## Wed Oct 16 11:23:14 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/EH2_bin.6.fa -m mmseqs --itype genome -o EH2_bin.6 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/EH2_bin.6 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
EH2_k127_1017508_1	1163617.SCD_n00064	4.137e-55	203.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_1017508_0	1163617.SCD_n00063	5.643e-148	489.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_1052552_1	1163617.SCD_n00876	8.17e-215	670.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_1052552_8	558884.JRGM01000176_gene1378	5.59e-20	101.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1Y4QA@135624|Aeromonadales	135624|Aeromonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_1052552_2	1123393.KB891316_gene1194	2.155e-150	507.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KRKB@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
EH2_k127_1052552_9	1123368.AUIS01000006_gene613	9.455e-16	85.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,1SIPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
EH2_k127_1052552_6	640081.Dsui_3194	3.378e-103	341.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,2KU8S@206389|Rhodocyclales	206389|Rhodocyclales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
EH2_k127_1052552_7	580332.Slit_2116	2.35e-75	263.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
EH2_k127_1052552_0	1123393.KB891316_gene1190	2.581e-232	721.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1KRBS@119069|Hydrogenophilales	119069|Hydrogenophilales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH2_k127_1052552_5	1163617.SCD_n00884	5.001e-106	366.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
EH2_k127_1052552_3	1123392.AQWL01000001_gene1533	6.831e-135	435.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,1KRX7@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
EH2_k127_1052552_4	1163617.SCD_n00886	9.429e-130	427.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
EH2_k127_1052552_10	1123487.KB892838_gene3863	1.917e-07	56.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,2KWXH@206389|Rhodocyclales	206389|Rhodocyclales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
EH2_k127_1064651_4	1027273.GZ77_05615	3.2e-16	83.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XJWG@135619|Oceanospirillales	135619|Oceanospirillales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
EH2_k127_1064651_3	1123393.KB891316_gene1180	1.48e-72	257.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KSZ7@119069|Hydrogenophilales	119069|Hydrogenophilales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
EH2_k127_1064651_1	1163617.SCD_n00896	1.633e-106	362.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH2_k127_1064651_2	640081.Dsui_3085	1.887e-87	301.0	COG0457@1|root,COG4319@1|root,COG0457@2|Bacteria,COG4319@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,2KUGG@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17
EH2_k127_1064651_0	1163617.SCD_n00898	1.509e-150	479.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
EH2_k127_111848_4	228410.NE2068	3.521e-22	107.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,373D2@32003|Nitrosomonadales	28216|Betaproteobacteria	M	shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
EH2_k127_111848_2	1144319.PMI16_03164	8.412e-64	230.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,47326@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
EH2_k127_111848_0	1163617.SCD_n00097	2.697e-197	617.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
EH2_k127_111848_3	1304883.KI912532_gene696	9.694e-38	143.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KWWQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
EH2_k127_111848_1	1123393.KB891330_gene842	9.385e-157	499.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KSIC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
EH2_k127_1145934_1	292415.Tbd_1717	6.468e-84	283.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,1KRK8@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_1145934_3	1123392.AQWL01000008_gene1204	6.701e-27	119.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,2W4FH@28216|Betaproteobacteria,1KT96@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1145934_0	1485544.JQKP01000014_gene1900	1.738e-109	358.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
EH2_k127_1145934_2	292415.Tbd_0945	1.349e-72	251.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoglycolate phosphatase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH2_k127_1145934_4	882378.RBRH_00061	7.439e-05	46.0	2AH8R@1|root,317IT@2|Bacteria,1PYVZ@1224|Proteobacteria,2WE0H@28216|Betaproteobacteria,1KBCY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1180890_0	391038.Bphy_2639	0.0	1249.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1K1JU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
EH2_k127_1211624_1	1123392.AQWL01000002_gene1980	4.778e-28	117.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1KSIB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
EH2_k127_1211624_0	1123392.AQWL01000002_gene1898	6.01e-80	271.0	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,2WBPG@28216|Betaproteobacteria,1KSB5@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1262686_2	1276756.AUEX01000038_gene319	6.19e-57	205.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2W334@28216|Betaproteobacteria,4AJRG@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	-
EH2_k127_1262686_3	330214.NIDE0065	7.371e-54	191.0	29X4J@1|root,30ITG@2|Bacteria,3J1BS@40117|Nitrospirae	40117|Nitrospirae	S	MerT mercuric transport protein	merT	-	-	ko:K08363	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	MerT
EH2_k127_1262686_6	887898.HMPREF0551_1415	2.749e-28	123.0	COG2608@1|root,COG2608@2|Bacteria,1N95B@1224|Proteobacteria,2VSRA@28216|Betaproteobacteria,1K9UM@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein	merP	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
EH2_k127_1262686_4	330214.NIDE0067	4.15e-40	154.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1262686_0	1163617.SCD_n01489	3.869e-262	815.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
EH2_k127_1262686_5	566466.NOR53_3671	2.883e-35	139.0	COG2119@1|root,COG2119@2|Bacteria,1N85A@1224|Proteobacteria,1SAAX@1236|Gammaproteobacteria,1JB92@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
EH2_k127_1262686_1	1163617.SCD_n01490	2.886e-167	529.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
EH2_k127_12855_3	1163617.SCD_n00942	4.188e-132	422.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
EH2_k127_12855_4	1123393.KB891327_gene380	1.323e-73	257.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,1KS1X@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
EH2_k127_12855_1	292415.Tbd_1147	1.634e-239	744.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,1KS1J@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
EH2_k127_12855_0	1123392.AQWL01000003_gene390	1.661e-271	856.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1KR9S@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3
EH2_k127_12855_2	1123393.KB891327_gene383	8.97e-157	500.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,1KRDN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
EH2_k127_1306225_0	1123392.AQWL01000006_gene564	2.283e-70	243.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KSQG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
EH2_k127_1306225_1	1123392.AQWL01000002_gene1877	1.305e-52	189.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,2VX7W@28216|Betaproteobacteria,1KT27@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1306225_3	1123392.AQWL01000002_gene1876	4.769e-20	92.0	2AG05@1|root,31646@2|Bacteria,1PWTJ@1224|Proteobacteria,2WCCA@28216|Betaproteobacteria,1KTET@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1306225_2	640081.Dsui_0227	2.555e-36	139.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH2_k127_1306645_0	1000565.METUNv1_02426	1.751e-207	649.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
EH2_k127_1306645_2	292415.Tbd_1890	1.365e-107	353.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,1KRDJ@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
EH2_k127_1306645_1	1123392.AQWL01000008_gene1201	3.288e-189	599.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,1KS1T@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
EH2_k127_1309384_1	1348657.M622_06210	2.565e-37	147.0	2CDHM@1|root,344GF@2|Bacteria,1NZYE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1309384_0	1458427.BAWN01000020_gene1218	0.0	1015.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9Z9@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH2_k127_1350804_4	292415.Tbd_0620	3.108e-20	90.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KRZE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
EH2_k127_1350804_0	1123393.KB891328_gene662	6.773e-219	688.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,1KSF7@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
EH2_k127_1350804_3	1163617.SCD_n01609	1.1e-26	111.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
EH2_k127_1350804_2	1120999.JONM01000003_gene2643	3.048e-57	217.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,2KPC0@206351|Neisseriales	206351|Neisseriales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
EH2_k127_1350804_1	582744.Msip34_1318	7.367e-81	275.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,2KMEH@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH2_k127_1378099_1	1123368.AUIS01000003_gene1735	2.061e-70	254.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1SYRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
EH2_k127_1378099_0	1123368.AUIS01000003_gene1736	6.026e-105	356.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1RYS4@1236|Gammaproteobacteria,2NC0F@225057|Acidithiobacillales	225057|Acidithiobacillales	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_1378099_2	292415.Tbd_2395	1.323e-53	190.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,1KT6W@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
EH2_k127_1378099_3	1485544.JQKP01000012_gene2145	2.78e-23	100.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
EH2_k127_1393891_1	880072.Desac_2852	2.22e-25	107.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
EH2_k127_1393891_0	323848.Nmul_A1749	1.732e-156	507.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,3720B@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
EH2_k127_1393891_2	519989.ECTPHS_08343	2.923e-19	92.0	COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1WYRU@135613|Chromatiales	135613|Chromatiales	T	PFAM Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
EH2_k127_1399120_2	323848.Nmul_A0719	3.02e-48	177.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,372KA@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
EH2_k127_1399120_1	395494.Galf_1366	1.419e-199	629.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,44V10@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH2_k127_1399120_0	1163617.SCD_n01926	9.162e-278	863.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
EH2_k127_1465396_1	870187.Thini_2438	1.51e-170	542.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,463PR@72273|Thiotrichales	72273|Thiotrichales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH2_k127_1465396_7	1123399.AQVE01000001_gene754	1.007e-46	170.0	COG3162@1|root,COG3162@2|Bacteria,1N9T2@1224|Proteobacteria,1SSS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
EH2_k127_1465396_5	1123487.KB892857_gene2442	1.748e-78	267.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,2KUBI@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_1465396_4	543728.Vapar_6289	7.207e-98	336.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2WHKM@28216|Betaproteobacteria,4AJZE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH2_k127_1465396_3	1163617.SCD_n00481	4.939e-148	483.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
EH2_k127_1465396_6	1123400.KB904755_gene2631	1.734e-47	182.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH2_k127_1465396_2	314345.SPV1_12415	4.438e-151	491.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria	1224|Proteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH2_k127_1465396_0	85643.Tmz1t_4070	3.427e-225	707.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2WGIZ@28216|Betaproteobacteria,2KZPP@206389|Rhodocyclales	206389|Rhodocyclales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
EH2_k127_1465396_8	1286631.X805_41660	4.098e-36	141.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,1KJ5W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
EH2_k127_1483365_0	1123392.AQWL01000006_gene718	8.422e-140	451.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,1KSJ3@119069|Hydrogenophilales	119069|Hydrogenophilales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1483365_1	292415.Tbd_2538	2.005e-114	376.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2WA3C@28216|Betaproteobacteria,1KRW5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
EH2_k127_1483365_2	1123487.KB892846_gene512	8.925e-41	158.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
EH2_k127_1494706_0	1163617.SCD_n01259	4.225e-277	861.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH2_k127_1494706_1	1132855.KB913035_gene966	5.082e-56	197.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,2KMYK@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM ferredoxin, 2Fe-2S type, ISC system	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
EH2_k127_1494706_3	292415.Tbd_1170	5.665e-28	113.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,1KTDJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Iron-sulphur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
EH2_k127_1506701_1	640081.Dsui_1650	4.826e-53	192.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KU93@206389|Rhodocyclales	206389|Rhodocyclales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
EH2_k127_1506701_0	640081.Dsui_1973	4.653e-135	445.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,2KV42@206389|Rhodocyclales	206389|Rhodocyclales	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
EH2_k127_1520065_3	1163617.SCD_n01166	3.698e-35	138.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_1520065_1	335283.Neut_2178	6.097e-88	298.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,37229@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
EH2_k127_1520065_0	1123392.AQWL01000008_gene1171	3.937e-105	356.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,1KSI8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
EH2_k127_1520065_2	314278.NB231_16708	9.122e-74	253.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
EH2_k127_1566347_0	1198452.Jab_2c32490	2.606e-80	277.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,473CS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
EH2_k127_1566347_1	1266908.AQPB01000043_gene1424	8.953e-59	227.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,1RYHZ@1236|Gammaproteobacteria,1X0DU@135613|Chromatiales	135613|Chromatiales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD
EH2_k127_1566347_2	713587.THITH_13835	1.711e-34	134.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1WY21@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
EH2_k127_1579319_1	748247.AZKH_2881	1.808e-74	254.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,2KVC2@206389|Rhodocyclales	206389|Rhodocyclales	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_1579319_2	1163617.SCD_n01525	1.48e-40	164.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM Type IV pilus assembly PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
EH2_k127_1579319_0	1097668.BYI23_A012480	1.008e-76	271.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,1K0JG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
EH2_k127_1579319_3	94624.Bpet2504	3.91e-12	67.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,3T3YF@506|Alcaligenaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
EH2_k127_1580253_3	640081.Dsui_3387	1.035e-62	225.0	COG3447@1|root,COG4191@1|root,COG3447@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJUT@28216|Betaproteobacteria,2KYIQ@206389|Rhodocyclales	206389|Rhodocyclales	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
EH2_k127_1580253_4	640081.Dsui_3386	3.341e-53	205.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VSCC@28216|Betaproteobacteria,2KYUB@206389|Rhodocyclales	206389|Rhodocyclales	K	Flagellar regulatory protein FleQ	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH2_k127_1580253_0	1236959.BAMT01000005_gene199	1.011e-170	542.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,2KKC8@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
EH2_k127_1580253_5	935839.JAGJ01000004_gene2048	1.222e-13	81.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
EH2_k127_1580253_1	292415.Tbd_2815	3.788e-160	524.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KS5H@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
EH2_k127_1580253_2	243365.CV_0988	3.143e-98	326.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,2KPW1@206351|Neisseriales	206351|Neisseriales	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
EH2_k127_1604352_1	1163617.SCD_n00001	3.981e-157	501.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
EH2_k127_1604352_2	62928.azo0002	2.846e-118	390.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KV12@206389|Rhodocyclales	206389|Rhodocyclales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
EH2_k127_1604352_0	292415.Tbd_0003	0.0	1233.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,1KS2W@119069|Hydrogenophilales	119069|Hydrogenophilales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
EH2_k127_1604352_4	1123368.AUIS01000010_gene2357	8.322e-68	233.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,2NCV9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
EH2_k127_1604352_3	886293.Sinac_0152	3.726e-73	255.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_1623089_2	1123393.KB891330_gene892	1.783e-168	535.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2VSIQ@28216|Betaproteobacteria,1KRWA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
EH2_k127_1623089_1	159087.Daro_0080	2.923e-169	535.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VMK8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
EH2_k127_1623089_0	1123393.KB891330_gene890	2.93e-172	542.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter	cmpD_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
EH2_k127_1623089_3	1123393.KB891330_gene889	1.313e-137	465.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2VK37@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
EH2_k127_1623089_4	1123393.KB891330_gene888	9.254e-110	359.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VJ0X@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
EH2_k127_1628298_0	522306.CAP2UW1_1047	2.057e-195	636.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,1KQAW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4131)	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
EH2_k127_1628298_2	1121035.AUCH01000001_gene1940	5.053e-41	164.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,2KW1R@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
EH2_k127_1628298_1	1158756.AQXQ01000012_gene2031	2.757e-93	316.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
EH2_k127_1628298_3	1123392.AQWL01000004_gene2623	2.655e-18	86.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH2_k127_1632391_7	1123393.KB891317_gene2385	1.031e-18	90.0	COG3118@1|root,COG3118@2|Bacteria,1NWGI@1224|Proteobacteria,2W360@28216|Betaproteobacteria,1KRY1@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_1632391_3	748280.NH8B_3711	4.601e-48	181.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,2KR2Z@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
EH2_k127_1632391_2	292415.Tbd_1651	6.039e-80	273.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
EH2_k127_1632391_1	1163617.SCD_n01886	1.398e-104	344.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
EH2_k127_1632391_4	243365.CV_1990	2.715e-26	111.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,2KU19@206351|Neisseriales	206351|Neisseriales	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
EH2_k127_1632391_5	1123393.KB891316_gene1139	4.088e-26	110.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,1KTBG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
EH2_k127_1632391_0	292415.Tbd_1855	9.964e-223	702.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KS1V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
EH2_k127_1632391_6	323848.Nmul_A2653	1.575e-23	102.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,371XT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
EH2_k127_1635283_1	522306.CAP2UW1_1134	2.023e-95	328.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_1635283_0	85643.Tmz1t_4080	1.372e-179	567.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,2KV0I@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
EH2_k127_1635283_2	1123392.AQWL01000002_gene1810	1.301e-40	152.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1676199_2	1123393.KB891327_gene289	7.156e-10	62.0	COG3449@1|root,COG3449@2|Bacteria,1N79X@1224|Proteobacteria,2VWWR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1676199_0	292415.Tbd_1041	2.867e-112	372.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_1676199_1	631362.Thi970DRAFT_04780	5.109e-28	117.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WWXC@135613|Chromatiales	135613|Chromatiales	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH2_k127_1702292_3	983917.RGE_00300	4.487e-05	45.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1702292_1	572477.Alvin_0005	7.869e-60	219.0	2AJGQ@1|root,31A34@2|Bacteria,1NDT9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1702292_0	1384056.N787_13640	1.678e-86	302.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
EH2_k127_1702292_2	572477.Alvin_2655	1.001e-34	136.0	COG4932@1|root,COG4932@2|Bacteria,1NHC4@1224|Proteobacteria,1SUN7@1236|Gammaproteobacteria,1X207@135613|Chromatiales	135613|Chromatiales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
EH2_k127_1752573_3	1454004.AW11_03033	1.005e-55	199.0	COG4943@1|root,COG4943@2|Bacteria,1REXW@1224|Proteobacteria,2W323@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
EH2_k127_1752573_0	261292.Nit79A3_1229	3.19e-125	407.0	COG3568@1|root,COG3568@2|Bacteria,1R99W@1224|Proteobacteria,2VPVB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH2_k127_1752573_1	292415.Tbd_0750	2.609e-103	344.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,1KSTM@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp33 protein	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
EH2_k127_1752573_2	557598.LHK_00957	8.11e-74	266.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,2KU48@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
EH2_k127_1754601_2	1366050.N234_14350	1.73e-27	114.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,2WFVC@28216|Betaproteobacteria,1KI6J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
EH2_k127_1754601_0	522306.CAP2UW1_1003	0.0	1451.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KR73@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
EH2_k127_1754601_1	1123393.KB891316_gene1774	2.25e-131	424.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KRN6@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH2_k127_1775198_1	1123368.AUIS01000017_gene2573	8.749e-114	383.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,2NC30@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
EH2_k127_1775198_0	640081.Dsui_1456	2.999e-196	638.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,2KVJ8@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	FHA,GAF,HD,HD_5
EH2_k127_1775198_2	272624.lpg0056	3.252e-24	105.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,1SNN0@1236|Gammaproteobacteria,1JDTQ@118969|Legionellales	118969|Legionellales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
EH2_k127_1775856_0	207559.Dde_3114	2.352e-141	463.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2WJJ9@28221|Deltaproteobacteria,2M8RX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
EH2_k127_1775856_1	1121447.JONL01000008_gene3610	1.953e-82	305.0	COG4191@1|root,COG4564@1|root,COG5000@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions,2WJVA@28221|Deltaproteobacteria,2M8BT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,NMT1,PAS_3,PAS_4,Response_reg,dCache_1,sCache_2
EH2_k127_1775856_2	1123368.AUIS01000019_gene1219	4.257e-52	211.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
EH2_k127_1775856_3	713586.KB900536_gene1636	1.114e-33	142.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1775856_4	1232427.CAVS020000015_gene577	4.17e-10	65.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,22K7I@1653|Corynebacteriaceae	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
EH2_k127_1782230_2	292415.Tbd_0827	8.912e-123	398.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria,1KSG7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH2_k127_1782230_0	395494.Galf_0008	3.024e-188	595.0	COG2301@1|root,COG2301@2|Bacteria,1PCZW@1224|Proteobacteria,2W07M@28216|Betaproteobacteria	28216|Betaproteobacteria	G	HpcH HpaI aldolase	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
EH2_k127_1782230_1	395494.Galf_0009	3.132e-179	569.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
EH2_k127_1782679_1	1122603.ATVI01000006_gene775	6.975e-45	170.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_1782679_2	515635.Dtur_1814	1.461e-44	170.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_1782679_0	1121035.AUCH01000022_gene3204	4.029e-84	294.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2W0B5@28216|Betaproteobacteria,2KXXD@206389|Rhodocyclales	206389|Rhodocyclales	S	Sugar fermentation stimulation protein	-	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
EH2_k127_180725_4	62928.azo3458	3.153e-111	378.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KUA4@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
EH2_k127_180725_6	1123392.AQWL01000006_gene674	7.701e-74	268.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,1KRQ7@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
EH2_k127_180725_10	1123487.KB892834_gene2868	2.373e-39	159.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,2KWP7@206389|Rhodocyclales	206389|Rhodocyclales	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
EH2_k127_180725_8	1123393.KB891316_gene1951	1.351e-52	191.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,1KSC9@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosyl transferase domain	-	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
EH2_k127_180725_3	1123392.AQWL01000006_gene671	4.456e-154	492.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1KSA3@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH2_k127_180725_1	1123392.AQWL01000006_gene670	5.671e-186	606.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KS69@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH2_k127_180725_5	292415.Tbd_0519	1.573e-93	314.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_180725_2	292415.Tbd_0616	6.677e-181	589.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_180725_9	1163617.SCD_n01942	1.708e-42	166.0	COG2203@1|root,COG2203@2|Bacteria,1RG7F@1224|Proteobacteria,2VUF7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
EH2_k127_180725_7	265072.Mfla_2479	3.63e-66	239.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KMKC@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
EH2_k127_180725_0	1123393.KB891316_gene1772	0.0	1018.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,1KSEV@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
EH2_k127_180725_11	62928.azo2878	1.949e-05	49.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,2KWYJ@206389|Rhodocyclales	206389|Rhodocyclales	O	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
EH2_k127_1810273_4	1415779.JOMH01000001_gene987	1.28e-14	76.0	2DEFP@1|root,2ZMU8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1810273_0	279714.FuraDRAFT_2839	5.012e-119	386.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,2KQDR@206351|Neisseriales	206351|Neisseriales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
EH2_k127_1810273_2	1454004.AW11_01478	3.039e-38	151.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,1KQ4C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
EH2_k127_1810273_3	396588.Tgr7_0204	1.53e-33	134.0	COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria,1X1B8@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1810273_1	522306.CAP2UW1_1078	9.192e-66	228.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KQU5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
EH2_k127_181546_0	1163617.SCD_n02922	4.785e-142	463.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH2_k127_181546_1	1121035.AUCH01000006_gene765	4.07e-97	320.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
EH2_k127_1858466_0	1123393.KB891331_gene2919	8.051e-194	615.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
EH2_k127_1858466_4	1163617.SCD_n00983	1.139e-57	214.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
EH2_k127_1858466_2	640081.Dsui_0753	1.838e-162	515.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUDD@206389|Rhodocyclales	206389|Rhodocyclales	S	of ABC transporters with duplicated ATPase	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_1858466_3	1123487.KB892857_gene2425	2.031e-113	369.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUDD@206389|Rhodocyclales	206389|Rhodocyclales	S	of ABC transporters with duplicated ATPase	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_1858466_5	640081.Dsui_0249	2.824e-16	88.0	2CJFN@1|root,32ZIB@2|Bacteria,1N7QI@1224|Proteobacteria,2VX2C@28216|Betaproteobacteria,2KX8A@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_1858466_1	292415.Tbd_0104	9.063e-167	526.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,1KRXU@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
EH2_k127_1860828_0	582744.Msip34_1077	3.85e-144	479.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KM5A@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH2_k127_1860828_1	1196835.A458_10195	2.437e-110	376.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z0JB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH2_k127_1936434_0	1163617.SCD_n00794	3.01e-226	706.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_1936434_1	1123392.AQWL01000008_gene1162	1.956e-61	212.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
EH2_k127_1956704_1	1123393.KB891327_gene425	1.26e-23	102.0	COG2204@1|root,COG2204@2|Bacteria,1QVPI@1224|Proteobacteria,2WHXV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16
EH2_k127_1956704_0	292415.Tbd_1568	0.0	1071.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1KRI7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
EH2_k127_2025022_1	1123392.AQWL01000002_gene2049	1.18e-92	313.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,1KSX5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
EH2_k127_2025022_0	292415.Tbd_0315	5.789e-153	488.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1KS1S@119069|Hydrogenophilales	119069|Hydrogenophilales	E	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
EH2_k127_2044418_2	1249627.D779_0042	4.963e-44	173.0	COG3259@1|root,COG3259@2|Bacteria,1RFVW@1224|Proteobacteria,1T354@1236|Gammaproteobacteria,1X2UT@135613|Chromatiales	135613|Chromatiales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
EH2_k127_2044418_0	1304883.KI912532_gene2365	0.0	1117.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,2KUXJ@206389|Rhodocyclales	206389|Rhodocyclales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
EH2_k127_2044418_1	1304883.KI912532_gene2366	9.145e-177	557.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
EH2_k127_205795_0	1121004.ATVC01000007_gene1109	5.289e-164	520.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KPHF@206351|Neisseriales	206351|Neisseriales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
EH2_k127_205795_4	1163617.SCD_n01253	7.868e-62	217.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Iron-sulfur cluster assembly transcription factor IscR	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
EH2_k127_205795_2	292415.Tbd_1162	1.695e-118	385.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,1KSH1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
EH2_k127_205795_3	1163617.SCD_n01251	2.084e-67	237.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
EH2_k127_205795_1	1236959.BAMT01000001_gene1097	2.205e-121	400.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KKRI@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
EH2_k127_2105816_1	1538295.JY96_00995	2.109e-115	380.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,1KJQP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
EH2_k127_2105816_0	640081.Dsui_1465	1.428e-213	674.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,2KVDZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
EH2_k127_2105816_2	795666.MW7_0758	1.538e-95	328.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,1K50V@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
EH2_k127_2105816_3	536232.CLM_0129	9.737e-23	100.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_2120482_4	1249627.D779_0042	1.803e-25	110.0	COG3259@1|root,COG3259@2|Bacteria,1RFVW@1224|Proteobacteria,1T354@1236|Gammaproteobacteria,1X2UT@135613|Chromatiales	135613|Chromatiales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
EH2_k127_2120482_2	266264.Rmet_1535	9.587e-41	157.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VUFZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
EH2_k127_2120482_1	640081.Dsui_1163	5.578e-137	443.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,2KUUA@206389|Rhodocyclales	206389|Rhodocyclales	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
EH2_k127_2120482_0	266264.Rmet_1537	5.518e-317	988.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1K2HP@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF2	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Carbam_trans_N,Sua5_yciO_yrdC,zf-HYPF
EH2_k127_2120482_5	640081.Dsui_1160	2.813e-24	112.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,2KX70@206389|Rhodocyclales	206389|Rhodocyclales	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH2_k127_2120482_3	640081.Dsui_1159	1.582e-29	123.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,2KVMG@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
EH2_k127_2137777_1	395494.Galf_1985	7.074e-54	197.0	2CMG5@1|root,32SEP@2|Bacteria,1N1C2@1224|Proteobacteria,2W882@28216|Betaproteobacteria,44WI5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2137777_2	1121035.AUCH01000014_gene2406	2.326e-45	172.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2WEG6@28216|Betaproteobacteria,2KW5A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	cc43	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH2_k127_2137777_0	1123393.KB891327_gene394	5e-324	1013.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,1KRJ3@119069|Hydrogenophilales	119069|Hydrogenophilales	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
EH2_k127_2137777_3	1049564.TevJSym_ad00410	7.906e-40	154.0	2E8HY@1|root,332W0@2|Bacteria,1N9SS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2151831_1	76114.ebA5117	1.206e-37	149.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,2KUPR@206389|Rhodocyclales	206389|Rhodocyclales	T	alginate biosynthesis protein AlgZ FimS	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
EH2_k127_2151831_0	1163617.SCD_n02121	1.532e-103	348.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria	1224|Proteobacteria	E	D-Amino acid dehydrogenase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
EH2_k127_2153052_7	1144319.PMI16_05050	1.838e-36	147.0	COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,2VR22@28216|Betaproteobacteria,476UN@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
EH2_k127_2153052_8	62928.azo2294	2.217e-29	121.0	COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,2VJH0@28216|Betaproteobacteria,2KY5D@206389|Rhodocyclales	206389|Rhodocyclales	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
EH2_k127_2153052_4	1144319.PMI16_05051	7.498e-100	334.0	COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,2VJH0@28216|Betaproteobacteria,475CG@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
EH2_k127_2153052_3	1123392.AQWL01000012_gene2460	6.32e-122	398.0	COG1028@1|root,COG1028@2|Bacteria	1123392.AQWL01000012_gene2460|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2153052_1	395495.Lcho_2507	1.025e-149	497.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,1KJ7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
EH2_k127_2153052_2	1123392.AQWL01000001_gene1436	1.727e-124	412.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
EH2_k127_2153052_10	243233.MCA0659	2.686e-20	94.0	COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,1SJ0H@1236|Gammaproteobacteria,1XFAC@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
EH2_k127_2153052_0	1163617.SCD_n00482	9.518e-196	625.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,2VZP7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
EH2_k127_2153052_6	1163617.SCD_n00483	8.142e-52	185.0	COG0347@1|root,COG0347@2|Bacteria,1RF4Q@1224|Proteobacteria,2W3NK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
EH2_k127_2153052_9	1163617.SCD_n00484	2.864e-27	115.0	2DZHF@1|root,33JTD@2|Bacteria,1R3DF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2153052_5	640511.BC1002_5982	2.562e-58	209.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,2VN09@28216|Betaproteobacteria,1K3TX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
EH2_k127_2172905_3	1123393.KB891326_gene130	2.098e-22	97.0	COG0298@1|root,COG0298@2|Bacteria,1PWRZ@1224|Proteobacteria,2WCAT@28216|Betaproteobacteria,1KTC5@119069|Hydrogenophilales	119069|Hydrogenophilales	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
EH2_k127_2172905_0	543728.Vapar_1354	8.827e-76	259.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,4AFNW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
EH2_k127_2172905_4	580332.Slit_0451	6.559e-16	81.0	2CHG9@1|root,3332K@2|Bacteria,1NCD5@1224|Proteobacteria,2VWRB@28216|Betaproteobacteria,44W1I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2172905_2	522306.CAP2UW1_1027	1.286e-54	206.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
EH2_k127_2172905_1	292415.Tbd_0886	7.199e-56	209.0	COG3118@1|root,COG3118@2|Bacteria,1NWGI@1224|Proteobacteria,2W360@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Tetratricopeptide repeat	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_2174324_0	572477.Alvin_2880	8.566e-176	564.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,1S0Z6@1236|Gammaproteobacteria,1WXDJ@135613|Chromatiales	135613|Chromatiales	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_2174324_1	1095769.CAHF01000009_gene1397	5.961e-162	516.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
EH2_k127_2174324_2	1123392.AQWL01000007_gene876	7.026e-124	399.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KSMU@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_2174324_3	292415.Tbd_1582	2.062e-33	132.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH2_k127_2174401_4	1120999.JONM01000004_gene3547	1.785e-31	125.0	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,2VW65@28216|Betaproteobacteria,2KRZK@206351|Neisseriales	206351|Neisseriales	S	Pathogenicity locus	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
EH2_k127_2174401_1	338969.Rfer_0862	1.104e-74	255.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,4AGUW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
EH2_k127_2174401_6	765911.Thivi_4360	1.161e-22	105.0	28K7D@1|root,2Z9VI@2|Bacteria,1R8BZ@1224|Proteobacteria,1S0U2@1236|Gammaproteobacteria,1WXW5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2174401_2	85643.Tmz1t_3867	3.591e-63	226.0	COG3713@1|root,COG3713@2|Bacteria,1N0BC@1224|Proteobacteria,2WAUT@28216|Betaproteobacteria,2KZMR@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
EH2_k127_2174401_0	338966.Ppro_0408	2.598e-90	310.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2174401_5	314278.NB231_07442	4.03e-23	104.0	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2178533_1	1163617.SCD_n01211	6.943e-92	308.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
EH2_k127_2178533_0	748247.AZKH_2805	9.017e-110	366.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_2191033_3	572477.Alvin_0689	1.3e-07	53.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1S6B0@1236|Gammaproteobacteria,1WYPJ@135613|Chromatiales	135613|Chromatiales	P	PFAM Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
EH2_k127_2191033_1	1000565.METUNv1_03020	3.748e-83	290.0	COG1566@1|root,COG1566@2|Bacteria,1QW95@1224|Proteobacteria,2WI8S@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH2_k127_2191033_0	365044.Pnap_0081	1.026e-116	390.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2VHS2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH2_k127_2191033_2	316055.RPE_3952	1.665e-44	164.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,3JWVM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD1	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
EH2_k127_2210843_1	1163617.SCD_n02085	4.768e-33	133.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,2W4VG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2210843_0	62928.azo0095	2.564e-285	888.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
EH2_k127_2213293_4	1132855.KB913035_gene475	2.741e-13	71.0	COG3203@1|root,COG3203@2|Bacteria,1PJNW@1224|Proteobacteria,2VJS1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
EH2_k127_2213293_1	1485544.JQKP01000002_gene1464	1.058e-250	802.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS,PAS_4,dCache_3
EH2_k127_2213293_0	292415.Tbd_1078	2.023e-263	825.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,1KRBU@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
EH2_k127_2213293_3	1123393.KB891327_gene427	1.372e-35	138.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria,1KTBC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2213293_2	1198452.Jab_2c19640	2.967e-199	642.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria,475G7@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
EH2_k127_2237348_4	1158292.JPOE01000002_gene1673	7.383e-20	90.0	2AE70@1|root,32VN7@2|Bacteria,1N3TT@1224|Proteobacteria,2VVAV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2237348_3	1123393.KB891316_gene1967	9.234e-44	163.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,2VUQQ@28216|Betaproteobacteria,1KT2W@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
EH2_k127_2237348_1	1366050.N234_35140	1.682e-97	329.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,1K3UW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Chromate resistance	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH2_k127_2237348_0	1123392.AQWL01000006_gene608	5.07e-224	701.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1KRYZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
EH2_k127_2237348_2	596154.Alide2_1763	8.078e-63	218.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,4ADCX@80864|Comamonadaceae	28216|Betaproteobacteria	P	Superoxide dismutase	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Sod_Fe_C
EH2_k127_2265155_2	1123392.AQWL01000008_gene1190	2.171e-110	362.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1KRBX@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Sec-independent protein translocase protein (TatC)	-	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
EH2_k127_2265155_9	62928.azo3339	1.335e-22	103.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH2_k127_2265155_8	292415.Tbd_1704	1.054e-22	99.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KTFE@119069|Hydrogenophilales	119069|Hydrogenophilales	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
EH2_k127_2265155_6	1163617.SCD_n00594	4.391e-53	188.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
EH2_k127_2265155_7	1163617.SCD_n00593	1.153e-42	160.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
EH2_k127_2265155_5	1485544.JQKP01000011_gene771	2.019e-62	226.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
EH2_k127_2265155_0	266265.Bxe_A0404	2.026e-131	426.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1K0MT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH2_k127_2265155_1	1122236.KB905143_gene16	1.883e-127	424.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KKGM@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
EH2_k127_2265155_4	1123392.AQWL01000008_gene1198	5.799e-91	308.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,1KSGP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
EH2_k127_2265155_3	1123393.KB891329_gene973	4.535e-105	346.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,1KRGQ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
EH2_k127_2265155_10	1123392.AQWL01000008_gene1200	5.769e-20	97.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,1KRD6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_2275024_2	85643.Tmz1t_1861	1.403e-54	199.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,2KWAK@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome B561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
EH2_k127_2275024_0	1123368.AUIS01000010_gene2378	6.415e-105	349.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	yeeY	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_2275024_1	292415.Tbd_1285	4.936e-91	303.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,1KRYE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	TOBE domain	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
EH2_k127_2275743_2	292415.Tbd_0079	1.693e-45	171.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VTXX@28216|Betaproteobacteria,1KTD7@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Crp-like helix-turn-helix domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_2275743_3	1266925.JHVX01000002_gene893	4.72e-34	135.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,373I3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
EH2_k127_2275743_0	1163617.SCD_n01127	5.854e-231	719.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_2275743_1	497321.C664_06623	7.106e-202	634.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KV2B@206389|Rhodocyclales	206389|Rhodocyclales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
EH2_k127_2280677_1	1101195.Meth11DRAFT_1593	9.11e-90	297.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,2KKXM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH2_k127_2280677_3	1123261.AXDW01000001_gene1332	1.816e-73	258.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X97T@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
EH2_k127_2280677_7	1349767.GJA_422	3.215e-46	181.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,473MP@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
EH2_k127_2280677_5	62928.azo3822	5.163e-58	205.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,2KWU9@206389|Rhodocyclales	206389|Rhodocyclales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
EH2_k127_2280677_0	1123393.KB891331_gene2844	3.31e-158	506.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,1KRVI@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
EH2_k127_2280677_4	265072.Mfla_0204	4.072e-58	209.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,2KKKA@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM DnaA regulatory inactivator Hda	-	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
EH2_k127_2280677_2	1304883.KI912532_gene615	1.648e-75	266.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,2KXTJ@206389|Rhodocyclales	206389|Rhodocyclales	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2280677_6	396588.Tgr7_2426	1.262e-49	179.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria,1WYEG@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
EH2_k127_2280677_8	1123392.AQWL01000002_gene1977	1.386e-05	53.0	2AFZ2@1|root,3162V@2|Bacteria,1PWRF@1224|Proteobacteria,2WCA6@28216|Betaproteobacteria,1KTB4@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2281336_0	1485544.JQKP01000001_gene1311	1.509e-154	500.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,44V5V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
EH2_k127_231372_1	76114.ebA3993	1.44e-118	396.0	COG0515@1|root,COG0515@2|Bacteria,1R47Q@1224|Proteobacteria,2WGQS@28216|Betaproteobacteria,2KVBN@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH2_k127_231372_0	76114.ebA3997	1.334e-166	530.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,2KVC8@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_231372_2	76114.ebA3998	8.938e-37	139.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_2319977_1	1123392.AQWL01000004_gene2564	1.243e-99	340.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria,1KRTJ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
EH2_k127_2319977_0	1123392.AQWL01000004_gene2563	1.44e-153	498.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KRAB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
EH2_k127_2319977_3	1304883.KI912532_gene2486	4.723e-31	136.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,2KWUE@206389|Rhodocyclales	206389|Rhodocyclales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
