## Tue Oct 15 19:52:22 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/GDHHQS1_bin.100.fa -m mmseqs --itype genome -o GDHHQS1_bin.100 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/GDHHQS1_bin.100 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS1_k127_10027572_0	886293.Sinac_2294	4.654e-299	929.0	COG1032@1|root,COG1032@2|Bacteria,2IY6B@203682|Planctomycetes	203682|Planctomycetes	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
GDHHQS1_k127_10027572_8	264462.Bd3206	8.955e-43	172.0	COG0400@1|root,COG0400@2|Bacteria,1N0UF@1224|Proteobacteria,42TUA@68525|delta/epsilon subdivisions,2MT5K@213481|Bdellovibrionales,2WQDY@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Serine hydrolase (FSH1)	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS1_k127_10027572_11	644966.Tmar_0336	2.85e-30	136.0	COG0500@1|root,COG1547@1|root,COG1547@2|Bacteria,COG2226@2|Bacteria,1V45D@1239|Firmicutes	1239|Firmicutes	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS1_k127_10027572_9	395019.Bmul_5824	1.525e-42	161.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,1K7IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	lipocalin	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
GDHHQS1_k127_10027572_6	264462.Bd3174	6.4e-54	214.0	COG0702@1|root,COG0702@2|Bacteria,1N8V3@1224|Proteobacteria,4307M@68525|delta/epsilon subdivisions,2WVDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10027572_5	439235.Dalk_2704	8.434e-60	216.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
GDHHQS1_k127_10027572_12	393921.HQ45_01475	1.648e-16	96.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,2FXZH@200643|Bacteroidia,22W8T@171551|Porphyromonadaceae	976|Bacteroidetes	S	Gliding motility protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
GDHHQS1_k127_10027572_1	378806.STAUR_3973	3.484e-200	642.0	COG3733@1|root,COG3733@2|Bacteria,1MW7W@1224|Proteobacteria	1224|Proteobacteria	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
GDHHQS1_k127_10027572_10	760568.Desku_1744	1.274e-39	164.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS1_k127_10027572_2	234267.Acid_0283	5.126e-99	350.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_10027572_4	309801.trd_A0816	1.325e-65	254.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS1_k127_10027572_7	1097668.BYI23_B011560	5.693e-47	191.0	COG0438@1|root,COG0438@2|Bacteria,1N0Z5@1224|Proteobacteria,2VRC8@28216|Betaproteobacteria,1K4W7@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_10027572_3	1303518.CCALI_00571	5.222e-87	293.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_10027572_13	936573.HMPREF1147_2160	2.537e-11	76.0	COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_1004727_0	671143.DAMO_1341	6.388e-56	202.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
GDHHQS1_k127_1004727_1	1142394.PSMK_22580	1.134e-13	79.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
GDHHQS1_k127_10135420_0	314345.SPV1_00095	1.069e-155	532.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS1_k127_10135420_1	696369.KI912183_gene2778	4.481e-16	78.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,2626V@186807|Peptococcaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GDHHQS1_k127_10140705_0	1396418.BATQ01000116_gene4615	2.079e-149	499.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS1_k127_10385_1	1232410.KI421418_gene2218	3.013e-07	60.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria,43U7P@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OprF membrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	HYR,Kelch_4,OMP_b-brl,OmpA,TSP_3
GDHHQS1_k127_10385_0	204669.Acid345_2557	2.324e-26	115.0	2B7KW@1|root,320RZ@2|Bacteria,3Y7ZF@57723|Acidobacteria,2JN97@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1057990_0	404589.Anae109_4264	0.0	1082.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
GDHHQS1_k127_1057990_4	1123519.PSJM300_10640	3.328e-59	222.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1YZQQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
GDHHQS1_k127_1057990_7	671143.DAMO_0961	7.16e-23	112.0	COG1538@1|root,COG1538@2|Bacteria,2NPI8@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_1057990_2	1173026.Glo7428_4416	3.069e-81	283.0	COG0753@1|root,COG0753@2|Bacteria,1G4T1@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalase	-	-	-	-	-	-	-	-	-	-	-	-	Catalase
GDHHQS1_k127_1057990_10	290397.Adeh_3797	2.613e-05	57.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3797|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1057990_8	305700.B447_18743	4.333e-18	96.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
GDHHQS1_k127_1057990_3	439235.Dalk_1753	9.078e-72	253.0	COG0300@1|root,COG0623@1|root,COG0300@2|Bacteria,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS1_k127_1057990_5	1192034.CAP_2447	2.81e-49	197.0	COG0332@1|root,COG0332@2|Bacteria,1RB9M@1224|Proteobacteria,42YNV@68525|delta/epsilon subdivisions,2WTQM@28221|Deltaproteobacteria,2YYYC@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS1_k127_1057990_6	610130.Closa_0034	1.712e-36	156.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,21YUI@1506553|Lachnoclostridium	186801|Clostridia	IQ	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS1_k127_1057990_9	439235.Dalk_1751	6.049e-15	87.0	COG0764@1|root,COG0764@2|Bacteria,1N0HJ@1224|Proteobacteria,42ZU6@68525|delta/epsilon subdivisions,2WV96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS1_k127_1057990_1	56780.SYN_01694	3.505e-120	407.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS1_k127_10582118_3	765869.BDW_14195	2.747e-35	143.0	2F91Y@1|root,341DM@2|Bacteria,1NXJ8@1224|Proteobacteria,430BR@68525|delta/epsilon subdivisions,2MTAE@213481|Bdellovibrionales,2WW54@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10582118_0	1237149.C900_05420	4.87e-235	737.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
GDHHQS1_k127_10582118_2	743722.Sph21_3921	1.047e-35	138.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS1_k127_10582118_1	886293.Sinac_4588	1.24e-104	346.0	COG0265@1|root,COG0265@2|Bacteria,2IYN3@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_1062511_2	1144275.COCOR_06150	1.122e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,42VYS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS1_k127_1062511_0	1379698.RBG1_1C00001G1773	2.599e-49	201.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
GDHHQS1_k127_1062511_1	243090.RB8754	4.793e-11	75.0	COG0457@1|root,COG0457@2|Bacteria,2IWZ3@203682|Planctomycetes	203682|Planctomycetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
GDHHQS1_k127_10728419_0	987059.RBXJA2T_07598	3.141e-117	380.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,1KJ5B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS1_k127_10728419_1	1112217.PPL19_17845	1.323e-60	211.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS1_k127_10795528_0	382464.ABSI01000010_gene3413	9.269e-107	356.0	COG3211@1|root,COG3211@2|Bacteria,46XDD@74201|Verrucomicrobia,2IVIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
GDHHQS1_k127_10795528_1	1279009.ADICEAN_03373	6.649e-88	306.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47JF7@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	yeeF	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
GDHHQS1_k127_10795528_2	313628.LNTAR_12216	1.801e-15	91.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_10858272_0	1121422.AUMW01000001_gene2410	1.907e-89	316.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1TRKP@1239|Firmicutes,248ZS@186801|Clostridia,261QZ@186807|Peptococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
GDHHQS1_k127_10858272_2	344747.PM8797T_03544	1.493e-46	175.0	COG0110@1|root,COG0110@2|Bacteria,2J0TB@203682|Planctomycetes	203682|Planctomycetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS1_k127_10858272_1	1244869.H261_13905	5.062e-79	284.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2TU42@28211|Alphaproteobacteria,2JT6F@204441|Rhodospirillales	204441|Rhodospirillales	M	UDP-N-acetylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2
GDHHQS1_k127_10858272_3	870187.Thini_1618	9.908e-40	152.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,45ZV0@72273|Thiotrichales	72273|Thiotrichales	M	NeuB family	-	-	2.5.1.101,2.5.1.56,2.5.1.97	ko:K01654,ko:K15898,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
GDHHQS1_k127_10914728_0	207559.Dde_2839	1.824e-151	498.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2M99R@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS1_k127_10914728_2	1111479.AXAR01000001_gene333	7.616e-56	207.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS1_k127_10914728_1	1303518.CCALI_02445	1.629e-78	278.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS1_k127_10914728_4	477641.MODMU_2349	0.0002839	44.0	COG0179@1|root,COG0179@2|Bacteria,2GMSJ@201174|Actinobacteria	201174|Actinobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS1_k127_10935432_0	1278073.MYSTI_05699	1.887e-108	372.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_10935432_1	767817.Desgi_1377	2.951e-93	327.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,2600X@186807|Peptococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS1_k127_10939374_1	649831.L083_3335	0.0008911	51.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
GDHHQS1_k127_10939374_0	404380.Gbem_2951	7.954e-35	155.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS1_k127_11017248_3	1151061.CAJY01000040_gene4041	8.611e-05	53.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
GDHHQS1_k127_11017248_2	243090.RB7376	2.418e-06	57.0	COG3266@1|root,COG3266@2|Bacteria,2J19D@203682|Planctomycetes	203682|Planctomycetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3299
GDHHQS1_k127_11017248_0	886293.Sinac_4851	2.077e-61	230.0	COG0577@1|root,COG0577@2|Bacteria,2IY8W@203682|Planctomycetes	203682|Planctomycetes	V	Permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_11017248_1	1040989.AWZU01000008_gene3750	6.19e-46	172.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,3K5Z0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
GDHHQS1_k127_1104111_2	720554.Clocl_2062	3.019e-05	56.0	COG1722@1|root,COG1722@2|Bacteria,1URN5@1239|Firmicutes,259IA@186801|Clostridia,3WMSC@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS1_k127_1104111_1	1499967.BAYZ01000158_gene455	3.435e-103	353.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS1_k127_1104111_0	404380.Gbem_0302	2.983e-187	616.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGIPQ	Acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
GDHHQS1_k127_11212160_12	641524.ADICYQ_4321	5.706e-09	59.0	COG3403@1|root,COG3403@2|Bacteria,4NH39@976|Bacteroidetes,47QY8@768503|Cytophagia	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	ko:K09190	-	-	-	-	ko00000	-	-	-	YqcI_YcgG
GDHHQS1_k127_11212160_9	1279009.ADICEAN_02069	4.33e-64	229.0	COG3665@1|root,COG3665@2|Bacteria,4NGIF@976|Bacteroidetes,47Q2I@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
GDHHQS1_k127_11212160_13	264462.Bd1528	1.669e-06	53.0	2EMKC@1|root,33F8T@2|Bacteria,1NP5C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11212160_11	234267.Acid_3437	3.47e-41	158.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS1_k127_11212160_7	395961.Cyan7425_1876	1.042e-73	262.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,3KGVF@43988|Cyanothece	1117|Cyanobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS1_k127_11212160_8	153721.MYP_3920	1.679e-66	241.0	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,47M87@768503|Cytophagia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
GDHHQS1_k127_11212160_1	477184.KYC_11573	1.903e-152	493.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,3T241@506|Alcaligenaceae	28216|Betaproteobacteria	C	NADH flavin oxidoreductases, Old Yellow Enzyme family	nemA	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
GDHHQS1_k127_11212160_6	404589.Anae109_0857	8.878e-78	290.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
GDHHQS1_k127_11212160_5	338966.Ppro_3008	1.022e-88	333.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
GDHHQS1_k127_11212160_4	1348657.M622_05555	2.231e-91	316.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2VH4R@28216|Betaproteobacteria,2KWA6@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GDHHQS1_k127_11212160_2	380703.AHA_3428	3.618e-125	424.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1Y442@135624|Aeromonadales	135624|Aeromonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS1_k127_11212160_3	1121405.dsmv_3561	1.237e-122	402.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,43BKT@68525|delta/epsilon subdivisions,2X6YX@28221|Deltaproteobacteria,2MJ3T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13892,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00348,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
GDHHQS1_k127_11212160_0	96561.Dole_0942	5.176e-206	658.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,42PKG@68525|delta/epsilon subdivisions,2WKPG@28221|Deltaproteobacteria,2MIZJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
GDHHQS1_k127_11212160_10	1121405.dsmv_3559	1.268e-42	157.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
GDHHQS1_k127_1124029_47	561175.KB894094_gene1749	7.175e-08	64.0	COG0392@1|root,COG0392@2|Bacteria,2I1QT@201174|Actinobacteria,4EPCF@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GDHHQS1_k127_1124029_49	1123261.AXDW01000009_gene40	7.465e-07	57.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1XC0E@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS1_k127_1124029_50	1184609.KILIM_003_00530	0.0003582	51.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4F74V@85018|Dermatophilaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS1_k127_1124029_11	264732.Moth_0985	2.288e-108	378.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia,42FX8@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	ndhF	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GDHHQS1_k127_1124029_10	1232410.KI421419_gene2539	1.67e-108	390.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42MBQ@68525|delta/epsilon subdivisions,2X5HD@28221|Deltaproteobacteria,43T5M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM-2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS1_k127_1124029_27	1071085.KK033114_gene833	1.101e-43	184.0	COG1007@1|root,arCOG01540@2157|Archaea,2XSY7@28890|Euryarchaeota,23SCD@183963|Halobacteria	183963|Halobacteria	C	COG1007 NADH ubiquinone oxidoreductase subunit 2 (chain N)	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS1_k127_1124029_44	221359.RS9916_38851	5.915e-12	79.0	COG0838@1|root,COG0838@2|Bacteria,1G5RH@1117|Cyanobacteria,1H0GX@1129|Synechococcus	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
GDHHQS1_k127_1124029_21	404589.Anae109_1291	3.645e-66	237.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WN9U@28221|Deltaproteobacteria,2YUX6@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3354	Oxidored_q6
GDHHQS1_k127_1124029_37	1131269.AQVV01000018_gene1932	1.856e-24	115.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
GDHHQS1_k127_1124029_3	1192034.CAP_0604	9.657e-129	424.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS1_k127_1124029_40	1051632.TPY_0861	6.951e-18	96.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,3WDH5@538999|Clostridiales incertae sedis	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS1_k127_1124029_7	394.NGR_c22070	3.74e-114	380.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2U2JT@28211|Alphaproteobacteria,4BB5D@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF2	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS1_k127_1124029_9	215803.DB30_0297	4.478e-113	384.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GDHHQS1_k127_1124029_15	1131269.AQVV01000018_gene1931	2.551e-83	306.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS1_k127_1124029_30	653733.Selin_0883	7.566e-33	145.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338,ko:K02573	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
GDHHQS1_k127_1124029_20	56780.SYN_02762	4.315e-68	242.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
GDHHQS1_k127_1124029_24	404589.Anae109_1099	1.211e-56	223.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
GDHHQS1_k127_1124029_38	56780.SYN_03140	1.197e-22	102.0	2C8BN@1|root,32RKS@2|Bacteria,1N7Z0@1224|Proteobacteria,42WEU@68525|delta/epsilon subdivisions,2WS8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1124029_43	1267533.KB906742_gene784	1.21e-12	81.0	COG2234@1|root,COG4932@1|root,COG5563@1|root,COG2234@2|Bacteria,COG4932@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	M	domain protein	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,PA,Peptidase_M28
GDHHQS1_k127_1124029_33	247490.KSU1_D0151	4.235e-31	138.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1124029_46	35754.JNYJ01000059_gene2237	5.976e-09	70.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,4DAY6@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_1124029_31	1173025.GEI7407_3459	3.354e-32	131.0	COG2032@1|root,COG2032@2|Bacteria,1G7HX@1117|Cyanobacteria,1HHGN@1150|Oscillatoriales	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
GDHHQS1_k127_1124029_23	525897.Dbac_1109	1.062e-58	209.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS1_k127_1124029_25	1120746.CCNL01000005_gene237	1.845e-53	204.0	COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS1_k127_1124029_26	335543.Sfum_1372	2.866e-44	171.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WM55@28221|Deltaproteobacteria,2MQDQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS1_k127_1124029_8	240016.ABIZ01000001_gene882	9.548e-114	377.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,2IU92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
GDHHQS1_k127_1124029_16	1144275.COCOR_03533	5.912e-83	307.0	COG0500@1|root,COG0500@2|Bacteria,1QX9N@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_1124029_28	243231.GSU2326	6.092e-37	156.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria,43VBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
GDHHQS1_k127_1124029_14	862908.BMS_1713	8.128e-91	307.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2MTIG@213481|Bdellovibrionales,2WMES@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS1_k127_1124029_6	1304885.AUEY01000019_gene1163	9.866e-124	409.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS1_k127_1124029_48	1381123.AYOD01000044_gene1792	2.099e-07	59.0	COG3793@1|root,COG3793@2|Bacteria,1RD1X@1224|Proteobacteria,2U788@28211|Alphaproteobacteria,43KFQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
GDHHQS1_k127_1124029_22	1144275.COCOR_02117	8.819e-64	225.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2Z38F@29|Myxococcales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS1_k127_1124029_17	1242864.D187_010288	1.996e-77	290.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
GDHHQS1_k127_1124029_2	1121033.AUCF01000001_gene1990	1.107e-148	485.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2JQ32@204441|Rhodospirillales	204441|Rhodospirillales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
GDHHQS1_k127_1124029_35	240015.ACP_1219	2.697e-26	119.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1124029_19	344747.PM8797T_03384	1.903e-68	244.0	COG3752@1|root,COG3752@2|Bacteria,2IZ0I@203682|Planctomycetes	203682|Planctomycetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
GDHHQS1_k127_1124029_5	1123377.AUIV01000021_gene2537	2.078e-126	427.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS1_k127_1124029_13	1458275.AZ34_07525	7.822e-95	323.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
GDHHQS1_k127_1124029_39	543913.D521_1831	7.941e-20	102.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,2VVUJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
GDHHQS1_k127_1124029_4	1121918.ARWE01000001_gene186	1.625e-127	426.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS1_k127_1124029_12	582744.Msip34_1299	1.393e-106	368.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,2KP5H@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS1_k127_1124029_32	1384056.N787_00680	1.215e-31	142.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	5.3.3.1	ko:K01822,ko:K21972	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SnoaL_2
GDHHQS1_k127_1124029_18	498761.HM1_1853	5.325e-75	271.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
GDHHQS1_k127_1124029_1	243233.MCA0095	2.875e-281	889.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XEV2@135618|Methylococcales	135618|Methylococcales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS1_k127_1124029_34	365046.Rta_09290	1.597e-28	129.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS1_k127_1124029_41	1382359.JIAL01000001_gene1287	1.312e-17	86.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GDHHQS1_k127_1124029_0	234267.Acid_4151	8.439e-315	1016.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS1_k127_1124029_42	290397.Adeh_3941	2.075e-14	86.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QGI@68525|delta/epsilon subdivisions,2X5YV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_1124029_29	639030.JHVA01000001_gene1094	1.506e-35	146.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1124029_45	69279.BG36_01755	5.184e-09	63.0	COG3293@1|root,COG3293@2|Bacteria,1RJFU@1224|Proteobacteria,2UB7T@28211|Alphaproteobacteria,43PPJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
GDHHQS1_k127_1124029_36	1120999.JONM01000015_gene2954	3.472e-26	118.0	COG2120@1|root,COG2120@2|Bacteria,1NUQU@1224|Proteobacteria,2W27T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS1_k127_1124962_14	1128421.JAGA01000002_gene308	1.564e-16	94.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_1124962_12	443143.GM18_2568	4.726e-25	121.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal
GDHHQS1_k127_1124962_11	555079.Toce_1601	5.836e-26	117.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,42FNR@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
GDHHQS1_k127_1124962_6	324602.Caur_2816	1.327e-54	216.0	COG0745@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,EAL,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_1124962_0	383372.Rcas_3083	2.721e-150	487.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi,3756K@32061|Chloroflexia	32061|Chloroflexia	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_1124962_2	240016.ABIZ01000001_gene2649	3.721e-144	469.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_1124962_3	518766.Rmar_1858	4.005e-140	454.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_1124962_10	1128421.JAGA01000002_gene742	2.584e-27	126.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS1_k127_1124962_1	383372.Rcas_4255	7.379e-149	484.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS1_k127_1124962_5	338963.Pcar_2954	8.817e-91	323.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
GDHHQS1_k127_1124962_7	765869.BDW_01575	5.156e-48	184.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2MTQZ@213481|Bdellovibrionales,2WNQ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	DJ	family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GDHHQS1_k127_1124962_13	1321778.HMPREF1982_01510	1.283e-23	115.0	COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,25EHZ@186801|Clostridia,26BZA@186813|unclassified Clostridiales	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_1124962_4	1278073.MYSTI_05612	5.149e-115	395.0	COG4122@1|root,COG4122@2|Bacteria,1QWCT@1224|Proteobacteria,43C6D@68525|delta/epsilon subdivisions,2X7GK@28221|Deltaproteobacteria,2Z3G7@29|Myxococcales	28221|Deltaproteobacteria	O	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1124962_9	1499967.BAYZ01000171_gene5548	2.215e-36	142.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS1_k127_11303459_0	497964.CfE428DRAFT_2683	1.344e-74	274.0	COG5426@1|root,COG5426@2|Bacteria,46U69@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11303459_1	1122962.AULH01000001_gene1521	0.0003572	53.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,36YJ1@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
GDHHQS1_k127_11306363_0	1132442.KB889752_gene3939	3.171e-224	709.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus	91061|Bacilli	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS1_k127_11306363_17	525309.HMPREF0494_0373	5.608e-27	128.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
GDHHQS1_k127_11306363_2	1121468.AUBR01000026_gene2924	2.638e-168	552.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,42ES5@68295|Thermoanaerobacterales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS1_k127_11306363_19	747365.Thena_1320	9.555e-15	78.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,42HIJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
GDHHQS1_k127_11306363_18	1121468.AUBR01000025_gene2970	2.33e-26	125.0	COG1287@1|root,COG1287@2|Bacteria,1V7EF@1239|Firmicutes,24M0T@186801|Clostridia,42HQV@68295|Thermoanaerobacterales	186801|Clostridia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11306363_4	635013.TherJR_1206	4.265e-139	483.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,260Q8@186807|Peptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS1_k127_11306363_5	401526.TcarDRAFT_0104	2.459e-107	383.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_11306363_10	56780.SYN_01565	5.611e-71	264.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MQCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS1_k127_11306363_8	269799.Gmet_2352	3.783e-78	280.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_11306363_11	1382359.JIAL01000001_gene993	5.843e-69	243.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
GDHHQS1_k127_11306363_9	1242864.D187_004762	4.757e-73	255.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GDHHQS1_k127_11306363_16	536232.CLM_4089	1.172e-40	157.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,36IPJ@31979|Clostridiaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS1_k127_11306363_12	1379698.RBG1_1C00001G1649	2.705e-66	239.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
GDHHQS1_k127_11306363_7	401526.TcarDRAFT_0093	1.961e-81	289.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,4H1ZV@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
GDHHQS1_k127_11306363_6	667014.Thein_0603	3.753e-85	312.0	COG4775@1|root,COG4775@2|Bacteria,2GGVC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS1_k127_11306363_1	1267535.KB906767_gene3340	1.158e-185	600.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GDHHQS1_k127_11306363_15	671143.DAMO_2608	1.004e-43	175.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_11306363_13	335543.Sfum_2924	9.883e-56	209.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43CWK@68525|delta/epsilon subdivisions,2WSJN@28221|Deltaproteobacteria,2MSI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_11306363_3	671143.DAMO_2610	1.043e-147	482.0	COG0160@1|root,COG0160@2|Bacteria,2NNRV@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36	ko:K03918,ko:K07250,ko:K20428	ko00250,ko00280,ko00410,ko00525,ko00640,ko00650,ko01100,ko01120,ko01130,map00250,map00280,map00410,map00525,map00640,map00650,map01100,map01120,map01130	M00027	R00457,R00908,R01648,R02773,R04188	RC00006,RC00062,RC00160,RC00781	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_11306363_14	671143.DAMO_2611	1.188e-46	180.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.29,6.3.2.30	ko:K03802,ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
GDHHQS1_k127_11315619_1	1499967.BAYZ01000147_gene695	2.222e-53	200.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
GDHHQS1_k127_11315619_0	1499967.BAYZ01000147_gene694	3.099e-99	352.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	-	-	1.3.3.15,1.3.3.4,5.4.99.9	ko:K00231,ko:K01854	ko00052,ko00520,ko00860,ko01100,ko01110,map00052,map00520,map00860,map01100,map01110	M00121	R00505,R03222,R04178,R09009	RC00317,RC00885,RC02396	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
GDHHQS1_k127_11315619_2	1218108.KB908291_gene700	6.467e-50	190.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS1_k127_11321141_18	85643.Tmz1t_1763	2.724e-08	61.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,2KVQ8@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_11321141_13	1123508.JH636445_gene6801	3.561e-38	148.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS1_k127_11321141_6	1184267.A11Q_1967	7.185e-106	354.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QQG@68525|delta/epsilon subdivisions,2MTKR@213481|Bdellovibrionales,2WMXN@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	Glucose / Sorbosone dehydrogenase	gdhB	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH,Ricin_B_lectin
GDHHQS1_k127_11321141_8	1380394.JADL01000003_gene4988	2.433e-93	340.0	COG0642@1|root,COG2199@1|root,COG0642@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TX5S@28211|Alphaproteobacteria,2JZ6H@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
GDHHQS1_k127_11321141_14	1297742.A176_05599	1.173e-37	163.0	COG0457@1|root,COG1629@1|root,COG0457@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2YU72@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
GDHHQS1_k127_11321141_19	269799.Gmet_2736	5.891e-05	57.0	COG2984@1|root,COG2984@2|Bacteria,1Q1HH@1224|Proteobacteria,42UE1@68525|delta/epsilon subdivisions,2WR33@28221|Deltaproteobacteria,43UYS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
GDHHQS1_k127_11321141_17	927677.ALVU02000001_gene2743	5.756e-28	117.0	COG2259@1|root,COG2259@2|Bacteria,1G88A@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX,SURF4
GDHHQS1_k127_11321141_9	1121866.AUGK01000017_gene1962	2.752e-90	320.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CUJ5@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS1_k127_11321141_11	1094508.Tsac_0615	2.799e-64	238.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
GDHHQS1_k127_11321141_2	279714.FuraDRAFT_2563	5.71e-143	483.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,2VPRG@28216|Betaproteobacteria,2KSUP@206351|Neisseriales	206351|Neisseriales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS1_k127_11321141_20	502025.Hoch_4573	0.0001103	55.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
GDHHQS1_k127_11321141_16	530564.Psta_3049	3.381e-34	136.0	2CGRW@1|root,33JMU@2|Bacteria,2J4DX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11321141_7	483219.LILAB_30825	7.097e-105	351.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2X5I0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS1_k127_11321141_1	1144275.COCOR_04760	9.346e-145	469.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2X5HZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS1_k127_11321141_3	794903.OPIT5_07085	7.632e-123	414.0	COG2317@1|root,COG2317@2|Bacteria,46TJB@74201|Verrucomicrobia,3K7EU@414999|Opitutae	414999|Opitutae	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GDHHQS1_k127_11321141_0	279714.FuraDRAFT_2562	1.398e-163	524.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,2KQFQ@206351|Neisseriales	206351|Neisseriales	E	Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GDHHQS1_k127_11321141_15	572547.Amico_1775	9.654e-36	145.0	COG1943@1|root,COG1943@2|Bacteria,3TC5I@508458|Synergistetes	508458|Synergistetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS1_k127_11321141_4	1123401.JHYQ01000014_gene822	7.763e-114	379.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,461ME@72273|Thiotrichales	72273|Thiotrichales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS1_k127_11321141_5	580332.Slit_0721	1.036e-107	369.0	COG0842@1|root,COG0842@2|Bacteria,1PX28@1224|Proteobacteria,2VYZC@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GDHHQS1_k127_11321141_10	671143.DAMO_2910	2.165e-77	275.0	2EHMT@1|root,33BDH@2|Bacteria	2|Bacteria	S	Alternative oxidase	-	-	-	-	-	-	-	-	-	-	-	-	AOX
GDHHQS1_k127_11321141_12	1267005.KB911257_gene1066	2.543e-47	181.0	29525@1|root,2ZSEY@2|Bacteria,1RF0P@1224|Proteobacteria,2U90Q@28211|Alphaproteobacteria,3N8GN@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11379208_0	450851.PHZ_c1055	1.646e-269	850.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2KFFV@204458|Caulobacterales	204458|Caulobacterales	P	Haloacid dehalogenase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GDHHQS1_k127_11379208_8	1242864.D187_000432	1.303e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_11379208_6	1121920.AUAU01000004_gene870	5.717e-61	221.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS1_k127_11379208_4	1267533.KB906733_gene3058	4.396e-99	333.0	COG2855@1|root,COG2855@2|Bacteria,3Y3R4@57723|Acidobacteria,2JHTG@204432|Acidobacteriia	204432|Acidobacteriia	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
GDHHQS1_k127_11379208_9	471870.BACINT_02328	4.056e-33	131.0	COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,2FT3R@200643|Bacteroidia,4ARM3@815|Bacteroidaceae	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS1_k127_11379208_12	456442.Mboo_0629	1.418e-06	56.0	arCOG09584@1|root,arCOG09584@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11379208_10	443255.SCLAV_5581	2.908e-13	85.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria	201174|Actinobacteria	L	Alpha beta hydrolase	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GDHHQS1_k127_11379208_5	44056.XP_009033895.1	1.722e-64	238.0	COG0275@1|root,KOG2782@2759|Eukaryota	2759|Eukaryota	M	rRNA (cytosine-N4-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS1_k127_11379208_7	472759.Nhal_0189	1.832e-54	214.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1X00D@135613|Chromatiales	135613|Chromatiales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS1_k127_11379208_14	1463857.JOFZ01000001_gene5387	0.0006659	52.0	COG1413@1|root,COG1413@2|Bacteria,2IIM7@201174|Actinobacteria	201174|Actinobacteria	C	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TIR_2
GDHHQS1_k127_11379208_1	525897.Dbac_1184	1.878e-162	529.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
GDHHQS1_k127_11379208_2	1123267.JONN01000001_gene638	1.211e-133	432.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2K1KY@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_11379208_11	404589.Anae109_0670	9.203e-07	57.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
GDHHQS1_k127_11379208_3	1192124.LIG30_0064	5.15e-120	399.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,1K6IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS1_k127_11513_6	335543.Sfum_2927	1.248e-35	151.0	COG1209@1|root,COG1209@2|Bacteria	335543.Sfum_2927|-	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11513_5	671143.DAMO_2613	1.799e-41	163.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.102,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20862	ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00548,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
GDHHQS1_k127_11513_1	404589.Anae109_0686	6.343e-53	201.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_11513_13	506534.Rhein_3642	5.565e-08	62.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
GDHHQS1_k127_11513_12	1167006.UWK_00797	3.557e-10	68.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GDHHQS1_k127_11513_2	1392540.P256_01434	3.294e-46	190.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,3NIVQ@468|Moraxellaceae	1236|Gammaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS1_k127_11513_15	1125863.JAFN01000001_gene1017	6.052e-06	60.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
GDHHQS1_k127_11513_11	926550.CLDAP_16330	1.961e-10	74.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS1_k127_11513_7	479434.Sthe_1787	1.266e-27	132.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS1_k127_11513_14	401053.AciPR4_1401	3.21e-06	61.0	COG0392@1|root,COG0392@2|Bacteria,3Y4Q3@57723|Acidobacteria,2JJ7R@204432|Acidobacteriia	204432|Acidobacteriia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS1_k127_11513_4	1123242.JH636434_gene4755	6.707e-42	175.0	COG0500@1|root,COG2226@2|Bacteria,2J52Z@203682|Planctomycetes	203682|Planctomycetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_11513_3	357808.RoseRS_2380	1.915e-45	183.0	COG0297@1|root,COG0297@2|Bacteria,2GBMD@200795|Chloroflexi,37794@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_11513_10	404380.Gbem_1791	9.004e-17	94.0	COG2244@1|root,COG2244@2|Bacteria,1RIXW@1224|Proteobacteria,42UIJ@68525|delta/epsilon subdivisions,2WQC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
GDHHQS1_k127_11513_0	479432.Sros_6500	1.251e-171	561.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4EI6C@85012|Streptosporangiales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS1_k127_11513_8	395494.Galf_0528	2.117e-22	113.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,2W3QT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11513_9	330214.NIDE3403	2.315e-17	85.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
GDHHQS1_k127_11557642_8	172045.KS04_03100	8.651e-36	144.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,1I8J7@117743|Flavobacteriia,34S6K@308865|Elizabethkingia	976|Bacteroidetes	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
GDHHQS1_k127_11557642_5	240015.ACP_2693	3.548e-95	342.0	COG1232@1|root,COG1232@2|Bacteria,3Y2X5@57723|Acidobacteria,2JI03@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS1_k127_11557642_2	448385.sce8628	7.425e-121	397.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
GDHHQS1_k127_11557642_16	1219035.NT2_04_03380	3.094e-08	66.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,2K6E5@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
GDHHQS1_k127_11557642_6	767817.Desgi_4028	7.606e-57	219.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS1_k127_11557642_0	1380391.JIAS01000017_gene544	8.321e-275	889.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,2JQXB@204441|Rhodospirillales	204441|Rhodospirillales	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
GDHHQS1_k127_11557642_13	414684.RC1_2227	1.181e-14	89.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2JQHE@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M48
GDHHQS1_k127_11557642_14	1267535.KB906767_gene3685	1.104e-11	79.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria,2JHIB@204432|Acidobacteriia	204432|Acidobacteriia	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS1_k127_11557642_11	880072.Desac_0901	2.64e-19	94.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
GDHHQS1_k127_11557642_1	497964.CfE428DRAFT_4581	1.066e-159	530.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
GDHHQS1_k127_11557642_10	290397.Adeh_3960	6.066e-22	102.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS1_k127_11557642_7	1007096.BAGW01000013_gene2474	1.173e-37	146.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,2N7BB@216572|Oscillospiraceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS1_k127_11557642_3	1173028.ANKO01000094_gene2620	2.166e-109	371.0	COG5316@1|root,COG5316@2|Bacteria,1GD0X@1117|Cyanobacteria,1HESQ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11557642_12	314262.MED193_12443	1.879e-17	85.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
GDHHQS1_k127_11557642_4	1244869.H261_21179	1.542e-95	327.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2JQNT@204441|Rhodospirillales	204441|Rhodospirillales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
GDHHQS1_k127_11557642_9	667014.Thein_0243	6.835e-29	122.0	COG0557@1|root,COG0557@2|Bacteria,2GH2N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS1_k127_1186657_17	886293.Sinac_3852	1.151e-66	238.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS1_k127_1186657_1	357808.RoseRS_3648	7.405e-186	594.0	COG0318@1|root,COG0318@2|Bacteria,2G5XY@200795|Chloroflexi,37755@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS1_k127_1186657_0	383372.Rcas_0489	1.049e-225	739.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,376WK@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS1_k127_1186657_5	357808.RoseRS_3650	4.208e-122	401.0	COG0171@1|root,COG0171@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GDHHQS1_k127_1186657_35	383372.Rcas_0491	7.587e-16	90.0	COG0236@1|root,COG0236@2|Bacteria,2G7GE@200795|Chloroflexi	200795|Chloroflexi	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS1_k127_1186657_14	762376.AXYL_06284	1.434e-68	247.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,3T1CS@506|Alcaligenaceae	1224|Proteobacteria	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
GDHHQS1_k127_1186657_31	1504672.669782768	2.478e-23	106.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
GDHHQS1_k127_1186657_23	395961.Cyan7425_3018	7.977e-47	186.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS1_k127_1186657_26	1173026.Glo7428_2699	5.638e-41	172.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_1186657_16	102129.Lepto7375DRAFT_1998	4.046e-68	253.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
GDHHQS1_k127_1186657_33	1121085.AUCI01000007_gene1178	2.302e-21	107.0	29FE7@1|root,302BX@2|Bacteria,1U6E5@1239|Firmicutes,4HEFF@91061|Bacilli,1ZPE9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1186657_27	84531.JMTZ01000166_gene1251	2.455e-39	166.0	COG0642@1|root,COG2205@2|Bacteria,1R8JB@1224|Proteobacteria,1TBWY@1236|Gammaproteobacteria,1X9E4@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS1_k127_1186657_2	743722.Sph21_2063	3.39e-182	590.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS1_k127_1186657_3	1210884.HG799469_gene14186	1.247e-155	504.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_1186657_24	1379270.AUXF01000004_gene3041	1.791e-46	193.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	fitD	-	-	ko:K19615	ko02020,map02020	-	-	-	ko00000,ko00001,ko02042	-	-	-	DUF1080,PPC,TcdA_TcdB_pore
GDHHQS1_k127_1186657_28	404380.Gbem_1080	1.189e-29	138.0	COG3979@1|root,COG4447@1|root,COG3979@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.132,3.2.1.14,3.2.1.17	ko:K01183,ko:K01233,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334,R02833	RC00467	ko00000,ko00001,ko01000	-	CBM15,GH18	-	CBM_5_12,Glyco_hydro_18,LPMO_10,fn3
GDHHQS1_k127_1186657_39	1519464.HY22_08670	9.335e-05	54.0	COG1555@1|root,COG1555@2|Bacteria,1FE73@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
GDHHQS1_k127_1186657_19	319795.Dgeo_1967	1.964e-55	213.0	COG1207@1|root,COG1207@2|Bacteria,1WIYX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS1_k127_1186657_40	289377.HL41_08560	0.0001803	47.0	COG4747@1|root,COG4747@2|Bacteria,2GHTH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GDHHQS1_k127_1186657_20	211165.AJLN01000094_gene1163	8.214e-55	202.0	COG0224@1|root,COG0224@2|Bacteria,1G9F2@1117|Cyanobacteria	1117|Cyanobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
GDHHQS1_k127_1186657_32	553207.HMPREF0299_7119	8.741e-22	106.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria,22NCW@1653|Corynebacteriaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS1_k127_1186657_13	859657.RPSI07_mp0835	2.342e-70	257.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VZW7@28216|Betaproteobacteria,1K2N1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS1_k127_1186657_30	1034943.BN1094_02621	5.575e-24	117.0	COG0457@1|root,COG0457@2|Bacteria,1NXTH@1224|Proteobacteria,1SQ9H@1236|Gammaproteobacteria,1JD0K@118969|Legionellales	118969|Legionellales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
GDHHQS1_k127_1186657_4	1121439.dsat_0477	1.9e-135	472.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,43D6S@68525|delta/epsilon subdivisions,2X8DM@28221|Deltaproteobacteria,2MACQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM General secretory system II protein E domain protein	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_trans_2_3,T2SSE_N
GDHHQS1_k127_1186657_7	1121335.Clst_2449	6.269e-112	373.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,3WH37@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	2.7.8.33,2.7.8.35,5.1.3.14	ko:K01791,ko:K02851	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R08856	RC00002,RC00290	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	Epimerase_2,Glycos_transf_4
GDHHQS1_k127_1186657_10	903818.KI912268_gene1215	1.605e-100	370.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	nodC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006807,GO:0007155,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022607,GO:0022610,GO:0030198,GO:0030203,GO:0030212,GO:0030213,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0042710,GO:0043062,GO:0043170,GO:0043436,GO:0044010,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0045226,GO:0046379,GO:0046394,GO:0050501,GO:0051704,GO:0071704,GO:0071840,GO:0071944,GO:0085029,GO:0090605,GO:0090609,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510	2.4.1.212	ko:K00752,ko:K14666	-	M00664	-	-	ko00000,ko00002,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Chitin_synth_2,Glyco_tranf_2_3,Glycos_transf_2,PilZ
GDHHQS1_k127_1186657_38	710421.Mycch_4589	1.84e-06	62.0	COG0726@1|root,COG0726@2|Bacteria,2GMZR@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_1186657_11	903818.KI912268_gene1213	3.45e-76	291.0	COG0457@1|root,COG0726@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	icaB	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K21478	-	-	R03096	RC00010	ko00000,ko01000	-	-	-	Polysacc_deac_1
