.Mmol_0535	5.919e-68	235.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,2KMVN@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM response regulator receiver	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
EH2_k127_5751632_3	582744.Msip34_0535	5.833e-71	248.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,2KKSE@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_5757911_2	1283284.AZUK01000001_gene387	1.467e-136	437.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1Y3XF@135624|Aeromonadales	135624|Aeromonadales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
EH2_k127_5757911_3	1265503.KB905172_gene412	7.756e-67	229.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,2Q6X5@267889|Colwelliaceae	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055	NifU_N
EH2_k127_5757911_5	272556.CF65_00711	2.439e-47	171.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1Y8WG@135625|Pasteurellales	135625|Pasteurellales	C	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH2_k127_5757911_6	1049564.TevJSym_au00150	1.103e-40	156.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
EH2_k127_5757911_0	396588.Tgr7_2055	4.927e-265	829.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1X01D@135613|Chromatiales	135613|Chromatiales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH2_k127_5757911_4	545276.KB898730_gene1400	2.327e-57	200.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1X16T@135613|Chromatiales	135613|Chromatiales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
EH2_k127_5757911_8	998674.ATTE01000001_gene4333	3.183e-27	112.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S assembly protein IscX	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
EH2_k127_5757911_1	998674.ATTE01000001_gene2065	4.664e-146	473.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
EH2_k127_5757911_7	519989.ECTPHS_12848	1.842e-28	121.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
EH2_k127_5777725_2	1121015.N789_06035	1.615e-105	347.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1SZUB@1236|Gammaproteobacteria,1X3Q8@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_5777725_3	317025.Tcr_0216	1.856e-103	346.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,460GW@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
EH2_k127_5777725_5	391615.ABSJ01000030_gene823	4.963e-54	199.0	COG1309@1|root,COG1309@2|Bacteria,1RA5Z@1224|Proteobacteria,1S3A4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
EH2_k127_5777725_0	1049564.TevJSym_ca00050	5.792e-265	836.0	COG1033@1|root,COG2834@1|root,COG1033@2|Bacteria,COG2834@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J96Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MMPL family	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
EH2_k127_5777725_4	672.VV93_v1c17360	7.824e-94	315.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
EH2_k127_5777725_6	187272.Mlg_2112	4.244e-43	163.0	COG0824@1|root,COG0824@2|Bacteria,1PUGZ@1224|Proteobacteria,1TAK0@1236|Gammaproteobacteria,1X21V@135613|Chromatiales	135613|Chromatiales	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
EH2_k127_5777725_1	2340.JV46_07480	1.152e-116	390.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1J7IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5787628_1	391615.ABSJ01000026_gene121	7.918e-84	289.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5787628_0	391615.ABSJ01000026_gene120	1.963e-223	711.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1J52P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
EH2_k127_5789458_1	936053.I1CKD9	1.395e-122	405.0	COG0265@1|root,KOG1421@2759|Eukaryota,39J7H@33154|Opisthokonta,3P060@4751|Fungi,1GSR9@112252|Fungi incertae sedis	4751|Fungi	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,Trypsin_2
EH2_k127_5789458_3	518766.Rmar_1253	7.538e-59	219.0	COG2715@1|root,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1FISA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
EH2_k127_5789458_2	1089550.ATTH01000001_gene816	5.995e-59	210.0	COG0700@1|root,COG0700@2|Bacteria,4PM62@976|Bacteroidetes,1FJ72@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
EH2_k127_5789458_0	1123400.KB904750_gene698	6.202e-289	930.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
EH2_k127_5798104_1	1123392.AQWL01000006_gene639	1.563e-36	139.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSIU@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_5798104_0	1123392.AQWL01000006_gene638	2.954e-106	353.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KRZ9@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
EH2_k127_5810029_0	519989.ECTPHS_08493	4.15e-149	486.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH2_k127_5810029_1	1123502.AQXD01000001_gene1231	7.09e-09	64.0	COG2825@1|root,COG2825@2|Bacteria,1QBJ0@1224|Proteobacteria,1T74J@1236|Gammaproteobacteria,1X8RT@135614|Xanthomonadales	135614|Xanthomonadales	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
EH2_k127_5816941_0	391615.ABSJ01000035_gene1008	4.262e-210	658.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1J52Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
EH2_k127_5831164_1	1454004.AW11_01602	0.000488	48.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,1KQ65@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
EH2_k127_5831164_0	582744.Msip34_1412	4.383e-148	472.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,2KKEP@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
EH2_k127_5847326_2	1134474.O59_002328	3.476e-99	328.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1FG0P@10|Cellvibrio	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
EH2_k127_5847326_5	1049564.TevJSym_ah00040	7.812e-53	193.0	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1J6HZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	High frequency lysogenization protein HflD homolog	hflD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
EH2_k127_5847326_3	1121124.JNIX01000016_gene2047	2.935e-66	232.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,2KF4E@204458|Caulobacterales	204458|Caulobacterales	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
EH2_k127_5847326_8	349124.Hhal_2347	2.582e-24	111.0	COG0515@1|root,COG0515@2|Bacteria	349124.Hhal_2347|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5847326_7	349124.Hhal_2346	1.319e-31	131.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
EH2_k127_5847326_1	519989.ECTPHS_12983	2.572e-101	339.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	-	-	2.4.2.28,2.4.2.44	ko:K00772,ko:K19696	ko00270,ko01100,map00270,map01100	M00034	R01402,R09668	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
EH2_k127_5847326_4	1120999.JONM01000001_gene1087	1.878e-59	211.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,2KQWS@206351|Neisseriales	206351|Neisseriales	F	Psort location Cytoplasmic, score 9.97	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
EH2_k127_5847326_6	713586.KB900536_gene721	6.937e-36	140.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
EH2_k127_5847326_0	1049564.TevJSym_ah00550	4.559e-143	461.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1J5G8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790	Glyco_hydro_3
EH2_k127_5847326_9	247633.GP2143_16156	1.074e-17	84.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1J6P4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0227)	yqiA	GO:0003674,GO:0003824,GO:0016787,GO:0016788	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
EH2_k127_5856253_0	1123400.KB904753_gene1059	7.11e-153	494.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
EH2_k127_5856253_1	1515746.HR45_01910	1.22e-46	171.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,2QBKB@267890|Shewanellaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
EH2_k127_5867321_0	1212548.B381_19631	8.098e-145	474.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1YZZJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
EH2_k127_5871960_1	1123393.KB891316_gene1590	3.339e-120	392.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,1KSQE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
EH2_k127_5871960_0	1485544.JQKP01000004_gene464	3.498e-202	640.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,44WG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	NMT1-like family	nasF	-	-	ko:K02051,ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
EH2_k127_5880443_4	1510531.JQJJ01000009_gene1054	9.711e-12	65.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,3JUBJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_5880443_0	388051.AUFE01000001_gene2144	5.06e-208	656.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,1KG4U@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_5880443_2	243233.MCA0562	3.805e-30	124.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,1XFCP@135618|Methylococcales	135618|Methylococcales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
EH2_k127_5880443_1	870187.Thini_3621	5.815e-54	193.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,1SEW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5880443_3	1049564.TevJSym_ad00310	9.444e-20	90.0	2E6HP@1|root,3314Y@2|Bacteria,1QGPJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5882383_0	396588.Tgr7_2886	1.855e-135	436.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
EH2_k127_5882383_1	713586.KB900536_gene1678	1.184e-55	202.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1WXWI@135613|Chromatiales	135613|Chromatiales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
EH2_k127_5908481_0	472759.Nhal_0558	3.261e-110	366.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1WY5A@135613|Chromatiales	135613|Chromatiales	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_5908481_4	290397.Adeh_1893	2.567e-16	80.0	2CFNS@1|root,331AJ@2|Bacteria,1NBYG@1224|Proteobacteria,42VZ5@68525|delta/epsilon subdivisions,2WR8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5908481_1	479434.Sthe_0129	2.61e-88	307.0	COG3434@1|root,COG3434@2|Bacteria,2GA08@200795|Chloroflexi,27Y73@189775|Thermomicrobia	189775|Thermomicrobia	T	Diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_5908481_3	713586.KB900536_gene2462	7.635e-22	94.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
EH2_k127_5908481_2	1265503.KB905171_gene580	3.171e-36	138.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,2Q73M@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
EH2_k127_5911577_0	1123400.KB904791_gene62	2.776e-114	371.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
EH2_k127_5911577_1	396588.Tgr7_1832	9.727e-33	132.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales	135613|Chromatiales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_5924000_1	1123401.JHYQ01000005_gene224	1.72e-47	172.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria,463HX@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
EH2_k127_5924000_0	1232683.ADIMK_3005	2.043e-94	313.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4664T@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	ygaD	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
EH2_k127_5924448_2	98439.AJLL01000048_gene2966	4.746e-17	84.0	COG0837@1|root,COG0837@2|Bacteria,1G1TJ@1117|Cyanobacteria,1JI1G@1189|Stigonemataceae	1117|Cyanobacteria	G	Glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
EH2_k127_5924448_1	1283300.ATXB01000001_gene760	3.99e-62	218.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S4VI@1236|Gammaproteobacteria,1XF76@135618|Methylococcales	135618|Methylococcales	O	PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_5924448_3	1244869.H261_01382	1.808e-15	78.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,2JU2T@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
EH2_k127_5924448_0	748247.AZKH_3408	2.75e-130	424.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KURS@206389|Rhodocyclales	206389|Rhodocyclales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
EH2_k127_5924791_2	1163617.SCD_n02018	6.243e-51	185.0	COG1055@1|root,COG1055@2|Bacteria,1PUZK@1224|Proteobacteria,2VKEF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5924791_1	1163617.SCD_n02019	2.248e-54	194.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria	1224|Proteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
EH2_k127_5924791_0	289376.THEYE_A0729	2.624e-161	514.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
EH2_k127_5930759_1	754476.Q7A_1329	6.208e-56	201.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,460TI@72273|Thiotrichales	72273|Thiotrichales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
EH2_k127_5930759_0	396588.Tgr7_3219	7.023e-135	438.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1WXJX@135613|Chromatiales	135613|Chromatiales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
EH2_k127_5947663_2	459495.SPLC1_S550790	7.88e-09	59.0	2AQY2@1|root,31G6Q@2|Bacteria,1GASS@1117|Cyanobacteria,1HDXN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5947663_0	1210884.HG799469_gene14141	3.567e-106	357.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
EH2_k127_5947663_1	395493.BegalDRAFT_2369	5.027e-59	206.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,462WU@72273|Thiotrichales	72273|Thiotrichales	C	PFAM NapC NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
EH2_k127_5949548_5	1123279.ATUS01000003_gene445	2.698e-31	127.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1J6G2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
EH2_k127_5949548_4	187272.Mlg_0894	1.533e-46	171.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1WYP3@135613|Chromatiales	135613|Chromatiales	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_5949548_3	1198232.CYCME_1055	1.513e-51	190.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,4617F@72273|Thiotrichales	72273|Thiotrichales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
EH2_k127_5949548_0	472759.Nhal_2327	5.415e-119	397.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1WW6Q@135613|Chromatiales	135613|Chromatiales	N	basal body rod protein	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
EH2_k127_5949548_2	472759.Nhal_2328	1.529e-73	255.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1WWVR@135613|Chromatiales	135613|Chromatiales	N	TIGRFAM flagellar basal-body rod protein FlgF	-	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_5949548_1	396588.Tgr7_1222	1.108e-115	377.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1WWJ3@135613|Chromatiales	135613|Chromatiales	N	basal body rod protein	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_5976655_3	1249627.D779_2181	5.962e-61	214.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_5976655_5	498211.CJA_1626	8.734e-20	89.0	2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria,1FHQY@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5976655_0	870187.Thini_4353	9.664e-212	665.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
EH2_k127_5976655_2	1026882.MAMP_01625	3.85e-94	313.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,4606Y@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
EH2_k127_5976655_4	1120963.KB894497_gene2245	1.14e-25	112.0	COG2201@1|root,COG2201@2|Bacteria,1QVV6@1224|Proteobacteria,1T2JY@1236|Gammaproteobacteria,2Q5GY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_5976655_1	87626.PTD2_12964	2.142e-134	456.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,2PZXA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3,dCache_1
EH2_k127_5990881_0	713586.KB900536_gene2916	9.783e-83	282.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
EH2_k127_5990881_1	754476.Q7A_1054	3.624e-25	106.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
EH2_k127_6001639_0	1042876.PPS_2181	1.573e-117	385.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,1RPM6@1236|Gammaproteobacteria,1YW08@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
EH2_k127_6001639_1	314278.NB231_01274	2.144e-33	135.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
EH2_k127_6035324_0	2340.JV46_04650	2.545e-118	388.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
EH2_k127_6035324_1	366394.Smed_5571	1.633e-55	206.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,4BCYX@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
EH2_k127_6080818_0	105559.Nwat_0667	7.326e-139	445.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_6080818_1	105559.Nwat_0192	9.252e-88	297.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WYU5@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_6084019_0	76114.ebA3998	4.777e-119	391.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_6084019_1	931627.MycrhDRAFT_3460	3.647e-93	314.0	COG0667@1|root,COG0667@2|Bacteria,2GKW7@201174|Actinobacteria,236X0@1762|Mycobacteriaceae	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
EH2_k127_6084019_2	690597.JH730978_gene5157	1.566e-24	106.0	COG0665@1|root,COG0665@2|Bacteria,1Q8AY@1224|Proteobacteria,1RSC9@1236|Gammaproteobacteria,1YPPE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
EH2_k127_6091908_1	693444.D782_0740	1.96e-25	110.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,283B9@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
EH2_k127_6091908_0	243233.MCA1077	3.231e-138	443.0	COG2022@1|root,COG2104@1|root,COG2022@2|Bacteria,COG2104@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1XDXA@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
EH2_k127_6091908_2	232346.JHQL01000002_gene1265	1.073e-18	91.0	COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1XMMM@135619|Oceanospirillales	135619|Oceanospirillales	H	COG2104 Sulfur transfer protein involved in thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
EH2_k127_614006_3	472759.Nhal_0011	2.055e-130	424.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1WXJM@135613|Chromatiales	135613|Chromatiales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
EH2_k127_614006_5	1005395.CSV86_25429	2.158e-37	146.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1YV9E@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1722)	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
EH2_k127_614006_2	1123401.JHYQ01000008_gene374	2.271e-144	466.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,45ZRJ@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
EH2_k127_614006_1	395493.BegalDRAFT_3434	1.292e-153	495.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
EH2_k127_614006_4	395493.BegalDRAFT_3435	1.617e-47	172.0	COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SA8D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADP transhydrogenase	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
EH2_k127_614006_0	395493.BegalDRAFT_3436	1.88e-199	631.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
EH2_k127_614006_6	907348.TresaDRAFT_0338	1.476e-05	48.0	COG0457@1|root,COG0457@2|Bacteria,2J5I5@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