EH2_k127_2319977_2	580332.Slit_1234	8.236e-58	209.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
EH2_k127_2335740_3	292415.Tbd_0566	7.989e-34	133.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1KT0V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH2_k127_2335740_5	765911.Thivi_1665	5.51e-18	89.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria,1WZIE@135613|Chromatiales	135613|Chromatiales	CO	TIGRFAM small redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
EH2_k127_2335740_4	292415.Tbd_1429	2.236e-29	130.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
EH2_k127_2335740_1	1123392.AQWL01000008_gene1246	1.931e-124	404.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
EH2_k127_2335740_2	1163617.SCD_n02153	1.215e-34	142.0	2EENH@1|root,338GC@2|Bacteria,1N9EC@1224|Proteobacteria,2W4GB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2335740_0	292415.Tbd_1427	4.443e-140	447.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VJC7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
EH2_k127_2368058_2	1123393.KB891317_gene2312	5.952e-56	197.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,1KSC2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
EH2_k127_2368058_1	1123393.KB891317_gene2313	1.115e-150	481.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1KREP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
EH2_k127_2368058_3	265072.Mfla_1831	1.123e-54	202.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VYPK@28216|Betaproteobacteria,2KMQ0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
EH2_k127_2368058_4	1123392.AQWL01000004_gene2717	2.986e-39	151.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,1KRWE@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase III chi subunit, HolC	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol3_chi
EH2_k127_2368058_0	292415.Tbd_0577	0.0	1418.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,1KRA3@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Valyl tRNA synthetase tRNA binding arm	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH2_k127_2383137_10	159087.Daro_1560	7.678e-11	66.0	2EI92@1|root,33C0E@2|Bacteria,1NHN6@1224|Proteobacteria,2VYC9@28216|Betaproteobacteria,2KXI8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2383137_11	272568.GDI1958	0.0001598	51.0	28Y9S@1|root,2ZK4K@2|Bacteria,1P5V2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2383137_4	1123368.AUIS01000033_gene1378	6.157e-99	329.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Pseudouridine synthase	truC	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
EH2_k127_2383137_6	1335757.SPICUR_01905	3.238e-29	120.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,1SDJI@1236|Gammaproteobacteria,1WZBJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
EH2_k127_2383137_5	62928.azo2126	1.365e-80	272.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,2KWB4@206389|Rhodocyclales	206389|Rhodocyclales	S	YaeQ family	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
EH2_k127_2383137_7	1163617.SCD_n01361	3.312e-23	104.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,2VVQY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RNA-binding	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
EH2_k127_2383137_0	159087.Daro_1444	1.276e-274	854.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,2KXHK@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_2383137_1	742823.HMPREF9465_00614	9.905e-258	803.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,4PQH6@995019|Sutterellaceae	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
EH2_k127_2383137_9	509190.Cseg_3398	2.07e-14	84.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH2_k127_2383137_8	1304883.KI912532_gene2637	1.217e-17	84.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VW0H@28216|Betaproteobacteria,2KXHW@206389|Rhodocyclales	206389|Rhodocyclales	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
EH2_k127_2383137_2	1163617.SCD_n01376	1.298e-121	404.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
EH2_k127_2383137_3	1502770.JQMG01000001_gene65	9.488e-108	357.0	28IX1@1|root,2ZC5T@2|Bacteria,1R35E@1224|Proteobacteria,2VQUH@28216|Betaproteobacteria,2KKKU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
EH2_k127_2384787_0	1123393.KB891316_gene1588	2.803e-205	646.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,1KSRT@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
EH2_k127_2384787_3	1190603.AJYD01000041_gene2640	6.049e-10	68.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1XXSJ@135623|Vibrionales	135623|Vibrionales	C	COG2863 Cytochrome c553	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH2_k127_2384787_2	330214.NIDE0437	6.664e-26	116.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
EH2_k127_2384787_1	159087.Daro_1851	4.465e-45	166.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
EH2_k127_2405192_0	1163617.SCD_n02082	0.0	1035.0	COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,2VJ7F@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
EH2_k127_2405192_1	1123393.KB891316_gene1807	8.199e-163	519.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1KS77@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Coproporphyrinogen III oxidase	-	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
EH2_k127_2405192_2	243365.CV_0550	2.537e-61	218.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,2KR4H@206351|Neisseriales	206351|Neisseriales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
EH2_k127_2405192_3	1485544.JQKP01000002_gene1438	2.725e-06	49.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,44V8B@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
EH2_k127_2407081_2	1163617.SCD_n00765	3.45e-49	182.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Hydrogenase expression formation protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
EH2_k127_2407081_3	1123392.AQWL01000002_gene1749	2.736e-23	110.0	COG2827@1|root,COG2827@2|Bacteria,1PWU4@1224|Proteobacteria,2WCCX@28216|Betaproteobacteria,1KTFS@119069|Hydrogenophilales	119069|Hydrogenophilales	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
EH2_k127_2407081_0	331678.Cphamn1_1902	4.563e-177	567.0	COG1109@1|root,COG1109@2|Bacteria,1FEY1@1090|Chlorobi	1090|Chlorobi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_2407081_1	640511.BC1002_5982	6.515e-103	345.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,2VN09@28216|Betaproteobacteria,1K3TX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
EH2_k127_2448085_1	1123393.KB891316_gene1119	1.123e-20	94.0	COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria,1KSAM@119069|Hydrogenophilales	119069|Hydrogenophilales	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2448085_0	497321.C664_02615	2.82e-180	584.0	COG0308@1|root,COG0308@2|Bacteria,1PVVK@1224|Proteobacteria,2VIU3@28216|Betaproteobacteria,2KY1X@206389|Rhodocyclales	206389|Rhodocyclales	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
EH2_k127_2451010_0	1221522.B723_16310	6.63e-169	536.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1YS5T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_2451010_1	1454004.AW11_02632	3.036e-130	425.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
EH2_k127_2451010_3	1162668.LFE_1603	3.287e-10	68.0	2E1KM@1|root,32WY3@2|Bacteria	2|Bacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	EthD
EH2_k127_2451010_2	1283300.ATXB01000001_gene391	4.862e-33	131.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria	1224|Proteobacteria	O	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
EH2_k127_2470819_6	1123392.AQWL01000001_gene1357	1.47e-47	172.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase, U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
EH2_k127_2470819_2	1123368.AUIS01000007_gene2814	9.348e-129	425.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
EH2_k127_2470819_3	1123392.AQWL01000004_gene2679	8.737e-94	322.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KSC3@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_2470819_9	338963.Pcar_2627	2.472e-26	113.0	2EHUK@1|root,33BK8@2|Bacteria,1Q1PA@1224|Proteobacteria,437D9@68525|delta/epsilon subdivisions,2X2JB@28221|Deltaproteobacteria,43VPA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2470819_7	187303.BN69_3369	4.902e-33	134.0	2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,370RI@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
EH2_k127_2470819_0	1163617.SCD_n02380	2.541e-225	707.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polyphosphate kinase	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
EH2_k127_2470819_8	1123401.JHYQ01000001_gene1831	1.485e-32	127.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
EH2_k127_2470819_4	1123393.KB891316_gene1317	1.759e-92	307.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,1KSU1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Rnf-Nqr subunit, membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
EH2_k127_2470819_5	395494.Galf_2364	1.012e-83	291.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
EH2_k127_2470819_1	1123392.AQWL01000001_gene1457	2.342e-187	599.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,1KSZA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,RnfC_N,SLBB
EH2_k127_2486956_1	342113.DM82_2513	5.381e-61	215.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1K1TA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
EH2_k127_2486956_3	768671.ThimaDRAFT_3514	6.167e-12	70.0	2BVMS@1|root,2ZD7A@2|Bacteria,1P839@1224|Proteobacteria,1STHW@1236|Gammaproteobacteria,1X1K8@135613|Chromatiales	135613|Chromatiales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2486956_0	1163617.SCD_n01212	5.457e-109	361.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VKS0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_2486956_2	1123368.AUIS01000001_gene2062	6.649e-61	228.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
EH2_k127_2491498_0	1123392.AQWL01000011_gene2217	1.206e-145	468.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KREY@119069|Hydrogenophilales	119069|Hydrogenophilales	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH2_k127_2491498_1	497321.C664_03570	5.232e-87	294.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KUEU@206389|Rhodocyclales	206389|Rhodocyclales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
EH2_k127_2491498_2	1158146.KB907121_gene1250	1.327e-05	53.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
EH2_k127_24916_3	582744.Msip34_2193	1.059e-73	248.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,2KMGG@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
EH2_k127_24916_2	1218074.BAXZ01000005_gene1253	5.506e-107	350.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1K0N1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
EH2_k127_24916_1	1123393.KB891316_gene1434	1.085e-142	456.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,1KS76@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
EH2_k127_24916_4	1123392.AQWL01000001_gene1349	1.051e-21	96.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
EH2_k127_24916_0	1123392.AQWL01000022_gene2175	1.629e-194	614.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,1KSWW@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
EH2_k127_2500756_1	1163617.SCD_n01949	6.031e-138	447.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
EH2_k127_2500756_0	1123393.KB891328_gene553	1.218e-157	504.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,1KRFC@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH2_k127_2514063_2	1123392.AQWL01000011_gene2233	5.082e-59	213.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_2514063_1	768671.ThimaDRAFT_0979	4.824e-68	238.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_2514063_3	1123367.C666_14735	2.544e-58	208.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,2KWEB@206389|Rhodocyclales	206389|Rhodocyclales	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
EH2_k127_2514063_4	1123392.AQWL01000002_gene1848	4.472e-46	174.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,1KRSA@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
EH2_k127_2514063_6	1120999.JONM01000007_gene1808	9.926e-31	126.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,2KRD8@206351|Neisseriales	206351|Neisseriales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
EH2_k127_2514063_0	1122951.ATUE01000006_gene1113	2.485e-139	449.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,3NNA6@468|Moraxellaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH2_k127_2514063_5	305700.B447_20945	6.027e-39	149.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH2_k127_2518603_0	237609.PSAKL28_25280	2.896e-201	640.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF2	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
EH2_k127_2518603_2	395495.Lcho_0484	2.336e-42	169.0	COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
EH2_k127_2518603_1	395495.Lcho_0484	5.539e-82	279.0	COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
EH2_k127_2554178_4	292415.Tbd_2183	2.23e-36	144.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria,1KRVF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
EH2_k127_2554178_2	1123393.KB891316_gene1496	1.964e-126	412.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria,1KRJJ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
EH2_k127_2554178_0	748247.AZKH_0483	1.682e-172	545.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
EH2_k127_2554178_1	1123392.AQWL01000005_gene2925	4.311e-131	431.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,2VI70@28216|Betaproteobacteria,1KT0A@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Radical_SAM C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
EH2_k127_2554178_5	1123255.JHYS01000007_gene1605	2.587e-29	119.0	COG4309@1|root,COG4309@2|Bacteria,1N4MS@1224|Proteobacteria,2VU7H@28216|Betaproteobacteria,4AEZS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
EH2_k127_2554178_3	870187.Thini_2588	6.615e-54	192.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_2554178_6	292415.Tbd_1406	4.006e-11	63.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2VK31@28216|Betaproteobacteria,1KRB6@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrate reductase gamma subunit	-	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
EH2_k127_2587523_1	1163617.SCD_n00905	4.371e-36	146.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_2587523_0	41431.PCC8801_1349	1.322e-72	273.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,3KGCP@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
EH2_k127_2596637_0	159087.Daro_1851	1.526e-269	838.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
EH2_k127_2596637_1	1121035.AUCH01000001_gene1816	6.226e-47	177.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria,2KW1T@206389|Rhodocyclales	206389|Rhodocyclales	T	ANTAR	-	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
EH2_k127_2596637_2	1121921.KB898710_gene619	3.089e-30	124.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,2PMN1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	nasA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_2608475_3	292415.Tbd_1403	2.158e-93	307.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2VJ2F@28216|Betaproteobacteria,1KRFS@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Respiratory nitrate reductase alpha N-terminal	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
EH2_k127_2608475_1	1450525.JATV01000002_gene2024	5.205e-142	470.0	COG2223@1|root,COG2223@2|Bacteria,4NJ57@976|Bacteroidetes,1HWYX@117743|Flavobacteriia,2NV1N@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,MgtE_N
EH2_k127_2608475_0	85643.Tmz1t_2637	4.154e-209	660.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,2KUQD@206389|Rhodocyclales	206389|Rhodocyclales	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
EH2_k127_2608475_2	1123392.AQWL01000003_gene153	1.447e-141	465.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KSZK@119069|Hydrogenophilales	119069|Hydrogenophilales	T	GAF domain	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_3,HAMP,HATPase_c,HisKA_3,PilJ
EH2_k127_2610746_0	1123393.KB891316_gene2084	0.0	1161.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1KRCT@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
EH2_k127_2610746_1	748280.NH8B_2959	1.178e-162	518.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,2KPWM@206351|Neisseriales	206351|Neisseriales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
EH2_k127_2631197_6	1000565.METUNv1_03021	3.413e-07	53.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2VHS2@28216|Betaproteobacteria,2KVZT@206389|Rhodocyclales	206389|Rhodocyclales	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
EH2_k127_2631197_2	1000565.METUNv1_03022	1.967e-91	306.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2WEGN@28216|Betaproteobacteria,2KVA1@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
EH2_k127_2631197_3	1163617.SCD_n00150	3.889e-59	211.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
EH2_k127_2631197_0	395493.BegalDRAFT_3046	3.95e-143	466.0	COG2010@1|root,COG2010@2|Bacteria,1RD0F@1224|Proteobacteria,1SPHI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
EH2_k127_2631197_1	1122236.KB905146_gene1896	1.705e-103	344.0	COG1305@1|root,COG1305@2|Bacteria,1MVAG@1224|Proteobacteria,2VMU5@28216|Betaproteobacteria,2KNMV@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
EH2_k127_2637177_3	580332.Slit_0513	2.009e-83	293.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria,44VIP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH2_k127_2637177_4	62928.azo0571	7.832e-71	244.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,2KW42@206389|Rhodocyclales	206389|Rhodocyclales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
EH2_k127_2637177_1	640081.Dsui_0489	1.016e-115	381.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,2KUG6@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
EH2_k127_2637177_0	1123393.KB891316_gene1685	5.086e-225	705.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1KRE8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
EH2_k127_2637177_5	1049564.TevJSym_ap00330	3.974e-48	176.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
EH2_k127_2637177_6	472759.Nhal_2244	1.627e-44	166.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria,1X0WB@135613|Chromatiales	135613|Chromatiales	J	PFAM Cold-shock protein, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
EH2_k127_2637177_2	522306.CAP2UW1_1170	2.522e-86	291.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_2637653_1	279714.FuraDRAFT_0396	1.006e-92	310.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KQDG@206351|Neisseriales	206351|Neisseriales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH2_k127_2637653_2	1123393.KB891331_gene2927	2.452e-69	244.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,1KT00@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_2637653_5	441620.Mpop_5133	0.0001689	46.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
EH2_k127_2637653_0	1158182.KB905021_gene524	1.852e-205	647.0	28IVT@1|root,2Z8U5@2|Bacteria,1R7G9@1224|Proteobacteria,1S02A@1236|Gammaproteobacteria,1WXJ0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2637653_4	1123368.AUIS01000006_gene619	1.299e-33	130.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2ND6Z@225057|Acidithiobacillales	225057|Acidithiobacillales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_2637653_3	395495.Lcho_1775	4.519e-50	183.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria,1KK0E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Helix-turn-helix type 11	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
EH2_k127_2654267_5	1304865.JAGF01000001_gene1516	0.0008146	43.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4F2SF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_2654267_3	1192868.CAIU01000033_gene4184	4.646e-49	182.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_2654267_2	1123392.AQWL01000002_gene1747	3.254e-61	220.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2W3S1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
EH2_k127_2654267_4	765911.Thivi_2536	5.499e-16	79.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,1WWJ7@135613|Chromatiales	135613|Chromatiales	P	PFAM C4-dicarboxylate transporter malic acid transport protein	-	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
EH2_k127_2654267_0	765912.Thimo_2611	1.192e-90	304.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,1WWJ7@135613|Chromatiales	135613|Chromatiales	P	PFAM C4-dicarboxylate transporter malic acid transport protein	-	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
EH2_k127_2654267_1	296591.Bpro_4278	1.082e-83	285.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_2710110_0	1485544.JQKP01000007_gene1951	1.543e-55	200.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,44VJV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
EH2_k127_2710110_1	1163617.SCD_n01642	2.402e-34	133.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,2VTYF@28216|Betaproteobacteria	28216|Betaproteobacteria	N	homolog of the cytoplasmic domain of flagellar protein FhlB	flhB_1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
EH2_k127_2710110_2	497321.C664_18739	1.255e-22	112.0	COG3144@1|root,COG3144@2|Bacteria,1N0CE@1224|Proteobacteria,2VQG2@28216|Betaproteobacteria,2KW7V@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
EH2_k127_2713958_1	395494.Galf_2353	6.474e-127	420.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,2VKQP@28216|Betaproteobacteria,44V12@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
EH2_k127_2713958_2	765913.ThidrDRAFT_0556	8.963e-70	240.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,1T530@1236|Gammaproteobacteria,1X2VM@135613|Chromatiales	135613|Chromatiales	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
EH2_k127_2713958_0	292415.Tbd_0802	5.792e-146	471.0	COG0530@1|root,COG0530@2|Bacteria,1PMXR@1224|Proteobacteria,2VNME@28216|Betaproteobacteria,1KSK4@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
EH2_k127_2713958_4	157072.XP_008868465.1	1.224e-07	58.0	COG0526@1|root,KOG0907@2759|Eukaryota	2759|Eukaryota	CO	cell redox homeostasis	-	GO:0003674,GO:0003824,GO:0004791,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006109,GO:0006950,GO:0006979,GO:0008047,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009636,GO:0009642,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019222,GO:0019725,GO:0019904,GO:0030234,GO:0031976,GO:0031984,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0080090,GO:0097237,GO:0098754,GO:0098772,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
EH2_k127_2713958_3	748280.NH8B_3859	2.079e-55	203.0	COG0454@1|root,COG3023@1|root,COG0456@2|Bacteria,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,2KR20@206351|Neisseriales	206351|Neisseriales	V	N-acetylmuramoyl-L-alanine amidase	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Acetyltransf_1,Amidase_2
EH2_k127_2732452_1	795666.MW7_0759	6.029e-92	308.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
EH2_k127_2732452_0	795666.MW7_0760	1.442e-138	453.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_2740739_2	1121116.KB894766_gene213	6.927e-42	160.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,4AA57@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
EH2_k127_2740739_3	582744.Msip34_0912	3.9e-11	66.0	COG1918@1|root,COG1918@2|Bacteria,1NA6D@1224|Proteobacteria,2VY9N@28216|Betaproteobacteria,2KN7T@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
EH2_k127_2740739_0	1122236.KB905141_gene1444	7.623e-223	707.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,2KKYE@206350|Nitrosomonadales	206350|Nitrosomonadales	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
EH2_k127_2740739_1	1123393.KB891329_gene1043	1.812e-146	482.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KS3Z@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HATPase_c,HisKA,Hpt,PAS_8,Response_reg
EH2_k127_2777220_2	292415.Tbd_0566	7.072e-11	65.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1KT0V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH2_k127_2777220_1	1123392.AQWL01000004_gene2731	5.455e-43	163.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,2WC80@28216|Betaproteobacteria,1KT7X@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
EH2_k127_2777220_0	62928.azo2920	6.772e-115	384.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
EH2_k127_2780987_1	261292.Nit79A3_2979	2.599e-82	282.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,373WD@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	cph2_3	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS_4
EH2_k127_2780987_2	1286093.C266_10836	6.104e-58	222.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,1K2D7@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HDOD,Pkinase
EH2_k127_2780987_0	1123392.AQWL01000010_gene2299	1.563e-152	490.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,1KS7Y@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
EH2_k127_2780987_3	1158760.AQXP01000052_gene1713	7.667e-18	87.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH2_k127_2780987_4	62928.azo2590	1.436e-05	49.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,2VN09@28216|Betaproteobacteria,2KW38@206389|Rhodocyclales	206389|Rhodocyclales	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
EH2_k127_2781764_4	395494.Galf_2198	1.542e-05	50.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2781764_3	522306.CAP2UW1_2544	3.418e-43	160.0	COG1917@1|root,COG1917@2|Bacteria,1MZNT@1224|Proteobacteria,2WGVF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
EH2_k127_2781764_1	292415.Tbd_0785	1.212e-113	376.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,1KRDB@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
EH2_k127_2781764_0	292415.Tbd_0786	7.03e-157	497.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1KRCJ@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
EH2_k127_2781764_2	1123392.AQWL01000004_gene2535	2.398e-84	283.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1KS6B@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH2_k127_2799198_3	697282.Mettu_1584	1.544e-35	147.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1XG89@135618|Methylococcales	135618|Methylococcales	P	PFAM Regulator of K conductance, N-terminal	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,TrkA_N
EH2_k127_2799198_2	159087.Daro_3348	5.443e-45	169.0	2D2K4@1|root,32TD0@2|Bacteria,1MZKF@1224|Proteobacteria,2VUUX@28216|Betaproteobacteria,2KZ3H@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
EH2_k127_2799198_1	1163617.SCD_n01865	7.609e-99	335.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
EH2_k127_2799198_0	443143.GM18_0084	1.163e-235	743.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
EH2_k127_2827558_0	1123393.KB891327_gene379	6.255e-134	428.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,1KREK@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
EH2_k127_2827558_5	882378.RBRH_02526	1.956e-87	292.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
EH2_k127_2827558_4	1112274.KI911560_gene1989	1.216e-97	319.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,2KKS7@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
EH2_k127_2827558_6	1131553.JIBI01000007_gene1197	1.535e-64	222.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,3737D@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
EH2_k127_2827558_7	1123392.AQWL01000003_gene397	3.881e-32	128.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,1KRV7@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
EH2_k127_2827558_2	292415.Tbd_1140	5.116e-115	375.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KRM4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
EH2_k127_2827558_1	1304883.KI912532_gene1528	1.094e-131	424.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,2KUX6@206389|Rhodocyclales	206389|Rhodocyclales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
EH2_k127_2827558_3	1304883.KI912532_gene1529	1.344e-110	383.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VN6W@28216|Betaproteobacteria,2KVGJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
EH2_k127_2845360_3	292415.Tbd_0239	5.469e-80	272.0	2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2WIIE@28216|Betaproteobacteria,1KRXD@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
EH2_k127_2845360_5	546266.NEIMUCOT_06352	7.394e-10	63.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	yqiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
EH2_k127_2845360_2	1158165.KB898871_gene2220	6.073e-83	287.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_2845360_1	395494.Galf_0288	8.16e-94	321.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,44V8D@713636|Nitrosomonadales	28216|Betaproteobacteria	HL	Thiamine monophosphate synthase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
EH2_k127_2845360_4	292415.Tbd_0026	4.804e-22	100.0	2BWYA@1|root,32WXT@2|Bacteria,1N26T@1224|Proteobacteria,2VXGX@28216|Betaproteobacteria,1KT5N@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2845360_0	1123393.KB891332_gene2752	1.361e-100	332.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,1KRQG@119069|Hydrogenophilales	119069|Hydrogenophilales	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
EH2_k127_2861205_6	580332.Slit_2977	3.113e-08	55.0	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria,44VBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH2_k127_2861205_1	1123392.AQWL01000002_gene1821	2.185e-196	621.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,1KSI1@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
EH2_k127_2861205_0	292415.Tbd_2727	3.178e-252	796.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
EH2_k127_2861205_4	85643.Tmz1t_3728	1.457e-23	102.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
EH2_k127_2861205_3	292415.Tbd_2726	7.551e-32	128.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1KTBP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
EH2_k127_2861205_2	1123393.KB891316_gene2123	1.738e-162	519.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2W9BF@28216|Betaproteobacteria,1KT6Y@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
EH2_k127_2861205_5	1123393.KB891316_gene2122	3.914e-16	79.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KT21@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
EH2_k127_2872309_1	1163617.SCD_n00905	5.329e-05	50.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_2872309_0	395494.Galf_2780	3.472e-95	340.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,44WBX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
EH2_k127_2889695_2	670307.HYPDE_38268	1.286e-30	134.0	COG2207@1|root,COG2207@2|Bacteria,1P3X1@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
EH2_k127_2889695_0	1232410.KI421426_gene1474	1.564e-159	519.0	COG3264@1|root,COG3264@2|Bacteria,1QUDC@1224|Proteobacteria,43DHA@68525|delta/epsilon subdivisions,2X8P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
EH2_k127_2889695_3	381666.H16_A2157	4.33e-23	107.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K7R1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
EH2_k127_2889695_1	1458357.BG58_28310	1.257e-102	342.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2VKSZ@28216|Betaproteobacteria,1K5PF@119060|Burkholderiaceae	28216|Betaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
EH2_k127_2895551_6	713586.KB900536_gene1803	5.684e-05	46.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
EH2_k127_2895551_0	292415.Tbd_2044	2.255e-289	915.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KRHF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Putative metal-binding domain of cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
EH2_k127_2895551_4	580332.Slit_0042	8.263e-91	309.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,44V3F@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
EH2_k127_2895551_2	1207076.ALAT01000230_gene674	2.715e-123	405.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1Z0PY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
EH2_k127_2895551_3	582744.Msip34_0971	8.295e-95	316.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,2KMJ9@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
EH2_k127_2895551_1	1123392.AQWL01000011_gene2256	4.708e-211	661.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,1KRWZ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
EH2_k127_2906155_4	1266925.JHVX01000011_gene1512	2.726e-19	87.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VR6N@28216|Betaproteobacteria,373PT@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
EH2_k127_2906155_3	1366050.N234_14350	6.391e-42	160.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,2WFVC@28216|Betaproteobacteria,1KI6J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
EH2_k127_2906155_2	261292.Nit79A3_3087	6.187e-53	203.0	COG5544@1|root,COG5544@2|Bacteria,1QU58@1224|Proteobacteria,2VQZ5@28216|Betaproteobacteria,3720M@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2906155_1	582744.Msip34_0855	1.924e-73	254.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,2KM3S@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
EH2_k127_2906155_0	1244869.H261_08518	8.84e-138	458.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2TSPP@28211|Alphaproteobacteria,2JQQJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
EH2_k127_2906155_5	360910.BAV3076	4.989e-13	82.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,3T48H@506|Alcaligenaceae	28216|Betaproteobacteria	S	SCP-2 sterol transfer family	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
EH2_k127_2906155_6	1123392.AQWL01000002_gene1965	3.176e-05	53.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,1KRE6@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
EH2_k127_2922460_0	1163617.SCD_n01915	0.0	1354.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
EH2_k127_2922460_6	580332.Slit_1972	7.377e-15	89.0	2EQBS@1|root,30WRI@2|Bacteria,1PWXX@1224|Proteobacteria,2WCFU@28216|Betaproteobacteria,44W00@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
EH2_k127_2922460_5	640081.Dsui_3432	4.045e-85	298.0	COG1538@1|root,COG1538@2|Bacteria,1R9PU@1224|Proteobacteria,2VPEH@28216|Betaproteobacteria,2KW3Y@206389|Rhodocyclales	206389|Rhodocyclales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_2922460_3	1123393.KB891316_gene1857	3.733e-100	339.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,1KSK7@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
EH2_k127_2922460_4	292415.Tbd_2464	3.695e-94	334.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KSM0@119069|Hydrogenophilales	119069|Hydrogenophilales	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH2_k127_2922460_1	1123393.KB891316_gene1827	1.518e-161	519.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KS03@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
EH2_k127_2922460_2	1163617.SCD_n01904	1.379e-122	399.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
EH2_k127_2951514_2	1120999.JONM01000002_gene566	1.977e-41	158.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales	206351|Neisseriales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
EH2_k127_2951514_0	1163617.SCD_n02664	1.891e-65	231.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria	28216|Betaproteobacteria	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
EH2_k127_2951514_1	1485544.JQKP01000002_gene1550	1.013e-57	205.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,44VN1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_2952796_0	1123393.KB891316_gene1212	2.882e-144	465.0	28I2K@1|root,2ZAEK@2|Bacteria,1R9HK@1224|Proteobacteria,2VZM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_2952796_2	572477.Alvin_0732	9.155e-40	151.0	COG2920@1|root,COG2920@2|Bacteria,1N6BU@1224|Proteobacteria,1S6FJ@1236|Gammaproteobacteria,1WYPC@135613|Chromatiales	135613|Chromatiales	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_2952796_1	1232683.ADIMK_2513	1.285e-49	179.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,1SANY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
EH2_k127_296764_1	1163617.SCD_n02922	1.499e-144	497.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
EH2_k127_296764_0	292415.Tbd_2549	1.228e-163	539.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,1KSV7@119069|Hydrogenophilales	119069|Hydrogenophilales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
EH2_k127_296764_6	1304883.KI912532_gene1113	1.605e-31	130.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
EH2_k127_296764_5	640081.Dsui_0659	1.908e-52	187.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_296764_3	1163617.SCD_n02926	9.473e-63	219.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
EH2_k127_296764_7	381666.H16_A0735	3.812e-28	115.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KA31@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
EH2_k127_296764_2	395494.Galf_0151	8.958e-118	386.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
EH2_k127_296764_4	1120999.JONM01000004_gene3677	3.266e-56	203.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,2KR43@206351|Neisseriales	206351|Neisseriales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
EH2_k127_2971554_0	1123393.KB891316_gene1117	2.043e-139	450.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1KRAS@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Trypsin	-	-	-	ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
EH2_k127_2971554_1	395494.Galf_2288	1.927e-131	428.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,HD_5,Response_reg
EH2_k127_2971554_2	640081.Dsui_2885	1.237e-15	81.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
EH2_k127_3005315_1	314345.SPV1_13262	1.487e-71	253.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
EH2_k127_3005315_2	1123392.AQWL01000001_gene1588	1.08e-70	243.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
EH2_k127_3005315_4	1123393.KB891316_gene1128	5.856e-45	167.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,1KS4V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_3005315_0	1163617.SCD_n00905	3.294e-90	308.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
EH2_k127_3005315_3	1163617.SCD_n00906	1.085e-46	181.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
EH2_k127_3009044_2	257310.BB3180	1.053e-30	122.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,3T1CD@506|Alcaligenaceae	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
EH2_k127_3009044_1	1123392.AQWL01000008_gene1156	5.102e-225	704.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria,1KSSF@119069|Hydrogenophilales	119069|Hydrogenophilales	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
EH2_k127_3009044_0	1123393.KB891317_gene2469	4.044e-290	899.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria,1KSGV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,FlpD,Pyr_redox_2
EH2_k127_3032992_3	697282.Mettu_3163	1.423e-43	168.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1NMCM@1224|Proteobacteria,1SPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
EH2_k127_3032992_1	1158762.KB898039_gene1708	1.498e-166	541.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Hpt,Response_reg
EH2_k127_3032992_2	1158762.KB898039_gene1707	4.376e-58	203.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1WYTZ@135613|Chromatiales	135613|Chromatiales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
EH2_k127_3032992_0	765910.MARPU_10245	2.3e-278	888.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria,1X2S5@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_9
EH2_k127_3040984_2	305700.B447_03468	1.068e-61	215.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,2VNKT@28216|Betaproteobacteria,2KVPF@206389|Rhodocyclales	206389|Rhodocyclales	H	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_25
EH2_k127_3040984_0	261292.Nit79A3_2344	6.895e-121	406.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2VHZ6@28216|Betaproteobacteria,371TT@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase, class I	-	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_3040984_1	1163617.SCD_n00989	4.437e-114	372.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	abc transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH2_k127_3042516_2	292415.Tbd_2404	2.609e-09	59.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,1KS10@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
EH2_k127_3042516_1	1123393.KB891327_gene271	6.148e-24	103.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1KRWM@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
EH2_k127_3042516_0	1123393.KB891327_gene270	4.906e-144	465.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,1KSEN@119069|Hydrogenophilales	119069|Hydrogenophilales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
EH2_k127_3070396_1	1415630.U771_22565	4.963e-177	559.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
EH2_k127_3070396_0	292415.Tbd_1423	2.715e-206	651.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
EH2_k127_3070396_2	1123393.KB891316_gene1304	7.729e-44	163.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria,1KSTX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
EH2_k127_3070396_3	1121382.JQKG01000015_gene1660	2.914e-12	74.0	2DP69@1|root,330Q1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3072493_2	742159.HMPREF0004_0368	4.959e-13	69.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,3T2A2@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_3072493_1	640081.Dsui_3338	7.088e-59	208.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
EH2_k127_3072493_0	279714.FuraDRAFT_3140	8.223e-153	494.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,2KPM8@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
EH2_k127_3072493_3	261292.Nit79A3_1727	3.847e-09	60.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF_2,HD
EH2_k127_3098547_9	388051.AUFE01000030_gene5108	9.574e-57	216.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,1JZWI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
EH2_k127_3098547_6	1485544.JQKP01000013_gene1819	2.388e-108	360.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,44VGR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
EH2_k127_3098547_8	519989.ECTPHS_03227	5.467e-68	240.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
EH2_k127_3098547_2	62928.azo1627	9.709e-233	723.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,2KUW2@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
EH2_k127_3098547_11	1236959.BAMT01000001_gene1638	6.722e-34	131.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KN5P@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
EH2_k127_3098547_7	1123393.KB891333_gene2577	1.044e-107	353.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KS53@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH2_k127_3098547_5	292415.Tbd_1550	1.317e-128	417.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1KRCS@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
EH2_k127_3098547_10	1123368.AUIS01000014_gene2319	4.376e-52	203.0	COG1807@1|root,COG1807@2|Bacteria,1RE4T@1224|Proteobacteria,1S5IF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
EH2_k127_3098547_3	1123393.KB891333_gene2579	5.979e-149	479.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KRA1@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
EH2_k127_3098547_4	583345.Mmol_1146	3.966e-143	461.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,2KMA0@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
EH2_k127_3098547_12	94624.Bpet1751	6.045e-29	115.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,3T4QE@506|Alcaligenaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
EH2_k127_3098547_13	1266925.JHVX01000004_gene1112	1.076e-22	103.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,373C3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
EH2_k127_3098547_1	1163617.SCD_n01539	1.084e-265	824.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH2_k127_3098547_0	1236959.BAMT01000001_gene1630	8.451e-287	889.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales	206350|Nitrosomonadales	CI	TIGRFAM oxaloacetate decarboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
EH2_k127_310189_4	1121035.AUCH01000006_gene629	1.012e-06	54.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,2KWVJ@206389|Rhodocyclales	206389|Rhodocyclales	D	cell division protein	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH2_k127_310189_1	1121035.AUCH01000006_gene630	9.017e-246	771.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
EH2_k127_310189_3	768671.ThimaDRAFT_0135	1.009e-20	98.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1X0VZ@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
EH2_k127_310189_0	292415.Tbd_0091	3.007e-301	929.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,1KRGZ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
EH2_k127_310189_2	292415.Tbd_0092	2.069e-48	175.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1KRSD@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
EH2_k127_3112126_6	864073.HFRIS_015631	1.023e-08	56.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,47796@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
EH2_k127_3112126_2	580332.Slit_0302	4.901e-81	271.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,44WN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
EH2_k127_3112126_0	580332.Slit_0303	8.578e-264	815.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
EH2_k127_3112126_3	1049564.TevJSym_bd00250	9.168e-77	265.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
EH2_k127_3112126_4	1163617.SCD_n02110	4.33e-36	150.0	2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2VTMU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CNP1-like family	-	-	-	-	-	-	-	-	-	-	-	-	CNP1
EH2_k127_3112126_1	582744.Msip34_0154	2.578e-113	387.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,2KKSU@206350|Nitrosomonadales	206350|Nitrosomonadales	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
EH2_k127_3112126_5	925775.XVE_0788	1.112e-32	132.0	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,1S71T@1236|Gammaproteobacteria,1X7C4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3112160_5	292415.Tbd_1516	6.247e-30	119.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
EH2_k127_3112160_2	519989.ECTPHS_01294	1.46e-62	238.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,1X13E@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH2_k127_3112160_3	1131553.JIBI01000006_gene1101	5.438e-62	224.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,371QS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Cytochrome c assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
EH2_k127_3112160_0	279714.FuraDRAFT_0450	4.756e-204	643.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,2KPW4@206351|Neisseriales	206351|Neisseriales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
EH2_k127_3112160_4	292415.Tbd_2374	7.157e-50	184.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,1KRS5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RimM N-terminal domain	-	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
EH2_k127_3112160_1	85643.Tmz1t_2783	1.176e-85	288.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KUD3@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
EH2_k127_3116683_0	265072.Mfla_2074	1.378e-299	927.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KKET@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH2_k127_3116683_1	1165096.ARWF01000001_gene740	5.529e-33	132.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,2KKM4@206350|Nitrosomonadales	206350|Nitrosomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
EH2_k127_3132857_3	1485544.JQKP01000002_gene1540	1.778e-34	136.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,44VI0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
EH2_k127_3132857_0	1163617.SCD_n02918	4.117e-119	397.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
EH2_k127_3132857_2	1158146.KB907126_gene1490	1.136e-39	149.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_3132857_1	1123393.KB891316_gene2085	1.515e-84	288.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,1KRWY@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Ribosomal RNA adenine dimethylase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_3132857_4	1123392.AQWL01000006_gene575	4.846e-10	59.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1KRCT@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
EH2_k127_3150859_1	580332.Slit_1695	5.039e-125	409.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_3150859_2	1042375.AFPL01000056_gene2383	3.179e-97	325.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
EH2_k127_3150859_3	85643.Tmz1t_0779	1.077e-93	312.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,2KUF1@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
EH2_k127_3150859_4	1123393.KB891316_gene1513	7.155e-48	181.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,1KS8A@119069|Hydrogenophilales	119069|Hydrogenophilales	D	TolA binding protein trimerisation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TolA_bind_tri
EH2_k127_3150859_5	1218074.BAXZ01000005_gene1344	6.579e-42	164.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,1K2YN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
EH2_k127_3150859_0	1123393.KB891316_gene1515	9.346e-146	474.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KRY5@119069|Hydrogenophilales	119069|Hydrogenophilales	U	TolB amino-terminal domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