GDHHQS1_k127_1186657_21	671143.DAMO_1129	2.526e-54	198.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1186657_29	929712.KI912613_gene550	9.709e-25	110.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1186657_25	483219.LILAB_04815	1.802e-44	179.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1R964@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,RsbRD_N
GDHHQS1_k127_1186657_22	858215.Thexy_2336	1.43e-52	195.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,42ESX@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	walR	-	-	ko:K07658,ko:K07667,ko:K07668,ko:K07776	ko02020,ko02024,map02020,map02024	M00434,M00443,M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1186657_9	1183438.GKIL_0318	1.114e-101	358.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_1186657_37	1123277.KB893195_gene5639	2.374e-07	58.0	2E32S@1|root,32Y2Z@2|Bacteria,4NW5U@976|Bacteroidetes,47RTP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1186657_34	1121422.AUMW01000045_gene1208	1.937e-17	92.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_1186657_12	330214.NIDE3821	1.047e-71	254.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS1_k127_1186657_8	880073.Calab_2583	2.045e-102	346.0	COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria	2|Bacteria	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS1_k127_1186657_15	1210884.HG799464_gene10872	2.794e-68	244.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
GDHHQS1_k127_1186657_36	1231391.AMZF01000017_gene180	2.304e-14	87.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2W8VK@28216|Betaproteobacteria,3T7DI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1186657_18	926567.TheveDRAFT_0540	2.657e-57	214.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_1186657_6	1210884.HG799465_gene12283	3.042e-119	389.0	COG0542@1|root,COG0542@2|Bacteria,2IWYZ@203682|Planctomycetes	203682|Planctomycetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS1_k127_11889187_0	931627.MycrhDRAFT_2939	8.514e-77	269.0	COG0477@1|root,COG2814@2|Bacteria,2HSJI@201174|Actinobacteria,23CNI@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_11889187_1	1144275.COCOR_00243	1.829e-38	158.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
GDHHQS1_k127_11889187_2	313606.M23134_06177	2.589e-21	99.0	COG4320@1|root,COG4320@2|Bacteria,4P18K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
GDHHQS1_k127_11903186_2	96561.Dole_2899	2.254e-59	220.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_11903186_1	435908.IDSA_00035	2.41e-126	416.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,2QFDG@267893|Idiomarinaceae	1236|Gammaproteobacteria	F	Adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS1_k127_11903186_3	290397.Adeh_2901	8.961e-42	171.0	COG0662@1|root,COG0662@2|Bacteria,1N1T5@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS1_k127_11903186_0	378806.STAUR_1076	2.467e-163	554.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YXS9@29|Myxococcales	28221|Deltaproteobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
GDHHQS1_k127_11903186_5	1463900.JOIX01000013_gene3440	1.924e-10	68.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS1_k127_11903186_4	448385.sce3890	2.443e-29	126.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,437WJ@68525|delta/epsilon subdivisions,2WYPZ@28221|Deltaproteobacteria,2YUGK@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	mmrA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS1_k127_11920181_6	604331.AUHY01000015_gene2630	1.679e-15	89.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS1_k127_11920181_5	264462.Bd0975	3.616e-71	253.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2MSW8@213481|Bdellovibrionales,2WUEA@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11920181_2	497964.CfE428DRAFT_1776	1.377e-137	445.0	COG4213@1|root,COG4213@2|Bacteria,46U6J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
GDHHQS1_k127_11920181_1	497964.CfE428DRAFT_1775	8.432e-194	626.0	COG1129@1|root,COG1129@2|Bacteria,46U21@74201|Verrucomicrobia	74201|Verrucomicrobia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GDHHQS1_k127_11920181_3	497964.CfE428DRAFT_1751	1.509e-129	443.0	COG4214@1|root,COG4214@2|Bacteria,46UBE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
GDHHQS1_k127_11920181_4	1267535.KB906767_gene340	9.786e-118	409.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria,2JI52@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
GDHHQS1_k127_11920181_0	469383.Cwoe_5411	1.553e-219	721.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS1_k127_11920482_1	1005048.CFU_1107	5.653e-104	346.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,47478@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
GDHHQS1_k127_11920482_0	1236959.BAMT01000001_gene1002	1.009e-185	586.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KKPJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS1_k127_11920482_2	365046.Rta_25080	5.089e-35	137.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4ABI0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS1_k127_12053704_4	153721.MYP_4377	1.532e-91	304.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,47PCP@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS1_k127_12053704_0	153721.MYP_2378	1.085e-191	616.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	sulP	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Sulfate_transp
GDHHQS1_k127_12053704_1	1341181.FLJC2902T_24920	4.699e-145	471.0	COG3746@1|root,COG3746@2|Bacteria,4NG5Z@976|Bacteroidetes,1I77C@117743|Flavobacteriia,2NSHC@237|Flavobacterium	976|Bacteroidetes	P	Pfam Phosphate-selective porin O and P	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
GDHHQS1_k127_12053704_2	926566.Terro_1031	8.143e-113	373.0	COG0226@1|root,COG0226@2|Bacteria,3Y399@57723|Acidobacteria,2JIVU@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS1_k127_12053704_6	204669.Acid345_2974	1.007e-77	274.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS1_k127_12053704_5	1267535.KB906767_gene584	3.53e-87	299.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria,2JHVP@204432|Acidobacteriia	204432|Acidobacteriia	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS1_k127_12053704_3	644966.Tmar_1646	6.33e-96	334.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WCRK@538999|Clostridiales incertae sedis	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS1_k127_12053704_7	765869.BDW_03490	5.26e-50	196.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42UYD@68525|delta/epsilon subdivisions,2MUPZ@213481|Bdellovibrionales,2WR5I@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS1_k127_12113889_22	1209989.TepiRe1_1339	4.635e-11	68.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,42HH3@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
GDHHQS1_k127_12113889_5	525897.Dbac_2738	9.722e-65	231.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
GDHHQS1_k127_12113889_18	1382359.JIAL01000001_gene1939	1.083e-25	116.0	COG1360@1|root,COG1360@2|Bacteria,3Y4KZ@57723|Acidobacteria,2JJ8N@204432|Acidobacteriia	204432|Acidobacteriia	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
GDHHQS1_k127_12113889_3	1121033.AUCF01000003_gene3067	4.092e-96	328.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JPHR@204441|Rhodospirillales	204441|Rhodospirillales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS1_k127_12113889_4	443144.GM21_2244	7.366e-84	305.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS1_k127_12113889_6	290397.Adeh_2532	1.026e-64	239.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
GDHHQS1_k127_12113889_2	945713.IALB_3149	2.373e-131	434.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
GDHHQS1_k127_12113889_1	1379698.RBG1_1C00001G1562	2.3e-147	497.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
GDHHQS1_k127_12113889_13	1449126.JQKL01000056_gene2268	1.584e-47	186.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,267X8@186813|unclassified Clostridiales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS1_k127_12113889_8	1254432.SCE1572_10325	1.555e-63	228.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2YUZ3@29|Myxococcales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS1_k127_12113889_0	644966.Tmar_0100	3.582e-187	632.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WCCX@538999|Clostridiales incertae sedis	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS1_k127_12113889_21	706587.Desti_1469	3.792e-16	91.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2MRZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS1_k127_12113889_19	1278073.MYSTI_03041	1.482e-25	120.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2YVM8@29|Myxococcales	28221|Deltaproteobacteria	O	peptidylprolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS1_k127_12113889_12	861299.J421_3744	1.741e-48	189.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GDHHQS1_k127_12113889_9	1121430.JMLG01000006_gene1724	1.024e-51	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_12113889_10	1449126.JQKL01000035_gene2174	8.872e-51	207.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_12113889_11	883109.HMPREF0380_01253	5.654e-50	204.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WCU7@538999|Clostridiales incertae sedis	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_12113889_23	43759.JNWK01000015_gene118	4.914e-08	65.0	COG3023@1|root,COG5640@1|root,COG3023@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,VCBS
GDHHQS1_k127_12113889_14	1121440.AUMA01000002_gene2080	1.373e-43	176.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2M82Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS1_k127_12113889_15	246197.MXAN_3705	5.129e-40	171.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria,2YTYN@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
GDHHQS1_k127_12113889_7	555079.Toce_2177	1.271e-64	234.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,24BP1@186801|Clostridia,42G2U@68295|Thermoanaerobacterales	186801|Clostridia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS1_k127_12113889_24	696369.KI912183_gene2134	1.187e-05	54.0	2E08C@1|root,32VW2@2|Bacteria,1VE5G@1239|Firmicutes,24P9V@186801|Clostridia,262E2@186807|Peptococcaceae	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS1_k127_12113889_17	1121472.AQWN01000002_gene2108	2.357e-30	131.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
GDHHQS1_k127_12113889_16	483219.LILAB_02730	2.753e-35	150.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2WINS@28221|Deltaproteobacteria,2YZ46@29|Myxococcales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS1_k127_12113889_20	1027273.GZ77_04955	2.375e-25	108.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XJH7@135619|Oceanospirillales	135619|Oceanospirillales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS1_k127_12119950_2	351160.RCIX1223	3.806e-100	332.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,2N97G@224756|Methanomicrobia	224756|Methanomicrobia	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
GDHHQS1_k127_12119950_1	1089553.Tph_c19890	1.516e-100	335.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS1_k127_12119950_10	1123518.ARWI01000001_gene230	2.7e-32	138.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,461SK@72273|Thiotrichales	72273|Thiotrichales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS1_k127_12119950_7	546274.EIKCOROL_00494	3.864e-59	213.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KPQ6@206351|Neisseriales	206351|Neisseriales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GDHHQS1_k127_12119950_3	644282.Deba_2111	1.877e-88	324.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS1_k127_12119950_0	1120746.CCNL01000017_gene3147	2.921e-134	446.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
GDHHQS1_k127_12119950_14	635013.TherJR_2129	2.767e-21	103.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_12119950_13	1125863.JAFN01000001_gene579	7.952e-22	100.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS1_k127_12119950_6	1396418.BATQ01000097_gene5956	2.396e-66	240.0	COG4409@1|root,COG4409@2|Bacteria,46V4S@74201|Verrucomicrobia,2IWB9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS1_k127_12119950_9	1121396.KB893077_gene747	6.148e-35	147.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
GDHHQS1_k127_12119950_20	309807.SRU_2196	1.143e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,1FJ20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
GDHHQS1_k127_12119950_8	330214.NIDE0206	8.042e-38	152.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12119950_11	82508.K1VVZ1	3.465e-31	127.0	COG0105@1|root,KOG0888@2759|Eukaryota,3A1MB@33154|Opisthokonta,3P274@4751|Fungi,3UYSH@5204|Basidiomycota,3VF1I@5234|Tremellales	4751|Fungi	F	NDK	ndk1	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006139,GO:0006165,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016049,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046939,GO:0050896,GO:0051211,GO:0051716,GO:0055086,GO:0061508,GO:0070013,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS1_k127_12119950_18	1244869.H261_09053	1.11e-11	76.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,2JSGU@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS1_k127_12119950_5	379066.GAU_0935	2.296e-66	237.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS1_k127_12119950_4	525904.Tter_0425	1.224e-81	295.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS1_k127_12119950_12	1267005.KB911256_gene1665	2.27e-30	132.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,2UGAS@28211|Alphaproteobacteria,3N8I1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS1_k127_12119950_17	796620.VIBC2010_05104	2.095e-12	76.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales	135623|Vibrionales	J	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GDHHQS1_k127_12119950_16	468556.AQYG01000043_gene236	1.507e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GBT5@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_12119950_15	880073.Calab_2217	9.568e-20	100.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
GDHHQS1_k127_12193485_4	1265505.ATUG01000001_gene3455	6.442e-45	177.0	COG2108@1|root,COG2108@2|Bacteria,1MY1Y@1224|Proteobacteria,42MIQ@68525|delta/epsilon subdivisions,2WJD2@28221|Deltaproteobacteria,2MHQT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_12193485_1	1121288.AULL01000011_gene1078	1.643e-181	579.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
GDHHQS1_k127_12193485_3	1192034.CAP_2191	1.364e-83	291.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_12193485_0	391625.PPSIR1_01954	1.895e-258	837.0	COG1145@1|root,COG2192@1|root,COG1145@2|Bacteria,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS1_k127_12193485_2	1192034.CAP_2187	2.62e-120	404.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_12358580_15	1123253.AUBD01000008_gene569	1.837e-27	125.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1X69P@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GDHHQS1_k127_12358580_12	1123072.AUDH01000002_gene2466	2.232e-38	161.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JRBS@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS1_k127_12358580_10	1379698.RBG1_1C00001G0613	7.435e-51	186.0	COG1268@1|root,COG1268@2|Bacteria,2NPGG@2323|unclassified Bacteria	2|Bacteria	S	BioY family	bioY	-	-	ko:K02014,ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	1.B.14,2.A.88.1,2.A.88.2	-	-	BioY
GDHHQS1_k127_12358580_1	398767.Glov_1587	1.892e-221	721.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
GDHHQS1_k127_12358580_11	469383.Cwoe_0014	8.595e-47	191.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS1_k127_12358580_13	296591.Bpro_4677	3.154e-33	138.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,4ADC0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GDHHQS1_k127_12358580_0	945713.IALB_1501	2.155e-235	744.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS1_k127_12358580_3	76114.ebA3150	3.547e-128	420.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2W1Q4@28216|Betaproteobacteria,2KXXH@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS1_k127_12358580_5	1242864.D187_007617	1.231e-111	373.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
GDHHQS1_k127_12358580_4	404589.Anae109_3723	1.884e-112	373.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2YTTU@29|Myxococcales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
GDHHQS1_k127_12358580_2	56107.Cylst_3344	6.041e-137	447.0	COG0722@1|root,COG0722@2|Bacteria,1G35W@1117|Cyanobacteria,1HIMM@1161|Nostocales	1117|Cyanobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS1_k127_12358580_19	1305836.AXVE01000006_gene448	2.386e-12	81.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,26GJU@186818|Planococcaceae	91061|Bacilli	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,PPC,Peptidase_S8,SLH
GDHHQS1_k127_12358580_7	1201288.M900_2073	3.353e-79	274.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
GDHHQS1_k127_12358580_8	1201288.M900_2071	5.688e-61	233.0	COG0287@1|root,COG0287@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
GDHHQS1_k127_12358580_6	1121405.dsmv_0798	1.445e-101	343.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2MJK2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_12358580_20	929506.CbC4_2358	2.164e-07	56.0	COG1605@1|root,COG1605@2|Bacteria,1UMCB@1239|Firmicutes,24VIX@186801|Clostridia	186801|Clostridia	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
GDHHQS1_k127_12358580_9	926554.KI912650_gene4179	4.863e-60	217.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GDHHQS1_k127_12358580_16	290397.Adeh_1449	8.851e-23	109.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS1_k127_12358580_14	1184267.A11Q_936	8.901e-32	135.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2MUGZ@213481|Bdellovibrionales,2WPAJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS1_k127_12358580_18	1379698.RBG1_1C00001G1334	2.071e-21	109.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
GDHHQS1_k127_12358580_17	747365.Thena_1685	1.511e-22	114.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,42EQ3@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM Flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
GDHHQS1_k127_12364030_7	243231.GSU0360	2.044e-32	130.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
GDHHQS1_k127_12364030_15	56110.Oscil6304_4074	3.953e-15	86.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
GDHHQS1_k127_12364030_10	234267.Acid_5912	2.589e-23	111.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS1_k127_12364030_5	1415779.JOMH01000001_gene2948	6.826e-38	160.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
GDHHQS1_k127_12364030_8	1286106.MPL1_08222	1.31e-26	122.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,45ZYG@72273|Thiotrichales	72273|Thiotrichales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS1_k127_12364030_9	880073.Calab_0980	3.525e-24	108.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_12364030_0	1430331.EP10_14735	2.246e-257	822.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1WEGA@129337|Geobacillus	91061|Bacilli	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
GDHHQS1_k127_12364030_11	349124.Hhal_1835	5.927e-23	116.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1WY9G@135613|Chromatiales	135613|Chromatiales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS1_k127_12364030_3	1123252.ATZF01000012_gene3741	7.627e-99	340.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,27BPG@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Uracil-5-)-methyltransferase	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS1_k127_12364030_14	443143.GM18_1117	2.176e-18	95.0	COG0457@1|root,COG0457@2|Bacteria	443143.GM18_1117|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12364030_2	697282.Mettu_0748	8.82e-166	557.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XDZ2@135618|Methylococcales	135618|Methylococcales	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS1_k127_12364030_4	234267.Acid_5619	2.646e-48	176.0	COG0780@1|root,COG0780@2|Bacteria,3Y4ND@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GDHHQS1_k127_12364030_12	573370.DMR_42900	2.795e-21	109.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2M8VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_12364030_13	1192034.CAP_2416	6.43e-19	101.0	COG3770@1|root,COG3770@2|Bacteria,1QA7G@1224|Proteobacteria,43DYC@68525|delta/epsilon subdivisions,2WZ6W@28221|Deltaproteobacteria,2Z1GB@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-insensitive murein endopeptidase	-	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
GDHHQS1_k127_12364030_6	1379270.AUXF01000002_gene1519	1.961e-33	134.0	COG2076@1|root,COG2076@2|Bacteria,1ZV9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
GDHHQS1_k127_12364030_1	240015.ACP_2162	6.643e-183	584.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria,2JHV7@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS1_k127_12509785_14	204669.Acid345_0108	5.554e-30	122.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS1_k127_12509785_7	204669.Acid345_0108	4.934e-63	235.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS1_k127_12509785_22	204669.Acid345_0109	6.172e-05	55.0	291F4@1|root,2ZP1Y@2|Bacteria,3Y93Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12509785_19	420662.Mpe_A0248	5.807e-10	66.0	2EGTE@1|root,33AJI@2|Bacteria,1N5DW@1224|Proteobacteria,2VUCZ@28216|Betaproteobacteria,1KMN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
GDHHQS1_k127_12509785_1	1379270.AUXF01000001_gene2345	4.307e-194	617.0	COG4262@1|root,COG4262@2|Bacteria,1ZU7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GDHHQS1_k127_12509785_2	497964.CfE428DRAFT_5205	8.458e-138	457.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.5.99.6	ko:K00316	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R01914,R01915	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS1_k127_12509785_11	1242864.D187_009899	1.992e-52	199.0	COG2114@1|root,COG2114@2|Bacteria,1Q6BC@1224|Proteobacteria,432SK@68525|delta/epsilon subdivisions,2WXUK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS1_k127_12509785_17	498848.TaqDRAFT_3064	3.548e-13	81.0	COG1714@1|root,COG1714@2|Bacteria,1WJWC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS1_k127_12509785_5	768706.Desor_5491	2.551e-80	281.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS1_k127_12509785_4	370438.PTH_2750	6.058e-100	332.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS1_k127_12509785_8	1501230.ET33_31810	5.351e-63	232.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,4HHE1@91061|Bacilli,26V5C@186822|Paenibacillaceae	91061|Bacilli	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS1_k127_12509785_6	1382315.JPOI01000001_gene1963	7.913e-74	258.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS1_k127_12509785_3	1121346.KB899830_gene681	7.731e-114	383.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,26QE9@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS1_k127_12509785_9	1291050.JAGE01000001_gene1929	1.44e-61	230.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
GDHHQS1_k127_12509785_16	517418.Ctha_0841	2.248e-17	91.0	COG0664@1|root,COG0664@2|Bacteria,1FFP9@1090|Chlorobi	1090|Chlorobi	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_12509785_23	756272.Plabr_3415	0.0001406	54.0	COG0457@1|root,COG0457@2|Bacteria	756272.Plabr_3415|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12509785_10	1210884.HG799464_gene10647	5.94e-55	206.0	COG1044@1|root,COG1044@2|Bacteria,2IY8X@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS1_k127_12509785_15	1038860.AXAP01000004_gene5135	7.379e-27	119.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2UBW9@28211|Alphaproteobacteria,3JYZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1304)	MA20_23345	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
GDHHQS1_k127_12509785_20	862908.BMS_0283	4.759e-08	63.0	COG3137@1|root,COG3137@2|Bacteria,1N2DE@1224|Proteobacteria,42W9S@68525|delta/epsilon subdivisions,2MT9W@213481|Bdellovibrionales,2WTC1@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
GDHHQS1_k127_12509785_18	1499689.CCNN01000013_gene3055	1.826e-11	73.0	COG1309@1|root,COG1309@2|Bacteria,1VFX3@1239|Firmicutes,24GN9@186801|Clostridia,36DJI@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
GDHHQS1_k127_12509785_12	264462.Bd0887	1.052e-33	149.0	COG1538@1|root,COG1538@2|Bacteria,1Q8XW@1224|Proteobacteria,43EZ7@68525|delta/epsilon subdivisions,2MT8A@213481|Bdellovibrionales,2X2QE@28221|Deltaproteobacteria	213481|Bdellovibrionales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS1_k127_12509785_0	264462.Bd1001	0.0	1046.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS1_k127_12509785_13	929712.KI912613_gene1508	7.234e-33	134.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_12509785_24	1297742.A176_03720	0.0001533	51.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
GDHHQS1_k127_12742406_3	518766.Rmar_2816	1.261e-22	104.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447,ko:K17733	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	-	-	Amidase_2,Big_2
GDHHQS1_k127_12742406_1	1089553.Tph_c09300	3.287e-58	216.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS1_k127_12742406_5	1476876.JOJO01000033_gene3952	5.189e-09	67.0	2E520@1|root,32ZV9@2|Bacteria,2ICNI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12742406_6	13349.G1X050	2.938e-08	68.0	29R2Z@1|root,2S1T4@2759|Eukaryota,39JIQ@33154|Opisthokonta,3Q3VX@4751|Fungi,3RKZ8@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12742406_2	469371.Tbis_1584	9.811e-55	201.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EA0B@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS1_k127_12742406_4	1297581.H919_05824	1.165e-19	104.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,21W5S@150247|Anoxybacillus	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS1_k127_12742406_7	1192034.CAP_5352	5.517e-05	54.0	COG0664@1|root,COG0664@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2YVYQ@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
GDHHQS1_k127_12742406_0	1304865.JAGF01000001_gene3209	4.92e-84	291.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_12840624_1	1123376.AUIU01000011_gene939	5.209e-174	563.0	COG0449@1|root,COG0449@2|Bacteria,3J0CP@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS1_k127_12840624_6	1042375.AFPL01000018_gene326	2.263e-58	224.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,464QE@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390	PdxJ
GDHHQS1_k127_12840624_2	1207063.P24_18456	1.285e-101	350.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JPJE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS1_k127_12840624_5	1125863.JAFN01000001_gene2162	3.887e-67	238.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
GDHHQS1_k127_12840624_0	1123376.AUIU01000012_gene1515	3.016e-196	628.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	40117|Nitrospirae	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS1_k127_12840624_7	485916.Dtox_0723	2.12e-56	202.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS1_k127_12840624_8	163908.KB235896_gene3557	2.013e-55	215.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HKT0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_12840624_9	358823.DF19_00570	5.32e-22	101.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_12840624_4	383372.Rcas_1090	5.846e-80	284.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,3750N@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS1_k127_12840624_3	880073.Calab_1153	2.076e-85	302.0	COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_12840624_11	1123253.AUBD01000002_gene1420	3.069e-06	60.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SZJ7@1236|Gammaproteobacteria,1X76A@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS1_k127_12840624_10	266117.Rxyl_1156	7.672e-07	62.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_8
GDHHQS1_k127_12870117_0	886293.Sinac_5028	9.251e-116	395.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWWI@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
GDHHQS1_k127_12943273_0	264201.pc1296	3.002e-39	161.0	COG1994@1|root,COG1994@2|Bacteria,2JFYC@204428|Chlamydiae	204428|Chlamydiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
GDHHQS1_k127_1301415_2	128390.XP_009471004.1	3.425e-05	56.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa,3CV1I@33213|Bilateria,485N6@7711|Chordata,4962A@7742|Vertebrata,4GM0F@8782|Aves	33208|Metazoa	S	Transmembrane protein 260	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS1_k127_1301415_0	1379698.RBG1_1C00001G1690	6.146e-12	78.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
GDHHQS1_k127_1301415_1	1125700.HMPREF9195_00885	1.196e-08	69.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
GDHHQS1_k127_13077439_4	1396418.BATQ01000049_gene364	1.2e-20	96.0	COG1186@1|root,COG1186@2|Bacteria,46T84@74201|Verrucomicrobia,2IUUG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
GDHHQS1_k127_13077439_2	1121920.AUAU01000005_gene1089	1.146e-63	227.0	COG0218@1|root,COG0218@2|Bacteria,3Y4H6@57723|Acidobacteria	57723|Acidobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
GDHHQS1_k127_13077439_0	414684.RC1_3493	1.484e-220	704.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2JYHC@204441|Rhodospirillales	204441|Rhodospirillales	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS1_k127_13077439_1	335543.Sfum_2433	4.721e-145	477.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
GDHHQS1_k127_13077439_3	335543.Sfum_1748	3.042e-40	160.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2X227@28221|Deltaproteobacteria,2MQQ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS1_k127_13082142_6	1123368.AUIS01000007_gene2732	1.11e-50	203.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,1S0NW@1236|Gammaproteobacteria,2NBVS@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
GDHHQS1_k127_13082142_3	316067.Geob_2770	9.274e-74	274.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_13082142_7	1449065.JMLL01000010_gene1210	2.567e-41	164.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,43HWJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GDHHQS1_k127_13082142_9	1288484.APCS01000087_gene1571	4.522e-24	111.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GDHHQS1_k127_13082142_1	580327.Tthe_2222	4.895e-99	331.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42FEE@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GDHHQS1_k127_13082142_8	591019.Shell_0553	2.588e-39	166.0	COG1073@1|root,arCOG01651@2157|Archaea,2XQ83@28889|Crenarchaeota	28889|Crenarchaeota	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	DUF829,Hydrolase_4,Peptidase_S15
GDHHQS1_k127_13082142_4	264732.Moth_0141	5.337e-73	268.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS1_k127_13082142_12	251229.Chro_0595	0.0002312	54.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,3VIZR@52604|Pleurocapsales	1117|Cyanobacteria	M	PDZ domain (Also known as DHR or GLGF)	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
GDHHQS1_k127_13082142_2	1121920.AUAU01000013_gene1697	7.306e-77	280.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
GDHHQS1_k127_13082142_0	525904.Tter_0805	1.071e-159	514.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS1_k127_13082142_11	290397.Adeh_3736	6.629e-09	69.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS1_k127_13082142_10	228410.NE2076	3.056e-09	71.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,373ZZ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GDHHQS1_k127_13082142_5	1303518.CCALI_01551	4.405e-63	242.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	kinB	-	2.7.13.3	ko:K11383	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,KinB_sensor,PAS,PAS_4
GDHHQS1_k127_13136734_2	224325.AF_1672	5.211e-15	80.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GDHHQS1_k127_13136734_1	1229203.KI301992_gene738	7.956e-17	91.0	COG0121@1|root,COG0121@2|Bacteria,2GJSY@201174|Actinobacteria	201174|Actinobacteria	S	glutamine amidotransferase	-	-	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_4
GDHHQS1_k127_13136734_4	269797.Mbar_A1826	3.871e-07	61.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
GDHHQS1_k127_13136734_5	521011.Mpal_2732	0.0001367	53.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
GDHHQS1_k127_13136734_0	445970.ALIPUT_00499	3.529e-81	288.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22U05@171550|Rikenellaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS1_k127_13138129_5	502025.Hoch_3311	3.809e-05	59.0	COG0793@1|root,COG0793@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
GDHHQS1_k127_13138129_3	1379698.RBG1_1C00001G1818	1.343e-08	67.0	COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13138129_4	1123508.JH636439_gene568	4.99e-06	60.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GDHHQS1_k127_13138129_1	443143.GM18_0093	1.27e-43	166.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
GDHHQS1_k127_13138129_0	264462.Bd0975	1.679e-69	243.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2MSW8@213481|Bdellovibrionales,2WUEA@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13138129_2	1122971.BAME01000021_gene2294	4.399e-15	76.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,22WGY@171551|Porphyromonadaceae	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS1_k127_13141518_22	1298863.AUEP01000003_gene2728	0.0003641	54.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GDHHQS1_k127_13141518_23	1172180.KB911779_gene5624	0.0003983	51.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
GDHHQS1_k127_13141518_1	1150599.MPHLEI_10860	2.284e-130	428.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,232EC@1762|Mycobacteriaceae	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS1_k127_13141518_8	635013.TherJR_1549	5.771e-69	246.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS1_k127_13141518_0	247490.KSU1_C0978	6.547e-203	659.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
GDHHQS1_k127_13141518_9	477974.Daud_0599	2.898e-61	231.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS1_k127_13141518_21	696747.NIES39_Q00360	0.0002042	51.0	COG1426@1|root,COG1426@2|Bacteria,1GQRC@1117|Cyanobacteria,1HI75@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
GDHHQS1_k127_13141518_19	1500894.JQNN01000001_gene475	4.166e-07	57.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,4730Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
GDHHQS1_k127_13141518_3	869210.Marky_2167	3.88e-124	432.0	COG0606@1|root,COG0606@2|Bacteria,1WI18@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS1_k127_13141518_11	1232410.KI421421_gene3883	2.423e-51	207.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria,43UI6@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS1_k127_13141518_15	411467.BACCAP_00408	3.867e-23	116.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,267W5@186813|unclassified Clostridiales	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS1_k127_13141518_4	404589.Anae109_3433	4.803e-104	349.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_13141518_13	484770.UFO1_1113	5.766e-31	124.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4H57U@909932|Negativicutes	909932|Negativicutes	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GDHHQS1_k127_13141518_7	1214166.ALLG01000021_gene36	2.27e-79	276.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1WT0K@1307|Streptococcus suis	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
GDHHQS1_k127_13141518_17	215803.DB30_2248	3.122e-15	78.0	COG4576@1|root,COG4576@2|Bacteria,1Q8QH@1224|Proteobacteria,4354D@68525|delta/epsilon subdivisions,2WZFG@28221|Deltaproteobacteria,2Z20V@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
GDHHQS1_k127_13141518_18	1123075.AUDP01000004_gene820	5.059e-13	80.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3WMQW@541000|Ruminococcaceae	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS1_k127_13141518_6	96561.Dole_2898	2.618e-81	296.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13141518_10	1242864.D187_003088	3.985e-61	235.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
GDHHQS1_k127_13141518_5	96561.Dole_2898	5.688e-85	303.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13141518_12	536233.CLO_3296	2.986e-36	143.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,36I0M@31979|Clostridiaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS1_k127_13141518_14	411467.BACCAP_01552	1.632e-30	127.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,267XA@186813|unclassified Clostridiales	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GDHHQS1_k127_13141518_2	406124.ACPC01000022_gene4197	2.902e-129	429.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli,1ZSC0@1386|Bacillus	91061|Bacilli	C	Aldehyde dehydrogenase family	acdH	-	1.1.1.1,1.2.1.10,1.2.1.87	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS1_k127_13141518_16	1184609.KILIM_086_00040	2.306e-20	93.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria	201174|Actinobacteria	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS1_k127_13143166_1	1313265.JNIE01000004_gene528	5.984e-111	370.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS1_k127_13143166_2	234267.Acid_1085	4.99e-69	257.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS1_k127_13143166_3	338963.Pcar_1236	1.132e-48	200.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GDHHQS1_k127_13143166_0	671143.DAMO_0682	3.073e-271	856.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS1_k127_13158737_20	2055.JNXA01000003_gene4431	4.152e-31	131.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4GAWR@85026|Gordoniaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknD	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS1_k127_13158737_27	998088.B565_3379	7.576e-13	81.0	2DM20@1|root,31DN4@2|Bacteria,1R86I@1224|Proteobacteria,1S9Q6@1236|Gammaproteobacteria,1Y5Y7@135624|Aeromonadales	135624|Aeromonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13158737_28	1144275.COCOR_06514	2.364e-11	71.0	29VAW@1|root,30GR0@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
GDHHQS1_k127_13158737_7	1198114.AciX9_0264	5.697e-110	370.0	COG0493@1|root,COG0493@2|Bacteria,3Y3EA@57723|Acidobacteria,2JJCC@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R10159,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS1_k127_13158737_2	1120973.AQXL01000108_gene1962	1.087e-168	545.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,278QV@186823|Alicyclobacillaceae	91061|Bacilli	CF	4Fe-4S dicluster domain	preA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
GDHHQS1_k127_13158737_23	1007104.SUS17_3487	1.089e-21	101.0	COG0457@1|root,COG0457@2|Bacteria,1NKPJ@1224|Proteobacteria,2UM7X@28211|Alphaproteobacteria,2K5JZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13158737_6	1396141.BATP01000059_gene2564	5.563e-133	432.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS1_k127_13158737_0	448385.sce4721	4.854e-213	687.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales	28221|Deltaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GDHHQS1_k127_13158737_3	234267.Acid_7659	2.722e-167	540.0	COG0044@1|root,COG0044@2|Bacteria,3Y48H@57723|Acidobacteria	57723|Acidobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GDHHQS1_k127_13158737_14	96561.Dole_2900	9.212e-74	278.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13158737_12	96561.Dole_2900	9.191e-78	275.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13158737_25	404589.Anae109_1632	1.346e-15	87.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GDHHQS1_k127_13158737_5	204669.Acid345_1459	1.533e-140	465.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria,2JIX2@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_13158737_8	1396141.BATP01000059_gene2568	1.018e-107	372.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS1_k127_13158737_4	1111479.AXAR01000001_gene175	2.352e-151	495.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,27912@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
GDHHQS1_k127_13158737_9	537007.BLAHAN_05589	1.235e-96	328.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS1_k127_13158737_15	1304880.JAGB01000003_gene995	4.063e-72	257.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
GDHHQS1_k127_13158737_13	1499967.BAYZ01000026_gene1561	2.293e-74	273.0	COG1176@1|root,COG1176@2|Bacteria,2NPH4@2323|unclassified Bacteria	2|Bacteria	E	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10675	BPD_transp_1
GDHHQS1_k127_13158737_16	1118054.CAGW01000005_gene3793	1.903e-57	221.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,274ZZ@186822|Paenibacillaceae	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS1_k127_13158737_18	1379698.RBG1_1C00001G1645	5.749e-38	150.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
GDHHQS1_k127_13158737_11	96561.Dole_2898	2.251e-79	283.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13158737_21	1396141.BATP01000007_gene5576	2.96e-22	109.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS1_k127_13158737_17	690850.Desaf_3749	1.002e-52	199.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2M8GB@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
GDHHQS1_k127_13158737_26	1379698.RBG1_1C00001G1155	3.052e-15	79.0	COG0858@1|root,COG0858@2|Bacteria,2NPXH@2323|unclassified Bacteria	2|Bacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS1_k127_13158737_1	1125863.JAFN01000001_gene1429	3.664e-191	626.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GDHHQS1_k127_13158737_10	1379698.RBG1_1C00001G1152	4.522e-91	316.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
GDHHQS1_k127_13158737_19	264732.Moth_1046	3.201e-33	133.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,42GU2@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
GDHHQS1_k127_13158737_22	710687.KI912270_gene5650	1.079e-21	108.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria,2379C@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13158737_24	1144312.PMI09_00574	6.588e-21	103.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2U6VS@28211|Alphaproteobacteria,4BM30@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS1_k127_13163689_10	290315.Clim_0026	6.703e-15	78.0	COG2127@1|root,COG2127@2|Bacteria,1FEA2@1090|Chlorobi	1090|Chlorobi	S	PFAM ATP-dependent Clp protease adaptor protein ClpS	-	-	-	-	-	-	-	-	-	-	-	-	ClpS
GDHHQS1_k127_13163689_1	671143.DAMO_2934	4.672e-104	348.0	COG0667@1|root,COG0667@2|Bacteria,2NS4R@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	ydjG	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_13163689_7	1173028.ANKO01000154_gene4735	5.647e-24	119.0	COG0457@1|root,COG0457@2|Bacteria	1173028.ANKO01000154_gene4735|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13163689_9	10181.XP_004875162.1	1.561e-19	105.0	COG0457@1|root,KOG1124@2759|Eukaryota,38DM6@33154|Opisthokonta,3BEU3@33208|Metazoa,3CW6P@33213|Bilateria,485D1@7711|Chordata,48XAY@7742|Vertebrata,3J72H@40674|Mammalia,35IEN@314146|Euarchontoglires,4PZZ4@9989|Rodentia	33208|Metazoa	O	tetratricopeptide repeat	TTC6	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_13163689_4	1123389.ATXJ01000018_gene970	4.419e-78	271.0	COG0685@1|root,COG0685@2|Bacteria,1WI80@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GDHHQS1_k127_13163689_6	283699.D172_1442	5.065e-53	213.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
GDHHQS1_k127_13163689_5	880073.Calab_1131	7.795e-63	226.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_1131|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13163689_2	880073.Calab_1130	3.027e-86	297.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
GDHHQS1_k127_13163689_11	880073.Calab_0199	7.044e-12	76.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
GDHHQS1_k127_13163689_0	1049564.TevJSym_aa02510	2.069e-131	439.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1J544@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
GDHHQS1_k127_13163689_3	1121374.KB891585_gene1951	8.383e-85	308.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS1_k127_13163689_8	518766.Rmar_2601	1.352e-21	109.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,1FJ20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
GDHHQS1_k127_13163689_12	290397.Adeh_3855	5.484e-07	62.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2WW4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS1_k127_13252376_1	1184267.A11Q_1982	5.661e-69	242.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2MT3N@213481|Bdellovibrionales,2WPJY@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GDHHQS1_k127_13252376_0	1122182.KB903822_gene1203	1.441e-89	334.0	COG2373@1|root,COG2373@2|Bacteria,2H4M3@201174|Actinobacteria,4DCH5@85008|Micromonosporales	201174|Actinobacteria	G	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
GDHHQS1_k127_13292227_3	1009370.ALO_01205	4.017e-87	310.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4H2TU@909932|Negativicutes	1239|Firmicutes	M	Monogalactosyldiacylglycerol synthase, C-terminal domain protein	ypfP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