EH2_k127_6163407_0	519989.ECTPHS_02821	1.127e-42	157.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
EH2_k127_6163407_2	2340.JV46_20870	1.097e-29	121.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1J6XM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
EH2_k127_6163407_3	696747.NIES39_G00920	7.917e-10	63.0	2AQY2@1|root,31G6Q@2|Bacteria,1GASS@1117|Cyanobacteria,1HDXN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6163407_1	1123487.KB892857_gene2359	2.452e-35	138.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria,2KYYM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6171361_0	1049564.TevJSym_ag00670	3.968e-140	450.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1JB5W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CbbQ/NirQ/NorQ C-terminal	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
EH2_k127_6171361_1	765911.Thivi_2455	9.444e-21	97.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1WXVP@135613|Chromatiales	135613|Chromatiales	P	PFAM von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
EH2_k127_617499_0	1283300.ATXB01000001_gene2077	3.481e-172	553.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1XED7@135618|Methylococcales	135618|Methylococcales	HJ	PFAM ATP-grasp fold	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
EH2_k127_617499_1	314345.SPV1_12627	9.382e-74	256.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
EH2_k127_6187561_4	1046627.BZARG_610	0.0002185	50.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_24
EH2_k127_6187561_0	1141663.OOC_06762	2.009e-77	265.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,3Z888@586|Providencia	1236|Gammaproteobacteria	S	Methyltransferase, YaeB family	yaeB	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	UPF0066
EH2_k127_6187561_2	1122201.AUAZ01000009_gene2848	3.376e-69	240.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	2OG-Fe(II) oxygenase	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
EH2_k127_6187561_1	243231.GSU0462	1.103e-75	265.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,42TCQ@68525|delta/epsilon subdivisions,2WM2D@28221|Deltaproteobacteria,43S2X@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_6187561_3	1049564.TevJSym_bm00060	8.043e-24	106.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria,1J6JD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF898)	yjgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF898
EH2_k127_6209455_2	768706.Desor_4030	9.101e-70	253.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9
EH2_k127_6209455_4	864051.BurJ1DRAFT_0534	8.741e-59	214.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,2VX13@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
EH2_k127_6209455_0	717774.Marme_2938	1.056e-102	352.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,1XHI3@135619|Oceanospirillales	135619|Oceanospirillales	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
EH2_k127_6209455_6	1415780.JPOG01000001_gene3226	9.972e-18	85.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1X8IM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
EH2_k127_6209455_5	3988.XP_002536756.1	5.283e-43	162.0	2BGJX@1|root,2S19K@2759|Eukaryota,380MM@33090|Viridiplantae	33090|Viridiplantae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
EH2_k127_6209455_1	1123368.AUIS01000019_gene1207	4.071e-89	298.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,2NCT4@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_6209455_3	1123368.AUIS01000019_gene1206	7.03e-69	246.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,2NCE0@225057|Acidithiobacillales	225057|Acidithiobacillales	T	His Kinase A (phospho-acceptor) domain	-	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_623552_0	396588.Tgr7_2279	8.6e-173	548.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH2_k127_6275249_1	1000565.METUNv1_02412	1.791e-64	224.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUQA@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
EH2_k127_6275249_0	203122.Sde_1346	1.599e-126	417.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,464EE@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretory pathway, component PulF	-	-	-	ko:K02505,ko:K02653,ko:K12278	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
EH2_k127_6275249_2	1349767.GJA_2105	1.511e-36	151.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_627808_3	558884.JRGM01000135_gene1168	8.652e-11	64.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SYSF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF Domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE5,dCache_1
EH2_k127_627808_2	754476.Q7A_2266	1.042e-55	197.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,460PH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
EH2_k127_627808_1	519989.ECTPHS_00330	1.875e-96	323.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
EH2_k127_627808_0	118005.AWNK01000003_gene2230	0.0	1082.0	COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria	2|Bacteria	G	chondroitin AC lyase activity	ndvB	-	2.4.1.12,3.2.1.58	ko:K00694,ko:K01210,ko:K03292	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R00308,R02889,R03115	RC00005,RC00467	ko00000,ko00001,ko01000,ko01003,ko02000	2.A.2,4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_hydro_17,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,MFS_2
EH2_k127_6305889_1	1211114.ALIP01000095_gene423	4.785e-21	101.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,1X6AA@135614|Xanthomonadales	135614|Xanthomonadales	T	ANTAR	nasT	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
EH2_k127_6305889_0	1232683.ADIMK_2546	4.264e-56	200.0	COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
EH2_k127_6307263_3	1207076.ALAT01000175_gene2098	3.686e-35	151.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,1Z280@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_6307263_6	1523503.JPMY01000041_gene447	5.132e-08	61.0	2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH2_k127_6307263_0	1123393.KB891330_gene893	6.383e-244	761.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1KRHZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
EH2_k127_6307263_2	713586.KB900536_gene1995	4.567e-58	202.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1WY86@135613|Chromatiales	135613|Chromatiales	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
EH2_k127_6307263_4	28229.ND2E_4017	1.802e-33	137.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,2Q743@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
EH2_k127_6307263_5	1123401.JHYQ01000013_gene615	1.44e-16	81.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,461BQ@72273|Thiotrichales	72273|Thiotrichales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
EH2_k127_6307263_1	765913.ThidrDRAFT_0176	1.64e-77	265.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
EH2_k127_6316599_0	1123399.AQVE01000013_gene303	4.772e-188	592.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,45ZNY@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
EH2_k127_6316599_2	349521.HCH_03714	6.425e-40	162.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
EH2_k127_6316599_1	1123399.AQVE01000009_gene3083	2.685e-114	376.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,45ZV3@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
EH2_k127_6316599_3	1123368.AUIS01000003_gene1572	8.451e-18	94.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
EH2_k127_6318399_0	1123228.AUIH01000007_gene2520	1.583e-54	198.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
EH2_k127_6318399_1	1122197.ATWI01000014_gene15	1.719e-31	126.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,467XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
EH2_k127_6325519_0	472759.Nhal_3943	1.574e-253	794.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
EH2_k127_6325519_1	1123261.AXDW01000018_gene768	4.134e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
EH2_k127_6325519_2	1415779.JOMH01000001_gene42	8.566e-17	81.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria,1X4JF@135614|Xanthomonadales	135614|Xanthomonadales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
EH2_k127_6338880_1	323848.Nmul_A2671	2.322e-33	135.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,372BD@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	atoC	-	-	ko:K02481,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_6338880_0	1123393.KB891331_gene2871	4.831e-161	524.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria,1KSG9@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
EH2_k127_6371301_2	713586.KB900536_gene1089	2.712e-110	364.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales	135613|Chromatiales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
EH2_k127_6371301_1	396588.Tgr7_2270	3.564e-129	455.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
EH2_k127_6371301_0	713587.THITH_02750	1.462e-211	667.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
EH2_k127_6371301_4	322710.Avin_12680	1.135e-24	105.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	maF-like protein	yhdE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH2_k127_6372935_0	396588.Tgr7_1003	7.851e-273	861.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
EH2_k127_6372935_4	545276.KB898724_gene1877	2.523e-31	127.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
EH2_k127_6372935_2	2340.JV46_20640	1.843e-115	379.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1J4X5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
EH2_k127_6372935_3	1033802.SSPSH_002381	7.966e-33	130.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
EH2_k127_6372935_1	396588.Tgr7_1007	1.706e-222	699.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
EH2_k127_6373251_11	4533.OB09G24480.1	7.859e-09	57.0	COG0169@1|root,KOG0692@2759|Eukaryota,37S9N@33090|Viridiplantae,3GFW7@35493|Streptophyta,3KMZK@4447|Liliopsida,3ICTK@38820|Poales	35493|Streptophyta	E	3-dehydroquinate synthase	-	GO:0003674,GO:0003824,GO:0003856,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0012505,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019632,GO:0019752,GO:0031410,GO:0031982,GO:0031984,GO:0032787,GO:0033587,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044431,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:0097708,GO:0098791,GO:1901576,GO:1901615,GO:1901617	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH2_k127_6373251_3	713586.KB900536_gene1839	9.22e-157	503.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
EH2_k127_6373251_8	396588.Tgr7_3032	1.032e-32	145.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division protein DamX	damX	GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
EH2_k127_6373251_0	314230.DSM3645_15695	0.0	2186.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2IXKD@203682|Planctomycetes	203682|Planctomycetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
EH2_k127_6373251_1	530564.Psta_0200	4.582e-224	702.0	COG0493@1|root,COG0493@2|Bacteria,2IXFM@203682|Planctomycetes	203682|Planctomycetes	C	COG0493 NADPH-dependent glutamate synthase beta chain and	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
EH2_k127_6373251_10	1255043.TVNIR_2480	6.999e-15	78.0	2EJPI@1|root,33DEC@2|Bacteria,1NM06@1224|Proteobacteria,1SHXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6373251_6	237609.PSAKL28_41940	7.959e-44	162.0	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11022	ko05134,map05134	-	-	-	ko00000,ko00001,ko02042	-	-	-	-
EH2_k127_6373251_7	2340.JV46_24450	5.131e-42	158.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_6373251_5	1397527.Q670_05200	9.129e-70	238.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
EH2_k127_6373251_2	396588.Tgr7_0953	2.311e-167	544.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1WXD7@135613|Chromatiales	135613|Chromatiales	M	lytic transglycosylase	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
EH2_k127_6373251_4	391615.ABSJ01000026_gene110	3.126e-105	353.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
EH2_k127_6373251_9	1173263.Syn7502_01309	8.862e-20	89.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1G34C@1117|Cyanobacteria,1H0B4@1129|Synechococcus	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
EH2_k127_6374866_2	768671.ThimaDRAFT_3356	2.575e-58	207.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales	135613|Chromatiales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
EH2_k127_6374866_3	1163617.SCD_n02062	9.021e-24	104.0	COG2920@1|root,COG2920@2|Bacteria,1NAQC@1224|Proteobacteria,2VWA3@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_6374866_0	754477.Q7C_610	3.688e-106	351.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,4607M@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
EH2_k127_6374866_4	754477.Q7C_1686	3.128e-11	74.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1QYKR@1224|Proteobacteria,1T3X5@1236|Gammaproteobacteria,460SR@72273|Thiotrichales	72273|Thiotrichales	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
EH2_k127_6374866_1	1049564.TevJSym_aa00850	2.091e-61	216.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J4H6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
EH2_k127_6384860_0	1026882.MAMP_00158	5.088e-156	504.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_6384860_2	414684.RC1_3303	3.266e-53	195.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U7TT@28211|Alphaproteobacteria,2JWI6@204441|Rhodospirillales	204441|Rhodospirillales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
EH2_k127_6384860_1	1094715.CM001373_gene2170	5.989e-72	248.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,1S2QF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
EH2_k127_6384860_3	1168067.JAGP01000001_gene1890	3.577e-25	107.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,460S7@72273|Thiotrichales	72273|Thiotrichales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
EH2_k127_6386475_0	1168065.DOK_13774	0.0	1116.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1J4ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
EH2_k127_6392202_2	393595.ABO_1909	2.009e-79	275.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1XHE3@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0501 Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_6392202_3	1121935.AQXX01000097_gene1733	5.033e-65	227.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1XI0A@135619|Oceanospirillales	135619|Oceanospirillales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
EH2_k127_6392202_4	1177181.T9A_01313	2.98e-42	158.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1XKKD@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0784 FOG CheY-like receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_6392202_5	29581.BW37_05349	4.723e-22	104.0	2CEXV@1|root,32S0S@2|Bacteria,1MZKB@1224|Proteobacteria,2VU8J@28216|Betaproteobacteria,474XU@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Type II secretion system protein B	gspB	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
EH2_k127_6392202_0	745411.B3C1_05872	2.559e-150	492.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1J4NA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretory pathway component ExeA	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
EH2_k127_6392202_1	768671.ThimaDRAFT_4620	1.234e-87	296.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1WVUJ@135613|Chromatiales	135613|Chromatiales	C	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
EH2_k127_6397153_4	1304888.ATWF01000001_gene627	6.773e-99	343.0	COG3087@1|root,COG3087@2|Bacteria,2GF99@200930|Deferribacteres	200930|Deferribacteres	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6397153_8	1163617.SCD_n01157	5.86e-36	141.0	COG3439@1|root,COG3439@2|Bacteria,1N4Z5@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_6397153_1	1163617.SCD_n01153	3.102e-239	744.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_6397153_2	1163617.SCD_n01152	4.336e-182	575.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_6397153_0	1163617.SCD_n01151	3.092e-299	923.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
EH2_k127_6397153_3	1163617.SCD_n01150	1.984e-120	388.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH2_k127_6397153_10	1163617.SCD_n00747	1.057e-25	112.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,2VVCA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6397153_5	1163617.SCD_n01145	3.758e-75	262.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
EH2_k127_6397153_9	1049564.TevJSym_bv00040	2.419e-34	143.0	COG1463@1|root,COG1463@2|Bacteria,1NP1A@1224|Proteobacteria	1224|Proteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH2_k127_6397153_11	693986.MOC_2365	1.555e-07	61.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,1JR4C@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM ABC transporter	yrbF	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH2_k127_6397153_7	1049564.TevJSym_bv00020	1.124e-50	187.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
EH2_k127_6400303_1	1123393.KB891316_gene1260	5.166e-93	315.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KSYR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH2_k127_6400303_3	1121921.KB898709_gene289	1.345e-05	52.0	2ERWY@1|root,33JG3@2|Bacteria,1NIZY@1224|Proteobacteria,1SH96@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
EH2_k127_6400303_0	1049564.TevJSym_ab00760	5.316e-150	486.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	DNA Recombination protein RmuC	rmuC	GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
EH2_k127_6400303_2	1168065.DOK_14679	3.338e-32	129.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,1J71Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
EH2_k127_6402270_0	870187.Thini_1586	1.984e-85	291.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,460B1@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
EH2_k127_6402455_1	713586.KB900536_gene3046	1.254e-100	328.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
EH2_k127_6402455_3	713586.KB900536_gene3045	2.788e-87	295.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
EH2_k127_6402455_2	1123400.KB904758_gene2396	1.603e-98	325.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,46002@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
EH2_k127_6402455_0	1453503.AU05_07450	7.155e-200	667.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE8V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
EH2_k127_6402455_6	202954.BBNK01000003_gene2690	7.774e-05	45.0	2A3SE@1|root,30SAA@2|Bacteria,1QQHN@1224|Proteobacteria,1RT5P@1236|Gammaproteobacteria,3NS9N@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6402455_5	1049564.TevJSym_ap00640	1.296e-21	98.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1J6XI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Preprotein translocase subunit SecG	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