EH2_k127_3150859_6	1163617.SCD_n00675	8.602e-19	93.0	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell division and transport-associated protein TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
EH2_k127_3163830_2	323261.Noc_1975	5.085e-14	72.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH2_k127_3163830_0	292415.Tbd_0286	1.972e-160	512.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
EH2_k127_3163830_1	1123393.KB891330_gene811	9.919e-125	412.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,1KSKR@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
EH2_k127_3173651_4	1123393.KB891327_gene383	1.028e-73	249.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,1KRDN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
EH2_k127_3173651_3	1163617.SCD_n00947	4.575e-89	296.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
EH2_k127_3173651_5	1123393.KB891327_gene385	2.664e-72	256.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
EH2_k127_3173651_7	583345.Mmol_1596	1.768e-45	166.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,2KMXI@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
EH2_k127_3173651_0	1163617.SCD_n00950	0.0	1006.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
EH2_k127_3173651_1	640081.Dsui_3038	3.892e-253	787.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
EH2_k127_3173651_2	1163617.SCD_n00952	5.041e-185	590.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
EH2_k127_3173651_6	402777.KB235904_gene4108	1.799e-71	260.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
EH2_k127_3192887_2	1163617.SCD_n02789	1.452e-58	214.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
EH2_k127_3192887_4	748247.AZKH_0444	3.233e-33	132.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
EH2_k127_3192887_6	1163617.SCD_n02791	6.332e-08	60.0	COG3030@1|root,COG3030@2|Bacteria,1NHHU@1224|Proteobacteria,2VX8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
EH2_k127_3192887_0	1123393.KB891330_gene846	7.489e-129	427.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1KS61@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
EH2_k127_3192887_1	1121035.AUCH01000008_gene1107	5.217e-86	295.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,2KUYU@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
EH2_k127_3192887_5	1163617.SCD_n00093	3.871e-24	108.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH2_k127_3192887_3	1123393.KB891330_gene843	2.24e-44	162.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KRG5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
EH2_k127_3205108_2	1163617.SCD_n00389	1.59e-83	287.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
EH2_k127_3205108_0	1123392.AQWL01000003_gene452	0.0	1045.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,1KSD8@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Polyphosphate kinase middle domain	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
EH2_k127_3205108_1	153948.NAL212_2861	9.95e-125	416.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,372SC@32003|Nitrosomonadales	28216|Betaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
EH2_k127_3205108_3	265072.Mfla_1912	2.577e-33	132.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,2KMQR@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
EH2_k127_3222374_1	1163617.SCD_n01585	1.715e-47	176.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,2VZ32@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH2_k127_3222374_0	381666.H16_A1621	6.27e-158	510.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,1KBX2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
EH2_k127_3227371_0	1304883.KI912532_gene386	4.854e-113	388.0	COG4389@1|root,COG4389@2|Bacteria,1MWEH@1224|Proteobacteria,2VIZV@28216|Betaproteobacteria,2KUTK@206389|Rhodocyclales	206389|Rhodocyclales	L	Site-specific recombinase	-	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
EH2_k127_3229864_2	1123393.KB891326_gene139	3.293e-130	422.0	COG1527@1|root,COG1527@2|Bacteria,1R7PV@1224|Proteobacteria,2W2GY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
EH2_k127_3229864_1	1123393.KB891326_gene140	4.303e-275	858.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,2W04K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
EH2_k127_3229864_4	1123393.KB891326_gene141	9.115e-54	192.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,2W4JN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
EH2_k127_3229864_5	1123393.KB891326_gene142	4.833e-46	168.0	COG1436@1|root,COG1436@2|Bacteria,1MZUE@1224|Proteobacteria,2W5EY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (F/14-kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_F
EH2_k127_3229864_3	1123393.KB891326_gene143	1.03e-80	274.0	COG1390@1|root,COG1390@2|Bacteria,1R8BT@1224|Proteobacteria,2W49R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type proton ATPase subunit E	-	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
EH2_k127_3229864_0	1123393.KB891326_gene144	0.0	1063.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
EH2_k127_3229864_6	1123393.KB891326_gene145	1.952e-25	106.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
EH2_k127_323306_1	443143.GM18_4009	3.987e-21	109.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42R7Z@68525|delta/epsilon subdivisions,2WN0B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
EH2_k127_323306_0	1123393.KB891326_gene84	5.571e-83	299.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KREN@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,dCache_1
EH2_k127_3239798_0	1163617.SCD_n00823	3.157e-283	875.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
EH2_k127_3239798_6	686340.Metal_0082	6.862e-22	108.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria,1XFCG@135618|Methylococcales	135618|Methylococcales	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_3239798_7	1116472.MGMO_43c00280	6.354e-17	93.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria,1XFCG@135618|Methylococcales	135618|Methylococcales	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_3239798_4	314345.SPV1_01487	4.72e-55	202.0	293CN@1|root,2ZQV6@2|Bacteria,1RDZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3239798_5	397945.Aave_1453	1.597e-37	149.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,4AECU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
EH2_k127_3239798_2	75379.Tint_2978	3.31e-85	289.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2VS07@28216|Betaproteobacteria,1KMUT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Protein of unknown function (DUF2470)	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
EH2_k127_3239798_3	243365.CV_0809	1.257e-81	276.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJMC@28216|Betaproteobacteria,2KPNQ@206351|Neisseriales	206351|Neisseriales	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
EH2_k127_3239798_1	265072.Mfla_1889	8.183e-150	489.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KKYP@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
EH2_k127_3250326_2	596154.Alide2_1763	4.021e-49	175.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,4ADCX@80864|Comamonadaceae	28216|Betaproteobacteria	P	Superoxide dismutase	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Sod_Fe_C
EH2_k127_3250326_3	1163617.SCD_n02014	2.71e-29	124.0	COG0607@1|root,COG0607@2|Bacteria,1NBYS@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_3250326_1	640081.Dsui_1139	7.888e-78	267.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,2KYFQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
EH2_k127_3250326_0	596154.Alide2_1768	7.545e-170	546.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
EH2_k127_3250326_5	1123368.AUIS01000001_gene1908	8.223e-11	66.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3250326_4	1150469.RSPPHO_01671	3.57e-17	82.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,2JQ9F@204441|Rhodospirillales	204441|Rhodospirillales	I	Lysophospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
EH2_k127_3315727_5	748247.AZKH_0753	3.737e-28	114.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
EH2_k127_3315727_4	1366050.N234_19190	6.359e-30	121.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,1K9F0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
EH2_k127_3315727_1	1236959.BAMT01000006_gene433	1.319e-107	355.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,2KKDW@206350|Nitrosomonadales	206350|Nitrosomonadales	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
EH2_k127_3315727_0	640081.Dsui_1404	1.47e-120	394.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,2KVD2@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_3315727_6	1236959.BAMT01000006_gene431	5.221e-05	53.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2W81J@28216|Betaproteobacteria,2KNBR@206350|Nitrosomonadales	206350|Nitrosomonadales	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
EH2_k127_3315727_2	1266925.JHVX01000011_gene1527	1.178e-59	213.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,3731H@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
EH2_k127_3315727_3	1217718.ALOU01000072_gene5031	1.629e-54	194.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH2_k127_3339916_3	765913.ThidrDRAFT_2313	1.257e-46	169.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,Response_reg,SBP_bac_3
EH2_k127_3339916_4	87626.PTD2_04958	0.0005692	43.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3339916_0	640081.Dsui_1124	1.291e-135	436.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,2KUBV@206389|Rhodocyclales	206389|Rhodocyclales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
EH2_k127_3339916_2	1123393.KB891316_gene1450	4.233e-63	228.0	COG3221@1|root,COG3221@2|Bacteria,1PUJG@1224|Proteobacteria,2VKHU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_3339916_1	1049564.TevJSym_ax00320	7.066e-109	387.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
EH2_k127_3345294_1	1158762.KB898058_gene132	4.207e-51	186.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
EH2_k127_3345294_2	292415.Tbd_1533	3.548e-24	104.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KTA7@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
EH2_k127_3345294_3	1002804.HBZC1_04310	5.946e-22	101.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
EH2_k127_3345294_0	713587.THITH_07505	6.055e-96	317.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,1RQ1I@1236|Gammaproteobacteria,1X08E@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
EH2_k127_3351499_0	522306.CAP2UW1_0968	1.526e-121	405.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
EH2_k127_3351499_1	522306.CAP2UW1_0967	1.315e-81	276.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2VV7N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
EH2_k127_3351499_2	472759.Nhal_0641	8.789e-71	253.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X2A0@135613|Chromatiales	135613|Chromatiales	M	Thrombospondin type 3 repeat	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
EH2_k127_3351499_3	153948.NAL212_1480	3.071e-52	188.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,373EC@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
EH2_k127_3363915_3	1163617.SCD_n00077	5.903e-16	78.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_3363915_2	1123368.AUIS01000005_gene398	1.568e-28	126.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,2NE49@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
EH2_k127_3363915_0	1163617.SCD_n00082	1.776e-126	415.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
EH2_k127_3363915_1	1121352.JHZP01000001_gene952	1.61e-120	396.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,2KPUN@206351|Neisseriales	206351|Neisseriales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
EH2_k127_3363915_4	159087.Daro_0011	1.842e-08	56.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,2KUNH@206389|Rhodocyclales	206389|Rhodocyclales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
EH2_k127_3375073_4	45351.EDO29371	2.291e-77	267.0	COG5001@1|root,2S700@2759|Eukaryota,3AD5N@33154|Opisthokonta,3C24C@33208|Metazoa	33208|Metazoa	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_3375073_5	1123393.KB891316_gene1419	4.4e-67	242.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VT0X@28216|Betaproteobacteria,1KSZ1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
EH2_k127_3375073_3	1485544.JQKP01000003_gene125	4.498e-85	284.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,44VS0@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
EH2_k127_3375073_6	1163617.SCD_n02112	2.936e-56	203.0	COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,2WGXX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_3375073_7	292415.Tbd_2109	8.874e-19	94.0	2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,2W41I@28216|Betaproteobacteria,1KTCV@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3375073_1	1123393.KB891316_gene1415	2.472e-185	584.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KS7N@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
EH2_k127_3375073_2	1123392.AQWL01000001_gene1372	1.161e-114	371.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1KRBR@119069|Hydrogenophilales	119069|Hydrogenophilales	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
EH2_k127_3375073_0	1123487.KB892844_gene837	5.478e-212	661.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,2KV3G@206389|Rhodocyclales	206389|Rhodocyclales	E	COG1982 Arginine lysine ornithine decarboxylases	adiA	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
EH2_k127_3376620_2	1454004.AW11_02278	3.937e-87	304.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
EH2_k127_3376620_0	1283300.ATXB01000001_gene1723	9.934e-153	495.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,1S0NV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
EH2_k127_3376620_1	1165096.ARWF01000001_gene2241	4.83e-149	480.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KKV0@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_3376620_3	207954.MED92_01861	2.325e-44	163.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XII3@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
EH2_k127_3393348_6	870187.Thini_1237	3.585e-55	202.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,45ZTP@72273|Thiotrichales	72273|Thiotrichales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
EH2_k127_3393348_1	1255043.TVNIR_0259	4.248e-216	686.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
EH2_k127_3393348_5	580332.Slit_1798	2.161e-59	214.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,44V0F@713636|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
EH2_k127_3393348_3	762966.HMPREF9439_00189	1.078e-65	231.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,4PQD6@995019|Sutterellaceae	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
EH2_k127_3393348_2	1163617.SCD_n02738	3.947e-117	380.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
EH2_k127_3393348_7	261292.Nit79A3_1270	6.137e-10	61.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY1Y@28216|Betaproteobacteria,373N5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
EH2_k127_3393348_4	1288494.EBAPG3_12780	1.042e-61	218.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
EH2_k127_3393348_0	713587.THITH_16200	9.1e-258	803.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1WWM9@135613|Chromatiales	135613|Chromatiales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
EH2_k127_3393901_0	1123393.KB891328_gene528	2.948e-112	369.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,1KRPC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_3393901_1	765910.MARPU_02400	1.339e-72	254.0	COG0697@1|root,COG0697@2|Bacteria,1RJFE@1224|Proteobacteria,1RZF0@1236|Gammaproteobacteria,1WWYW@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_3393901_4	1163617.SCD_n02497	2.198e-22	104.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,DUF302
EH2_k127_3393901_2	1502770.JQMG01000001_gene162	3.514e-57	200.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KMZX@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
EH2_k127_3393901_3	1163617.SCD_n01847	1.218e-36	140.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
EH2_k127_3399073_2	589865.DaAHT2_2510	1.645e-183	582.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42MRE@68525|delta/epsilon subdivisions,2WIP0@28221|Deltaproteobacteria,2MIDJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
EH2_k127_3399073_4	589865.DaAHT2_2511	1.26e-60	232.0	2C5J8@1|root,30F9Z@2|Bacteria,1RE16@1224|Proteobacteria,42RYB@68525|delta/epsilon subdivisions,2WNIF@28221|Deltaproteobacteria,2MJSR@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3399073_0	589865.DaAHT2_2512	8.25e-266	844.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MIEG@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
EH2_k127_3399073_6	589865.DaAHT2_2513	1.864e-31	127.0	COG0745@1|root,COG0745@2|Bacteria	589865.DaAHT2_2513|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3399073_1	580332.Slit_0865	3.943e-197	621.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,2VM57@28216|Betaproteobacteria	28216|Betaproteobacteria	P	NhaP-type Na H and K H antiporters with a unique C-terminal domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	CorC_HlyC,Na_H_Exchanger,TrkA_C
EH2_k127_3399073_7	1163617.SCD_n02018	2.84e-11	66.0	COG1055@1|root,COG1055@2|Bacteria,1PUZK@1224|Proteobacteria,2VKEF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3399073_5	697282.Mettu_1583	1.203e-53	199.0	COG1226@1|root,COG1226@2|Bacteria,1QRWR@1224|Proteobacteria,1SPPS@1236|Gammaproteobacteria,1XG34@135618|Methylococcales	135618|Methylococcales	C	PFAM Regulator of K conductance, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_N
EH2_k127_3399073_3	1049564.TevJSym_aa01740	2.14e-95	323.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,Na_H_Exchanger,TrkA_C,TrkA_N
EH2_k127_3410613_0	748247.AZKH_1542	1.101e-89	302.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,2KXSX@206389|Rhodocyclales	206389|Rhodocyclales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
EH2_k127_3410613_1	296591.Bpro_2589	1.497e-83	283.0	COG2890@1|root,COG2890@2|Bacteria,1QYJ3@1224|Proteobacteria,2WHFP@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
EH2_k127_3413392_2	1163617.SCD_n01481	7.198e-19	93.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
EH2_k127_3413392_1	1123392.AQWL01000003_gene195	1.289e-90	306.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,1KSYT@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
EH2_k127_3413392_0	1163617.SCD_n01875	0.0	1212.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
EH2_k127_3414040_5	292415.Tbd_2533	1.852e-49	194.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,1KRSQ@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
EH2_k127_3414040_0	1123393.KB891330_gene854	1.466e-163	522.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2VURW@28216|Betaproteobacteria,1KSAA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Homoserine O-succinyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTS
EH2_k127_3414040_2	1123393.KB891330_gene855	3.081e-154	499.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,2WBNB@28216|Betaproteobacteria,1KS8Q@119069|Hydrogenophilales	119069|Hydrogenophilales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3414040_3	1123392.AQWL01000006_gene721	3.336e-134	436.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cobalamin synthesis protein	yjiA_2	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
EH2_k127_3414040_7	1121035.AUCH01000006_gene684	1.925e-32	132.0	COG0840@1|root,COG0840@2|Bacteria,1PGTY@1224|Proteobacteria,2WB5T@28216|Betaproteobacteria,2KZDD@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
EH2_k127_3414040_1	1123392.AQWL01000002_gene2034	1.341e-161	513.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KRBV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
EH2_k127_3414040_8	1123392.AQWL01000001_gene1363	7.439e-27	123.0	COG0845@1|root,COG0845@2|Bacteria,1R9JJ@1224|Proteobacteria,2W4AP@28216|Betaproteobacteria,1KT2Q@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
EH2_k127_3414040_4	1123393.KB891316_gene1424	1.371e-88	308.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,2W1FP@28216|Betaproteobacteria,1KS5E@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_3414040_6	1123392.AQWL01000001_gene1361	1.75e-32	128.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria,1KS9C@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_3427003_2	666681.M301_2010	5.906e-37	140.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KKPF@206350|Nitrosomonadales	206350|Nitrosomonadales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
EH2_k127_3427003_1	682795.AciX8_1751	4.907e-146	479.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,3Y303@57723|Acidobacteria,2JINA@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
EH2_k127_3427003_0	62928.azo3579	0.0	1099.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,2KUSP@206389|Rhodocyclales	206389|Rhodocyclales	H	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
EH2_k127_3430090_2	153948.NAL212_2964	7.651e-31	138.0	28PH1@1|root,2ZC7N@2|Bacteria,1RAFS@1224|Proteobacteria,2WBZ8@28216|Betaproteobacteria,37423@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3430090_0	338969.Rfer_1747	2.126e-81	279.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VS5T@28216|Betaproteobacteria,4AJE7@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3430090_3	565045.NOR51B_2370	4.062e-16	82.0	COG2863@1|root,COG2863@2|Bacteria,1N7NU@1224|Proteobacteria,1SH3Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3430090_1	1149133.ppKF707_4672	1.358e-39	155.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
EH2_k127_3441035_2	398767.Glov_0813	1.544e-58	216.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria	1224|Proteobacteria	S	peptidase m48, ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_3441035_3	1123368.AUIS01000016_gene2541	2.206e-58	210.0	COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,1S328@1236|Gammaproteobacteria,2NCGK@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
EH2_k127_3441035_4	1123392.AQWL01000006_gene543	2.77e-22	101.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2WCAE@28216|Betaproteobacteria,1KTBI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
EH2_k127_3441035_1	62928.azo2824	7.537e-87	295.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2VIX0@28216|Betaproteobacteria,2KVCD@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
EH2_k127_3441035_0	1123392.AQWL01000009_gene1107	3.609e-178	567.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1KRFZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
EH2_k127_3444867_1	62928.azo3973	4.452e-90	302.0	COG3179@1|root,COG3409@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	exeA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	-	ko:K02450,ko:K03791,ko:K17733	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko01011,ko02044	9.B.42	GH19	-	AAA_22,Glyco_hydro_19,PG_binding_1
EH2_k127_3444867_0	935863.AWZR01000001_gene1664	3.818e-148	506.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X52B@135614|Xanthomonadales	135614|Xanthomonadales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
EH2_k127_3482719_0	1163617.SCD_n01151	2.006e-226	713.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
EH2_k127_3482719_1	1123393.KB891333_gene2645	3.189e-35	134.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,2WFUM@28216|Betaproteobacteria,1KTIG@119069|Hydrogenophilales	119069|Hydrogenophilales	O	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
EH2_k127_3498264_2	1123392.AQWL01000001_gene1511	8.687e-37	143.0	296I8@1|root,2ZTTR@2|Bacteria,1P5PJ@1224|Proteobacteria,2W67A@28216|Betaproteobacteria,1KT4U@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3498264_0	1121035.AUCH01000026_gene3371	5.365e-228	721.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,2KV1E@206389|Rhodocyclales	206389|Rhodocyclales	O	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
EH2_k127_3498264_1	1157490.EL26_06180	6.045e-76	262.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9
EH2_k127_3521538_10	1163617.SCD_n01675	4.495e-51	183.0	COG0346@1|root,COG0346@2|Bacteria,1PVYI@1224|Proteobacteria,2VVCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
EH2_k127_3521538_1	1123393.KB891326_gene237	2.216e-164	527.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria,1KSW2@119069|Hydrogenophilales	119069|Hydrogenophilales	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
EH2_k127_3521538_5	1163617.SCD_n02051	7.465e-103	352.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VRWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH2_k127_3521538_0	1123393.KB891329_gene948	0.0	1395.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF1631,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_4
EH2_k127_3521538_2	1123392.AQWL01000004_gene2826	2.247e-160	517.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,1KSBK@119069|Hydrogenophilales	119069|Hydrogenophilales	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
EH2_k127_3521538_4	1123392.AQWL01000004_gene2827	8.651e-119	386.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1KRSX@119069|Hydrogenophilales	119069|Hydrogenophilales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
EH2_k127_3521538_6	1123393.KB891330_gene860	1.792e-102	339.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria,1KST1@119069|Hydrogenophilales	119069|Hydrogenophilales	K	transmembrane transcriptional regulator (Anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3521538_7	292415.Tbd_1654	1.022e-70	242.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,1KT1T@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_3521538_11	1123393.KB891330_gene862	1.129e-50	185.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,2VU7D@28216|Betaproteobacteria,1KT5V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
EH2_k127_3521538_9	864051.BurJ1DRAFT_4367	4.346e-62	220.0	2DKVG@1|root,30GRY@2|Bacteria,1RDQT@1224|Proteobacteria,2VVQC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
EH2_k127_3521538_12	1122236.KB905141_gene1334	1.457e-41	172.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2VSKQ@28216|Betaproteobacteria,2KP39@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_3521538_8	395494.Galf_1699	1.592e-69	260.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,44VQN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
EH2_k127_3521538_3	292415.Tbd_1228	7.08e-156	509.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KS5V@119069|Hydrogenophilales	119069|Hydrogenophilales	L	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
EH2_k127_3550719_0	323259.Mhun_1141	4.14e-95	314.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,2N916@224756|Methanomicrobia	224756|Methanomicrobia	G	PEP-utilising enzyme, TIM barrel domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH2_k127_3550719_1	1121920.AUAU01000010_gene52	6.588e-39	153.0	2DC1J@1|root,32TYP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3550719_3	153948.NAL212_0856	2.99e-11	68.0	2AHBD@1|root,317MV@2|Bacteria,1PYZC@1224|Proteobacteria,2WE3F@28216|Betaproteobacteria,374B6@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3550719_2	1163617.SCD_n00484	4.55e-25	108.0	2DZHF@1|root,33JTD@2|Bacteria,1R3DF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3571222_2	292415.Tbd_2547	3.61e-78	268.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3571222_3	1123393.KB891316_gene2045	5.586e-70	239.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1KS9K@119069|Hydrogenophilales	119069|Hydrogenophilales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
EH2_k127_3571222_0	1123368.AUIS01000019_gene1232	1.324e-94	316.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,2NCXY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
EH2_k127_3571222_1	292415.Tbd_2669	1.566e-79	273.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,2W50B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
EH2_k127_3571222_4	1165096.ARWF01000001_gene2241	6.931e-11	63.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KKV0@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_3573124_1	765913.ThidrDRAFT_1424	6.074e-137	440.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria,1WXHU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3573124_7	765910.MARPU_01555	1.979e-23	105.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1WY72@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM clan AA aspartic protease, TIGR02281 family	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
EH2_k127_3573124_3	1123393.KB891327_gene481	1.399e-78	282.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria,1KSDS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
EH2_k127_3573124_2	1123392.AQWL01000003_gene184	5.387e-129	418.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KRF3@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
EH2_k127_3573124_0	640081.Dsui_2711	5.449e-167	533.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,2KUDN@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
EH2_k127_3573124_5	1123393.KB891327_gene490	5.835e-37	142.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria,1KT5S@119069|Hydrogenophilales	119069|Hydrogenophilales	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
EH2_k127_3573124_6	1123253.AUBD01000001_gene1715	1.98e-35	142.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1X5TH@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
EH2_k127_3573124_4	1123392.AQWL01000003_gene515	1.739e-76	259.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1KRPQ@119069|Hydrogenophilales	119069|Hydrogenophilales	I	YgbB family	-	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
EH2_k127_3573124_8	748247.AZKH_2760	2.919e-10	64.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,2KWXS@206389|Rhodocyclales	206389|Rhodocyclales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
EH2_k127_3574347_5	1286631.X805_29000	2.599e-92	323.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,2VPEA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
EH2_k127_3574347_6	292415.Tbd_1198	7.216e-21	100.0	2BZ72@1|root,32Z0T@2|Bacteria,1NBTY@1224|Proteobacteria,2VX7F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3574347_4	768671.ThimaDRAFT_3709	1.452e-115	379.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1X0AG@135613|Chromatiales	135613|Chromatiales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
EH2_k127_3574347_3	1123393.KB891316_gene1276	1.267e-140	453.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,1KRK5@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
EH2_k127_3574347_1	1232683.ADIMK_1477	2.223e-157	502.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
EH2_k127_3574347_0	1123393.KB891316_gene1087	2.254e-212	672.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1KRJ4@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
EH2_k127_3574347_2	1454004.AW11_01428	1.375e-148	475.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,1KQJJ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH2_k127_3615775_2	159087.Daro_0080	7.339e-46	171.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VMK8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
EH2_k127_3615775_1	1123393.KB891330_gene892	1.672e-171	544.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2VSIQ@28216|Betaproteobacteria,1KRWA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
EH2_k127_3615775_0	1123393.KB891316_gene2079	7.16e-303	946.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,1KRDE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH2_k127_3615775_3	1123392.AQWL01000006_gene581	1.173e-37	146.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,1KT91@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
EH2_k127_3618718_0	292415.Tbd_1230	2.679e-123	413.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
EH2_k127_3618718_1	622637.KE124774_gene2573	1.182e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,36XJI@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
EH2_k127_3636780_1	266264.Rmet_5623	5.461e-52	186.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,1K7VI@119060|Burkholderiaceae	28216|Betaproteobacteria	M	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
EH2_k127_3636780_0	1121035.AUCH01000002_gene1446	9.058e-148	471.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,2KUP1@206389|Rhodocyclales	206389|Rhodocyclales	O	Alkyl hydroperoxide reductase	-	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
EH2_k127_3639446_0	497965.Cyan7822_3387	5.895e-105	349.0	COG0549@1|root,COG0549@2|Bacteria,1GAQG@1117|Cyanobacteria,3KJ7G@43988|Cyanothece	1117|Cyanobacteria	E	Belongs to the carbamate kinase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH2_k127_3639446_1	1173024.KI912148_gene3523	5.117e-83	280.0	COG2403@1|root,COG2403@2|Bacteria,1G1FF@1117|Cyanobacteria	1117|Cyanobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
EH2_k127_3640504_4	1266925.JHVX01000007_gene2386	1.518e-64	232.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,372M5@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
EH2_k127_3640504_1	1163617.SCD_n02532	4.275e-103	340.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
EH2_k127_3640504_3	1000565.METUNv1_03154	4.252e-70	247.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VRK0@28216|Betaproteobacteria,2KWDG@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_3640504_2	522306.CAP2UW1_1706	2.001e-80	279.0	COG1639@1|root,COG1639@2|Bacteria,1PE3Q@1224|Proteobacteria,2WEH5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_3640504_0	557598.LHK_01605	8.394e-177	557.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KPRX@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
EH2_k127_365784_0	1123392.AQWL01000005_gene2880	1.129e-91	314.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	DUF1929,Laminin_G_3,Metallophos
EH2_k127_3718052_4	261292.Nit79A3_1740	0.0002298	44.0	2CUA5@1|root,32SUX@2|Bacteria,1RJP0@1224|Proteobacteria	1224|Proteobacteria	S	NADH ubiquinone oxidoreductase complex i intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
EH2_k127_3718052_3	198628.Dda3937_00496	3.13e-08	62.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,2JCCZ@204037|Dickeya	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	1.3.1.74,3.4.21.107	ko:K04771,ko:K04772,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
EH2_k127_3718052_2	1234364.AMSF01000016_gene1574	4.749e-20	97.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,1SAFA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
EH2_k127_3718052_0	1121035.AUCH01000002_gene1476	1.939e-31	130.0	2E80B@1|root,332EM@2|Bacteria,1N7PZ@1224|Proteobacteria,2VVZX@28216|Betaproteobacteria,2KXET@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3718052_1	768671.ThimaDRAFT_2301	1.548e-22	97.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S9TF@1236|Gammaproteobacteria,1X140@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
EH2_k127_3746563_0	1163617.SCD_n01950	4.286e-175	584.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
EH2_k127_3748067_1	582744.Msip34_1378	3.679e-38	144.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,2KKZF@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
EH2_k127_3748067_0	243365.CV_2475	3.034e-199	631.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,2KPE9@206351|Neisseriales	206351|Neisseriales	L	Psort location Cytoplasmic, score 8.96	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
EH2_k127_3752477_11	768671.ThimaDRAFT_1281	2.662e-12	68.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1WWXR@135613|Chromatiales	135613|Chromatiales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
EH2_k127_3752477_12	1120977.JHUX01000008_gene537	1.508e-05	51.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria,3NNM4@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
EH2_k127_3752477_2	292415.Tbd_0984	1.109e-85	295.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
EH2_k127_3752477_0	1123393.KB891329_gene1037	4.806e-218	698.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,1KS3W@119069|Hydrogenophilales	119069|Hydrogenophilales	T	CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Guanylate_cyc
EH2_k127_3752477_1	1123393.KB891329_gene1036	1.556e-96	325.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria,1KSY7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_3752477_9	1123392.AQWL01000011_gene2239	7.137e-31	128.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria,1KSZV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
EH2_k127_3752477_4	1123393.KB891329_gene1034	1.487e-68	241.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,1KSYH@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
EH2_k127_3752477_10	1123393.KB891329_gene1033	2.235e-18	94.0	COG1129@1|root,COG1129@2|Bacteria,1PAYN@1224|Proteobacteria,2WC7Z@28216|Betaproteobacteria,1KT7W@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3752477_3	1123392.AQWL01000011_gene2242	1.845e-85	294.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,1KS5S@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Mammalian cell entry related domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3752477_7	614083.AWQR01000040_gene756	8.516e-51	199.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,4AE2G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3752477_6	1476583.DEIPH_ctg026orf0070	2.027e-57	205.0	COG2391@1|root,COG2391@2|Bacteria,1WK5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_3752477_8	1406840.Q763_08075	1.339e-46	171.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,2NW8V@237|Flavobacterium	976|Bacteroidetes	S	Transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_3752477_5	292415.Tbd_0976	6.184e-68	235.0	COG3255@1|root,COG3255@2|Bacteria,1N5G0@1224|Proteobacteria,2W311@28216|Betaproteobacteria	28216|Betaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
EH2_k127_3759505_1	1121456.ATVA01000005_gene2974	1.055e-41	154.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2M9QR@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
EH2_k127_3759505_0	43989.cce_4499	8.91e-60	211.0	COG3812@1|root,COG3812@2|Bacteria,1G61H@1117|Cyanobacteria,3KJB7@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
EH2_k127_3759505_2	1215092.PA6_046_00180	1.252e-34	138.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1YKR1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
EH2_k127_3764945_1	748280.NH8B_1180	2.697e-38	149.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,2KQ0M@206351|Neisseriales	206351|Neisseriales	P	permease protein	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH2_k127_3764945_0	292415.Tbd_0990	6.584e-179	564.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1KRJA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
EH2_k127_3775243_3	555778.Hneap_1885	1.503e-13	79.0	COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,1X2B4@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_3775243_2	1123517.JOMR01000001_gene1464	5.137e-40	162.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,463MS@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_3775243_0	1123399.AQVE01000012_gene2901	1.319e-66	233.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,1SNIS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
EH2_k127_3775243_1	1123399.AQVE01000012_gene2902	1.676e-46	169.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
EH2_k127_3782696_0	292415.Tbd_0159	1.693e-196	615.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KRI8@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
EH2_k127_3782696_1	1163617.SCD_n02843	2.685e-105	353.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2VMQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Inositol-1-monophosphatase	suhB2	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
EH2_k127_3782696_2	1123393.KB891331_gene2914	1.801e-89	298.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,1KS28@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_3782696_3	1163617.SCD_n02841	2.929e-44	167.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
EH2_k127_3802442_3	94624.Bpet2108	1.463e-16	86.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria,3T297@506|Alcaligenaceae	28216|Betaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
EH2_k127_3802442_1	1210884.HG799462_gene8570	2.344e-64	226.0	COG0229@1|root,COG0229@2|Bacteria,2J37K@203682|Planctomycetes	203682|Planctomycetes	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
EH2_k127_3802442_4	713586.KB900536_gene2380	7.634e-11	64.0	2EJVT@1|root,33DKI@2|Bacteria,1NKVD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3802442_2	1123393.KB891329_gene928	6.66e-54	193.0	2EDED@1|root,337AR@2|Bacteria,1PWPZ@1224|Proteobacteria,2WC88@28216|Betaproteobacteria,1KT8C@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3802442_0	1123392.AQWL01000002_gene1833	1.346e-115	379.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1KRG4@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
EH2_k127_3813057_6	1042375.AFPL01000050_gene96	4.285e-61	216.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
EH2_k127_3813057_1	292415.Tbd_0384	3.974e-145	479.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,1KRQB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
EH2_k127_3813057_7	1123393.KB891330_gene738	4.201e-38	150.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria,1KS6V@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Outer membrane lipoprotein LolB	-	-	-	-	-	-	-	-	-	-	-	-	LolB
EH2_k127_3813057_2	1163617.SCD_n02623	1.413e-108	360.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
EH2_k127_3813057_0	292415.Tbd_0387	5.608e-171	541.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KRHN@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
EH2_k127_3813057_4	1123392.AQWL01000002_gene2122	4.807e-81	275.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,1KRND@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal L25p family	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
EH2_k127_3813057_3	62928.azo0753	1.698e-100	332.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,2KVUE@206389|Rhodocyclales	206389|Rhodocyclales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
EH2_k127_3813057_5	1123504.JQKD01000021_gene5656	4.71e-63	224.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,4A9MM@80864|Comamonadaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
EH2_k127_3822266_0	1123393.KB891316_gene1919	1.044e-188	600.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
EH2_k127_3822266_4	1163617.SCD_n02788	1.094e-45	171.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
EH2_k127_3822266_1	292415.Tbd_2508	3.758e-111	368.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1KRNZ@119069|Hydrogenophilales	119069|Hydrogenophilales	D	PP-loop family	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
EH2_k127_3822266_2	1236959.BAMT01000005_gene153	3.027e-100	336.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,2KKMZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
EH2_k127_3822266_3	1163617.SCD_n02773	1.901e-56	205.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
EH2_k127_3837971_4	292415.Tbd_2724	1.62e-55	201.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
EH2_k127_3837971_5	1163617.SCD_n02858	2.828e-31	126.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
EH2_k127_3837971_6	1288494.EBAPG3_10920	1.89e-06	61.0	2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria,373M2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3837971_0	292415.Tbd_2507	6.886e-218	691.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KSNF@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
EH2_k127_3837971_2	396588.Tgr7_1031	1.271e-95	322.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1WXFV@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
EH2_k127_3837971_1	1123392.AQWL01000003_gene491	1.591e-150	482.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KS1H@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
EH2_k127_3837971_3	887898.HMPREF0551_0442	2.193e-58	206.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,1K81Q@119060|Burkholderiaceae	28216|Betaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein b	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
EH2_k127_3867410_2	870187.Thini_2677	2.947e-108	358.0	COG0369@1|root,COG0369@2|Bacteria,1NCKQ@1224|Proteobacteria,1RR4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	1.14.13.208,1.18.1.2,1.8.1.2	ko:K00380,ko:K02641,ko:K15511	ko00195,ko00362,ko00920,ko01100,ko01120,map00195,map00362,map00920,map01100,map01120	M00176	R00858,R09555	RC00065,RC01739	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
EH2_k127_3867410_7	323261.Noc_2705	5.468e-15	84.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1WYY4@135613|Chromatiales	135613|Chromatiales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
EH2_k127_3867410_0	1123393.KB891316_gene1689	2.553e-247	771.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,1KRC2@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
EH2_k127_3867410_3	1163617.SCD_n00391	3.117e-105	347.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
EH2_k127_3867410_5	1049564.TevJSym_aw00360	1.603e-21	101.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH2_k127_3867410_6	1123393.KB891316_gene1691	2.624e-21	96.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KRWJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DNA gyrase inhibitor YacG	-	-	-	-	-	-	-	-	-	-	-	-	YacG
EH2_k127_3867410_4	522306.CAP2UW1_3027	4.311e-58	203.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KQ1R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
EH2_k127_3867410_1	748247.AZKH_1058	1.955e-133	428.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,2KVIA@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_3867419_0	1123392.AQWL01000018_gene70	4.945e-194	615.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,1KRDC@119069|Hydrogenophilales	119069|Hydrogenophilales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
EH2_k127_3867419_3	1123392.AQWL01000012_gene2472	1.577e-57	205.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1KS1D@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
EH2_k127_3867419_4	395494.Galf_1389	9.758e-48	183.0	COG5380@1|root,COG5380@2|Bacteria	2|Bacteria	O	lipid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_chap
EH2_k127_3867419_1	62928.azo0150	4.121e-186	595.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
EH2_k127_3867419_6	1123392.AQWL01000018_gene73	2.638e-35	135.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,1KTCQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
EH2_k127_3867419_2	1123392.AQWL01000018_gene74	2.407e-84	284.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,1KRNY@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
EH2_k127_3867419_5	265072.Mfla_2384	2.018e-35	136.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,2KM0Z@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
EH2_k127_3870260_3	1163617.SCD_n00169	1.444e-11	67.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
EH2_k127_3870260_2	382245.ASA_0454	3.318e-16	89.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	ybeQ	GO:0006950,GO:0006979,GO:0008150,GO:0050896	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
EH2_k127_3870260_0	1123517.JOMR01000001_gene934	5.471e-208	658.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1SYH6@1236|Gammaproteobacteria,463T0@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH2_k127_3870260_1	323848.Nmul_A0979	8.101e-44	161.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJDV@28216|Betaproteobacteria,372BR@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
EH2_k127_387877_2	563008.HMPREF0665_00029	2.22e-12	70.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,2FNSY@200643|Bacteroidia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
EH2_k127_387877_0	443144.GM21_2439	1.958e-107	359.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
EH2_k127_387877_1	404380.Gbem_1812	8.6e-57	209.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,43VQQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
EH2_k127_3905627_1	522306.CAP2UW1_2602	4.844e-26	109.0	COG2202@1|root,COG2703@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
EH2_k127_3905627_2	443144.GM21_2797	6.456e-22	106.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,42R1Q@68525|delta/epsilon subdivisions,2WN15@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_3905627_0	765913.ThidrDRAFT_3800	1.019e-54	209.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RQ6G@1236|Gammaproteobacteria,1WX95@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
EH2_k127_3920654_2	1123392.AQWL01000005_gene2866	6.08e-20	91.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,1KRW1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
EH2_k127_3920654_0	292415.Tbd_2134	7.422e-175	550.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,1KRB3@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
EH2_k127_3920654_1	1163617.SCD_n01994	1.161e-56	205.0	COG0517@1|root,COG0517@2|Bacteria,1RE9W@1224|Proteobacteria,2VSNZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
EH2_k127_3920654_3	1163617.SCD_n02541	8.919e-10	62.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH2_k127_3932285_3	1163617.SCD_n02937	4.731e-54	192.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