GDHHQS1_k127_13292227_2	1244869.H261_01836	9.839e-113	369.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2JQH4@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
GDHHQS1_k127_13292227_1	1121920.AUAU01000018_gene1825	8.741e-183	586.0	COG0514@1|root,COG0514@2|Bacteria,3Y2KM@57723|Acidobacteria	57723|Acidobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RecQ_Zn_bind
GDHHQS1_k127_13292227_5	1192034.CAP_2492	1.343e-43	168.0	COG1024@1|root,COG1024@2|Bacteria,1MWGT@1224|Proteobacteria,4314E@68525|delta/epsilon subdivisions,2WWTK@28221|Deltaproteobacteria,2Z3AC@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GDHHQS1_k127_13292227_6	1379698.RBG1_1C00001G1032	4.199e-29	129.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS1_k127_13292227_8	643562.Daes_2099	1.541e-23	112.0	COG0859@1|root,COG0859@2|Bacteria,1N112@1224|Proteobacteria,42MUI@68525|delta/epsilon subdivisions,2WRZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GDHHQS1_k127_13292227_0	264462.Bd0709	1.594e-190	625.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2MTI3@213481|Bdellovibrionales,2X727@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
GDHHQS1_k127_13292227_4	765869.BDW_10970	8.741e-62	227.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2MTTT@213481|Bdellovibrionales,2WM23@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	macrolide-specific efflux protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS1_k127_13292227_7	340177.Cag_0335	1.307e-26	121.0	COG1538@1|root,COG1538@2|Bacteria,1FDME@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_13304642_0	1379698.RBG1_1C00001G1854	1.277e-160	516.0	COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS1_k127_13304642_2	1382303.JPOM01000001_gene1767	4.896e-85	287.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2KF55@204458|Caulobacterales	204458|Caulobacterales	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_13304642_3	1382359.JIAL01000001_gene3029	2.153e-82	279.0	COG2057@1|root,COG2057@2|Bacteria,3Y3EC@57723|Acidobacteria,2JIV4@204432|Acidobacteriia	204432|Acidobacteriia	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_13304642_5	349161.Dred_2286	1.431e-31	130.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_13304642_1	1313421.JHBV01000041_gene3629	2.659e-120	415.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
GDHHQS1_k127_13304642_4	903818.KI912268_gene2018	7.555e-57	203.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS1_k127_13308807_6	42256.RradSPS_2004	3.6e-79	296.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4CQGG@84995|Rubrobacteria	84995|Rubrobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS1_k127_13308807_17	941449.dsx2_1651	5.84e-08	66.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2M8CA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS1_k127_13308807_7	382464.ABSI01000011_gene2704	6.576e-79	285.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,2ITV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS1_k127_13308807_12	1121346.KB899809_gene3646	1.619e-43	168.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	yqiK	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS1_k127_13308807_10	429009.Adeg_1471	2.151e-51	192.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,42GGH@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GDHHQS1_k127_13308807_15	1329516.JPST01000005_gene1362	5.336e-23	100.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,27C7R@186824|Thermoactinomycetaceae	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
GDHHQS1_k127_13308807_14	479434.Sthe_0397	1.083e-25	113.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi,27YCQ@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS1_k127_13308807_16	756272.Plabr_3341	3.525e-19	98.0	COG2146@1|root,COG2151@1|root,COG2146@2|Bacteria,COG2151@2|Bacteria,2J020@203682|Planctomycetes	203682|Planctomycetes	P	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,Rieske
GDHHQS1_k127_13308807_13	1183438.GKIL_1934	1.808e-26	125.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS1_k127_13308807_3	266117.Rxyl_0166	3.218e-138	451.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS1_k127_13308807_9	215803.DB30_6994	1.223e-60	232.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2YY27@29|Myxococcales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS1_k127_13308807_4	697282.Mettu_2997	5.345e-115	374.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1XE5C@135618|Methylococcales	135618|Methylococcales	O	ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS1_k127_13308807_0	1382359.JIAL01000001_gene678	2.711e-253	786.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS1_k127_13308807_8	292459.STH1268	2.091e-78	276.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS1_k127_13308807_1	502025.Hoch_6480	5.662e-216	704.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_13308807_11	4792.ETI57659	1.351e-47	183.0	COG1028@1|root,KOG1201@2759|Eukaryota,3QDAA@4776|Peronosporales	4776|Peronosporales	Q	KR domain	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
GDHHQS1_k127_13308807_2	671143.DAMO_0332	1.425e-144	469.0	COG0014@1|root,COG0014@2|Bacteria,2NQM3@2323|unclassified Bacteria	2|Bacteria	E	Aldehyde dehydrogenase family	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0293,iYO844.BSU13130	Aldedh
GDHHQS1_k127_13308807_5	671143.DAMO_0331	1.522e-101	341.0	COG0263@1|root,COG0263@2|Bacteria,2NQMJ@2323|unclassified Bacteria	2|Bacteria	E	PUA domain	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
GDHHQS1_k127_13310130_1	1415780.JPOG01000001_gene884	5.554e-47	175.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
GDHHQS1_k127_13310130_0	1242864.D187_009296	6.556e-127	435.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2YU2M@29|Myxococcales	28221|Deltaproteobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
GDHHQS1_k127_13310130_2	1269813.ATUL01000026_gene2596	7.582e-43	171.0	COG3608@1|root,COG3608@2|Bacteria,1MV55@1224|Proteobacteria,1S6VH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
GDHHQS1_k127_13310130_3	498761.HM1_1704	1.31e-22	102.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
GDHHQS1_k127_13310130_4	518766.Rmar_0598	2.179e-20	91.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1FIV2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS1_k127_13399958_6	648996.Theam_0610	7.045e-52	201.0	COG0503@1|root,COG0503@2|Bacteria,2G4K7@200783|Aquificae	200783|Aquificae	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GDHHQS1_k127_13399958_5	1121004.ATVC01000004_gene1476	5.72e-56	209.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KQAU@206351|Neisseriales	206351|Neisseriales	K	RNA polymerase sigma factor	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_13399958_10	1150399.AQYK01000002_gene2690	6.566e-20	92.0	COG1254@1|root,COG1254@2|Bacteria,2HZJD@201174|Actinobacteria,4FQ1C@85023|Microbacteriaceae	201174|Actinobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS1_k127_13399958_11	667632.KB890172_gene3973	1.749e-17	86.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,1K7KJ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS1_k127_13399958_12	1267535.KB906767_gene253	3.534e-13	79.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS1_k127_13399958_9	643562.Daes_1416	2.514e-30	127.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2M8KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS1_k127_13399958_4	476272.RUMHYD_00309	4.355e-62	226.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3XYNR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS1_k127_13399958_7	118005.AWNK01000002_gene1764	4.726e-37	147.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS1_k127_13399958_1	477974.Daud_1110	5.507e-87	320.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS1_k127_13399958_2	1116472.MGMO_41c00110	1.829e-70	259.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13399958_3	644282.Deba_0825	1.057e-65	235.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS1_k127_13399958_13	112098.XP_008620665.1	3.581e-13	74.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	ANKRD65	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4
GDHHQS1_k127_13399958_0	1121440.AUMA01000003_gene2989	1.223e-89	313.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2M8C7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS1_k127_13399958_14	1051501.AYTL01000027_gene566	1.99e-09	63.0	COG4405@1|root,COG4405@2|Bacteria,1VDG5@1239|Firmicutes,4HM8P@91061|Bacilli,1ZKFH@1386|Bacillus	91061|Bacilli	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
GDHHQS1_k127_13399958_8	1254432.SCE1572_00030	2.935e-35	140.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2X5PR@28221|Deltaproteobacteria,2Z36S@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS1_k127_13450762_1	661478.OP10G_3269	1.187e-76	266.0	COG2089@1|root,COG2089@2|Bacteria	2|Bacteria	M	N-acylneuraminate-9-phosphate synthase activity	neuB	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
GDHHQS1_k127_13450762_0	1382304.JNIL01000001_gene1736	2.397e-84	288.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,278S1@186823|Alicyclobacillaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_13577743_10	1896.JOAU01000024_gene3582	0.0003064	55.0	COG4733@1|root,COG4733@2|Bacteria,2GNV7@201174|Actinobacteria	201174|Actinobacteria	E	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
GDHHQS1_k127_13577743_8	945713.IALB_2930	6.812e-05	56.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13577743_9	41431.PCC8801_1300	0.000272	54.0	COG0457@1|root,COG0457@2|Bacteria,1GIT8@1117|Cyanobacteria,3KHZU@43988|Cyanothece	1117|Cyanobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8,Trypsin_2
GDHHQS1_k127_13577743_5	935948.KE386495_gene1935	3.859e-41	170.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,42EU1@68295|Thermoanaerobacterales	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS1_k127_13577743_6	266265.Bxe_B0221	1.606e-26	113.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KG4B@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_13577743_4	401526.TcarDRAFT_0046	5.211e-50	204.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4H20Z@909932|Negativicutes	909932|Negativicutes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS1_k127_13577743_2	1047013.AQSP01000137_gene516	4.862e-138	464.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS1_k127_13577743_7	644282.Deba_3300	1.747e-16	85.0	COG3807@1|root,COG3807@2|Bacteria,1N5AB@1224|Proteobacteria,42URU@68525|delta/epsilon subdivisions,2WQYJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS1_k127_13577743_3	335543.Sfum_2381	5.888e-66	239.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS1_k127_13577743_0	642492.Clole_2579	1.978e-171	550.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS1_k127_13577743_1	1304880.JAGB01000002_gene1835	2.596e-165	533.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS1_k127_13607726_7	768710.DesyoDRAFT_4178	1.341e-15	86.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS14760	CO_deh_flav_C,FAD_binding_5
GDHHQS1_k127_13607726_5	1192034.CAP_0075	3.15e-42	179.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z13I@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS1_k127_13607726_0	861299.J421_2138	5.32e-225	718.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS1_k127_13607726_4	298386.PBPRB0863	1.067e-45	176.0	COG2010@1|root,COG2010@2|Bacteria,1RCYF@1224|Proteobacteria,1SEBP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS1_k127_13607726_6	1231392.OCGS_0264	8.552e-20	105.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS1_k127_13607726_2	670307.HYPDE_33213	9.757e-128	429.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
GDHHQS1_k127_13607726_1	269799.Gmet_2573	2.47e-160	521.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS1_k127_13607726_3	1288494.EBAPG3_12710	2.525e-93	317.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS1_k127_13817570_0	1269813.ATUL01000002_gene953	2.503e-120	396.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucoamylase and related glycosyl hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS1_k127_13817570_1	411477.PARMER_00734	1.364e-12	68.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,2FPNC@200643|Bacteroidia,22WRB@171551|Porphyromonadaceae	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
GDHHQS1_k127_13939141_12	246197.MXAN_5906	6.292e-57	209.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,437WJ@68525|delta/epsilon subdivisions,2WYPZ@28221|Deltaproteobacteria,2YUGK@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	mmrA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS1_k127_13939141_26	713587.THITH_04115	1.047e-26	115.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
GDHHQS1_k127_13939141_8	497964.CfE428DRAFT_5338	1.856e-82	287.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
GDHHQS1_k127_13939141_17	290397.Adeh_4291	7.952e-45	173.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS1_k127_13939141_29	1565314.OA34_01615	1.088e-21	99.0	COG2849@1|root,COG2849@2|Bacteria,1MZCG@1224|Proteobacteria,42XCP@68525|delta/epsilon subdivisions,2YQ7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
GDHHQS1_k127_13939141_30	1121035.AUCH01000007_gene498	2.367e-21	103.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,2KV54@206389|Rhodocyclales	206389|Rhodocyclales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
GDHHQS1_k127_13939141_10	290397.Adeh_2142	1.342e-59	210.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
GDHHQS1_k127_13939141_23	95619.PM1_0219330	9.773e-31	141.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ykoW	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
GDHHQS1_k127_13939141_1	1120999.JONM01000007_gene1751	5.167e-138	473.0	COG0642@1|root,COG2199@1|root,COG4251@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS1_k127_13939141_3	266117.Rxyl_3138	7.779e-128	417.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS1_k127_13939141_7	886293.Sinac_3668	4.309e-92	319.0	COG0534@1|root,COG0534@2|Bacteria,2IX5Q@203682|Planctomycetes	203682|Planctomycetes	V	COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GDHHQS1_k127_13939141_0	926549.KI421517_gene999	2.996e-300	940.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GDHHQS1_k127_13939141_2	671143.DAMO_2815	4.18e-130	436.0	COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	MA20_28645	-	3.6.3.29,3.6.3.41	ko:K06022,ko:K06158,ko:K10834	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS1_k127_13939141_20	1125863.JAFN01000001_gene3571	1.012e-36	149.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,43AXT@68525|delta/epsilon subdivisions,2X6BZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_13939141_6	1165841.SULAR_09719	6.44e-107	367.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_13939141_9	886293.Sinac_1076	3.763e-68	236.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS1_k127_13939141_11	96561.Dole_2898	3.549e-57	226.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_13939141_5	452637.Oter_0943	9.475e-111	370.0	COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia,3K7N6@414999|Opitutae	414999|Opitutae	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS1_k127_13939141_25	483219.LILAB_16085	5.914e-28	128.0	COG2356@1|root,COG4935@1|root,COG2356@2|Bacteria,COG4935@2|Bacteria,1MXQM@1224|Proteobacteria,42P2N@68525|delta/epsilon subdivisions,2WT6E@28221|Deltaproteobacteria,2YV8G@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,P_proprotein
GDHHQS1_k127_13939141_14	1278073.MYSTI_07712	1.123e-54	200.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
GDHHQS1_k127_13939141_24	944480.ATUV01000002_gene36	5.028e-29	126.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WQCU@28221|Deltaproteobacteria,2M78V@213113|Desulfurellales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS1_k127_13939141_28	1125863.JAFN01000001_gene972	4.62e-26	126.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
GDHHQS1_k127_13939141_16	1348114.OM33_01040	2.114e-45	183.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
GDHHQS1_k127_13939141_22	118005.AWNK01000007_gene739	8.515e-33	144.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria	2|Bacteria	M	chlorophyll binding	oprF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03286,ko:K07275	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,OprF
GDHHQS1_k127_13939141_31	313598.MED152_00005	4.588e-06	59.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1HZFD@117743|Flavobacteriia,3VV79@52959|Polaribacter	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
GDHHQS1_k127_13939141_32	517418.Ctha_0342	9.699e-05	54.0	COG0737@1|root,COG3391@1|root,COG0737@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
GDHHQS1_k127_13939141_27	1128421.JAGA01000003_gene3270	2.12e-26	113.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS1_k127_13939141_15	207954.MED92_15023	9.758e-47	177.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1XJ8V@135619|Oceanospirillales	135619|Oceanospirillales	K	response regulator	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS1_k127_13939141_18	290397.Adeh_1997	1.924e-43	173.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,42PU2@68525|delta/epsilon subdivisions,2X60T@28221|Deltaproteobacteria,2Z327@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_13939141_19	1121035.AUCH01000001_gene1740	2.843e-38	165.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2VKWI@28216|Betaproteobacteria,2KV4U@206389|Rhodocyclales	206389|Rhodocyclales	T	Cache 3/Cache 2 fusion domain	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
GDHHQS1_k127_13939141_13	1163617.SCD_n00935	9.892e-57	224.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria	1224|Proteobacteria	NT	Chemotaxis	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HWE_HK,PAS,PAS_10,PAS_4
GDHHQS1_k127_13939141_4	1121918.ARWE01000001_gene2188	1.261e-111	384.0	2DBEC@1|root,2Z8RY@2|Bacteria,1MXRI@1224|Proteobacteria,42ZNW@68525|delta/epsilon subdivisions,2WUUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
GDHHQS1_k127_13939141_21	448385.sce0315	1.47e-33	141.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2,YjbH
GDHHQS1_k127_14037326_1	340.xcc-b100_4009	1.127e-12	81.0	COG0526@1|root,COG0526@2|Bacteria,1MWU8@1224|Proteobacteria,1SFUW@1236|Gammaproteobacteria,1X970@135614|Xanthomonadales	135614|Xanthomonadales	M	Protein of unknown function, DUF255	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_7
GDHHQS1_k127_14037326_0	1040986.ATYO01000009_gene2255	3.716e-116	427.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,43J1Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS1_k127_14042766_6	713586.KB900536_gene637	1.972e-102	359.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales	135613|Chromatiales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
GDHHQS1_k127_14042766_24	502025.Hoch_5233	5.815e-28	116.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,4315K@68525|delta/epsilon subdivisions,2WWYY@28221|Deltaproteobacteria,2YVYB@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GDHHQS1_k127_14042766_14	330214.NIDE3921	5.73e-48	183.0	29TFP@1|root,30ENV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GDHHQS1_k127_14042766_9	211165.AJLN01000116_gene3219	1.942e-65	240.0	COG2204@1|root,COG4251@1|root,COG2204@2|Bacteria,COG4251@2|Bacteria,1G3QY@1117|Cyanobacteria	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS1_k127_14042766_38	944480.ATUV01000001_gene988	0.0001444	53.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,437DK@68525|delta/epsilon subdivisions,2WSN1@28221|Deltaproteobacteria,2M76S@213113|Desulfurellales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS1_k127_14042766_33	637389.Acaty_c2651	5.577e-09	63.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,2ND1Z@225057|Acidithiobacillales	225057|Acidithiobacillales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS1_k127_14042766_22	682795.AciX8_4402	2.542e-29	126.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
GDHHQS1_k127_14042766_7	1254432.SCE1572_30505	1.983e-90	308.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2Z39N@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS1_k127_14042766_30	1173263.Syn7502_02393	4.8e-19	101.0	2EGMM@1|root,33ADT@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
GDHHQS1_k127_14042766_11	857087.Metme_3247	6.727e-61	220.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
GDHHQS1_k127_14042766_3	1303518.CCALI_00138	2.056e-117	386.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS1_k127_14042766_17	575540.Isop_3543	9.765e-43	167.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS1_k127_14042766_19	502025.Hoch_4089	9.083e-37	162.0	COG1657@1|root,COG1657@2|Bacteria,1QX5U@1224|Proteobacteria,42ZX1@68525|delta/epsilon subdivisions,2WVF4@28221|Deltaproteobacteria,2YV56@29|Myxococcales	28221|Deltaproteobacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS1_k127_14042766_10	502025.Hoch_4088	5.828e-65	256.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
GDHHQS1_k127_14042766_31	42256.RradSPS_1227	5.332e-13	83.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GDHHQS1_k127_14042766_36	983917.RGE_34680	1.811e-07	64.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1KMJ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_14042766_27	181119.XP_005528667.1	1.21e-22	116.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa,3CV1I@33213|Bilateria,485N6@7711|Chordata,4962A@7742|Vertebrata,4GM0F@8782|Aves	33208|Metazoa	S	Transmembrane protein 260	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS1_k127_14042766_20	1379270.AUXF01000001_gene2642	1.625e-36	145.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS1_k127_14042766_29	1411685.U062_01149	1.924e-21	106.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1J67X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
GDHHQS1_k127_14042766_26	386415.NT01CX_2124	4.757e-24	115.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,36FYW@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_14042766_37	111781.Lepto7376_0832	0.000117	55.0	COG1426@1|root,COG1426@2|Bacteria,1G5I6@1117|Cyanobacteria,1HBBI@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG1426 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
GDHHQS1_k127_14042766_32	221027.JO40_07250	2.253e-09	70.0	COG1426@1|root,COG1426@2|Bacteria,2J61E@203691|Spirochaetes	203691|Spirochaetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
GDHHQS1_k127_14042766_34	519989.ECTPHS_10129	1.28e-08	65.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1WXHE@135613|Chromatiales	135613|Chromatiales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GDHHQS1_k127_14042766_2	1274374.CBLK010000032_gene3133	4.552e-122	420.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,26QH8@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS1_k127_14042766_23	762966.HMPREF9439_00660	3.002e-29	123.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,4PR70@995019|Sutterellaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS1_k127_14042766_0	379066.GAU_1764	4.769e-205	661.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS1_k127_14042766_25	661087.HMPREF1008_01482	8.631e-27	111.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CW78@84998|Coriobacteriia	84998|Coriobacteriia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS1_k127_14042766_18	1254432.SCE1572_26500	1.251e-42	169.0	COG0642@1|root,COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
GDHHQS1_k127_14042766_8	1121468.AUBR01000009_gene2161	3.254e-67	256.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS1_k127_14042766_28	1278073.MYSTI_07373	4.531e-22	98.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria,42XQS@68525|delta/epsilon subdivisions,2WTAP@28221|Deltaproteobacteria,2YVXV@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
GDHHQS1_k127_14042766_1	404589.Anae109_2974	4.051e-132	429.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WME2@28221|Deltaproteobacteria,2YWHE@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_14042766_12	568816.Acin_1506	2.114e-55	200.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4H3ZW@909932|Negativicutes	909932|Negativicutes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS1_k127_14042766_15	468059.AUHA01000008_gene2730	2.51e-46	173.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS1_k127_14042766_16	187272.Mlg_2847	1.86e-44	176.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS1_k127_14042766_13	404589.Anae109_1500	4.427e-49	186.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS1_k127_14042766_21	1089550.ATTH01000001_gene2483	5.346e-31	138.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1FK2K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
GDHHQS1_k127_14042766_5	644966.Tmar_0917	5.813e-114	391.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WCFK@538999|Clostridiales incertae sedis	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS1_k127_14042766_4	547144.HydHO_0626	7.029e-115	385.0	COG0162@1|root,COG0162@2|Bacteria,2G3IP@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS1_k127_14042766_35	880073.Calab_1787	1.228e-07	62.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,OmpA,TPR_16,fn3
GDHHQS1_k127_14079383_0	1121930.AQXG01000006_gene782	2.605e-89	309.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPQC@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
GDHHQS1_k127_14100847_0	1165096.ARWF01000001_gene501	6.722e-187	593.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,2KKQ3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
GDHHQS1_k127_14100847_1	1121405.dsmv_3194	9.41e-45	169.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS1_k127_14107468_0	203119.Cthe_0686	1.042e-104	351.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS1_k127_14107468_1	316067.Geob_3015	4.123e-45	174.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS1_k127_14242337_12	1500301.JQMF01000019_gene5000	1.093e-21	98.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,4BEKI@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
GDHHQS1_k127_14242337_10	319795.Dgeo_0422	5.019e-42	176.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39_2
GDHHQS1_k127_14242337_11	909663.KI867150_gene688	3.616e-33	148.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	ydhO	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SLH
GDHHQS1_k127_14242337_1	1121920.AUAU01000023_gene2396	1.222e-143	468.0	COG0773@1|root,COG1376@1|root,COG0773@2|Bacteria,COG1376@2|Bacteria,3Y304@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the MurCDEF family	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M,YkuD
GDHHQS1_k127_14242337_4	1121377.KB906402_gene3238	1.869e-67	252.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
GDHHQS1_k127_14242337_13	1499967.BAYZ01000173_gene5810	3.752e-19	102.0	COG0745@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	2.7.13.3	ko:K02003,ko:K02484	-	M00258	-	-	ko00000,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_14242337_9	945713.IALB_2285	1.152e-42	174.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS1_k127_14242337_6	484019.THA_297	1.723e-58	211.0	COG0432@1|root,COG0432@2|Bacteria,2GD4B@200918|Thermotogae	200918|Thermotogae	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS1_k127_14242337_5	1266914.ATUK01000013_gene1808	7.226e-59	214.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS1_k127_14242337_3	469371.Tbis_0205	9.305e-68	239.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DXYV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GDHHQS1_k127_14242337_2	374847.Kcr_1093	2.449e-141	468.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS1_k127_14242337_8	1123288.SOV_3c01930	1.274e-43	178.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4H27I@909932|Negativicutes	909932|Negativicutes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GDHHQS1_k127_14242337_7	313628.LNTAR_12581	4.194e-48	181.0	2CAZH@1|root,2Z7RU@2|Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS1_k127_14242337_0	234267.Acid_7402	1.483e-310	973.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS1_k127_14281161_1	1167006.UWK_01936	2.778e-125	416.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS1_k127_14281161_3	1379698.RBG1_1C00001G1850	2.113e-54	203.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS1_k127_14281161_8	1260356.D920_02021	6.849e-31	138.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,4B2ES@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
GDHHQS1_k127_14281161_0	671143.DAMO_2251	4.583e-180	574.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS1_k127_14281161_7	759914.BP951000_1905	3.469e-34	152.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J6RF@203691|Spirochaetes	203691|Spirochaetes	M	LysM domain M23 M37 peptidase domain protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS1_k127_14281161_6	326427.Cagg_2410	7.16e-40	167.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi,377CS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS1_k127_14281161_10	1121946.AUAX01000014_gene1212	1.591e-07	64.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D9MF@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS1_k127_14281161_4	483219.LILAB_26945	3.505e-47	195.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
GDHHQS1_k127_14281161_5	1379698.RBG1_1C00001G0657	4.497e-45	166.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GDHHQS1_k127_14281161_9	1384054.N790_04185	1.101e-26	116.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X7FM@135614|Xanthomonadales	135614|Xanthomonadales	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS1_k127_14281161_2	546271.Selsp_2191	1.243e-97	329.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H286@909932|Negativicutes	909932|Negativicutes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS1_k127_14410597_19	944480.ATUV01000001_gene1378	8.246e-84	285.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
GDHHQS1_k127_14410597_27	319795.Dgeo_0757	1.386e-64	237.0	COG1459@1|root,COG1459@2|Bacteria,1WIU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	PFAM Bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS1_k127_14410597_66	1177181.T9A_02640	0.0004097	53.0	COG4968@1|root,COG4968@2|Bacteria,1QXFJ@1224|Proteobacteria	1224|Proteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
GDHHQS1_k127_14410597_40	335543.Sfum_3126	1.005e-35	150.0	COG3394@1|root,COG3394@2|Bacteria,1PP3A@1224|Proteobacteria,42R6K@68525|delta/epsilon subdivisions,2WN1Q@28221|Deltaproteobacteria,2MRXE@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	YdjC-like protein	hpnK	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GDHHQS1_k127_14410597_53	93220.LV28_21780	1.152e-17	96.0	COG0392@1|root,COG0392@2|Bacteria,1MWRY@1224|Proteobacteria,2W1IU@28216|Betaproteobacteria,1JZTT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GDHHQS1_k127_14410597_25	269799.Gmet_2815	7.923e-70	256.0	COG1215@1|root,COG1215@2|Bacteria,1PC79@1224|Proteobacteria,42QYP@68525|delta/epsilon subdivisions,2X6HG@28221|Deltaproteobacteria,43UDX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	hpnI	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
GDHHQS1_k127_14410597_4	1380394.JADL01000005_gene5573	9.048e-206	650.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TRFJ@28211|Alphaproteobacteria,2JRB5@204441|Rhodospirillales	204441|Rhodospirillales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS1_k127_14410597_64	309801.trd_1637	1.538e-05	59.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS1_k127_14410597_49	251221.35214818	1.752e-22	113.0	COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_14410597_0	523791.Kkor_2113	0.0	1043.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XHCH@135619|Oceanospirillales	135619|Oceanospirillales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS1_k127_14410597_41	404589.Anae109_3198	2.246e-34	147.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GDHHQS1_k127_14410597_5	1242864.D187_009374	1.353e-200	637.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS1_k127_14410597_34	1242864.D187_008066	4.63e-48	177.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS1_k127_14410597_57	861299.J421_0071	2.589e-09	69.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	2.7.13.3	ko:K03407,ko:K12257	ko02020,ko02024,ko02030,ko03060,ko03070,map02020,map02024,map02030,map03060,map03070	M00335,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	2.A.6.4	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS1_k127_14410597_48	358823.DF19_00570	1.906e-24	117.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_14410597_31	391625.PPSIR1_13375	3.517e-55	215.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS1_k127_14410597_12	1242864.D187_001751	3.047e-125	429.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2YUH6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
GDHHQS1_k127_14410597_10	379066.GAU_0616	6.095e-129	438.0	COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GDHHQS1_k127_14410597_46	518766.Rmar_0682	4.007e-26	121.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_0682|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14410597_22	984262.SGRA_1938	5.619e-76	274.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS1_k127_14410597_65	313612.L8106_18976	3.237e-05	53.0	COG3117@1|root,COG3117@2|Bacteria,1G0PJ@1117|Cyanobacteria,1H74D@1150|Oscillatoriales	1117|Cyanobacteria	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
GDHHQS1_k127_14410597_17	1321779.HMPREF1984_00354	4.499e-93	316.0	COG2877@1|root,COG2877@2|Bacteria,3786I@32066|Fusobacteria	32066|Fusobacteria	H	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS1_k127_14410597_2	1125863.JAFN01000001_gene910	3.619e-215	685.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
GDHHQS1_k127_14410597_28	1279038.KB907342_gene2676	1.475e-61	222.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,2JPST@204441|Rhodospirillales	204441|Rhodospirillales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS1_k127_14410597_20	671143.DAMO_0267	4.775e-82	299.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
GDHHQS1_k127_14410597_50	439235.Dalk_0281	6.807e-22	112.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WNBB@28221|Deltaproteobacteria,2MK5J@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
GDHHQS1_k127_14410597_29	401526.TcarDRAFT_0106	9.327e-61	234.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,4H97G@909932|Negativicutes	909932|Negativicutes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_N,LpxK
GDHHQS1_k127_14410597_37	903818.KI912269_gene362	1.35e-41	173.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaQ	-	-	ko:K02841,ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS1_k127_14410597_36	760568.Desku_3298	2.99e-43	174.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_14410597_33	644282.Deba_0712	3.625e-48	182.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_14410597_42	648996.Theam_0005	2.715e-29	132.0	COG0438@1|root,COG0438@2|Bacteria,2G49S@200783|Aquificae	200783|Aquificae	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.87	ko:K00743	ko00601,map00601	-	R05978,R06169	-	ko00000,ko00001,ko01000,ko01003	-	GT6	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_14410597_43	1121406.JAEX01000018_gene2815	4.397e-29	136.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WPW4@28221|Deltaproteobacteria,2MCTH@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_14410597_24	1125863.JAFN01000001_gene534	4.185e-71	259.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS1_k127_14410597_32	1123242.JH636435_gene1534	1.114e-50	202.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14410597_30	1123253.AUBD01000011_gene2067	1.684e-58	226.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1X4GI@135614|Xanthomonadales	135614|Xanthomonadales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
GDHHQS1_k127_14410597_39	1123368.AUIS01000016_gene2521	7.335e-37	155.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SACF@1236|Gammaproteobacteria,2NBVJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
GDHHQS1_k127_14410597_26	713586.KB900536_gene428	7.578e-65	233.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS1_k127_14410597_15	118005.AWNK01000010_gene361	1.783e-110	374.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS1_k127_14410597_51	331678.Cphamn1_2348	5.968e-21	95.0	COG1862@1|root,COG1862@2|Bacteria,1FE0E@1090|Chlorobi	1090|Chlorobi	U	TIGRFAM preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS1_k127_14410597_23	6412.HelroP154361	8.312e-76	263.0	COG0450@1|root,KOG0852@2759|Eukaryota,38B9P@33154|Opisthokonta,3B9IG@33208|Metazoa,3CS1I@33213|Bilateria	33208|Metazoa	O	Peroxiredoxin	TPX1	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0008379,GO:0009056,GO:0009636,GO:0009987,GO:0010259,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019725,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0051920,GO:0055114,GO:0060548,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K20011	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA,Redoxin
GDHHQS1_k127_14410597_44	1313265.JNIE01000006_gene200	1.711e-28	119.0	COG0735@1|root,COG0735@2|Bacteria,2G44Z@200783|Aquificae	200783|Aquificae	K	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS1_k127_14410597_38	1185876.BN8_03009	1.21e-39	152.0	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,47NQA@768503|Cytophagia	976|Bacteroidetes	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
GDHHQS1_k127_14410597_68	1207075.PputUW4_00144	0.0007327	51.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K07387,ko:K21010	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M48,TPR_1,TPR_11,TPR_19,TPR_8
GDHHQS1_k127_14410597_1	861299.J421_3613	6.802e-291	908.0	COG3808@1|root,COG3808@2|Bacteria,1ZT09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS1_k127_14410597_55	929703.KE386491_gene3786	8.446e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_14410597_63	926550.CLDAP_22710	9.496e-06	60.0	COG0457@1|root,COG0457@2|Bacteria	926550.CLDAP_22710|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14410597_45	1128421.JAGA01000003_gene3091	2.717e-27	130.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS1_k127_14410597_14	656519.Halsa_1650	9.768e-115	380.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3WAA7@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS1_k127_14410597_18	1121468.AUBR01000027_gene2878	9.514e-93	332.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,42ETD@68295|Thermoanaerobacterales	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS1_k127_14410597_35	864565.HMPREF0379_1445	1.746e-46	186.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,25T9S@186804|Peptostreptococcaceae	186801|Clostridia	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
GDHHQS1_k127_14410597_9	1125863.JAFN01000001_gene101	8.874e-133	431.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS1_k127_14410597_54	35760.BCHO_1212	8.001e-12	77.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS1_k127_14410597_47	391037.Sare_1798	1.349e-25	121.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4DCPZ@85008|Micromonosporales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS1_k127_14410597_21	671143.DAMO_2401	4.032e-78	268.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GDHHQS1_k127_14410597_16	8496.XP_006272326.1	3.332e-107	392.0	COG1132@1|root,KOG0055@2759|Eukaryota,38E88@33154|Opisthokonta,3B958@33208|Metazoa,3CVKH@33213|Bilateria,483MS@7711|Chordata,48ZZW@7742|Vertebrata	33208|Metazoa	Q	phosphatidylcholine-translocating ATPase activity	ABCB5	GO:0001654,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006996,GO:0007275,GO:0007423,GO:0008150,GO:0008559,GO:0009987,GO:0010876,GO:0015238,GO:0015399,GO:0015405,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019915,GO:0022804,GO:0022857,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0033036,GO:0042221,GO:0042391,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043226,GO:0043227,GO:0043229,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044840,GO:0044841,GO:0048058,GO:0048513,GO:0048731,GO:0048749,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0097708	3.6.3.44	ko:K05658,ko:K05659,ko:K05660,ko:K05664	ko01522,ko02010,ko04976,ko04979,ko05206,ko05226,map01522,map02010,map04976,map04979,map05206,map05226	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04090,ko04147	3.A.1.201	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_14410597_6	404589.Anae109_1713	5.547e-197	637.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	cytochrome c	ccsBA	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
GDHHQS1_k127_14410597_13	404589.Anae109_1712	1.185e-122	406.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
GDHHQS1_k127_14410597_62	1121440.AUMA01000005_gene2625	3.519e-07	58.0	COG0348@1|root,COG0348@2|Bacteria,1R4WT@1224|Proteobacteria,42NQI@68525|delta/epsilon subdivisions,2WKGR@28221|Deltaproteobacteria,2M7YW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
GDHHQS1_k127_14410597_59	269799.Gmet_2930	2.996e-08	63.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria,42XJ4@68525|delta/epsilon subdivisions,2WSQ4@28221|Deltaproteobacteria,43TRS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS1_k127_14410597_11	671143.DAMO_0825	3.742e-127	431.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	mccA	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
GDHHQS1_k127_14410597_8	671143.DAMO_0826	4.228e-142	469.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrome_C7
GDHHQS1_k127_14410597_7	526227.Mesil_3337	1.211e-180	577.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
GDHHQS1_k127_14410597_56	1173028.ANKO01000064_gene3113	1.323e-10	73.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14,Trypsin_2
GDHHQS1_k127_14410597_52	1220534.B655_0694	2.139e-19	105.0	arCOG06557@1|root,arCOG06557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14410597_67	1120949.KB903295_gene2162	0.000412	55.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4D9AK@85008|Micromonosporales	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36
GDHHQS1_k127_14410597_60	1191523.MROS_1889	3.301e-08	65.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	porV	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14410597_3	1123368.AUIS01000005_gene291	7.664e-207	680.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,2NBW5@225057|Acidithiobacillales	225057|Acidithiobacillales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS1_k127_14410597_58	56110.Oscil6304_0453	1.316e-08	68.0	COG0668@1|root,COG0668@2|Bacteria,1G0CX@1117|Cyanobacteria,1H8K1@1150|Oscillatoriales	1117|Cyanobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
GDHHQS1_k127_14410597_61	592028.GCWU000321_00582	4.006e-08	66.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4H5JY@909932|Negativicutes	909932|Negativicutes	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
GDHHQS1_k127_1455541_12	608538.HTH_1136	1.566e-44	184.0	COG1348@1|root,COG1348@2|Bacteria	2|Bacteria	P	oxidoreductase activity, acting on iron-sulfur proteins as donors	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
GDHHQS1_k127_1455541_30	1316936.K678_14050	3.56e-07	64.0	COG2710@1|root,COG2710@2|Bacteria,1R3ZB@1224|Proteobacteria,2U40A@28211|Alphaproteobacteria,2JVXS@204441|Rhodospirillales	1224|Proteobacteria	C	COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_1455541_29	1123247.AUIJ01000015_gene1335	2.603e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
GDHHQS1_k127_1455541_27	1196029.ALIM01000036_gene1068	3.891e-09	70.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS1_k127_1455541_15	1192034.CAP_3557	5.903e-32	146.0	COG0535@1|root,COG0535@2|Bacteria,1NDTC@1224|Proteobacteria	1224|Proteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_1455541_21	644282.Deba_2506	1.617e-18	102.0	COG0535@1|root,COG0535@2|Bacteria,1ND1B@1224|Proteobacteria,42RQW@68525|delta/epsilon subdivisions,2WNGX@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_1455541_25	1509405.GV67_10245	3.12e-12	77.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria,4BE6J@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_1455541_14	338963.Pcar_0114	7.078e-35	144.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,43S0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS1_k127_1455541_9	1231241.Mc24_01489	1.231e-59	235.0	COG0820@1|root,COG0820@2|Bacteria,2GC4T@200918|Thermotogae	200918|Thermotogae	J	PFAM Radical SAM domain protein	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	-
GDHHQS1_k127_1455541_18	42345.XP_008777423.1	4.355e-24	120.0	COG1535@1|root,2QQB1@2759|Eukaryota,37IJ0@33090|Viridiplantae,3GBAF@35493|Streptophyta,3KNR3@4447|Liliopsida	35493|Streptophyta	Q	Isochorismatase family	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009117,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS1_k127_1455541_0	1123368.AUIS01000008_gene2160	0.0	1133.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,2NCRR@225057|Acidithiobacillales	225057|Acidithiobacillales	F	ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
GDHHQS1_k127_1455541_20	1163617.SCD_n00384	1.3e-20	92.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