EH2_k127_6402455_4	396588.Tgr7_0984	1.153e-69	238.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales	135613|Chromatiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
EH2_k127_640353_1	187272.Mlg_1950	1.212e-43	166.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1WY8Z@135613|Chromatiales	135613|Chromatiales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
EH2_k127_640353_0	713586.KB900536_gene3059	1.028e-222	700.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
EH2_k127_640353_2	1121374.KB891586_gene2704	1.101e-10	63.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
EH2_k127_6410951_2	391615.ABSJ01000026_gene145	1.715e-104	346.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1J513@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH2_k127_6410951_4	391615.ABSJ01000026_gene144	6.842e-78	264.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1J5ZJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
EH2_k127_6410951_3	395493.BegalDRAFT_3263	8.612e-101	334.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
EH2_k127_6410951_5	1122599.AUGR01000001_gene430	2.473e-49	186.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1XJNR@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
EH2_k127_6410951_0	396588.Tgr7_1165	1.657e-162	522.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1WX71@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
EH2_k127_6410951_1	713586.KB900536_gene134	4.816e-135	444.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales	135613|Chromatiales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
EH2_k127_6410951_6	1123377.AUIV01000010_gene2212	1.075e-12	70.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH2_k127_6411598_0	322710.Avin_25830	4.241e-83	286.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF family	xdhC2	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
EH2_k127_6411598_1	1123393.KB891332_gene2832	3.683e-49	181.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria,1KRTP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
EH2_k127_6419361_0	1049564.TevJSym_ap00510	5.355e-177	562.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1J4U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341,ko:K05559	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
EH2_k127_6427989_0	1049564.TevJSym_ag00460	1.457e-104	343.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	HAD-hyrolase-like	gph	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756	HAD_2
EH2_k127_6427989_1	1278309.KB907107_gene1642	1.558e-32	127.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBT@135619|Oceanospirillales	135619|Oceanospirillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_644515_0	105559.Nwat_2226	1.434e-149	480.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1WXH7@135613|Chromatiales	135613|Chromatiales	I	SMART Phospholipid glycerol acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
EH2_k127_6446060_1	713586.KB900536_gene991	4.432e-143	458.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
EH2_k127_6446060_2	765912.Thimo_3362	5.452e-72	252.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
EH2_k127_6446060_4	1121013.P873_07510	2.571e-44	166.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
EH2_k127_6446060_0	519989.ECTPHS_00590	4.781e-279	864.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
EH2_k127_6454976_0	396588.Tgr7_1853	3.862e-139	449.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	135613|Chromatiales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
EH2_k127_6454976_1	1122194.AUHU01000002_gene2545	6.237e-55	201.0	COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,467WD@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
EH2_k127_6454976_2	396588.Tgr7_0508	1.568e-48	181.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_6454976_3	349521.HCH_00586	5.56e-19	96.0	29QWA@1|root,30BWM@2|Bacteria,1REIR@1224|Proteobacteria,1S50N@1236|Gammaproteobacteria,1XQ5R@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6455603_1	697282.Mettu_3269	1.591e-23	114.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XDJQ@135618|Methylococcales	135618|Methylococcales	F	PFAM Adenylate cyclase, class-I	-	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
EH2_k127_6455603_0	522306.CAP2UW1_3214	5.629e-206	646.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6460003_1	157783.LK03_09325	2.333e-87	296.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
EH2_k127_6460003_0	870187.Thini_1102	1.097e-169	539.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH2_k127_6460003_2	1163408.UU9_16893	7.473e-12	67.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1X4P8@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
EH2_k127_6477189_0	396588.Tgr7_2279	6.766e-156	498.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH2_k127_6477189_3	519989.ECTPHS_03031	5.338e-23	105.0	COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales	135613|Chromatiales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
EH2_k127_6477189_2	396588.Tgr7_2277	8.816e-102	342.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
EH2_k127_6477189_1	1298593.TOL_3480	2.396e-131	426.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XHW9@135619|Oceanospirillales	135619|Oceanospirillales	G	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.4,2.7.1.73	ko:K00847,ko:K00892	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00760,R00867,R01131,R01228,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
EH2_k127_6484953_0	870187.Thini_0474	6.215e-165	528.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,46028@72273|Thiotrichales	72273|Thiotrichales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH2_k127_6484953_1	1123399.AQVE01000020_gene1700	9.49e-97	319.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH2_k127_6496720_0	1411123.JQNH01000001_gene3657	2e-321	998.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
EH2_k127_6496720_1	1280944.HY17_09955	3.495e-19	87.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,43XEI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	MA20_17490	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
EH2_k127_650273_10	765913.ThidrDRAFT_2949	3.847e-09	60.0	2E181@1|root,32WNM@2|Bacteria,1N2P2@1224|Proteobacteria,1SARH@1236|Gammaproteobacteria,1WYZE@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
EH2_k127_650273_9	519989.ECTPHS_05040	3.531e-34	138.0	COG3151@1|root,COG3151@2|Bacteria,1NAPI@1224|Proteobacteria,1SEY8@1236|Gammaproteobacteria,1WYT2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1249)	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
EH2_k127_650273_0	519989.ECTPHS_08231	0.0	1286.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH2_k127_650273_2	572477.Alvin_1986	7.122e-172	545.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
EH2_k127_650273_3	555778.Hneap_1337	4.481e-153	493.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales	135613|Chromatiales	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH2_k127_650273_5	1049564.TevJSym_ad01430	2.792e-132	431.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1J4I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
EH2_k127_650273_4	765914.ThisiDRAFT_0792	1.614e-143	464.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WXIX@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_650273_6	631362.Thi970DRAFT_04861	6.615e-101	336.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales	135613|Chromatiales	E	PFAM Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
EH2_k127_650273_1	870187.Thini_0762	2.237e-201	635.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46046@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
EH2_k127_650273_7	1298593.TOL_2285	1.67e-75	259.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1XJAC@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
EH2_k127_650273_8	349521.HCH_04978	2.192e-46	170.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWP@135619|Oceanospirillales	135619|Oceanospirillales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
EH2_k127_6523209_3	2340.JV46_24740	3.663e-98	327.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
EH2_k127_6523209_1	1049564.TevJSym_aw00060	3.622e-106	355.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	dsrS	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6523209_7	1121374.KB891586_gene2531	1.189e-16	88.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
EH2_k127_6523209_0	396588.Tgr7_1114	6.975e-240	755.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,Response_reg
EH2_k127_6523209_6	857087.Metme_3902	2.606e-68	235.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1T3Z8@1236|Gammaproteobacteria,1XGIJ@135618|Methylococcales	135618|Methylococcales	T	SMART Signal transduction response regulator, receiver region	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_6523209_4	589865.DaAHT2_1362	6.56e-85	297.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WJRA@28221|Deltaproteobacteria,2MKMD@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA
EH2_k127_6523209_5	580332.Slit_1183	9.04e-73	255.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,44WNG@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_6523209_2	857087.Metme_3901	1.158e-98	336.0	COG2202@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
EH2_k127_65309_0	713586.KB900536_gene2551	1.289e-54	206.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales	135613|Chromatiales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_65309_1	1249627.D779_2181	4.328e-52	186.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_6550407_0	1049564.TevJSym_bb00110	1.391e-182	574.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1J4ZB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the citrate synthase family	gltA	GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_00727	Citrate_synt
EH2_k127_6550407_2	1304883.KI912532_gene1806	1.007e-33	134.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,2KWZ1@206389|Rhodocyclales	206389|Rhodocyclales	S	Invasion gene expression up-regulator SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
EH2_k127_6550407_1	572477.Alvin_1989	4.284e-130	424.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1WWQU@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
EH2_k127_6550407_3	349124.Hhal_1830	3.132e-30	128.0	COG0136@1|root,335ZB@2|Bacteria,1NQEQ@1224|Proteobacteria,1SI1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
EH2_k127_6565645_0	1469245.JFBG01000027_gene1443	8.115e-33	134.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
EH2_k127_6566268_1	1298593.TOL_3135	3.413e-91	309.0	COG3290@1|root,COG5001@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	morA	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_2
EH2_k127_6566268_0	713586.KB900536_gene2880	0.0	1010.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_6574989_3	765913.ThidrDRAFT_0176	1.591e-30	122.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
EH2_k127_6574989_0	870187.Thini_2861	1.804e-130	424.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,4603K@72273|Thiotrichales	72273|Thiotrichales	O	magnesium chelatase	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
EH2_k127_6574989_6	1150469.RSPPHO_02782	0.0002643	43.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K10297	-	-	-	-	ko00000,ko04121	-	-	-	Beta_helix,SLH,TIR_2
EH2_k127_6574989_1	1485545.JQLW01000009_gene194	9.576e-127	421.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Fer4_9,PK,PK_C
EH2_k127_6574989_4	234267.Acid_7925	1.088e-22	105.0	COG3832@1|root,COG3832@2|Bacteria,3Y94H@57723|Acidobacteria	57723|Acidobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6574989_2	768671.ThimaDRAFT_4313	1.034e-32	133.0	2DTFC@1|root,33K4P@2|Bacteria,1PWJK@1224|Proteobacteria,1SJ8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6574989_5	247633.GP2143_00962	4.626e-05	46.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1J535@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
EH2_k127_6589850_0	187272.Mlg_0061	4.862e-57	201.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
EH2_k127_6589850_1	713586.KB900536_gene2181	5.285e-45	171.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
EH2_k127_6589850_2	930166.CD58_28685	7.545e-10	60.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH2_k127_6592383_4	1163617.SCD_n00988	6.173e-63	218.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria	28216|Betaproteobacteria	G	deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
EH2_k127_6592383_1	396588.Tgr7_3071	8.054e-140	454.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1WWVD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
EH2_k127_6592383_3	395494.Galf_0627	8.341e-98	325.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VKFG@28216|Betaproteobacteria,44VP1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
EH2_k127_6592383_0	1049564.TevJSym_au00630	2.49e-258	803.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
EH2_k127_6592383_2	1049564.TevJSym_au00640	1.223e-104	344.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
EH2_k127_6592383_5	765911.Thivi_1045	9.603e-19	87.0	2E5UC@1|root,330IN@2|Bacteria,1NAMZ@1224|Proteobacteria,1SCK7@1236|Gammaproteobacteria,1WZB2@135613|Chromatiales	135613|Chromatiales	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
EH2_k127_6601666_2	1121374.KB891575_gene1097	7.999e-30	121.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
EH2_k127_6601666_3	498211.CJA_3266	4.328e-23	100.0	2AU9U@1|root,31JXA@2|Bacteria,1QHQS@1224|Proteobacteria,1TFEW@1236|Gammaproteobacteria,1FHNB@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
EH2_k127_6601666_0	1117647.M5M_12200	3.688e-56	201.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
EH2_k127_6601666_1	1397527.Q670_00110	1.363e-31	126.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1XP8B@135619|Oceanospirillales	135619|Oceanospirillales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
EH2_k127_6611886_4	626887.J057_03430	3.762e-18	88.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,466ER@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
EH2_k127_6611886_1	765914.ThisiDRAFT_2170	7.828e-111	371.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,1WW8E@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
EH2_k127_6611886_2	768671.ThimaDRAFT_0820	1.063e-90	302.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria,1WWZ5@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_6611886_0	697282.Mettu_2124	7.596e-148	472.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XEXJ@135618|Methylococcales	135618|Methylococcales	K	PFAM HTH transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_6611886_3	396588.Tgr7_2456	5.275e-63	220.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH2_k127_6616066_1	1430440.MGMSRv2_1583	2.437e-181	581.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,2JQXB@204441|Rhodospirillales	204441|Rhodospirillales	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
EH2_k127_6616066_2	1117318.PRUB_13986	1.365e-69	243.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,2Q1AT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
EH2_k127_6616066_0	393595.ABO_0046	3.067e-263	827.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XI15@135619|Oceanospirillales	135619|Oceanospirillales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
EH2_k127_66381_2	1168065.DOK_19165	6.83e-39	165.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1J501@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Adenylate cyclase	cyaA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365	Adenyl_cycl_N,Adenylate_cycl
EH2_k127_66381_4	335541.Swol_2441	5.066e-21	102.0	COG0745@1|root,COG0745@2|Bacteria	335541.Swol_2441|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_66381_0	1123401.JHYQ01000002_gene2583	2.644e-122	404.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
EH2_k127_66381_3	1448139.AI20_03355	2.181e-38	159.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y4B8@135624|Aeromonadales	135624|Aeromonadales	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
EH2_k127_66381_5	1304883.KI912532_gene1960	9.591e-06	56.0	2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,2KYBI@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_66381_1	243233.MCA1408	1.136e-82	285.0	COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,1XG4U@135618|Methylococcales	135618|Methylococcales	S	COG4240 Predicted kinase	-	-	2.7.1.31	ko:K15918	ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
EH2_k127_6657369_2	1485544.JQKP01000002_gene1341	1.028e-146	474.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,44VHX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
EH2_k127_6657369_6	754476.Q7A_1345	3.697e-16	80.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1RTX4@1236|Gammaproteobacteria,461HH@72273|Thiotrichales	72273|Thiotrichales	P	cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
EH2_k127_6657369_3	1123228.AUIH01000008_gene2428	7.522e-95	328.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_6657369_0	1221522.B723_16310	7.338e-305	943.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1YS5T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_6657369_1	1123399.AQVE01000001_gene481	8.532e-157	498.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,4606J@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
EH2_k127_6657369_4	572477.Alvin_0442	4.578e-40	160.0	2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,1RQ0D@1236|Gammaproteobacteria,1X2KV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6657369_5	765911.Thivi_4158	1.709e-31	130.0	28P01@1|root,2ZBWR@2|Bacteria,1RB5K@1224|Proteobacteria,1S2PB@1236|Gammaproteobacteria,1WXYS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6676142_0	187272.Mlg_2392	1.266e-112	372.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
EH2_k127_6683887_0	292415.Tbd_1500	0.0	1159.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Inorganic H+ pyrophosphatase	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
EH2_k127_6683887_2	765911.Thivi_3380	2.486e-16	81.0	2ESIQ@1|root,33K3E@2|Bacteria,1NJ20@1224|Proteobacteria,1SVD6@1236|Gammaproteobacteria,1X1VD@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6683887_1	292415.Tbd_1502	7.516e-133	424.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
EH2_k127_6689485_1	1537994.JQFW01000015_gene1501	9.652e-13	72.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,466UM@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
EH2_k127_6689485_0	83406.HDN1F_21820	6.995e-109	357.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
EH2_k127_6698718_2	105559.Nwat_0026	4.618e-35	143.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
EH2_k127_6698718_0	1249627.D779_3818	4.028e-116	380.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
EH2_k127_6698718_1	1123392.AQWL01000005_gene3076	8.03e-66	226.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nadh flavin oxidoreductase nadh oxidase	nemA	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