EH2_k127_3932285_1	522306.CAP2UW1_0302	3.439e-68	249.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,1KQ2M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
EH2_k127_3932285_2	1123392.AQWL01000002_gene1941	2.696e-65	237.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,1KSN5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH2_k127_3932285_0	582744.Msip34_1063	5.142e-187	599.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,2KM7U@206350|Nitrosomonadales	206350|Nitrosomonadales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
EH2_k127_3933899_0	265072.Mfla_0358	0.0	1091.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KM0Q@206350|Nitrosomonadales	206350|Nitrosomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
EH2_k127_3933899_1	640081.Dsui_0458	2.997e-116	378.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
EH2_k127_3933899_2	62928.azo3602	2.363e-30	123.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,2KXDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
EH2_k127_3933899_3	1485544.JQKP01000002_gene1449	1.258e-07	59.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2WCG6@28216|Betaproteobacteria,44W0X@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_393407_2	426114.THI_2193	2.761e-31	123.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KM9R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
EH2_k127_393407_1	1123393.KB891328_gene643	1.13e-152	491.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,1KSNH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	GTP-binding GTPase Middle Region	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
EH2_k127_393407_0	1163617.SCD_n01800	7.115e-163	522.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
EH2_k127_3937405_3	795666.MW7_1132	0.0001622	52.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
EH2_k127_3937405_0	1123393.KB891316_gene1145	2.057e-151	489.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KRES@119069|Hydrogenophilales	119069|Hydrogenophilales	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
EH2_k127_3937405_2	999541.bgla_1g32030	6.018e-29	127.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,1K0EI@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_3937405_1	204773.HEAR0844	3.539e-54	194.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,474BH@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
EH2_k127_3957385_6	1123392.AQWL01000005_gene3234	2.247e-60	215.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3957385_2	292415.Tbd_2489	2.491e-157	499.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KSA5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_3957385_9	292415.Tbd_2488	2.741e-44	164.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_3957385_10	1123392.AQWL01000005_gene3231	1.409e-41	160.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria,1KSNR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
EH2_k127_3957385_12	1123393.KB891316_gene1852	3.452e-14	75.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria,1KTEP@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_3957385_0	292415.Tbd_2485	3.596e-240	748.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,1KSCU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH2_k127_3957385_1	1123393.KB891316_gene1850	5.555e-229	711.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,1KSR2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
EH2_k127_3957385_5	765913.ThidrDRAFT_2034	2.558e-66	228.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1WY2D@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein TusD DsrE	dsrE	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
EH2_k127_3957385_8	292415.Tbd_2482	1.081e-55	197.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
EH2_k127_3957385_11	1123393.KB891316_gene1847	5.416e-40	150.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
EH2_k127_3957385_7	1123392.AQWL01000005_gene3224	1.244e-56	198.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
EH2_k127_3957385_3	292415.Tbd_2479	1.51e-115	377.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
EH2_k127_3957385_4	292415.Tbd_2478	1.453e-80	270.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,2VNTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
EH2_k127_3959862_2	265072.Mfla_1048	2.497e-16	79.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KMC7@206350|Nitrosomonadales	206350|Nitrosomonadales	E	amino acid-binding ACT domain protein	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
EH2_k127_3959862_0	265072.Mfla_0905	6.303e-224	702.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,2KMEQ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
EH2_k127_3959862_1	1000565.METUNv1_02902	1.441e-38	147.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,2KWVU@206389|Rhodocyclales	206389|Rhodocyclales	F	Guanyl-specific ribonuclease Sa	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
EH2_k127_3959862_3	85643.Tmz1t_1167	8.67e-15	82.0	COG2732@1|root,COG2732@2|Bacteria,1RD25@1224|Proteobacteria,2VWTV@28216|Betaproteobacteria,2M03K@206389|Rhodocyclales	206389|Rhodocyclales	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
EH2_k127_3970730_0	1123392.AQWL01000004_gene2701	3.607e-202	636.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,1KREF@119069|Hydrogenophilales	119069|Hydrogenophilales	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
EH2_k127_3970730_2	1123392.AQWL01000004_gene2702	4.401e-35	145.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KSP5@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
EH2_k127_3970730_1	292415.Tbd_0592	4.197e-61	217.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,1KRTF@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Tetratricopeptide repeat	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_8
EH2_k127_3984117_1	1121033.AUCF01000019_gene3705	3.332e-97	326.0	COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales	204441|Rhodospirillales	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
EH2_k127_3984117_0	1163617.SCD_n02021	6.656e-144	471.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_4098843_4	62928.azo3292	4.974e-41	153.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
EH2_k127_4098843_3	85643.Tmz1t_3614	1.462e-70	250.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
EH2_k127_4098843_2	1123393.KB891330_gene752	1.343e-90	304.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,1KSXN@119069|Hydrogenophilales	119069|Hydrogenophilales	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
EH2_k127_4098843_0	1123392.AQWL01000002_gene2110	1.621e-138	447.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,1KRA8@119069|Hydrogenophilales	119069|Hydrogenophilales	U	SRP54-type protein, helical bundle domain	-	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
EH2_k127_4098843_1	292415.Tbd_0377	1.654e-119	391.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,1KSAX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_4122386_2	1123487.KB892834_gene2997	1.004e-114	374.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
EH2_k127_4122386_1	1122604.JONR01000015_gene149	1.764e-117	394.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1X5FH@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
EH2_k127_4122386_8	1122603.ATVI01000006_gene825	5.15e-56	213.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1X5GK@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
EH2_k127_4122386_7	1123393.KB891332_gene2809	2.298e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,1R434@1224|Proteobacteria,2WEVM@28216|Betaproteobacteria,1KSZZ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH2_k127_4122386_6	1304883.KI912532_gene3042	3.404e-72	250.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,2KW25@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH2_k127_4122386_5	1163617.SCD_n01213	3.759e-81	276.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
EH2_k127_4122386_9	292415.Tbd_0600	1.062e-23	103.0	2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,2VYWR@28216|Betaproteobacteria,1KT93@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4122386_10	1123393.KB891328_gene640	7.678e-23	100.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria,2W5JW@28216|Betaproteobacteria,1KT9H@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4122386_4	292415.Tbd_0281	2.226e-86	290.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
EH2_k127_4122386_0	292415.Tbd_0282	1.129e-164	532.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,1KSI5@119069|Hydrogenophilales	119069|Hydrogenophilales	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR
EH2_k127_4122386_3	1123393.KB891330_gene819	1.695e-95	322.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,1KSF2@119069|Hydrogenophilales	119069|Hydrogenophilales	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
EH2_k127_4122386_11	29581.BW37_01045	8.173e-14	79.0	COG5338@1|root,COG5338@2|Bacteria,1QUYH@1224|Proteobacteria,2WGKN@28216|Betaproteobacteria,4791B@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4130037_1	1123392.AQWL01000004_gene2558	9.218e-112	363.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria,1KSUB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
EH2_k127_4130037_4	472759.Nhal_3472	2.818e-53	199.0	2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,1SBQY@1236|Gammaproteobacteria,1WZRS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4130037_2	640081.Dsui_1261	2.384e-87	297.0	COG0784@1|root,COG0784@2|Bacteria,1QWFW@1224|Proteobacteria,2VPCN@28216|Betaproteobacteria,2KVZ3@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_4130037_3	292415.Tbd_0747	2.089e-83	280.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1KSGX@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
EH2_k127_4130037_0	1123392.AQWL01000001_gene1357	3.642e-227	709.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase, U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
EH2_k127_4148411_0	1307759.JOMJ01000004_gene2828	3.356e-64	233.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
EH2_k127_4148411_1	1123392.AQWL01000001_gene1364	4.751e-25	115.0	2A61N@1|root,30UTY@2|Bacteria,1Q9UM@1224|Proteobacteria,2W6WQ@28216|Betaproteobacteria,1KTCD@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4148411_2	1384056.N787_13935	4.35e-10	66.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X525@135614|Xanthomonadales	135614|Xanthomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
EH2_k127_4148411_3	1313301.AUGC01000015_gene1876	3.758e-09	65.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
EH2_k127_415617_1	1523503.JPMY01000017_gene2882	7.444e-48	175.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,1RY43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
EH2_k127_415617_0	1123393.KB891317_gene2352	2.223e-95	315.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,1KRCA@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
EH2_k127_415617_2	296591.Bpro_4282	1.341e-33	140.0	COG3221@1|root,COG3221@2|Bacteria,1MYRC@1224|Proteobacteria,2VTJP@28216|Betaproteobacteria,4AEMW@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH2_k127_415617_3	1163617.SCD_n01279	7.474e-10	66.0	29460@1|root,2ZRKG@2|Bacteria,1PBM2@1224|Proteobacteria,2W5WD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	-
EH2_k127_4169442_3	522306.CAP2UW1_1272	3.018e-118	389.0	COG4313@1|root,COG4313@2|Bacteria,1PRCN@1224|Proteobacteria,2VQHT@28216|Betaproteobacteria,1KQK1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
EH2_k127_4169442_6	1144325.PMI22_00273	1.093e-17	85.0	2E43B@1|root,32YZP@2|Bacteria,1NG2F@1224|Proteobacteria,1SFP3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4169442_0	1095769.CAHF01000013_gene3396	5.164e-244	767.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,472BR@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
EH2_k127_4169442_1	62928.azo1497	1.023e-174	564.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,2KUA1@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH2_k127_4169442_2	261292.Nit79A3_0196	2.48e-130	434.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,371ZG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
EH2_k127_4169442_5	1163617.SCD_n00786	7.269e-82	279.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
EH2_k127_4169442_4	323848.Nmul_A1604	6.045e-94	315.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,3720W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
EH2_k127_4170350_3	1123392.AQWL01000005_gene3001	1.208e-24	113.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria,2VWBE@28216|Betaproteobacteria,1KT1N@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
EH2_k127_4170350_1	1123392.AQWL01000005_gene3065	7.138e-69	241.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,1KRYJ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Disulfide bond isomerase protein N-terminus	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
EH2_k127_4170350_0	1123367.C666_12935	1.51e-105	359.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,2KUAJ@206389|Rhodocyclales	206389|Rhodocyclales	C	Ubiquinone biosynthesis hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,SE
EH2_k127_4170350_2	292415.Tbd_2333	1.87e-31	125.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1KSHU@119069|Hydrogenophilales	119069|Hydrogenophilales	CH	FAD binding domain	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH2_k127_4181777_1	640081.Dsui_3403	1.071e-62	228.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,2KUGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971,DUF748
EH2_k127_4181777_0	1123392.AQWL01000011_gene2234	2.171e-125	410.0	COG4360@1|root,COG4360@2|Bacteria,1RB5I@1224|Proteobacteria,2W0KI@28216|Betaproteobacteria,1KS44@119069|Hydrogenophilales	119069|Hydrogenophilales	F	ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4206578_0	1122236.KB905141_gene1334	3.434e-45	181.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2VSKQ@28216|Betaproteobacteria,2KP39@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_4206578_1	497964.CfE428DRAFT_4814	2.97e-17	88.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia	2|Bacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
EH2_k127_4233613_0	1304883.KI912532_gene872	1.873e-113	374.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KUDV@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH2_k127_4233613_1	1163617.SCD_n01928	6.257e-38	154.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_4253947_4	292415.Tbd_1055	3.431e-16	79.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria,2VTFD@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
EH2_k127_4253947_3	1123392.AQWL01000005_gene3121	4.711e-44	164.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,1KRW8@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
EH2_k127_4253947_2	265072.Mfla_2327	3.465e-60	215.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,2KMN9@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
EH2_k127_4253947_1	1123392.AQWL01000005_gene3123	9.761e-64	227.0	28P17@1|root,2ZBXM@2|Bacteria,1RCPK@1224|Proteobacteria,2VZ64@28216|Betaproteobacteria,1KSBN@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4253947_0	1123392.AQWL01000005_gene3124	6.971e-152	488.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,1KRBP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
EH2_k127_4256625_2	279714.FuraDRAFT_3746	1.732e-26	111.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KQEW@206351|Neisseriales	206351|Neisseriales	I	squalene synthase HpnC	hpnC	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
EH2_k127_4256625_0	1123367.C666_02565	5.636e-115	377.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KUHC@206389|Rhodocyclales	206389|Rhodocyclales	I	Squalene synthase HpnD	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
EH2_k127_4256625_1	1236959.BAMT01000001_gene1547	3.578e-76	266.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,2KM1H@206350|Nitrosomonadales	206350|Nitrosomonadales	H	TIGRFAM squalene-associated FAD-dependent desaturase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
EH2_k127_4270331_6	748247.AZKH_3494	7.164e-66	227.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,2KUND@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
EH2_k127_4270331_7	1266925.JHVX01000015_gene223	7.231e-55	204.0	COG1502@1|root,COG1502@2|Bacteria,1RG6H@1224|Proteobacteria,2VTMJ@28216|Betaproteobacteria,37437@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
EH2_k127_4270331_2	292415.Tbd_2594	1.182e-183	581.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,1KSM9@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Transposase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
EH2_k127_4270331_10	882378.RBRH_00925	5.603e-24	103.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,1KA4N@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
EH2_k127_4270331_8	265072.Mfla_0312	2.617e-38	144.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,2KN2K@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
EH2_k127_4270331_5	1163617.SCD_n00750	1.088e-101	342.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
EH2_k127_4270331_3	1123368.AUIS01000005_gene483	6.867e-165	529.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,2NBWP@225057|Acidithiobacillales	225057|Acidithiobacillales	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
EH2_k127_4270331_4	1123368.AUIS01000005_gene484	7.908e-129	420.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,2NC9T@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
EH2_k127_4270331_0	1123368.AUIS01000005_gene485	3.708e-235	736.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,2NBSD@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
EH2_k127_4270331_1	396588.Tgr7_2035	1.159e-200	634.0	COG3395@1|root,COG3395@2|Bacteria,1QKU1@1224|Proteobacteria,1TIZB@1236|Gammaproteobacteria,1WXF7@135613|Chromatiales	135613|Chromatiales	S	Type III effector Hrp-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
EH2_k127_4270331_9	1123368.AUIS01000005_gene487	9.174e-25	104.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RYC8@1236|Gammaproteobacteria,2NC3Q@225057|Acidithiobacillales	225057|Acidithiobacillales	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
EH2_k127_4287948_1	1123392.AQWL01000006_gene684	1.261e-45	171.0	COG0784@1|root,COG2770@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2770@2|Bacteria,COG4251@2|Bacteria,1QTVB@1224|Proteobacteria,2WHE1@28216|Betaproteobacteria,1KSTV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
EH2_k127_4287948_0	265072.Mfla_1099	4.897e-92	311.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,2KKJY@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_4287948_2	278957.ABEA03000218_gene222	7.102e-45	164.0	COG1028@1|root,COG1028@2|Bacteria,46U4P@74201|Verrucomicrobia,3K749@414999|Opitutae	414999|Opitutae	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_429305_1	640081.Dsui_0759	4.116e-30	127.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,2KWYV@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_429305_0	1123393.KB891331_gene2919	4.687e-304	955.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
EH2_k127_4326262_3	909663.KI867150_gene1970	9.102e-36	139.0	COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,42UAH@68525|delta/epsilon subdivisions,2WQUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellar FlbT family protein	flbT	-	-	ko:K06601	-	-	-	-	ko00000,ko02035	-	-	-	FlbT
EH2_k127_4326262_2	316067.Geob_0643	2.41e-72	254.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
EH2_k127_4326262_4	316067.Geob_0646	1.353e-26	113.0	COG5442@1|root,COG5442@2|Bacteria,1REZ8@1224|Proteobacteria,42W1U@68525|delta/epsilon subdivisions,2WRE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar protein FlaF	-	-	-	ko:K06602	-	-	-	-	ko00000,ko02035	-	-	-	FlaF
EH2_k127_4326262_1	316067.Geob_0643	1.576e-73	256.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
EH2_k127_4326262_0	864702.OsccyDRAFT_2446	9.822e-74	278.0	COG0457@1|root,COG2520@1|root,COG0457@2|Bacteria,COG2520@2|Bacteria,1G193@1117|Cyanobacteria,1HE9A@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_8
EH2_k127_4326990_5	497321.C664_10987	1.875e-122	399.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,2KV2R@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC1	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_4326990_6	29581.BW37_02228	2.128e-90	313.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,472S1@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
EH2_k127_4326990_2	1163617.SCD_n01032	1.734e-190	604.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
EH2_k127_4326990_8	159087.Daro_1279	2.048e-80	276.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,2KUWK@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
EH2_k127_4326990_0	292415.Tbd_0956	2.223e-293	908.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,1KSH9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
EH2_k127_4326990_10	265072.Mfla_1070	3.488e-38	148.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,2KN0D@206350|Nitrosomonadales	206350|Nitrosomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_4326990_11	1288494.EBAPG3_23280	2.177e-12	70.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,373IP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
EH2_k127_4326990_4	1123393.KB891317_gene2459	2.251e-126	416.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,1KS26@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
EH2_k127_4326990_7	754436.JCM19237_4205	3.814e-85	295.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XUKK@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
EH2_k127_4326990_1	580332.Slit_1377	1.257e-215	685.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,44VH2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
EH2_k127_4326990_3	292415.Tbd_0964	7.214e-159	507.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,1KRGN@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
EH2_k127_4326990_9	1304883.KI912532_gene2974	4.654e-46	171.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase	dnaL	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
EH2_k127_4370749_1	305700.B447_19809	1.403e-193	607.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
EH2_k127_4370749_0	1304883.KI912532_gene603	5.398e-221	691.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,2KV7G@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
EH2_k127_4370749_3	1163617.SCD_n00308	1.045e-101	342.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
EH2_k127_4370749_6	522306.CAP2UW1_4174	4.2e-32	132.0	COG0454@1|root,COG0456@2|Bacteria,1RJDS@1224|Proteobacteria,2VSVF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
EH2_k127_4370749_5	292415.Tbd_2525	1.706e-53	191.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
EH2_k127_4370749_4	1215092.PA6_009_01300	6.832e-78	264.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,1S7AB@1236|Gammaproteobacteria,1YJFK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4370749_2	292415.Tbd_2526	4.683e-121	399.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KRE1@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Diaminopimelate epimerase	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
EH2_k127_4370749_7	1163617.SCD_n00312	4.128e-16	88.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
EH2_k127_4403704_0	1123392.AQWL01000003_gene290	1.109e-309	957.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Inorganic H+ pyrophosphatase	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
EH2_k127_4403704_3	1123393.KB891333_gene2506	1.488e-32	128.0	2ESIQ@1|root,33K3E@2|Bacteria,1NJ20@1224|Proteobacteria,2WCCZ@28216|Betaproteobacteria,1KTFU@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4403704_1	292415.Tbd_1502	4.527e-253	783.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
EH2_k127_4403704_4	292415.Tbd_1503	1.725e-31	128.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4403704_2	1163617.SCD_n01890	1.865e-63	219.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
EH2_k127_4405180_1	1123399.AQVE01000041_gene3613	4.102e-162	513.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,461YM@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
EH2_k127_4405180_2	1163617.SCD_n02290	7.835e-147	492.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
EH2_k127_4405180_6	864051.BurJ1DRAFT_0534	2.782e-52	196.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,2VX13@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
EH2_k127_4405180_4	243365.CV_0562	1.452e-109	359.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KQ47@206351|Neisseriales	206351|Neisseriales	T	Transcriptional regulatory protein, C terminal	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_4405180_3	1123392.AQWL01000002_gene1969	7.901e-121	402.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,1KSVV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA
EH2_k127_4405180_5	1283300.ATXB01000001_gene514	2.552e-52	189.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XFA7@135618|Methylococcales	135618|Methylococcales	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
EH2_k127_4405180_0	159087.Daro_4121	1.275e-207	653.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH2_k127_4410696_3	1267005.KB911264_gene3144	5.189e-20	91.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria,3N86G@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Pirin	MA20_06040	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
EH2_k127_4410696_2	1000565.METUNv1_02160	2.94e-51	192.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria,2M011@206389|Rhodocyclales	206389|Rhodocyclales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
EH2_k127_4410696_1	1487953.JMKF01000008_gene6044	8.399e-62	218.0	COG3803@1|root,COG3803@2|Bacteria,1G55K@1117|Cyanobacteria,1HAXI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
EH2_k127_4410696_0	1163617.SCD_n00300	7.042e-81	271.0	2DS8H@1|root,32USH@2|Bacteria,1RCDN@1224|Proteobacteria,2W06A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
EH2_k127_4419408_2	1163617.SCD_n01223	1.901e-121	394.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
EH2_k127_4419408_1	1163617.SCD_n01222	3.049e-131	425.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	cheV1-2	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
EH2_k127_4419408_4	1163617.SCD_n01221	2.349e-65	224.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_4419408_3	1163617.SCD_n01220	5.242e-73	254.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
EH2_k127_4419408_5	398525.KB900701_gene7029	0.0002009	46.0	2AJ03@1|root,319I4@2|Bacteria,1NSR6@1224|Proteobacteria,2UR2W@28211|Alphaproteobacteria,3K3BF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4419408_0	1121004.ATVC01000004_gene1439	4.872e-196	629.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KU4G@206351|Neisseriales	206351|Neisseriales	NT	Chemotaxis protein CheA	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH2_k127_4419408_6	1198452.Jab_2c15650	0.0008483	42.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria,478KJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_4425459_3	497321.C664_02195	5.574e-29	121.0	COG3109@1|root,COG3109@2|Bacteria,1PS29@1224|Proteobacteria,2VU30@28216|Betaproteobacteria,2KWZI@206389|Rhodocyclales	206389|Rhodocyclales	T	activator of osmoprotectant transporter ProP	proQ	-	-	ko:K03607	-	-	-	-	ko00000	-	-	-	ProQ
EH2_k127_4425459_4	1209072.ALBT01000013_gene3621	1.412e-20	98.0	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	VRP1
EH2_k127_4425459_0	497321.C664_13739	0.0	1055.0	COG1032@1|root,COG1032@2|Bacteria,1PK5W@1224|Proteobacteria,2VJIN@28216|Betaproteobacteria,2KVTD@206389|Rhodocyclales	206389|Rhodocyclales	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
EH2_k127_4425459_2	1348657.M622_08670	6.16e-59	210.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,2KWC2@206389|Rhodocyclales	206389|Rhodocyclales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
EH2_k127_4425459_1	522306.CAP2UW1_0503	4.106e-140	448.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,1KPND@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
EH2_k127_4428541_1	1123392.AQWL01000002_gene1960	8.359e-109	370.0	2DBH8@1|root,2Z982@2|Bacteria,1MXUE@1224|Proteobacteria,2VP20@28216|Betaproteobacteria,1KSZB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4428541_2	1123392.AQWL01000002_gene1959	3.733e-61	223.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,1KRQ3@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Shikimate kinase	-	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
EH2_k127_4428541_3	748280.NH8B_0218	4.68e-06	54.0	COG4701@1|root,COG4701@2|Bacteria,1PK4W@1224|Proteobacteria,2WE1P@28216|Betaproteobacteria,2KSAH@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
EH2_k127_4428541_0	1123393.KB891331_gene2948	0.0	1202.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KS70@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
EH2_k127_4428743_0	243365.CV_2520	3.552e-223	714.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KPKW@206351|Neisseriales	206351|Neisseriales	S	ABC transporter, ATP-binding protein	abcZ	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
EH2_k127_4428743_4	1163617.SCD_n00979	1.636e-20	97.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,2VY9Z@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM zinc finger, DksA TraR C4-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
EH2_k127_4428743_2	1163617.SCD_n00221	1.88e-118	418.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,Response_reg
EH2_k127_4428743_3	1232410.KI421426_gene1467	9.046e-22	103.0	2E5SP@1|root,330H2@2|Bacteria,1NDBY@1224|Proteobacteria	1224|Proteobacteria	S	YMGG-like Gly-zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA,Gly-zipper_YMGG
EH2_k127_4428743_1	85643.Tmz1t_1473	8.784e-170	542.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
EH2_k127_4474748_3	1123392.AQWL01000004_gene2686	8.19e-31	123.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KS8B@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ribonuclease B OB domain	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
EH2_k127_4474748_1	204773.HEAR1278	2.058e-85	289.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,472IM@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
EH2_k127_4474748_2	292415.Tbd_0777	1.905e-64	237.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,1KRP4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
EH2_k127_4474748_0	1163617.SCD_n01661	1.076e-100	335.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	mtaP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
EH2_k127_4474752_0	292415.Tbd_0608	1.263e-276	861.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KS8B@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ribonuclease B OB domain	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
EH2_k127_4485486_0	1123392.AQWL01000008_gene1189	1.153e-216	676.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1KS2Q@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
EH2_k127_4485486_3	1123392.AQWL01000014_gene797	1.19e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KTB5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
EH2_k127_4485486_1	1149133.ppKF707_1768	8.744e-72	249.0	COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,1SA20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
EH2_k127_4485486_2	292415.Tbd_1536	1.512e-50	180.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KRK3@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
EH2_k127_449948_0	1163617.SCD_n01237	3.524e-95	317.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
EH2_k127_449948_4	1247649.D560_3538	5.772e-24	109.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria,3T4FK@506|Alcaligenaceae	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
EH2_k127_449948_1	335283.Neut_2061	1.841e-58	216.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,37217@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
EH2_k127_449948_2	1458357.BG58_11590	8.182e-53	191.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
EH2_k127_449948_3	1123367.C666_07935	3.196e-25	106.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
EH2_k127_4500409_0	1120999.JONM01000001_gene1226	2.181e-133	443.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQNU@206351|Neisseriales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg
EH2_k127_4500409_4	1150469.RSPPHO_02505	3.329e-43	169.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2UK6R@28211|Alphaproteobacteria,2JUP0@204441|Rhodospirillales	204441|Rhodospirillales	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_4500409_5	1150469.RSPPHO_00885	7.326e-19	90.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQTN@28211|Alphaproteobacteria,2JPPH@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
EH2_k127_4500409_2	748247.AZKH_p0155	3.737e-89	303.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
EH2_k127_4500409_1	1454004.AW11_04024	1.445e-99	346.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,1KQFW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
EH2_k127_4500409_3	522306.CAP2UW1_2148	1.628e-73	250.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria,1KQ7Z@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
EH2_k127_4505851_1	640081.Dsui_1050	6.656e-96	322.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
EH2_k127_4505851_0	748247.AZKH_0674	5.295e-207	652.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_4505851_2	292415.Tbd_0082	5.5e-84	288.0	COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,2VVPY@28216|Betaproteobacteria,1KSG3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
EH2_k127_4505851_4	748247.AZKH_4606	7.11e-08	58.0	COG2703@1|root,COG2703@2|Bacteria,1P42M@1224|Proteobacteria,2W6C4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	oxygen carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4505851_3	768671.ThimaDRAFT_1043	3.46e-49	186.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1WXUX@135613|Chromatiales	135613|Chromatiales	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
EH2_k127_4510645_2	1123393.KB891329_gene1050	8.599e-30	128.0	COG5001@1|root,COG5001@2|Bacteria,1R59J@1224|Proteobacteria,2W00Q@28216|Betaproteobacteria,1KSEW@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_4510645_1	1123392.AQWL01000011_gene2223	2.929e-68	242.0	COG1073@1|root,COG1073@2|Bacteria,1RD2N@1224|Proteobacteria,2W2I1@28216|Betaproteobacteria,1KS8X@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF1749)	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4510645_0	1163617.SCD_n01598	3.982e-248	782.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria	28216|Betaproteobacteria	KL	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
EH2_k127_4510645_3	1123392.AQWL01000008_gene1215	2.618e-10	64.0	2DMN0@1|root,32SKB@2|Bacteria,1N2XU@1224|Proteobacteria,2VUWF@28216|Betaproteobacteria,1KTFG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
EH2_k127_4515408_1	1485544.JQKP01000015_gene2068	8.398e-90	299.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,44V94@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
EH2_k127_4515408_0	1158762.KB898038_gene2122	3.394e-90	315.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WZVV@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,EAL,GGDEF,PAS,PAS_4
EH2_k127_4527081_0	395494.Galf_1411	0.0	1061.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
EH2_k127_4527081_1	519989.ECTPHS_06202	6.73e-115	380.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_4527081_2	292415.Tbd_1837	4.242e-54	194.0	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,2VTZ3@28216|Betaproteobacteria,1KT83@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
EH2_k127_4527081_3	1123392.AQWL01000001_gene1596	1.079e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria,1KSS0@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_4527081_4	1163617.SCD_n01930	5.46e-22	102.0	COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria	28216|Betaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4558570_1	1163617.SCD_n00622	3.47e-122	392.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
EH2_k127_4558570_2	1163617.SCD_n00621	2.7e-78	263.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
EH2_k127_4558570_3	1000565.METUNv1_02258	9.796e-67	228.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,2KW8M@206389|Rhodocyclales	206389|Rhodocyclales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
EH2_k127_4558570_0	1123393.KB891319_gene715	0.0	1834.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,1KS99@119069|Hydrogenophilales	119069|Hydrogenophilales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
EH2_k127_456025_0	640081.Dsui_0581	2.225e-87	291.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,2KUW6@206389|Rhodocyclales	206389|Rhodocyclales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
EH2_k127_456025_3	75379.Tint_0683	4.385e-51	195.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,1KM3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	hydG	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
EH2_k127_456025_1	426114.THI_0870	3.774e-68	249.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,1KM5R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
EH2_k127_456025_2	1485544.JQKP01000001_gene894	9.848e-56	197.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VK3H@28216|Betaproteobacteria,44V66@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Amidase	atzF	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
EH2_k127_4585722_0	292415.Tbd_2101	1.199e-164	522.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KS3E@119069|Hydrogenophilales	119069|Hydrogenophilales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
EH2_k127_4585722_1	1163617.SCD_n01786	2.062e-125	412.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
EH2_k127_4585722_2	1123392.AQWL01000005_gene2955	7.037e-108	370.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,1KREE@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
EH2_k127_4585722_3	292415.Tbd_0448	2.316e-51	189.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,2W98Q@28216|Betaproteobacteria,1KSVT@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
EH2_k127_4588151_8	1163617.SCD_n00013	2.715e-42	162.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
EH2_k127_4588151_10	757424.Hsero_0071	7.46e-28	121.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,474NK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
EH2_k127_4588151_1	557598.LHK_00061	6.509e-124	410.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,2KQCQ@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
EH2_k127_4588151_4	1120999.JONM01000013_gene2124	5.433e-59	221.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KQQD@206351|Neisseriales	1224|Proteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH2_k127_4588151_0	1472716.KBK24_0115570	9.993e-213	670.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1K14Y@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_4588151_3	292415.Tbd_0247	6.979e-74	262.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,1KSQF@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
EH2_k127_4588151_2	1123392.AQWL01000002_gene2003	4.94e-85	288.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,1KRJG@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
EH2_k127_4588151_7	292415.Tbd_0249	5.164e-50	190.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VW39@28216|Betaproteobacteria,1KS2K@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
EH2_k127_4588151_9	292415.Tbd_0250	1.333e-30	138.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
EH2_k127_4588151_5	640081.Dsui_0447	2.113e-57	209.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,2KWCR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
EH2_k127_4588151_6	62928.azo0709	1.359e-54	199.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,2KVMW@206389|Rhodocyclales	206389|Rhodocyclales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
EH2_k127_4603134_0	396588.Tgr7_3302	1.983e-295	914.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
EH2_k127_4603134_3	1235457.C404_22520	1.48e-190	606.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,1K0PE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
EH2_k127_4603134_10	1123393.KB891332_gene2803	3.383e-55	196.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KRPP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
EH2_k127_4603134_2	292415.Tbd_2797	6.017e-263	813.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1KS24@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
EH2_k127_4603134_4	292415.Tbd_2798	6.39e-132	428.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,1KSC4@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
EH2_k127_4603134_1	323848.Nmul_A0308	2.959e-281	869.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,371UU@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
EH2_k127_4603134_11	323848.Nmul_A0307	7.217e-48	177.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,3737S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
EH2_k127_4603134_9	1123392.AQWL01000013_gene2377	3.825e-62	217.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,1KS17@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
EH2_k127_4603134_12	1123392.AQWL01000013_gene2376	2.09e-34	132.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
EH2_k127_4603134_5	292415.Tbd_2803	3.026e-129	418.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
EH2_k127_4603134_14	1123392.AQWL01000013_gene2374	4.591e-07	56.0	2AFZN@1|root,3163M@2|Bacteria,1PWSS@1224|Proteobacteria,2WCBE@28216|Betaproteobacteria,1KTD3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATP synthase I chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
EH2_k127_4603134_6	159087.Daro_4106	1.991e-107	355.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
EH2_k127_4603134_7	335283.Neut_2435	3.171e-102	339.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
EH2_k127_4603134_8	1123393.KB891332_gene2792	2.777e-65	233.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,1KRP8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	rRNA small subunit methyltransferase G	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
EH2_k127_4603134_13	1247726.MIM_c40780	1.231e-27	113.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,3T2SX@506|Alcaligenaceae	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
EH2_k127_4615456_0	546274.EIKCOROL_00316	1.994e-192	610.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KPTA@206351|Neisseriales	206351|Neisseriales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
EH2_k127_4615456_1	1121035.AUCH01000002_gene1588	3.278e-42	166.0	COG3221@1|root,COG3221@2|Bacteria,1R49P@1224|Proteobacteria,2VN1C@28216|Betaproteobacteria,2KVS5@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH2_k127_4619264_0	1123393.KB891330_gene901	6.997e-154	515.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
EH2_k127_4619264_1	1123393.KB891332_gene2769	4.869e-06	49.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,2W4VG@28216|Betaproteobacteria,1KT4V@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4630890_3	748280.NH8B_1075	9.957e-64	222.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,2KR2P@206351|Neisseriales	206351|Neisseriales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
EH2_k127_4630890_5	1304883.KI912532_gene887	8.687e-17	88.0	2EGQC@1|root,33AGI@2|Bacteria,1NGA3@1224|Proteobacteria,2VY93@28216|Betaproteobacteria,2KZKF@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
EH2_k127_4630890_2	857087.Metme_2779	2.605e-70	244.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,1S5B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4630890_4	1121035.AUCH01000004_gene298	8.616e-21	96.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KXFI@206389|Rhodocyclales	206389|Rhodocyclales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_4630890_0	1123392.AQWL01000014_gene802	2.397e-198	626.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
EH2_k127_4630890_1	1123392.AQWL01000014_gene801	9.967e-73	249.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
EH2_k127_4647467_1	1173024.KI912151_gene1625	5.204e-235	738.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
EH2_k127_4647467_0	1288494.EBAPG3_24420	0.0	1343.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,3720I@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
EH2_k127_4647467_3	640081.Dsui_1895	6.723e-75	255.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,2KYIA@206389|Rhodocyclales	206389|Rhodocyclales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
EH2_k127_4647467_4	640081.Dsui_1894	1.615e-63	228.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria,2KW5E@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4647467_5	640081.Dsui_2222	2.381e-59	216.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
EH2_k127_4647467_2	1163617.SCD_n01830	1.002e-216	688.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
EH2_k127_4653370_1	1163617.SCD_n01467	1.112e-29	122.0	COG0745@1|root,COG0745@2|Bacteria,1RETP@1224|Proteobacteria,2WGYY@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_4653370_0	85643.Tmz1t_3203	2.237e-313	974.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
EH2_k127_467298_1	1163617.SCD_n02542	5.56e-15	84.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
EH2_k127_467298_0	156889.Mmc1_2003	7.819e-105	359.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
EH2_k127_4715905_5	765913.ThidrDRAFT_2081	3.579e-24	104.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1WXDF@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
EH2_k127_4715905_0	1163617.SCD_n02840	2.703e-169	542.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
EH2_k127_4715905_3	159087.Daro_4085	4.559e-42	169.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,2KWYV@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH2_k127_4715905_1	640081.Dsui_0760	4.948e-165	541.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,2KXST@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	EAL,GGDEF,HAMP,PAS_8
EH2_k127_4715905_4	640081.Dsui_0759	1.095e-34	145.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,2KWYV@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_4715905_2	1123393.KB891331_gene2919	9.342e-116	391.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
EH2_k127_4717551_0	859657.RPSI07_2076	4.428e-296	922.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,1K43X@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
EH2_k127_4717551_2	497321.C664_12330	7.895e-32	130.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales	206389|Rhodocyclales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
EH2_k127_4717551_1	305700.B447_03748	1.561e-96	321.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,2KVRT@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
EH2_k127_4748538_5	292415.Tbd_1763	2.286e-39	158.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
EH2_k127_4748538_4	1123393.KB891316_gene1872	5.215e-90	306.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,1KSBX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
EH2_k127_4748538_2	292415.Tbd_2504	1.869e-109	360.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,1KSYB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Shikimate dehydrogenase substrate binding domain	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
EH2_k127_4748538_0	75379.Tint_1419	3.648e-272	841.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1KJNG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
EH2_k127_4748538_3	1163617.SCD_n02728	7.669e-101	349.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
EH2_k127_4748538_6	1123392.AQWL01000005_gene3246	4.652e-20	96.0	2EBVX@1|root,335VA@2|Bacteria,1PSUJ@1224|Proteobacteria,2VXJY@28216|Betaproteobacteria,1KSYQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
EH2_k127_4748538_1	1163617.SCD_n02117	8.683e-164	524.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
EH2_k127_4783362_1	1304883.KI912532_gene1783	3.979e-82	280.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,2KUYG@206389|Rhodocyclales	206389|Rhodocyclales	C	Respiratory-chain NADH dehydrogenase	hoxF	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
EH2_k127_4783362_0	1485544.JQKP01000002_gene1406	2.534e-221	709.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
EH2_k127_4783362_2	1485544.JQKP01000011_gene741	6.12e-53	195.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,44VJM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
EH2_k127_4803340_7	1158292.JPOE01000005_gene548	0.0006291	42.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,1KP9N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18306	ko02024,map02024	M00644	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.20,2.A.6.2.32,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
EH2_k127_4803340_0	1123368.AUIS01000003_gene1734	0.0	1453.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2NC0D@225057|Acidithiobacillales	225057|Acidithiobacillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_4803340_6	1123392.AQWL01000005_gene3138	1.176e-22	98.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,1KRVZ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
EH2_k127_4803340_4	1163617.SCD_n02693	8.41e-41	154.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
EH2_k127_4803340_5	757424.Hsero_0161	4.32e-39	146.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
EH2_k127_4803340_2	1538295.JY96_02090	1.841e-60	212.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,1KM2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