GDHHQS1_k127_1455541_7	1123393.KB891316_gene1482	1.059e-77	267.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VQMN@28216|Betaproteobacteria,1KSHY@119069|Hydrogenophilales	119069|Hydrogenophilales	O	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_1455541_23	1470591.BW41_02380	6.363e-15	81.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS1_k127_1455541_13	671143.DAMO_1164	1.907e-35	142.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS1_k127_1455541_17	478741.JAFS01000002_gene875	2.569e-30	131.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS1_k127_1455541_16	926569.ANT_05310	1.104e-31	133.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS1_k127_1455541_2	1173024.KI912148_gene4646	6.398e-160	522.0	COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria,1JI9I@1189|Stigonemataceae	1117|Cyanobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS1_k127_1455541_10	521674.Plim_2955	8.702e-59	230.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS1_k127_1455541_22	926560.KE387025_gene4069	2.113e-16	90.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
GDHHQS1_k127_1455541_31	1530186.JQEY01000010_gene2778	1.73e-05	56.0	COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,2U7IN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
GDHHQS1_k127_1455541_5	1266914.ATUK01000010_gene1484	1.796e-103	363.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1RR7V@1236|Gammaproteobacteria,1WZFV@135613|Chromatiales	135613|Chromatiales	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
GDHHQS1_k127_1455541_19	1123228.AUIH01000008_gene2474	7.192e-22	111.0	COG4939@1|root,COG5274@1|root,COG4939@2|Bacteria,COG5274@2|Bacteria,1NACU@1224|Proteobacteria,1SETD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CI	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
GDHHQS1_k127_1455541_26	1379698.RBG1_1C00001G0853	3.641e-11	72.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1455541_28	316274.Haur_1083	2.016e-08	65.0	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS1_k127_1455541_24	1380394.JADL01000005_gene5355	9.017e-13	82.0	COG0784@1|root,COG0784@2|Bacteria,1NHP4@1224|Proteobacteria,2UWGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_1455541_4	290397.Adeh_0417	5.196e-123	418.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_1455541_11	1121918.ARWE01000001_gene1125	1.883e-45	179.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42NE2@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
GDHHQS1_k127_1455541_32	1235279.C772_01050	2.561e-05	56.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,26CWG@186818|Planococcaceae	91061|Bacilli	K	Sigma-54 factor, Activator interacting domain (AID)	sigL	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GDHHQS1_k127_1455541_3	1125863.JAFN01000001_gene2044	2.336e-155	511.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
GDHHQS1_k127_1455541_1	208444.JNYY01000004_gene2314	1.516e-217	704.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4E0IR@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS1_k127_1455541_8	391735.Veis_1346	1.732e-61	224.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,4AAYE@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
GDHHQS1_k127_1455541_6	1121405.dsmv_1899	6.253e-85	304.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2MIW0@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM pyruvate carboxyltransferase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GDHHQS1_k127_1576965_10	585501.HMPREF6123_0166	0.0001966	52.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,2PS11@265975|Oribacterium	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS1_k127_1576965_1	497964.CfE428DRAFT_3137	1.577e-59	214.0	2AQME@1|root,31FUG@2|Bacteria,46VH0@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1576965_8	452637.Oter_0659	0.0001109	53.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS1_k127_1576965_3	1340493.JNIF01000003_gene4460	7.085e-33	143.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS1_k127_1576965_0	243090.RB12434	2.374e-95	332.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_1576965_2	861299.J421_1748	1.766e-59	230.0	2E4Q1@1|root,32ZIN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1576965_9	930171.Asphe3_37340	0.0001499	55.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,1W8RN@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS1_k127_1576965_5	638303.Thal_1378	1.407e-19	106.0	COG0501@1|root,COG0501@2|Bacteria,2G3RN@200783|Aquificae	200783|Aquificae	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS1_k127_1576965_4	555778.Hneap_1456	1.033e-28	135.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1WWRR@135613|Chromatiales	135613|Chromatiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS1_k127_1576965_6	1530186.JQEY01000008_gene3022	9.492e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1643998_0	941449.dsx2_0858	2.897e-88	301.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2M9EG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS1_k127_1659256_1	344747.PM8797T_14354	1.87e-34	152.0	COG0793@1|root,COG2234@1|root,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
GDHHQS1_k127_1659256_0	1089553.Tph_c04040	1.179e-71	258.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,42F88@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM multi antimicrobial extrusion protein MatE	norM	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS1_k127_1721452_21	1123508.JH636452_gene6936	1.519e-18	98.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_1721452_14	1121438.JNJA01000015_gene1301	5.33e-35	152.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,42VEH@68525|delta/epsilon subdivisions,2WVST@28221|Deltaproteobacteria,2MA0A@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS1_k127_1721452_6	1205680.CAKO01000002_gene2945	3.968e-86	295.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
GDHHQS1_k127_1721452_1	338969.Rfer_1544	6.86e-155	506.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,4AAJR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	pap	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
GDHHQS1_k127_1721452_7	477974.Daud_2151	6.71e-79	275.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,26028@186807|Peptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS1_k127_1721452_4	1121403.AUCV01000009_gene1455	2.774e-93	325.0	COG3899@1|root,COG4191@1|root,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,Pkinase
GDHHQS1_k127_1721452_22	1461693.ATO10_09970	1.639e-14	78.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_1721452_8	1384054.N790_01290	1.071e-76	263.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,1S6M1@1236|Gammaproteobacteria,1XAJC@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
GDHHQS1_k127_1721452_12	653733.Selin_0993	2.174e-52	197.0	COG3169@1|root,COG3169@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
GDHHQS1_k127_1721452_15	1123392.AQWL01000008_gene1245	6.399e-34	131.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GDHHQS1_k127_1721452_2	194439.CT1726	1.051e-144	467.0	COG0701@1|root,COG0701@2|Bacteria,1FDFM@1090|Chlorobi	1090|Chlorobi	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
GDHHQS1_k127_1721452_9	1163617.SCD_n01989	3.252e-74	254.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2VTZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
GDHHQS1_k127_1721452_0	357808.RoseRS_1917	2.28e-155	505.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi,37708@32061|Chloroflexia	32061|Chloroflexia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GDHHQS1_k127_1721452_13	1519464.HY22_09850	2.288e-45	168.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
GDHHQS1_k127_1721452_20	314230.DSM3645_12996	5.57e-19	100.0	COG0640@1|root,COG0640@2|Bacteria,2J12M@203682|Planctomycetes	203682|Planctomycetes	K	transcriptional regulator, ArsR family protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS1_k127_1721452_17	426117.M446_1369	1.75e-28	132.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,1JRBF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
GDHHQS1_k127_1721452_10	378806.STAUR_6137	7.677e-68	248.0	29UQM@1|root,30G2F@2|Bacteria,1NSCX@1224|Proteobacteria,42YNA@68525|delta/epsilon subdivisions,2WTSS@28221|Deltaproteobacteria,2YYJA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1721452_16	69042.WH5701_02269	1.305e-28	125.0	COG0500@1|root,COG2226@2|Bacteria,1G49I@1117|Cyanobacteria,1GZF6@1129|Synechococcus	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
GDHHQS1_k127_1721452_18	1210884.HG799468_gene13815	2.991e-25	118.0	COG1959@1|root,COG1959@2|Bacteria,2J1K3@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS1_k127_1721452_11	102125.Xen7305DRAFT_00030290	8.825e-68	237.0	COG0778@1|root,COG0778@2|Bacteria,1G2KA@1117|Cyanobacteria,3VIH1@52604|Pleurocapsales	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS1_k127_1721452_5	1232410.KI421412_gene357	1.712e-89	315.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,43TDI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS1_k127_1721452_3	1007103.AFHW01000160_gene3089	4.752e-99	336.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
GDHHQS1_k127_1721452_19	760117.JN27_07375	8.633e-21	107.0	292BS@1|root,2ZPW7@2|Bacteria,1REGA@1224|Proteobacteria,2VTQU@28216|Betaproteobacteria,474IK@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1754859_16	518766.Rmar_0066	1.464e-10	73.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1FJ0W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS1_k127_1754859_11	1007103.AFHW01000146_gene5073	3.801e-21	107.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS1_k127_1754859_2	504728.K649_07650	4.653e-68	252.0	COG1136@1|root,COG1136@2|Bacteria,1WJ97@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_1754859_8	1038866.KB902806_gene2454	2.169e-39	165.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,3JUDT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_1754859_7	1121015.N789_08980	6.34e-40	171.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1X4UK@135614|Xanthomonadales	135614|Xanthomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_1754859_0	264462.Bd0888	2.261e-312	1009.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS1_k127_1754859_15	1201288.M900_1458	2.965e-11	76.0	COG1538@1|root,COG1538@2|Bacteria,1Q8XW@1224|Proteobacteria,43EZ7@68525|delta/epsilon subdivisions,2MT8A@213481|Bdellovibrionales,2X2QE@28221|Deltaproteobacteria	213481|Bdellovibrionales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS1_k127_1754859_3	1201290.M902_0803	3.36e-64	239.0	2CH0S@1|root,341IR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1754859_6	638303.Thal_1464	5.404e-54	195.0	COG1898@1|root,COG1898@2|Bacteria,2G3ZK@200783|Aquificae	200783|Aquificae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS1_k127_1754859_1	448385.sce3507	6.924e-82	287.0	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria,2YUF6@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
GDHHQS1_k127_1754859_10	118163.Ple7327_3611	5.355e-24	111.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,3VIPN@52604|Pleurocapsales	1117|Cyanobacteria	KT	PFAM Response regulator receiver domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1754859_14	1463857.JOFZ01000009_gene6207	6.773e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1754859_13	883126.HMPREF9710_04325	5.583e-18	89.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2W90B@28216|Betaproteobacteria,476FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS1_k127_1754859_5	502025.Hoch_4645	2.876e-56	224.0	COG0784@1|root,COG2197@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,Response_reg
GDHHQS1_k127_1754859_4	1242864.D187_001574	4.576e-60	231.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WJRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
GDHHQS1_k127_1754859_9	68219.JNXI01000040_gene5488	2.492e-37	161.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_1754859_12	56107.Cylst_0769	1.19e-18	91.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G027@1117|Cyanobacteria,1HN0K@1161|Nostocales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
GDHHQS1_k127_1768456_5	671143.DAMO_0102	1.09e-44	181.0	COG4772@1|root,COG4772@2|Bacteria,2NRIP@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS1_k127_1768456_0	1333998.M2A_0792	6.872e-230	721.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,4BPEG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	TIGRFAM methylmalonic acid semialdehyde dehydrogenase	mmsA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_1768456_3	1191523.MROS_1572	2.585e-127	413.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
GDHHQS1_k127_1768456_2	1191523.MROS_1571	1.004e-173	559.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
GDHHQS1_k127_1768456_4	1191523.MROS_1570	6.472e-45	172.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
GDHHQS1_k127_1768456_1	1191523.MROS_1569	2.693e-223	707.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS1_k127_1768456_6	880073.Calab_1612	8.443e-19	102.0	COG0509@1|root,COG0745@1|root,COG0509@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
GDHHQS1_k127_1787265_3	265072.Mfla_1137	2.3e-29	135.0	COG0782@1|root,COG0782@2|Bacteria,1RHU5@1224|Proteobacteria,2W3NT@28216|Betaproteobacteria,2KMUI@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM transcription elongation factor GreA GreB	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
GDHHQS1_k127_1787265_2	391625.PPSIR1_29036	1.669e-91	316.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS1_k127_1787265_1	330214.NIDE2085	1.322e-101	367.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
GDHHQS1_k127_1787265_5	204669.Acid345_2517	4.906e-07	64.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
GDHHQS1_k127_1787265_4	526227.Mesil_0932	3.734e-29	133.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1WJKU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
GDHHQS1_k127_1787265_0	330214.NIDE2086	2.84e-136	465.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS1_k127_1791034_0	264462.Bd1798	2.061e-282	899.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MTIN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS1_k127_1791034_8	1184267.A11Q_1741	3.52e-36	154.0	COG1538@1|root,COG1538@2|Bacteria,1PZ5P@1224|Proteobacteria,43EAD@68525|delta/epsilon subdivisions,2MTP2@213481|Bdellovibrionales,2X05F@28221|Deltaproteobacteria	213481|Bdellovibrionales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_1791034_7	1266925.JHVX01000001_gene2645	8.296e-37	146.0	COG1309@1|root,COG1309@2|Bacteria,1NAGX@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS1_k127_1791034_1	926549.KI421517_gene544	9.556e-198	628.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS1_k127_1791034_5	290397.Adeh_4177	1.011e-49	192.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria,2Z3AS@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS1_k127_1791034_2	330214.NIDE3611	2.967e-88	321.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
GDHHQS1_k127_1791034_9	395965.Msil_2208	2.842e-27	128.0	COG1011@1|root,COG1011@2|Bacteria,1Q6A0@1224|Proteobacteria,2V96W@28211|Alphaproteobacteria,3NBWJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS1_k127_1791034_10	401526.TcarDRAFT_2320	6.072e-09	66.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS1_k127_1791034_6	404380.Gbem_1929	5.016e-40	160.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS1_k127_1791034_4	1121920.AUAU01000008_gene1683	1.111e-52	196.0	COG0190@1|root,COG0190@2|Bacteria	2|Bacteria	F	methenyltetrahydrofolate cyclohydrolase activity	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS1_k127_1791034_3	338966.Ppro_1155	5.296e-66	246.0	COG0537@1|root,COG1189@1|root,COG0537@2|Bacteria,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,43S7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS1_k127_1794588_6	384616.Pisl_1913	5.04e-11	63.0	COG0512@1|root,arCOG00086@2157|Archaea,2XQB2@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS1_k127_1794588_5	945713.IALB_2378	7.904e-33	142.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
GDHHQS1_k127_1794588_0	243231.GSU0018	5.308e-148	483.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MID@68525|delta/epsilon subdivisions,2WJYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
GDHHQS1_k127_1794588_7	518766.Rmar_1047	3.822e-08	63.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1FJ8Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS1_k127_1794588_4	502025.Hoch_6859	1.214e-44	183.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS1_k127_1794588_1	1167006.UWK_00713	3.739e-68	238.0	COG2519@1|root,COG2519@2|Bacteria,1QU0A@1224|Proteobacteria,43BUT@68525|delta/epsilon subdivisions,2X75U@28221|Deltaproteobacteria,2MPKK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1794588_3	1293054.HSACCH_01400	6.559e-47	193.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WAHY@53433|Halanaerobiales	186801|Clostridia	T	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_1794588_2	358396.C445_00280	4.739e-49	192.0	COG0665@1|root,arCOG00755@2157|Archaea,2XUM9@28890|Euryarchaeota,23S19@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	solA	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS1_k127_1819198_12	383372.Rcas_3237	8.614e-05	55.0	COG1266@1|root,COG1266@2|Bacteria,2G9RS@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS1_k127_1819198_3	926550.CLDAP_10000	4.21e-74	263.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS1_k127_1819198_2	518766.Rmar_1570	4.045e-85	290.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1FIZF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
GDHHQS1_k127_1819198_11	502025.Hoch_1914	3.817e-13	71.0	297WK@1|root,2ZV33@2|Bacteria,1P83J@1224|Proteobacteria,432YB@68525|delta/epsilon subdivisions,2WYBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1819198_9	1500894.JQNN01000001_gene2441	7.773e-42	162.0	COG4845@1|root,COG4845@2|Bacteria,1NJRF@1224|Proteobacteria,2W22D@28216|Betaproteobacteria,4756T@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Chloramphenicol acetyltransferase	-	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
GDHHQS1_k127_1819198_10	90371.CY43_08355	3.282e-16	92.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,1S0JK@1236|Gammaproteobacteria,3ZMYJ@590|Salmonella	1236|Gammaproteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_1819198_6	1121033.AUCF01000006_gene4228	5.278e-53	209.0	COG0847@1|root,COG0847@2|Bacteria,1RJBK@1224|Proteobacteria,2VF6S@28211|Alphaproteobacteria,2JWMF@204441|Rhodospirillales	204441|Rhodospirillales	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS1_k127_1819198_1	246194.CHY_1909	5.001e-99	349.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,42FQX@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
GDHHQS1_k127_1819198_4	1121468.AUBR01000051_gene1994	6.068e-69	244.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,42G2S@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
GDHHQS1_k127_1819198_0	235985.BBPN01000053_gene7861	1.792e-113	398.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,2NG3I@228398|Streptacidiphilus	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS1_k127_1819198_5	1278078.G419_11792	4.632e-66	255.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4FTX7@85025|Nocardiaceae	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
GDHHQS1_k127_1819198_8	215803.DB30_0743	3.049e-44	181.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
GDHHQS1_k127_1819198_7	1267533.KB906738_gene2257	2.587e-46	171.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS1_k127_1841401_1	582515.KR51_00011900	4.432e-05	55.0	COG0658@1|root,COG0658@2|Bacteria,1G11N@1117|Cyanobacteria	1117|Cyanobacteria	S	ComEC Rec2-related protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
GDHHQS1_k127_1841401_0	1123257.AUFV01000012_gene2983	2.242e-63	221.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS1_k127_1844291_20	1463841.JOIR01000014_gene1313	2.053e-08	63.0	COG2931@1|root,COG2931@2|Bacteria,2GXH3@201174|Actinobacteria	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1844291_15	1303518.CCALI_02281	6.705e-26	113.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1844291_21	1500897.JQNA01000001_gene5599	2.65e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,1KGHM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_1844291_13	1184267.A11Q_1873	2.794e-43	168.0	COG3619@1|root,COG3619@2|Bacteria,1PGVP@1224|Proteobacteria,437KI@68525|delta/epsilon subdivisions,2MU1E@213481|Bdellovibrionales,2X2UM@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
GDHHQS1_k127_1844291_17	429009.Adeg_1940	6.708e-15	79.0	COG0640@1|root,COG0640@2|Bacteria,1V6CU@1239|Firmicutes,24R9E@186801|Clostridia,42H4C@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS1_k127_1844291_1	525904.Tter_0485	3.303e-122	414.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS1_k127_1844291_16	553184.ATORI0001_0777	9.718e-19	91.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4CVTV@84998|Coriobacteriia	84998|Coriobacteriia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
GDHHQS1_k127_1844291_0	378806.STAUR_5873	3.311e-132	433.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YUQY@29|Myxococcales	28221|Deltaproteobacteria	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS1_k127_1844291_3	378806.STAUR_5874	1.495e-106	360.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria,438QP@68525|delta/epsilon subdivisions,2X92A@28221|Deltaproteobacteria,2YXIK@29|Myxococcales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF1611_C) P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
GDHHQS1_k127_1844291_7	290397.Adeh_0171	7.024e-80	282.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS1_k127_1844291_6	518766.Rmar_0947	1.38e-94	326.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_1844291_9	1121920.AUAU01000010_gene43	1.032e-75	274.0	COG0078@1|root,COG0078@2|Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.3,2.1.3.9	ko:K00611,ko:K09065,ko:K13043	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS1_k127_1844291_10	589924.Ferp_2236	8.15e-72	267.0	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,245SQ@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS1_k127_1844291_8	378806.STAUR_5871	1.761e-76	281.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria,2YY4J@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS1_k127_1844291_5	378806.STAUR_5872	3.236e-96	336.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
GDHHQS1_k127_1844291_14	1121396.KB893077_gene747	6.287e-33	137.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
GDHHQS1_k127_1844291_18	1122915.AUGY01000035_gene1041	4.021e-12	79.0	COG1404@1|root,COG1404@2|Bacteria,1UGHG@1239|Firmicutes,4HC8T@91061|Bacilli,26TIJ@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
GDHHQS1_k127_1844291_4	401526.TcarDRAFT_1800	8.664e-103	359.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS1_k127_1844291_19	411154.GFO_1672	1.32e-11	73.0	29FE7@1|root,302BX@2|Bacteria,4NMTG@976|Bacteroidetes,1I1WT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1844291_12	215803.DB30_0944	4.477e-59	227.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_1844291_2	1232410.KI421422_gene1997	1.394e-110	380.0	28HGQ@1|root,2Z7SH@2|Bacteria,1R6PH@1224|Proteobacteria,42NK0@68525|delta/epsilon subdivisions,2WMHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1844291_11	1307761.L21SP2_2601	1.383e-65	253.0	28JYD@1|root,2Z9NN@2|Bacteria	1307761.L21SP2_2601|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2160344_7	1123242.JH636435_gene1534	7.168e-28	119.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2160344_5	234267.Acid_0104	4.059e-61	235.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_2160344_14	1238182.C882_3875	1.794e-07	61.0	2EJPN@1|root,33DEG@2|Bacteria,1NJ0G@1224|Proteobacteria,2UKKF@28211|Alphaproteobacteria,2JUH8@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2160344_8	1502770.JQMG01000001_gene815	6.233e-27	117.0	COG2114@1|root,COG2114@2|Bacteria,1PZ5K@1224|Proteobacteria,2W3A8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS1_k127_2160344_2	1035191.HMPREF0185_02589	1.401e-99	364.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_2160344_3	861299.J421_6133	2.282e-77	268.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	dcsG	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,RimK
GDHHQS1_k127_2160344_11	292459.STH932	2.255e-17	84.0	COG1942@1|root,COG1942@2|Bacteria,1VGNJ@1239|Firmicutes,24QU3@186801|Clostridia	186801|Clostridia	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
GDHHQS1_k127_2160344_12	301.JNHE01000001_gene179	2.282e-17	87.0	COG2197@1|root,COG2199@1|root,COG2197@2|Bacteria,COG3706@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1YHQP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	luxR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_2160344_13	1123371.ATXH01000018_gene1364	4.638e-16	84.0	COG0484@1|root,COG0484@2|Bacteria,2GIGH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	DnaJ central domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS1_k127_2160344_6	1297742.A176_01710	1.499e-32	146.0	COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria,42S0W@68525|delta/epsilon subdivisions,2WVDD@28221|Deltaproteobacteria,2YU0R@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GDHHQS1_k127_2160344_4	1089548.KI783301_gene2548	1.6e-71	261.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli	91061|Bacilli	Q	synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GDHHQS1_k127_2160344_9	671143.DAMO_0701	1.458e-26	118.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
GDHHQS1_k127_2160344_10	264732.Moth_1608	9.479e-18	93.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
GDHHQS1_k127_2160344_0	649638.Trad_0638	5.226e-223	705.0	COG1132@1|root,COG1132@2|Bacteria,1WMBB@1297|Deinococcus-Thermus	2|Bacteria	V	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_2160344_1	1313301.AUGC01000012_gene1383	6.386e-199	629.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS1_k127_2161130_3	195253.Syn6312_2136	2.656e-72	249.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1GZFE@1129|Synechococcus	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
GDHHQS1_k127_2161130_1	1111069.TCCBUS3UF1_16380	2.042e-183	585.0	COG0473@1|root,COG0473@2|Bacteria,1WIRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS1_k127_2161130_0	1379270.AUXF01000003_gene3536	4.417e-209	665.0	COG0281@1|root,COG0281@2|Bacteria,1ZUM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
GDHHQS1_k127_2161130_2	383372.Rcas_4255	6.782e-150	487.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS1_k127_2161130_4	471857.Svir_04190	1.221e-23	118.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4DXX8@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0000166,GO:0003674,GO:0003824,GO:0004017,GO:0004550,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006165,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009141,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032261,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043173,GO:0044209,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
GDHHQS1_k127_2161130_5	3847.GLYMA16G06250.1	2.793e-11	78.0	COG0572@1|root,KOG4203@2759|Eukaryota,37MJC@33090|Viridiplantae,3GE4G@35493|Streptophyta,4JS3E@91835|fabids	35493|Streptophyta	F	Belongs to the uridine kinase family	-	GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006109,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0010138,GO:0010675,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0032262,GO:0032881,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043173,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044206,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2000904	2.7.1.48,5.1.3.1	ko:K00876,ko:K01783	ko00030,ko00040,ko00240,ko00710,ko00983,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00240,map00710,map00983,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01529,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017,RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK,UPRTase
GDHHQS1_k127_2193318_6	335543.Sfum_0188	2.744e-08	66.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS1_k127_2193318_5	56780.SYN_00415	2.032e-26	126.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS1_k127_2193318_4	639282.DEFDS_1505	9.196e-30	135.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
GDHHQS1_k127_2193318_1	1144313.PMI10_02732	1.711e-93	320.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Alpha_L_fucos,Cellulase,RicinB_lectin_2
GDHHQS1_k127_2193318_3	1254432.SCE1572_22375	2.848e-47	195.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2193318_0	498761.HM1_0969	3.619e-126	413.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS1_k127_2193318_2	518766.Rmar_2557	4.295e-71	255.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1FJUI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS1_k127_2193318_7	1123320.KB889618_gene7004	0.0004444	48.0	2E3SC@1|root,32YPX@2|Bacteria,2GQRK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
GDHHQS1_k127_2205696_1	247490.KSU1_B0397	9.171e-97	323.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
GDHHQS1_k127_2205696_0	864702.OsccyDRAFT_3833	1.614e-137	447.0	COG0436@1|root,COG0436@2|Bacteria,1G24E@1117|Cyanobacteria,1H6X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS1_k127_2389841_2	429009.Adeg_0440	1.144e-30	124.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42F1S@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
GDHHQS1_k127_2389841_3	390989.JOEG01000028_gene5474	1.138e-13	72.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4D9DW@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS1_k127_2389841_0	251221.35211733	1.456e-103	346.0	COG0837@1|root,COG0837@2|Bacteria,1G1TJ@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
GDHHQS1_k127_2389841_1	1384056.N787_01740	1.511e-43	163.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1X5RU@135614|Xanthomonadales	135614|Xanthomonadales	G	COG3957 Phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
GDHHQS1_k127_2413116_0	1173024.KI912153_gene315	0.0	1119.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GDHHQS1_k127_2413116_2	1396141.BATP01000007_gene5666	1.091e-36	142.0	COG0509@1|root,COG0509@2|Bacteria,46VKU@74201|Verrucomicrobia,2IUJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS1_k127_2413116_1	1111479.AXAR01000003_gene1653	4.195e-107	358.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,277WD@186823|Alicyclobacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS1_k127_2413116_4	1047013.AQSP01000073_gene1092	4.355e-08	65.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
GDHHQS1_k127_2413116_5	1547437.LL06_10255	0.000154	54.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria,43IJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
GDHHQS1_k127_2413116_6	653733.Selin_1273	0.0008226	51.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
GDHHQS1_k127_2413116_3	886293.Sinac_1537	8.1e-19	98.0	COG1073@1|root,COG1073@2|Bacteria,2IZ53@203682|Planctomycetes	203682|Planctomycetes	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2048,Peptidase_S9
GDHHQS1_k127_2477111_18	398767.Glov_0523	5.584e-19	87.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43SVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	metallopeptidase activity	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS1_k127_2477111_13	243164.DET0620	3.862e-49	190.0	COG2887@1|root,COG2887@2|Bacteria,2GBU9@200795|Chloroflexi,34CT2@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
GDHHQS1_k127_2477111_8	869210.Marky_0660	5.18e-84	299.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS1_k127_2477111_15	756883.Halar_2845	9.304e-41	168.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838,ko:K07025	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS1_k127_2477111_4	330214.NIDE3036	5.013e-122	427.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_2477111_1	264732.Moth_1955	2.868e-152	490.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_2477111_19	1232410.KI421428_gene1129	1.038e-13	77.0	COG2050@1|root,COG2050@2|Bacteria,1NHB0@1224|Proteobacteria,42XCC@68525|delta/epsilon subdivisions,2WTEP@28221|Deltaproteobacteria,43UMX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS1_k127_2477111_6	1340493.JNIF01000004_gene761	6.102e-111	368.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS1_k127_2477111_21	443144.GM21_1524	1.845e-06	60.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HAMP,HATPase_c,HisKA
GDHHQS1_k127_2477111_0	204669.Acid345_1381	1.406e-179	596.0	COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85	ko:K00128,ko:K00130,ko:K00146,ko:K10217	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00555,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_2477111_9	1519464.HY22_11400	3.549e-78	275.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	paaF	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692,ko:K01715,ko:K07534	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01220,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212,map01220	M00032,M00087,M00540	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R05600,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02034,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS1_k127_2477111_12	926554.KI912633_gene3902	6.518e-66	234.0	COG1024@1|root,COG1024@2|Bacteria,1WIYN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Enoyl-CoA hydratase isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS1_k127_2477111_11	862908.BMS_2002	1.185e-69	248.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,43187@68525|delta/epsilon subdivisions,2WWG4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GDHHQS1_k127_2477111_22	639030.JHVA01000001_gene1087	1.003e-05	59.0	COG1807@1|root,COG1807@2|Bacteria,3Y3EH@57723|Acidobacteria,2JHRT@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_2477111_5	391625.PPSIR1_39700	6.605e-116	390.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2Z1PP@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_14,TPR_16
GDHHQS1_k127_2477111_10	710696.Intca_0237	3.682e-74	262.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria,4FF7A@85021|Intrasporangiaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS1_k127_2477111_16	483219.LILAB_21020	9.71e-39	153.0	COG0546@1|root,COG0546@2|Bacteria,1P19B@1224|Proteobacteria,431NT@68525|delta/epsilon subdivisions,2WWU8@28221|Deltaproteobacteria,2YVRG@29|Myxococcales	28221|Deltaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2477111_20	1242864.D187_006059	3.839e-11	75.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria,2YTVI@29|Myxococcales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	glp	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
GDHHQS1_k127_2477111_3	1005048.CFU_4087	2.6e-123	415.0	COG1502@1|root,COG1502@2|Bacteria,1R9I4@1224|Proteobacteria,2W1UK@28216|Betaproteobacteria,475D4@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS1_k127_2477111_17	634500.EbC_22050	1.621e-34	140.0	COG1357@1|root,COG1357@2|Bacteria,1REAS@1224|Proteobacteria,1S4BN@1236|Gammaproteobacteria,3X5IM@551|Erwinia	1236|Gammaproteobacteria	S	Pentapeptide repeats (8 copies)	mcbG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
GDHHQS1_k127_2477111_14	1379698.RBG1_1C00001G0525	5.716e-45	170.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS1_k127_2477111_2	867903.ThesuDRAFT_01199	3.826e-125	421.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,3WCDU@538999|Clostridiales incertae sedis	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS1_k127_2477111_7	290397.Adeh_1825	1.364e-92	320.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,2YU5E@29|Myxococcales	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS1_k127_2477613_7	1121930.AQXG01000002_gene2352	0.0001563	59.0	COG2373@1|root,COG2755@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4412@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2755@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	pelX	-	-	ko:K07004,ko:K09955,ko:K16915,ko:K20276	ko02010,ko02024,map02010,map02024	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	Beta_helix,Laminin_G_3
GDHHQS1_k127_2477613_8	985054.JQEZ01000003_gene1209	0.0006145	57.0	COG2373@1|root,COG2373@2|Bacteria,1QV7E@1224|Proteobacteria,2TWCD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
GDHHQS1_k127_2477613_5	710111.FraQA3DRAFT_4565	2.514e-13	84.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4EU82@85013|Frankiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	ko:K14371	ko00522,ko01052,ko01130,map00522,map01052,map01130	M00777	R06480,R06481,R06482,R06483	RC00004,RC02913,RC02914,RC02915,RC02920,RC02921,RC02922,RC02923,RC02924,RC02925,RC02926,RC02927,RC02928,RC02929,RC02930	ko00000,ko00001,ko00002,ko01008	-	-	-	ADH_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
GDHHQS1_k127_2477613_4	449447.MAE_07890	3.071e-22	108.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14
GDHHQS1_k127_2477613_3	330214.NIDE1116	9.041e-89	318.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,3J0XC@40117|Nitrospirae	40117|Nitrospirae	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS1_k127_2477613_6	393921.HQ45_07090	3.952e-05	54.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,2FU0X@200643|Bacteroidia,22YDQ@171551|Porphyromonadaceae	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
GDHHQS1_k127_2477613_2	1123253.AUBD01000008_gene522	1.733e-131	429.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1X3A8@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS1_k127_2477613_1	1267533.KB906737_gene1703	1.981e-141	465.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GDHHQS1_k127_2477613_0	941824.TCEL_01674	2.486e-256	800.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,36DK8@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS1_k127_2532917_6	66377.JOBH01000010_gene6302	8.256e-14	87.0	COG2232@1|root,COG2232@2|Bacteria,2I3K8@201174|Actinobacteria	201174|Actinobacteria	S	ATP-grasp domain	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-grasp_4
GDHHQS1_k127_2532917_7	1396418.BATQ01000099_gene5575	1.32e-05	56.0	COG0388@1|root,COG0388@2|Bacteria,46ZGG@74201|Verrucomicrobia,2IUQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
GDHHQS1_k127_2532917_3	2074.JNYD01000002_gene5627	5.396e-91	337.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
GDHHQS1_k127_2532917_2	511.JT27_01790	2.543e-103	344.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,2VKKW@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	-	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
GDHHQS1_k127_2532917_8	1365176.N186_04110	8.203e-05	51.0	COG3620@1|root,arCOG00608@2157|Archaea,2XR1X@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_3
GDHHQS1_k127_2532917_5	643867.Ftrac_0814	5.773e-24	109.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
GDHHQS1_k127_2532917_1	497964.CfE428DRAFT_0142	1.899e-122	400.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_2532917_0	497964.CfE428DRAFT_0143	1.948e-137	449.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_2532917_4	404380.Gbem_0528	8.738e-44	162.0	COG1917@1|root,COG1917@2|Bacteria,1RKTY@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2619038_15	649638.Trad_2703	1.491e-53	194.0	COG0167@1|root,COG0167@2|Bacteria,1WI2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS1_k127_2619038_5	370438.PTH_1811	2.516e-129	426.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS1_k127_2619038_11	1144275.COCOR_04532	2.763e-95	321.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2YU78@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS1_k127_2619038_18	1121380.JNIW01000122_gene310	9.33e-26	115.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2619038_6	1104325.M7W_2556	5.637e-116	409.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,4AZ66@81852|Enterococcaceae	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS1_k127_2619038_12	316274.Haur_1661	1.909e-71	266.0	COG2962@1|root,COG2962@2|Bacteria,2G6C2@200795|Chloroflexi,375DH@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM RarD protein, DMT superfamily transporter	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
GDHHQS1_k127_2619038_9	477974.Daud_1972	1.757e-100	349.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,24ASU@186801|Clostridia,263XJ@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
GDHHQS1_k127_2619038_16	55601.VANGNB10_cI0062c	9.723e-52	204.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XUDA@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS1_k127_2619038_7	1278073.MYSTI_03388	1.826e-104	376.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
GDHHQS1_k127_2619038_10	401526.TcarDRAFT_1563	4.743e-100	355.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_2619038_4	1144275.COCOR_01049	1.151e-155	503.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2YTTF@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
GDHHQS1_k127_2619038_22	391625.PPSIR1_03713	1.733e-11	79.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19693	-	-	-	-	ko00000,ko03000	-	-	-	CHAP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg
GDHHQS1_k127_2619038_2	404589.Anae109_4136	1.83e-179	589.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2Z33Y@29|Myxococcales	28221|Deltaproteobacteria	M	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GDHHQS1_k127_2619038_13	765420.OSCT_0338	1.394e-70	271.0	COG0047@1|root,COG0047@2|Bacteria,2G6R9@200795|Chloroflexi,374TW@32061|Chloroflexia	32061|Chloroflexia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GDHHQS1_k127_2619038_0	1210884.HG799468_gene13832	4.747e-252	809.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
GDHHQS1_k127_2619038_20	255470.cbdbA325	2.205e-15	85.0	COG0046@1|root,COG0046@2|Bacteria,2G5Z1@200795|Chloroflexi,34CNB@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
GDHHQS1_k127_2619038_8	479434.Sthe_1292	1.312e-101	339.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS1_k127_2619038_1	648996.Theam_0171	1.376e-197	645.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G3NT@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
GDHHQS1_k127_2619038_3	1156937.MFUM_1020090	1.732e-165	529.0	COG0516@1|root,COG0516@2|Bacteria,46W51@74201|Verrucomicrobia,37FWR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GDHHQS1_k127_2619038_19	177437.HRM2_02420	3.762e-18	88.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_2619038_21	1123070.KB899258_gene1881	1.874e-13	76.0	COG0745@1|root,COG0745@2|Bacteria	1123070.KB899258_gene1881|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2619038_14	1385517.N800_01695	1.453e-58	226.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X3H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS1_k127_2619038_17	667014.Thein_1119	4.35e-29	120.0	2A6WD@1|root,30VR5@2|Bacteria,2GIJI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
GDHHQS1_k127_2619038_23	1112204.GPOL_c13690	2.573e-08	63.0	2EGD2@1|root,33A4V@2|Bacteria,2GWY9@201174|Actinobacteria,4GECV@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
GDHHQS1_k127_2643122_1	1410665.JNKR01000033_gene1579	6.338e-12	65.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H2Z8@909932|Negativicutes	909932|Negativicutes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS1_k127_2643122_0	243231.GSU3369	3.425e-114	385.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,43S0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS1_k127_2675630_0	713586.KB900536_gene354	1.14e-52	189.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS1_k127_2675630_2	1288963.ADIS_2783	5.579e-28	133.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
GDHHQS1_k127_2675630_1	671143.DAMO_1093	8.252e-29	125.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
GDHHQS1_k127_2675630_4	448385.sce4251	4.635e-09	63.0	COG0848@1|root,COG0848@2|Bacteria,1Q1RQ@1224|Proteobacteria,437EZ@68525|delta/epsilon subdivisions,2X2MA@28221|Deltaproteobacteria,2Z03D@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS1_k127_2675630_3	485915.Dret_1587	5.051e-13	81.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MC0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS1_k127_2675630_6	398578.Daci_4622	3.397e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,4AD9Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS1_k127_2675630_5	1123274.KB899421_gene1813	1.324e-06	61.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
GDHHQS1_k127_2868824_21	1511.CLOST_0903	2.295e-10	64.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,25QPW@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	ywdH	-	1.2.1.3,1.2.1.9,1.2.99.10	ko:K00128,ko:K00131,ko:K22445	ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00135,M00308,M00633	R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_2868824_11	644282.Deba_2003	1.023e-34	146.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS1_k127_2868824_13	335541.Swol_0338	1.761e-28	132.0	COG1235@1|root,COG1235@2|Bacteria,1VE5M@1239|Firmicutes,24JNF@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS1_k127_2868824_18	997884.HMPREF1068_00171	9.886e-14	85.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NG0B@976|Bacteroidetes,2FM88@200643|Bacteroidia,4AMAH@815|Bacteroidaceae	2|Bacteria	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