EH2_k127_6702531_0	765914.ThisiDRAFT_0316	9.152e-131	426.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WXNQ@135613|Chromatiales	135613|Chromatiales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_6702531_1	1116472.MGMO_25c00370	2.952e-79	271.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1XEGP@135618|Methylococcales	135618|Methylococcales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
EH2_k127_6702531_2	90813.JQMT01000001_gene1276	9.006e-50	181.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales	72273|Thiotrichales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH2_k127_6703162_2	697282.Mettu_2434	1.118e-16	90.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XDJQ@135618|Methylococcales	135618|Methylococcales	F	PFAM Adenylate cyclase, class-I	-	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
EH2_k127_6703162_1	1123368.AUIS01000006_gene590	1.336e-58	209.0	2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,1SJ45@1236|Gammaproteobacteria,2NCXG@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6703162_0	765914.ThisiDRAFT_0009	6.084e-161	514.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH2_k127_6705659_2	930169.B5T_00847	2.145e-29	126.0	COG4585@1|root,COG4585@2|Bacteria,1QSUV@1224|Proteobacteria,1RR41@1236|Gammaproteobacteria,1XNEI@135619|Oceanospirillales	135619|Oceanospirillales	T	COG4585 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6705659_1	396588.Tgr7_0262	8.649e-32	132.0	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SWTF@1236|Gammaproteobacteria,1WZTX@135613|Chromatiales	135613|Chromatiales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH2_k127_6705659_0	519989.ECTPHS_12617	8.899e-54	191.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales	135613|Chromatiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
EH2_k127_6725123_0	1163617.SCD_n01694	1.31e-47	192.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,2VM4I@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-associated protein 3	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
EH2_k127_6730249_1	870187.Thini_3392	3.559e-91	312.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,45ZR1@72273|Thiotrichales	72273|Thiotrichales	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_6730249_0	396588.Tgr7_0763	3.93e-191	612.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
EH2_k127_6730249_2	396588.Tgr7_0762	3.133e-18	88.0	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
EH2_k127_6731413_2	1116472.MGMO_122c00070	4.68e-59	207.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XENU@135618|Methylococcales	135618|Methylococcales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH2_k127_6731413_5	1158760.AQXP01000049_gene593	3.733e-19	91.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1WZKP@135613|Chromatiales	135613|Chromatiales	S	YcgL domain	-	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
EH2_k127_6731413_3	1042375.AFPL01000008_gene3315	2.869e-31	127.0	COG1278@1|root,COG1278@2|Bacteria,1N0MM@1224|Proteobacteria,1S8XG@1236|Gammaproteobacteria,468TP@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_6731413_4	1123279.ATUS01000001_gene1053	1.068e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1J6MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_6731413_1	1163617.SCD_n00549	2.503e-76	260.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
EH2_k127_6731413_0	998674.ATTE01000001_gene4260	2.118e-169	539.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,45ZW7@72273|Thiotrichales	72273|Thiotrichales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_6731631_1	326297.Sama_3298	7.997e-17	82.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8ZG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
EH2_k127_6731631_0	640081.Dsui_1902	1.293e-256	799.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,2KUP1@206389|Rhodocyclales	206389|Rhodocyclales	O	Alkyl hydroperoxide reductase	-	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
EH2_k127_67325_1	1224136.AMFN01000021_gene2337	1.521e-59	209.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,282HE@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_4420,iYL1228.KPN_04135	Hexapep,Hexapep_2,NTP_transf_3
EH2_k127_67325_0	1049564.TevJSym_ax00090	5.868e-232	733.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1J4ET@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
EH2_k127_6739883_3	1150469.RSPPHO_03217	5.993e-11	64.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2TQSU@28211|Alphaproteobacteria,2JR1P@204441|Rhodospirillales	28211|Alphaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
EH2_k127_6739883_2	1198232.CYCME_1673	2.604e-19	92.0	2A25A@1|root,30QFP@2|Bacteria,1QBSW@1224|Proteobacteria,1T7D2@1236|Gammaproteobacteria,463CK@72273|Thiotrichales	72273|Thiotrichales	S	FeoC like transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FeoC
EH2_k127_6739883_0	425104.Ssed_3891	7.208e-23	107.0	COG3295@1|root,COG3295@2|Bacteria,1N1RD@1224|Proteobacteria,1S8VS@1236|Gammaproteobacteria,2QAZQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM PepSY-associated TM helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
EH2_k127_6739883_1	1212548.B381_05176	2.849e-20	96.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1YZQR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
EH2_k127_6770309_0	187272.Mlg_0848	2.961e-65	227.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
EH2_k127_6770309_3	1323663.AROI01000063_gene3850	2.823e-26	110.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
EH2_k127_6770309_2	748247.AZKH_0398	5.415e-30	128.0	COG5581@1|root,COG5581@2|Bacteria,1RJ1B@1224|Proteobacteria,2VTGM@28216|Betaproteobacteria,2KWP1@206389|Rhodocyclales	206389|Rhodocyclales	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
EH2_k127_6770309_1	519989.ECTPHS_04069	1.644e-64	224.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
EH2_k127_6781163_2	1121396.KB893079_gene873	2.271e-46	171.0	COG0517@1|root,COG0517@2|Bacteria,1QQRM@1224|Proteobacteria,42TVT@68525|delta/epsilon subdivisions,2WQBQ@28221|Deltaproteobacteria,2MNSD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_6781163_1	1123393.KB891316_gene1686	7.993e-55	195.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
EH2_k127_6781163_0	338969.Rfer_3852	1.456e-226	709.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,4AFB1@80864|Comamonadaceae	28216|Betaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
EH2_k127_6783450_2	1045855.DSC_07540	1.701e-108	354.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1X5RX@135614|Xanthomonadales	135614|Xanthomonadales	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
EH2_k127_6783450_1	582744.Msip34_1820	2.583e-148	475.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2VIN9@28216|Betaproteobacteria,2KKP7@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
EH2_k127_6783450_0	1049564.TevJSym_av00160	8.786e-287	889.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0008 Glutamyl- and glutaminyl-tRNA synthetases	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
EH2_k127_6783450_3	247633.GP2143_07889	5.159e-37	147.0	2C5G2@1|root,2ZXM4@2|Bacteria,1P4E3@1224|Proteobacteria	1224|Proteobacteria	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
EH2_k127_6785354_1	1163617.SCD_n01593	1.621e-95	315.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
EH2_k127_6785354_0	713586.KB900536_gene929	1.67e-135	450.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
EH2_k127_6786413_0	697282.Mettu_1928	5.842e-93	315.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
EH2_k127_6796242_0	745411.B3C1_01035	9.76e-68	236.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1J609@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	uvrY	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH2_k127_6796242_1	519989.ECTPHS_10346	1.535e-62	217.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,1S2B6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
EH2_k127_6802430_3	1163617.SCD_n00456	1.268e-24	106.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VPW8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	norE	-	1.9.3.1	ko:K02164,ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081,R00294	RC00016,RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10,3.D.4.4,3.D.4.6	-	-	COX3
EH2_k127_6802430_0	472759.Nhal_2479	9.616e-217	691.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales	135613|Chromatiales	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
EH2_k127_6802430_1	105559.Nwat_2283	9.034e-172	549.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1WXJN@135613|Chromatiales	135613|Chromatiales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
EH2_k127_6802430_2	1323663.AROI01000014_gene84	6.925e-138	451.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
EH2_k127_6818594_5	1265313.HRUBRA_00798	1.275e-107	361.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J5K7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	macA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
EH2_k127_6818594_7	153948.NAL212_1954	2.45e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,372J4@32003|Nitrosomonadales	28216|Betaproteobacteria	V	pfam abc	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_6818594_2	2340.JV46_04790	2.655e-143	464.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5FS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_6818594_1	2340.JV46_04780	2.897e-148	480.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_6818594_6	391615.ABSJ01000027_gene205	8.915e-87	292.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1J5E0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_6818594_4	519989.ECTPHS_12943	1.075e-115	387.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1WWCF@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
EH2_k127_6818594_3	653733.Selin_2487	1.08e-132	441.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
EH2_k127_6818594_0	765910.MARPU_10245	2.124e-215	701.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria,1X2S5@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_9
EH2_k127_6827383_0	396588.Tgr7_2119	6.766e-189	593.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH2_k127_684077_0	946483.Cenrod_2395	1.466e-128	415.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
EH2_k127_684077_1	1116472.MGMO_59c00010	3.069e-126	410.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XDMM@135618|Methylococcales	135618|Methylococcales	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
EH2_k127_6844599_3	1278307.KB907006_gene208	3.627e-16	86.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,2QHWX@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
EH2_k127_6844599_1	1485544.JQKP01000002_gene1588	3.134e-201	632.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
EH2_k127_6844599_0	1198232.CYCME_0263	1.748e-259	805.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,461TD@72273|Thiotrichales	72273|Thiotrichales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
EH2_k127_6844599_2	1318628.MARLIPOL_03455	1.044e-114	375.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,465ZB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0117,iSBO_1134.SBO_3961	MTHFR
EH2_k127_6844711_5	1452718.JBOY01000059_gene1592	2.307e-33	134.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	maF-like protein	yhdE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH2_k127_6844711_2	396588.Tgr7_2273	3.834e-63	220.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1WY5P@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
EH2_k127_6844711_4	396588.Tgr7_2274	6.641e-39	149.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales	135613|Chromatiales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
EH2_k127_6844711_3	765914.ThisiDRAFT_0805	1.732e-57	207.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
EH2_k127_6844711_1	1201293.AKXQ01000001_gene1993	1.526e-87	299.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA,Response_reg
EH2_k127_6844711_0	1116472.MGMO_88c00270	3.491e-178	563.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XEVP@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
EH2_k127_6845877_1	1132855.KB913035_gene1597	4.727e-47	173.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2VIYN@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Periplasmic copper-binding	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
EH2_k127_6845877_0	1132855.KB913035_gene1599	0.0	1045.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria	28216|Betaproteobacteria	CK	FMN-binding domain protein	nosR	-	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
EH2_k127_6851899_0	1123393.KB891330_gene873	1.295e-128	423.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
EH2_k127_6875717_1	2340.JV46_24270	6.264e-130	419.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1JA5R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	AIR synthase related protein, N-terminal domain	hypE	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
EH2_k127_6875717_0	2340.JV46_24280	1.098e-229	724.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1J9A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
EH2_k127_6880042_0	1485545.JQLW01000009_gene181	1.092e-94	314.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria	1224|Proteobacteria	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
EH2_k127_6880042_1	56107.Cylst_6349	9.412e-54	194.0	COG0454@1|root,COG0456@2|Bacteria,1G5WX@1117|Cyanobacteria,1HQQR@1161|Nostocales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
EH2_k127_6891627_0	261292.Nit79A3_2533	5.745e-250	772.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,371TZ@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_6891627_1	261292.Nit79A3_2532	1.253e-64	222.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,373DV@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
EH2_k127_6891627_2	1097668.BYI23_C009840	5.727e-13	72.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,1KFNQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
EH2_k127_692491_1	1122201.AUAZ01000007_gene3663	1.229e-57	206.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
EH2_k127_692491_3	243159.AFE_2959	5.835e-37	142.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,2ND6B@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
EH2_k127_692491_0	261292.Nit79A3_1975	2.241e-207	661.0	COG0598@1|root,COG0598@2|Bacteria,1R7FC@1224|Proteobacteria,2VKBA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Magnesium transport protein CorA	-	-	-	-	-	-	-	-	-	-	-	-	CorA
EH2_k127_692491_2	870187.Thini_4145	1.374e-49	183.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,461AY@72273|Thiotrichales	72273|Thiotrichales	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
EH2_k127_692491_4	1123401.JHYQ01000039_gene1548	1.289e-21	94.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,460I9@72273|Thiotrichales	72273|Thiotrichales	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
EH2_k127_693710_1	243233.MCA1585	1.51e-222	703.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,1RN0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	CTI
EH2_k127_693710_4	225937.HP15_3397	4.992e-31	130.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1SGG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
EH2_k127_693710_2	396588.Tgr7_0999	6.433e-195	618.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
EH2_k127_693710_0	396588.Tgr7_0998	2.265e-244	762.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
EH2_k127_693710_3	1049564.TevJSym_ap00510	7.447e-40	153.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1J4U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341,ko:K05559	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
EH2_k127_6948600_2	396588.Tgr7_2621	1.068e-14	76.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1WX3A@135613|Chromatiales	135613|Chromatiales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
EH2_k127_6948600_1	768671.ThimaDRAFT_0950	1.784e-41	160.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S9ZC@1236|Gammaproteobacteria,1WY51@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
EH2_k127_6948600_0	765912.Thimo_2506	4.63e-58	207.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_6955471_0	396588.Tgr7_2002	3.263e-101	331.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1WVV4@135613|Chromatiales	135613|Chromatiales	L	AAA ATPase, central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
EH2_k127_6955471_1	1353529.M899_2773	4.014e-16	85.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,42TM7@68525|delta/epsilon subdivisions,2WS2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH2_k127_695819_0	1095769.CAHF01000014_gene3154	1.477e-182	584.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,472QT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
EH2_k127_695819_2	298386.PBPRB1779	6.48e-27	110.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales	135623|Vibrionales	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_695819_1	768671.ThimaDRAFT_3267	3.637e-95	320.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,1S09M@1236|Gammaproteobacteria,1X09N@135613|Chromatiales	135613|Chromatiales	OQ	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_6961954_3	582744.Msip34_1304	1.357e-35	142.0	COG4338@1|root,COG4338@2|Bacteria,1N3G5@1224|Proteobacteria,2VUMZ@28216|Betaproteobacteria,2KMRW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6961954_0	1283300.ATXB01000001_gene1193	6.706e-84	286.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
EH2_k127_6961954_1	768671.ThimaDRAFT_4663	1.733e-51	187.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1WYDM@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
EH2_k127_6961954_2	768671.ThimaDRAFT_4730	2.271e-45	165.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
EH2_k127_7018421_0	1049564.TevJSym_ak00240	1.709e-119	392.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1JBTU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
EH2_k127_7026283_1	1049564.TevJSym_ba00350	1.495e-197	624.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
EH2_k127_7026283_3	1249627.D779_2446	3.47e-38	149.0	COG5456@1|root,COG5456@2|Bacteria,1RFTY@1224|Proteobacteria,1S4W0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
EH2_k127_7026283_0	768671.ThimaDRAFT_2269	3.701e-200	633.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM cytochrome c oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
EH2_k127_7026283_2	1049564.TevJSym_au00660	1.214e-110	366.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
EH2_k127_7036357_3	159087.Daro_3838	1.434e-121	396.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJYI@28216|Betaproteobacteria,2KUNK@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5,Fer4_6