EH2_k127_4803340_3	159087.Daro_0613	4.483e-52	191.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,2KW5X@206389|Rhodocyclales	206389|Rhodocyclales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
EH2_k127_4803340_1	1163617.SCD_n02688	1.661e-80	275.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
EH2_k127_4810492_0	395494.Galf_2887	4.301e-288	898.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
EH2_k127_4810492_1	1163617.SCD_n01637	2.672e-85	284.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methionine aminopeptidase	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
EH2_k127_4830792_2	1123368.AUIS01000005_gene488	3.128e-11	64.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1SB98@1236|Gammaproteobacteria,2NCIT@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
EH2_k127_4830792_1	292415.Tbd_1575	1.559e-31	131.0	2CHMP@1|root,2ZJFK@2|Bacteria,1P479@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4830792_0	1266925.JHVX01000006_gene2160	2.308e-106	352.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,3723U@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
EH2_k127_4865363_3	443143.GM18_0163	6.256e-18	87.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria,42YX0@68525|delta/epsilon subdivisions,2WTXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
EH2_k127_4865363_1	1123393.KB891328_gene550	9.653e-43	160.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,1KRV8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	S4
EH2_k127_4865363_2	1123393.KB891316_gene1891	4.65e-23	106.0	2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,2WC53@28216|Betaproteobacteria,1KT3Z@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4865363_0	743299.Acife_2026	1.25e-77	265.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,2ND1R@225057|Acidithiobacillales	225057|Acidithiobacillales	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
EH2_k127_4884924_0	292415.Tbd_0989	4.765e-155	499.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,1KS05@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH2_k127_4884924_1	1255043.TVNIR_0499	1.891e-86	293.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1WX9E@135613|Chromatiales	135613|Chromatiales	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
EH2_k127_488966_3	1123401.JHYQ01000028_gene3153	2.119e-73	258.0	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
EH2_k127_488966_1	1123228.AUIH01000008_gene2407	8.498e-111	366.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XH5C@135619|Oceanospirillales	135619|Oceanospirillales	P	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_488966_4	98439.AJLL01000085_gene4555	1.019e-41	160.0	COG2391@1|root,COG2391@2|Bacteria,1G6M9@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_488966_5	195250.CM001776_gene3491	4.771e-41	160.0	COG2391@1|root,COG2391@2|Bacteria,1G7H1@1117|Cyanobacteria,1H2AB@1129|Synechococcus	1117|Cyanobacteria	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_488966_7	1382356.JQMP01000003_gene1440	2.671e-28	124.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
EH2_k127_488966_2	717606.PaecuDRAFT_4792	3.816e-77	271.0	COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,26QEB@186822|Paenibacillaceae	91061|Bacilli	C	nitroreductase	frp	-	-	-	-	-	-	-	-	-	-	iYO844.BSU07830	Nitroreductase
EH2_k127_488966_8	1046714.AMRX01000001_gene1824	4.319e-13	74.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
EH2_k127_488966_0	1000565.METUNv1_04023	9.884e-151	492.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VJK2@28216|Betaproteobacteria,2KUNA@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_488966_6	75379.Tint_2894	1.577e-30	125.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2VVTK@28216|Betaproteobacteria,1KMJG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
EH2_k127_488966_9	666681.M301_1757	4.606e-12	71.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,2KNKP@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
EH2_k127_4900740_0	322710.Avin_29240	7.439e-199	627.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
EH2_k127_4900740_2	1123392.AQWL01000002_gene1990	1.311e-54	194.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria,1KT1E@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_4900740_3	1123368.AUIS01000023_gene901	4.341e-39	150.0	2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4900740_4	1137799.GZ78_00170	1.293e-29	131.0	2BZY2@1|root,2ZMII@2|Bacteria,1P6VB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4900740_1	1137799.GZ78_00175	6.303e-78	274.0	COG4783@1|root,COG4783@2|Bacteria,1RAJB@1224|Proteobacteria,1SA1F@1236|Gammaproteobacteria,1XPS8@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
EH2_k127_4916942_3	748247.AZKH_1542	1.114e-49	183.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,2KXSX@206389|Rhodocyclales	206389|Rhodocyclales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
EH2_k127_4916942_1	1123393.KB891326_gene65	5.454e-138	452.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,2VNEE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
EH2_k127_4916942_0	1123393.KB891326_gene66	2.227e-225	707.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2VJP0@28216|Betaproteobacteria,1KS9Q@119069|Hydrogenophilales	119069|Hydrogenophilales	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
EH2_k127_4916942_2	1123368.AUIS01000003_gene1814	9.677e-88	291.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,1SNN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
EH2_k127_4971716_0	1458357.BG58_40540	8.549e-103	348.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2VR2P@28216|Betaproteobacteria,1K78M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
EH2_k127_4971716_3	1123393.KB891331_gene2982	2.49e-17	91.0	2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_4971716_1	1384054.N790_07735	1.08e-19	94.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1X82G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
EH2_k127_4971716_2	261292.Nit79A3_1602	9.148e-19	87.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,371NA@32003|Nitrosomonadales	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
EH2_k127_5028043_0	1000565.METUNv1_02785	1.323e-119	392.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,2KXF8@206389|Rhodocyclales	206389|Rhodocyclales	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
EH2_k127_5028043_1	1120999.JONM01000008_gene2019	2.201e-30	125.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KPRE@206351|Neisseriales	206351|Neisseriales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
EH2_k127_5055498_4	292415.Tbd_0455	1.113e-46	168.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KRDK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
EH2_k127_5055498_2	1123393.KB891318_gene2183	1.639e-64	222.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1KRMF@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
EH2_k127_5055498_0	62928.azo2760	1.767e-78	265.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,2KW9N@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
EH2_k127_5055498_1	580332.Slit_2472	3.07e-68	244.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
EH2_k127_5055498_3	1485544.JQKP01000002_gene1365	3.195e-64	222.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
EH2_k127_5066505_3	1123392.AQWL01000007_gene929	3.346e-64	222.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,1KSEU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Type I GTP cyclohydrolase folE2	-	-	-	-	-	-	-	-	-	-	-	-	GCHY-1
EH2_k127_5066505_0	1123392.AQWL01000009_gene1110	4.831e-283	882.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,1KSFP@119069|Hydrogenophilales	119069|Hydrogenophilales	HI	Transketolase, pyrimidine binding domain	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
EH2_k127_5066505_2	1123393.KB891317_gene2379	2.93e-108	362.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,1KRGJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
EH2_k127_5066505_4	580332.Slit_0704	6.689e-18	87.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,44W3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
EH2_k127_5066505_5	1217718.ALOU01000071_gene5062	9.805e-05	55.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,2VRHM@28216|Betaproteobacteria,1K4AB@119060|Burkholderiaceae	28216|Betaproteobacteria	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
EH2_k127_5066505_1	1163617.SCD_n02447	1.738e-202	638.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_5084180_1	1163617.SCD_n00763	1.985e-171	545.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,2VNZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
EH2_k127_5084180_2	1163617.SCD_n00762	1.67e-145	467.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VHPC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	formate dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
EH2_k127_5084180_0	1163617.SCD_n00761	8.458e-184	583.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH2_k127_5091841_2	292415.Tbd_0551	5.876e-47	171.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,1KS6P@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_5091841_1	1123393.KB891328_gene593	9.211e-103	354.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VS5V@28216|Betaproteobacteria,1KSNQ@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5091841_0	1121035.AUCH01000015_gene2586	0.0	1274.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,2KVJ1@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
EH2_k127_5145133_2	1158292.JPOE01000005_gene304	7.437e-119	388.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1KJXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
EH2_k127_5145133_8	1415780.JPOG01000001_gene876	2.838e-26	111.0	COG2916@1|root,COG2916@2|Bacteria,1N7YA@1224|Proteobacteria,1SFZZ@1236|Gammaproteobacteria,1X88J@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain in histone-like proteins of HNS family	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
EH2_k127_5145133_4	497321.C664_01800	2.716e-66	229.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,2KW90@206389|Rhodocyclales	206389|Rhodocyclales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
EH2_k127_5145133_5	1304883.KI912532_gene2517	2.14e-64	223.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,2KWDI@206389|Rhodocyclales	206389|Rhodocyclales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
EH2_k127_5145133_6	292415.Tbd_1000	2.755e-48	179.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,1KTBK@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Small MutS-related domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
EH2_k127_5145133_1	1121035.AUCH01000017_gene2248	1.351e-162	516.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
EH2_k127_5145133_0	85643.Tmz1t_1764	4.421e-307	958.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,2KVTG@206389|Rhodocyclales	206389|Rhodocyclales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
EH2_k127_5145133_3	159087.Daro_1296	1.25e-73	252.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
EH2_k127_5145133_7	292415.Tbd_1441	6.428e-43	160.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
EH2_k127_5145133_9	883126.HMPREF9710_03912	1.149e-14	73.0	COG2165@1|root,COG2165@2|Bacteria,1RGZZ@1224|Proteobacteria,2VSZ6@28216|Betaproteobacteria,4773W@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	prepilin-type N-terminal cleavage methylation	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
EH2_k127_5192228_2	1163617.SCD_n00063	1.429e-12	73.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
EH2_k127_5192228_1	1123392.AQWL01000004_gene2561	2.981e-117	385.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,1KSQZ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5192228_0	292415.Tbd_2130	2.286e-125	411.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,1KRJI@119069|Hydrogenophilales	119069|Hydrogenophilales	L	NUDIX domain	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
EH2_k127_5245850_0	396588.Tgr7_0871	1.119e-204	647.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1WXDW@135613|Chromatiales	135613|Chromatiales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
EH2_k127_5245850_1	1123393.KB891316_gene1451	3.849e-91	312.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,1KRY9@119069|Hydrogenophilales	119069|Hydrogenophilales	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
EH2_k127_5245850_2	583345.Mmol_0828	8.017e-13	68.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,2KM8E@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
EH2_k127_5246218_1	1163617.SCD_n01981	4.643e-109	363.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
EH2_k127_5246218_4	1123392.AQWL01000001_gene1455	1.938e-62	224.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,1KSUU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
EH2_k127_5246218_3	292415.Tbd_2020	2.245e-85	289.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
EH2_k127_5246218_2	1123257.AUFV01000005_gene1439	1.754e-104	344.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
EH2_k127_5246218_0	1163617.SCD_n01987	6.287e-119	402.0	COG4398@1|root,COG4398@2|Bacteria,1RBRR@1224|Proteobacteria,2VQ7K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
EH2_k127_5246218_5	323848.Nmul_A2703	3.533e-39	150.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,37352@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
EH2_k127_5265135_0	1163617.SCD_n00563	2.201e-183	589.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
EH2_k127_5296826_1	292415.Tbd_2164	1.772e-148	473.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,1KRA2@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
EH2_k127_5296826_2	748247.AZKH_3667	2.948e-53	191.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,2KWM2@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_5296826_3	69395.JQLZ01000001_gene3230	6.835e-43	165.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH2_k127_5296826_0	1123393.KB891316_gene1462	2.787e-160	512.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,1KREZ@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
EH2_k127_5317122_2	1071679.BG57_10360	1.339e-62	234.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
EH2_k127_5317122_0	765910.MARPU_12065	2.963e-89	303.0	COG1752@1|root,COG1752@2|Bacteria,1R4TX@1224|Proteobacteria,1RP66@1236|Gammaproteobacteria,1X0EE@135613|Chromatiales	135613|Chromatiales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
EH2_k127_5317122_1	1123393.KB891333_gene2517	1.03e-71	247.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,1KS4G@119069|Hydrogenophilales	119069|Hydrogenophilales	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
EH2_k127_5323799_2	375286.mma_1170	9.502e-28	116.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,475J4@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	tar3	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,TarH
EH2_k127_5323799_0	572477.Alvin_2236	4.25e-102	339.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WXKT@135613|Chromatiales	135613|Chromatiales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
EH2_k127_5323799_1	395494.Galf_1025	1.028e-87	295.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,44W6N@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	CheD chemotactic sensory transduction	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
EH2_k127_5323799_3	1123393.KB891333_gene2675	2.924e-13	69.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,1KSF1@119069|Hydrogenophilales	119069|Hydrogenophilales	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_5329142_0	1399147.P618_200404	1.53e-145	471.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,47F3E@766|Rickettsiales	766|Rickettsiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
EH2_k127_5329142_2	502025.Hoch_5071	9.115e-54	192.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
EH2_k127_5329142_1	177439.DP2938	1.479e-121	399.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2MJ69@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_5345190_5	1379698.RBG1_1C00001G1379	1.665e-05	57.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GON,PQQ_2,Peptidase_S8,SBBP,VCBS
EH2_k127_5345190_1	471854.Dfer_0264	1.312e-27	127.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
EH2_k127_5345190_0	1349767.GJA_94	7.753e-76	268.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria,477P6@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
EH2_k127_5345190_2	1163617.SCD_n01880	3.413e-26	110.0	2E5B5@1|root,33039@2|Bacteria,1NDK8@1224|Proteobacteria,2W5JF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5345190_4	1123392.AQWL01000001_gene1608	6.164e-11	65.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,1KTER@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5345190_3	580332.Slit_2634	4.29e-13	77.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,2WHEY@28216|Betaproteobacteria,44V0X@713636|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
EH2_k127_5349717_3	1123393.KB891317_gene2205	8.746e-07	52.0	2CB73@1|root,32RST@2|Bacteria,1MZWF@1224|Proteobacteria,2VV2C@28216|Betaproteobacteria,1KSSX@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5349717_1	316055.RPE_1227	2.61e-40	155.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,2U9I3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
EH2_k127_5349717_0	1123393.KB891317_gene2207	3.035e-102	339.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
EH2_k127_5387649_5	1163617.SCD_n01778	9.419e-20	89.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
EH2_k127_5387649_2	1266925.JHVX01000010_gene1332	2.014e-81	280.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2VMWZ@28216|Betaproteobacteria,372M9@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_5387649_4	748247.AZKH_2443	7.893e-52	186.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,2KZ5E@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the DsbB family	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
EH2_k127_5387649_3	338969.Rfer_0414	7.612e-72	257.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
EH2_k127_5387649_1	1123392.AQWL01000004_gene2670	1.428e-136	439.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1KREJ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
EH2_k127_5387649_0	1304883.KI912532_gene2616	5.8e-204	644.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,2KUWJ@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
EH2_k127_5432532_1	1123393.KB891327_gene292	1.013e-96	323.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,1KS25@119069|Hydrogenophilales	119069|Hydrogenophilales	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
EH2_k127_5432532_2	497321.C664_16455	2.437e-84	295.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUPC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,MCPsignal,PAS_3
EH2_k127_5432532_0	395494.Galf_2780	9.807e-138	452.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,44WBX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
EH2_k127_5439838_3	338969.Rfer_3634	1.053e-15	79.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
EH2_k127_5439838_0	1163617.SCD_n01156	6.429e-257	802.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
EH2_k127_5439838_2	1163617.SCD_n01157	1.024e-69	241.0	COG3439@1|root,COG3439@2|Bacteria,1N4Z5@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_5439838_1	1123392.AQWL01000001_gene1648	3.144e-171	542.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,1KRJ1@119069|Hydrogenophilales	119069|Hydrogenophilales	L	KaiC	-	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
EH2_k127_5450911_2	1123393.KB891328_gene622	1.95e-32	131.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,1KRPM@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
EH2_k127_5450911_1	640081.Dsui_3536	2.822e-223	702.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KU6P@206389|Rhodocyclales	206389|Rhodocyclales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
EH2_k127_5450911_0	76114.ebA5461	2.007e-238	746.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,2KUYZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_5450911_3	62928.azo1630	8.232e-09	58.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,2KUG9@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_5456983_1	292415.Tbd_1520	4.112e-140	453.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,1KRDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
EH2_k127_5456983_2	1163617.SCD_n01908	2.947e-130	429.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
EH2_k127_5456983_7	1304883.KI912532_gene491	4.604e-18	91.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
EH2_k127_5456983_6	292415.Tbd_1829	2.366e-42	159.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
EH2_k127_5456983_4	323848.Nmul_A1002	1.3e-104	342.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,372NI@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
EH2_k127_5456983_3	292415.Tbd_1831	1.778e-106	350.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1KRJ9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C1 family	-	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
EH2_k127_5456983_0	292415.Tbd_1832	5.28e-230	715.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
EH2_k127_5456983_5	1163617.SCD_n00601	4.698e-97	322.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
EH2_k127_5470227_0	1123392.AQWL01000002_gene1763	8.636e-160	506.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,1KT2B@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_5470227_2	1163617.SCD_n00156	5.437e-103	344.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
EH2_k127_5470227_1	1123392.AQWL01000002_gene2036	7.491e-127	422.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,1KRFG@119069|Hydrogenophilales	119069|Hydrogenophilales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
EH2_k127_5470227_3	1123393.KB891330_gene824	9.175e-70	244.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,1KRS6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
EH2_k127_5470227_4	269482.Bcep1808_2991	1.76e-10	61.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,1K7RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
EH2_k127_5471447_2	159087.Daro_3883	5.589e-161	510.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
EH2_k127_5471447_3	342113.DM82_2518	7.008e-85	287.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
EH2_k127_5471447_4	1000565.METUNv1_02974	1.83e-78	274.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,2KUUS@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
EH2_k127_5471447_6	1123393.KB891316_gene1757	1.658e-45	180.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,1KRVR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
EH2_k127_5471447_8	380394.Lferr_0437	7.348e-13	79.0	COG1872@1|root,COG1872@2|Bacteria,1NGWG@1224|Proteobacteria,1SY5J@1236|Gammaproteobacteria,2NDAJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
EH2_k127_5471447_1	1123393.KB891316_gene1755	2.007e-184	598.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2W1AV@28216|Betaproteobacteria,1KS9Y@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
EH2_k127_5471447_0	292415.Tbd_2437	3.129e-228	716.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,1KSFE@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
EH2_k127_5471447_5	1485544.JQKP01000001_gene923	6.261e-56	201.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,44VR4@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH2_k127_5471447_7	1121004.ATVC01000063_gene1631	9.392e-18	83.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KR0M@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
EH2_k127_5475120_3	1123393.KB891317_gene2279	1.932e-47	171.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,1KRM8@119069|Hydrogenophilales	119069|Hydrogenophilales	V	Ami_2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
EH2_k127_5475120_1	265072.Mfla_0594	4.6e-52	187.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,2KMU9@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
EH2_k127_5475120_0	1485544.JQKP01000019_gene30	2.163e-105	355.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,44V75@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
EH2_k127_5475120_2	1123392.AQWL01000001_gene1417	3.96e-49	178.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,1KS9G@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
EH2_k127_5475628_3	159087.Daro_2958	2.108e-117	383.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KVF1@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
EH2_k127_5475628_5	1120963.KB894491_gene1107	7.035e-09	57.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5475628_2	1123367.C666_17020	9.719e-134	438.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KU9B@206389|Rhodocyclales	206389|Rhodocyclales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
EH2_k127_5475628_4	292415.Tbd_1677	8.579e-107	349.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KRDV@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
EH2_k127_5475628_1	1123392.AQWL01000008_gene1181	3.627e-212	664.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KRGT@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
EH2_k127_5475628_0	1349767.GJA_2392	0.0	1218.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,473C8@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
EH2_k127_5475628_6	981223.AIED01000149_gene464	2.742e-07	54.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5476663_2	1123393.KB891317_gene2469	1.284e-91	302.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria,1KSGV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,FlpD,Pyr_redox_2
EH2_k127_5476663_1	1123393.KB891317_gene2470	6.443e-97	321.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria,1KSVN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
EH2_k127_5476663_0	292415.Tbd_1645	1.16e-165	526.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
EH2_k127_5476663_3	1163617.SCD_n01880	7.406e-26	111.0	2E5B5@1|root,33039@2|Bacteria,1NDK8@1224|Proteobacteria,2W5JF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5476663_5	323848.Nmul_A1813	4.101e-11	66.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,373QW@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
EH2_k127_5476663_4	748247.AZKH_3926	8.146e-15	81.0	COG4191@1|root,COG4191@2|Bacteria,1QU7R@1224|Proteobacteria,2VICU@28216|Betaproteobacteria,2KUXS@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction histidine kinase	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
EH2_k127_547704_2	748247.AZKH_3437	5.309e-24	102.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,2KW1K@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_547704_1	1071679.BG57_20650	2.831e-86	304.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1K16K@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH2_k127_547704_0	1123392.AQWL01000002_gene1833	2.571e-129	420.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1KRG4@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
EH2_k127_549125_1	1121403.AUCV01000016_gene4409	6.117e-68	245.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MHR5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
EH2_k127_549125_0	1123392.AQWL01000006_gene636	7.308e-305	948.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_549125_2	626887.J057_09326	1.158e-14	77.0	2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,466D3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0500 SAM-dependent methyltransferases	PP0279	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
EH2_k127_5498269_2	1123393.KB891317_gene2490	1.215e-57	204.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,1KRRZ@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
EH2_k127_5498269_1	580332.Slit_0569	2.592e-87	295.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,2VISC@28216|Betaproteobacteria,44V95@713636|Nitrosomonadales	28216|Betaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_5498269_0	1123354.AUDR01000016_gene1285	3.237e-114	373.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,1KRI2@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_5498269_4	159087.Daro_0755	4.054e-36	145.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2VRIC@28216|Betaproteobacteria,2KWEC@206389|Rhodocyclales	206389|Rhodocyclales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
EH2_k127_5498269_3	640081.Dsui_1739	3.201e-52	188.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,2KV45@206389|Rhodocyclales	206389|Rhodocyclales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
EH2_k127_5499922_2	1121438.JNJA01000007_gene1645	3.979e-79	269.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
EH2_k127_5499922_3	1121441.AUCX01000017_gene1960	9.881e-56	206.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,43DEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
EH2_k127_5499922_1	1163617.SCD_n02207	5.656e-116	382.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
EH2_k127_5499922_0	76114.ebA1417	1.172e-192	610.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
EH2_k127_5540762_3	1165096.ARWF01000001_gene350	7.7e-19	87.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales	206350|Nitrosomonadales	CI	TIGRFAM oxaloacetate decarboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
EH2_k127_5540762_2	1123392.AQWL01000007_gene908	1.617e-78	267.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KSDR@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
EH2_k127_5540762_1	159087.Daro_2010	8.769e-85	293.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,2KW5K@206389|Rhodocyclales	206389|Rhodocyclales	H	Uroporphyrin-III C tetrapyrrole	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
EH2_k127_5540762_0	640081.Dsui_2466	3.094e-108	354.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase	dnaL	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
EH2_k127_5550764_0	269799.Gmet_2767	0.0	1207.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42Y60@68525|delta/epsilon subdivisions,2WUR1@28221|Deltaproteobacteria,43T95@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
EH2_k127_5550764_1	595494.Tola_1291	8.485e-65	227.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,1S5WC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5550764_2	864051.BurJ1DRAFT_3400	8.567e-23	99.0	COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,2VR22@28216|Betaproteobacteria,1KM3V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
EH2_k127_555282_3	1163617.SCD_n01219	2.607e-59	208.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
EH2_k127_555282_0	1163617.SCD_n01218	4.162e-138	450.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_555282_5	1163617.SCD_n02383	5.759e-47	174.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH2_k127_555282_1	398767.Glov_0812	6.52e-129	417.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
EH2_k127_555282_4	1163617.SCD_n01732	1.01e-53	197.0	28JUM@1|root,2Z9JN@2|Bacteria,1NDV6@1224|Proteobacteria,2VJ3P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_555282_2	1123392.AQWL01000009_gene1115	2.43e-116	376.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PUA-like domain	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PK,PUA_2
EH2_k127_555683_2	1163617.SCD_n01388	9.641e-05	49.0	COG0694@1|root,COG0694@2|Bacteria,1NHWB@1224|Proteobacteria,2VXQB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
EH2_k127_555683_1	1123393.KB891331_gene2987	2.108e-72	253.0	COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,2VQ55@28216|Betaproteobacteria,1KSU2@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
EH2_k127_555683_0	1123393.KB891316_gene1088	2.122e-210	657.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,1KRD7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
EH2_k127_5566464_1	1123393.KB891332_gene2784	9.21e-61	212.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,2VPN4@28216|Betaproteobacteria,1KSBJ@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
EH2_k127_5566464_0	857087.Metme_3258	1.549e-290	912.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
EH2_k127_5568341_4	1538295.JY96_00965	1.165e-26	114.0	COG4390@1|root,COG4390@2|Bacteria,1N8RK@1224|Proteobacteria,2VUJW@28216|Betaproteobacteria,1KMFT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2322)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2322
EH2_k127_5568341_1	582744.Msip34_0438	5.394e-84	283.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KMJS@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
EH2_k127_5568341_0	861299.J421_5885	3.234e-146	498.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1ZUID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
EH2_k127_5568341_3	205918.Psyr_4494	2.452e-47	181.0	COG3221@1|root,COG3221@2|Bacteria,1QHD7@1224|Proteobacteria,1TF0Z@1236|Gammaproteobacteria,1Z9KD@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_5568341_2	1123401.JHYQ01000014_gene862	2.298e-69	243.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
EH2_k127_5577450_1	1123392.AQWL01000001_gene1436	1.756e-146	475.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
EH2_k127_5577450_5	1123392.AQWL01000001_gene1437	3.193e-18	88.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C
EH2_k127_5577450_0	292415.Tbd_2033	2.288e-153	492.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,1KRDW@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Ferrochelatase	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
EH2_k127_5577450_4	1192124.LIG30_1324	8.021e-109	359.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,2VKMS@28216|Betaproteobacteria,1KHH0@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dyp-type peroxidase family	dyp	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
EH2_k127_5577450_2	1123392.AQWL01000001_gene1439	2.209e-139	451.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,1KRX4@119069|Hydrogenophilales	119069|Hydrogenophilales	K	HrcA protein C terminal domain	-	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
EH2_k127_5577450_3	1163617.SCD_n00909	9.448e-115	376.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
EH2_k127_559381_4	292415.Tbd_1538	1.948e-141	454.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,1KSEA@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp70 protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
EH2_k127_559381_0	1123393.KB891333_gene2566	1.165e-186	588.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KRI6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
EH2_k127_559381_2	1123393.KB891316_gene1080	2.884e-173	556.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria,1KSZT@119069|Hydrogenophilales	119069|Hydrogenophilales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
EH2_k127_559381_5	1430440.MGMSRv2_2159	1.978e-71	249.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,2JSZA@204441|Rhodospirillales	204441|Rhodospirillales	K	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
EH2_k127_559381_1	640081.Dsui_3159	9.467e-180	587.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUUR@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
EH2_k127_559381_3	1121035.AUCH01000019_gene2868	3.971e-168	535.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
EH2_k127_559381_6	338969.Rfer_4174	1.647e-26	112.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2VQMP@28216|Betaproteobacteria,4AGAN@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	dctQ	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
EH2_k127_5607580_2	228410.NE1871	2.945e-53	191.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2VHYC@28216|Betaproteobacteria,371MW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
EH2_k127_5607580_1	1288494.EBAPG3_22580	2.989e-158	507.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,372GN@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
EH2_k127_5607580_0	1123393.KB891331_gene2855	8.381e-220	688.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,1KRE6@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
EH2_k127_5624441_0	1123393.KB891328_gene592	2.888e-147	473.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,1KS6P@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_5624441_3	159087.Daro_3710	2.333e-09	66.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,2KXFN@206389|Rhodocyclales	206389|Rhodocyclales	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH2_k127_5624441_2	1163617.SCD_n02507	1.421e-38	156.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
EH2_k127_5624441_1	265072.Mfla_2081	3.28e-77	269.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,2KMHI@206350|Nitrosomonadales	206350|Nitrosomonadales	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
EH2_k127_5624441_5	1266908.AQPB01000060_gene237	3.519e-07	59.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1WYU2@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
EH2_k127_5624441_4	228410.NE1746	4.847e-09	57.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VW3E@28216|Betaproteobacteria,3736T@32003|Nitrosomonadales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
EH2_k127_5627872_1	1123393.KB891327_gene362	4.508e-58	205.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,1KSTH@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
EH2_k127_5627872_0	159087.Daro_0940	2.039e-75	255.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KUSV@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
EH2_k127_5627872_3	1163617.SCD_n00921	2.344e-52	188.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
EH2_k127_5627872_4	243365.CV_3799	2.472e-31	126.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,2KRJV@206351|Neisseriales	206351|Neisseriales	J	RNA-binding protein, YhbY family	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
EH2_k127_5627872_2	640081.Dsui_3060	6.132e-55	198.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
EH2_k127_5633073_3	1112274.KI911560_gene460	3.02e-61	214.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,2KM0T@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
EH2_k127_5633073_0	1123392.AQWL01000003_gene175	0.0	1166.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
EH2_k127_5633073_4	1163617.SCD_n00983	4.507e-61	221.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
EH2_k127_5633073_2	1163617.SCD_n00492	4.812e-139	451.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
EH2_k127_5633073_1	640081.Dsui_2420	7.908e-267	850.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
EH2_k127_5641213_0	1163617.SCD_n01153	3.921e-201	632.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
EH2_k127_5641213_1	1163617.SCD_n01152	1.961e-54	195.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
EH2_k127_5672396_3	1123392.AQWL01000005_gene3217	2.223e-122	401.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KRQV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,GATase_3
EH2_k127_5672396_1	1163617.SCD_n02707	2.381e-145	470.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
EH2_k127_5672396_4	1163617.SCD_n02708	1.222e-110	362.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
EH2_k127_5672396_5	1123393.KB891316_gene1842	8.297e-34	140.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria,1KRYR@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5672396_0	292415.Tbd_2477	0.0	1051.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
EH2_k127_5672396_2	1123393.KB891316_gene1844	1.304e-122	395.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,2VNTI@28216|Betaproteobacteria,1KSW5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
EH2_k127_5674461_0	305700.B447_05588	0.0	1385.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
EH2_k127_5674461_2	1123392.AQWL01000007_gene887	1.433e-130	431.0	COG0664@1|root,COG1295@1|root,COG0664@2|Bacteria,COG1295@2|Bacteria,1PWBZ@1224|Proteobacteria,2VY5Z@28216|Betaproteobacteria,1KSQT@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB,cNMP_binding
EH2_k127_5674461_1	1163617.SCD_n01692	1.01e-201	635.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
EH2_k127_5676510_5	640081.Dsui_3215	1.862e-91	316.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria,2KW03@206389|Rhodocyclales	206389|Rhodocyclales	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
EH2_k127_5676510_0	159087.Daro_2851	9.617e-240	749.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KUBN@206389|Rhodocyclales	206389|Rhodocyclales	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH2_k127_5676510_1	1163617.SCD_n02204	4.72e-222	696.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
EH2_k127_5676510_4	305700.B447_03423	1.527e-101	349.0	COG0515@1|root,COG1639@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,2KUM0@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HDOD,Pkinase
EH2_k127_5676510_6	1123392.AQWL01000004_gene2782	8.97e-86	287.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,1KRNR@119069|Hydrogenophilales	119069|Hydrogenophilales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
EH2_k127_5676510_7	292415.Tbd_0516	6.601e-47	170.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KRPW@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
EH2_k127_5676510_2	580332.Slit_1265	5.439e-172	557.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,44V5X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
EH2_k127_5676510_3	292415.Tbd_0514	1.774e-107	351.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1KRZJ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
EH2_k127_5682281_2	1163617.SCD_n00013	4.928e-120	397.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
EH2_k127_5682281_3	323848.Nmul_A0389	3.856e-106	358.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,3721F@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
EH2_k127_5682281_0	1123392.AQWL01000002_gene1711	5.475e-195	618.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
EH2_k127_5682281_1	292415.Tbd_0022	2.399e-125	409.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KSYA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH2_k127_5684279_0	1123367.C666_12475	1.54e-156	499.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,2KVM3@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
EH2_k127_5684279_2	62928.azo3124	8.073e-82	281.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,2KVYQ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
EH2_k127_5684279_4	292415.Tbd_2664	6.124e-32	140.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria	1224|Proteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
EH2_k127_5684279_1	1123392.AQWL01000006_gene602	1.995e-145	479.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KRAF@119069|Hydrogenophilales	119069|Hydrogenophilales	F	ATP-grasp domain	-	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
EH2_k127_5684279_3	292415.Tbd_2661	5.871e-67	231.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,1KRNW@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
EH2_k127_5698102_0	1255043.TVNIR_1329	0.0	1093.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WW7D@135613|Chromatiales	135613|Chromatiales	C	Molybdopterin oxidoreductase Fe4S4 domain	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_5698102_3	713587.THITH_07520	4.419e-19	91.0	COG3062@1|root,COG3062@2|Bacteria,1PUNN@1224|Proteobacteria,1TKDR@1236|Gammaproteobacteria,1X21U@135613|Chromatiales	135613|Chromatiales	P	NapD protein	-	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
EH2_k127_5698102_2	1163617.SCD_n00378	1.104e-52	194.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_5698102_1	292415.Tbd_1907	7.362e-206	645.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KRAP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
EH2_k127_5706238_2	580332.Slit_2419	1.196e-142	457.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,44W8A@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
EH2_k127_5706238_0	266264.Rmet_1541	2.15e-225	711.0	COG0223@1|root,COG1024@1|root,COG0223@2|Bacteria,COG1024@2|Bacteria,1MWYJ@1224|Proteobacteria,2VK38@28216|Betaproteobacteria,1KBJJ@119060|Burkholderiaceae	28216|Betaproteobacteria	IJ	Formyl transferase	hoxX	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
EH2_k127_5706238_1	1163617.SCD_n01574	9.199e-190	601.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
EH2_k127_5706238_3	522306.CAP2UW1_2347	1.087e-15	84.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
EH2_k127_574469_3	1175306.GWL_15080	1.002e-68	235.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,4743H@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Redoxin	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_574469_0	1123392.AQWL01000008_gene1216	5.964e-243	759.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,1KRG1@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Large family of predicted nucleotide-binding domains	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
EH2_k127_574469_4	1123392.AQWL01000009_gene1065	1.467e-60	233.0	COG0760@1|root,COG0760@2|Bacteria,1R4EF@1224|Proteobacteria,2VK6Z@28216|Betaproteobacteria,1KT06@119069|Hydrogenophilales	119069|Hydrogenophilales	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
EH2_k127_574469_2	1123392.AQWL01000002_gene1962	9.108e-120	392.0	COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,2WGG8@28216|Betaproteobacteria,1KSXE@119069|Hydrogenophilales	119069|Hydrogenophilales	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_574469_1	1123393.KB891331_gene2858	8.911e-130	431.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,2VR9V@28216|Betaproteobacteria,1KSRS@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Adenylylsulphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
EH2_k127_5782387_6	1192124.LIG30_2112	5.474e-09	66.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,1K04E@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
EH2_k127_5782387_3	864073.HFRIS_008391	3.865e-63	225.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,4748U@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
EH2_k127_5782387_5	1485544.JQKP01000007_gene1958	4.704e-37	150.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,44VS3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
EH2_k127_5782387_1	1123392.AQWL01000005_gene3080	4.63e-87	302.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,1KRN7@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
EH2_k127_5782387_2	1123393.KB891316_gene1669	4.164e-76	265.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,1KSBP@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
EH2_k127_5782387_4	435908.IDSA_11220	9.757e-44	175.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RZBU@1236|Gammaproteobacteria,2QGAW@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH2_k127_5782387_0	1159870.KB907784_gene515	1.532e-257	810.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,3T227@506|Alcaligenaceae	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
EH2_k127_5783104_0	1123392.AQWL01000013_gene2404	0.0	1088.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,1KRA6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
EH2_k127_5783104_2	1123393.KB891316_gene2076	1.755e-68	247.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,1KSYX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
EH2_k127_5783104_1	1123392.AQWL01000006_gene583	4.21e-125	406.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,1KST9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
EH2_k127_5783104_4	1101195.Meth11DRAFT_2247	6.113e-13	76.0	COG3767@1|root,COG3767@2|Bacteria,1PW8F@1224|Proteobacteria,2WBTI@28216|Betaproteobacteria,2KN9B@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5783104_3	76114.ebA4332	7.768e-46	169.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,2KWPP@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
EH2_k127_5799010_2	768671.ThimaDRAFT_3834	2.709e-08	57.0	2C2BS@1|root,33MU0@2|Bacteria,1NK7Y@1224|Proteobacteria,1SHTK@1236|Gammaproteobacteria,1WZJY@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5799010_0	572477.Alvin_0839	0.0	1087.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
EH2_k127_5799010_1	1095769.CAHF01000022_gene96	1.08e-55	201.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM EAL domain, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
EH2_k127_5803837_6	1123393.KB891317_gene2332	2.622e-82	281.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria,1KRXZ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH2_k127_5803837_4	1123393.KB891317_gene2331	1.898e-119	404.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,1KRIA@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70 factor, region 1.2	-	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_5803837_8	946483.Cenrod_1481	5.641e-59	216.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,4A9WP@80864|Comamonadaceae	28216|Betaproteobacteria	DM	peptidase	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
EH2_k127_5803837_7	580332.Slit_0325	4.361e-63	230.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
EH2_k127_5803837_5	1123393.KB891317_gene2328	6.407e-106	350.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,1KRF6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
EH2_k127_5803837_3	1123368.AUIS01000019_gene1205	1.168e-137	445.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
EH2_k127_5803837_2	153948.NAL212_1571	8.558e-150	488.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2VNUH@28216|Betaproteobacteria,373XH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