GDHHQS1_k127_2868824_14	926561.KB900623_gene720	8.544e-28	130.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WAQE@53433|Halanaerobiales	186801|Clostridia	L	PFAM Conserved	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS1_k127_2868824_15	1380390.JIAT01000009_gene2013	1.191e-26	123.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS1_k127_2868824_24	414684.RC1_2959	1.459e-05	53.0	COG1396@1|root,COG1396@2|Bacteria,1PYF8@1224|Proteobacteria,2VC0D@28211|Alphaproteobacteria,2JYFR@204441|Rhodospirillales	204441|Rhodospirillales	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2868824_12	1231190.NA8A_03545	1.389e-31	139.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43IGX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS1_k127_2868824_22	187272.Mlg_1872	4.712e-07	60.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GDHHQS1_k127_2868824_9	502025.Hoch_2046	2.755e-79	279.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2Z35Q@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GDHHQS1_k127_2868824_5	530564.Psta_1309	2.369e-128	448.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,2IWV8@203682|Planctomycetes	203682|Planctomycetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,RNase_H_2
GDHHQS1_k127_2868824_8	1123508.JH636440_gene2642	3.957e-82	291.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,2IZV4@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS1_k127_2868824_10	365046.Rta_31020	6.948e-38	150.0	COG0784@1|root,COG0784@2|Bacteria,1QZE2@1224|Proteobacteria,2VU92@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_2868824_23	644966.Tmar_0093	4.154e-06	53.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3WDF1@538999|Clostridiales incertae sedis	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
GDHHQS1_k127_2868824_17	351160.RCIX1181	4.59e-19	95.0	COG0586@1|root,arCOG03117@2157|Archaea,2XXX4@28890|Euryarchaeota	28890|Euryarchaeota	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS1_k127_2868824_2	1499967.BAYZ01000156_gene567	4.868e-180	577.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NMO
GDHHQS1_k127_2868824_1	338966.Ppro_3101	0.0	1725.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,43W01@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
GDHHQS1_k127_2868824_20	768670.Calni_0858	6.68e-13	79.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CarbopepD_reg_2,DUF4384,NPCBM,Plug,SBBP
GDHHQS1_k127_2868824_0	886293.Sinac_3637	0.0	2128.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
GDHHQS1_k127_2868824_4	443143.GM18_2130	5.679e-129	420.0	COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,42PE7@68525|delta/epsilon subdivisions,2WJZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH-3	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
GDHHQS1_k127_2868824_7	404380.Gbem_2101	1.302e-95	322.0	COG2267@1|root,COG2267@2|Bacteria,1QUW0@1224|Proteobacteria,43CDS@68525|delta/epsilon subdivisions,2X7PQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
GDHHQS1_k127_2868824_3	398767.Glov_2271	2.234e-158	518.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,43S9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	iAF987.Gmet_2229	AMP-binding,AMP-binding_C
GDHHQS1_k127_2868824_6	338966.Ppro_3118	2.752e-122	401.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-Beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
GDHHQS1_k127_2868824_16	8128.ENSONIP00000006792	7.438e-20	102.0	COG5479@1|root,2S2KY@2759|Eukaryota,3A1DX@33154|Opisthokonta,3BS3D@33208|Metazoa,3D8FQ@33213|Bilateria,48QFP@7711|Chordata,49M1R@7742|Vertebrata,4A42R@7898|Actinopterygii	33208|Metazoa	T	Peptidoglycan-recognition protein SC2-like	PGLYRP1	GO:0000270,GO:0001775,GO:0001817,GO:0001818,GO:0001906,GO:0002218,GO:0002221,GO:0002225,GO:0002237,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002699,GO:0002700,GO:0002702,GO:0002757,GO:0002758,GO:0002759,GO:0002760,GO:0002764,GO:0002784,GO:0002786,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002816,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006963,GO:0006965,GO:0007154,GO:0007165,GO:0007166,GO:0008063,GO:0008144,GO:0008150,GO:0008152,GO:0008329,GO:0008592,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0012505,GO:0016019,GO:0016045,GO:0016192,GO:0016787,GO:0016810,GO:0016811,GO:0019222,GO:0019730,GO:0023051,GO:0023052,GO:0023056,GO:0030139,GO:0030141,GO:0030203,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031341,GO:0031343,GO:0031347,GO:0031348,GO:0031349,GO:0031410,GO:0031640,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032103,GO:0032494,GO:0032500,GO:0032649,GO:0032689,GO:0032814,GO:0032815,GO:0032823,GO:0032824,GO:0032826,GO:0032827,GO:0032940,GO:0033218,GO:0034248,GO:0034250,GO:0034774,GO:0035580,GO:0035821,GO:0036230,GO:0038023,GO:0038187,GO:0040007,GO:0042119,GO:0042221,GO:0042268,GO:0042277,GO:0042581,GO:0042742,GO:0042749,GO:0042752,GO:0042834,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0043900,GO:0043902,GO:0044110,GO:0044116,GO:0044117,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045087,GO:0045088,GO:0045089,GO:0045187,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045752,GO:0045824,GO:0045919,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050830,GO:0050865,GO:0050866,GO:0050896,GO:0051093,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051249,GO:0051250,GO:0051606,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051712,GO:0051714,GO:0051716,GO:0060089,GO:0060205,GO:0061783,GO:0061844,GO:0065007,GO:0070013,GO:0070820,GO:0071682,GO:0071704,GO:0080134,GO:0097013,GO:0097367,GO:0097708,GO:0098542,GO:0098543,GO:0098581,GO:0099503,GO:1900424,GO:1900426,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901700,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:1904724,GO:2000026	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2
GDHHQS1_k127_2868824_19	751994.AGIG01000007_gene1299	1.579e-13	79.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,1J66I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	fkpB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GDHHQS1_k127_297380_10	391615.ABSJ01000042_gene2206	3.107e-45	166.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1J5JF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS1_k127_297380_17	555793.WSK_1152	9.835e-17	91.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,2UBFT@28211|Alphaproteobacteria,2KCGR@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
GDHHQS1_k127_297380_0	1094715.CM001373_gene272	2.282e-201	636.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1JCSD@118969|Legionellales	118969|Legionellales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS1_k127_297380_14	1121918.ARWE01000001_gene3198	8.237e-26	122.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DFM@68525|delta/epsilon subdivisions,2X8MI@28221|Deltaproteobacteria,43UST@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS1_k127_297380_5	652103.Rpdx1_2614	1.51e-94	328.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3JVIJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS1_k127_297380_9	679926.Mpet_0918	9.163e-49	185.0	COG0134@1|root,arCOG01088@2157|Archaea,2XTWK@28890|Euryarchaeota,2N9V0@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3621	IGPS
GDHHQS1_k127_297380_16	1267535.KB906767_gene286	1.396e-21	102.0	COG0135@1|root,COG0135@2|Bacteria,3Y50K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS1_k127_297380_13	1158756.AQXQ01000009_gene1028	3.579e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ1Y@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS1_k127_297380_1	380394.Lferr_1727	1.016e-149	495.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,2NCFD@225057|Acidithiobacillales	225057|Acidithiobacillales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS1_k127_297380_8	1121013.P873_09345	4.988e-54	206.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1X40W@135614|Xanthomonadales	135614|Xanthomonadales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS1_k127_297380_2	290397.Adeh_4059	7.37e-121	396.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2YXNS@29|Myxococcales	28221|Deltaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
GDHHQS1_k127_297380_4	264732.Moth_1332	5.034e-106	376.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,42ER2@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS1_k127_297380_12	497321.C664_17992	5.21e-41	162.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,2KUFF@206389|Rhodocyclales	206389|Rhodocyclales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
GDHHQS1_k127_297380_3	370438.PTH_1130	1.329e-116	386.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS1_k127_297380_15	869210.Marky_1544	2.315e-24	117.0	COG0703@1|root,COG0703@2|Bacteria,1WI00@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
GDHHQS1_k127_297380_7	1469245.JFBG01000054_gene2111	1.104e-61	232.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS1_k127_297380_11	479437.Elen_2547	8.837e-45	181.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CVUU@84998|Coriobacteriia	84998|Coriobacteriia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II,PTS_EIIB
GDHHQS1_k127_297380_6	518766.Rmar_1042	3.53e-82	290.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1FIRE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS1_k127_297380_18	697329.Rumal_1716	1.146e-07	59.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WHFS@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS1_k127_3035419_2	1379698.RBG1_1C00001G0655	1.112e-197	632.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
GDHHQS1_k127_3035419_37	665571.STHERM_c20850	2.874e-19	93.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
GDHHQS1_k127_3035419_1	1242864.D187_004550	8.491e-228	720.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
GDHHQS1_k127_3035419_22	398767.Glov_3037	3.119e-37	150.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
GDHHQS1_k127_3035419_9	1095769.CAHF01000011_gene2479	2.007e-111	365.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2VH6T@28216|Betaproteobacteria,473WD@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
GDHHQS1_k127_3035419_18	1122611.KB903974_gene3026	6.043e-46	190.0	COG1506@1|root,COG1506@2|Bacteria,2I6NU@201174|Actinobacteria,4EI10@85012|Streptosporangiales	201174|Actinobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	3HBOH,Tannase
GDHHQS1_k127_3035419_10	1121957.ATVL01000007_gene1831	6.524e-104	344.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS1_k127_3035419_7	1379698.RBG1_1C00001G1458	6.947e-117	390.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS1_k127_3035419_0	1167006.UWK_02786	1.685e-235	740.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS1_k127_3035419_27	1444712.BN1013_00282	8.23e-31	138.0	COG0546@1|root,COG0546@2|Bacteria,2JG2T@204428|Chlamydiae	204428|Chlamydiae	S	Protein of unknown function (DUF2608)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2608
GDHHQS1_k127_3035419_12	1278073.MYSTI_01992	1.913e-87	295.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2YX8R@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_3035419_68	1116232.AHBF01000006_gene1684	0.0006993	48.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS1_k127_3035419_16	1144275.COCOR_01564	8.351e-56	206.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS1_k127_3035419_6	1297742.A176_05942	3.425e-121	416.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2YZ59@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_3035419_4	483219.LILAB_14525	4.096e-161	522.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YYF2@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_3035419_3	378806.STAUR_1586	5.335e-170	549.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YYMR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS1_k127_3035419_5	1242864.D187_005843	1.367e-135	451.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria,2YX29@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_3035419_65	1238450.VIBNISOn1_1070042	0.0002859	50.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1SKDR@1236|Gammaproteobacteria,1XUHM@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
GDHHQS1_k127_3035419_57	1499683.CCFF01000014_gene3895	2.361e-06	58.0	2DM46@1|root,31NAS@2|Bacteria,1UKK8@1239|Firmicutes	1239|Firmicutes	S	Siphovirus protein of unknown function (DUF859)	-	-	-	-	-	-	-	-	-	-	-	-	DUF859
GDHHQS1_k127_3035419_43	391625.PPSIR1_01949	7.036e-15	85.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	mftB	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_15	404589.Anae109_0906	4.774e-67	251.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS1_k127_3035419_32	1192034.CAP_3557	4.742e-23	113.0	COG0535@1|root,COG0535@2|Bacteria,1NDTC@1224|Proteobacteria	1224|Proteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_24	391625.PPSIR1_25656	1.184e-33	145.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2WWQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
GDHHQS1_k127_3035419_30	450851.PHZ_c2419	2.59e-26	120.0	COG0535@1|root,COG0535@2|Bacteria,1ND1B@1224|Proteobacteria,2TV8F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_35	391625.PPSIR1_25641	3.855e-20	105.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_13	1506583.JQJY01000004_gene2829	1.578e-85	294.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia,2NVMW@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS1_k127_3035419_8	391625.PPSIR1_25641	2.118e-112	385.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_11	1192034.CAP_2187	6.485e-102	349.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_40	1342299.Z947_1496	9.722e-17	94.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_38	649747.HMPREF0083_04295	3.384e-18	98.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HCG2@91061|Bacilli,26TIW@186822|Paenibacillaceae	91061|Bacilli	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_3035419_29	1463858.JOHR01000012_gene2281	1.277e-26	128.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS1_k127_3035419_59	1489678.RDMS_09145	5.014e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1WJSM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS1_k127_3035419_39	153948.NAL212_0402	1.802e-17	98.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VIK6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	biosynthesis protein E	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_3035419_26	68260.JOAY01000012_gene2924	1.815e-31	141.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_3035419_56	1496688.ER33_12875	1.047e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria,22S8T@167375|Cyanobium	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
GDHHQS1_k127_3035419_17	68260.JOAY01000012_gene2924	5.982e-47	188.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_3035419_60	913325.N799_02970	1.735e-05	58.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1X5KW@135614|Xanthomonadales	135614|Xanthomonadales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_16,TPR_19
GDHHQS1_k127_3035419_64	1041147.AUFB01000017_gene1099	8.171e-05	56.0	COG0457@1|root,COG5653@1|root,COG0457@2|Bacteria,COG5653@2|Bacteria,1R4QD@1224|Proteobacteria,2TU36@28211|Alphaproteobacteria,4BDJ9@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_3035419_61	1169161.KB897740_gene2239	2.712e-05	58.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	1169161.KB897740_gene2239|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_46	1499498.EV05_0003	1.012e-12	82.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1MKWK@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
GDHHQS1_k127_3035419_25	1303518.CCALI_01361	1.7e-32	137.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
GDHHQS1_k127_3035419_52	1306174.JODP01000013_gene7571	8.841e-08	65.0	COG0457@1|root,COG0457@2|Bacteria	1306174.JODP01000013_gene7571|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_67	105559.Nwat_2579	0.0004741	53.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS1_k127_3035419_34	1121015.N789_01080	2.101e-20	108.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X30C@135614|Xanthomonadales	1224|Proteobacteria	M	NAD dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS1_k127_3035419_49	404589.Anae109_3917	6.342e-12	80.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_3917|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_41	610130.Closa_2425	4.294e-16	90.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,21XSD@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
GDHHQS1_k127_3035419_54	1190606.AJYG01000085_gene3243	3.099e-07	63.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales	135623|Vibrionales	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS1_k127_3035419_20	518766.Rmar_2366	1.829e-40	168.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS1_k127_3035419_48	880526.KE386488_gene689	3.02e-12	81.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,2FR4X@200643|Bacteroidia,22VDC@171550|Rikenellaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
GDHHQS1_k127_3035419_31	1349822.NSB1T_10155	2.095e-24	119.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
GDHHQS1_k127_3035419_42	1499683.CCFF01000017_gene2080	2.6e-15	91.0	28N78@1|root,2ZBBY@2|Bacteria,1VWWN@1239|Firmicutes,24QA9@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
GDHHQS1_k127_3035419_63	69319.XP_008544740.1	3.915e-05	57.0	28H66@1|root,2QPJ1@2759|Eukaryota,38DN3@33154|Opisthokonta,3BESR@33208|Metazoa,3CURE@33213|Bilateria,41X8N@6656|Arthropoda,3SG2Y@50557|Insecta,46E25@7399|Hymenoptera	33208|Metazoa	S	Tetratricopeptide repeat	TTC14	-	-	ko:K17908	ko04136,ko04138,ko04140,map04136,map04138,map04140	-	-	-	ko00000,ko00001,ko02000,ko03029,ko04131	9.A.15.1	-	-	TPR_11,TPR_2,TPR_8
GDHHQS1_k127_3035419_53	105425.BBPL01000035_gene4152	1.6e-07	65.0	COG0457@1|root,COG0457@2|Bacteria,2HPQU@201174|Actinobacteria,2NK23@228398|Streptacidiphilus	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_33	1321778.HMPREF1982_00647	7.259e-21	108.0	28N78@1|root,2ZBBY@2|Bacteria,1VWWN@1239|Firmicutes,24QA9@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
GDHHQS1_k127_3035419_50	404589.Anae109_3917	2.227e-11	78.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_3917|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_47	404589.Anae109_3917	1.632e-12	83.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_3917|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_66	1336208.JADY01000012_gene2935	0.0003501	54.0	2DWIE@1|root,340GU@2|Bacteria,1NZ7I@1224|Proteobacteria,2USW7@28211|Alphaproteobacteria,2JXG9@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_55	298655.KI912266_gene3286	9.054e-07	63.0	2BK9Q@1|root,32EPW@2|Bacteria,2H0WI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3035419_23	593750.Metfor_1649	7.65e-34	152.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_3035419_21	404589.Anae109_1700	7.27e-39	161.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GDHHQS1_k127_3035419_45	28444.JODQ01000006_gene73	1.43e-14	88.0	COG0641@1|root,COG0641@2|Bacteria,2GMTV@201174|Actinobacteria,4EJC9@85012|Streptosporangiales	201174|Actinobacteria	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_3035419_19	886293.Sinac_5863	7.595e-46	182.0	COG0603@1|root,COG0603@2|Bacteria,2IZ5W@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS1_k127_3035419_44	1121374.KB891585_gene2264	1.126e-14	85.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
GDHHQS1_k127_3035419_58	670487.Ocepr_0541	4.522e-06	60.0	COG1057@1|root,COG1057@2|Bacteria,1WJ70@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS1_k127_3035419_28	56780.SYN_01692	4.105e-27	126.0	COG0204@1|root,COG0204@2|Bacteria,1P3XM@1224|Proteobacteria	1224|Proteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS1_k127_3035419_14	984262.SGRA_1401	5.326e-69	239.0	COG0304@1|root,COG0304@2|Bacteria,4NDXP@976|Bacteroidetes,1IPNE@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS1_k127_3079633_0	608506.COB47_1145	6.957e-317	996.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS1_k127_3079633_1	1009370.ALO_11594	4.073e-137	444.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes	909932|Negativicutes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS1_k127_3079633_3	1267533.KB906734_gene4271	6.044e-93	316.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS1_k127_3079633_2	273068.TTE1761	4.627e-136	444.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS1_k127_3079633_12	1192034.CAP_5779	3.781e-05	51.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS1_k127_3079633_5	1183438.GKIL_3659	5.494e-51	204.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria	1117|Cyanobacteria	E	'ABC-type branched-chain amino acid transport	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
GDHHQS1_k127_3079633_8	1117647.M5M_14495	1.968e-31	142.0	COG3239@1|root,COG3239@2|Bacteria,1NQ1W@1224|Proteobacteria,1RQTG@1236|Gammaproteobacteria,1J789@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG3239 Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GDHHQS1_k127_3079633_7	314278.NB231_14198	5.067e-36	150.0	COG0491@1|root,COG0491@2|Bacteria,1RGCD@1224|Proteobacteria,1S4WB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
GDHHQS1_k127_3079633_10	883096.HMPREF9699_01029	3.096e-13	76.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1I3JR@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS1_k127_3079633_6	290315.Clim_1272	1.526e-44	169.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.2.1.52,3.4.13.22	ko:K01207,ko:K08641	ko00520,ko00531,ko01100,ko01501,ko01502,ko02020,map00520,map00531,map01100,map01501,map01502,map02020	M00628,M00651	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GDHHQS1_k127_3079633_9	1123366.TH3_03344	1.48e-19	100.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,2UE4Y@28211|Alphaproteobacteria,2JTCI@204441|Rhodospirillales	204441|Rhodospirillales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3079633_4	935866.JAER01000012_gene3484	5.223e-89	316.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4DPH0@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	putA_2	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
GDHHQS1_k127_310272_0	768670.Calni_0857	2.176e-64	243.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DEAD,DUF4384,Helicase_C,Peptidase_C14,Polysacc_deac_1,TPR_11,TPR_16,TPR_2,TPR_8,WD40
GDHHQS1_k127_3104778_10	497964.CfE428DRAFT_3024	6.678e-55	194.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GDHHQS1_k127_3104778_25	443143.GM18_0491	5.715e-15	86.0	COG0095@1|root,COG0095@2|Bacteria,1RI3T@1224|Proteobacteria,42SQP@68525|delta/epsilon subdivisions,2WQH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS1_k127_3104778_35	235985.BBPN01000054_gene7731	0.0008097	47.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,2NJGQ@228398|Streptacidiphilus	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS1_k127_3104778_28	1169154.KB897779_gene2874	3.367e-09	69.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria	201174|Actinobacteria	NT	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
GDHHQS1_k127_3104778_33	1121861.KB899920_gene2880	0.0004116	54.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,2JR6C@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_3104778_7	1121439.dsat_2168	1.43e-58	217.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2X5HP@28221|Deltaproteobacteria,2MG6D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
GDHHQS1_k127_3104778_26	1357279.N018_20160	1.751e-14	82.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Z7FK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	Sensory box protein response regulator	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_3104778_20	1499499.EV06_0610	1.116e-20	96.0	COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1MKWM@1212|Prochloraceae	1117|Cyanobacteria	K	response regulator	ycf29	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_3104778_23	365528.KB891230_gene1824	1.356e-16	89.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_3104778_27	349741.Amuc_1570	1.417e-11	74.0	2EKXK@1|root,33EM4@2|Bacteria,46WCN@74201|Verrucomicrobia,2IUG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3104778_24	44689.DDB0186655	2.772e-16	93.0	COG0170@1|root,KOG4453@2759|Eukaryota,3XDDN@554915|Amoebozoa	554915|Amoebozoa	I	phytol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3104778_11	1121434.AULY01000007_gene1436	8.283e-55	213.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,2M8W5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_3104778_31	543728.Vapar_3097	3.12e-07	64.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,4AA7C@80864|Comamonadaceae	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
GDHHQS1_k127_3104778_16	871963.Desdi_2763	1.138e-36	149.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS1_k127_3104778_21	66373.JOFQ01000002_gene5204	7.316e-19	101.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_3104778_1	1123368.AUIS01000007_gene2752	1.141e-121	425.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,2NCHK@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS1_k127_3104778_3	1232410.KI421421_gene3677	1.022e-95	328.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,43S79@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,Methyltransf_25
GDHHQS1_k127_3104778_6	304371.MCP_2273	1.282e-60	225.0	arCOG00787@1|root,arCOG00787@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS1_k127_3104778_29	7897.ENSLACP00000018270	3.737e-09	66.0	COG0666@1|root,KOG0504@2759|Eukaryota,3A0WN@33154|Opisthokonta,3BPHY@33208|Metazoa,3CY26@33213|Bilateria,482UZ@7711|Chordata,491NZ@7742|Vertebrata	33208|Metazoa	S	ankyrin repeat, SAM and basic leucine zipper	ASZ1	GO:0000003,GO:0000280,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007140,GO:0007276,GO:0007281,GO:0007283,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016070,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034587,GO:0034641,GO:0034660,GO:0035770,GO:0036464,GO:0043046,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044728,GO:0045495,GO:0046483,GO:0048232,GO:0048285,GO:0048468,GO:0048609,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0060293,GO:0071546,GO:0071704,GO:0071840,GO:0090304,GO:0140013,GO:1901360,GO:1903046,GO:1990904	-	ko:K18410	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_3,Ank_4,SAM_1,SAM_2
GDHHQS1_k127_3104778_9	1121423.JONT01000015_gene1332	1.207e-57	225.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	CHB_HEX_C_1,Inhibitor_I9,Peptidase_S8
GDHHQS1_k127_3104778_5	1408422.JHYF01000001_gene2797	3.813e-62	231.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,36FEY@31979|Clostridiaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GDHHQS1_k127_3104778_13	990285.RGCCGE502_04795	3.439e-46	188.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,2U7IG@28211|Alphaproteobacteria,4BCZX@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS1_k127_3104778_32	631454.N177_4099	2.172e-05	53.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,DUF4437
GDHHQS1_k127_3104778_19	391625.PPSIR1_41179	2.871e-22	105.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS1_k127_3104778_34	1144275.COCOR_07846	0.0005588	52.0	COG3000@1|root,COG3000@2|Bacteria,1RC8C@1224|Proteobacteria,435BX@68525|delta/epsilon subdivisions,2WZPE@28221|Deltaproteobacteria,2Z2GQ@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS1_k127_3104778_22	266117.Rxyl_0137	3.344e-18	99.0	COG0449@1|root,COG0449@2|Bacteria,2IIQ7@201174|Actinobacteria,4CQF9@84995|Rubrobacteria	84995|Rubrobacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	-
GDHHQS1_k127_3104778_17	909663.KI867150_gene1451	3.129e-30	132.0	COG0500@1|root,COG2226@2|Bacteria,1PEBD@1224|Proteobacteria,42T7H@68525|delta/epsilon subdivisions,2WPN7@28221|Deltaproteobacteria,2MQP2@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS1_k127_3104778_12	397945.Aave_1841	1.389e-49	194.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VKNA@28216|Betaproteobacteria,4AC7A@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	aidB_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
GDHHQS1_k127_3104778_4	1123499.KB908019_gene2266	5.135e-67	236.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KQ20@206351|Neisseriales	206351|Neisseriales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS1_k127_3104778_8	243231.GSU0031	9.527e-58	214.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
GDHHQS1_k127_3104778_18	1007096.BAGW01000014_gene1168	1.122e-22	113.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,2N6B1@216572|Oscillospiraceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS1_k127_3104778_0	386456.JQKN01000012_gene1035	3.768e-237	748.0	COG0443@1|root,arCOG03060@2157|Archaea,2XT86@28890|Euryarchaeota,23NSE@183925|Methanobacteria	183925|Methanobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS1_k127_3104778_2	237727.NAP1_05365	1.801e-106	357.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS1_k127_3104778_14	720554.Clocl_2765	3.71e-41	161.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GDHHQS1_k127_3104778_15	1121430.JMLG01000001_gene2275	4.637e-38	145.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,262CU@186807|Peptococcaceae	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS1_k127_3104778_30	1041504.RATSFB_0785	4.025e-09	60.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,36MKD@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS1_k127_3140712_1	706587.Desti_3772	2.676e-34	138.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MRPT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
GDHHQS1_k127_3140712_2	1125699.HMPREF9194_01471	2.251e-05	52.0	COG1585@1|root,COG1585@2|Bacteria,2J8AF@203691|Spirochaetes	203691|Spirochaetes	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
GDHHQS1_k127_3140712_0	771875.Ferpe_0943	1.321e-71	261.0	COG0330@1|root,COG0330@2|Bacteria,2GC8F@200918|Thermotogae	200918|Thermotogae	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_3233622_1	984262.SGRA_1117	1.8e-23	115.0	COG2242@1|root,COG2242@2|Bacteria,4NYI3@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS1_k127_3233622_0	1178482.BJB45_09570	6e-24	108.0	COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,1SCAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator, (TetR family	VVA0998	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
GDHHQS1_k127_3233622_2	886293.Sinac_4588	3.059e-17	83.0	COG0265@1|root,COG0265@2|Bacteria,2IYN3@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_3260269_32	1353529.M899_1881	0.0001614	44.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2MSUP@213481|Bdellovibrionales,2X5RQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS1_k127_3260269_9	266117.Rxyl_2626	1.98e-101	343.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS1_k127_3260269_22	118161.KB235919_gene6184	3.005e-31	140.0	COG1215@1|root,COG1215@2|Bacteria,1G46A@1117|Cyanobacteria,3VIYH@52604|Pleurocapsales	1117|Cyanobacteria	M	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_3260269_21	1210884.HG799463_gene9897	6.511e-37	156.0	COG0500@1|root,COG2226@2|Bacteria,2J51A@203682|Planctomycetes	203682|Planctomycetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_3260269_5	395961.Cyan7425_1965	2.288e-143	468.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
GDHHQS1_k127_3260269_11	1121335.Clst_0008	3.264e-87	296.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_3260269_17	555079.Toce_2275	5.863e-63	227.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS1_k127_3260269_16	867903.ThesuDRAFT_00219	1.238e-67	243.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WD07@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS1_k127_3260269_10	1353529.M899_2052	1.401e-97	337.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,42QQ1@68525|delta/epsilon subdivisions,2MSYG@213481|Bdellovibrionales,2WMNS@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
GDHHQS1_k127_3260269_14	1121878.AUGL01000010_gene951	5.12e-71	250.0	KOG0788@1|root,2Z9Q6@2|Bacteria,1R6QG@1224|Proteobacteria,1RYA8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM S-adenosylmethionine decarboxylase	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	SAM_decarbox
GDHHQS1_k127_3260269_23	32051.SynWH7803_2449	1.091e-28	121.0	COG1694@1|root,COG3956@2|Bacteria,1G151@1117|Cyanobacteria,1GYYW@1129|Synechococcus	1117|Cyanobacteria	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG
GDHHQS1_k127_3260269_7	643648.Slip_0011	3.56e-122	405.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42JR4@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS1_k127_3260269_1	1121428.DESHY_30001___1	4.585e-289	910.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS1_k127_3260269_2	338963.Pcar_0004	1.32e-240	770.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS1_k127_3260269_15	1121289.JHVL01000043_gene1081	5.13e-68	244.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,36E0C@31979|Clostridiaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GDHHQS1_k127_3260269_6	1267580.AF6_0001	7.347e-125	413.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,21V4X@150247|Anoxybacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS1_k127_3260269_24	717231.Flexsi_0985	1.475e-26	115.0	COG1544@1|root,COG1544@2|Bacteria,2GFDP@200930|Deferribacteres	200930|Deferribacteres	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
GDHHQS1_k127_3260269_12	358681.BBR47_52740	2.449e-82	286.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,26QHT@186822|Paenibacillaceae	91061|Bacilli	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
GDHHQS1_k127_3260269_13	1121430.JMLG01000009_gene430	7.243e-73	268.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,2616Z@186807|Peptococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
GDHHQS1_k127_3260269_28	933262.AXAM01000066_gene1679	5.245e-18	97.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MK4F@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
GDHHQS1_k127_3260269_25	610130.Closa_0203	1.073e-25	119.0	COG3444@1|root,COG3444@2|Bacteria,1UXMU@1239|Firmicutes,25MHI@186801|Clostridia,2239Z@1506553|Lachnoclostridium	186801|Clostridia	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
GDHHQS1_k127_3260269_29	378806.STAUR_7339	9.354e-17	93.0	COG3716@1|root,COG3716@2|Bacteria,1MWTZ@1224|Proteobacteria,42SXR@68525|delta/epsilon subdivisions,2WPQN@28221|Deltaproteobacteria,2YYU5@29|Myxococcales	28221|Deltaproteobacteria	M	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
GDHHQS1_k127_3260269_27	497964.CfE428DRAFT_4274	6.951e-21	104.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS1_k127_3260269_4	1031288.AXAA01000009_gene666	8.593e-148	492.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS1_k127_3260269_3	644966.Tmar_2189	3.332e-209	694.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WCEY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS1_k127_3260269_20	1232410.KI421413_gene591	1.328e-49	189.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,43SF5@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS1_k127_3260269_26	582899.Hden_2857	5.915e-25	119.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3260269_8	1304883.KI912532_gene1230	1.177e-119	412.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2VIN9@28216|Betaproteobacteria,2KUVW@206389|Rhodocyclales	206389|Rhodocyclales	M	UDP-glucose 4-epimerase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_3260269_19	1191523.MROS_1829	3.581e-50	203.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS1_k127_3260269_18	130081.XP_005706629.1	4.789e-52	209.0	COG0439@1|root,2RN4Y@2759|Eukaryota	2759|Eukaryota	I	ATP-grasp domain	-	-	6.3.2.11	ko:K14755	ko00330,ko00340,ko00410,map00330,map00340,map00410	-	R00910,R00912,R01164,R01991,R03286	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_4
GDHHQS1_k127_3260269_30	67257.JODR01000037_gene1555	3.263e-16	85.0	COG1959@1|root,COG1959@2|Bacteria,2IFQN@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS1_k127_3260269_0	1210884.HG799463_gene9843	0.0	1019.0	COG3256@1|root,COG3256@2|Bacteria,2J2IF@203682|Planctomycetes	203682|Planctomycetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
GDHHQS1_k127_3260269_31	697282.Mettu_1039	2.046e-13	82.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1XDMJ@135618|Methylococcales	135618|Methylococcales	E	PFAM Aminotransferase, class I	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_328059_0	443143.GM18_3886	6.886e-128	448.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_328059_10	102125.Xen7305DRAFT_00028860	6.992e-11	76.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1G2HS@1117|Cyanobacteria,3VKW9@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_328059_5	760568.Desku_0372	1.869e-45	177.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS1_k127_328059_2	1267535.KB906767_gene1306	9.627e-74	270.0	COG1194@1|root,COG1194@2|Bacteria,3Y50Y@57723|Acidobacteria,2JHYP@204432|Acidobacteriia	204432|Acidobacteriia	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS1_k127_328059_8	1121940.AUDZ01000006_gene199	2.228e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1RA6Z@1224|Proteobacteria,1SYDG@1236|Gammaproteobacteria,1XP8J@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ygiX	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_328059_9	1380394.JADL01000009_gene3147	2.865e-20	104.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS1_k127_328059_1	1242864.D187_000433	8.869e-94	322.0	COG2234@1|root,COG2234@2|Bacteria,1MXJC@1224|Proteobacteria,42RKA@68525|delta/epsilon subdivisions,2WUCM@28221|Deltaproteobacteria,2YWU8@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
GDHHQS1_k127_328059_7	502025.Hoch_3692	1.727e-26	119.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
GDHHQS1_k127_328059_4	517418.Ctha_0519	8.665e-50	185.0	COG0637@1|root,COG0637@2|Bacteria,1FE29@1090|Chlorobi	1090|Chlorobi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS1_k127_328059_6	697282.Mettu_4249	6.253e-33	129.0	2DVNB@1|root,32UZS@2|Bacteria,1N65J@1224|Proteobacteria,1SF9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_328059_3	330214.NIDE3111	1.004e-61	222.0	COG0179@1|root,COG0179@2|Bacteria,3J1AP@40117|Nitrospirae	40117|Nitrospirae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS1_k127_3325098_6	1122222.AXWR01000019_gene2708	7.957e-32	128.0	COG0346@1|root,COG0346@2|Bacteria,1WJZW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GDHHQS1_k127_3325098_4	688270.Celal_1251	1.906e-51	202.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,1F838@104264|Cellulophaga	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS1_k127_3325098_2	529709.PYCH_16980	8.693e-73	256.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS1_k127_3325098_5	370438.PTH_1362	3.46e-49	193.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS1_k127_3325098_3	289376.THEYE_A2006	1.877e-53	208.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3J18S@40117|Nitrospirae	40117|Nitrospirae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3325098_1	760142.Hipma_0476	3.308e-122	416.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
GDHHQS1_k127_3325098_0	381764.Fnod_1752	5.883e-187	598.0	COG1884@1|root,COG1884@2|Bacteria,2GBZM@200918|Thermotogae	200918|Thermotogae	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS1_k127_3325098_7	443143.GM18_2430	5.51e-23	102.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,42VKG@68525|delta/epsilon subdivisions,2WSD0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS1_k127_3325098_8	1191523.MROS_1276	4.955e-05	49.0	COG2304@1|root,COG2911@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	ydbH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DctA-YdbH,TamB,VWA
GDHHQS1_k127_33283_5	313628.LNTAR_10466	8.604e-28	116.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS1_k127_33283_3	935948.KE386495_gene1761	1.399e-63	227.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,42GV6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS1_k127_33283_4	349161.Dred_1757	4.529e-39	163.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,261XM@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_33283_7	1041930.Mtc_0196	1.871e-17	97.0	arCOG03980@1|root,arCOG03980@2157|Archaea,2Y3V0@28890|Euryarchaeota,2NAVB@224756|Methanomicrobia	224756|Methanomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_33283_8	1120973.AQXL01000117_gene380	8.201e-14	81.0	28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,27A60@186823|Alicyclobacillaceae	91061|Bacilli	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
GDHHQS1_k127_33283_0	204669.Acid345_0668	2.445e-139	455.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GDHHQS1_k127_33283_6	1121403.AUCV01000021_gene3590	2.71e-25	111.0	2E7BS@1|root,331V2@2|Bacteria,1N7TQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_33283_2	1210884.HG799462_gene8369	7.473e-81	276.0	COG2057@1|root,COG2057@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_33283_1	224325.AF_1199	2.459e-83	291.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_33283_9	1348114.OM33_21185	1.266e-05	56.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,2Q36Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
GDHHQS1_k127_3332781_0	1121946.AUAX01000004_gene595	4.464e-126	445.0	COG0366@1|root,COG0366@2|Bacteria,2GQHX@201174|Actinobacteria,4DJ4F@85008|Micromonosporales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
GDHHQS1_k127_3332781_1	1254432.SCE1572_11300	7.182e-71	251.0	2E55N@1|root,32ZYI@2|Bacteria,1NFET@1224|Proteobacteria,437UG@68525|delta/epsilon subdivisions,2X342@28221|Deltaproteobacteria,2YU52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3544374_2	1161401.ASJA01000026_gene20	0.0002145	49.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,43XQS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	U	Pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS1_k127_3544374_0	1173025.GEI7407_3352	8.276e-141	477.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1H9DA@1150|Oscillatoriales	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS1_k127_3544374_1	1440774.Y900_015575	1.373e-13	74.0	COG0477@1|root,COG2814@2|Bacteria,2HSJI@201174|Actinobacteria,23CNI@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_3570146_10	1408418.JNJH01000020_gene967	0.0001075	47.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2JV8U@204441|Rhodospirillales	204441|Rhodospirillales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS1_k127_3570146_8	290340.AAur_2697	5.189e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,1W88X@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_3570146_0	401526.TcarDRAFT_1563	1.854e-151	497.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_3570146_3	373903.Hore_05990	3.562e-67	259.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WAFC@53433|Halanaerobiales	186801|Clostridia	U	PFAM Bacterial type II secretion system protein F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS1_k127_3570146_9	1166948.JPZL01000002_gene1116	7.749e-13	83.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XH3V@135619|Oceanospirillales	135619|Oceanospirillales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_3570146_4	243231.GSU2028	1.006e-43	177.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS1_k127_3570146_7	234267.Acid_6770	6.125e-19	101.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,3Y77J@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16
GDHHQS1_k127_3570146_5	886293.Sinac_1397	3.25e-38	166.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3570146_2	1396141.BATP01000003_gene5111	7.612e-72	257.0	COG0745@1|root,COG1235@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,COG2203@2|Bacteria,46UKB@74201|Verrucomicrobia,2IVU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Response_reg
GDHHQS1_k127_3570146_6	522306.CAP2UW1_3137	7.42e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_3570146_1	1254432.SCE1572_52300	1.215e-108	371.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WNH1@28221|Deltaproteobacteria,2Z329@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS1_k127_3570146_11	685778.AORL01000004_gene3481	0.000592	52.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
GDHHQS1_k127_3711932_1	1173024.KI912153_gene217	5.177e-132	450.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS1_k127_3711932_0	1173024.KI912153_gene216	0.0	1567.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
GDHHQS1_k127_3711932_4	56780.SYN_01695	1.926e-18	94.0	COG0764@1|root,COG0764@2|Bacteria,1N0HJ@1224|Proteobacteria,42ZU6@68525|delta/epsilon subdivisions,2WV96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS1_k127_3711932_2	227377.CBU_0037	2.013e-28	130.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
GDHHQS1_k127_3711932_3	56780.SYN_01697	5.687e-25	119.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria	1224|Proteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
GDHHQS1_k127_3711932_5	1121920.AUAU01000020_gene2550	4.626e-05	46.0	COG0433@1|root,COG0433@2|Bacteria,3Y69X@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF853
GDHHQS1_k127_3731229_1	1278073.MYSTI_04894	5.412e-178	568.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