EH2_k127_7036357_2	870187.Thini_1247	1.184e-130	422.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,462FM@72273|Thiotrichales	72273|Thiotrichales	C	MauM NapG family ferredoxin-type protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
EH2_k127_7036357_0	870187.Thini_1248	0.0	1376.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	napA	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_7036357_11	1430440.MGMSRv2_2005	1.412e-13	73.0	COG3062@1|root,COG3062@2|Bacteria,1PUNQ@1224|Proteobacteria,2V2JR@28211|Alphaproteobacteria,2JUT0@204441|Rhodospirillales	204441|Rhodospirillales	P	NapD protein	-	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
EH2_k127_7036357_9	1027273.GZ77_05765	9.913e-47	175.0	COG1145@1|root,COG1145@2|Bacteria,1N09Y@1224|Proteobacteria,1S4EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin-type protein NapF	napF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9
EH2_k127_7036357_5	697282.Mettu_2584	4.89e-73	262.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales	135618|Methylococcales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
EH2_k127_7036357_10	870187.Thini_1229	1.424e-37	147.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,462M6@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CcmH
EH2_k127_7036357_6	686340.Metal_1027	2.373e-67	234.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1XF10@135618|Methylococcales	135618|Methylococcales	CO	TIGRFAM periplasmic protein thiol	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
EH2_k127_7036357_1	697282.Mettu_2580	6.967e-289	900.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XEQK@135618|Methylococcales	135618|Methylococcales	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
EH2_k127_7036357_7	870187.Thini_1232	8.187e-50	181.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,462I8@72273|Thiotrichales	72273|Thiotrichales	O	CcmE	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
EH2_k127_7036357_12	243233.MCA0420	8.057e-09	58.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,1XFW4@135618|Methylococcales	135618|Methylococcales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
EH2_k127_7036357_4	1283300.ATXB01000001_gene2158	7.671e-115	374.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1XDXU@135618|Methylococcales	135618|Methylococcales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
EH2_k127_7036357_8	395493.BegalDRAFT_0735	7.447e-48	174.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,462B7@72273|Thiotrichales	72273|Thiotrichales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	-	-	-	-	-	-	-	-	-	CcmB
EH2_k127_7053606_1	1095769.CAHF01000022_gene195	9.641e-24	111.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria,2VIMA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_7053606_0	1121935.AQXX01000106_gene572	1.765e-91	307.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XJA6@135619|Oceanospirillales	135619|Oceanospirillales	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
EH2_k127_7057086_1	317025.Tcr_2178	5.98e-06	52.0	2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,1SH6M@1236|Gammaproteobacteria,46388@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7057086_0	375286.mma_3690	8.7e-109	363.0	COG0474@1|root,COG0474@2|Bacteria,1QWMC@1224|Proteobacteria,2VP5S@28216|Betaproteobacteria,473IX@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
EH2_k127_7057453_0	28258.KP05_06785	4.123e-88	293.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales	135619|Oceanospirillales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
EH2_k127_7057453_2	338969.Rfer_2525	2.591e-18	91.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria,4AFCN@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7057453_1	1163617.SCD_n00731	2.277e-83	287.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
EH2_k127_71016_0	713586.KB900536_gene165	9.616e-120	396.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1WWDA@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
EH2_k127_71016_1	443152.MDG893_11666	6.388e-17	80.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,464QD@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2444	PALP
EH2_k127_7105390_1	1182590.BN5_00615	2.802e-107	353.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1YDP6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
EH2_k127_7105390_0	713586.KB900536_gene1377	1.497e-128	427.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales	135613|Chromatiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_7105390_2	1122603.ATVI01000006_gene112	4.354e-72	251.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1X488@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_7129654_1	269799.Gmet_0342	1.138e-20	97.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
EH2_k127_7129654_0	1123392.AQWL01000005_gene3076	2.58e-190	598.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nadh flavin oxidoreductase nadh oxidase	nemA	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
EH2_k127_7130451_0	716541.ECL_01588	4.112e-176	557.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,3X1ET@547|Enterobacter	1236|Gammaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
EH2_k127_7130451_5	396588.Tgr7_0529	3.556e-74	254.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1WWEP@135613|Chromatiales	135613|Chromatiales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
EH2_k127_7130451_6	713586.KB900536_gene1581	4.451e-66	231.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
EH2_k127_7130451_1	765914.ThisiDRAFT_0700	9.685e-150	479.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales	135613|Chromatiales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
EH2_k127_7130451_4	644801.Psest_1109	1.242e-97	328.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1Z0SJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_1304	GHMP_kinases_C,GHMP_kinases_N
EH2_k127_7130451_7	583345.Mmol_1828	8.428e-29	124.0	COG3017@1|root,COG3017@2|Bacteria,1N5H9@1224|Proteobacteria,2VUJP@28216|Betaproteobacteria,2KP9G@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Outer membrane lipoprotein LolB	-	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
EH2_k127_7130451_3	713586.KB900536_gene1585	6.971e-103	357.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
EH2_k127_7130451_2	396588.Tgr7_0523	5.818e-141	456.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
EH2_k127_7133987_1	1283300.ATXB01000001_gene729	1.037e-80	274.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XEPR@135618|Methylococcales	135618|Methylococcales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_7133987_3	1049564.TevJSym_ag00170	5.061e-53	190.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J9QP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Aminotransferase class I and II	hisC	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECO111_1330.ECO111_2745,iSDY_1059.SDY_2220,iSSON_1240.SSON_2092	Aminotran_1_2
EH2_k127_7133987_5	153948.NAL212_0196	1.454e-44	166.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VWSZ@28216|Betaproteobacteria,3731R@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
EH2_k127_7133987_6	391615.ABSJ01000051_gene1098	5.717e-29	124.0	COG1652@1|root,COG1652@2|Bacteria,1NKUE@1224|Proteobacteria	1224|Proteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,LysM
EH2_k127_7133987_4	1396858.Q666_14440	1.745e-45	168.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
EH2_k127_7133987_2	765912.Thimo_1636	1.295e-79	270.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales	135613|Chromatiales	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
EH2_k127_7133987_7	391615.ABSJ01000033_gene683	1.187e-21	99.0	COG3308@1|root,COG3308@2|Bacteria,1NDZM@1224|Proteobacteria,1SF5W@1236|Gammaproteobacteria,1JBJ6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
EH2_k127_7133987_9	765911.Thivi_1071	1.381e-14	81.0	COG3945@1|root,COG3945@2|Bacteria,1R1KK@1224|Proteobacteria,1T552@1236|Gammaproteobacteria,1X2UQ@135613|Chromatiales	135613|Chromatiales	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7133987_10	1209072.ALBT01000052_gene560	7.342e-10	67.0	2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1FHPE@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7133987_0	1124780.ANNU01000006_gene2916	1.162e-100	336.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
EH2_k127_7133987_8	1236542.BALM01000006_gene3192	6.433e-21	93.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,2QA6P@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00132,iE2348C_1286.E2348C_0137,iECBD_1354.ECBD_3485,iECB_1328.ECB_00133,iECD_1391.ECD_00133,iPC815.YPO3401	Pantoate_transf
EH2_k127_7146356_1	935863.AWZR01000002_gene947	1.297e-125	408.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1X3KV@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH2_k127_7146356_2	1121013.P873_11365	9.64e-39	145.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X7FM@135614|Xanthomonadales	135614|Xanthomonadales	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
EH2_k127_7146356_0	396588.Tgr7_2963	7.834e-132	431.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales	135613|Chromatiales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH2_k127_7146356_3	1055815.AYYA01000056_gene177	3.96e-20	92.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,3NJHQ@468|Moraxellaceae	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
EH2_k127_7151101_0	1266925.JHVX01000002_gene901	3.002e-153	493.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,371Y7@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7151101_1	391615.ABSJ01000026_gene114	3.765e-73	253.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,1S50X@1236|Gammaproteobacteria,1J761@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
EH2_k127_7156079_2	697282.Mettu_3203	3.594e-134	433.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XEX8@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_7156079_3	1049564.TevJSym_ap00670	7.519e-100	332.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1J4XT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
EH2_k127_7156079_6	1205753.A989_04768	9.252e-68	243.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1X4AQ@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
EH2_k127_7156079_0	765914.ThisiDRAFT_2001	3.199e-317	981.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales	135613|Chromatiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
EH2_k127_7156079_4	1122211.JMLW01000015_gene1523	5.837e-77	263.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XHHV@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
EH2_k127_7156079_7	472759.Nhal_3154	2.737e-24	105.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1WZBQ@135613|Chromatiales	135613|Chromatiales	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
EH2_k127_7156079_5	396588.Tgr7_0978	1.223e-68	237.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH2_k127_7156079_1	765914.ThisiDRAFT_1998	1.048e-195	617.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
EH2_k127_7157394_4	1163617.SCD_n01356	2.229e-23	103.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
EH2_k127_7157394_0	1163617.SCD_n01357	8.158e-79	273.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
EH2_k127_7157394_3	870187.Thini_4032	1.438e-36	141.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7157394_2	1049564.TevJSym_at00070	2.855e-42	164.0	292F7@1|root,2ZPZF@2|Bacteria,1RGFI@1224|Proteobacteria,1S48P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7157394_1	1123401.JHYQ01000025_gene3310	7.142e-64	226.0	COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,1S0MD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7157394_5	1298867.AUES01000038_gene820	4.086e-08	57.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2UNZ9@28211|Alphaproteobacteria,3K2C1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	PT	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp,cNMP_binding
EH2_k127_719134_0	1535422.ND16A_2615	3.007e-143	467.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,2Q7JF@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Ethylbenzene dehydrogenase	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,EB_dh
EH2_k127_719134_1	1049564.TevJSym_bo00180	1.146e-33	132.0	COG3794@1|root,COG3794@2|Bacteria,1N889@1224|Proteobacteria,1SEU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
EH2_k127_719134_3	159087.Daro_3271	3.715e-29	119.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2VTXS@28216|Betaproteobacteria,2KX2E@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
EH2_k127_719134_2	521719.ATXQ01000007_gene1135	2.401e-32	127.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,1RYUT@1236|Gammaproteobacteria,1YKQ8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Cytochrome D1 heme domain	nirF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
EH2_k127_7206426_0	1216007.AOPM01000071_gene1575	2.113e-96	326.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,2PZUM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440	Ala_racemase_C,Ala_racemase_N
EH2_k127_7206426_1	396588.Tgr7_0927	4.136e-55	194.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
EH2_k127_7213731_0	1454004.AW11_00594	0.0	1208.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KQ71@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH2_k127_7213731_1	204773.HEAR0891	4.323e-87	297.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,4746R@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH2_k127_72292_0	1123514.KB905899_gene1276	1.363e-149	480.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
EH2_k127_72292_1	1123514.KB905899_gene1275	6.993e-138	444.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,463X7@72273|Thiotrichales	72273|Thiotrichales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	6PGD,NAD_binding_2
EH2_k127_7235853_1	1123400.KB904780_gene1918	2.185e-182	572.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH2_k127_7235853_0	2340.JV46_15520	2.519e-237	737.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH2_k127_7235853_2	1163617.SCD_n00462	3.884e-59	212.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
EH2_k127_7259969_3	1120968.AUBX01000009_gene624	3.775e-69	239.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
EH2_k127_7259969_4	631362.Thi970DRAFT_00019	4.64e-35	137.0	2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,1S9KI@1236|Gammaproteobacteria,1X104@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7259969_1	1121935.AQXX01000138_gene3170	7.317e-72	251.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XJNV@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
EH2_k127_7259969_2	1123393.KB891317_gene2332	6.067e-71	246.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria,1KRXZ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH2_k127_7259969_0	519989.ECTPHS_03984	1.504e-77	265.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1WY1K@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM 3'(2'),5'-bisphosphate nucleotidase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
EH2_k127_7275471_5	1288826.MSNKSG1_09693	7.572e-21	99.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria,468YF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
EH2_k127_7275471_2	479434.Sthe_2697	1.917e-79	274.0	COG1656@1|root,COG1977@1|root,COG1656@2|Bacteria,COG1977@2|Bacteria,2G6GZ@200795|Chloroflexi,27Y8I@189775|Thermomicrobia	189775|Thermomicrobia	H	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
EH2_k127_7275471_1	1123401.JHYQ01000008_gene427	1.161e-85	286.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,1RR6R@1236|Gammaproteobacteria,4618B@72273|Thiotrichales	72273|Thiotrichales	P	Putative manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
EH2_k127_7275471_3	748247.AZKH_4491	9.959e-71	250.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,2KXM5@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_7275471_0	1071679.BG57_10360	3.454e-118	406.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
EH2_k127_7275471_7	207954.MED92_12596	2.025e-17	83.0	2EI8B@1|root,332D1@2|Bacteria,1N9M6@1224|Proteobacteria,1SDIK@1236|Gammaproteobacteria,1XRG5@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2835
EH2_k127_7275471_4	519989.ECTPHS_10004	1.42e-53	193.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1WXZ5@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
EH2_k127_7275471_6	153948.NAL212_2721	2.533e-18	86.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VU8X@28216|Betaproteobacteria,373CU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF423)	ygdD	-	-	-	-	-	-	-	-	-	-	-	DUF423
EH2_k127_7275916_2	472759.Nhal_3802	6.357e-73	250.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1WXCY@135613|Chromatiales	135613|Chromatiales	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_7275916_0	748247.AZKH_3583	1.617e-148	477.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,2KVGB@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
EH2_k127_7275916_3	391615.ABSJ01000038_gene406	3.832e-27	119.0	COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,1J6Y2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7275916_1	472759.Nhal_3799	4.57e-112	366.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH2_k127_7275916_4	572477.Alvin_3034	7.119e-19	88.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1WWYM@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
EH2_k127_7277592_2	395493.BegalDRAFT_2465	7.681e-69	248.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
EH2_k127_7277592_4	1046625.AFQY01000003_gene2455	7.962e-12	67.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7277592_3	1260251.SPISAL_02865	1.432e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1WYVU@135613|Chromatiales	135613|Chromatiales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_7277592_0	396588.Tgr7_0941	0.0	1209.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
EH2_k127_7277592_1	765914.ThisiDRAFT_0764	5.648e-167	528.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
EH2_k127_727872_3	765910.MARPU_00100	4.889e-138	443.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1WWT0@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
EH2_k127_727872_0	472759.Nhal_3892	5.206e-273	862.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
EH2_k127_727872_1	396588.Tgr7_3023	9.712e-148	475.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
EH2_k127_727872_5	314278.NB231_06141	7.148e-46	173.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
EH2_k127_727872_4	1049564.TevJSym_bb00160	4.71e-57	206.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1J6DF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
EH2_k127_727872_6	1415780.JPOG01000001_gene3035	3.439e-33	135.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales	135614|Xanthomonadales	NU	pilus assembly protein pilp	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