EH2_k127_5803837_10	760117.JN27_05300	1.019e-45	168.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,474HH@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
EH2_k127_5803837_9	1266925.JHVX01000003_gene628	8.636e-47	170.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,373C7@32003|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
EH2_k127_5803837_0	1121035.AUCH01000004_gene289	3.677e-259	819.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KUJG@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
EH2_k127_5803837_1	1123393.KB891327_gene257	8.093e-169	533.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,1KRBG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class II core domain (F)	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
EH2_k127_5812085_0	1304883.KI912532_gene1993	1.645e-120	397.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,2KUIM@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	HlyD_D23
EH2_k127_5812085_1	1123392.AQWL01000008_gene1184	1.312e-99	332.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,1KS6Z@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
EH2_k127_583067_0	292415.Tbd_0270	5.249e-130	420.0	COG0547@1|root,COG0547@2|Bacteria,1PWC3@1224|Proteobacteria,2WBX0@28216|Betaproteobacteria,1KSR4@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycosyl transferase family, helical bundle domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N
EH2_k127_583067_1	396588.Tgr7_3147	1.95e-51	185.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,1S98H@1236|Gammaproteobacteria,1X18F@135613|Chromatiales	135613|Chromatiales	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
EH2_k127_583067_2	1049564.TevJSym_be00230	1.275e-26	113.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1SCFP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_5840055_0	795666.MW7_1298	0.0	1077.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K16W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
EH2_k127_5867396_5	1485544.JQKP01000009_gene857	1.892e-11	72.0	COG0457@1|root,COG5337@1|root,COG0457@2|Bacteria,COG5337@2|Bacteria,1NBQU@1224|Proteobacteria,2WG3E@28216|Betaproteobacteria	1224|Proteobacteria	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
EH2_k127_5867396_1	1158756.AQXQ01000012_gene1565	1.907e-140	463.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3
EH2_k127_5867396_3	765911.Thivi_0315	1.219e-76	261.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,1SBPR@1236|Gammaproteobacteria,1WY4R@135613|Chromatiales	135613|Chromatiales	NT	CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
EH2_k127_5867396_4	572477.Alvin_2461	5.686e-49	177.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	EAL,LytTR,Response_reg
EH2_k127_5867396_2	402626.Rpic_2716	2.022e-105	350.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,1K2JS@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
EH2_k127_5867396_0	62928.azo1566	1.134e-198	624.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
EH2_k127_5870718_0	1123392.AQWL01000003_gene399	1.591e-99	325.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KSBR@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
EH2_k127_5870718_2	1123257.AUFV01000015_gene3552	1.536e-69	252.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,1X9M9@135614|Xanthomonadales	135614|Xanthomonadales	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH2_k127_5870718_5	1056820.KB900648_gene3024	6.931e-19	94.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,2PPWP@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH2_k127_5870718_6	1121033.AUCF01000011_gene1796	1.579e-16	82.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,2TV7C@28211|Alphaproteobacteria,2JV2C@204441|Rhodospirillales	204441|Rhodospirillales	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH2_k127_5870718_3	1337936.IJ00_27170	4.391e-29	117.0	COG0469@1|root,COG0469@2|Bacteria,1G2QX@1117|Cyanobacteria,1HM7D@1161|Nostocales	1117|Cyanobacteria	G	PFAM Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
EH2_k127_5870718_7	1157708.KB907452_gene3974	1.913e-11	69.0	2EC4W@1|root,3363P@2|Bacteria,1N7E3@1224|Proteobacteria,2VWC7@28216|Betaproteobacteria,4AFB8@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5870718_4	1304883.KI912532_gene1531	6.787e-27	115.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,2KURY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
EH2_k127_5870718_1	1304883.KI912532_gene1531	6.048e-80	280.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,2KURY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
EH2_k127_59002_1	640511.BC1002_5277	1.003e-49	183.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,1K70P@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
EH2_k127_59002_0	1121035.AUCH01000005_gene60	9.249e-164	533.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales	206389|Rhodocyclales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
EH2_k127_5905045_1	1163617.SCD_n02665	9.93e-85	287.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_5905045_0	62928.azo2817	2.007e-143	462.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,2KUW8@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
EH2_k127_5905045_3	1123393.KB891330_gene780	9.272e-39	150.0	2DPBX@1|root,331FU@2|Bacteria,1NB0X@1224|Proteobacteria,2VX47@28216|Betaproteobacteria,1KSRG@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_5905045_2	1288494.EBAPG3_21760	1.7e-52	191.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,3732H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
EH2_k127_5921988_2	1000565.METUNv1_01597	3.417e-42	158.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,2KUNW@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
EH2_k127_5921988_1	713587.THITH_16195	3.292e-68	236.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1WWDJ@135613|Chromatiales	135613|Chromatiales	CO	TIGRFAM periplasmic protein	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
EH2_k127_5921988_3	1288494.EBAPG3_12750	1.254e-38	154.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,37311@32003|Nitrosomonadales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
EH2_k127_5921988_0	1255043.TVNIR_0264	3.602e-88	306.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_19,TPR_2
EH2_k127_5931924_3	1163617.SCD_n02845	2.738e-46	167.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
EH2_k127_5931924_1	1123393.KB891331_gene2909	7.293e-215	672.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1KS7D@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoglycerate kinase	-	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
EH2_k127_5931924_0	292415.Tbd_0162	1.543e-242	762.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1KRXV@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Pyruvate kinase, alpha/beta domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
EH2_k127_5931924_2	1123392.AQWL01000002_gene1912	3.091e-185	580.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KRDZ@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
EH2_k127_5947507_2	1485544.JQKP01000012_gene2110	4.986e-66	227.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,44V19@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
EH2_k127_5947507_0	1123392.AQWL01000001_gene1354	2.194e-236	739.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
EH2_k127_5947507_1	1123393.KB891316_gene1431	8.315e-126	410.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2WH34@28216|Betaproteobacteria,1KSTU@119069|Hydrogenophilales	119069|Hydrogenophilales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	6PGD,NAD_binding_2
EH2_k127_5947507_3	1485544.JQKP01000007_gene1966	3.71e-25	111.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,44V0E@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
EH2_k127_596852_2	1485544.JQKP01000002_gene1623	1.645e-114	373.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
EH2_k127_596852_3	1095769.CAHF01000014_gene2905	1.184e-30	131.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,4731B@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
EH2_k127_596852_0	1163617.SCD_n02480	6.661e-200	629.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
EH2_k127_596852_1	1298593.TOL_0807	1.53e-132	433.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XIF2@135619|Oceanospirillales	135619|Oceanospirillales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
EH2_k127_596852_4	666681.M301_2415	1.977e-25	108.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KKCT@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
EH2_k127_601786_2	224911.27350827	0.0006651	42.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_601786_1	292415.Tbd_0863	7.381e-133	431.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,1KRCU@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
EH2_k127_601786_0	1123393.KB891317_gene2194	1.827e-141	458.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,1KSQR@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
EH2_k127_6023903_2	1286631.X805_19810	4.162e-42	159.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,1KKV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
EH2_k127_6023903_0	580332.Slit_0657	5.815e-116	383.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,44VFP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
EH2_k127_6023903_1	472759.Nhal_2449	1.229e-43	165.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1WY89@135613|Chromatiales	135613|Chromatiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
EH2_k127_6023903_3	1123393.KB891316_gene1506	1.378e-38	147.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,1KS4X@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
EH2_k127_602422_5	1288494.EBAPG3_29950	2.169e-75	256.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,372YI@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
EH2_k127_602422_11	522306.CAP2UW1_3477	1.726e-46	169.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,1KQ25@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
EH2_k127_602422_4	1123393.KB891318_gene2151	1.233e-81	274.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,1KRKS@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
EH2_k127_602422_13	1454004.AW11_00702	5.015e-21	93.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,1KQ4Y@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
EH2_k127_602422_7	580332.Slit_0786	2.488e-55	199.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
EH2_k127_602422_0	292415.Tbd_0425	1.757e-241	751.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,1KRD8@119069|Hydrogenophilales	119069|Hydrogenophilales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
EH2_k127_602422_12	626418.bglu_1g02790	1.295e-36	149.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,1K9AT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
EH2_k127_602422_14	1286106.MPL1_09717	1.103e-12	68.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,461DS@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
EH2_k127_602422_9	323848.Nmul_A0789	2.264e-53	189.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,37389@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
EH2_k127_602422_6	292415.Tbd_0428	3.269e-71	241.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,1KRMC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
EH2_k127_602422_2	1288494.EBAPG3_30050	2.099e-104	344.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,371ZR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
EH2_k127_602422_1	323848.Nmul_A0792	2.971e-154	492.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,372HG@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
EH2_k127_602422_8	1051985.l11_00530	1.838e-53	190.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,2KR2K@206351|Neisseriales	206351|Neisseriales	J	ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
EH2_k127_602422_3	292415.Tbd_0432	1.788e-92	310.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2VQJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
EH2_k127_602422_10	1120956.JHZK01000015_gene2978	1.407e-50	186.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria,1JN1K@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	MOFRL family	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
EH2_k127_6033913_4	56780.SYN_01331	4.679e-65	223.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MQYI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Phosphorylase
EH2_k127_6033913_2	1123392.AQWL01000001_gene1594	7.731e-91	302.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,1KRKK@119069|Hydrogenophilales	119069|Hydrogenophilales	A	EXOIII	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
EH2_k127_6033913_0	243365.CV_2367	9.682e-140	456.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,2KQA1@206351|Neisseriales	206351|Neisseriales	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
EH2_k127_6033913_7	1123392.AQWL01000001_gene1593	1.139e-24	113.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VWE5@28216|Betaproteobacteria,1KT8P@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6033913_6	335283.Neut_2288	1.983e-40	153.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,2WFUX@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
EH2_k127_6033913_3	1163617.SCD_n01940	7.83e-90	307.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
EH2_k127_6033913_1	153948.NAL212_0293	4.648e-117	389.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,3722T@32003|Nitrosomonadales	28216|Betaproteobacteria	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
EH2_k127_6033913_5	1123392.AQWL01000001_gene1590	4.311e-58	205.0	COG1416@1|root,COG1416@2|Bacteria,1RHW0@1224|Proteobacteria,2VWXN@28216|Betaproteobacteria,1KSFB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
EH2_k127_6037548_1	1049564.TevJSym_af00530	3.092e-44	170.0	28K74@1|root,2Z9VA@2|Bacteria,1R8MQ@1224|Proteobacteria,1SKKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6037548_0	1123392.AQWL01000004_gene2618	9.102e-267	832.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJJV@28216|Betaproteobacteria,1KSRR@119069|Hydrogenophilales	119069|Hydrogenophilales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH2_k127_6041620_1	395494.Galf_0420	1.943e-125	413.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria,44UZA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M17 leucyl aminopeptidase domain protein	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
EH2_k127_6041620_0	265072.Mfla_2074	1.609e-241	754.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KKET@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
EH2_k127_6044152_3	1121035.AUCH01000015_gene2581	1.816e-06	53.0	2EA8Z@1|root,334DE@2|Bacteria,1NDKW@1224|Proteobacteria,2VVWJ@28216|Betaproteobacteria,2KXKV@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6044152_0	1163617.SCD_n01964	5.129e-214	674.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH2_k127_6044152_1	1485544.JQKP01000003_gene94	1.015e-209	662.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,44VB5@713636|Nitrosomonadales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_6044152_2	66692.ABC1024	1.587e-10	63.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
EH2_k127_6058361_1	1123393.KB891316_gene1584	3.522e-17	83.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria,2VWBE@28216|Betaproteobacteria,1KT1N@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
EH2_k127_6058361_0	1163617.SCD_n02537	1.416e-149	482.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
EH2_k127_6065099_2	748247.AZKH_4246	6.818e-59	210.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
EH2_k127_6065099_3	159087.Daro_0355	3.082e-58	204.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,2KWF2@206389|Rhodocyclales	206389|Rhodocyclales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
EH2_k127_6065099_1	1123392.AQWL01000004_gene2682	8.381e-61	216.0	COG0457@1|root,COG0457@2|Bacteria,1PXVW@1224|Proteobacteria,2WD6S@28216|Betaproteobacteria,1KSSP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_8
EH2_k127_6065099_0	1238182.C882_2606	2.801e-172	556.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,2TZMH@28211|Alphaproteobacteria,2JZ65@204441|Rhodospirillales	204441|Rhodospirillales	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,Response_reg
EH2_k127_6082780_2	748280.NH8B_3144	1.547e-75	270.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KSIM@206351|Neisseriales	206351|Neisseriales	NU	Type II/IV secretion system protein	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
EH2_k127_6082780_1	1123368.AUIS01000016_gene2552	1.001e-136	445.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2NCMQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	PFAM type II secretion system	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
EH2_k127_6082780_3	323848.Nmul_A2590	7.866e-65	224.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,37356@32003|Nitrosomonadales	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
EH2_k127_6082780_0	1123392.AQWL01000003_gene288	1.245e-138	447.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,1KRE0@119069|Hydrogenophilales	119069|Hydrogenophilales	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
EH2_k127_6085925_4	1123393.KB891330_gene831	1.874e-82	279.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,1KRMP@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Biotin/lipoate A/B protein ligase family	-	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
EH2_k127_6085925_6	1123392.AQWL01000002_gene2030	1.139e-36	139.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,1KTD2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
EH2_k127_6085925_3	62928.azo0181	1.694e-112	370.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,2KVN6@206389|Rhodocyclales	206389|Rhodocyclales	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
EH2_k127_6085925_1	85643.Tmz1t_0242	2.843e-144	471.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,2KVFQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
EH2_k127_6085925_5	62928.azo0179	1.288e-74	267.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KUPW@206389|Rhodocyclales	206389|Rhodocyclales	DM	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
EH2_k127_6085925_2	335283.Neut_1588	2.392e-134	449.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,37261@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
EH2_k127_6085925_0	1123392.AQWL01000002_gene2025	1.521e-144	466.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,1KSAE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
EH2_k127_6101011_3	1163617.SCD_n01543	5.214e-12	78.0	COG4568@1|root,COG4568@2|Bacteria,1P9SY@1224|Proteobacteria	1224|Proteobacteria	K	Modulator of Rho-dependent transcription termination (ROF)	-	-	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	-
EH2_k127_6101011_0	1123393.KB891333_gene2588	1.279e-121	400.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,1KS2H@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
EH2_k127_6101011_2	1123392.AQWL01000007_gene904	5.19e-41	157.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,1KT8D@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
EH2_k127_6101011_1	1454004.AW11_03049	3.735e-76	263.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1KQP9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH2_k127_6103624_2	395494.Galf_2237	1.474e-58	212.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,44V5M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
EH2_k127_6103624_1	395494.Galf_2590	6.33e-71	263.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM yecA family protein	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
EH2_k127_6103624_0	1000565.METUNv1_03823	4.13e-135	436.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,2KUZN@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH2_k127_6103624_3	1163617.SCD_n00507	2.429e-48	178.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
EH2_k127_6103624_4	159087.Daro_1862	0.0005208	49.0	COG3221@1|root,COG3221@2|Bacteria,1R49P@1224|Proteobacteria,2VN1C@28216|Betaproteobacteria,2KVS5@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
EH2_k127_6121983_4	247633.GP2143_00482	9.054e-08	53.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6121983_1	1123393.KB891316_gene1075	2.08e-159	511.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,1KRST@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
EH2_k127_6121983_3	859657.RPSI07_2804	2.213e-33	145.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,1K2NH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
EH2_k127_6121983_0	1163617.SCD_n00848	3.171e-188	592.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
EH2_k127_6121983_2	543728.Vapar_0483	1.848e-51	186.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,4AE14@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
EH2_k127_6122902_3	292415.Tbd_0595	3.149e-12	67.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KRFP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
EH2_k127_6122902_2	1366050.N234_13665	1.184e-53	195.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,1K064@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
EH2_k127_6122902_1	1163617.SCD_n01806	5.065e-101	342.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
EH2_k127_6122902_0	292415.Tbd_0598	6.439e-201	631.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,1KRZV@119069|Hydrogenophilales	119069|Hydrogenophilales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
EH2_k127_6127008_2	583345.Mmol_0988	4.122e-77	261.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_6127008_0	1123393.KB891327_gene472	7.66e-133	429.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Zinc iron permease	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
EH2_k127_6127008_1	748247.AZKH_3142	1.848e-94	315.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KUES@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
EH2_k127_6127008_3	497321.C664_10737	3.863e-53	190.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,2KV8G@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_6154333_0	292415.Tbd_0436	7.686e-277	857.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,1KRAC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
EH2_k127_6154333_1	1158292.JPOE01000002_gene3447	9.978e-21	93.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,1KP38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
EH2_k127_6162127_1	1123392.AQWL01000001_gene1449	2.018e-147	473.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1KRBT@119069|Hydrogenophilales	119069|Hydrogenophilales	CM	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
EH2_k127_6162127_0	1123392.AQWL01000001_gene1448	2.647e-151	484.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,1KRDA@119069|Hydrogenophilales	119069|Hydrogenophilales	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
EH2_k127_6162127_5	883126.HMPREF9710_02254	4.655e-06	57.0	2D0EJ@1|root,32T8E@2|Bacteria,1N5EU@1224|Proteobacteria,2VV4T@28216|Betaproteobacteria,476MC@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6162127_2	631362.Thi970DRAFT_04901	1.291e-98	330.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,1RRHF@1236|Gammaproteobacteria,1X2C6@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
EH2_k127_6162127_4	631362.Thi970DRAFT_04902	9.225e-31	136.0	2BXQF@1|root,32R1T@2|Bacteria,1RJTZ@1224|Proteobacteria,1SUVI@1236|Gammaproteobacteria,1X1W6@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	-
EH2_k127_6162127_3	631362.Thi970DRAFT_04903	6.773e-72	248.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,1S6H0@1236|Gammaproteobacteria,1WX9R@135613|Chromatiales	135613|Chromatiales	P	PFAM Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
EH2_k127_6168020_4	640081.Dsui_1600	1.522e-68	248.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,2KW9U@206389|Rhodocyclales	206389|Rhodocyclales	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
EH2_k127_6168020_5	396588.Tgr7_0028	1.201e-54	203.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales	135613|Chromatiales	H	Uroporphyrinogen III synthase	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
EH2_k127_6168020_2	1121004.ATVC01000023_gene288	5.502e-127	413.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,2KQ5K@206351|Neisseriales	206351|Neisseriales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
EH2_k127_6168020_7	1163617.SCD_n02799	4.112e-31	129.0	COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,2WGR9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF836,Thioredoxin_2,Thioredoxin_7
EH2_k127_6168020_3	1000565.METUNv1_03841	5.824e-69	248.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,2M03Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Alginate biosynthesis regulatory protein AlgR	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
EH2_k127_6168020_0	1123392.AQWL01000002_gene1985	3.183e-231	733.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,1KRB4@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
EH2_k127_6168020_6	1304883.KI912532_gene581	1.626e-35	137.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,2KWZ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the frataxin	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
EH2_k127_6168020_1	1163617.SCD_n00173	6.255e-169	540.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
EH2_k127_6197981_0	1123392.AQWL01000002_gene1949	4.523e-200	632.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KS92@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_6197981_1	292415.Tbd_0198	3.489e-120	395.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c
EH2_k127_6211175_5	1123393.KB891328_gene578	5.454e-46	171.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,1KSET@119069|Hydrogenophilales	119069|Hydrogenophilales	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
EH2_k127_6211175_2	1288494.EBAPG3_7420	1.301e-106	355.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,372DG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_6211175_0	748247.AZKH_4325	1.135e-151	493.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KV3Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN1	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
EH2_k127_6211175_6	1163617.SCD_n00556	5.552e-40	151.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
EH2_k127_6211175_4	76114.ebA3391	3.223e-49	186.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
EH2_k127_6211175_1	1123393.KB891328_gene573	7.829e-124	404.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,1KRJ5@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HPr Serine kinase N terminus	-	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
EH2_k127_6211175_3	279714.FuraDRAFT_2888	1.379e-51	192.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,2KQDY@206351|Neisseriales	206351|Neisseriales	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
EH2_k127_6215158_3	557598.LHK_02244	4.979e-62	214.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,2KPZR@206351|Neisseriales	206351|Neisseriales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
EH2_k127_6215158_2	1123393.KB891316_gene2128	1.542e-85	287.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,1KS2C@119069|Hydrogenophilales	119069|Hydrogenophilales	D	VirC1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
EH2_k127_6215158_0	1123392.AQWL01000006_gene545	1.15e-115	390.0	COG0129@1|root,COG0676@1|root,COG0129@2|Bacteria,COG0676@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,1KS6Q@119069|Hydrogenophilales	119069|Hydrogenophilales	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,ILVD_EDD
EH2_k127_6215158_1	1123392.AQWL01000005_gene3236	3.111e-89	298.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,1KR9Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
EH2_k127_6228183_0	1123368.AUIS01000019_gene1227	2.768e-289	913.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	apc3	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
EH2_k127_6228183_2	292415.Tbd_1220	3.957e-166	524.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,1KRGY@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
EH2_k127_6228183_1	1123393.KB891326_gene240	3.831e-194	628.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,1KS13@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
EH2_k127_6228183_3	1123393.KB891326_gene239	1.002e-74	261.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,1KSGG@119069|Hydrogenophilales	119069|Hydrogenophilales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_6247403_4	1123392.AQWL01000007_gene1007	1.449e-90	309.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KRY7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
EH2_k127_6247403_5	292415.Tbd_0991	1.544e-50	187.0	COG0596@1|root,COG0596@2|Bacteria,1RJQK@1224|Proteobacteria,2W4YC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6247403_6	557598.LHK_01826	3.459e-39	151.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KQYW@206351|Neisseriales	206351|Neisseriales	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
EH2_k127_6247403_8	1163617.SCD_n01605	4.918e-24	109.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,2VVZG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6247403_0	1123393.KB891329_gene1049	8.685e-237	745.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria,1KSQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
EH2_k127_6247403_1	1123392.AQWL01000001_gene1634	1.011e-196	617.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1KS4U@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
EH2_k127_6247403_2	292415.Tbd_0950	1.655e-186	590.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
EH2_k127_6247403_3	305700.B447_01101	4.882e-121	399.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KUSW@206389|Rhodocyclales	206389|Rhodocyclales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
EH2_k127_6247403_7	1121004.ATVC01000065_gene1604	1.786e-35	140.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,2KQ1M@206351|Neisseriales	206351|Neisseriales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
EH2_k127_6271091_3	228410.NE2219	2.866e-63	222.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
EH2_k127_6271091_1	62928.azo2209	2.404e-91	312.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
EH2_k127_6271091_2	1123392.AQWL01000006_gene559	7.887e-74	254.0	2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,2W2XB@28216|Betaproteobacteria,1KSXF@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6271091_4	1123393.KB891316_gene1345	2.689e-60	219.0	COG0501@1|root,COG0501@2|Bacteria,1N5MJ@1224|Proteobacteria,2WBRD@28216|Betaproteobacteria,1KSF6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6271091_5	1218352.B597_003720	1.538e-48	185.0	COG5581@1|root,COG5581@2|Bacteria,1RCY3@1224|Proteobacteria,1S45F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
EH2_k127_6271091_0	1163617.SCD_n01864	1.644e-152	484.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
EH2_k127_6271091_6	1123226.KB899278_gene572	3.115e-27	122.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1UQA9@1239|Firmicutes,4HBNE@91061|Bacilli	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9
EH2_k127_6272113_4	396588.Tgr7_1014	1.094e-89	298.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1WW9S@135613|Chromatiales	135613|Chromatiales	E	Bacterial transglutaminase-like N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
EH2_k127_6272113_5	595537.Varpa_2411	3.545e-65	230.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,2VQEC@28216|Betaproteobacteria,4ADVM@80864|Comamonadaceae	28216|Betaproteobacteria	F	Peptidase C26	guaA_2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
EH2_k127_6272113_3	1344012.ATMI01000054_gene1636	5.731e-100	333.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria,4BTIK@82986|Tatumella	1236|Gammaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
EH2_k127_6272113_1	666681.M301_0034	1.462e-211	662.0	COG3185@1|root,COG3185@2|Bacteria,1R5AJ@1224|Proteobacteria,2W11Y@28216|Betaproteobacteria,2KKMU@206350|Nitrosomonadales	206350|Nitrosomonadales	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6272113_2	637389.Acaty_m0029	6.803e-114	375.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,2NC5M@225057|Acidithiobacillales	225057|Acidithiobacillales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
EH2_k127_6272113_0	1485544.JQKP01000020_gene70	1.284e-232	724.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,44W6Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
EH2_k127_6274065_6	1123392.AQWL01000001_gene1361	2.109e-52	197.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria,1KS9C@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
EH2_k127_6274065_5	1123393.KB891316_gene1426	8.83e-57	201.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria,1KT3T@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_6274065_4	1163617.SCD_n00828	9.352e-67	247.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,2VSBD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6274065_3	522306.CAP2UW1_3828	7.562e-76	263.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria,1KR46@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB1	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH2_k127_6274065_1	1163617.SCD_n01267	8.274e-101	333.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH2_k127_6274065_2	292415.Tbd_1180	3.814e-84	285.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,1KS9X@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
EH2_k127_6274065_8	640081.Dsui_1725	2.184e-10	72.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,2KUF4@206389|Rhodocyclales	206389|Rhodocyclales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA
EH2_k127_6274065_7	1163617.SCD_n01264	2.181e-24	105.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
EH2_k127_6274065_0	1163617.SCD_n01264	5.189e-102	344.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
EH2_k127_6276716_0	522306.CAP2UW1_0607	1.53e-307	955.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KQDX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	mdtC	-	-	ko:K03296,ko:K07788,ko:K07789,ko:K21133	ko02020,map02020	M00648,M00822	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2,2.A.6.2.35	-	-	ACR_tran
EH2_k127_6280415_3	748247.AZKH_2828	4.286e-37	141.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,2KW4F@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
EH2_k127_6280415_0	279714.FuraDRAFT_3033	3.405e-242	766.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,2KPQ4@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
EH2_k127_6280415_4	292415.Tbd_0702	5.112e-25	106.0	COG1942@1|root,COG1942@2|Bacteria,1PU0F@1224|Proteobacteria,2WANX@28216|Betaproteobacteria,1KTEB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
EH2_k127_6280415_2	292415.Tbd_0703	1.319e-82	284.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2VQ3T@28216|Betaproteobacteria	28216|Betaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
EH2_k127_6280415_1	85643.Tmz1t_2657	6.767e-127	418.0	28I8W@1|root,2Z8BP@2|Bacteria,1N0SC@1224|Proteobacteria,2VK0J@28216|Betaproteobacteria,2KVDQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2863
EH2_k127_6280415_5	292415.Tbd_0726	0.0001614	44.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	cation diffusion facilitator family transporter	zitB	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_6,Cation_efflux
EH2_k127_6284680_1	1207076.ALAT01000011_gene1557	1.531e-156	497.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1Z0JK@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH2_k127_6284680_0	292415.Tbd_2447	3.421e-160	509.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KRX2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH2_k127_6284680_4	1485544.JQKP01000003_gene120	4.937e-23	113.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_6284680_3	159087.Daro_3353	2.049e-40	166.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2VR6A@28216|Betaproteobacteria,2KWI6@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
EH2_k127_6284680_2	522306.CAP2UW1_4238	2.572e-105	360.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	yfgF	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
EH2_k127_6289072_0	580332.Slit_2486	0.0	1655.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,2W99Y@28216|Betaproteobacteria,44WKY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
EH2_k127_6289072_3	580332.Slit_2487	2.877e-134	433.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,2VKNM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
EH2_k127_6289072_2	580332.Slit_2488	2.666e-152	487.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VM3P@28216|Betaproteobacteria,44W59@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_6289072_4	1123399.AQVE01000010_gene3247	7.605e-77	269.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,460FM@72273|Thiotrichales	72273|Thiotrichales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
EH2_k127_6289072_5	1485544.JQKP01000003_gene144	5.421e-67	236.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
EH2_k127_6289072_6	545276.KB898728_gene197	2.166e-36	150.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
EH2_k127_6289072_1	1095769.CAHF01000005_gene1469	1.646e-291	908.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
EH2_k127_628995_2	1163617.SCD_n01089	1.771e-21	94.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
EH2_k127_628995_1	1163617.SCD_n01089	2.916e-49	181.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
EH2_k127_628995_0	1288494.EBAPG3_20760	2.5e-99	331.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2VTN7@28216|Betaproteobacteria,372A7@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
EH2_k127_6320280_2	1148.1001258	1.097e-07	58.0	COG3895@1|root,COG3895@2|Bacteria,1GFWT@1117|Cyanobacteria,1H6MX@1142|Synechocystis	1117|Cyanobacteria	S	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	MliC
EH2_k127_6320280_0	1304883.KI912532_gene771	1.272e-183	584.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,2KUPM@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function DUF21	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
EH2_k127_6320280_1	375286.mma_0726	4.083e-86	291.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,472Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Probable molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
EH2_k127_6328179_17	1123392.AQWL01000004_gene2831	1.147e-36	142.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2VU4G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
EH2_k127_6328179_6	1163617.SCD_n00522	4.592e-115	373.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria	28216|Betaproteobacteria	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
EH2_k127_6328179_14	1502770.JQMG01000001_gene1494	7.507e-81	277.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,2KN0E@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
EH2_k127_6328179_11	573.JG24_06935	5.244e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
EH2_k127_6328179_5	477184.KYC_11713	2.853e-144	473.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,2VHKW@28216|Betaproteobacteria,3T6DM@506|Alcaligenaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
EH2_k127_6328179_4	1123393.KB891316_gene1260	2.127e-157	501.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KSYR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
EH2_k127_6328179_3	582744.Msip34_0044	3.075e-161	520.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KM1J@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
EH2_k127_6328179_10	1123393.KB891328_gene517	2.43e-106	350.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1KRM5@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
EH2_k127_6328179_9	626418.bglu_1g08280	1.084e-106	350.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,1K0EK@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
EH2_k127_6328179_12	1123393.KB891328_gene515	3.029e-90	306.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KS5M@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
EH2_k127_6328179_8	1123392.AQWL01000004_gene2842	8.526e-112	368.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KSJI@119069|Hydrogenophilales	119069|Hydrogenophilales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
EH2_k127_6328179_13	1163617.SCD_n00514	5.574e-87	297.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
EH2_k127_6328179_15	1288826.MSNKSG1_17386	1.763e-76	267.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
EH2_k127_6328179_16	640081.Dsui_3246	1.406e-52	192.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,2KWJ5@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
EH2_k127_6328179_19	640081.Dsui_3247	3.71e-23	104.0	2DNMC@1|root,32Y3R@2|Bacteria,1N8DI@1224|Proteobacteria,2VVNN@28216|Betaproteobacteria,2KXCE@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2788
EH2_k127_6328179_0	1123393.KB891316_gene1133	2.865e-255	791.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KSBA@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
EH2_k127_6328179_18	1123393.KB891316_gene1134	1.493e-28	117.0	2AFYM@1|root,3162D@2|Bacteria,1PWQV@1224|Proteobacteria,2WC9G@28216|Betaproteobacteria,1KTA5@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
EH2_k127_6328179_1	1123393.KB891316_gene1135	1.038e-174	569.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1KRGB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
EH2_k127_6328179_2	582744.Msip34_1561	5.35e-174	554.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KM17@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH2_k127_6328179_7	243233.MCA2870	2.674e-112	370.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XDNC@135618|Methylococcales	135618|Methylococcales	EH	synthase component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_6359148_4	292415.Tbd_1420	1.236e-41	155.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1KSC1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
EH2_k127_6359148_3	1123393.KB891331_gene2902	6.645e-98	326.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,1KRNT@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
EH2_k127_6359148_1	1123393.KB891327_gene369	9.93e-204	649.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,1KRIN@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
EH2_k127_6359148_2	1123393.KB891326_gene170	1.958e-108	357.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1KRFF@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Pterin binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
EH2_k127_6359148_0	748247.AZKH_3077	1.895e-263	816.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
EH2_k127_6379842_0	930169.B5T_01546	1.515e-161	523.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XI1F@135619|Oceanospirillales	135619|Oceanospirillales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_6379842_5	876269.ARWA01000001_gene2557	0.0006664	49.0	2ED3M@1|root,3370H@2|Bacteria,1NB6I@1224|Proteobacteria,2UE8V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6379842_3	159087.Daro_1973	1.243e-82	280.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
EH2_k127_6379842_2	1163617.SCD_n01758	1.143e-103	343.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
EH2_k127_6379842_4	1304883.KI912532_gene2329	2.055e-64	229.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,2VRE4@28216|Betaproteobacteria,2KWM9@206389|Rhodocyclales	206389|Rhodocyclales	S	AMMECR1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
EH2_k127_6379842_1	1163617.SCD_n01760	6.345e-116	385.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
EH2_k127_6398570_1	1123393.KB891329_gene1064	7.605e-41	155.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,2WGQ3@28216|Betaproteobacteria,1KSIT@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
EH2_k127_6398570_0	292415.Tbd_1439	2.6e-190	619.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	U	type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N
EH2_k127_6398570_2	748280.NH8B_3140	4.398e-21	100.0	2E5FR@1|root,3307F@2|Bacteria,1N89J@1224|Proteobacteria,2VVS4@28216|Betaproteobacteria,2KTJ7@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6398570_3	159087.Daro_3226	7.417e-14	77.0	COG3167@1|root,COG3167@2|Bacteria,1NEXJ@1224|Proteobacteria,2VX69@28216|Betaproteobacteria,2KXE3@206389|Rhodocyclales	206389|Rhodocyclales	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6432369_2	207954.MED92_10439	4.119e-38	148.0	COG2703@1|root,COG2703@2|Bacteria,1N1XS@1224|Proteobacteria,1SAVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	hemerythrin-like metal-binding	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
EH2_k127_6432369_1	1163617.SCD_n01958	5.161e-316	991.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
EH2_k127_6432369_0	93220.LV28_18855	0.0	1077.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,1K0R8@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
EH2_k127_6432369_3	768671.ThimaDRAFT_1361	1.145e-15	84.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1WYSZ@135613|Chromatiales	135613|Chromatiales	D	PFAM Sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH2_k127_6448308_6	497321.C664_19396	1.156e-08	60.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
EH2_k127_6448308_0	1123393.KB891316_gene1835	0.0	1885.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,2VN9C@28216|Betaproteobacteria,1KRXT@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
EH2_k127_6448308_2	1123392.AQWL01000005_gene3212	6.629e-155	496.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,2VK6N@28216|Betaproteobacteria,1KSMP@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Dihydroorotate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DHO_dh
EH2_k127_6448308_5	1123367.C666_04355	8.299e-67	244.0	COG0515@1|root,COG0515@2|Bacteria,1MXX9@1224|Proteobacteria,2VHSR@28216|Betaproteobacteria,2KVD9@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core	-	-	-	ko:K02848	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Kdo
EH2_k127_6448308_4	1123367.C666_04360	4.985e-102	344.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,2VJET@28216|Betaproteobacteria,2KUQ5@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
EH2_k127_6448308_1	292415.Tbd_2506	1.657e-195	620.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
EH2_k127_6448308_3	265072.Mfla_0771	4.958e-130	421.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KKPF@206350|Nitrosomonadales	206350|Nitrosomonadales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
EH2_k127_6462428_2	757424.Hsero_1916	1.545e-36	147.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,472QE@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	CBS-domain-containing membrane protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
EH2_k127_6462428_1	870187.Thini_1252	5.337e-86	309.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,462H9@72273|Thiotrichales	72273|Thiotrichales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
EH2_k127_6462428_0	1123393.KB891326_gene122	8.423e-148	480.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KSZK@119069|Hydrogenophilales	119069|Hydrogenophilales	T	GAF domain	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_3,HAMP,HATPase_c,HisKA_3,PilJ
EH2_k127_6463987_4	314607.KB13_954	1.591e-43	162.0	COG2227@1|root,COG2227@2|Bacteria,1QYVF@1224|Proteobacteria	1224|Proteobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6463987_2	62928.azo0588	2.12e-56	202.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria,2VVE7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6463987_0	1123393.KB891326_gene83	3.654e-276	858.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
EH2_k127_6463987_1	697282.Mettu_0389	1.152e-59	213.0	COG2236@1|root,COG2236@2|Bacteria,1RKB0@1224|Proteobacteria,1S7J1@1236|Gammaproteobacteria,1XFMX@135618|Methylococcales	135618|Methylococcales	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
EH2_k127_6463987_3	1005048.CFU_3489	3.148e-47	175.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,472QE@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	CBS-domain-containing membrane protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
EH2_k127_6478437_5	247634.GPB2148_387	2.262e-11	70.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1J52F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0099133,GO:1901265,GO:1901363	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	iECNA114_1301.ECNA114_0696,iECSF_1327.ECSF_0691,iUMNK88_1353.UMNK88_805	ABC_tran,TOBE
EH2_k127_6478437_2	32042.PstZobell_14071	3.171e-106	350.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1Z2MZ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	COG4149 ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
EH2_k127_6478437_3	243233.MCA1378	4.645e-104	344.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1XE8A@135618|Methylococcales	1236|Gammaproteobacteria	P	molybdenum ABC transporter, periplasmic	modA-2	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
EH2_k127_6478437_0	713587.THITH_00810	1.744e-120	389.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
EH2_k127_6478437_1	1283300.ATXB01000001_gene2242	8.046e-119	398.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S6JM@1236|Gammaproteobacteria,1XE76@135618|Methylococcales	135618|Methylococcales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
EH2_k127_6478437_6	273075.Ta0823	1.766e-07	56.0	COG0406@1|root,arCOG01991@2157|Archaea,2Y23H@28890|Euryarchaeota,2428S@183967|Thermoplasmata	183967|Thermoplasmata	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