GDHHQS1_k127_3731229_40	616991.JPOO01000003_gene109	6.261e-12	78.0	2CK2Q@1|root,303GN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3731229_45	1408473.JHXO01000013_gene586	3.499e-07	57.0	COG4244@1|root,COG4244@2|Bacteria,4NPYK@976|Bacteroidetes,2FYNE@200643|Bacteroidia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
GDHHQS1_k127_3731229_8	1121438.JNJA01000018_gene3297	5.046e-74	284.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2M8HM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,PAS_8
GDHHQS1_k127_3731229_5	706587.Desti_2024	1.603e-101	356.0	COG0784@1|root,COG0834@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria,2MQW1@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_3731229_4	880073.Calab_1764	3.28e-130	446.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_3731229_43	1321786.HMPREF1992_02122	5.773e-08	61.0	COG3018@1|root,COG3018@2|Bacteria,1V907@1239|Firmicutes,4H4Y8@909932|Negativicutes	909932|Negativicutes	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
GDHHQS1_k127_3731229_22	1216932.CM240_1942	1.827e-43	170.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_3731229_44	933262.AXAM01000032_gene695	2.447e-07	62.0	COG1462@1|root,COG1462@2|Bacteria,1PUD4@1224|Proteobacteria,43530@68525|delta/epsilon subdivisions,2X94S@28221|Deltaproteobacteria,2MP2K@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_3731229_13	219305.MCAG_04899	3.474e-61	223.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS1_k127_3731229_30	1278073.MYSTI_06364	5.873e-26	125.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AKM@68525|delta/epsilon subdivisions,2X60K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS1_k127_3731229_16	1286171.EAL2_808p03370	7.813e-58	221.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,25ZF5@186806|Eubacteriaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GDHHQS1_k127_3731229_47	1504822.CCNO01000014_gene1643	2.001e-05	59.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
GDHHQS1_k127_3731229_27	224324.aq_2043	1.059e-34	143.0	COG0755@1|root,COG0755@2|Bacteria,2G433@200783|Aquificae	200783|Aquificae	O	cytochrome c-type biogenesis protein CcsB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS1_k127_3731229_10	867903.ThesuDRAFT_01613	7.332e-69	257.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS1_k127_3731229_29	1237149.C900_05483	7.021e-33	147.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
GDHHQS1_k127_3731229_25	671143.DAMO_1672	1.135e-36	146.0	COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS1_k127_3731229_6	1437425.CSEC_1623	2.084e-95	332.0	COG1290@1|root,COG1290@2|Bacteria,2JFNC@204428|Chlamydiae	204428|Chlamydiae	C	Cytochrome b/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
GDHHQS1_k127_3731229_28	247490.KSU1_B0693	3.849e-34	147.0	COG2010@1|root,COG2010@2|Bacteria,2IYC2@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS1_k127_3731229_42	1379698.RBG1_1C00001G0853	5.789e-11	70.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3731229_24	1121468.AUBR01000029_gene1575	1.248e-38	159.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,42GI1@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Monogalactosyldiacylglycerol synthase	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
GDHHQS1_k127_3731229_19	330214.NIDE1596	1.003e-50	188.0	COG1225@1|root,COG1225@2|Bacteria,3J13P@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS1_k127_3731229_39	886293.Sinac_5067	2.67e-12	72.0	COG1145@1|root,COG1145@2|Bacteria,2IZZ5@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S binding domain	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	Fer4
GDHHQS1_k127_3731229_12	96561.Dole_2898	3.365e-67	246.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_3731229_9	1163407.UU7_04737	4.677e-69	242.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GDHHQS1_k127_3731229_31	296591.Bpro_0624	1.429e-24	109.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS1_k127_3731229_26	518766.Rmar_0611	1.571e-35	151.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS1_k127_3731229_11	1192034.CAP_2100	2.267e-68	253.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,42T8N@68525|delta/epsilon subdivisions,2WZ91@28221|Deltaproteobacteria,2Z1M2@29|Myxococcales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS1_k127_3731229_20	1123248.KB893321_gene524	1.036e-49	184.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,1ISM9@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS1_k127_3731229_32	1117315.AHCA01000001_gene2433	3.807e-21	99.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,2Q4FN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
GDHHQS1_k127_3731229_3	330214.NIDE4188	1.587e-131	442.0	28J7E@1|root,2Z92U@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
GDHHQS1_k127_3731229_14	316067.Geob_3261	1.373e-58	222.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,43AJV@68525|delta/epsilon subdivisions,2X601@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS1_k127_3731229_34	867845.KI911784_gene2774	1.807e-19	100.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GDHHQS1_k127_3731229_21	234267.Acid_2359	1.146e-46	181.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria	2|Bacteria	S	Radical SAM domain protein	-	-	-	ko:K15045	ko05164,map05164	-	-	-	ko00000,ko00001	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_3731229_38	575615.HMPREF0670_01496	4.377e-13	74.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS1_k127_3731229_0	1267535.KB906767_gene4458	1.581e-179	592.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS1_k127_3731229_41	1192034.CAP_2675	1.155e-11	76.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,43BWP@68525|delta/epsilon subdivisions,2X77H@28221|Deltaproteobacteria,2YXA7@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
GDHHQS1_k127_3731229_37	1131269.AQVV01000039_gene1548	1.698e-13	79.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
GDHHQS1_k127_3731229_17	886293.Sinac_6888	2.294e-56	211.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS1_k127_3731229_46	641491.DND132_3043	7.568e-06	55.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WRD9@28221|Deltaproteobacteria,2MD2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	oxidase, subunit IV	coxD	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GDHHQS1_k127_3731229_23	478741.JAFS01000002_gene335	7.742e-40	158.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS1_k127_3731229_2	382464.ABSI01000010_gene3668	1.037e-163	534.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
GDHHQS1_k127_3731229_18	1156937.MFUM_700064	9.656e-54	199.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,37G6Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GDHHQS1_k127_3731229_15	1167006.UWK_00992	3.506e-58	213.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,430CM@68525|delta/epsilon subdivisions,2WVWF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
GDHHQS1_k127_3731229_33	404589.Anae109_3720	5.537e-20	100.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,430CM@68525|delta/epsilon subdivisions,2WVWF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
GDHHQS1_k127_3731229_36	886293.Sinac_5787	1.927e-14	82.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,PA14
GDHHQS1_k127_3731229_7	1210884.HG799474_gene15174	1.688e-90	304.0	COG0730@1|root,COG0730@2|Bacteria,2J37C@203682|Planctomycetes	203682|Planctomycetes	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
GDHHQS1_k127_3731229_35	190486.XAC2194	2.605e-17	86.0	2CK96@1|root,33BNP@2|Bacteria,1P6ZI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3755317_0	313628.LNTAR_24723	2.758e-103	346.0	COG0820@1|root,COG0820@2|Bacteria	2|Bacteria	J	rRNA (adenine-C2-)-methyltransferase activity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
GDHHQS1_k127_3755317_1	1444712.BN1013_00604	1.427e-37	148.0	COG0824@1|root,COG0824@2|Bacteria,2JH3F@204428|Chlamydiae	204428|Chlamydiae	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GDHHQS1_k127_376876_5	321327.CYA_2137	1.17e-30	139.0	COG5285@1|root,COG5285@2|Bacteria,1G486@1117|Cyanobacteria,1H2S3@1129|Synechococcus	1117|Cyanobacteria	C	Phytanoyl-CoA dioxygenase PhyH family protein	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
GDHHQS1_k127_376876_7	522306.CAP2UW1_3213	2.547e-22	111.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2VVR6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS1_k127_376876_0	1380394.JADL01000014_gene240	9.207e-165	549.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2JRNW@204441|Rhodospirillales	204441|Rhodospirillales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_376876_1	1131269.AQVV01000002_gene1205	1.632e-91	323.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
GDHHQS1_k127_376876_3	554065.XP_005843969.1	2.583e-66	232.0	COG0221@1|root,KOG1626@2759|Eukaryota,37R74@33090|Viridiplantae,34J91@3041|Chlorophyta	3041|Chlorophyta	C	soluble inorganic pyrophosphatase	-	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
GDHHQS1_k127_376876_4	314345.SPV1_01317	1.484e-34	143.0	COG0739@1|root,COG0739@2|Bacteria,1QVU7@1224|Proteobacteria	1224|Proteobacteria	M	Membrane proteins related to metalloendopeptidases	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
GDHHQS1_k127_376876_2	96561.Dole_2900	1.36e-66	244.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
GDHHQS1_k127_376876_6	937777.Deipe_1494	1.953e-24	108.0	COG0745@1|root,COG0745@2|Bacteria	937777.Deipe_1494|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3814192_12	562970.Btus_1957	9.275e-24	103.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS1_k127_3814192_9	861299.J421_4334	1.265e-40	159.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS1_k127_3814192_6	391623.TERMP_01733	7.774e-64	228.0	COG0388@1|root,arCOG00062@2157|Archaea,2XVVK@28890|Euryarchaeota,242PM@183968|Thermococci	183968|Thermococci	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS1_k127_3814192_10	485913.Krac_10271	1.299e-33	140.0	COG0500@1|root,COG2226@2|Bacteria,2GA94@200795|Chloroflexi	200795|Chloroflexi	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS1_k127_3814192_4	935863.AWZR01000005_gene2180	6.225e-92	323.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1X5E6@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_3814192_7	1121272.KB903291_gene3632	2.62e-59	226.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4DBWR@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_3814192_5	1536772.R70723_29905	4.689e-80	276.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,26RTV@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase family 2	arnC	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GDHHQS1_k127_3814192_3	450851.PHZ_c0010	3.119e-93	326.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2KF7K@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_3814192_8	1001585.MDS_1835	2.926e-46	185.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1SYE3@1236|Gammaproteobacteria,1YH6H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS1_k127_3814192_2	1131266.ARWQ01000013_gene65	9.74e-128	416.0	COG0451@1|root,arCOG01369@2157|Archaea	2157|Archaea	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS1_k127_3814192_13	1224746.B932_2181	1.406e-12	80.0	COG0500@1|root,COG2226@2|Bacteria,1QWJE@1224|Proteobacteria,2U37M@28211|Alphaproteobacteria,2JZF5@204441|Rhodospirillales	204441|Rhodospirillales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_3814192_1	1254432.SCE1572_23185	6.375e-161	532.0	2BRHU@1|root,32KGU@2|Bacteria,1Q2UP@1224|Proteobacteria,438H4@68525|delta/epsilon subdivisions,2X3RX@28221|Deltaproteobacteria,2YWYJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3814192_11	1121380.JNIW01000122_gene310	1.91e-25	115.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3814192_0	903818.KI912268_gene2018	2.127e-219	689.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS1_k127_3819345_1	234267.Acid_5757	3.467e-29	128.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3819345_0	314230.DSM3645_29956	2.872e-48	184.0	COG0515@1|root,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
GDHHQS1_k127_3831828_3	1123377.AUIV01000007_gene1263	1.372e-119	398.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1X37F@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
GDHHQS1_k127_3831828_18	589865.DaAHT2_1350	0.0009511	52.0	COG0457@1|root,COG0457@2|Bacteria,1R900@1224|Proteobacteria,42PXF@68525|delta/epsilon subdivisions,2WKEF@28221|Deltaproteobacteria,2MPEK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
GDHHQS1_k127_3831828_15	1380390.JIAT01000010_gene3953	1.132e-08	68.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_3831828_13	1125971.ASJB01000064_gene6419	5.566e-20	104.0	COG3409@1|root,COG3409@2|Bacteria,2GMGY@201174|Actinobacteria,4E1ZI@85010|Pseudonocardiales	201174|Actinobacteria	M	Fungal chitosanase of glycosyl hydrolase group 75	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_75
GDHHQS1_k127_3831828_1	330214.NIDE4018	9.273e-177	574.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS1_k127_3831828_11	568076.XP_007825855.1	5.716e-27	126.0	COG0666@1|root,KOG4177@2759|Eukaryota,39VF6@33154|Opisthokonta,3NZ3K@4751|Fungi,3QNR2@4890|Ascomycota,216DG@147550|Sordariomycetes,3TEZY@5125|Hypocreales,3G5YG@34397|Clavicipitaceae	4751|Fungi	M	Heterokaryon incompatibility protein (HET)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,HET
GDHHQS1_k127_3831828_17	1267535.KB906767_gene2264	0.0001517	53.0	29E6W@1|root,3014W@2|Bacteria,3Y4JR@57723|Acidobacteria,2JJ83@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3831828_0	429009.Adeg_1440	7.712e-193	631.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42EUK@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS1_k127_3831828_8	83406.HDN1F_08820	2.632e-55	202.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria	1224|Proteobacteria	Q	Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS1_k127_3831828_2	402881.Plav_3274	1.305e-119	400.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	flavoproteins	yhiN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GDHHQS1_k127_3831828_9	1279038.KB907340_gene1450	1.035e-52	190.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2UACH@28211|Alphaproteobacteria,2JS80@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
GDHHQS1_k127_3831828_10	1278073.MYSTI_05912	3.77e-40	162.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS1_k127_3831828_14	1235793.C809_02391	1.29e-14	87.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,27NRD@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS1_k127_3831828_16	754476.Q7A_2209	2.432e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS1_k127_3831828_4	243231.GSU1113	5.151e-90	319.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
GDHHQS1_k127_3831828_6	1196029.ALIM01000014_gene3772	1.652e-78	284.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_3831828_7	1379270.AUXF01000004_gene3069	2.726e-66	246.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
GDHHQS1_k127_3831828_12	218491.ECA0169	4.335e-22	105.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1MRNU@122277|Pectobacterium	1236|Gammaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
GDHHQS1_k127_3831828_5	379066.GAU_2547	2.621e-82	293.0	COG3266@1|root,COG3266@2|Bacteria,1ZT0N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_387429_6	479434.Sthe_2631	1.913e-71	250.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	189775|Thermomicrobia	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS1_k127_387429_2	986075.CathTA2_2562	4.874e-97	340.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_387429_18	443255.SCLAV_1486	0.0005267	53.0	COG3629@1|root,COG3629@2|Bacteria,2I3CQ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GDHHQS1_k127_387429_0	997346.HMPREF9374_0644	8.309e-137	446.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,27B3G@186824|Thermoactinomycetaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_387429_17	748449.Halha_2360	0.0004518	52.0	2DP2M@1|root,3309H@2|Bacteria,1V5H4@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_387429_15	1216007.AOPM01000024_gene2983	2.97e-07	59.0	COG3018@1|root,COG3018@2|Bacteria,1RIA2@1224|Proteobacteria,1S4BX@1236|Gammaproteobacteria,2Q2F9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	N	protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
GDHHQS1_k127_387429_13	880073.Calab_3761	1.09e-09	69.0	COG1462@1|root,COG1462@2|Bacteria,2NQ4P@2323|unclassified Bacteria	2|Bacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,FlgT_C,PG_binding_1
GDHHQS1_k127_387429_9	1216932.CM240_1942	6.341e-31	131.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_387429_7	794903.OPIT5_19775	3.78e-44	179.0	COG1510@1|root,COG1510@2|Bacteria,46VGF@74201|Verrucomicrobia,3K99X@414999|Opitutae	414999|Opitutae	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_387429_8	1196031.ALEG01000019_gene2881	1.323e-31	136.0	COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	hepT	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.30,2.5.1.83	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	-	R09245,R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS1_k127_387429_1	1089552.KI911559_gene2519	1.368e-124	411.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JRCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_387429_4	1089552.KI911559_gene2518	2.107e-94	323.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS1_k127_387429_5	1089552.KI911559_gene2517	1.342e-88	312.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JRCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_387429_3	1089552.KI911559_gene2515	3.491e-95	322.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_387429_14	653386.HMPREF0975_01125	8.568e-09	62.0	COG1396@1|root,COG1396@2|Bacteria,2GR6P@201174|Actinobacteria,4D6CD@85005|Actinomycetales	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS1_k127_387429_11	1396141.BATP01000022_gene353	7.575e-15	84.0	COG2326@1|root,COG2326@2|Bacteria,46UPR@74201|Verrucomicrobia,2IUNN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GDHHQS1_k127_3902692_0	525318.HMPREF0497_2595	9.001e-65	231.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_3942849_0	1160137.KB907308_gene6991	2.661e-74	259.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria,4G4IQ@85025|Nocardiaceae	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
GDHHQS1_k127_3942849_2	1198452.Jab_1c21630	1.755e-10	71.0	COG4977@1|root,COG4977@2|Bacteria,1MXZQ@1224|Proteobacteria,2VS7H@28216|Betaproteobacteria,4795A@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
GDHHQS1_k127_3942849_1	1123376.AUIU01000003_gene1639	1.017e-27	117.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
GDHHQS1_k127_3986497_8	1121028.ARQE01000010_gene954	7.597e-16	87.0	COG1564@1|root,COG1564@2|Bacteria,1REBP@1224|Proteobacteria,2VGVC@28211|Alphaproteobacteria,2PJXQ@255475|Aurantimonadaceae	28211|Alphaproteobacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
GDHHQS1_k127_3986497_2	483219.LILAB_26945	1.854e-75	276.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
GDHHQS1_k127_3986497_1	357804.Ping_1307	3.188e-103	347.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,1S1VG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,HTH_17,SHOCT
GDHHQS1_k127_3986497_0	1297742.A176_06867	6.362e-130	430.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria,2YTVI@29|Myxococcales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	glp	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
GDHHQS1_k127_3986497_7	525903.Taci_0155	3.126e-18	96.0	COG1409@1|root,COG1409@2|Bacteria,3TBDZ@508458|Synergistetes	508458|Synergistetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS1_k127_3986497_9	545695.TREAZ_2863	1.651e-12	81.0	COG1196@1|root,COG1196@2|Bacteria,2J663@203691|Spirochaetes	203691|Spirochaetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3986497_6	1009370.ALO_07313	8.835e-33	133.0	COG3216@1|root,COG3216@2|Bacteria	2|Bacteria	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
GDHHQS1_k127_3986497_5	134676.ACPL_5550	1.65e-33	137.0	COG1974@1|root,COG1974@2|Bacteria,2I9XR@201174|Actinobacteria,4DIWD@85008|Micromonosporales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS1_k127_3986497_11	1283284.AZUK01000001_gene829	1.777e-07	56.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria	1224|Proteobacteria	S	Fe-S protein	RSC1457	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	Cys_rich_CWC,DUF1289
GDHHQS1_k127_3986497_12	300852.55771450	7.052e-05	55.0	COG1547@1|root,COG1547@2|Bacteria,1WKCC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
GDHHQS1_k127_3986497_3	439235.Dalk_1595	2.941e-63	232.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
GDHHQS1_k127_3986497_4	1246459.KB898354_gene5091	6.59e-40	161.0	COG3719@1|root,COG3719@2|Bacteria,1NRPM@1224|Proteobacteria,2U24Q@28211|Alphaproteobacteria,4BCBD@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the RNase T2 family	-	-	3.1.27.1	ko:K01166	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_T2
GDHHQS1_k127_3998725_1	1340493.JNIF01000003_gene2431	5.645e-74	267.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS1_k127_3998725_5	404589.Anae109_0423	7.8e-33	133.0	COG2062@1|root,COG2062@2|Bacteria,1PKQQ@1224|Proteobacteria,43AAX@68525|delta/epsilon subdivisions,2WYNV@28221|Deltaproteobacteria,2Z26S@29|Myxococcales	28221|Deltaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GDHHQS1_k127_3998725_3	1158756.AQXQ01000009_gene1082	5.92e-56	214.0	COG3176@1|root,COG3176@2|Bacteria,1P4U9@1224|Proteobacteria,1T162@1236|Gammaproteobacteria,1X2N2@135613|Chromatiales	135613|Chromatiales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
GDHHQS1_k127_3998725_4	1123257.AUFV01000017_gene3783	6.835e-52	195.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria,1X5QD@135614|Xanthomonadales	135614|Xanthomonadales	I	acetyltransferase	plsC1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS1_k127_3998725_2	671143.DAMO_1129	4.822e-68	239.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_3998725_0	1089553.Tph_c04850	1.686e-95	328.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS1_k127_406195_11	867845.KI911784_gene950	5.352e-35	144.0	COG0642@1|root,COG2205@2|Bacteria	867845.KI911784_gene950|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_406195_16	1121356.AQUW01000004_gene93	1.481e-09	60.0	COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria,22P58@1653|Corynebacteriaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0008150,GO:0040007	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS1_k127_406195_6	316274.Haur_0387	8.763e-78	278.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,375EW@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS1_k127_406195_13	671143.DAMO_2576	2.316e-26	125.0	COG0746@1|root,COG0746@2|Bacteria,2NPYD@2323|unclassified Bacteria	2|Bacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
GDHHQS1_k127_406195_5	370438.PTH_2623	1.132e-88	312.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,260P7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GDHHQS1_k127_406195_9	497964.CfE428DRAFT_4921	3.996e-56	212.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
GDHHQS1_k127_406195_0	395495.Lcho_1343	6.925e-296	930.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,1KN24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS1_k127_406195_17	679897.HMU11120	3.906e-09	70.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
GDHHQS1_k127_406195_15	1123072.AUDH01000008_gene224	3.665e-17	87.0	COG0517@1|root,COG0517@2|Bacteria,1NY5H@1224|Proteobacteria,2U1GG@28211|Alphaproteobacteria,2JX0D@204441|Rhodospirillales	204441|Rhodospirillales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
GDHHQS1_k127_406195_4	279010.BL01169	6.253e-99	335.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_406195_8	314345.SPV1_13629	8.031e-58	227.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS1_k127_406195_14	765869.BDW_09450	1.145e-17	96.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2MT5W@213481|Bdellovibrionales,2WMWV@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_406195_7	652103.Rpdx1_0796	2.849e-59	218.0	COG3303@1|root,COG3303@2|Bacteria,1QXZC@1224|Proteobacteria,2TRV1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_406195_18	1463854.JOHT01000003_gene5900	8.808e-07	61.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS1_k127_406195_12	404589.Anae109_2746	8.808e-33	135.0	COG3005@1|root,COG3005@2|Bacteria,1Q9NJ@1224|Proteobacteria,434HC@68525|delta/epsilon subdivisions,2WYUP@28221|Deltaproteobacteria,2Z0NR@29|Myxococcales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
GDHHQS1_k127_406195_10	290397.Adeh_2105	1.708e-41	159.0	2E533@1|root,32WWG@2|Bacteria,1QAP2@1224|Proteobacteria,4357C@68525|delta/epsilon subdivisions,2WZIC@28221|Deltaproteobacteria,2Z27M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_406195_3	404589.Anae109_1712	5.866e-124	408.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
GDHHQS1_k127_406195_1	404589.Anae109_1713	9.022e-192	633.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	cytochrome c	ccsBA	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
GDHHQS1_k127_406195_2	330214.NIDE2263	3.462e-171	547.0	COG0542@1|root,COG0542@2|Bacteria,3J0AV@40117|Nitrospirae	40117|Nitrospirae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS1_k127_411895_3	8932.XP_005509375.1	9.188e-133	452.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3B98M@33208|Metazoa,3CT8Z@33213|Bilateria,47ZCM@7711|Chordata,492KW@7742|Vertebrata,4GR2M@8782|Aves	33208|Metazoa	O	Thimet oligopeptidase	THOP1	GO:0000209,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016567,GO:0016787,GO:0019538,GO:0023052,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901564	3.4.24.15,3.4.24.16	ko:K01392,ko:K01393	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS1_k127_411895_19	402626.Rpic_4719	4.137e-32	138.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1K0I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS1_k127_411895_2	290397.Adeh_2048	6.88e-156	519.0	COG1449@1|root,COG1449@2|Bacteria,1PUYM@1224|Proteobacteria,42MQP@68525|delta/epsilon subdivisions,2WKP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
GDHHQS1_k127_411895_4	383372.Rcas_0031	1.284e-116	400.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS1_k127_411895_11	1408473.JHXO01000005_gene1472	1.529e-58	211.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
GDHHQS1_k127_411895_12	1121918.ARWE01000001_gene1122	1.367e-53	205.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,43S8F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS1_k127_411895_8	247633.GP2143_17196	3.517e-73	253.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1S4GN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_411895_15	1235457.C404_26045	2.891e-48	188.0	2C2F5@1|root,32WND@2|Bacteria,1N9J7@1224|Proteobacteria,2W66E@28216|Betaproteobacteria,1KB1P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_411895_5	1123253.AUBD01000011_gene2046	1.09e-108	385.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1X43V@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thiol disulfide Interchange Protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS1_k127_411895_10	648757.Rvan_3031	5.199e-60	233.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2U7PM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS1_k127_411895_25	59931.WH7805_06021	7.855e-14	82.0	COG0745@1|root,COG0745@2|Bacteria,1FZXT@1117|Cyanobacteria,1GZVR@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_411895_20	330214.NIDE3490	3.286e-28	126.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
GDHHQS1_k127_411895_21	761193.Runsl_5309	1.401e-25	118.0	COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
GDHHQS1_k127_411895_0	452637.Oter_4634	6.9e-180	584.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,3K7GD@414999|Opitutae	414999|Opitutae	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS1_k127_411895_17	396588.Tgr7_2795	3.137e-45	168.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS1_k127_411895_27	1300345.LF41_2489	1.611e-12	76.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1SBKU@1236|Gammaproteobacteria,1XARM@135614|Xanthomonadales	135614|Xanthomonadales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS1_k127_411895_26	391625.PPSIR1_36002	3.138e-13	77.0	COG1714@1|root,COG1714@2|Bacteria,1NGWF@1224|Proteobacteria,432P0@68525|delta/epsilon subdivisions,2WXX0@28221|Deltaproteobacteria,2YVMY@29|Myxococcales	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS1_k127_411895_1	378806.STAUR_6731	1.053e-173	558.0	COG1028@1|root,COG4221@1|root,COG1028@2|Bacteria,COG4221@2|Bacteria,1R4BM@1224|Proteobacteria,42PS2@68525|delta/epsilon subdivisions,2WJJK@28221|Deltaproteobacteria,2YU82@29|Myxococcales	28221|Deltaproteobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS1_k127_411895_30	1449355.JQNR01000005_gene4931	0.0003108	48.0	COG3620@1|root,COG3620@2|Bacteria,2IKRP@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
GDHHQS1_k127_411895_6	886293.Sinac_1713	2.321e-106	358.0	COG1301@1|root,COG1301@2|Bacteria,2IYUE@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
GDHHQS1_k127_411895_22	1122939.ATUD01000006_gene1643	1.398e-19	103.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_411895_18	502025.Hoch_6700	1.045e-34	146.0	2DX1E@1|root,342YI@2|Bacteria,1NZD7@1224|Proteobacteria,43BY2@68525|delta/epsilon subdivisions,2X78W@28221|Deltaproteobacteria,2YWTV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_411895_13	448385.sce2857	3.227e-49	189.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,43BF8@68525|delta/epsilon subdivisions,2X6TM@28221|Deltaproteobacteria,2YU7G@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS1_k127_411895_28	153721.MYP_2925	1.969e-08	68.0	COG1409@1|root,COG1409@2|Bacteria,4NGXX@976|Bacteroidetes,47PZR@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS1_k127_411895_23	929712.KI912613_gene3999	1.068e-18	89.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS1_k127_411895_7	945713.IALB_0750	1.056e-76	275.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
GDHHQS1_k127_411895_29	1206737.BAGF01000150_gene6127	1.127e-06	62.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FUX8@85025|Nocardiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS1_k127_411895_14	1144275.COCOR_06454	1.472e-48	183.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,43BK7@68525|delta/epsilon subdivisions,2X5W4@28221|Deltaproteobacteria,2Z37Z@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS1_k127_411895_9	671143.DAMO_1059	1.376e-64	241.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GDHHQS1_k127_411895_24	765869.BDW_06140	2.662e-14	80.0	COG3932@1|root,COG3932@2|Bacteria,1Q4G9@1224|Proteobacteria,433GM@68525|delta/epsilon subdivisions,2MTZ5@213481|Bdellovibrionales,2WY27@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
GDHHQS1_k127_411895_16	264462.Bd1016	1.244e-47	176.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42UYD@68525|delta/epsilon subdivisions,2MUPZ@213481|Bdellovibrionales,2WR5I@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS1_k127_4314602_0	1125863.JAFN01000001_gene209	8.925e-120	409.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
GDHHQS1_k127_4314602_2	304371.MCP_1390	0.0001174	55.0	arCOG13226@1|root,arCOG13226@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4314602_1	1552758.NC00_05625	1.108e-13	77.0	28RNU@1|root,2ZE1H@2|Bacteria,1P6CR@1224|Proteobacteria,1SUXE@1236|Gammaproteobacteria,1X8FD@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4393490_2	518766.Rmar_0357	9.901e-05	56.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
GDHHQS1_k127_4393490_1	1121335.Clst_1392	6.26e-26	116.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WIJY@541000|Ruminococcaceae	186801|Clostridia	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	arlR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_4460590_0	204669.Acid345_1271	6.742e-136	441.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
GDHHQS1_k127_4463141_1	1210884.HG799475_gene15234	1.098e-60	216.0	COG4102@1|root,COG4102@2|Bacteria,2IYDS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS1_k127_4463141_0	1123508.JH636442_gene4052	2.549e-141	463.0	COG2010@1|root,COG2010@2|Bacteria,2IXUQ@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS1_k127_4537000_2	1047013.AQSP01000128_gene418	1.83e-47	188.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS1_k127_4537000_6	1346791.M529_18270	0.0002358	54.0	COG0457@1|root,COG0457@2|Bacteria,1PDUB@1224|Proteobacteria,2TTYN@28211|Alphaproteobacteria,2K0P8@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21
GDHHQS1_k127_4537000_5	856793.MICA_411	1.115e-05	58.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1NEA6@1224|Proteobacteria	1224|Proteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_4537000_4	883081.HMPREF9698_00369	6.1e-10	72.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,27GEI@186828|Carnobacteriaceae	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS1_k127_4537000_1	751945.Theos_1408	6.685e-80	293.0	COG1702@1|root,COG1702@2|Bacteria,1WIK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	KH_1,LAGLIDADG_3,PhoH
GDHHQS1_k127_4537000_0	357808.RoseRS_4460	1.718e-133	457.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
GDHHQS1_k127_4537000_3	330214.NIDE1046	7.137e-31	128.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	barA	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS1_k127_458700_0	1906.SFRA_32165	1.611e-66	232.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,2GK6D@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fum	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
GDHHQS1_k127_458700_1	1379698.RBG1_1C00001G0513	4.151e-49	198.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GDHHQS1_k127_4812607_0	1382306.JNIM01000001_gene4139	2.922e-62	218.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_4812607_5	383372.Rcas_3604	1.66e-14	78.0	COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5,PAS_9
GDHHQS1_k127_4812607_4	379731.PST_2043	1.519e-16	88.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,1SBRX@1236|Gammaproteobacteria,1Z16X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	CmpX protein	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
GDHHQS1_k127_4812607_8	573413.Spirs_2360	2.972e-05	57.0	COG4254@1|root,COG4254@2|Bacteria,2J9KS@203691|Spirochaetes	203691|Spirochaetes	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS1_k127_4812607_3	756067.MicvaDRAFT_0355	1.82e-18	91.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1G2P9@1117|Cyanobacteria,1H843@1150|Oscillatoriales	1117|Cyanobacteria	MT	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
GDHHQS1_k127_4812607_6	234267.Acid_6515	1.58e-06	64.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,3Y2EZ@57723|Acidobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF11,DUF4347,DUF5122,He_PIG,SBBP
GDHHQS1_k127_4812607_9	1227349.C170_08355	4.229e-05	60.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae	91061|Bacilli	O	CarboxypepD_reg-like domain	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
GDHHQS1_k127_4812607_7	1191523.MROS_0377	4.726e-06	63.0	COG2911@1|root,COG4886@1|root,COG2911@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,Flg_new,LRR_5
GDHHQS1_k127_4812607_2	1379698.RBG1_1C00001G1818	1.436e-21	111.0	COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4812607_1	1123399.AQVE01000001_gene472	4.388e-23	115.0	29I4R@1|root,3051R@2|Bacteria,1RDT9@1224|Proteobacteria,1SI66@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4812607_10	483219.LILAB_17465	0.0004015	53.0	COG4254@1|root,COG4254@2|Bacteria,1QX4F@1224|Proteobacteria,43BX2@68525|delta/epsilon subdivisions,2X77V@28221|Deltaproteobacteria,2YX6H@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS1_k127_4812607_11	192875.XP_004342595.1	0.0006116	51.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	ko:K01691	ko04310,map04310	-	-	-	ko00000,ko00001	-	-	-	EGF_2,WIF
GDHHQS1_k127_4878044_0	1379698.RBG1_1C00001G0364	6.257e-117	388.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS1_k127_4878044_2	671143.DAMO_1095	8.179e-55	201.0	COG1392@1|root,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS1_k127_4878044_1	330214.NIDE2415	3.182e-67	244.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,3J0K5@40117|Nitrospirae	2|Bacteria	FP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ppx	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K07012	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000,ko02048	-	-	-	HD,Helicase_C,Ppx-GppA,Response_reg
GDHHQS1_k127_493988_13	232348.ADXL01000072_gene150	4.045e-08	55.0	COG1189@1|root,COG1189@2|Bacteria,1G001@1117|Cyanobacteria,1GZPP@1129|Synechococcus	1117|Cyanobacteria	J	FtsJ-like methyltransferase	tly	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS1_k127_493988_8	497964.CfE428DRAFT_0231	8.8e-55	199.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_493988_2	1282360.ABAC460_19840	1.101e-182	584.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS1_k127_493988_11	1298863.AUEP01000007_gene453	4.539e-20	102.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DQ0Q@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_493988_9	1235792.C808_01935	3.481e-29	137.0	COG1083@1|root,COG1083@2|Bacteria,1UDY4@1239|Firmicutes,25ISH@186801|Clostridia,27SNB@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
GDHHQS1_k127_493988_14	1385521.N803_01035	4.173e-05	56.0	COG3307@1|root,COG3307@2|Bacteria,2HXGD@201174|Actinobacteria,4FGJU@85021|Intrasporangiaceae	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_493988_6	1121033.AUCF01000009_gene1058	5.553e-92	328.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2U3H1@28211|Alphaproteobacteria,2JR8A@204441|Rhodospirillales	204441|Rhodospirillales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS1_k127_493988_7	1121033.AUCF01000009_gene1059	2.012e-56	216.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2UA8A@28211|Alphaproteobacteria,2JTQP@204441|Rhodospirillales	204441|Rhodospirillales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS1_k127_493988_5	697282.Mettu_1267	4.586e-96	328.0	29TUE@1|root,30F2T@2|Bacteria,1NV09@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
GDHHQS1_k127_493988_0	697282.Mettu_1266	5.015e-213	676.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,1RPZX@1236|Gammaproteobacteria,1XES8@135618|Methylococcales	135618|Methylococcales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS1_k127_493988_1	1094715.CM001373_gene376	2.879e-211	689.0	COG0037@1|root,COG0037@2|Bacteria,1R4D0@1224|Proteobacteria,1RRVY@1236|Gammaproteobacteria,1JF8W@118969|Legionellales	118969|Legionellales	D	N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_493988_4	1244869.H261_13990	1.267e-124	421.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,2JPEX@204441|Rhodospirillales	28211|Alphaproteobacteria	C	magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase	bchE	GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Fer4_12,Radical_SAM
GDHHQS1_k127_493988_3	237368.SCABRO_03643	2.91e-138	447.0	COG1086@1|root,COG1086@2|Bacteria,2IWVA@203682|Planctomycetes	203682|Planctomycetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
GDHHQS1_k127_493988_10	477974.Daud_1777	1.944e-26	115.0	COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,24HWM@186801|Clostridia,264G2@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
GDHHQS1_k127_494080_0	671143.DAMO_1468	1.015e-39	154.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS1_k127_497232_22	390989.JOEG01000011_gene373	2.729e-07	63.0	COG0477@1|root,COG2814@2|Bacteria,2HCHA@201174|Actinobacteria,4DGRS@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
GDHHQS1_k127_497232_9	861299.J421_1916	4.89e-48	181.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_1916|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_497232_6	483219.LILAB_04825	2.71e-73	272.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2YYPF@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS1_k127_497232_20	1242864.D187_007281	5.679e-09	68.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Porin_O_P
GDHHQS1_k127_497232_7	398512.JQKC01000030_gene4385	1.319e-59	218.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHXD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
GDHHQS1_k127_497232_17	1216976.AX27061_4321	6.508e-19	99.0	COG1525@1|root,COG1525@2|Bacteria,1PRMF@1224|Proteobacteria,2VX3N@28216|Betaproteobacteria,3T44Q@506|Alcaligenaceae	28216|Betaproteobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
GDHHQS1_k127_497232_16	443144.GM21_2395	1.843e-21	107.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2X5PV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
GDHHQS1_k127_497232_21	1144275.COCOR_07689	2.178e-07	65.0	COG4225@1|root,COG4225@2|Bacteria,1NQTS@1224|Proteobacteria,4321U@68525|delta/epsilon subdivisions,2WX0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
GDHHQS1_k127_497232_11	404380.Gbem_1080	4.806e-43	182.0	COG3979@1|root,COG4447@1|root,COG3979@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.132,3.2.1.14,3.2.1.17	ko:K01183,ko:K01233,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334,R02833	RC00467	ko00000,ko00001,ko01000	-	CBM15,GH18	-	CBM_5_12,Glyco_hydro_18,LPMO_10,fn3
GDHHQS1_k127_497232_3	448385.sce1586	7.856e-92	337.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_497232_19	521393.JH806632_gene45	2.33e-14	87.0	COG3291@1|root,COG3291@2|Bacteria,2H200@201174|Actinobacteria,4D4TJ@85005|Actinomycetales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_497232_15	537013.CLOSTMETH_01497	2.849e-31	130.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3WJZD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS1_k127_497232_8	428125.CLOLEP_00067	4.99e-57	219.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS1_k127_497232_5	316067.Geob_0785	4.012e-76	280.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS1_k127_497232_1	264732.Moth_0850	1.311e-96	344.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,42EUU@68295|Thermoanaerobacterales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS1_k127_497232_2	319795.Dgeo_0256	5.837e-96	342.0	COG2805@1|root,COG2805@2|Bacteria,1WI5S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_497232_13	5741.EDO80901	1.479e-38	153.0	COG1428@1|root,KOG3877@2759|Eukaryota	2759|Eukaryota	F	mitochondrial electron transport, NADH to ubiquinone	-	-	2.7.1.76	ko:K10353	ko00230,ko01100,map00230,map01100	-	R02089	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
GDHHQS1_k127_497232_18	743299.Acife_0635	2.153e-18	94.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,2NCAI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS1_k127_497232_4	1303518.CCALI_02390	3.648e-91	321.0	COG0079@1|root,COG0079@2|Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_497232_10	1485543.JMME01000001_gene1457	1.123e-46	190.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4H4MX@909932|Negativicutes	909932|Negativicutes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS1_k127_497232_14	1283299.AUKG01000001_gene3035	2.224e-31	138.0	COG0204@1|root,COG0240@1|root,COG0204@2|Bacteria,COG0240@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS1_k127_497232_12	1316936.K678_11101	1.009e-40	166.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,2JR06@204441|Rhodospirillales	204441|Rhodospirillales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS1_k127_497232_23	215803.DB30_5681	0.0009394	52.0	COG0457@1|root,COG2013@1|root,COG0457@2|Bacteria,COG2013@2|Bacteria,1P3IM@1224|Proteobacteria,431ZR@68525|delta/epsilon subdivisions,2WWC2@28221|Deltaproteobacteria,2YVCM@29|Myxococcales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,TPR_16,TPR_19,TPR_8
GDHHQS1_k127_497232_0	644282.Deba_1878	3.335e-118	407.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS1_k127_5011183_5	471855.Shel_24410	1.132e-41	162.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CUTC@84998|Coriobacteriia	84998|Coriobacteriia	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
GDHHQS1_k127_5011183_0	1243664.CAVL020000005_gene310	1.541e-158	530.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS1_k127_5011183_1	1234664.AMRO01000074_gene2862	2.931e-105	353.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1WFVV@129337|Geobacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS1_k127_5011183_6	861530.ALOZ01000056_gene1502	2.963e-30	123.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,4GZ42@90964|Staphylococcaceae	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS1_k127_5011183_10	888439.HMPREF9240_00191	1.233e-09	61.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4D6F8@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS1_k127_5011183_4	1238182.C882_1246	7.763e-45	169.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2JRWF@204441|Rhodospirillales	204441|Rhodospirillales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS1_k127_5011183_9	269799.Gmet_1051	7.797e-11	67.0	COG4190@1|root,COG4190@2|Bacteria,1Q116@1224|Proteobacteria,4371C@68525|delta/epsilon subdivisions,2WYD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5011183_8	1283300.ATXB01000001_gene284	6.944e-11	66.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,1SCAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5011183_7	251221.35212131	1.034e-12	74.0	2AVYW@1|root,31MT4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5011183_2	1232410.KI421421_gene3462	3.688e-86	297.0	COG1850@1|root,COG1917@1|root,COG1850@2|Bacteria,COG1917@2|Bacteria,1MWEB@1224|Proteobacteria	1224|Proteobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	mtnW	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