EH2_k127_727872_2	391615.ABSJ01000042_gene2279	7.352e-144	473.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1J8IZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
EH2_k127_7283994_1	85643.Tmz1t_1891	1.698e-36	143.0	COG5592@1|root,COG5592@2|Bacteria,1QVT0@1224|Proteobacteria,2WGTN@28216|Betaproteobacteria,2KWTB@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
EH2_k127_7283994_3	519989.ECTPHS_02294	2.127e-12	71.0	COG4309@1|root,COG4309@2|Bacteria,1NHRT@1224|Proteobacteria,1SFUF@1236|Gammaproteobacteria,1WZAD@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
EH2_k127_7283994_0	1123368.AUIS01000008_gene2155	9.382e-65	238.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,1T4ST@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7283994_2	640081.Dsui_3318	3.369e-19	86.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,2KUGA@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
EH2_k127_7285083_0	1380391.JIAS01000014_gene2122	7.131e-143	462.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,2JSD0@204441|Rhodospirillales	204441|Rhodospirillales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
EH2_k127_7285083_1	686340.Metal_3155	2.6e-69	243.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
EH2_k127_728728_1	1123368.AUIS01000002_gene1534	5.968e-18	85.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,2NBY2@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH2_k127_728728_0	472759.Nhal_0412	1.053e-216	685.0	COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales	135613|Chromatiales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH2_k127_7311106_11	323850.Shew_0163	7.7e-23	98.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,2QBZM@267890|Shewanellaceae	1236|Gammaproteobacteria	J	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
EH2_k127_7311106_0	1123399.AQVE01000003_gene2038	1.783e-107	351.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,45ZXA@72273|Thiotrichales	72273|Thiotrichales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
EH2_k127_7311106_4	1117319.PSPO_02960	7.458e-70	238.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,2Q23W@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
EH2_k127_7311106_12	227377.CBU_0246	9.45e-13	70.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1JF69@118969|Legionellales	118969|Legionellales	J	structural constituent of ribosome	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
EH2_k127_7311106_10	395493.BegalDRAFT_2615	2.29e-32	127.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,4613R@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
EH2_k127_7311106_5	396588.Tgr7_2314	5.406e-65	223.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1WY84@135613|Chromatiales	135613|Chromatiales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
EH2_k127_7311106_8	1158760.AQXP01000036_gene2415	2.06e-42	158.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales	135613|Chromatiales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
EH2_k127_7311106_1	1122236.KB905141_gene1842	1.298e-90	300.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,2KKCF@206350|Nitrosomonadales	206350|Nitrosomonadales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
EH2_k127_7311106_9	713586.KB900536_gene1157	3.803e-36	139.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1WYNJ@135613|Chromatiales	135613|Chromatiales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
EH2_k127_7311106_6	29486.NJ56_12680	1.681e-51	184.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,41G07@629|Yersinia	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
EH2_k127_7311106_2	396588.Tgr7_2309	1.507e-74	254.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1WXV2@135613|Chromatiales	135613|Chromatiales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
EH2_k127_7311106_7	519989.ECTPHS_13138	5.372e-45	166.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1WZ44@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
EH2_k127_7311106_3	1216007.AOPM01000021_gene3114	4.976e-70	240.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,2PZV7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
EH2_k127_7311106_13	305900.GV64_22990	4.554e-12	67.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1XM99@135619|Oceanospirillales	135619|Oceanospirillales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
EH2_k127_7314346_2	2340.JV46_24180	7.349e-87	293.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1J50E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
EH2_k127_7314346_0	754476.Q7A_631	4.575e-208	652.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
EH2_k127_7314346_3	1049564.TevJSym_ag00070	1.085e-86	293.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1J7JW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
EH2_k127_7314346_4	870187.Thini_1049	7.062e-77	262.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,460HZ@72273|Thiotrichales	72273|Thiotrichales	O	Stringent starvation protein A	-	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N_3
EH2_k127_7314346_5	314278.NB231_05666	6.356e-43	161.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1WYWV@135613|Chromatiales	135613|Chromatiales	S	Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
EH2_k127_7314346_6	153721.MYP_2442	5.494e-05	51.0	2CAXD@1|root,2ZFE9@2|Bacteria,4P87A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7314346_1	519989.ECTPHS_01804	7.386e-159	509.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WXBN@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD linked oxidase domain protein	-	-	1.1.5.12	ko:K03777	ko00620,ko01120,map00620,map01120	-	R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
EH2_k127_731612_1	686340.Metal_3114	1.935e-59	211.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XEY6@135618|Methylococcales	135618|Methylococcales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
EH2_k127_731612_0	1452718.JBOY01000028_gene94	2.366e-131	430.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	DHO_dh
EH2_k127_7334414_1	519989.ECTPHS_05435	1.211e-138	446.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
EH2_k127_7334414_2	768671.ThimaDRAFT_4252	4.251e-36	140.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1WZ4Z@135613|Chromatiales	135613|Chromatiales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
EH2_k127_7334414_0	472759.Nhal_2787	0.0	1349.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1WXTJ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
EH2_k127_7334414_3	1265503.KB905172_gene412	1.764e-25	106.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,2Q6X5@267889|Colwelliaceae	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055	NifU_N
EH2_k127_7345255_2	1300345.LF41_1123	2.476e-38	146.0	COG5395@1|root,COG5395@2|Bacteria,1REYE@1224|Proteobacteria,1S5R8@1236|Gammaproteobacteria,1XBEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
EH2_k127_7345255_0	316067.Geob_0067	3.394e-159	518.0	COG3863@1|root,COG3863@2|Bacteria,1R3R2@1224|Proteobacteria,42S8G@68525|delta/epsilon subdivisions,2WNZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
EH2_k127_7345255_1	296591.Bpro_3822	2.124e-62	219.0	COG4733@1|root,COG4733@2|Bacteria,1QYJ4@1224|Proteobacteria,2WHFV@28216|Betaproteobacteria,4AJWW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
EH2_k127_7352817_3	1163617.SCD_n01883	7.131e-69	235.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
EH2_k127_7352817_1	765911.Thivi_3112	3.601e-107	349.0	COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,1SHQ0@1236|Gammaproteobacteria,1WZZ0@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
EH2_k127_7352817_0	1469245.JFBG01000019_gene1134	1.239e-159	506.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
EH2_k127_7352817_5	1208321.D104_17875	6.175e-30	123.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,1S6W1@1236|Gammaproteobacteria,1XMA7@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
EH2_k127_7352817_4	870187.Thini_2661	3.887e-54	196.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,1S1KD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
EH2_k127_7352817_2	1049564.TevJSym_ag00870	5.823e-101	338.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,1RQT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH2_k127_7376218_0	1123279.ATUS01000001_gene2455	7.812e-79	270.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RZ5E@1236|Gammaproteobacteria,1J8I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
EH2_k127_7376218_1	1117647.M5M_12030	1.42e-55	206.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1JAAK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
EH2_k127_7376218_2	1049564.TevJSym_au00060	6.548e-38	147.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1JAUR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
EH2_k127_7386064_0	314345.SPV1_00095	9.255e-99	334.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_7413754_0	1163617.SCD_n02548	3.061e-87	297.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
EH2_k127_7413754_1	292415.Tbd_0909	2.78e-19	89.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,2VIRV@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
EH2_k127_7421677_0	697282.Mettu_1405	0.0	1130.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales	135618|Methylococcales	H	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
EH2_k127_74430_0	713586.KB900536_gene1356	3.622e-232	730.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
EH2_k127_7449350_0	686340.Metal_2118	1.825e-300	929.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XE1A@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
EH2_k127_7449350_2	697282.Mettu_3679	1.286e-80	269.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XE1A@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
EH2_k127_7449350_1	519989.ECTPHS_00230	1.682e-98	326.0	COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0209 Ribonucleotide reductase, alpha subunit	nrdJb	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_746225_1	261292.Nit79A3_3483	3.823e-131	426.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2VH4R@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
EH2_k127_746225_0	870187.Thini_2814	1.671e-235	734.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,4605R@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
EH2_k127_746337_2	349521.HCH_04142	5.854e-08	55.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1NMCM@1224|Proteobacteria,1SPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
EH2_k127_746337_0	396588.Tgr7_3073	2.188e-165	533.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales	135613|Chromatiales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
EH2_k127_746337_1	2340.JV46_13280	3.421e-42	158.0	2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7470543_2	1266914.ATUK01000012_gene75	4.522e-145	461.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
EH2_k127_7470543_3	396588.Tgr7_0990	6.251e-72	245.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
EH2_k127_7470543_1	396588.Tgr7_0991	1.161e-241	750.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
EH2_k127_7470543_0	396588.Tgr7_0992	1.182e-259	820.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
EH2_k127_7489369_6	224911.27350827	2.94e-06	51.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7489369_2	1123400.KB904757_gene2171	6.355e-73	249.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
EH2_k127_7489369_3	1123401.JHYQ01000020_gene978	1.162e-57	204.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
EH2_k127_7489369_5	1121013.P873_06675	1.375e-36	141.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1X6XJ@135614|Xanthomonadales	135614|Xanthomonadales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
EH2_k127_7489369_4	519989.ECTPHS_04044	3.306e-39	147.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
EH2_k127_7489369_0	1137799.GZ78_24235	4.721e-146	469.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1XI2X@135619|Oceanospirillales	135619|Oceanospirillales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obgE	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
EH2_k127_7489369_1	519989.ECTPHS_04054	3.073e-94	313.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
EH2_k127_750117_0	313612.L8106_04376	4.385e-36	151.0	COG3852@1|root,COG5001@1|root,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales	1117|Cyanobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_750117_1	686340.Metal_3114	8.795e-27	112.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XEY6@135618|Methylococcales	135618|Methylococcales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
EH2_k127_7523815_1	396588.Tgr7_2764	4.816e-195	616.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
EH2_k127_7523815_5	713586.KB900536_gene2595	3.958e-37	146.0	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1WYR7@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0149 family	-	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
EH2_k127_7523815_7	713586.KB900536_gene2594	1.543e-05	51.0	2DQA2@1|root,335JK@2|Bacteria,1NB7S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7523815_6	765911.Thivi_3388	1.377e-21	98.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZ69@135613|Chromatiales	135613|Chromatiales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
EH2_k127_7523815_4	207954.MED92_04674	5.316e-51	187.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XJPQ@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
EH2_k127_7523815_3	523791.Kkor_2472	2.997e-69	237.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XK83@135619|Oceanospirillales	135619|Oceanospirillales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
EH2_k127_7523815_0	765914.ThisiDRAFT_0180	2.784e-231	727.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
EH2_k127_7523815_2	768671.ThimaDRAFT_1418	1.886e-95	317.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1WVVE@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
EH2_k127_7539572_1	396588.Tgr7_1461	8.02e-138	443.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1WWPU@135613|Chromatiales	135613|Chromatiales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH2_k127_7539572_3	519989.ECTPHS_03567	2.336e-64	228.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales	135613|Chromatiales	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
EH2_k127_7539572_0	472759.Nhal_2019	3.462e-226	717.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales	135613|Chromatiales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
EH2_k127_7539572_4	396588.Tgr7_1408	2.848e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,1N3T7@1224|Proteobacteria,1SFI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
EH2_k127_7539572_2	1232410.KI421426_gene1440	1.843e-81	279.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,43UHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bifunctional transglycosylase second domain	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
EH2_k127_7547820_3	870187.Thini_2085	4.057e-68	237.0	COG0431@1|root,COG0431@2|Bacteria,1RGV1@1224|Proteobacteria,1S2U5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
EH2_k127_7547820_4	765913.ThidrDRAFT_2173	4.943e-68	235.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM DJ-1 family protein	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
EH2_k127_7547820_0	857087.Metme_0275	3.183e-161	518.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XEI9@135618|Methylococcales	135618|Methylococcales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
EH2_k127_7547820_2	713586.KB900536_gene2081	7.377e-76	269.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1WX4I@135613|Chromatiales	135613|Chromatiales	D	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH2_k127_7547820_7	765914.ThisiDRAFT_1428	4.653e-47	171.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1WYHD@135613|Chromatiales	135613|Chromatiales	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
EH2_k127_7547820_8	870187.Thini_2012	1.782e-36	142.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4614X@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Rhodanese-like	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_7547820_6	1049564.TevJSym_ap00740	3.853e-53	190.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1J6GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
EH2_k127_7547820_5	323261.Noc_0034	2.319e-53	192.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
EH2_k127_7547820_1	1049564.TevJSym_at00220	1.737e-106	355.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1J4W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iJN746.PP_4169,iSFV_1184.SFV_3923	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
EH2_k127_7547820_9	396588.Tgr7_1360	3.067e-33	138.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria,1WX67@135613|Chromatiales	135613|Chromatiales	K	cyclic nucleotide-binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_7547820_10	301.JNHE01000028_gene816	2.041e-27	113.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1YFZM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
EH2_k127_7562479_1	1298593.TOL_1495	1.2e-77	267.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XHYG@135619|Oceanospirillales	135619|Oceanospirillales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH2_k127_7562479_0	669262.COK_1079	1.457e-97	323.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1Y7B6@135625|Pasteurellales	135625|Pasteurellales	C	dehydrogenase E1 component	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
EH2_k127_7572847_0	314345.SPV1_08456	0.0	1104.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria	1224|Proteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
EH2_k127_7572847_1	396588.Tgr7_2035	1.01e-142	460.0	COG3395@1|root,COG3395@2|Bacteria,1QKU1@1224|Proteobacteria,1TIZB@1236|Gammaproteobacteria,1WXF7@135613|Chromatiales	135613|Chromatiales	S	Type III effector Hrp-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
EH2_k127_7577824_0	472759.Nhal_0500	0.0	1068.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH2_k127_758093_3	1123401.JHYQ01000018_gene2361	9.624e-25	109.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,1S614@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_758093_1	1454004.AW11_03460	2.084e-90	302.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,1KQNA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
EH2_k127_758093_4	227377.CBU_1136	2.177e-12	78.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1JCSU@118969|Legionellales	118969|Legionellales	S	Sel1-like repeats.	-	-	-	ko:K15474	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	Sel1
EH2_k127_758093_2	396588.Tgr7_1421	1.511e-39	162.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1WZ75@135613|Chromatiales	135613|Chromatiales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