EH2_k127_6486100_2	1123392.AQWL01000001_gene1479	1.347e-106	351.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1KRAD@119069|Hydrogenophilales	119069|Hydrogenophilales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
EH2_k127_6486100_3	1163617.SCD_n00821	1.557e-100	331.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
EH2_k127_6486100_1	1304883.KI912532_gene3080	3.035e-190	597.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,2KUKK@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
EH2_k127_6486100_4	314607.KB13_289	5.032e-74	262.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KPXQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Acetolactate synthase I III small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
EH2_k127_6486100_0	1163617.SCD_n00818	1.802e-308	951.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
EH2_k127_6486100_5	1485544.JQKP01000003_gene120	1.05e-27	123.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_6497505_3	1120999.JONM01000026_gene1554	1.745e-119	391.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KQ0F@206351|Neisseriales	206351|Neisseriales	C	FAD binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
EH2_k127_6497505_4	1236959.BAMT01000006_gene336	1.948e-40	156.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,2KMX4@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
EH2_k127_6497505_5	1304883.KI912532_gene956	4.06e-32	128.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphotransferase System	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
EH2_k127_6497505_0	292415.Tbd_2414	2.208e-224	713.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,1KRAA@119069|Hydrogenophilales	119069|Hydrogenophilales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
EH2_k127_6497505_2	1120999.JONM01000005_gene3915	5.333e-124	418.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,2VKGP@28216|Betaproteobacteria,2KSCH@206351|Neisseriales	206351|Neisseriales	T	Sigma factor PP2C-like phosphatases	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
EH2_k127_6497505_6	640081.Dsui_1714	1.501e-30	124.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,2VWS3@28216|Betaproteobacteria,2KX88@206389|Rhodocyclales	206389|Rhodocyclales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
EH2_k127_6497505_1	388051.AUFE01000096_gene3034	1.53e-124	405.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,1K0VA@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
EH2_k127_6505422_0	522306.CAP2UW1_2602	2.3e-118	397.0	COG2202@1|root,COG2703@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
EH2_k127_6505422_1	580332.Slit_1183	9.016e-82	282.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,44WNG@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
EH2_k127_6505422_2	1047013.AQSP01000140_gene2511	4.32e-23	109.0	COG2202@1|root,COG2203@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3920@2|Bacteria,2NPS5@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936,ko:K02030	-	M00236,M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS_3,PAS_9
EH2_k127_6520960_8	1123393.KB891316_gene1656	5.981e-63	226.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1KSHU@119069|Hydrogenophilales	119069|Hydrogenophilales	CH	FAD binding domain	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
EH2_k127_6520960_0	1123393.KB891316_gene1657	1.233e-203	641.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,1KS63@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
EH2_k127_6520960_6	85643.Tmz1t_1452	3.357e-83	286.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KV5Z@206389|Rhodocyclales	206389|Rhodocyclales	JM	Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
EH2_k127_6520960_4	292415.Tbd_2336	1.673e-140	456.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1KRX6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
EH2_k127_6520960_1	1123392.AQWL01000005_gene3071	3.526e-192	625.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,1KRHD@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
EH2_k127_6520960_3	1163617.SCD_n02560	6.422e-147	477.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
EH2_k127_6520960_9	557598.LHK_02520	1.974e-58	213.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,2VV8V@28216|Betaproteobacteria,2KRHP@206351|Neisseriales	206351|Neisseriales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
EH2_k127_6520960_2	1123392.AQWL01000011_gene2252	3.61e-178	570.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria,1KRY8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
EH2_k127_6520960_7	1485544.JQKP01000007_gene1971	2.618e-71	250.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,44VZS@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
EH2_k127_6520960_5	62928.azo1078	8.99e-102	334.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,2KV43@206389|Rhodocyclales	206389|Rhodocyclales	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
EH2_k127_652435_2	522306.CAP2UW1_0969	3.042e-89	296.0	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria,2VMEZ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
EH2_k127_652435_0	522306.CAP2UW1_0970	2.619e-117	389.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,2VS3H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
EH2_k127_652435_3	522306.CAP2UW1_0971	1.097e-88	297.0	COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,2VQ2E@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_8
EH2_k127_652435_4	1163617.SCD_n01866	1.754e-68	236.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
EH2_k127_652435_1	1123393.KB891333_gene2640	4.321e-104	347.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KSR8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
EH2_k127_6540046_0	62928.azo1659	4.962e-205	648.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,2KV6T@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA binding	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
EH2_k127_65420_1	1123367.C666_08835	4.601e-19	93.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KUGD@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3850 Signal transduction histidine kinase, nitrate nitrite-specific	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
EH2_k127_65420_0	76114.ebA3504	5.274e-44	177.0	COG0664@1|root,COG0664@2|Bacteria,1RIIE@1224|Proteobacteria,2VTJF@28216|Betaproteobacteria,2KWQM@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	dnrE	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
EH2_k127_6546233_2	1123392.AQWL01000009_gene1089	1.152e-42	157.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1KS32@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
EH2_k127_6546233_1	1123393.KB891329_gene1041	9.985e-63	229.0	COG3439@1|root,COG3439@2|Bacteria,1Q7MF@1224|Proteobacteria,2WBHI@28216|Betaproteobacteria,1KRXN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
EH2_k127_6546233_0	1123392.AQWL01000008_gene1211	2.209e-85	287.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1KRN8@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
EH2_k127_6553237_3	1123393.KB891327_gene289	6.146e-35	139.0	COG3449@1|root,COG3449@2|Bacteria,1N79X@1224|Proteobacteria,2VWWR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6553237_1	1123392.AQWL01000003_gene472	1.522e-53	202.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,1KSZF@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobD/Cbib protein	-	-	-	-	-	-	-	-	-	-	-	-	CobD_Cbib
EH2_k127_6553237_0	1123393.KB891327_gene291	1.169e-174	556.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,1KRGF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
EH2_k127_6553237_2	1158318.ATXC01000002_gene1536	1.938e-44	167.0	COG2199@1|root,COG3706@2|Bacteria,2G51D@200783|Aquificae	200783|Aquificae	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
EH2_k127_6558292_1	1123393.KB891331_gene2999	2.307e-173	551.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VHP4@28216|Betaproteobacteria,1KS8N@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
EH2_k127_6558292_0	1163617.SCD_n00481	9.609e-248	782.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
EH2_k127_6558292_3	1163617.SCD_n00480	4.35e-77	264.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH2_k127_6558292_4	1123392.AQWL01000002_gene1813	5.198e-40	149.0	COG4327@1|root,COG4327@2|Bacteria,1NQBY@1224|Proteobacteria,2VV4C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
EH2_k127_6558292_2	1123392.AQWL01000002_gene1812	4.369e-163	520.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,1KS58@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
EH2_k127_6571802_3	76114.ebA2963	2.977e-103	337.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
EH2_k127_6571802_6	305700.B447_05650	3.703e-32	132.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,2KWJJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
EH2_k127_6571802_1	1123392.AQWL01000002_gene1703	4.788e-121	398.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KRGG@119069|Hydrogenophilales	119069|Hydrogenophilales	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
EH2_k127_6571802_4	1123393.KB891332_gene2765	1.678e-91	314.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,1KSSH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
EH2_k127_6571802_5	1502770.JQMG01000001_gene642	3.043e-70	241.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,2KMM5@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
EH2_k127_6571802_2	748247.AZKH_0057	6.034e-113	379.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KVNV@206389|Rhodocyclales	206389|Rhodocyclales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
EH2_k127_6571802_0	93220.LV28_10865	1.371e-121	393.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1K092@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_6582026_1	395493.BegalDRAFT_1258	1.337e-136	441.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
EH2_k127_6582026_0	85643.Tmz1t_4080	2.567e-184	581.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,2KV0I@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
EH2_k127_6582026_3	1123392.AQWL01000006_gene554	8.26e-05	54.0	2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria,1KTFI@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6582026_2	323848.Nmul_A0626	1.094e-30	123.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,373CS@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
EH2_k127_6589130_1	713587.THITH_02080	2.936e-33	134.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1WY76@135613|Chromatiales	135613|Chromatiales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
EH2_k127_6589130_2	1123368.AUIS01000021_gene983	2.562e-28	121.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,2ND8W@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
EH2_k127_6589130_0	1163617.SCD_n00318	7.005e-45	177.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
EH2_k127_6605579_0	1163617.SCD_n01923	1.83e-210	670.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
EH2_k127_6605579_1	1163617.SCD_n01922	1.909e-43	164.0	COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_6605579_3	640081.Dsui_2885	1.67e-14	80.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
EH2_k127_6605579_2	1430440.MGMSRv2_1230	2.448e-19	89.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2U2AJ@28211|Alphaproteobacteria,2JTY7@204441|Rhodospirillales	204441|Rhodospirillales	KT	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
EH2_k127_6618132_0	1123392.AQWL01000009_gene1087	3.771e-152	484.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KRCI@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
EH2_k127_6618132_1	929556.Solca_3998	5.351e-45	176.0	COG3324@1|root,COG3324@2|Bacteria,4NZ00@976|Bacteroidetes	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
EH2_k127_6622354_5	1304883.KI912532_gene1079	4.197e-58	207.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KWH7@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
EH2_k127_6622354_4	1121004.ATVC01000004_gene1494	3.001e-58	206.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KR4E@206351|Neisseriales	206351|Neisseriales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
EH2_k127_6622354_0	1163617.SCD_n02785	1.48e-252	783.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-CoA carboxylase biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
EH2_k127_6622354_2	1120999.JONM01000002_gene553	4.03e-107	354.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,2KPSR@206351|Neisseriales	206351|Neisseriales	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
EH2_k127_6622354_6	204773.HEAR2765	2.394e-34	144.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,473BQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
EH2_k127_6622354_3	1158165.KB898875_gene94	1.462e-84	292.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
EH2_k127_6622354_1	292415.Tbd_0178	3.385e-170	541.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,1KSB0@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
EH2_k127_6624486_1	1123393.KB891316_gene1118	2.313e-90	308.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2W1SC@28216|Betaproteobacteria,1KSI9@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
EH2_k127_6624486_0	316067.Geob_1385	4.198e-130	428.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
EH2_k127_6624486_2	1123392.AQWL01000009_gene1106	6.589e-69	244.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,1KSS1@119069|Hydrogenophilales	119069|Hydrogenophilales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
EH2_k127_6624486_4	305700.B447_07277	1.519e-36	149.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,2KWRI@206389|Rhodocyclales	206389|Rhodocyclales	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
EH2_k127_6624486_3	1485544.JQKP01000002_gene1365	9.674e-49	175.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
EH2_k127_6627384_0	292415.Tbd_2165	1.67e-197	617.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,1KRIF@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
EH2_k127_6627384_4	1123392.AQWL01000005_gene2903	2.338e-63	222.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,1KSP2@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
EH2_k127_6627384_1	292415.Tbd_2168	3.25e-155	503.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KS4K@119069|Hydrogenophilales	119069|Hydrogenophilales	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
EH2_k127_6627384_2	1123393.KB891316_gene1481	1.051e-84	305.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,1KSWC@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_6627384_3	292415.Tbd_2189	3.95e-77	263.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1KSH3@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
EH2_k127_6627384_5	305700.B447_11727	8.452e-48	181.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,2KUGQ@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
EH2_k127_663099_2	1163617.SCD_n01218	1.016e-45	168.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
EH2_k127_663099_1	640081.Dsui_1458	3.654e-46	171.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,2KWCC@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
EH2_k127_663099_0	279714.FuraDRAFT_3346	5.085e-126	407.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,2VM49@28216|Betaproteobacteria,2KQGX@206351|Neisseriales	206351|Neisseriales	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
EH2_k127_6631572_2	870187.Thini_0154	7.881e-78	268.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,1S09M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OQ	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_6631572_0	292415.Tbd_2143	1.963e-83	282.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1KRNC@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
EH2_k127_6631572_1	1454004.AW11_00537	1.347e-79	268.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,1KQ14@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
EH2_k127_6643178_2	1123392.AQWL01000004_gene2687	9.226e-110	356.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,1KRBE@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
EH2_k127_6643178_1	267608.RSc1225	8.514e-123	406.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,1K0TV@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
EH2_k127_6643178_3	1163617.SCD_n01798	6.739e-17	81.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
EH2_k127_6643178_0	1123393.KB891328_gene645	1.299e-129	421.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,1KRFA@119069|Hydrogenophilales	119069|Hydrogenophilales	O	prohibitin homologues	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
EH2_k127_6646288_7	1158165.KB898878_gene2570	1.273e-17	83.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
EH2_k127_6646288_0	1158165.KB898872_gene1135	3.64e-294	924.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1RWY1@1236|Gammaproteobacteria,1X06S@135613|Chromatiales	135613|Chromatiales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9
EH2_k127_6646288_6	1266908.AQPB01000053_gene603	3.445e-33	151.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXR1@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
EH2_k127_6646288_1	1158762.KB898039_gene1706	1.02e-277	901.0	COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg
EH2_k127_6646288_2	765914.ThisiDRAFT_0321	2.407e-138	450.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WXHR@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
EH2_k127_6646288_5	292415.Tbd_1027	2.361e-65	228.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KRQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
EH2_k127_6646288_4	522306.CAP2UW1_0972	4.294e-97	321.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
EH2_k127_6646288_3	522306.CAP2UW1_0973	6.909e-103	358.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
EH2_k127_6661112_0	335283.Neut_1176	7.011e-193	604.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,373TP@32003|Nitrosomonadales	28216|Betaproteobacteria	F	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
EH2_k127_6661112_2	292415.Tbd_2576	2.654e-84	293.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,1KSQ3@119069|Hydrogenophilales	119069|Hydrogenophilales	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
EH2_k127_6661112_1	292415.Tbd_2575	2.44e-156	503.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,1KS9B@119069|Hydrogenophilales	119069|Hydrogenophilales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
EH2_k127_6672625_9	1123393.KB891328_gene604	9.899e-13	68.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,1KT6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
EH2_k127_6672625_3	1123392.AQWL01000002_gene1762	5.118e-97	322.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,1KS8R@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
EH2_k127_6672625_10	472759.Nhal_0059	2.226e-10	66.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_6672625_4	1123368.AUIS01000019_gene1210	2.884e-51	188.0	COG3658@1|root,COG3658@2|Bacteria	2|Bacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
EH2_k127_6672625_6	1123368.AUIS01000019_gene1208	4.333e-33	135.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Di-haem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
EH2_k127_6672625_8	1123392.AQWL01000002_gene1757	8.199e-24	108.0	2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria,2W6NA@28216|Betaproteobacteria,1KT6V@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6672625_7	1121035.AUCH01000009_gene844	3.112e-24	105.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,2KX8R@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
EH2_k127_6672625_0	1123393.KB891316_gene1686	3.167e-170	544.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
EH2_k127_6672625_2	1123392.AQWL01000005_gene3099	1.338e-102	343.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KSKP@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
EH2_k127_6672625_1	1123393.KB891316_gene1688	2.1e-157	518.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1KSXX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
EH2_k127_6672625_5	1123392.AQWL01000005_gene3093	1.069e-41	160.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,1KSWM@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
EH2_k127_6723524_1	292415.Tbd_0563	9.863e-116	385.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KSXW@119069|Hydrogenophilales	119069|Hydrogenophilales	F	5'-nucleotidase, C-terminal domain	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
EH2_k127_6723524_0	292415.Tbd_0564	3.207e-123	402.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,1KSVE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
EH2_k127_6723524_3	292415.Tbd_0565	5.495e-40	150.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,1KT6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
EH2_k127_6723524_2	292415.Tbd_0566	1.418e-50	183.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1KT0V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
EH2_k127_6726770_0	1458275.AZ34_07565	9.841e-68	243.0	COG0789@1|root,COG0789@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,4ACBQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
EH2_k127_6726770_3	472759.Nhal_0059	3.805e-10	67.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_6726770_2	580332.Slit_1015	2.327e-31	128.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
EH2_k127_6726770_1	1123393.KB891331_gene2937	7.343e-32	130.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KSP1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
EH2_k127_6747684_4	204773.HEAR1902	5.094e-13	74.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,2VR6V@28216|Betaproteobacteria,4747J@75682|Oxalobacteraceae	28216|Betaproteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
EH2_k127_6747684_0	580332.Slit_0621	3.598e-123	414.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,44UZ9@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
EH2_k127_6747684_3	1163617.SCD_n01704	4.779e-34	138.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2VUJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
EH2_k127_6747684_1	1304883.KI912532_gene157	7.11e-47	171.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2VSK1@28216|Betaproteobacteria,2KWN2@206389|Rhodocyclales	206389|Rhodocyclales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_6747684_2	1123487.KB892867_gene1058	4.552e-45	169.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria,2KWMP@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
EH2_k127_6784045_6	1163617.SCD_n01615	2.069e-28	119.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
EH2_k127_6784045_9	360095.BARBAKC583_1300	1.929e-08	56.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6784045_8	202952.BBLI01000008_gene828	2.194e-09	59.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6784045_4	1121035.AUCH01000022_gene3203	7.051e-42	164.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,2KWZK@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6784045_5	640081.Dsui_0452	5.476e-38	150.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,2KWQI@206389|Rhodocyclales	206389|Rhodocyclales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
EH2_k127_6784045_3	1163617.SCD_n00058	2.527e-66	235.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
EH2_k127_6784045_1	1123392.AQWL01000005_gene3188	3.889e-233	733.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1KS2N@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
EH2_k127_6784045_2	1163617.SCD_n00055	1.729e-93	319.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
EH2_k127_6784045_7	62928.azo3216	7.473e-26	112.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,2KWYS@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
EH2_k127_6784045_0	323848.Nmul_A0511	2.459e-260	814.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,372EP@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
EH2_k127_6786330_2	292415.Tbd_0022	2.399e-79	267.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KSYA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH2_k127_6786330_0	292415.Tbd_0022	7.437e-201	636.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KSYA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
EH2_k127_6786330_1	1123392.AQWL01000003_gene493	4.906e-90	301.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,1KRIY@119069|Hydrogenophilales	119069|Hydrogenophilales	E	AIR synthase related protein, N-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
EH2_k127_6790725_2	1163617.SCD_n00916	7.929e-33	131.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
EH2_k127_6790725_1	748247.AZKH_3085	7.666e-66	228.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KWB1@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
EH2_k127_6790725_0	640081.Dsui_3072	1.657e-126	419.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KUDS@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
EH2_k127_6806017_0	292415.Tbd_1189	2.597e-21	103.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1KS8C@119069|Hydrogenophilales	119069|Hydrogenophilales	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
EH2_k127_6815283_3	85643.Tmz1t_2205	3.681e-39	145.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KUBJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
EH2_k127_6815283_0	1163617.SCD_n01256	3.32e-71	243.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
EH2_k127_6815283_2	243365.CV_1092	2.531e-49	180.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KRA2@206351|Neisseriales	206351|Neisseriales	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
EH2_k127_6815283_1	1163617.SCD_n01258	1.192e-55	199.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
EH2_k127_6815283_4	395494.Galf_0648	3.326e-27	111.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
EH2_k127_685087_1	1144275.COCOR_02865	9.587e-82	275.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WM12@28221|Deltaproteobacteria,2YUQG@29|Myxococcales	28221|Deltaproteobacteria	S	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
EH2_k127_685087_4	748247.AZKH_1515	1.302e-35	142.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VHQF@28216|Betaproteobacteria,2KXV9@206389|Rhodocyclales	206389|Rhodocyclales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
EH2_k127_685087_5	1231392.OCGS_2230	3.577e-16	88.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TTCJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
EH2_k127_685087_2	1123392.AQWL01000009_gene1074	3.347e-67	231.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VRGX@28216|Betaproteobacteria,1KTD8@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
EH2_k127_685087_3	522306.CAP2UW1_1578	2.911e-51	186.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,2VU9B@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
EH2_k127_685087_0	1123392.AQWL01000003_gene260	6.377e-210	669.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
EH2_k127_6873134_0	1003200.AXXA_30032	5.463e-93	310.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,3T3A0@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_6873134_1	204773.HEAR2463	3.431e-46	169.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,473EN@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	branched-chain amino acid	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
EH2_k127_6877461_1	265072.Mfla_0982	6.086e-113	374.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,2KKDU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	SMART transcription factor jumonji jmjC domain protein	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
EH2_k127_6877461_4	1123393.KB891328_gene627	3.733e-67	231.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,1KSSB@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_6877461_5	1123392.AQWL01000004_gene2709	3.44e-58	206.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,1KRPX@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
EH2_k127_6877461_0	1123393.KB891328_gene629	3.024e-156	498.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,1KRXB@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
EH2_k127_6877461_2	292415.Tbd_0589	1.137e-94	326.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,1KRQD@119069|Hydrogenophilales	119069|Hydrogenophilales	D	TilS substrate binding domain	-	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
EH2_k127_6877461_7	1121004.ATVC01000020_gene30	1.122e-10	70.0	COG3147@1|root,COG3147@2|Bacteria,1QYE8@1224|Proteobacteria,2WHED@28216|Betaproteobacteria,2KRYS@206351|Neisseriales	206351|Neisseriales	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
EH2_k127_6877461_3	1095769.CAHF01000011_gene2402	1.103e-70	246.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4741A@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
EH2_k127_6877461_6	1121351.AUAP01000002_gene498	1.433e-57	205.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KPVD@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
EH2_k127_6878123_0	1123393.KB891316_gene1402	2.62e-46	169.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1KRJZ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_6878123_2	748247.AZKH_2843	5.042e-09	64.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,2KXA7@206389|Rhodocyclales	206389|Rhodocyclales	T	Anti sigma-E protein RseA	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
EH2_k127_6878123_1	1000565.METUNv1_00626	1.227e-27	125.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma E regulatory protein, MucB RseB	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
EH2_k127_6945189_2	83406.HDN1F_03060	5.088e-65	226.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J7ZK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
EH2_k127_6945189_1	1485544.JQKP01000008_gene1756	8.432e-96	330.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,44VJ5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
EH2_k127_6945189_3	1123393.KB891317_gene2354	1.444e-21	99.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria,1KTEJ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
EH2_k127_6945189_0	159087.Daro_0574	1.093e-234	734.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KUGX@206389|Rhodocyclales	206389|Rhodocyclales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
EH2_k127_6945477_1	1123393.KB891316_gene1918	3.276e-91	309.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,2W16H@28216|Betaproteobacteria,1KSEG@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_6945477_0	1123393.KB891316_gene1917	1.353e-200	637.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,1KS3J@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
EH2_k127_6945477_2	1123073.KB899241_gene2778	4.056e-28	117.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1X6BT@135614|Xanthomonadales	135614|Xanthomonadales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
EH2_k127_6968626_3	1304872.JAGC01000009_gene578	7.496e-43	172.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,42Z1I@68525|delta/epsilon subdivisions,2WTPW@28221|Deltaproteobacteria,2M8FP@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
EH2_k127_6968626_1	404380.Gbem_1818	8.789e-100	327.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,43B30@68525|delta/epsilon subdivisions,2X6GS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
EH2_k127_6968626_4	443144.GM21_2432	7.611e-28	119.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase, TatD	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
EH2_k127_6968626_0	1317118.ATO8_16900	1.238e-163	518.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,2TUE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TatD related DNase	-	-	-	-	-	-	-	-	-	-	-	-	TatD_DNase
EH2_k127_6968626_2	864051.BurJ1DRAFT_1464	9.707e-74	258.0	28JEH@1|root,2Z98N@2|Bacteria,1RIK2@1224|Proteobacteria,2VWXE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7001734_1	261292.Nit79A3_3195	4.056e-213	679.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,3745T@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS_4,Response_reg
EH2_k127_7001734_0	292415.Tbd_1268	1.041e-220	715.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,1NWAF@1224|Proteobacteria,2WGYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
EH2_k127_7001734_3	85643.Tmz1t_3846	4.476e-48	178.0	COG0642@1|root,COG2205@2|Bacteria,1QVTG@1224|Proteobacteria,2WGU8@28216|Betaproteobacteria,2KZPM@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
EH2_k127_7001734_2	292415.Tbd_1266	7.059e-70	242.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
EH2_k127_7013948_2	1123393.KB891331_gene2964	2.943e-155	497.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,1KRI0@119069|Hydrogenophilales	119069|Hydrogenophilales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
EH2_k127_7013948_4	1123392.AQWL01000002_gene1858	1.325e-144	486.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,1KRZC@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mur ligase family, catalytic domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_7013948_3	1236959.BAMT01000002_gene2116	3.665e-147	490.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,2KMDD@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
EH2_k127_7013948_0	582744.Msip34_0454	7.161e-196	629.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,2KM24@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
EH2_k127_7013948_7	1163617.SCD_n02492	5.095e-23	103.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
EH2_k127_7013948_5	640081.Dsui_0245	2.162e-116	392.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,2KUQH@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
EH2_k127_7013948_6	1123393.KB891331_gene2970	8.471e-43	162.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,1KS2G@119069|Hydrogenophilales	119069|Hydrogenophilales	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
EH2_k127_7013948_1	1304883.KI912532_gene178	1.267e-158	511.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH2_k127_7031647_0	582744.Msip34_1299	5.417e-106	349.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,2KP5H@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
EH2_k127_7031647_1	1279015.KB908464_gene2117	4.996e-64	226.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,1Y4GK@135624|Aeromonadales	135624|Aeromonadales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
EH2_k127_7031647_4	1033802.SSPSH_001317	9.78e-26	118.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,1SEQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CbiX	cbiX	-	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
EH2_k127_7031647_2	522306.CAP2UW1_2961	3.719e-44	165.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2VW71@28216|Betaproteobacteria	28216|Betaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_7031647_3	768671.ThimaDRAFT_2301	2.276e-27	112.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S9TF@1236|Gammaproteobacteria,1X140@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
EH2_k127_7044496_0	1163617.SCD_n01695	3.612e-71	255.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria	28216|Betaproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
EH2_k127_7044496_1	1304883.KI912532_gene150	5.406e-56	206.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,2KW3R@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
EH2_k127_7044496_2	1121004.ATVC01000061_gene1546	4.361e-24	103.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,2KQ6S@206351|Neisseriales	206351|Neisseriales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
EH2_k127_7063013_4	1485544.JQKP01000001_gene1192	4.36e-90	316.0	2DQFH@1|root,336IU@2|Bacteria,1NE0H@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K20328	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
EH2_k127_7063013_0	1485544.JQKP01000001_gene1191	1.04e-256	805.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria	1224|Proteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	-	-	-	ko:K20327	ko02024,map02024	-	-	-	ko00000,ko00001,ko01003	-	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N
EH2_k127_7063013_5	1122180.Lokhon_01306	6.918e-32	145.0	28H81@1|root,2Z7K2@2|Bacteria,1NMZU@1224|Proteobacteria,2U5SR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial cellulose synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	BcsB
EH2_k127_7063013_6	314345.SPV1_08346	2.101e-19	102.0	COG3202@1|root,COG3202@2|Bacteria,1RCHN@1224|Proteobacteria	1224|Proteobacteria	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc4	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
EH2_k127_7063013_1	1198452.Jab_1c19330	1.067e-214	681.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,473TM@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	xanB	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
EH2_k127_7063013_2	1123393.KB891316_gene1084	2.868e-135	437.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,1KRNB@119069|Hydrogenophilales	119069|Hydrogenophilales	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
EH2_k127_7063013_3	292415.Tbd_1778	2.351e-96	318.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1KRMV@119069|Hydrogenophilales	119069|Hydrogenophilales	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
EH2_k127_7093484_14	1123392.AQWL01000004_gene2535	5.638e-58	203.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1KS6B@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
EH2_k127_7093484_10	1485544.JQKP01000007_gene1934	2.137e-80	271.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
EH2_k127_7093484_7	1144319.PMI16_00361	2.346e-113	370.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,4727W@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
EH2_k127_7093484_15	1163617.SCD_n01630	1.657e-54	203.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
EH2_k127_7093484_1	1288494.EBAPG3_760	1.981e-154	500.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,3723X@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
EH2_k127_7093484_2	265072.Mfla_1523	6.762e-131	434.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,2KKRG@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
EH2_k127_7093484_11	1163617.SCD_n01627	2.681e-73	252.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH2_k127_7093484_0	292415.Tbd_0793	8.725e-234	736.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,1KRHS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
EH2_k127_7093484_16	1163617.SCD_n01626	1.062e-52	191.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the skp family	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
EH2_k127_7093484_8	292415.Tbd_0795	8.185e-104	347.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,1KRZF@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
EH2_k127_7093484_13	580332.Slit_1640	1.267e-58	208.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,44VTF@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
EH2_k127_7093484_4	292415.Tbd_0797	1.539e-123	400.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1KRBA@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
EH2_k127_7093484_3	1163617.SCD_n01622	1.791e-125	413.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
EH2_k127_7093484_12	640081.Dsui_2680	3.387e-66	239.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,2KW1V@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
EH2_k127_7093484_5	1502770.JQMG01000001_gene1864	6.432e-122	396.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,2KKD9@206350|Nitrosomonadales	206350|Nitrosomonadales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
EH2_k127_7093484_6	1123393.KB891327_gene458	7.178e-121	394.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,1KR9R@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
EH2_k127_7093484_17	1523503.JPMY01000009_gene630	3.47e-51	191.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,1S8A4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7093484_9	1163617.SCD_n01616	1.871e-86	306.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_7093484_18	292415.Tbd_1228	6.742e-48	174.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KS5V@119069|Hydrogenophilales	119069|Hydrogenophilales	L	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
EH2_k127_7116904_1	1163617.SCD_n01819	4.572e-118	384.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	dctP	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
EH2_k127_7116904_3	1123393.KB891327_gene321	7.738e-11	74.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
EH2_k127_7116904_2	1236542.BALM01000001_gene233	2.635e-58	220.0	COG3409@1|root,COG3409@2|Bacteria,1N3E4@1224|Proteobacteria,1RZ2A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
EH2_k127_7116904_0	1163617.SCD_n01209	2.558e-262	812.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_7117488_2	1316936.K678_02885	8.832e-90	322.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2JPKF@204441|Rhodospirillales	204441|Rhodospirillales	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
EH2_k127_7117488_4	321846.PS417_04675	1.668e-35	152.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1S12M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
EH2_k127_7117488_1	640081.Dsui_0665	2.242e-181	577.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,2KUW9@206389|Rhodocyclales	206389|Rhodocyclales	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
EH2_k127_7117488_0	243365.CV_2758	2.707e-233	738.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KPUY@206351|Neisseriales	206351|Neisseriales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
EH2_k127_7117488_5	1123392.AQWL01000004_gene2613	6.155e-12	70.0	2AG0E@1|root,3164F@2|Bacteria,1PWU9@1224|Proteobacteria,2WCD2@28216|Betaproteobacteria,1KTG1@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7117488_3	1231185.BAMP01000002_gene4395	1.441e-65	228.0	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,2U5IG@28211|Alphaproteobacteria,43JQI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	3-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
EH2_k127_7145651_5	580332.Slit_0737	5.378e-16	79.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,44WBD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
EH2_k127_7145651_2	1304883.KI912532_gene1408	2.706e-102	338.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KUF5@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
EH2_k127_7145651_4	1123393.KB891316_gene1722	8.333e-36	139.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,1KT0G@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7145651_1	1163617.SCD_n02700	7.317e-202	638.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
EH2_k127_7145651_3	1485544.JQKP01000012_gene2146	1.514e-93	320.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,44VHE@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
EH2_k127_7145651_0	1123393.KB891316_gene1725	4.615e-209	656.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,1KS9H@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Metalloenzyme superfamily	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
EH2_k127_7191623_12	522306.CAP2UW1_2484	7.513e-21	96.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1RDHW@1224|Proteobacteria,2VRY7@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,Trypsin_2
EH2_k127_7191623_8	1123393.KB891333_gene2552	2.128e-58	213.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,1KRMY@119069|Hydrogenophilales	119069|Hydrogenophilales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
EH2_k127_7191623_11	243365.CV_2931	7.814e-31	129.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,2KRYY@206351|Neisseriales	206351|Neisseriales	T	Belongs to the BolA IbaG family	bolA	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
EH2_k127_7191623_10	1163617.SCD_n01473	2.459e-40	162.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM YCII-related	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
EH2_k127_7191623_7	292415.Tbd_1529	3.416e-71	246.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,1KRP3@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Intracellular septation protein A	-	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
EH2_k127_7191623_3	580332.Slit_1630	5.626e-95	320.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
EH2_k127_7191623_5	261292.Nit79A3_3414	2.972e-84	290.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,3729G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
EH2_k127_7191623_4	1163617.SCD_n01477	1.145e-85	289.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
EH2_k127_7191623_1	1163617.SCD_n01478	1.483e-224	699.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
EH2_k127_7191623_0	1001585.MDS_1261	0.0	1028.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1YE1W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338,ko:K08675	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03029	-	-	-	AAA,LON_substr_bdg,Lon_C
EH2_k127_7191623_9	1123487.KB892868_gene1149	1.235e-52	193.0	2C845@1|root,33NTC@2|Bacteria,1NPCK@1224|Proteobacteria,2W63X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7191623_2	404380.Gbem_1808	2.675e-148	476.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
EH2_k127_7191623_6	443144.GM21_2441	5.699e-79	269.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,43VMU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
EH2_k127_7213330_2	1267005.KB911261_gene2327	6.902e-07	57.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
EH2_k127_7213330_1	1437824.BN940_15521	1.974e-29	120.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,3T46K@506|Alcaligenaceae	28216|Betaproteobacteria	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
EH2_k127_7213330_0	292415.Tbd_2079	9.766e-71	244.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,1KRGA@119069|Hydrogenophilales	119069|Hydrogenophilales	U	SecD export protein N-terminal TM region	-	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
EH2_k127_7223611_1	666681.M301_0691	1.934e-100	334.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2VQR0@28216|Betaproteobacteria,2KMIY@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
EH2_k127_7223611_0	395494.Galf_0005	5.909e-157	502.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2VJZM@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
EH2_k127_7223611_2	1502770.JQMG01000001_gene82	7.923e-28	113.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,2KM2P@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
EH2_k127_7238325_0	1485544.JQKP01000007_gene1962	1.697e-164	520.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,44VDK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
EH2_k127_7238325_1	1123392.AQWL01000005_gene3090	1.822e-113	384.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2WGUD@28216|Betaproteobacteria,1KSJ4@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
EH2_k127_7238325_2	1123392.AQWL01000005_gene3091	3.411e-68	234.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,1KS4W@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
EH2_k127_7253611_1	1123392.AQWL01000005_gene2889	4.34e-62	216.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria,1KRPT@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
EH2_k127_7253611_0	292415.Tbd_2148	3.578e-195	617.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1KRIB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
EH2_k127_7253611_2	742823.HMPREF9465_01733	1.023e-05	57.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,4PR2B@995019|Sutterellaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF615)	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
EH2_k127_7256333_0	1123393.KB891328_gene686	4.101e-238	739.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KRDD@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
EH2_k127_7256333_3	1123392.AQWL01000004_gene2651	5.117e-97	320.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KRFX@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
EH2_k127_7256333_4	292415.Tbd_0641	5.386e-11	65.0	COG4736@1|root,COG4736@2|Bacteria,1PWVN@1224|Proteobacteria,2WCEC@28216|Betaproteobacteria,1KTI8@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cbb3-type cytochrome oxidase component FixQ	-	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
EH2_k127_7256333_2	1123392.AQWL01000004_gene2653	1.488e-102	343.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KRIX@119069|Hydrogenophilales	119069|Hydrogenophilales	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
EH2_k127_7256333_1	1123392.AQWL01000004_gene2654	2.392e-200	633.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KS0U@119069|Hydrogenophilales	119069|Hydrogenophilales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
EH2_k127_728105_1	396588.Tgr7_2031	2.522e-85	289.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1WVZF@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
EH2_k127_728105_0	1123368.AUIS01000005_gene487	4.097e-160	509.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RYC8@1236|Gammaproteobacteria,2NC3Q@225057|Acidithiobacillales	225057|Acidithiobacillales	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
EH2_k127_7306767_3	640510.BC1001_1378	2.464e-48	175.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,1K1RS@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
EH2_k127_7306767_1	1304883.KI912532_gene2	2.844e-52	194.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,2VPPP@28216|Betaproteobacteria,2KVX9@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
EH2_k127_7306767_0	292415.Tbd_1258	6.584e-100	335.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,1KS8U@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_7306767_5	1123392.AQWL01000004_gene2778	8.059e-13	70.0	2EITT@1|root,3163R@2|Bacteria,1PWSX@1224|Proteobacteria,2WCBQ@28216|Betaproteobacteria,1KTDU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