GDHHQS1_k127_5011183_3	1203554.HMPREF1476_01691	6.686e-50	187.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2W8XV@28216|Betaproteobacteria,4PRA4@995019|Sutterellaceae	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
GDHHQS1_k127_5040724_2	1121104.AQXH01000001_gene1782	1.625e-43	180.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS1_k127_5040724_0	237368.SCABRO_01638	6.952e-104	370.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS1_k127_5040724_4	1123290.AUDQ01000004_gene311	6.99e-11	75.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HNM5@91061|Bacilli,26ICG@186818|Planococcaceae	91061|Bacilli	S	UvrB/uvrC motif	-	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
GDHHQS1_k127_5040724_1	292459.STH3134	7.985e-76	266.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia	186801|Clostridia	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
GDHHQS1_k127_5040724_3	247490.KSU1_D0151	2.275e-22	107.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5040724_5	1075090.GOAMR_26_00830	1.217e-07	55.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4GADA@85026|Gordoniaceae	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
GDHHQS1_k127_5042493_2	1244869.H261_08013	3.448e-05	53.0	COG4249@1|root,COG4249@2|Bacteria,1REY7@1224|Proteobacteria,2U87J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14,Sel1
GDHHQS1_k127_5042493_1	234267.Acid_2761	2.638e-110	370.0	COG1819@1|root,COG1819@2|Bacteria,3Y3H9@57723|Acidobacteria	2|Bacteria	CG	PFAM glycosyl transferase, family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
GDHHQS1_k127_5042493_0	1242864.D187_000755	5.968e-129	442.0	COG0366@1|root,COG4945@1|root,COG0366@2|Bacteria,COG4945@2|Bacteria,1MU90@1224|Proteobacteria,433VR@68525|delta/epsilon subdivisions,2X3PU@28221|Deltaproteobacteria,2YWT2@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
GDHHQS1_k127_5042493_3	134676.ACPL_3683	0.0005876	47.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4DB3P@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372,PUD
GDHHQS1_k127_5472302_3	1121422.AUMW01000012_gene2968	5.046e-67	235.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,26064@186807|Peptococcaceae	186801|Clostridia	J	TIGRFAM Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS1_k127_5472302_17	521098.Aaci_2922	3.467e-08	60.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli	91061|Bacilli	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_5472302_9	208439.AJAP_24265	6.975e-33	147.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DYIP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS1_k127_5472302_2	1408473.JHXO01000002_gene3933	6.633e-70	245.0	COG0670@1|root,COG0670@2|Bacteria,4NG98@976|Bacteroidetes,2FQXN@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
GDHHQS1_k127_5472302_4	742742.HMPREF9452_01974	1.396e-51	196.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CUH5@84998|Coriobacteriia	84998|Coriobacteriia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_5472302_8	522306.CAP2UW1_1741	2.545e-35	150.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KPSW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA_2,ClpB_D2-small
GDHHQS1_k127_5472302_19	1122244.AUGF01000069_gene1927	0.0001175	53.0	2ED69@1|root,3372Y@2|Bacteria,1NHBV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5472302_0	1123371.ATXH01000035_gene1999	4.525e-142	465.0	COG0001@1|root,COG0001@2|Bacteria,2GGR9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_5472302_1	264732.Moth_1246	4.051e-129	419.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
GDHHQS1_k127_5472302_5	861299.J421_3045	6.046e-49	198.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	861299.J421_3045|-	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS1_k127_5472302_13	1449076.JOOE01000002_gene706	9.459e-18	89.0	COG0596@1|root,COG0596@2|Bacteria,1QU30@1224|Proteobacteria,2TSNY@28211|Alphaproteobacteria,2KCXI@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS1_k127_5472302_16	1189612.A33Q_2470	3.263e-08	64.0	COG4538@1|root,COG4538@2|Bacteria,4NX66@976|Bacteroidetes,47XBQ@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS1_k127_5472302_7	4641.GSMUA_Achr7P01430_001	2.846e-37	152.0	COG1670@1|root,2RXXF@2759|Eukaryota,37TVE@33090|Viridiplantae,3GI8H@35493|Streptophyta,3KRM1@4447|Liliopsida	35493|Streptophyta	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS1_k127_5472302_15	1121920.AUAU01000012_gene2653	3.027e-08	64.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
GDHHQS1_k127_5472302_6	1128421.JAGA01000002_gene1594	1.285e-37	156.0	COG3230@1|root,COG3230@2|Bacteria	2|Bacteria	-	-	-	-	1.14.99.58	ko:K07215	ko00860,map00860	-	-	-	ko00000,ko00001,ko01000	-	-	-	Heme_oxygenase
GDHHQS1_k127_5472302_11	224911.27353456	2.584e-24	112.0	COG5012@1|root,COG5012@2|Bacteria,1Q3Q4@1224|Proteobacteria,2VADT@28211|Alphaproteobacteria,3K5KP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding_2
GDHHQS1_k127_5472302_14	1122244.AUGF01000001_gene1771	1.214e-16	92.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,3NSWJ@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT,Sel1
GDHHQS1_k127_5472302_10	1089553.Tph_c10280	4.104e-27	118.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS1_k127_5472302_18	1232452.BAIB02000001_gene18	1.595e-05	48.0	2BZDJ@1|root,2ZPU3@2|Bacteria,1W5XA@1239|Firmicutes,255BW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5472302_12	246194.CHY_2327	3.949e-18	85.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,42EPJ@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS1_k127_5526881_13	886293.Sinac_1703	1.299e-14	85.0	COG0515@1|root,COG0515@2|Bacteria,2IZ0Z@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS1_k127_5526881_3	398767.Glov_3125	3.157e-99	340.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS1_k127_5526881_0	671143.DAMO_2705	7.389e-136	475.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS1_k127_5526881_1	517418.Ctha_2557	4.343e-126	430.0	COG1009@1|root,COG1009@2|Bacteria,1FDAG@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS1_k127_5526881_9	383372.Rcas_2095	9.986e-25	113.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,375VH@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS1_k127_5526881_11	316274.Haur_4986	1.224e-21	104.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi,375K1@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS1_k127_5526881_10	1379698.RBG1_1C00001G1875	2.115e-22	103.0	COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00337,ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
GDHHQS1_k127_5526881_4	880073.Calab_2689	4.364e-84	309.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS1_k127_5526881_2	696369.KI912183_gene850	1.026e-124	411.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,24EDV@186801|Clostridia,260QS@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS1_k127_5526881_12	986075.CathTA2_2802	2.849e-20	97.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS1_k127_5526881_6	867903.ThesuDRAFT_02259	2.434e-58	212.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,24GH5@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS1_k127_5526881_7	1120973.AQXL01000110_gene1002	8.381e-51	196.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,4HHGV@91061|Bacilli,278C9@186823|Alicyclobacillaceae	91061|Bacilli	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
GDHHQS1_k127_5526881_14	264462.Bd0055	0.000877	44.0	COG2036@1|root,33IMA@2|Bacteria,1Q233@1224|Proteobacteria,437QD@68525|delta/epsilon subdivisions,2MUDJ@213481|Bdellovibrionales,2X2YX@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
GDHHQS1_k127_5526881_8	1382306.JNIM01000001_gene3830	1.776e-48	181.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_5526881_5	517418.Ctha_0236	1.701e-64	253.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS1_k127_5550369_22	1121890.AUDO01000011_gene410	9.092e-25	105.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2NSRJ@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS1_k127_5550369_16	313628.LNTAR_13927	8.931e-53	196.0	COG0284@1|root,COG0284@2|Bacteria	2|Bacteria	F	orotidine-5'-phosphate decarboxylase activity	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
GDHHQS1_k127_5550369_17	871968.DESME_12110	2.877e-52	201.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS1_k127_5550369_6	72658.Bostr.0697s0118.1.p	2.347e-98	336.0	COG0151@1|root,KOG0237@2759|Eukaryota,37QAB@33090|Viridiplantae,3G9H5@35493|Streptophyta,3HYEJ@3699|Brassicales	35493|Streptophyta	F	Phosphoribosylformylglycinamidine cyclo-ligase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS1_k127_5550369_2	1120954.ATXE01000003_gene489	3.746e-144	496.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4DP1R@85009|Propionibacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS1_k127_5550369_3	1304888.ATWF01000001_gene659	1.65e-133	435.0	COG0505@1|root,COG0505@2|Bacteria,2GF07@200930|Deferribacteres	200930|Deferribacteres	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS1_k127_5550369_0	589924.Ferp_0317	0.0	1291.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS1_k127_5550369_26	1121439.dsat_1146	5.587e-17	94.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WQCD@28221|Deltaproteobacteria,2MA4N@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
GDHHQS1_k127_5550369_23	264462.Bd2432	2.444e-20	99.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,42W41@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS1_k127_5550369_19	526227.Mesil_2000	3.544e-37	143.0	COG0735@1|root,COG0735@2|Bacteria,1WJYT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS1_k127_5550369_33	518766.Rmar_2640	2.977e-07	62.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4PIDX@976|Bacteroidetes,1FK2B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
GDHHQS1_k127_5550369_27	1144275.COCOR_07085	9.686e-12	73.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria,2YZ6J@29|Myxococcales	28221|Deltaproteobacteria	U	ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS1_k127_5550369_21	502025.Hoch_4648	2.56e-28	122.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,43BH4@68525|delta/epsilon subdivisions,2WRU4@28221|Deltaproteobacteria,2YVB3@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
GDHHQS1_k127_5550369_4	518766.Rmar_0876	4.662e-122	415.0	COG1629@1|root,COG4771@2|Bacteria,4PIBS@976|Bacteroidetes,1FJ71@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS1_k127_5550369_32	1352941.M877_32615	8.239e-08	66.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GDHHQS1_k127_5550369_35	926569.ANT_18390	0.0001454	55.0	COG4485@1|root,COG4485@2|Bacteria,2G6VS@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5550369_30	926550.CLDAP_09690	1.54e-08	68.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS1_k127_5550369_12	756272.Plabr_1573	1.267e-57	210.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_5550369_25	404589.Anae109_0678	6.567e-18	94.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2Z31A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GDHHQS1_k127_5550369_13	926550.CLDAP_22130	2.881e-56	203.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS1_k127_5550369_20	1313304.CALK_0381	2.216e-29	126.0	COG0565@1|root,COG0565@2|Bacteria	2|Bacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS1_k127_5550369_10	756499.Desde_2801	6.372e-65	236.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,2611X@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS1_k127_5550369_29	243231.GSU3226	3.381e-10	68.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,42YEH@68525|delta/epsilon subdivisions,2WU0R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_5550369_14	404589.Anae109_1846	8.486e-56	214.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS1_k127_5550369_5	1125863.JAFN01000001_gene1528	7.242e-120	416.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_5550369_15	269799.Gmet_1869	2.938e-54	204.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS1_k127_5550369_31	880073.Calab_1263	6.015e-08	63.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_5550369_28	402881.Plav_3368	3.95e-11	71.0	COG3677@1|root,COG3677@2|Bacteria,1R999@1224|Proteobacteria,2UD3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
GDHHQS1_k127_5550369_11	1158338.JNLJ01000001_gene945	6.094e-62	230.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
GDHHQS1_k127_5550369_8	123214.PERMA_1839	1.222e-90	332.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_5550369_18	404589.Anae109_0899	6.077e-50	186.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5550369_9	909663.KI867150_gene213	5.528e-90	314.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_5550369_24	794903.OPIT5_00530	5.298e-19	100.0	2FAF9@1|root,342PH@2|Bacteria,46WU3@74201|Verrucomicrobia,3K8GZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5550369_1	1121405.dsmv_3558	8.019e-145	466.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
GDHHQS1_k127_5550369_7	1121405.dsmv_3559	8.276e-97	331.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
GDHHQS1_k127_5556864_2	1244869.H261_13910	2.952e-91	315.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2JR9T@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_5556864_7	696747.NIES39_N00220	1.437e-79	299.0	COG1132@1|root,COG1132@2|Bacteria,1G02Q@1117|Cyanobacteria,1H8KQ@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_5556864_4	1173026.Glo7428_1305	8.552e-88	300.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1G1R7@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
GDHHQS1_k127_5556864_8	1397666.RS24_00799	2.753e-79	286.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,4BS92@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.7.38,4.1.2.52	ko:K00979,ko:K02510	ko00350,ko00540,ko01100,ko01120,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R03351,R11396	RC00152,RC00307,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
GDHHQS1_k127_5556864_3	207559.Dde_3687	5.901e-89	312.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMSQ@28221|Deltaproteobacteria,2MGAJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM acylneuraminate cytidylyltransferase	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS1_k127_5556864_0	1244869.H261_07863	3.891e-140	467.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2U80G@28211|Alphaproteobacteria,2JWB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_5556864_6	1244869.H261_07848	3.263e-85	308.0	COG1028@1|root,COG1028@2|Bacteria,1R3ZC@1224|Proteobacteria,2TUI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS1_k127_5556864_1	1244869.H261_07843	9.861e-128	419.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS1_k127_5556864_5	1244869.H261_07833	4.618e-86	309.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U8UZ@28211|Alphaproteobacteria,2JX6Y@204441|Rhodospirillales	204441|Rhodospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS1_k127_5556864_11	1229520.ADIAL_0757	2.077e-37	151.0	COG0279@1|root,COG0279@2|Bacteria,1V610@1239|Firmicutes,4HJH3@91061|Bacilli,27GHD@186828|Carnobacteriaceae	91061|Bacilli	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GDHHQS1_k127_5556864_10	443143.GM18_0657	1.21e-50	191.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K16555	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS1_k127_5556864_13	1500894.JQNN01000001_gene3724	2.11e-15	89.0	COG0399@1|root,COG0399@2|Bacteria,1REP8@1224|Proteobacteria,2VX4S@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_5556864_14	1187851.A33M_0669	1.109e-13	85.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
GDHHQS1_k127_5556864_12	75379.Tint_1512	7.41e-22	108.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2WEGG@28216|Betaproteobacteria,1KPKH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_5556864_9	266117.Rxyl_2692	5.569e-54	216.0	COG0438@1|root,COG0438@2|Bacteria,2HUAV@201174|Actinobacteria,4CTZU@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GDHHQS1_k127_5640955_5	498761.HM1_2050	6.673e-30	124.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS1_k127_5640955_3	521098.Aaci_1269	4.113e-76	267.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,2797Y@186823|Alicyclobacillaceae	91061|Bacilli	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS1_k127_5640955_2	316067.Geob_0774	7.476e-104	359.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
GDHHQS1_k127_5640955_0	234267.Acid_7316	9.138e-120	402.0	COG0769@1|root,COG0769@2|Bacteria,3Y38W@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_5640955_4	443143.GM18_3891	1.567e-75	272.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,43TX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_5640955_1	1122135.KB893146_gene1604	3.227e-112	373.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS1_k127_5640955_6	1454007.JAUG01000061_gene465	3.193e-06	59.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_564344_0	1356852.N008_07620	1.303e-74	271.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia	976|Bacteroidetes	L	Superfamily I DNA and RNA	recD2_4	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011
GDHHQS1_k127_5660169_12	1449126.JQKL01000004_gene577	3.635e-11	64.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,269HK@186813|unclassified Clostridiales	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	ccmL	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS1_k127_5660169_9	913865.DOT_6144	6.312e-29	119.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,265RN@186807|Peptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GDHHQS1_k127_5660169_5	717605.Theco_2018	4.229e-56	208.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,4HAG3@91061|Bacilli,26T3U@186822|Paenibacillaceae	91061|Bacilli	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	2242	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
GDHHQS1_k127_5660169_2	880072.Desac_1975	8.821e-75	259.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2MQRG@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS1_k127_5660169_13	1448139.AI20_17325	2.203e-07	60.0	COG3700@1|root,COG3700@2|Bacteria,1PRRA@1224|Proteobacteria,1RP0N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the class B bacterial acid phosphatase family	aphA	GO:0003674,GO:0003824,GO:0003993,GO:0004647,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030288,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0044237,GO:0044464,GO:0048037	3.1.3.2	ko:K03788	ko00740,ko01100,map00740,map01100	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_4476,iYL1228.KPN_04442	Acid_phosphat_B
GDHHQS1_k127_5660169_0	335543.Sfum_0741	7.667e-86	302.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2MQ91@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
GDHHQS1_k127_5660169_11	1040987.AZUY01000042_gene88	2.383e-14	84.0	COG0463@1|root,COG0500@1|root,COG0726@1|root,COG0463@2|Bacteria,COG0500@2|Bacteria,COG0726@2|Bacteria,1R7PS@1224|Proteobacteria,2TU1B@28211|Alphaproteobacteria,43PBY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GMQ	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,NodS,Polysacc_deac_1
GDHHQS1_k127_5660169_10	671143.DAMO_2823	4.093e-27	124.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS1_k127_5660169_8	97137.C821_01425	9.395e-34	134.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS1_k127_5660169_7	1123371.ATXH01000004_gene1687	1.501e-35	147.0	COG0102@1|root,COG0102@2|Bacteria,2GH50@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS1_k127_5660169_1	360107.CHAB381_1552	1.188e-79	285.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,42MV8@68525|delta/epsilon subdivisions,2YMAE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS1_k127_5660169_4	391625.PPSIR1_11225	2.448e-58	222.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria	1224|Proteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
GDHHQS1_k127_5660169_3	1454004.AW11_01907	3.865e-59	216.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,1KQE3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
GDHHQS1_k127_5660169_6	478741.JAFS01000002_gene924	2.666e-55	198.0	COG1562@1|root,COG1562@2|Bacteria,46YWE@74201|Verrucomicrobia,37G7E@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
GDHHQS1_k127_5724752_11	1007103.AFHW01000120_gene694	7.773e-42	171.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli,274WU@186822|Paenibacillaceae	91061|Bacilli	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
GDHHQS1_k127_5724752_4	1000565.METUNv1_03362	2.058e-102	352.0	2ESTR@1|root,33KC5@2|Bacteria,1NHBB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5724752_14	1123388.AQWU01000021_gene1822	2.997e-24	109.0	COG5502@1|root,COG5502@2|Bacteria,1WJW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
GDHHQS1_k127_5724752_17	1123360.thalar_01492	6.941e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcrX	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_5724752_3	644966.Tmar_1118	1.088e-119	398.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,2481K@186801|Clostridia	186801|Clostridia	C	FAD dependent oxidoreductase	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thi4
GDHHQS1_k127_5724752_16	696369.KI912183_gene2583	2.215e-20	93.0	COG2440@1|root,COG2440@2|Bacteria,1V6DH@1239|Firmicutes,24NRC@186801|Clostridia,266WY@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
GDHHQS1_k127_5724752_9	1380394.JADL01000004_gene6061	3.4e-46	185.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
GDHHQS1_k127_5724752_7	398580.Dshi_3307	6.447e-69	253.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
GDHHQS1_k127_5724752_13	944479.JQLX01000014_gene1511	2.991e-29	123.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2M6HK@213113|Desulfurellales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS1_k127_5724752_15	518766.Rmar_0108	1.23e-21	109.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,4NHCH@976|Bacteroidetes,1FJI1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
GDHHQS1_k127_5724752_6	469371.Tbis_3424	1.133e-69	249.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS1_k127_5724752_12	1123376.AUIU01000011_gene937	2e-37	150.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
GDHHQS1_k127_5724752_1	517418.Ctha_0693	3.071e-203	646.0	COG0004@1|root,COG0004@2|Bacteria,1FDG1@1090|Chlorobi	1090|Chlorobi	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS1_k127_5724752_0	880073.Calab_3212	2.954e-239	756.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS1_k127_5724752_2	765869.BDW_04795	4.558e-127	422.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2MSMR@213481|Bdellovibrionales,2WIY6@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GDHHQS1_k127_5724752_8	1408224.SAMCCGM7_c4425	3.098e-64	231.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,4B7SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	mocA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_5724752_5	204669.Acid345_2380	2.234e-88	308.0	COG0477@1|root,COG0477@2|Bacteria,3Y334@57723|Acidobacteria,2JIV9@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS1_k127_5724752_18	483219.LILAB_13565	5.934e-06	60.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
GDHHQS1_k127_5724752_19	383372.Rcas_1785	0.0005883	50.0	2DVF3@1|root,33VKH@2|Bacteria,2GBV0@200795|Chloroflexi,375TH@32061|Chloroflexia	32061|Chloroflexia	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
GDHHQS1_k127_5724752_10	1128421.JAGA01000002_gene1545	4.523e-46	187.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd
GDHHQS1_k127_5842782_0	1173027.Mic7113_3322	4.767e-95	317.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1H9RK@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
GDHHQS1_k127_5842782_5	686340.Metal_0358	2.908e-10	70.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S9R6@1236|Gammaproteobacteria,1XFJ7@135618|Methylococcales	135618|Methylococcales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS1_k127_5842782_8	1167006.UWK_02980	0.0003226	51.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MKKC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS1_k127_5842782_4	1184267.A11Q_537	1.648e-14	83.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,42WAH@68525|delta/epsilon subdivisions,2MTKG@213481|Bdellovibrionales,2X5KM@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
GDHHQS1_k127_5842782_3	309807.SRU_1584	1.698e-17	98.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
GDHHQS1_k127_5842782_6	1121104.AQXH01000007_gene465	3.167e-06	60.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS1_k127_5842782_1	483219.LILAB_02640	8.434e-86	298.0	28M67@1|root,2ZAJW@2|Bacteria,1NV1K@1224|Proteobacteria,4382X@68525|delta/epsilon subdivisions,2X3CZ@28221|Deltaproteobacteria,2YVGS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5842782_2	159087.Daro_3751	1.302e-37	160.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2WGZK@28216|Betaproteobacteria,2KW1W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS1_k127_5842782_7	1242864.D187_003663	0.000267	45.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,42ZSC@68525|delta/epsilon subdivisions,2WUTP@28221|Deltaproteobacteria,2YURA@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS1_k127_585874_2	580332.Slit_1240	1.001e-65	237.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria,44WKT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
GDHHQS1_k127_585874_7	1396418.BATQ01000058_gene93	1.681e-25	123.0	COG0500@1|root,COG0500@2|Bacteria,46Z44@74201|Verrucomicrobia,2IUZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS1_k127_585874_5	941449.dsx2_1033	3.781e-30	139.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2M7SY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	smart pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
GDHHQS1_k127_585874_0	1144275.COCOR_07372	8.501e-222	695.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
GDHHQS1_k127_585874_3	448385.sce1438	2.528e-48	177.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
GDHHQS1_k127_585874_1	396588.Tgr7_1960	4.4e-70	255.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1WYZZ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS1_k127_585874_6	867903.ThesuDRAFT_00783	4.166e-28	121.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS1_k127_585874_4	666685.R2APBS1_2903	4.003e-41	156.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1SN7Y@1236|Gammaproteobacteria,1X4R2@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS1_k127_5894448_1	1125863.JAFN01000001_gene2685	3.372e-168	546.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS1_k127_5894448_2	269799.Gmet_3221	6.07e-99	344.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_5894448_12	255470.cbdbA1100	0.0005128	53.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5894448_3	396588.Tgr7_3317	6.272e-75	279.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1WW01@135613|Chromatiales	135613|Chromatiales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS1_k127_5894448_7	397291.C804_01418	2.266e-17	93.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,27JTZ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GDHHQS1_k127_5894448_5	717231.Flexsi_2122	1.91e-70	258.0	COG0706@1|root,COG0706@2|Bacteria,2GF6E@200930|Deferribacteres	200930|Deferribacteres	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS1_k127_5894448_6	1150864.MILUP08_30221	4.427e-22	103.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4DG1Z@85008|Micromonosporales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS1_k127_5894448_8	1121403.AUCV01000034_gene3872	1.068e-10	68.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2MKVK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS1_k127_5894448_9	794903.OPIT5_18230	1.037e-08	59.0	COG0230@1|root,COG0230@2|Bacteria,46XWC@74201|Verrucomicrobia,3K8GI@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS1_k127_5894448_0	204669.Acid345_3520	9.336e-297	922.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria,2JI3Z@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS1_k127_5894448_10	269482.Bcep1808_2756	0.0001422	55.0	COG3307@1|root,COG3307@2|Bacteria,1RA1F@1224|Proteobacteria,2VQ8F@28216|Betaproteobacteria,1K2C4@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Pfam O-Antigen Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
GDHHQS1_k127_5894448_11	98439.AJLL01000005_gene4493	0.0001519	53.0	COG1381@1|root,COG1381@2|Bacteria,1G06V@1117|Cyanobacteria,1JI68@1189|Stigonemataceae	1117|Cyanobacteria	L	Recombination protein O C terminal	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS1_k127_5894448_4	653733.Selin_1382	1.923e-71	244.0	COG0752@1|root,COG0752@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQ	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01878,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360	tRNA-synt_2e
GDHHQS1_k127_5901814_5	1227484.C471_05391	0.0001404	53.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota,23SIB@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GDHHQS1_k127_5901814_2	378806.STAUR_8320	2.533e-27	127.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,43BH4@68525|delta/epsilon subdivisions,2WRU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
GDHHQS1_k127_5901814_3	378806.STAUR_7247	8.88e-20	98.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria,2YZ6J@29|Myxococcales	28221|Deltaproteobacteria	U	ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS1_k127_5901814_4	378806.STAUR_5295	3.044e-08	65.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2Z1BM@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS1_k127_5901814_0	1550073.JROH01000001_gene524	2.581e-47	175.0	COG1670@1|root,COG1670@2|Bacteria,1RK5M@1224|Proteobacteria,2UBIE@28211|Alphaproteobacteria,2K4T5@204457|Sphingomonadales	204457|Sphingomonadales	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS1_k127_5901814_1	588596.U9TPY7	1.411e-32	141.0	2CMKB@1|root,2QQNT@2759|Eukaryota,38EY6@33154|Opisthokonta,3NYMZ@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_601995_0	530564.Psta_2878	4.781e-133	437.0	COG1073@1|root,COG1073@2|Bacteria,2IXK0@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS1_k127_601995_2	335543.Sfum_2322	4.292e-05	57.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
GDHHQS1_k127_601995_1	1123242.JH636435_gene2373	1.621e-06	61.0	COG1657@1|root,COG1657@2|Bacteria,2J2E1@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GDHHQS1_k127_6055555_24	1304880.JAGB01000002_gene1985	8.817e-17	81.0	COG3290@1|root,COG3437@1|root,COG3290@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes	1239|Firmicutes	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9
GDHHQS1_k127_6055555_13	204669.Acid345_0035	1.631e-52	196.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria,2JIGR@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS1_k127_6055555_22	648757.Rvan_1979	1.719e-22	107.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,3N622@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS1_k127_6055555_23	1203606.HMPREF1526_00089	7.452e-21	104.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,36JRD@31979|Clostridiaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS1_k127_6055555_3	1121472.AQWN01000008_gene1991	1.792e-168	546.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,2609R@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS1_k127_6055555_28	1242864.D187_010090	1.93e-11	77.0	COG0745@1|root,COG0745@2|Bacteria	1242864.D187_010090|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6055555_12	118166.JH976537_gene579	1.947e-82	291.0	COG0005@1|root,COG0005@2|Bacteria,1G1F3@1117|Cyanobacteria,1H85M@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS1_k127_6055555_19	997346.HMPREF9374_1334	3.694e-27	126.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,27C3M@186824|Thermoactinomycetaceae	91061|Bacilli	F	Cytidine and deoxycytidylate deaminase zinc-binding region	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
GDHHQS1_k127_6055555_29	1522072.IL54_3719	0.0001553	53.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,2K5JX@204457|Sphingomonadales	204457|Sphingomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS1_k127_6055555_5	471854.Dfer_4148	1.413e-151	497.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS1_k127_6055555_15	592015.HMPREF1705_00546	1.526e-50	186.0	COG0279@1|root,COG0279@2|Bacteria,3TB1U@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GDHHQS1_k127_6055555_16	591001.Acfer_1654	3.905e-38	156.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H2I5@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
GDHHQS1_k127_6055555_6	580332.Slit_0253	1.158e-130	458.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
GDHHQS1_k127_6055555_4	1267535.KB906767_gene3899	2.16e-161	522.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria,2JI20@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS1_k127_6055555_21	330214.NIDE3093	3.632e-23	114.0	COG1051@1|root,COG1051@2|Bacteria,3J1FA@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS1_k127_6055555_2	1125863.JAFN01000001_gene1604	2.624e-169	563.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS1_k127_6055555_17	1173023.KE650771_gene4375	1.415e-36	156.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5G9@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
GDHHQS1_k127_6055555_26	756067.MicvaDRAFT_2620	2.93e-15	89.0	COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria,1HC33@1150|Oscillatoriales	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS1_k127_6055555_1	477974.Daud_1619	1.308e-176	577.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS1_k127_6055555_0	330214.NIDE1289	1.331e-245	778.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS1_k127_6055555_10	891968.Anamo_1556	1.674e-107	358.0	COG1052@1|root,COG1052@2|Bacteria,3TARR@508458|Synergistetes	508458|Synergistetes	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS1_k127_6055555_11	1408324.JNJK01000017_gene3606	1.372e-83	288.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,27IRE@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
GDHHQS1_k127_6055555_20	696369.KI912183_gene1028	9.783e-24	113.0	COG1216@1|root,COG1216@2|Bacteria,1UJRW@1239|Firmicutes,25F86@186801|Clostridia,262I4@186807|Peptococcaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_6055555_14	521674.Plim_3462	2.797e-52	199.0	COG4198@1|root,COG4198@2|Bacteria,2IX7C@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GDHHQS1_k127_6055555_18	411471.SUBVAR_06424	1.123e-34	147.0	COG1057@1|root,COG1713@1|root,COG1057@2|Bacteria,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24I4S@186801|Clostridia,3WRU1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,HD
GDHHQS1_k127_6055555_8	1454010.JEOE01000001_gene610	7.598e-112	389.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_6055555_27	1120917.AQXM01000059_gene619	1.171e-14	84.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS1_k127_6055555_25	292459.STH436	2.205e-15	85.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS1_k127_6055555_9	1095767.CAHD01000205_gene848	6.04e-111	374.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_6055555_7	1121405.dsmv_0087	2.306e-122	426.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MI2W@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS1_k127_6110128_14	331678.Cphamn1_0814	1.565e-15	82.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
GDHHQS1_k127_6110128_3	123214.PERMA_0986	2.025e-93	321.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G5H0@200783|Aquificae	200783|Aquificae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD
GDHHQS1_k127_6110128_5	1265505.ATUG01000001_gene3898	4.596e-55	216.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2MHQX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
GDHHQS1_k127_6110128_2	1051632.TPY_1594	2.955e-134	475.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS1_k127_6110128_7	1120971.AUCA01000019_gene1099	3.646e-38	166.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,278S5@186823|Alicyclobacillaceae	91061|Bacilli	T	HAMP domain	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GDHHQS1_k127_6110128_0	945713.IALB_2618	6.582e-177	571.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS1_k127_6110128_10	1131269.AQVV01000011_gene2520	2.258e-29	120.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
GDHHQS1_k127_6110128_6	324057.Pjdr2_0444	1.795e-39	160.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,276F7@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS1_k127_6110128_15	694431.DESACE_00730	1.918e-15	91.0	COG1502@1|root,COG1502@2|Bacteria,1RK7U@1224|Proteobacteria,42WC8@68525|delta/epsilon subdivisions,2X6NZ@28221|Deltaproteobacteria,2M75H@213113|Desulfurellales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS1_k127_6110128_17	1284352.AOIG01000012_gene1601	5.126e-08	67.0	COG1502@1|root,COG1502@2|Bacteria,1V5GG@1239|Firmicutes,4HI1E@91061|Bacilli,26XZZ@186822|Paenibacillaceae	91061|Bacilli	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS1_k127_6110128_13	1379698.RBG1_1C00001G1652	1.214e-16	95.0	COG1502@1|root,COG1502@2|Bacteria,2NQ5Z@2323|unclassified Bacteria	2|Bacteria	I	PLD-like domain	comA	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	HHH_3,PLDc_2
GDHHQS1_k127_6110128_11	485913.Krac_1470	1.225e-20	100.0	COG0724@1|root,COG0724@2|Bacteria,2G74A@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS1_k127_6110128_4	1244869.H261_02926	1.264e-55	214.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,2JRM7@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
GDHHQS1_k127_6110128_8	552811.Dehly_1481	5.472e-37	149.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS1_k127_6110128_1	1242864.D187_003987	1.889e-168	552.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS1_k127_6110128_16	529709.PYCH_03710	1.948e-12	78.0	COG0697@1|root,arCOG00278@2157|Archaea,2XUJ2@28890|Euryarchaeota,24365@183968|Thermococci	183968|Thermococci	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS1_k127_6110128_12	517417.Cpar_0535	5.082e-17	83.0	COG3411@1|root,COG3411@2|Bacteria,1FFA6@1090|Chlorobi	1090|Chlorobi	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6110128_9	296591.Bpro_3451	3.21e-30	128.0	COG1309@1|root,COG1309@2|Bacteria,1NDUF@1224|Proteobacteria,2VXMY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS1_k127_6110128_18	338963.Pcar_2126	3.624e-05	56.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,42UQA@68525|delta/epsilon subdivisions,2WQXF@28221|Deltaproteobacteria,43TDQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_6159529_0	886293.Sinac_6931	9.585e-250	782.0	COG4102@1|root,COG4102@2|Bacteria,2IXNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS1_k127_6159529_1	886293.Sinac_3148	6.937e-18	85.0	COG2010@1|root,COG2010@2|Bacteria,2IXU7@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS1_k127_6205495_4	926569.ANT_26880	3.297e-35	155.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6205495_7	1123288.SOV_1c09360	2.544e-11	70.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,4H9IM@909932|Negativicutes	909932|Negativicutes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS1_k127_6205495_1	1415780.JPOG01000001_gene1122	3.96e-52	194.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1X2XE@135614|Xanthomonadales	135614|Xanthomonadales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS1_k127_6205495_8	243277.VC_2423	9.183e-10	65.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SBN6@1236|Gammaproteobacteria,1Y2DJ@135623|Vibrionales	135623|Vibrionales	NU	Pilin (bacterial filament)	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
GDHHQS1_k127_6205495_2	667014.Thein_R0030	3.665e-37	147.0	COG0691@1|root,COG0691@2|Bacteria,2GH3M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS1_k127_6205495_6	1232410.KI421412_gene82	1.022e-13	78.0	COG2026@1|root,COG2026@2|Bacteria,1NP1I@1224|Proteobacteria,437H9@68525|delta/epsilon subdivisions,2WVKQ@28221|Deltaproteobacteria,43V3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GDHHQS1_k127_6205495_0	1123368.AUIS01000027_gene1347	2.361e-155	499.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	L-2-hydroxyglutarate oxidase LhgO	lhgO	GO:0000166,GO:0003674,GO:0003824,GO:0003973,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0016899,GO:0034419,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
GDHHQS1_k127_6205495_5	443143.GM18_2548	1.985e-23	103.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42V7U@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
GDHHQS1_k127_6205495_3	402777.KB235903_gene1089	1.314e-36	141.0	COG3657@1|root,COG3657@2|Bacteria,1G6YT@1117|Cyanobacteria,1HCJV@1150|Oscillatoriales	1117|Cyanobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS1_k127_6206264_17	1173028.ANKO01000074_gene3009	1.339e-45	180.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS1_k127_6206264_20	383372.Rcas_4150	1.194e-29	132.0	COG0745@1|root,COG0745@2|Bacteria,2GBMQ@200795|Chloroflexi,377KX@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_6206264_13	483219.LILAB_04820	2.658e-57	212.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_6206264_8	1242864.D187_002316	3.716e-87	302.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2Z3F9@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS1_k127_6206264_21	1304885.AUEY01000042_gene3597	1.527e-26	116.0	COG0745@1|root,COG0745@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
GDHHQS1_k127_6206264_10	448385.sce4838	1.229e-76	264.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
GDHHQS1_k127_6206264_19	1254432.SCE1572_38930	1.949e-33	133.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,430G9@68525|delta/epsilon subdivisions,2WVW0@28221|Deltaproteobacteria,2YV26@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
GDHHQS1_k127_6206264_12	1242864.D187_007702	1.635e-63	221.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.189	ko:K03824,ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS1_k127_6206264_24	686578.AFFX01000003_gene435	2.625e-22	99.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	iron--sulfur cluster insertion protein erpA	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
GDHHQS1_k127_6206264_26	278957.ABEA03000149_gene4067	7.023e-19	90.0	COG0316@1|root,COG0316@2|Bacteria,46VWZ@74201|Verrucomicrobia,3K8AD@414999|Opitutae	414999|Opitutae	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GDHHQS1_k127_6206264_1	509635.N824_19125	1.566e-255	808.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
GDHHQS1_k127_6206264_6	1144275.COCOR_04182	1.545e-101	358.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS1_k127_6206264_18	1162668.LFE_1798	2.862e-37	152.0	COG1225@1|root,COG1225@2|Bacteria,3J12D@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS1_k127_6206264_14	983917.RGE_38700	9.666e-52	190.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
GDHHQS1_k127_6206264_4	460265.Mnod_1405	9.896e-113	368.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria,1JYZX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	NAD dependent epimerase/dehydratase family	ydfG	-	1.1.1.276,1.1.1.381	ko:K05886,ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
GDHHQS1_k127_6206264_11	1380387.JADM01000002_gene1990	1.604e-64	235.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,1XP2W@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
GDHHQS1_k127_6206264_5	84531.JMTZ01000070_gene1816	1.195e-109	364.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS1_k127_6206264_9	56780.SYN_02199	6.695e-77	265.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,2MS70@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS1_k127_6206264_28	1121904.ARBP01000001_gene5713	1.01e-12	74.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
GDHHQS1_k127_6206264_27	644282.Deba_0905	3.529e-18	97.0	COG1503@1|root,COG1503@2|Bacteria,1NHEV@1224|Proteobacteria,42XGN@68525|delta/epsilon subdivisions,2WTEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
GDHHQS1_k127_6206264_15	1158165.KB898875_gene215	5.975e-50	187.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales	135613|Chromatiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS1_k127_6206264_16	237368.SCABRO_01183	2.255e-47	179.0	COG0607@1|root,COG0607@2|Bacteria,2IZ80@203682|Planctomycetes	203682|Planctomycetes	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
GDHHQS1_k127_6206264_22	1046724.KB889900_gene3205	2.922e-26	118.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,46AKM@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,Rhodanese,ThiF,ThiS
GDHHQS1_k127_6206264_2	1267535.KB906767_gene1049	4.217e-171	561.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
GDHHQS1_k127_6206264_23	545695.TREAZ_1613	1.699e-22	105.0	COG1310@1|root,COG1310@2|Bacteria,2JAFD@203691|Spirochaetes	203691|Spirochaetes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