EH2_k127_758093_0	1236541.BALL01000025_gene2959	1.862e-152	486.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,2Q9TZ@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
EH2_k127_758093_6	870187.Thini_0358	6.931e-11	63.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,45ZUM@72273|Thiotrichales	72273|Thiotrichales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
EH2_k127_7618003_3	1279017.AQYJ01000027_gene1897	7.088e-05	48.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641	DFP,Flavoprotein
EH2_k127_7618003_0	1397527.Q670_02580	2.541e-150	486.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XIHN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
EH2_k127_7618003_1	357804.Ping_0058	1.191e-75	256.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,2QI1C@267894|Psychromonadaceae	1236|Gammaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
EH2_k127_7618003_2	243365.CV_2172	1.383e-68	238.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,2KQDD@206351|Neisseriales	206351|Neisseriales	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	algC	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_7619094_1	1027273.GZ77_10335	1.11e-58	208.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
EH2_k127_7619094_0	2340.JV46_16550	7.148e-174	548.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1J53B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Aminotransferase	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
EH2_k127_7626696_4	1122947.FR7_0872	3.934e-77	275.0	COG2984@1|root,COG4191@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,1UCKT@1239|Firmicutes,4H2Z5@909932|Negativicutes	909932|Negativicutes	T	PFAM ATP-binding region ATPase domain protein, ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c
EH2_k127_7626696_1	1122915.AUGY01000014_gene2726	3.013e-149	489.0	COG3437@1|root,COG3437@2|Bacteria,1UYCB@1239|Firmicutes,4HE6S@91061|Bacilli,2769T@186822|Paenibacillaceae	91061|Bacilli	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD
EH2_k127_7626696_2	261292.Nit79A3_1737	2.234e-80	269.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH2_k127_7626696_5	1163617.SCD_n02014	9.574e-31	124.0	COG0607@1|root,COG0607@2|Bacteria,1NBYS@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_7626696_3	279714.FuraDRAFT_0689	9.016e-78	266.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Superoxide dismutase	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Sod_Fe_C
EH2_k127_7626696_0	1123392.AQWL01000006_gene608	1.806e-229	717.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1KRYZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
EH2_k127_7637457_2	1049564.TevJSym_bp00040	6.708e-85	287.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1J5QX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
EH2_k127_7637457_3	396588.Tgr7_2415	3.501e-71	244.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales	135613|Chromatiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
EH2_k127_7637457_4	395493.BegalDRAFT_2157	2.184e-61	214.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,460VS@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
EH2_k127_7637457_0	1122951.ATUE01000005_gene2250	6.189e-156	498.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,3NJA9@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_7637457_7	713586.KB900536_gene1199	4.249e-25	114.0	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7637457_6	395493.BegalDRAFT_1306	7.408e-41	156.0	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales	72273|Thiotrichales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
EH2_k127_7637457_5	1255043.TVNIR_3445	2.65e-57	201.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales	135613|Chromatiales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
EH2_k127_7637457_1	754477.Q7C_1162	4.474e-90	301.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH2_k127_7646271_0	396588.Tgr7_1467	7.61e-195	612.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_7646271_1	396588.Tgr7_1481	1.245e-120	390.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
EH2_k127_7646271_2	396588.Tgr7_1482	3.634e-16	82.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales	135613|Chromatiales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
EH2_k127_7653731_3	314231.FP2506_01195	1.296e-23	112.0	COG3550@1|root,COG3550@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
EH2_k127_7653731_2	1123517.JOMR01000001_gene1148	1.564e-56	202.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,460U2@72273|Thiotrichales	72273|Thiotrichales	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
EH2_k127_7653731_1	1123401.JHYQ01000024_gene1298	6.879e-135	439.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,461RJ@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
EH2_k127_7653731_0	1323663.AROI01000014_gene84	8.908e-160	513.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
EH2_k127_7659270_2	580332.Slit_1450	2.144e-124	400.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria,44W77@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
EH2_k127_7659270_0	686340.Metal_3575	3.16e-322	1010.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XG74@135618|Methylococcales	135618|Methylococcales	P	Cation transporter/ATPase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
EH2_k127_7659270_1	1163617.SCD_n00015	8.074e-131	424.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
EH2_k127_7670512_0	1288494.EBAPG3_6510	5.098e-132	426.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,371QK@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	rbcR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_7670512_1	261292.Nit79A3_3235	4.771e-109	353.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,371TS@32003|Nitrosomonadales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
EH2_k127_7679760_0	396588.Tgr7_3057	1.442e-196	624.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales	135613|Chromatiales	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
EH2_k127_7679760_1	859657.RPSI07_2891	8.79e-40	151.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1K7QJ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
EH2_k127_7679760_2	1165096.ARWF01000001_gene1974	1.974e-35	140.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,2KKKB@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
EH2_k127_7684793_0	1260251.SPISAL_01180	3.677e-172	561.0	COG0475@1|root,COG1226@1|root,COG3273@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,COG3273@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1WX9W@135613|Chromatiales	135613|Chromatiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
EH2_k127_7684793_2	396588.Tgr7_0937	2.785e-124	403.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1WWX4@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
EH2_k127_7684793_6	748280.NH8B_1148	2.203e-07	57.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7684793_5	1122164.JHWF01000022_gene1733	6.132e-08	53.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7684793_1	396588.Tgr7_0938	1.056e-126	418.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1WWKF@135613|Chromatiales	135613|Chromatiales	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
EH2_k127_7684793_3	519989.ECTPHS_10936	9.085e-110	357.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1WW24@135613|Chromatiales	135613|Chromatiales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
EH2_k127_7684793_4	396588.Tgr7_0940	1.163e-68	234.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
EH2_k127_7685556_2	2340.JV46_22100	3.941e-11	67.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1J665@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
EH2_k127_7685556_1	1163617.SCD_n02498	2.172e-32	132.0	COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,2W3S0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7685556_0	1163617.SCD_n02497	1.63e-73	255.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,DUF302
EH2_k127_7699432_5	1198232.CYCME_1994	1.861e-11	68.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,460N9@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_2,TPR_8
EH2_k127_7699432_4	713586.KB900536_gene444	2.24e-23	113.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1WYDK@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
EH2_k127_7699432_0	396588.Tgr7_2048	8.948e-181	574.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales	135613|Chromatiales	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
EH2_k127_7699432_2	396588.Tgr7_2047	1.18e-46	176.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1WY25@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
EH2_k127_7699432_1	396588.Tgr7_2046	8.385e-91	311.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1WWQT@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
EH2_k127_7699432_3	1122201.AUAZ01000021_gene3217	5.962e-27	110.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,464AT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
EH2_k127_7702046_4	1117647.M5M_05210	8.959e-46	167.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1J5QF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	2.6.1.104,2.6.1.59	ko:K02805,ko:K18653	-	-	R10698	RC00006,RC00781	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
EH2_k127_7702046_0	1117647.M5M_05215	4.714e-150	484.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1J4YZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
EH2_k127_7702046_1	1117647.M5M_05260	2.974e-103	341.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1J7M0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
EH2_k127_7702046_3	1120999.JONM01000005_gene3863	2.991e-58	205.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,2KQVA@206351|Neisseriales	206351|Neisseriales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
EH2_k127_7702046_2	1123392.AQWL01000004_gene2527	8.353e-96	325.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,1KRZF@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
EH2_k127_7733096_0	1169143.KB911035_gene2454	0.0	1003.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,1K1A2@119060|Burkholderiaceae	28216|Betaproteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
EH2_k127_7733490_0	179408.Osc7112_5577	1.924e-21	108.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
EH2_k127_7733696_4	1163617.SCD_n02694	1.067e-37	141.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
EH2_k127_7733696_2	1163617.SCD_n02693	2.494e-73	253.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_7733696_3	1163617.SCD_n02692	1.513e-47	171.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
EH2_k127_7733696_1	1163617.SCD_n02691	2.904e-83	277.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
EH2_k127_7733696_0	1163617.SCD_n02690	7.508e-92	302.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
EH2_k127_7737410_0	713586.KB900536_gene2721	1.764e-110	365.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
EH2_k127_7737410_1	519989.ECTPHS_09043	1.543e-20	94.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
EH2_k127_7766942_0	472759.Nhal_2348	2.739e-160	513.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1WVYU@135613|Chromatiales	135613|Chromatiales	N	ATPase FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
EH2_k127_7766942_6	765912.Thimo_0272	3.456e-27	118.0	COG1317@1|root,COG1317@2|Bacteria,1RA31@1224|Proteobacteria,1S37U@1236|Gammaproteobacteria,1WY5D@135613|Chromatiales	135613|Chromatiales	N	PFAM Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
EH2_k127_7766942_2	396588.Tgr7_1968	6.192e-129	420.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales	135613|Chromatiales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
EH2_k127_7766942_3	396588.Tgr7_1969	2.12e-128	428.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1WWW8@135613|Chromatiales	135613|Chromatiales	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
EH2_k127_7766942_7	1283300.ATXB01000001_gene957	2.609e-24	105.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1XFGH@135618|Methylococcales	135618|Methylococcales	N	PFAM Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
EH2_k127_7766942_1	1121374.KB891586_gene2839	4.678e-141	460.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_7766942_4	640081.Dsui_1757	8.178e-62	229.0	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,2VKT0@28216|Betaproteobacteria,2KZWU@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
EH2_k127_7766942_5	1056512.D515_04564	5.48e-38	144.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XSUQ@135623|Vibrionales	135623|Vibrionales	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	ygdL	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
EH2_k127_776877_3	1198452.Jab_1c07830	0.0002231	46.0	COG4932@1|root,COG4932@2|Bacteria,1R2PP@1224|Proteobacteria,2WICC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_776877_0	768671.ThimaDRAFT_2533	4.548e-167	531.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales	135613|Chromatiales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
EH2_k127_776877_1	640081.Dsui_1429	2.07e-127	447.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_1
EH2_k127_776877_2	391615.ABSJ01000022_gene341	5.468e-71	244.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4RW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA helicase	uvrD	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH2_k127_7774104_2	1132855.KB913035_gene1595	5.763e-85	289.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2VJDE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
EH2_k127_7774104_1	748247.AZKH_2411	1.365e-98	332.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,2KWZW@206389|Rhodocyclales	206389|Rhodocyclales	V	COG1131 ABC-type multidrug transport system, ATPase component	nosF	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
EH2_k127_7774104_0	1132855.KB913035_gene1597	1.407e-150	478.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2VIYN@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Periplasmic copper-binding	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
EH2_k127_7776717_3	754476.Q7A_2192	3.917e-39	146.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4600U@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
EH2_k127_7776717_1	1163617.SCD_n00886	3.48e-115	385.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
EH2_k127_7776717_6	1198232.CYCME_1512	1.022e-13	78.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
EH2_k127_7776717_4	754476.Q7A_2021	4.013e-33	135.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Colicin v production	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
EH2_k127_7776717_0	1215092.PA6_027_01140	5.443e-233	729.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1YEFI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,Pribosyltran
EH2_k127_7776717_5	666681.M301_0516	5.21e-21	103.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,2KKK5@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3,TPR_16,TPR_17
EH2_k127_7776717_2	1122599.AUGR01000023_gene4168	9.078e-94	321.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,1RREZ@1236|Gammaproteobacteria,1XHCA@135619|Oceanospirillales	135619|Oceanospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH2_k127_7782073_0	1116472.MGMO_49c00030	0.0	1422.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1XDPR@135618|Methylococcales	135618|Methylococcales	G	PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal	-	GO:0003674,GO:0003824,GO:0008150,GO:0009758	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
EH2_k127_7794009_4	1429851.X548_15345	5.381e-09	66.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,1RSFR@1236|Gammaproteobacteria,1XCTZ@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
EH2_k127_7794009_0	1163617.SCD_n00030	2.364e-241	758.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE1	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
EH2_k127_7794009_3	864051.BurJ1DRAFT_0044	2.922e-23	100.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,1KMJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
EH2_k127_7794009_1	396588.Tgr7_1360	6.844e-60	215.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria,1WX67@135613|Chromatiales	135613|Chromatiales	K	cyclic nucleotide-binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_7794009_2	1123257.AUFV01000016_gene3520	2.338e-55	196.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1X6G6@135614|Xanthomonadales	135614|Xanthomonadales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
EH2_k127_7811818_0	1232683.ADIMK_3005	3.939e-139	451.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4664T@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	ygaD	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
EH2_k127_7811818_3	713586.KB900536_gene1974	6.116e-103	353.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1WVYB@135613|Chromatiales	135613|Chromatiales	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
EH2_k127_7811818_4	472759.Nhal_1457	1.047e-50	192.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1WZGU@135613|Chromatiales	135613|Chromatiales	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
EH2_k127_7811818_2	1288494.EBAPG3_19700	9.105e-106	355.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
EH2_k127_7811818_1	1123393.KB891317_gene2217	4.985e-106	349.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,1KSEB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH2_k127_7811818_5	2340.JV46_11580	3.731e-06	55.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1J6EU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
EH2_k127_78295_3	713586.KB900536_gene1665	1.481e-09	60.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH2_k127_78295_2	1121895.Q765_02760	1.808e-39	150.0	COG0614@1|root,COG0614@2|Bacteria,4NRTJ@976|Bacteroidetes,1IJ3W@117743|Flavobacteriia,2P0IS@237|Flavobacterium	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
EH2_k127_78295_1	349521.HCH_06126	1.755e-98	325.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XH6R@135619|Oceanospirillales	135619|Oceanospirillales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
EH2_k127_78295_0	870187.Thini_3914	1.325e-186	590.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,460C8@72273|Thiotrichales	72273|Thiotrichales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_7840581_0	1121918.ARWE01000001_gene2479	2.486e-194	625.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,Response_reg
EH2_k127_7840581_1	1121935.AQXX01000136_gene4091	3.02e-128	435.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,1RYHZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HDOD
EH2_k127_7854172_0	1163617.SCD_n00655	1.178e-151	484.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