EH2_k127_7306767_4	105559.Nwat_0850	1.257e-18	90.0	COG1873@1|root,COG1873@2|Bacteria,1QW30@1224|Proteobacteria	1224|Proteobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
EH2_k127_7306767_2	1120985.AUMI01000017_gene2729	1.776e-48	181.0	COG2930@1|root,COG2930@2|Bacteria,1VBSP@1239|Firmicutes,4H54G@909932|Negativicutes	909932|Negativicutes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
EH2_k127_731538_0	1122236.KB905141_gene1679	5.546e-164	522.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,2KKUT@206350|Nitrosomonadales	206350|Nitrosomonadales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
EH2_k127_731538_3	640081.Dsui_0164	2.787e-39	147.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,2KX43@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
EH2_k127_731538_2	1163617.SCD_n02106	4.966e-44	162.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
EH2_k127_731538_1	1123487.KB892857_gene2268	8.281e-57	211.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,2KW6F@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
EH2_k127_731538_4	1236959.BAMT01000006_gene404	1.278e-13	78.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,2KN10@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
EH2_k127_7338735_2	1123393.KB891330_gene887	6.319e-74	251.0	COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,2WE7F@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
EH2_k127_7338735_0	159087.Daro_0072	1.296e-130	421.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,2WA7Z@28216|Betaproteobacteria,2KYR5@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
EH2_k127_7338735_1	1538295.JY96_19665	5.906e-117	382.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2VMBK@28216|Betaproteobacteria,1KJP7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
EH2_k127_7358267_1	1033802.SSPSH_000502	5.21e-166	555.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
EH2_k127_7358267_3	1123393.KB891329_gene998	2.474e-140	471.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,1KSH7@119069|Hydrogenophilales	119069|Hydrogenophilales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
EH2_k127_7358267_2	1485544.JQKP01000010_gene838	2.647e-151	484.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,44VB3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
EH2_k127_7358267_0	1123392.AQWL01000008_gene1176	4.713e-291	918.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KS7S@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
EH2_k127_7358267_4	292415.Tbd_0607	2.836e-87	290.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,1KRBE@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
EH2_k127_7359212_0	864051.BurJ1DRAFT_1466	1.234e-110	368.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1KK62@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	futA1	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
EH2_k127_7359212_1	1110502.TMO_1534	8.272e-38	158.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,2JPDF@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1178 ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
EH2_k127_7363758_1	748247.AZKH_0279	7.745e-138	446.0	COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,2VPY4@28216|Betaproteobacteria,2KVED@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
EH2_k127_7363758_7	1123392.AQWL01000002_gene1903	4.01e-38	149.0	COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2VV8B@28216|Betaproteobacteria,1KT2D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
EH2_k127_7363758_0	85643.Tmz1t_3537	5.605e-206	677.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria,2KXTR@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
EH2_k127_7363758_12	1144319.PMI16_03594	7.511e-08	62.0	COG2867@1|root,COG2867@2|Bacteria,1QUZA@1224|Proteobacteria,2VUHS@28216|Betaproteobacteria,4750S@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH2_k127_7363758_11	688245.CtCNB1_2372	1.113e-13	78.0	COG2867@1|root,COG2867@2|Bacteria,1R01P@1224|Proteobacteria,2WHS4@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH2_k127_7363758_8	1123354.AUDR01000018_gene1123	8.36e-23	104.0	2E6EI@1|root,33120@2|Bacteria,1NA6C@1224|Proteobacteria,2VW1M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7363758_3	1123392.AQWL01000018_gene78	3.827e-105	356.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,1KSM5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
EH2_k127_7363758_2	1123367.C666_12820	5.854e-128	420.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,2KUFP@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
EH2_k127_7363758_4	640081.Dsui_0993	1.661e-80	281.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
EH2_k127_7363758_6	522306.CAP2UW1_4050	2.043e-53	196.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,1KQYS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
EH2_k127_7363758_10	1000565.METUNv1_03287	3.282e-14	82.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria,2KWYI@206389|Rhodocyclales	206389|Rhodocyclales	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
EH2_k127_7363758_5	1175306.GWL_32920	4.3e-62	216.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,47677@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
EH2_k127_7369150_3	545264.KB898747_gene429	1.57e-29	118.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,1RRX7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	permease	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
EH2_k127_7369150_2	545264.KB898747_gene430	1.812e-31	129.0	COG0347@1|root,COG0347@2|Bacteria,1MZ43@1224|Proteobacteria	1224|Proteobacteria	E	nitrogen regulatory protein PII	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7369150_0	1122614.JHZF01000013_gene3463	7.194e-122	410.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
EH2_k127_7369150_1	1454004.AW11_00852	1.01e-66	231.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
EH2_k127_7376083_1	1163617.SCD_n01050	7.767e-193	609.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
EH2_k127_7376083_3	748247.AZKH_1172	6.679e-33	132.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
EH2_k127_7376083_2	1163617.SCD_n02464	3.287e-146	474.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	CBS domain containing protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
EH2_k127_7376083_0	1123393.KB891316_gene1696	3.632e-214	677.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KRC1@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
EH2_k127_744870_1	1123393.KB891327_gene266	7.176e-147	494.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,1KRIY@119069|Hydrogenophilales	119069|Hydrogenophilales	E	AIR synthase related protein, N-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
EH2_k127_744870_0	1123392.AQWL01000006_gene669	1.004e-148	486.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KRJE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
EH2_k127_744870_2	1123392.AQWL01000005_gene3195	6.405e-11	64.0	COG1977@1|root,COG1977@2|Bacteria,1PWRM@1224|Proteobacteria,2WCAB@28216|Betaproteobacteria,1KTBD@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
EH2_k127_7448814_0	292415.Tbd_2624	3.781e-211	656.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
EH2_k127_7448814_1	1123392.AQWL01000006_gene622	4.713e-150	480.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KS2E@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
EH2_k127_7448814_3	76114.ebA3508	5.152e-92	308.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VP8T@28216|Betaproteobacteria,2KUS8@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
EH2_k127_7448814_2	305700.B447_02051	5.308e-148	483.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KUGD@206389|Rhodocyclales	206389|Rhodocyclales	T	COG3850 Signal transduction histidine kinase, nitrate nitrite-specific	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
EH2_k127_7478404_0	1304883.KI912532_gene2521	5.39e-146	469.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
EH2_k127_7478404_7	1123392.AQWL01000008_gene1261	7.383e-13	74.0	29460@1|root,2ZRKG@2|Bacteria,1PBM2@1224|Proteobacteria,2W5WD@28216|Betaproteobacteria,1KTE9@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	-
EH2_k127_7478404_6	1304883.KI912532_gene2523	1.025e-36	144.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,2KWYW@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
EH2_k127_7478404_3	1123393.KB891329_gene932	1.026e-48	178.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,1KRPN@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
EH2_k127_7478404_2	1000565.METUNv1_00407	3.181e-75	254.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,2KWDY@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
EH2_k127_7478404_1	292415.Tbd_1757	9.87e-128	418.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,1KSVD@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
EH2_k127_7478404_4	1288494.EBAPG3_10630	3.903e-47	174.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,2VUK7@28216|Betaproteobacteria,3733G@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
EH2_k127_7478404_5	1123393.KB891329_gene1059	2.926e-41	158.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,1KSVF@119069|Hydrogenophilales	119069|Hydrogenophilales	J	LigT like Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	LigT_PEase
EH2_k127_7483312_2	292415.Tbd_1139	4.089e-41	155.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KSBR@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
EH2_k127_7483312_1	1123393.KB891327_gene372	1.258e-137	442.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KRK6@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH2_k127_7483312_0	292415.Tbd_1137	4.157e-167	530.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KS4M@119069|Hydrogenophilales	119069|Hydrogenophilales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
EH2_k127_7490749_3	296591.Bpro_2589	1.343e-47	174.0	COG2890@1|root,COG2890@2|Bacteria,1QYJ3@1224|Proteobacteria,2WHFP@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
EH2_k127_7490749_4	1000565.METUNv1_03041	4.86e-37	143.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,2KWYD@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
EH2_k127_7490749_5	497321.C664_03550	6.786e-31	126.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VV0X@28216|Betaproteobacteria,2KZUI@206389|Rhodocyclales	206389|Rhodocyclales	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
EH2_k127_7490749_1	396588.Tgr7_2589	5.545e-255	805.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
EH2_k127_7490749_7	396588.Tgr7_2590	3.799e-20	100.0	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
EH2_k127_7490749_2	396588.Tgr7_2590	5.338e-133	436.0	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
EH2_k127_7490749_0	1123393.KB891317_gene2196	7.946e-257	802.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,1KSF8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP
EH2_k127_7490749_6	1123393.KB891328_gene696	3.656e-30	120.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,1KT8R@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH2_k127_749829_3	1123392.AQWL01000005_gene2967	8.693e-55	196.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,1KT3H@119069|Hydrogenophilales	119069|Hydrogenophilales	P	ApaG domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF525
EH2_k127_749829_1	1163617.SCD_n02535	1.926e-126	418.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
EH2_k127_749829_2	1123393.KB891316_gene1546	8.847e-104	341.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1KRSC@119069|Hydrogenophilales	119069|Hydrogenophilales	G	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
EH2_k127_749829_0	1123393.KB891316_gene1545	7.959e-162	517.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,1KS54@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
EH2_k127_7542534_1	640081.Dsui_1710	2.164e-143	475.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH2_k127_7542534_2	228410.NE1865	3.102e-65	226.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,3734B@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	PFAM CheW-like protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
EH2_k127_7542534_0	1485544.JQKP01000011_gene701	2.577e-240	766.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,44W69@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transducing histidine kinase homodimeric	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
EH2_k127_7542534_3	159087.Daro_0725	1.066e-60	211.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KWAN@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
EH2_k127_7542534_4	640081.Dsui_1706	3.923e-57	217.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,2VNG3@28216|Betaproteobacteria,2KVTI@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
EH2_k127_7542534_5	640081.Dsui_0118	1.005e-34	133.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,2KWQF@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
EH2_k127_7548097_0	1000565.METUNv1_00215	3.567e-186	583.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,2KUGC@206389|Rhodocyclales	206389|Rhodocyclales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
EH2_k127_7585008_3	1430440.MGMSRv2_0081	3.151e-51	191.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1MXA3@1224|Proteobacteria,2TQV6@28211|Alphaproteobacteria,2JV72@204441|Rhodospirillales	204441|Rhodospirillales	PT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,NMT1
EH2_k127_7585008_0	1158292.JPOE01000002_gene1854	0.0	1120.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
EH2_k127_7585008_2	1123393.KB891326_gene75	1.396e-70	247.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Nicotinamidase	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
EH2_k127_7585008_1	338969.Rfer_0827	3.332e-162	525.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
EH2_k127_7599159_1	582744.Msip34_0458	1.491e-66	235.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,2KM82@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	-	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_M
EH2_k127_7599159_0	1123393.KB891331_gene2962	3.761e-104	351.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,1KS5G@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
EH2_k127_7616768_2	1266925.JHVX01000002_gene1068	4.569e-86	293.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,372MP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
EH2_k127_7616768_1	1123393.KB891316_gene2101	9.201e-127	410.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,1KR9U@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Transporter associated domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
EH2_k127_7616768_4	261292.Nit79A3_0199	2.61e-40	155.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,3735J@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
EH2_k127_7616768_0	1101195.Meth11DRAFT_2212	5.054e-135	445.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,2KM1T@206350|Nitrosomonadales	206350|Nitrosomonadales	T	AAA domain	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
EH2_k127_7616768_3	640081.Dsui_1194	1.03e-71	247.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,2KU9F@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
EH2_k127_7738888_5	265072.Mfla_0735	2.475e-39	149.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,2KM4Y@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
EH2_k127_7738888_3	1123392.AQWL01000002_gene2113	4.163e-55	198.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,1KRP7@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
EH2_k127_7738888_2	228410.NE0968	2.452e-63	221.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,37305@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
EH2_k127_7738888_4	1123392.AQWL01000002_gene2115	3.254e-43	158.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,1KRT0@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
EH2_k127_7738888_0	582744.Msip34_1996	3.976e-247	779.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KKJN@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
EH2_k127_7738888_1	1163617.SCD_n02630	1.198e-82	280.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
EH2_k127_7750365_0	1123393.KB891316_gene2100	2.626e-91	318.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KSQG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
EH2_k127_7750365_1	1348657.M622_00690	9.809e-21	104.0	COG0492@1|root,COG0492@2|Bacteria,1RKSQ@1224|Proteobacteria,2WBPB@28216|Betaproteobacteria,2KYR0@206389|Rhodocyclales	206389|Rhodocyclales	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
EH2_k127_7753562_2	1123392.AQWL01000004_gene2493	7.979e-39	149.0	29C3U@1|root,2ZZ29@2|Bacteria,1RFDP@1224|Proteobacteria,2VS91@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7753562_1	768671.ThimaDRAFT_1865	4.321e-64	226.0	2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria,1SRBB@1236|Gammaproteobacteria,1X1A2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7753562_0	768671.ThimaDRAFT_1866	3.08e-65	228.0	COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,1X0YX@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
EH2_k127_7753562_3	1123393.KB891316_gene1118	4.324e-23	106.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2W1SC@28216|Betaproteobacteria,1KSI9@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
EH2_k127_7758294_5	85643.Tmz1t_1472	8.624e-29	121.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2VKGU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
EH2_k127_7758294_4	85643.Tmz1t_1471	2.512e-66	232.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VRAN@28216|Betaproteobacteria,2KXE9@206389|Rhodocyclales	206389|Rhodocyclales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
EH2_k127_7758294_6	572477.Alvin_1300	2.129e-25	109.0	2EE2B@1|root,32X3W@2|Bacteria,1N4QZ@1224|Proteobacteria,1SB3P@1236|Gammaproteobacteria,1WZ1S@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7758294_1	765911.Thivi_2824	8.031e-108	359.0	COG5380@1|root,COG5380@2|Bacteria,1N6UY@1224|Proteobacteria,1S03R@1236|Gammaproteobacteria,1WX19@135613|Chromatiales	135613|Chromatiales	O	lipid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7758294_7	195250.CM001776_gene743	3.269e-16	88.0	COG1226@1|root,32Y28@2|Bacteria,1G7VB@1117|Cyanobacteria,1H1NC@1129|Synechococcus	1117|Cyanobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
EH2_k127_7758294_3	1304885.AUEY01000011_gene1728	8.765e-89	309.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QYY@68525|delta/epsilon subdivisions,2WNXG@28221|Deltaproteobacteria,2MNAV@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
EH2_k127_7758294_2	1210884.HG799469_gene14130	1.573e-93	313.0	COG1611@1|root,COG1611@2|Bacteria,2J21H@203682|Planctomycetes	203682|Planctomycetes	S	Possible lysine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
EH2_k127_7758294_0	768671.ThimaDRAFT_1323	3.025e-123	400.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXCM@135613|Chromatiales	135613|Chromatiales	S	PFAM Polyphosphate kinase 2	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
EH2_k127_7787585_2	1538295.JY96_19665	1.474e-117	379.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2VMBK@28216|Betaproteobacteria,1KJP7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
EH2_k127_7787585_0	1123393.KB891330_gene884	0.0	1718.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,2WGI2@28216|Betaproteobacteria	28216|Betaproteobacteria	EI	urea carboxylase	uca	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
EH2_k127_7787585_1	1123393.KB891330_gene883	2.983e-177	584.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KSIC@119069|Hydrogenophilales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
EH2_k127_7793116_3	338966.Ppro_0084	3.531e-70	267.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43T8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
EH2_k127_7793116_1	1255043.TVNIR_1979	4.956e-79	282.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
EH2_k127_7793116_2	1123393.KB891316_gene1130	2.633e-72	249.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,1KSJC@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
EH2_k127_7793116_4	1008459.TASI_0975	1.33e-21	100.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,3T4SK@506|Alcaligenaceae	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
EH2_k127_7793116_0	1163617.SCD_n00511	4.243e-292	915.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_7814954_3	1437824.BN940_16166	2.956e-13	71.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,3T2W1@506|Alcaligenaceae	28216|Betaproteobacteria	G	C4-dicarboxylate ABC transporter	dctP	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
EH2_k127_7814954_0	153948.NAL212_0715	4.497e-99	337.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,3723W@32003|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like)	-	-	-	-	-	-	-	-	-	-	-	-	HAD
EH2_k127_7814954_1	1163617.SCD_n02226	1.991e-57	207.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
EH2_k127_7814954_2	1000565.METUNv1_01638	1.468e-50	188.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria,2KWFR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7834036_0	864051.BurJ1DRAFT_1480	5.28e-170	543.0	COG0502@1|root,COG0502@2|Bacteria,1QWVD@1224|Proteobacteria,2WH18@28216|Betaproteobacteria,1KMSG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
EH2_k127_7834325_1	1123393.KB891333_gene2641	4.467e-149	477.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH2_k127_7834325_0	1123392.AQWL01000007_gene878	1.591e-202	638.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
EH2_k127_7834325_2	292415.Tbd_1581	1.273e-35	140.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KSR8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
EH2_k127_7852654_2	595494.Tola_1997	6.393e-32	126.0	COG1553@1|root,COG1553@2|Bacteria,1RJB0@1224|Proteobacteria,1SC2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
EH2_k127_7852654_3	497321.C664_15858	4.741e-08	59.0	COG4531@1|root,COG4531@2|Bacteria,1N099@1224|Proteobacteria,2VX99@28216|Betaproteobacteria,2KZGG@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function (DUF2796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2796
EH2_k127_7852654_1	1454004.AW11_02403	6.123e-82	279.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2VQ4I@28216|Betaproteobacteria,1KQWQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
EH2_k127_7852654_0	522306.CAP2UW1_4085	3.049e-131	425.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,2VJWZ@28216|Betaproteobacteria,1KQN6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
EH2_k127_7866089_6	1123393.KB891316_gene1588	4.306e-41	151.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,1KSRT@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
EH2_k127_7866089_4	1123392.AQWL01000005_gene3005	2.165e-133	431.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,1KSQE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
EH2_k127_7866089_5	40373.F991_00375	5.094e-95	328.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,3NT1J@468|Moraxellaceae	1236|Gammaproteobacteria	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	nasD	-	-	ko:K02049,ko:K15578	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17	-	-	ABC_tran
EH2_k127_7866089_3	1101195.Meth11DRAFT_0419	8.134e-145	482.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,2KKIU@206350|Nitrosomonadales	206350|Nitrosomonadales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
EH2_k127_7866089_2	292415.Tbd_2456	8.084e-171	541.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1KRF9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
EH2_k127_7866089_7	1163617.SCD_n00039	8.876e-29	117.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria	28216|Betaproteobacteria	KL	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
EH2_k127_7866089_0	1123393.KB891316_gene1804	1.274e-291	901.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1KRCP@119069|Hydrogenophilales	119069|Hydrogenophilales	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
EH2_k127_7866089_1	1123392.AQWL01000005_gene3205	8.758e-207	651.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,1KS4T@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Phosphoribosylglycinamide synthetase, C domain	-	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
EH2_k127_7866089_8	580332.Slit_0295	2.401e-20	94.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,44VTE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
EH2_k127_7873461_4	1454004.AW11_03033	1.35e-60	215.0	COG4943@1|root,COG4943@2|Bacteria,1REXW@1224|Proteobacteria,2W323@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
EH2_k127_7873461_3	1123393.KB891317_gene2339	3.136e-76	259.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,1KSGR@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Peptide methionine sulfoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	PMSR
EH2_k127_7873461_2	1307759.JOMJ01000003_gene743	8.104e-109	368.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,43AMJ@68525|delta/epsilon subdivisions,2X61J@28221|Deltaproteobacteria,2M8KF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
EH2_k127_7873461_0	76114.ebA5427	2.831e-160	520.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,2KUN7@206389|Rhodocyclales	206389|Rhodocyclales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
EH2_k127_7873461_6	1123393.KB891317_gene2444	2.755e-31	130.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,1KRU2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Invasion gene expression up-regulator, SirB	-	-	-	-	-	-	-	-	-	-	-	-	SirB
EH2_k127_7873461_9	1121035.AUCH01000015_gene2581	3.091e-08	59.0	2EA8Z@1|root,334DE@2|Bacteria,1NDKW@1224|Proteobacteria,2VVWJ@28216|Betaproteobacteria,2KXKV@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7873461_5	1163617.SCD_n01941	1.75e-45	168.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
EH2_k127_7873461_7	509190.Cseg_3398	5.29e-30	135.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
EH2_k127_7873461_1	1123393.KB891316_gene1585	2.704e-126	408.0	COG0412@1|root,COG0412@2|Bacteria,1PDE6@1224|Proteobacteria,2VQWV@28216|Betaproteobacteria,1KSV3@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
EH2_k127_7873461_8	686340.Metal_2418	5.867e-09	56.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S4VI@1236|Gammaproteobacteria,1XF76@135618|Methylococcales	135618|Methylococcales	O	PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
EH2_k127_78874_4	1095769.CAHF01000008_gene3595	1.036e-86	291.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,4723N@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
EH2_k127_78874_9	292415.Tbd_0699	5.265e-52	188.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,1KRSB@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RimP C-terminal SH3 domain	-	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
EH2_k127_78874_10	1163617.SCD_n02644	1.019e-43	169.0	COG5456@1|root,COG5456@2|Bacteria,1N6AR@1224|Proteobacteria,2VU84@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
EH2_k127_78874_1	292415.Tbd_0342	1.367e-198	629.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KSAC@119069|Hydrogenophilales	119069|Hydrogenophilales	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
EH2_k127_78874_2	1123393.KB891330_gene758	2.719e-138	445.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KSC5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixP_N
EH2_k127_78874_11	1123393.KB891330_gene759	1.309e-17	85.0	2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,2VXSI@28216|Betaproteobacteria,1KTEY@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
EH2_k127_78874_3	292415.Tbd_0339	3.319e-125	404.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KRX9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
EH2_k127_78874_0	292415.Tbd_0338	9.605e-277	856.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KSCE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
EH2_k127_78874_8	748280.NH8B_3836	3.682e-59	210.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,2KQCS@206351|Neisseriales	206351|Neisseriales	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
EH2_k127_78874_6	292415.Tbd_0336	3.366e-64	223.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria,1KSDE@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
EH2_k127_78874_5	1038869.AXAN01000007_gene5769	1.791e-64	235.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,1K4CH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
EH2_k127_78874_7	1121004.ATVC01000071_gene1165	1.836e-59	209.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales	206351|Neisseriales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
EH2_k127_7897979_0	159087.Daro_0729	1.859e-226	723.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH2_k127_7897979_1	1121035.AUCH01000039_gene1728	2.794e-66	234.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
EH2_k127_7921706_4	580332.Slit_1618	6.425e-35	138.0	2AB8D@1|root,310NU@2|Bacteria,1RFGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7921706_0	1123392.AQWL01000003_gene141	1.366e-244	759.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
EH2_k127_7921706_2	1123392.AQWL01000003_gene142	4.412e-117	379.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria,1KSBB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_7921706_1	1123393.KB891326_gene133	3.38e-201	630.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,1KRZI@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
EH2_k127_7921706_3	1123393.KB891326_gene132	2.528e-48	176.0	COG1773@1|root,COG1773@2|Bacteria,1MV2U@1224|Proteobacteria,2VKNQ@28216|Betaproteobacteria,1KT15@119069|Hydrogenophilales	119069|Hydrogenophilales	C	HupH hydrogenase expression protein, C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HupH_C
EH2_k127_7921706_5	1123393.KB891326_gene131	1.147e-23	100.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria,1KT05@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
EH2_k127_7921862_4	292415.Tbd_2606	3.868e-13	70.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
EH2_k127_7921862_1	292415.Tbd_0769	4.423e-70	247.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,1KSWG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
EH2_k127_7921862_0	522306.CAP2UW1_3680	9.036e-123	402.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KQCV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_7921862_2	1123261.AXDW01000010_gene339	1.692e-31	137.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
EH2_k127_794496_5	342113.DM82_6012	2.191e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VKH2@28216|Betaproteobacteria,1K6NX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
EH2_k127_794496_3	626887.J057_16215	2.089e-33	138.0	COG0515@1|root,COG2020@1|root,COG0515@2|Bacteria,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
EH2_k127_794496_1	742823.HMPREF9465_00478	1.292e-63	227.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,2W05P@28216|Betaproteobacteria,4PQYC@995019|Sutterellaceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_794496_0	1163617.SCD_n00464	1.495e-72	259.0	28Q1D@1|root,2ZCJS@2|Bacteria,1RF11@1224|Proteobacteria,2VQZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_794496_2	1288494.EBAPG3_14930	3.713e-55	199.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,2VSUS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
EH2_k127_794496_4	1123487.KB892846_gene512	4.316e-19	90.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
EH2_k127_7946159_1	760117.JN27_21965	6.851e-124	402.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2VIB9@28216|Betaproteobacteria,475TD@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
EH2_k127_7946159_0	1163617.SCD_n02956	6.515e-156	508.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
EH2_k127_7946159_2	29581.BW37_01049	4.811e-06	54.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,473D4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
EH2_k127_7969691_1	1439940.BAY1663_02832	8.272e-72	246.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
EH2_k127_7969691_0	1163617.SCD_n01470	0.0	1144.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
EH2_k127_7980286_2	1304883.KI912532_gene826	9.754e-22	95.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KUBX@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
EH2_k127_7980286_0	292415.Tbd_2824	2.043e-193	612.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,1KRHC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	MnmE helical domain	-	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
EH2_k127_7980286_3	1132855.KB913035_gene2367	1.739e-08	64.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VTG4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Ankyrin	tnkS	-	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_3,Ank_4
EH2_k127_7980286_1	1123392.AQWL01000013_gene2364	5.468e-62	218.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,2VPN4@28216|Betaproteobacteria,1KSBJ@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
EH2_k127_7991912_0	1121861.KB899911_gene1186	3.302e-138	476.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	28211|Alphaproteobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
EH2_k127_7991912_1	1150469.RSPPHO_01171	4.317e-40	162.0	COG4122@1|root,COG4122@2|Bacteria,1MYYK@1224|Proteobacteria,2UADT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
EH2_k127_8004360_0	1304883.KI912532_gene1377	2.563e-126	407.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KUGX@206389|Rhodocyclales	206389|Rhodocyclales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
EH2_k127_8004360_1	1266925.JHVX01000022_gene1763	4.236e-103	344.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
EH2_k127_8020711_4	1123393.KB891331_gene2890	5.716e-22	96.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,1KRVB@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
EH2_k127_8020711_1	1123392.AQWL01000002_gene1930	1.352e-205	648.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,1KSW6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	-	-	-	-	-	-	-	-	-	-	GDC-P
EH2_k127_8020711_2	1163617.SCD_n02779	6.581e-72	247.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
EH2_k127_8020711_0	1123393.KB891331_gene2894	3.946e-264	819.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,1KSAV@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
EH2_k127_8020711_3	1121035.AUCH01000002_gene1549	1.372e-41	155.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
EH2_k127_8025326_1	1123393.KB891316_gene1858	2.266e-121	395.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,1KR9Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
EH2_k127_8025326_0	402626.Rpic_3146	3.223e-179	566.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1K2D1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
EH2_k127_8025326_2	292415.Tbd_2494	7.458e-90	305.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,1KRJN@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
EH2_k127_8036356_0	1123392.AQWL01000003_gene277	2.135e-51	185.0	COG0778@1|root,COG0778@2|Bacteria,1Q0ZY@1224|Proteobacteria,2WAFT@28216|Betaproteobacteria,1KSUE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
EH2_k127_8036983_1	1123392.AQWL01000006_gene636	7.1e-108	356.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
EH2_k127_8036983_4	62928.azo0293	6.674e-05	53.0	COG0716@1|root,COG0716@2|Bacteria,1N2QA@1224|Proteobacteria,2VJPN@28216|Betaproteobacteria,2KVMA@206389|Rhodocyclales	206389|Rhodocyclales	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_8036983_0	535289.Dtpsy_0106	0.0	1219.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,2VJYM@28216|Betaproteobacteria,4ABIQ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
EH2_k127_8036983_3	1123367.C666_09125	3.166e-20	92.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
EH2_k127_8036983_2	1276756.AUEX01000002_gene442	1.206e-66	231.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VQMN@28216|Betaproteobacteria,4ADP9@80864|Comamonadaceae	28216|Betaproteobacteria	O	anaerobic ribonucleoside-triphosphate reductase activating protein	nrdG	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
EH2_k127_8056048_2	1163617.SCD_n01735	9.502e-28	116.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
EH2_k127_8056048_0	857087.Metme_0874	1.952e-160	530.0	COG3291@1|root,COG3291@2|Bacteria,1RGWM@1224|Proteobacteria,1THXR@1236|Gammaproteobacteria,1XFZT@135618|Methylococcales	135618|Methylococcales	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
EH2_k127_8056048_1	1454004.AW11_00842	3.288e-151	492.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,1KQ60@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
EH2_k127_808528_2	1049564.TevJSym_aj00790	3.05e-15	76.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,1RS3Q@1236|Gammaproteobacteria,1JB7K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
EH2_k127_808528_1	1163617.SCD_n01210	1.942e-137	440.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
EH2_k127_808528_0	1163617.SCD_n01209	0.0	1057.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
EH2_k127_8089241_1	1123368.AUIS01000001_gene1993	5.542e-61	231.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
EH2_k127_8089241_0	1123368.AUIS01000019_gene1227	2.147e-116	381.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	apc3	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
EH2_k127_8119293_5	1163617.SCD_n01727	2.461e-17	81.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
EH2_k127_8119293_2	292415.Tbd_0871	3.063e-142	457.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,2W1RG@28216|Betaproteobacteria,1KS0P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
EH2_k127_8119293_6	1123368.AUIS01000001_gene1863	3.75e-06	55.0	2EIBB@1|root,33C2R@2|Bacteria,1PS8K@1224|Proteobacteria,1ST8B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_8119293_1	292415.Tbd_0869	4.776e-148	471.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
EH2_k127_8119293_4	511.JT27_04385	2.958e-21	106.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,3T2GI@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG3245 Cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
EH2_k127_8119293_0	1123392.AQWL01000009_gene1121	1.643e-312	971.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria,1KSRU@119069|Hydrogenophilales	119069|Hydrogenophilales	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
EH2_k127_8119293_3	1123392.AQWL01000009_gene1122	7.3e-26	109.0	COG3448@1|root,COG3448@2|Bacteria,1PWS1@1224|Proteobacteria,2WCAV@28216|Betaproteobacteria,1KTC8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_8124335_1	1163617.SCD_n01767	7.805e-118	398.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
EH2_k127_8124335_0	1163617.SCD_n01159	1.377e-120	391.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
EH2_k127_8124335_2	1123392.AQWL01000003_gene417	8.126e-65	227.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2WGE2@28216|Betaproteobacteria,1KSQD@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
EH2_k127_8124335_3	1038867.AXAY01000014_gene5209	0.0008835	45.0	COG0021@1|root,COG0176@1|root,COG0021@2|Bacteria,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,2TZC4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
EH2_k127_8129797_1	335283.Neut_0860	3.792e-183	593.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,371W3@32003|Nitrosomonadales	28216|Betaproteobacteria	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
EH2_k127_8129797_0	265072.Mfla_0061	7.61e-224	700.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KM12@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
EH2_k127_8129797_2	580332.Slit_1837	5.708e-10	62.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,44W4H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
EH2_k127_8153497_1	497321.C664_10737	1.312e-100	336.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,2KV8G@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
EH2_k127_8153497_0	292415.Tbd_0809	9.247e-106	349.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KREX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
EH2_k127_8153497_2	395494.Galf_0306	6.085e-50	185.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,44W7H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
EH2_k127_8165962_1	929562.Emtol_0826	1.697e-81	282.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
EH2_k127_8165962_2	522306.CAP2UW1_1027	1.264e-37	155.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
EH2_k127_8165962_0	381666.H16_A2342	6.677e-229	729.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,1K087@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Atp-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
EH2_k127_8201561_0	316058.RPB_4106	2.122e-60	221.0	COG2357@1|root,COG2357@2|Bacteria,1QYWE@1224|Proteobacteria	1224|Proteobacteria	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_8201561_1	1485544.JQKP01000003_gene272	7.922e-15	87.0	28V1B@1|root,2ZH4V@2|Bacteria,1PBEX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_820956_2	543728.Vapar_4141	1.675e-13	72.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,4A9KV@80864|Comamonadaceae	28216|Betaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
EH2_k127_820956_1	1163617.SCD_n01262	1.592e-115	383.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
EH2_k127_820956_0	497321.C664_18579	3.017e-279	863.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
EH2_k127_844416_0	292415.Tbd_0693	0.0	1143.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,1KS6C@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
EH2_k127_844416_2	1123392.AQWL01000004_gene2594	9.711e-51	195.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,2VU2H@28216|Betaproteobacteria,1KS4N@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_844416_1	1163617.SCD_n01708	2.194e-104	343.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
EH2_k127_904124_2	1123393.KB891318_gene2162	7.359e-73	253.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,1KSS4@119069|Hydrogenophilales	119069|Hydrogenophilales	G	MOFRL family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4147,MOFRL
EH2_k127_904124_0	1123487.KB892857_gene2452	2.42e-200	644.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	rpfC	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
EH2_k127_904124_1	1123487.KB892857_gene2451	2.297e-154	499.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,2VK22@28216|Betaproteobacteria,2KW00@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
EH2_k127_914265_3	292415.Tbd_2050	1.388e-72	250.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,1KSBC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
EH2_k127_914265_2	522306.CAP2UW1_0390	3.059e-82	279.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,1KQS6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
EH2_k127_914265_4	292415.Tbd_1509	4.111e-44	164.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,1KT4N@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
EH2_k127_914265_1	1485544.JQKP01000001_gene1259	2.411e-94	320.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
EH2_k127_914265_5	335283.Neut_2110	2.465e-26	108.0	COG1663@1|root,COG2835@1|root,COG1663@2|Bacteria,COG2835@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,372MY@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
EH2_k127_914265_8	314278.NB231_02018	4.917e-12	72.0	COG2882@1|root,COG2882@2|Bacteria,1PUHY@1224|Proteobacteria,1TAJQ@1236|Gammaproteobacteria,1X1NX@135613|Chromatiales	135613|Chromatiales	N	Flagellar FliJ protein	-	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
EH2_k127_914265_6	640081.Dsui_1751	2.274e-24	117.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,2VU2D@28216|Betaproteobacteria,2KX55@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar hook-length control protein FliK	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
EH2_k127_914265_7	1120999.JONM01000019_gene3417	2.347e-21	100.0	COG1580@1|root,COG1580@2|Bacteria,1RARK@1224|Proteobacteria,2VTGH@28216|Betaproteobacteria,2KRKK@206351|Neisseriales	206351|Neisseriales	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
EH2_k127_914265_0	1163617.SCD_n01234	5.981e-152	486.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
EH2_k127_916938_0	1123392.AQWL01000004_gene2758	8.615e-133	442.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,1KSY8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
EH2_k127_916938_1	1123393.KB891316_gene1390	1.59e-105	348.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KS6M@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Pyridoxal phosphate biosynthesis protein PdxJ	-	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
EH2_k127_916938_2	1097668.BYI23_A018920	4.232e-11	64.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,1K38E@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
EH2_k127_922087_6	292415.Tbd_0638	9.07e-26	112.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,1KRV3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	FixH	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
EH2_k127_922087_7	62928.azo1347	8.775e-05	46.0	2DTX1@1|root,33N25@2|Bacteria,1NNNE@1224|Proteobacteria,2VYM2@28216|Betaproteobacteria,2KXGV@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3149
EH2_k127_922087_0	1163617.SCD_n01230	9.282e-206	656.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
EH2_k127_922087_4	1121035.AUCH01000020_gene2653	7.463e-44	168.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,2KWS2@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
EH2_k127_922087_3	1163617.SCD_n01228	5.023e-139	451.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2VI19@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
EH2_k127_922087_1	1163617.SCD_n01227	1.579e-158	516.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
EH2_k127_922087_5	1163617.SCD_n01226	8.795e-27	112.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
EH2_k127_922087_2	1163617.SCD_n01225	3.867e-150	487.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
EH2_k127_927709_0	1304883.KI912532_gene2114	3.648e-83	282.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,2KU7N@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
EH2_k127_927709_2	1298593.TOL_1843	3.173e-62	220.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
EH2_k127_927709_1	1163617.SCD_n01166	1.658e-75	258.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
EH2_k127_933982_1	1123393.KB891316_gene1088	1.243e-113	368.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,1KRD7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
EH2_k127_933982_0	765911.Thivi_2177	1.423e-189	596.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1WX0M@135613|Chromatiales	135613|Chromatiales	GM	Male sterility protein	-	-	5.1.3.7	ko:K02473	ko00520,ko01100,map00520,map01100	-	R00418	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
EH2_k127_933982_2	1132855.KB913035_gene2403	0.0004414	48.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,2KKBD@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
EH2_k127_935_0	243233.MCA1761	1.049e-177	571.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XDXD@135618|Methylococcales	135618|Methylococcales	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
EH2_k127_935_1	485913.Krac_3083	9.613e-157	521.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
EH2_k127_961269_0	1232683.ADIMK_4139	0.0	1348.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,464EZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	IV02_11925	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
EH2_k127_961269_2	1485544.JQKP01000020_gene68	6.724e-105	346.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,44WAN@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
EH2_k127_961269_3	1123393.KB891316_gene1616	4.275e-56	197.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2VPAX@28216|Betaproteobacteria,1KT1P@119069|Hydrogenophilales	119069|Hydrogenophilales	H	6-pyruvoyl tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
EH2_k127_961269_1	640081.Dsui_3449	1.002e-110	380.0	COG2197@1|root,COG5001@1|root,COG2197@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9,Response_reg
EH2_k127_961269_4	522306.CAP2UW1_4238	3.69e-43	162.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	yfgF	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
EH2_k127_993858_2	1123367.C666_17260	3.108e-74	265.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,2KVC8@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_993858_0	76114.ebA3998	5.011e-159	508.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
EH2_k127_993858_4	1245471.PCA10_52240	1.224e-65	233.0	COG0515@1|root,COG0515@2|Bacteria,1RF4R@1224|Proteobacteria,1S7ZX@1236|Gammaproteobacteria,1YG4D@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH2_k127_993858_5	1198232.CYCME_0689	4.606e-58	219.0	COG0515@1|root,COG0515@2|Bacteria,1QU0D@1224|Proteobacteria,1T58D@1236|Gammaproteobacteria,462EW@72273|Thiotrichales	72273|Thiotrichales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
EH2_k127_993858_1	1026882.MAMP_02766	3.671e-89	299.0	COG0500@1|root,COG2226@2|Bacteria,1QXB0@1224|Proteobacteria,1T36U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
EH2_k127_993858_3	292415.Tbd_2522	2.039e-69	245.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
## 2301 queries scanned
## Total time (seconds): 55.93111205101013
## Rate: 41.14 q/s