EH2_k127_7854172_1	1049564.TevJSym_ap00660	1.01e-121	398.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1J55X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3206	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_7858256_1	1249634.D781_4323	2.526e-08	63.0	COG3266@1|root,COG3266@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,400UG@613|Serratia	1236|Gammaproteobacteria	D	Cell division protein DamX	damX	GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
EH2_k127_7858256_0	1123514.KB905900_gene2155	1.821e-48	174.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales	72273|Thiotrichales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
EH2_k127_7910701_1	391615.ABSJ01000042_gene2252	1.294e-86	287.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1J4KJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein, pilus retraction ATPase PilT	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_7910701_2	1117647.M5M_11295	3.122e-80	273.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1J61Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
EH2_k127_7910701_0	477228.YO5_19147	3.203e-89	305.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1Z2AR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
EH2_k127_7910701_3	765913.ThidrDRAFT_2114	3.602e-44	169.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales	135613|Chromatiales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
EH2_k127_7910701_4	1136138.JH604624_gene3961	1.003e-28	118.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0235 family	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
EH2_k127_79171_1	396588.Tgr7_0252	1.437e-35	145.0	COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,OMP_b-brl
EH2_k127_79171_0	1232683.ADIMK_2712	3.199e-72	256.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,464VU@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
EH2_k127_7929061_3	2340.JV46_16980	2.635e-08	55.0	COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin
EH2_k127_7929061_2	292415.Tbd_2606	2.567e-16	80.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_7929061_0	391615.ABSJ01000037_gene831	9.695e-72	249.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,1SPF2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7929061_1	472759.Nhal_3472	1.936e-23	108.0	2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,1SBQY@1236|Gammaproteobacteria,1WZRS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_795345_11	32042.PstZobell_06103	4.775e-42	163.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,1Z0D0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
EH2_k127_795345_9	523791.Kkor_0477	4.995e-61	214.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XJWN@135619|Oceanospirillales	135619|Oceanospirillales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
EH2_k127_795345_5	713586.KB900536_gene510	1.74e-95	322.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
EH2_k127_795345_13	1244869.H261_17908	1.329e-17	87.0	COG0745@1|root,COG2200@1|root,COG0745@2|Bacteria,COG2200@2|Bacteria,1NWAF@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	3.1.4.52	ko:K13246	ko05111,map05111	-	R08991	RC00296	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,GerE,HD,HTH_18,HWE_HK,HisKA_2,PAS,PAS_3,PAS_9,Response_reg,SpoIIE,Trans_reg_C
EH2_k127_795345_3	1265503.KB905181_gene3774	9.55e-103	362.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_795345_12	1243664.CAVL020000047_gene2253	5.46e-22	102.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus	91061|Bacilli	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
EH2_k127_795345_15	86416.Clopa_0647	2.943e-06	53.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36DJA@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
EH2_k127_795345_10	1177181.T9A_00592	6.989e-44	164.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XK4R@135619|Oceanospirillales	135619|Oceanospirillales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
EH2_k127_795345_7	1123399.AQVE01000007_gene1089	4.241e-65	226.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,460J0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
EH2_k127_795345_1	396588.Tgr7_1561	7.536e-158	506.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
EH2_k127_795345_4	870187.Thini_0913	1.274e-97	323.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
EH2_k127_795345_8	391615.ABSJ01000037_gene919	1.414e-64	226.0	COG5405@1|root,COG5405@2|Bacteria,1RAFD@1224|Proteobacteria	1224|Proteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
EH2_k127_795345_2	519989.ECTPHS_05866	1.998e-139	454.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
EH2_k127_795345_6	396588.Tgr7_1558	3.673e-68	233.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1WX91@135613|Chromatiales	135613|Chromatiales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
EH2_k127_795345_0	2340.JV46_06560	3.28e-226	705.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1J4EX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
EH2_k127_795345_14	1122134.KB893650_gene670	1.36e-12	70.0	28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,1RZT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7968717_1	1000565.METUNv1_02451	2.509e-69	238.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
EH2_k127_7968717_0	396588.Tgr7_0952	1.804e-87	298.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1SZ5G@1236|Gammaproteobacteria,1WWSY@135613|Chromatiales	135613|Chromatiales	T	PFAM protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,SpoIIE
EH2_k127_8016760_0	498211.CJA_2635	4.163e-234	727.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1FG0R@10|Cellvibrio	1236|Gammaproteobacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
EH2_k127_8016760_2	1236541.BALL01000019_gene2544	7.02e-38	155.0	COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,2Q9B1@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	motY	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
EH2_k127_8016760_1	585.DR95_2665	6.925e-57	203.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,3Z2D5@583|Proteus	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH2_k127_8016760_3	498211.CJA_1389	5.269e-32	126.0	COG1702@1|root,COG1702@2|Bacteria,1PNF2@1224|Proteobacteria,1RNZ7@1236|Gammaproteobacteria,1FG1H@10|Cellvibrio	1236|Gammaproteobacteria	T	PhoH-like protein	phoH	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
EH2_k127_8042718_1	713586.KB900536_gene2278	3.69e-43	162.0	2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria,1WY9W@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
EH2_k127_8042718_0	318161.Sden_3396	2.37e-102	348.0	COG3322@1|root,COG5001@1|root,COG3322@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8UJ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_9,Response_reg
EH2_k127_8049981_7	1415779.JOMH01000001_gene201	1.916e-45	168.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1X38K@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
EH2_k127_8049981_4	314287.GB2207_06288	3.757e-119	391.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1J4GJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
EH2_k127_8049981_5	323261.Noc_1723	1.756e-112	377.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
EH2_k127_8049981_3	519989.ECTPHS_02531	5.367e-145	487.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
EH2_k127_8049981_2	396588.Tgr7_2465	5.807e-148	473.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales	135613|Chromatiales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH2_k127_8049981_0	631362.Thi970DRAFT_01081	3.596e-164	524.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH2_k127_8049981_6	2340.JV46_08600	8.194e-60	214.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
EH2_k127_8049981_1	396588.Tgr7_2461	3.987e-153	490.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH2_k127_80944_1	243233.MCA3077	3.128e-72	251.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XDJA@135618|Methylococcales	135618|Methylococcales	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
EH2_k127_80944_0	765914.ThisiDRAFT_1372	5.49e-109	368.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1WX3X@135613|Chromatiales	135613|Chromatiales	N	PFAM ABC-type uncharacterised transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
EH2_k127_80944_2	243233.MCA3075	5.043e-27	121.0	2E2KI@1|root,32XPU@2|Bacteria,1RH64@1224|Proteobacteria,1RYC7@1236|Gammaproteobacteria,1XGH6@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
EH2_k127_80944_3	1137799.GZ78_21805	1.082e-11	68.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XH8W@135619|Oceanospirillales	135619|Oceanospirillales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
EH2_k127_8110811_2	1283300.ATXB01000001_gene729	7.037e-07	50.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XEPR@135618|Methylococcales	135618|Methylococcales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_8110811_0	391615.ABSJ01000055_gene1370	1.626e-96	328.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1J4WE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degS	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
EH2_k127_8110811_1	1122599.AUGR01000005_gene1733	7.994e-84	287.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XIMF@135619|Oceanospirillales	135619|Oceanospirillales	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
EH2_k127_8134592_1	192952.MM_0391	1.154e-53	194.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
EH2_k127_8134592_0	1212548.B381_12378	1.761e-129	422.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1Z2G7@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
EH2_k127_8153650_0	83406.HDN1F_00940	1.63e-05	56.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1J501@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Adenylate cyclase	cyaA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365	Adenyl_cycl_N,Adenylate_cycl
EH2_k127_8161536_1	870187.Thini_1186	2.694e-148	471.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
EH2_k127_8161536_3	1123401.JHYQ01000015_gene1407	4.481e-51	182.0	2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,462XP@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_8161536_2	765912.Thimo_0766	5.633e-60	210.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S3XZ@1236|Gammaproteobacteria,1X23Q@135613|Chromatiales	135613|Chromatiales	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
EH2_k127_8161536_0	1123401.JHYQ01000015_gene1409	5.277e-312	956.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
EH2_k127_8204441_0	396588.Tgr7_1464	1.101e-122	404.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
EH2_k127_8204441_2	2340.JV46_18230	4.049e-34	134.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1J6QM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	sdhC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
EH2_k127_8204441_3	713586.KB900536_gene2989	1.118e-20	96.0	COG2142@1|root,COG2142@2|Bacteria,1RH1K@1224|Proteobacteria,1S7GT@1236|Gammaproteobacteria,1WYKS@135613|Chromatiales	135613|Chromatiales	C	Succinate dehydrogenase hydrophobic membrane anchor	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
EH2_k127_8204441_1	713586.KB900536_gene372	1.659e-121	394.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_821022_0	1120792.JAFV01000001_gene3122	9.048e-219	686.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2TRUJ@28211|Alphaproteobacteria,36YVT@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	MA20_45030	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_821022_1	1454004.AW11_02632	1.201e-130	426.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
EH2_k127_821022_5	765911.Thivi_1130	1.988e-25	108.0	2EE2B@1|root,337X1@2|Bacteria,1N433@1224|Proteobacteria,1SB80@1236|Gammaproteobacteria,1WZ02@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_821022_2	765914.ThisiDRAFT_1869	4.863e-124	422.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales	135613|Chromatiales	M	PFAM Lytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
EH2_k127_821022_3	1278971.AOGF01000014_gene1589	4.062e-70	252.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
EH2_k127_821022_4	1123392.AQWL01000006_gene651	1.575e-37	144.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KT6E@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
EH2_k127_840362_3	1123401.JHYQ01000001_gene1810	3.764e-45	167.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	chain release factor	yaeJ	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
EH2_k127_840362_5	2340.JV46_24320	9.544e-33	127.0	COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	TIGRFAM hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH2_k127_840362_4	2340.JV46_24310	3.724e-43	162.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
EH2_k127_840362_1	2340.JV46_24300	4.52e-134	431.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
EH2_k127_840362_0	2340.JV46_24290	6.54e-193	606.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1J9VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Hydrogenase formation hypA family	hypD	GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
EH2_k127_840362_2	2340.JV46_24280	7.486e-78	264.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1J9A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
EH2_k127_842921_1	1131553.JIBI01000015_gene642	6.219e-05	47.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,372F1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
EH2_k127_842921_0	1215092.PA6_033_00600	5.165e-28	131.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,1YDHW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_842955_0	1286106.MPL1_04322	8.182e-93	310.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,46009@72273|Thiotrichales	72273|Thiotrichales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
EH2_k127_842955_2	557598.LHK_03207	3.973e-21	95.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,2KRW6@206351|Neisseriales	206351|Neisseriales	L	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
EH2_k127_842955_1	1485544.JQKP01000002_gene1434	5.549e-73	250.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
EH2_k127_852510_0	1123393.KB891316_gene1644	1.319e-140	449.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
EH2_k127_852510_1	1049564.TevJSym_ac01690	1.038e-85	290.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,1JA86@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
EH2_k127_857997_1	87626.PTD2_04958	2.969e-08	55.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_857997_0	1111728.ATYS01000002_gene2014	5.891e-187	591.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
EH2_k127_857997_2	396588.Tgr7_0976	9.516e-08	54.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,1S6E7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
EH2_k127_862363_1	1123487.KB892834_gene2803	4.52e-62	218.0	COG1246@1|root,COG1595@1|root,COG1246@2|Bacteria,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria,2KWKE@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_862363_0	765911.Thivi_1664	6.279e-163	519.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1WX27@135613|Chromatiales	135613|Chromatiales	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
EH2_k127_862363_4	518766.Rmar_0375	1.845e-30	126.0	COG0394@1|root,COG0394@2|Bacteria,4NNN6@976|Bacteroidetes,1FJIJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
EH2_k127_862363_2	749222.Nitsa_0560	1.969e-42	160.0	COG0607@1|root,COG0607@2|Bacteria,1N45X@1224|Proteobacteria,42T79@68525|delta/epsilon subdivisions,2YPIK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_862363_3	1167006.UWK_01460	2.062e-36	141.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MHP2@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,Methyltransf_31
EH2_k127_871848_2	342610.Patl_0055	2.131e-52	194.0	COG0478@1|root,COG0478@2|Bacteria,1QUI1@1224|Proteobacteria,1T1ZR@1236|Gammaproteobacteria,2Q5H0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
EH2_k127_871848_0	187272.Mlg_2637	1.995e-93	321.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales	135613|Chromatiales	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N,Kdo
EH2_k127_871848_1	1488328.JMCL01000114_gene4246	2.827e-55	201.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068	Lip_A_acyltrans
EH2_k127_88189_1	1366050.N234_10425	6.963e-111	361.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,2WHH3@28216|Betaproteobacteria,1KIP3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
EH2_k127_88189_0	765911.Thivi_3671	1.634e-215	682.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXWA@135613|Chromatiales	135613|Chromatiales	U	sulphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_88189_2	582899.Hden_2023	9.914e-80	269.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,3N6FG@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
EH2_k127_927639_2	1123392.AQWL01000005_gene3217	1.106e-140	455.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KRQV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,GATase_3
EH2_k127_927639_1	413404.Rmag_0859	1.821e-148	480.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
EH2_k127_927639_3	1255043.TVNIR_0850	1.327e-109	359.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
EH2_k127_927639_4	1123401.JHYQ01000005_gene281	3.145e-27	117.0	2E6CU@1|root,3310G@2|Bacteria,1NBK1@1224|Proteobacteria,1S5EP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_927639_0	1123401.JHYQ01000005_gene280	1.097e-248	778.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,463NI@72273|Thiotrichales	72273|Thiotrichales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
EH2_k127_940100_2	1127673.GLIP_4180	2.662e-05	48.0	COG3216@1|root,COG3216@2|Bacteria,1N1Q6@1224|Proteobacteria,1S9HF@1236|Gammaproteobacteria,467XY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062
EH2_k127_940100_0	1298593.TOL_1032	2.25e-80	290.0	COG2982@1|root,COG2982@2|Bacteria,1P6EN@1224|Proteobacteria,1S1EC@1236|Gammaproteobacteria,1XKNN@135619|Oceanospirillales	135619|Oceanospirillales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_940100_1	1232410.KI421426_gene1423	1.716e-55	205.0	COG2199@1|root,COG3706@2|Bacteria,1PFC9@1224|Proteobacteria,4345Y@68525|delta/epsilon subdivisions,2X1UV@28221|Deltaproteobacteria,43V8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
EH2_k127_9483_0	1283300.ATXB01000001_gene1951	1.61e-157	505.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XDV1@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
EH2_k127_97533_1	1123399.AQVE01000024_gene2795	1.357e-63	221.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
EH2_k127_97533_0	1123399.AQVE01000024_gene2794	5.028e-97	325.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,462E0@72273|Thiotrichales	72273|Thiotrichales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
EH2_k127_993893_0	1288494.EBAPG3_1460	2.144e-95	317.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,371YI@32003|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
## 2727 queries scanned
## Total time (seconds): 45.117255210876465
## Rate: 60.44 q/s