GDHHQS1_k127_6206264_7	1267534.KB906759_gene1921	4.267e-99	332.0	COG0031@1|root,COG0031@2|Bacteria,3Y39M@57723|Acidobacteria,2JIQR@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS1_k127_6206264_0	1034943.BN1094_01740	5.004e-289	902.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,1SN0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_6206264_3	1242864.D187_000078	1.039e-163	519.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2WP73@28221|Deltaproteobacteria,2YUD6@29|Myxococcales	28221|Deltaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
GDHHQS1_k127_6314141_3	269799.Gmet_0222	6.47e-100	335.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria,43UJ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
GDHHQS1_k127_6314141_9	1379698.RBG1_1C00001G1619	2.811e-65	231.0	COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
GDHHQS1_k127_6314141_13	1279019.ARQK01000040_gene355	3.175e-25	119.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SAEB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Protein involved in electron carrier activity, oxidoreductase activity, protein disulfide oxidoreductase activity, cell redox homeostasis and glycerol ether metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS1_k127_6314141_10	1244869.H261_13925	5.935e-48	183.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2JPNG@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_6314141_7	1121272.KB903253_gene6928	3.663e-92	322.0	COG2303@1|root,COG2303@2|Bacteria,2IHDE@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
GDHHQS1_k127_6314141_1	1131269.AQVV01000001_gene1298	1.286e-197	647.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS1_k127_6314141_5	292459.STH1748	1.042e-97	345.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS1_k127_6314141_14	1380367.JIBC01000003_gene3970	5.139e-23	108.0	COG2230@1|root,COG2230@2|Bacteria,1QZSG@1224|Proteobacteria,2TYDY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_6314141_8	264462.Bd0660	2.612e-75	274.0	2BI6Q@1|root,32CBY@2|Bacteria,1MYDT@1224|Proteobacteria,42T3X@68525|delta/epsilon subdivisions,2MTZ4@213481|Bdellovibrionales,2WPSM@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
GDHHQS1_k127_6314141_12	483219.LILAB_27020	1.294e-28	130.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
GDHHQS1_k127_6314141_4	765952.PUV_07350	1.333e-99	355.0	COG0793@1|root,COG0793@2|Bacteria,2JFSF@204428|Chlamydiae	204428|Chlamydiae	M	Belongs to the chlamydial CPn_1016 CT_858 TC_0248 family	CP_0837	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS1_k127_6314141_11	673860.AciM339_0766	7.752e-42	160.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GDHHQS1_k127_6314141_15	1183377.Py04_1081	7.696e-19	93.0	COG1144@1|root,arCOG01605@2157|Archaea,2XY2F@28890|Euryarchaeota,245HQ@183968|Thermococci	183968|Thermococci	C	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	vorD	-	1.2.7.7	ko:K00188	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
GDHHQS1_k127_6314141_2	1121405.dsmv_1953	1.121e-120	402.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS1_k127_6314141_6	1125863.JAFN01000001_gene2833	3.695e-93	332.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS1_k127_6314141_0	485915.Dret_1750	8.163e-226	726.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
GDHHQS1_k127_6373674_11	265072.Mfla_1753	1.867e-06	51.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,2KMPR@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS1_k127_6373674_10	861299.J421_1499	2.298e-13	79.0	COG5616@1|root,COG5616@2|Bacteria,1ZTN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_6373674_12	317936.Nos7107_3824	0.0001113	55.0	COG1462@1|root,COG1462@2|Bacteria,1G2XT@1117|Cyanobacteria,1HPMP@1161|Nostocales	1117|Cyanobacteria	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_6373674_6	1123229.AUBC01000015_gene4712	3.68e-28	131.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,3JQZ5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Probable molybdopterin binding domain	MA20_09420	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS1_k127_6373674_9	644966.Tmar_1526	1.249e-22	113.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3WDEV@538999|Clostridiales incertae sedis	186801|Clostridia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS1_k127_6373674_3	330214.NIDE0521	1.922e-44	177.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
GDHHQS1_k127_6373674_4	1303518.CCALI_01253	4.291e-38	158.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
GDHHQS1_k127_6373674_0	1128421.JAGA01000002_gene1365	3.319e-81	284.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS1_k127_6373674_8	1123511.KB905849_gene3309	8.432e-24	108.0	COG1309@1|root,COG1309@2|Bacteria,1VAVF@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137,ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_13,TetR_N
GDHHQS1_k127_6373674_5	309801.trd_A0739	9.357e-29	121.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS1_k127_6373674_2	1184267.A11Q_705	7.729e-64	227.0	COG1651@1|root,COG1651@2|Bacteria,1NZPQ@1224|Proteobacteria,42U1T@68525|delta/epsilon subdivisions,2MSXR@213481|Bdellovibrionales,2WQH9@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS1_k127_6373674_7	706587.Desti_5049	4.183e-28	124.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MS09@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS1_k127_6373674_1	243233.MCA1905	2.961e-72	256.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_646444_0	1163671.JAGI01000002_gene3528	1.65e-18	89.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,36EWX@31979|Clostridiaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS1_k127_6487609_4	292415.Tbd_0220	2.579e-111	366.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KSW1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
GDHHQS1_k127_6487609_15	1500301.JQMF01000040_gene3293	3.44e-38	154.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,4BCAY@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS1_k127_6487609_19	398527.Bphyt_5508	6.581e-21	106.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKA6@28216|Betaproteobacteria,1KFDC@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS1_k127_6487609_24	1267533.KB906733_gene3498	3.114e-09	61.0	arCOG12677@1|root,2ZCT8@2|Bacteria,3Y95Y@57723|Acidobacteria,2JNVX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6487609_27	1283300.ATXB01000001_gene1737	1.088e-05	51.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
GDHHQS1_k127_6487609_25	395965.Msil_2382	3.258e-06	58.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3NBEG@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_6487609_22	1123008.KB905694_gene1737	1.863e-15	82.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,22Y4M@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS1_k127_6487609_18	1121085.AUCI01000016_gene2110	5.474e-25	110.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS1_k127_6487609_21	536232.CLM_4131	2.979e-20	94.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS1_k127_6487609_17	1111479.AXAR01000002_gene2000	1.406e-25	116.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,27A64@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS1_k127_6487609_1	926692.AZYG01000047_gene2664	1.503e-122	409.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales	186801|Clostridia	L	Replicative DNA helicase	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS1_k127_6487609_8	485913.Krac_8380	2.598e-88	321.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_6487609_13	485915.Dret_0676	4.309e-52	206.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2M8PZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS1_k127_6487609_10	1379698.RBG1_1C00001G0979	7.089e-79	271.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS1_k127_6487609_20	1121413.JMKT01000008_gene1160	9.953e-21	106.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MC24@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS1_k127_6487609_23	404589.Anae109_1449	3.624e-15	85.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GDHHQS1_k127_6487609_2	1033734.CAET01000080_gene3305	2.183e-122	409.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
GDHHQS1_k127_6487609_11	667014.Thein_1852	1.051e-74	263.0	COG4956@1|root,COG4956@2|Bacteria,2GGWP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GDHHQS1_k127_6487609_9	589865.DaAHT2_0013	1.599e-82	291.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,2MJZP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
GDHHQS1_k127_6487609_5	264462.Bd1557	4.297e-106	364.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,Peptidase_S74
GDHHQS1_k127_6487609_14	765869.BDW_09605	2.393e-45	190.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS1_k127_6487609_0	309801.trd_1931	0.0	1309.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GDHHQS1_k127_6487609_26	338963.Pcar_0249	3.426e-06	52.0	2DGEV@1|root,2ZVPG@2|Bacteria,1QZ5A@1224|Proteobacteria,43CFW@68525|delta/epsilon subdivisions,2X7QX@28221|Deltaproteobacteria,43ST3@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6487609_6	1353529.M899_3353	3.863e-105	365.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS1_k127_6487609_3	1353529.M899_3354	5.241e-113	375.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS1_k127_6487609_7	351160.RRC456	2.453e-93	325.0	COG3263@1|root,arCOG01962@2157|Archaea	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
GDHHQS1_k127_6487609_16	795797.C497_10898	8.385e-26	123.0	COG0380@1|root,arCOG02831@2157|Archaea,2XUEY@28890|Euryarchaeota,23TNX@183963|Halobacteria	183963|Halobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
GDHHQS1_k127_6487609_12	1379698.RBG1_1C00001G0655	5.804e-69	241.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
GDHHQS1_k127_6534514_1	398767.Glov_2314	5.22e-83	303.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS1_k127_6534514_0	269799.Gmet_1853	2.383e-100	341.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43SVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GDHHQS1_k127_6534514_2	1415780.JPOG01000001_gene2846	8.001e-20	104.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1X50B@135614|Xanthomonadales	135614|Xanthomonadales	D	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS1_k127_654225_13	491916.RHECIAT_CH0002668	3.908e-14	86.0	COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria,4B79H@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS1_k127_654225_0	1123371.ATXH01000012_gene1415	1.217e-181	586.0	COG0442@1|root,COG0442@2|Bacteria,2GH47@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GDHHQS1_k127_654225_7	671143.DAMO_2467	8.657e-60	235.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
GDHHQS1_k127_654225_2	321327.CYA_0193	4.026e-101	351.0	COG0743@1|root,COG0743@2|Bacteria,1G2CU@1117|Cyanobacteria,1GYKR@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS1_k127_654225_11	515635.Dtur_1198	4.197e-36	147.0	COG4589@1|root,COG4589@2|Bacteria	2|Bacteria	S	phosphatidate cytidylyltransferase activity	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS1_k127_654225_5	1124780.ANNU01000010_gene3679	1.624e-83	297.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS1_k127_654225_6	1340493.JNIF01000003_gene4513	2.904e-83	282.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS1_k127_654225_10	1160721.RBI_II00035	8.442e-48	178.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS1_k127_654225_3	289376.THEYE_A1543	5.682e-89	299.0	COG0528@1|root,COG0528@2|Bacteria,3J0BE@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS1_k127_654225_9	649747.HMPREF0083_02756	5.131e-55	206.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,26QD1@186822|Paenibacillaceae	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS1_k127_654225_4	1000569.HMPREF1040_1280	1.145e-86	294.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS1_k127_654225_8	1173028.ANKO01000148_gene1360	2.465e-55	206.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1H8GQ@1150|Oscillatoriales	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS1_k127_654225_12	204773.HEAR0789	8.766e-15	85.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,478JS@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
GDHHQS1_k127_654225_1	204669.Acid345_3814	7.574e-179	565.0	COG1089@1|root,COG1089@2|Bacteria,3Y3QZ@57723|Acidobacteria,2JI1I@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_6562908_1	515635.Dtur_1693	2.048e-138	447.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS1_k127_6562908_5	404589.Anae109_3831	2.985e-54	203.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,42YGA@68525|delta/epsilon subdivisions,2X9TU@28221|Deltaproteobacteria,2Z21Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GDHHQS1_k127_6562908_3	693661.Arcve_0331	3.089e-89	305.0	COG4756@1|root,arCOG04052@2157|Archaea,2XWD2@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1646)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1646
GDHHQS1_k127_6562908_6	1238182.C882_0479	5.466e-27	117.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2JSJ9@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS1_k127_6562908_2	215803.DB30_5766	3.591e-92	322.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YY7A@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_6562908_4	1232410.KI421415_gene2965	3.854e-63	241.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1R5Q1@1224|Proteobacteria,42RPW@68525|delta/epsilon subdivisions,2WK10@28221|Deltaproteobacteria,43UCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_2
GDHHQS1_k127_6562908_0	1379698.RBG1_1C00001G0655	6.869e-170	550.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
GDHHQS1_k127_6614020_5	199310.c3384	9.578e-08	55.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,3XMK4@561|Escherichia	1236|Gammaproteobacteria	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltA	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	iECABU_c1320.ECABU_c30840	3D,MltA
GDHHQS1_k127_6614020_0	1089548.KI783301_gene2439	2.658e-57	212.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HD6Z@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
GDHHQS1_k127_6614020_1	318996.AXAZ01000003_gene5906	1.503e-28	123.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VEVS@28211|Alphaproteobacteria,3JSPP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	MA20_26015	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_6614020_4	404380.Gbem_1799	2.365e-12	83.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,fn3
GDHHQS1_k127_6614020_3	398578.Daci_4515	1.446e-15	94.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
GDHHQS1_k127_6614020_2	509191.AEDB02000084_gene5170	8.36e-16	95.0	COG1361@1|root,COG1470@1|root,COG2931@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,3WI1H@541000|Ruminococcaceae	186801|Clostridia	MU	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PKD,Paired_CXXCH_1,SLH,fn3
GDHHQS1_k127_6633615_2	1122951.ATUE01000005_gene2018	2.521e-18	91.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GDHHQS1_k127_6633615_3	1031288.AXAA01000015_gene341	3.124e-17	87.0	COG2119@1|root,COG2119@2|Bacteria,1VI2Y@1239|Firmicutes,24RBN@186801|Clostridia,36S12@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
GDHHQS1_k127_6633615_1	262724.TT_C0824	3.811e-23	113.0	COG1502@1|root,COG1502@2|Bacteria,1WJ7I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS1_k127_6633615_4	698737.SLGD_02420	9.517e-15	88.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,4GZK2@90964|Staphylococcaceae	91061|Bacilli	L	endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS1_k127_6633615_6	880073.Calab_2217	1.678e-08	68.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
GDHHQS1_k127_6633615_0	330214.NIDE3591	2.848e-140	475.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS1_k127_6633615_5	1459636.NTE_03342	2.075e-10	66.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6689011_15	768672.Desfe_0766	2.28e-06	51.0	COG1319@1|root,arCOG01926@2157|Archaea,2XQT2@28889|Crenarchaeota	28889|Crenarchaeota	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.5.3,1.2.99.8	ko:K03519,ko:K18021	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R10324,R11168	RC00242,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS1_k127_6689011_0	378806.STAUR_1028	1.674e-175	563.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS1_k127_6689011_11	290402.Cbei_3218	1.357e-20	100.0	COG0454@1|root,COG0456@2|Bacteria,1VI1S@1239|Firmicutes,24TT4@186801|Clostridia,36U3H@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
GDHHQS1_k127_6689011_10	1254432.SCE1572_35030	2.056e-30	131.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,42W18@68525|delta/epsilon subdivisions,2X9WW@28221|Deltaproteobacteria,2YVN9@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
GDHHQS1_k127_6689011_8	483219.LILAB_16830	3.718e-46	185.0	COG3195@1|root,COG3195@2|Bacteria,1RIGR@1224|Proteobacteria,438E6@68525|delta/epsilon subdivisions,2X3PB@28221|Deltaproteobacteria,2YWR6@29|Myxococcales	28221|Deltaproteobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
GDHHQS1_k127_6689011_3	448385.sce5877	1.234e-120	395.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
GDHHQS1_k127_6689011_1	215803.DB30_1349	5.718e-153	496.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS1_k127_6689011_14	1463934.JOCF01000105_gene6685	1.099e-06	59.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria	201174|Actinobacteria	NU	MobA-related protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS1_k127_6689011_9	215803.DB30_0217	3.002e-43	168.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria,2Z3DA@29|Myxococcales	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS1_k127_6689011_2	768706.Desor_1367	6.189e-137	456.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,26000@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	atzB	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS1_k127_6689011_13	1283287.KB822577_gene3429	3.524e-14	80.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4DRU8@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
GDHHQS1_k127_6689011_4	525904.Tter_1189	1.009e-117	390.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS1_k127_6689011_12	1121920.AUAU01000023_gene2391	1.153e-17	88.0	COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria	57723|Acidobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
GDHHQS1_k127_6689011_5	1044.EH31_10995	6.253e-103	345.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2K9GW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GDHHQS1_k127_6689011_7	1163409.UUA_00375	1.636e-64	232.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1X6FA@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
GDHHQS1_k127_6689011_6	666685.R2APBS1_2903	1.364e-86	303.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1SN7Y@1236|Gammaproteobacteria,1X4R2@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS1_k127_6702852_12	197221.22296151	3.909e-16	88.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria	1117|Cyanobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_6702852_7	861299.J421_1917	8.877e-45	178.0	COG0642@1|root,COG2205@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS1_k127_6702852_9	926554.KI912662_gene1248	9.767e-33	146.0	COG0251@1|root,COG0251@2|Bacteria,1WK0P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS1_k127_6702852_4	1265503.KB905166_gene909	9.22e-87	311.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,2Q5NM@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_ab
GDHHQS1_k127_6702852_5	269799.Gmet_0547	9.337e-74	280.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
GDHHQS1_k127_6702852_8	269799.Gmet_1425	3.463e-39	164.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,43SVG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
GDHHQS1_k127_6702852_1	398767.Glov_0469	3.307e-110	384.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
GDHHQS1_k127_6702852_6	1121423.JONT01000001_gene1927	1.609e-66	258.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,260FS@186807|Peptococcaceae	186801|Clostridia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS1_k127_6702852_2	243231.GSU2079	4.293e-104	362.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
GDHHQS1_k127_6702852_11	880072.Desac_1172	1.882e-20	103.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MQK3@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS1_k127_6702852_0	1403819.BATR01000133_gene4729	2.885e-138	447.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS1_k127_6702852_10	1123060.JONP01000014_gene4089	1.376e-28	118.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS1_k127_6702852_3	204669.Acid345_1255	1.618e-93	317.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS1_k127_6746377_11	398767.Glov_0722	5.94e-18	99.0	2DBQD@1|root,2ZADK@2|Bacteria,1NUYQ@1224|Proteobacteria,42QIK@68525|delta/epsilon subdivisions,2WK45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phytochelatin synthase	-	-	-	-	-	-	-	-	-	-	-	-	Phytochelatin
GDHHQS1_k127_6746377_0	215803.DB30_3811	0.0	1088.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2YU4U@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS1_k127_6746377_15	459349.CLOAM0344	2.232e-07	60.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
GDHHQS1_k127_6746377_13	1121346.KB899839_gene1156	2.404e-12	78.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,26R6H@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS1_k127_6746377_14	1121413.JMKT01000009_gene1972	1.053e-10	66.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2MD9B@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS1_k127_6746377_10	1307761.L21SP2_3186	1.469e-30	132.0	2C8AB@1|root,2ZW6G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6746377_9	889378.Spiaf_0742	2.325e-31	132.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GDHHQS1_k127_6746377_7	521674.Plim_4113	7.371e-96	329.0	COG0322@1|root,COG0322@2|Bacteria,2IWVR@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
GDHHQS1_k127_6746377_4	243231.GSU1493	2.688e-112	375.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS1_k127_6746377_5	706587.Desti_3123	5.598e-112	396.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_6746377_2	639282.DEFDS_1109	2.151e-166	541.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_6746377_1	1283300.ATXB01000001_gene1800	5.484e-170	550.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS1_k127_6746377_12	1307761.L21SP2_2827	4.108e-14	79.0	COG1734@1|root,COG1734@2|Bacteria,2J7Y1@203691|Spirochaetes	203691|Spirochaetes	T	Prokaryotic dksA traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
GDHHQS1_k127_6746377_3	429009.Adeg_0526	3.119e-136	455.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS1_k127_6746377_6	309801.trd_0460	1.198e-100	348.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi,27XPC@189775|Thermomicrobia	189775|Thermomicrobia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS1_k127_6746377_8	316067.Geob_3461	1.716e-55	205.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS1_k127_6761021_0	1254432.SCE1572_28455	8.562e-240	756.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS1_k127_6761021_12	574087.Acear_0218	1.219e-49	205.0	COG0457@1|root,COG2385@1|root,COG0457@2|Bacteria,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,3WABF@53433|Halanaerobiales	186801|Clostridia	D	TIGRFAM SpoIID LytB domain	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS1_k127_6761021_21	266117.Rxyl_0624	6.121e-11	75.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria	201174|Actinobacteria	G	BadF BadG BcrA BcrD	nagK	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GDHHQS1_k127_6761021_13	661478.OP10G_4092	5.676e-48	176.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
GDHHQS1_k127_6761021_1	685778.AORL01000010_gene2673	2.4e-225	736.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2KCZJ@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphoglucose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	PGI,TAL_FSA
GDHHQS1_k127_6761021_16	234267.Acid_7083	6.994e-39	169.0	COG1778@1|root,COG1778@2|Bacteria,3Y5BY@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
GDHHQS1_k127_6761021_24	935837.JAEK01000009_gene3602	5.759e-06	57.0	COG0366@1|root,COG1523@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,DUF3372,PUD,SLH
GDHHQS1_k127_6761021_9	215803.DB30_7721	5.813e-85	322.0	COG2911@1|root,COG3055@1|root,COG2911@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
GDHHQS1_k127_6761021_26	1123277.KB893244_gene5105	0.0003233	55.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
GDHHQS1_k127_6761021_18	518766.Rmar_0357	1.255e-18	98.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
GDHHQS1_k127_6761021_8	391625.PPSIR1_13615	9.264e-88	300.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_6761021_11	525903.Taci_0282	4.703e-57	226.0	COG1807@1|root,COG1807@2|Bacteria,3TAR6@508458|Synergistetes	508458|Synergistetes	M	PFAM glycosyl transferase family 39	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
GDHHQS1_k127_6761021_19	290397.Adeh_0248	7.607e-14	81.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS1_k127_6761021_17	439235.Dalk_1768	1.121e-31	135.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS1_k127_6761021_15	667014.Thein_0824	9.429e-41	166.0	COG2230@1|root,COG2230@2|Bacteria,2GID4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS1_k127_6761021_4	1297742.A176_02788	4.409e-137	442.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS1_k127_6761021_5	204669.Acid345_4707	4.546e-126	436.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria,2JKQY@204432|Acidobacteriia	204432|Acidobacteriia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
GDHHQS1_k127_6761021_25	187272.Mlg_0156	0.0002431	53.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX0E@135613|Chromatiales	135613|Chromatiales	U	PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
GDHHQS1_k127_6761021_14	309801.trd_0742	1.299e-43	183.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,27Y6N@189775|Thermomicrobia	189775|Thermomicrobia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS1_k127_6761021_20	1206741.BAFX01000017_gene7223	1.734e-12	80.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0P0@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS1_k127_6761021_2	395961.Cyan7425_1966	7.001e-161	522.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_6761021_7	1111479.AXAR01000006_gene806	4.396e-89	305.0	COG1028@1|root,COG1028@2|Bacteria,1TSWA@1239|Firmicutes,4HBHR@91061|Bacilli	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS1_k127_6761021_22	1192034.CAP_5961	2.054e-07	63.0	COG0560@1|root,COG0560@2|Bacteria,1R4DN@1224|Proteobacteria,43240@68525|delta/epsilon subdivisions,2WXVH@28221|Deltaproteobacteria,2YYEZ@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS1_k127_6761021_3	517417.Cpar_2043	5.127e-138	452.0	COG1899@1|root,COG1899@2|Bacteria,1FDI8@1090|Chlorobi	1090|Chlorobi	H	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS1_k127_6761021_10	382464.ABSI01000013_gene1636	4.711e-71	249.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS1_k127_6761021_6	1297742.A176_00097	1.173e-120	398.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS1_k127_680575_1	180281.CPCC7001_927	2.132e-60	221.0	COG1472@1|root,COG1472@2|Bacteria,1G29F@1117|Cyanobacteria,22S69@167375|Cyanobium	1117|Cyanobacteria	G	Glycosyl hydrolase family 3 N terminal domain	bgl	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Glyco_hydro_3
GDHHQS1_k127_680575_3	314345.SPV1_05258	3.948e-34	149.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria	1224|Proteobacteria	M	lytic murein transglycosylase	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
GDHHQS1_k127_680575_6	591157.SSLG_05200	9.228e-05	53.0	COG1123@1|root,COG4172@2|Bacteria,2I3AG@201174|Actinobacteria	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
GDHHQS1_k127_680575_2	309807.SRU_0527	8.631e-43	181.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1FIYA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS1_k127_680575_0	1047013.AQSP01000142_gene165	3.382e-226	721.0	COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
GDHHQS1_k127_680575_4	290317.Cpha266_2205	2.053e-22	107.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS1_k127_680575_5	1121430.JMLG01000003_gene597	6.228e-16	79.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS1_k127_6812802_2	287986.DV20_29955	6.284e-69	251.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4DXP6@85010|Pseudonocardiales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
GDHHQS1_k127_6812802_3	379066.GAU_2230	8.338e-50	185.0	COG2197@1|root,COG2197@2|Bacteria,1ZTJ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_6812802_0	1210884.HG799463_gene9317	4.865e-119	417.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_6812802_4	292459.STH2398	9.114e-50	201.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
GDHHQS1_k127_6812802_1	1121918.ARWE01000001_gene368	1.377e-69	253.0	COG0457@1|root,COG0666@1|root,COG0457@2|Bacteria,COG0666@2|Bacteria,1PGQM@1224|Proteobacteria,433NE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7047996_1	945713.IALB_2055	1.239e-26	130.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS1_k127_7047996_3	130081.XP_005705574.1	8.565e-06	61.0	COG0457@1|root,KOG0548@2759|Eukaryota	2759|Eukaryota	J	positive regulation of catalytic activity in other organism involved in symbiotic interaction	STI1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:0101031,GO:1901363	-	ko:K09553	ko05020,map05020	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_7047996_2	517418.Ctha_2595	2.541e-20	109.0	COG2304@1|root,COG2304@2|Bacteria,1FDZC@1090|Chlorobi	1090|Chlorobi	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS1_k127_7047996_0	880073.Calab_2467	4.525e-43	185.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS1_k127_7070833_3	671143.DAMO_2862	9.576e-40	153.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def2	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS1_k127_7070833_1	497964.CfE428DRAFT_0801	3.363e-103	345.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_7070833_5	497964.CfE428DRAFT_2347	4.839e-35	149.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS1_k127_7070833_6	290397.Adeh_0400	1.371e-10	74.0	COG3694@1|root,COG3694@2|Bacteria,1NAPK@1224|Proteobacteria,42X7R@68525|delta/epsilon subdivisions,2WSZA@28221|Deltaproteobacteria,2YVA3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS1_k127_7070833_0	1304275.C41B8_14525	1.315e-129	427.0	COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,1RRNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	vanA	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS1_k127_7070833_2	264732.Moth_1541	6.006e-74	267.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS1_k127_7070833_4	1336241.JAEB01000024_gene1127	5.064e-36	141.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS1_k127_7081117_31	368407.Memar_2129	1.324e-08	66.0	COG1413@1|root,arCOG06940@1|root,arCOG02966@2157|Archaea,arCOG06940@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GDHHQS1_k127_7081117_27	1439940.BAY1663_01850	1.026e-13	82.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-bound metal-dependent	XCC0762	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS1_k127_7081117_9	383372.Rcas_3420	1.095e-59	226.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
GDHHQS1_k127_7081117_4	429009.Adeg_0660	3.813e-102	367.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia,42FFF@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS1_k127_7081117_32	292459.STH595	5.968e-06	55.0	2DR9X@1|root,33AUW@2|Bacteria	2|Bacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
GDHHQS1_k127_7081117_8	1499967.BAYZ01000060_gene5985	1.495e-68	262.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,2NR14@2323|unclassified Bacteria	2|Bacteria	U	Patatin-like phospholipase	CP_0464	-	-	ko:K01999,ko:K07001	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Patatin,cNMP_binding
GDHHQS1_k127_7081117_16	264732.Moth_1504	2.687e-41	177.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS1_k127_7081117_0	1121468.AUBR01000017_gene2394	4.376e-305	973.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS1_k127_7081117_18	1485545.JQLW01000005_gene1059	1.452e-40	155.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7081117_24	981369.JQMJ01000004_gene6487	1.012e-21	99.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,2NG98@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_7081117_29	880073.Calab_2091	2.329e-11	74.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
GDHHQS1_k127_7081117_2	1123242.JH636434_gene4770	8.931e-108	359.0	COG0205@1|root,COG0205@2|Bacteria,2IYJ6@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS1_k127_7081117_33	1380355.JNIJ01000043_gene5108	9.895e-06	55.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TWQ3@28211|Alphaproteobacteria,3JU8D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1
GDHHQS1_k127_7081117_25	1125863.JAFN01000001_gene1425	7.466e-16	90.0	COG1538@1|root,COG1538@2|Bacteria,1QY91@1224|Proteobacteria,42Q4F@68525|delta/epsilon subdivisions,2WJMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_7081117_19	311424.DhcVS_266	3.774e-40	172.0	COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi,34D57@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GDHHQS1_k127_7081117_30	398767.Glov_1755	4.393e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSUQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS1_k127_7081117_12	1121406.JAEX01000005_gene3086	4.73e-53	208.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2M99K@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS1_k127_7081117_5	525897.Dbac_0647	1.238e-90	311.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2M7XK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS1_k127_7081117_1	1254432.SCE1572_14985	1.069e-145	491.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTTN@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GDHHQS1_k127_7081117_14	234267.Acid_5417	3.625e-47	188.0	COG0726@1|root,COG0726@2|Bacteria,3Y5MF@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_7081117_20	944479.JQLX01000014_gene1574	9.689e-40	154.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2M74M@213113|Desulfurellales	28221|Deltaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GDHHQS1_k127_7081117_10	1205680.CAKO01000029_gene5061	3.256e-56	206.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,2TTCH@28211|Alphaproteobacteria,2JQCT@204441|Rhodospirillales	204441|Rhodospirillales	S	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS1_k127_7081117_11	330214.NIDE1235	4.994e-55	199.0	COG0386@1|root,COG0386@2|Bacteria	2|Bacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.22,1.11.1.9	ko:K00432,ko:K20207	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	iJN678.slr1992	GSHPx
GDHHQS1_k127_7081117_23	272134.KB731324_gene1342	1.074e-23	113.0	COG1216@1|root,COG1216@2|Bacteria,1G1ZR@1117|Cyanobacteria,1H9S1@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_7081117_28	1293054.HSACCH_01258	6.747e-13	83.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,3WBMH@53433|Halanaerobiales	186801|Clostridia	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_7081117_13	1353529.M899_1416	1.538e-52	207.0	COG0463@1|root,COG0463@2|Bacteria,1Q5I6@1224|Proteobacteria,431AR@68525|delta/epsilon subdivisions,2WW8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_7081117_7	521011.Mpal_2127	4.95e-69	259.0	COG0451@1|root,arCOG04627@2157|Archaea,2XW3U@28890|Euryarchaeota,2NABN@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS1_k127_7081117_6	886293.Sinac_3912	1.008e-72	262.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_7081117_15	118173.KB235914_gene997	3.544e-42	172.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
GDHHQS1_k127_7081117_22	1121385.AQXW01000004_gene946	3.537e-26	124.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,1ZVHN@145357|Dermacoccaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS1_k127_7081117_21	103690.17131930	2.146e-37	153.0	COG1215@1|root,COG1215@2|Bacteria,1G46A@1117|Cyanobacteria,1HRM0@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_7081117_3	888060.HMPREF9081_0862	7.404e-107	361.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_7081117_17	330214.NIDE3403	3.262e-41	155.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
GDHHQS1_k127_712004_5	1191523.MROS_1568	3.113e-37	146.0	COG0509@1|root,COG0745@1|root,COG0509@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
GDHHQS1_k127_712004_2	1191523.MROS_1567	4.929e-131	428.0	COG0509@1|root,COG2204@1|root,COG0509@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GAF_2,GCV_H,Response_reg
GDHHQS1_k127_712004_1	861299.J421_3786	1.461e-157	507.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
GDHHQS1_k127_712004_7	395494.Galf_2371	2.21e-19	103.0	COG0607@1|root,COG0607@2|Bacteria,1PFQU@1224|Proteobacteria,2W38Y@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS1_k127_712004_4	290315.Clim_1429	1.009e-42	160.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
GDHHQS1_k127_712004_0	56780.SYN_01404	7.286e-168	561.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
GDHHQS1_k127_712004_3	118163.Ple7327_1594	9.278e-49	186.0	COG2203@1|root,COG3437@1|root,COG3452@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3452@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS1_k127_712004_8	575540.Isop_2854	4.091e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_712004_6	717605.Theco_2548	2.578e-26	122.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS1_k127_7125948_4	1211115.ALIQ01000237_gene2497	3.655e-18	99.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,2U0RV@28211|Alphaproteobacteria,3NCPK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_7125948_1	880072.Desac_1766	4.842e-68	253.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2MRHP@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
GDHHQS1_k127_7125948_3	215803.DB30_6050	1.161e-28	124.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2YVBP@29|Myxococcales	28221|Deltaproteobacteria	M	polysaccharide export	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS1_k127_7125948_5	1121403.AUCV01000014_gene4606	1.593e-07	63.0	COG5338@1|root,COG5338@2|Bacteria,1QTI0@1224|Proteobacteria,42PG4@68525|delta/epsilon subdivisions,2WKB2@28221|Deltaproteobacteria,2MJF0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
GDHHQS1_k127_7125948_2	696369.KI912183_gene2390	6.485e-55	201.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS1_k127_7125948_0	1340493.JNIF01000004_gene87	4.188e-120	392.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS1_k127_7140976_12	35754.JNYJ01000021_gene526	3.612e-05	56.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria,4DG4M@85008|Micromonosporales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS1_k127_7140976_3	1382306.JNIM01000001_gene876	4.927e-80	280.0	COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi	200795|Chloroflexi	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GDHHQS1_k127_7140976_8	1400525.JNIU01000001_gene314	2.855e-25	108.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,4BQ5Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GDHHQS1_k127_7140976_5	945713.IALB_1233	3.549e-67	242.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	VY92_00950	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
GDHHQS1_k127_7140976_4	525904.Tter_2147	1.442e-72	267.0	COG2377@1|root,COG2377@2|Bacteria,2NNMN@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
GDHHQS1_k127_7140976_1	1242864.D187_005156	8.294e-212	691.0	COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS1_k127_7140976_6	1121106.JQKB01000051_gene3885	4.66e-67	259.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2TWQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7140976_0	404589.Anae109_4026	0.0	3824.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS1_k127_7140976_10	1121085.AUCI01000007_gene1178	3.113e-14	79.0	29FE7@1|root,302BX@2|Bacteria,1U6E5@1239|Firmicutes,4HEFF@91061|Bacilli,1ZPE9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7140976_9	561230.PC1_0454	2.084e-15	86.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,1MRH1@122277|Pectobacterium	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS1_k127_7140976_7	365046.Rta_31020	1.036e-42	161.0	COG0784@1|root,COG0784@2|Bacteria,1QZE2@1224|Proteobacteria,2VU92@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_7140976_2	264462.Bd0695	5.138e-106	363.0	COG1502@1|root,COG1502@2|Bacteria,1Q1VG@1224|Proteobacteria,437HT@68525|delta/epsilon subdivisions,2MTHM@213481|Bdellovibrionales,2X2RB@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7206561_2	221109.22777133	3.626e-52	189.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,23KDQ@182709|Oceanobacillus	91061|Bacilli	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS1_k127_7206561_1	1184267.A11Q_2038	3.038e-101	345.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,42PTT@68525|delta/epsilon subdivisions,2MT5U@213481|Bdellovibrionales,2WS13@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Zn_pept	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
GDHHQS1_k127_7206561_0	8364.ENSXETP00000000953	2.597e-164	541.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3B98M@33208|Metazoa,3CT8Z@33213|Bilateria,47ZCM@7711|Chordata,492KW@7742|Vertebrata	33208|Metazoa	O	thimet oligopeptidase	NLN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0005886,GO:0006109,GO:0006111,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009987,GO:0010675,GO:0010830,GO:0010906,GO:0016020,GO:0016202,GO:0016787,GO:0019222,GO:0019538,GO:0031323,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033218,GO:0034641,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043603,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0048634,GO:0048641,GO:0050789,GO:0050793,GO:0050794,GO:0051147,GO:0051153,GO:0051239,GO:0062012,GO:0065007,GO:0070011,GO:0070012,GO:0070013,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1901861,GO:1902809,GO:2000026,GO:2001014	3.4.24.15,3.4.24.16	ko:K01392,ko:K01393	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS1_k127_7247188_9	1303518.CCALI_02451	3.523e-22	111.0	COG1052@1|root,COG2150@1|root,COG1052@2|Bacteria,COG2150@2|Bacteria	2|Bacteria	CH	NAD binding	serA	-	1.1.1.3,1.1.1.310,1.1.1.399,1.1.1.95,4.3.1.17	ko:K00003,ko:K00058,ko:K01752,ko:K16843	ko00260,ko00270,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020	R00220,R00590,R01513,R01773,R01775,R05693	RC00031,RC00087,RC00331,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS1_k127_7247188_3	443254.Marpi_0548	6.756e-98	331.0	COG0075@1|root,COG0075@2|Bacteria,2GCGI@200918|Thermotogae	200918|Thermotogae	E	PFAM aminotransferase class V	-	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS1_k127_7247188_0	429009.Adeg_0493	4.036e-247	793.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS1_k127_7247188_6	926560.KE387023_gene3830	2.666e-58	225.0	COG0740@1|root,COG0740@2|Bacteria,1WI6Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS1_k127_7247188_7	1125863.JAFN01000001_gene3467	1.595e-37	157.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GDHHQS1_k127_7247188_8	1392502.JNIO01000008_gene1993	3.307e-22	113.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,4H227@909932|Negativicutes	909932|Negativicutes	D	SpoIID LytB domain protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS1_k127_7247188_5	330214.NIDE3418	9.772e-73	259.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_7247188_10	1120797.KB908256_gene1996	5.634e-10	70.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,234XD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GDHHQS1_k127_7247188_4	204669.Acid345_1544	5.887e-87	307.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114	5.4.99.9	ko:K01854,ko:K21779	ko00052,ko00333,ko00520,ko01130,map00052,map00333,map00520,map01130	M00837	R00505,R09009,R11661	RC00317,RC02396	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS1_k127_7247188_1	498761.HM1_1471	3.932e-176	562.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,25F02@186801|Clostridia	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS1_k127_7247188_2	932678.THERU_02220	4.797e-104	347.0	COG0463@1|root,COG0463@2|Bacteria,2G3VF@200783|Aquificae	200783|Aquificae	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_7282256_4	1120959.ATXF01000005_gene1066	2.988e-05	55.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FN3T@85023|Microbacteriaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	paaE	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS1_k127_7282256_0	1297742.A176_03861	1.302e-100	332.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
GDHHQS1_k127_7282256_3	240292.Ava_1816	5.344e-11	72.0	COG0515@1|root,COG0515@2|Bacteria,1G28A@1117|Cyanobacteria,1HJB6@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS1_k127_7282256_1	404589.Anae109_4185	9.037e-69	246.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GDHHQS1_k127_7282256_2	525904.Tter_2279	9.194e-16	90.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
GDHHQS1_k127_7377749_15	929712.KI912613_gene3614	2.714e-32	141.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
GDHHQS1_k127_7377749_11	545695.TREAZ_2049	5.466e-48	190.0	COG1183@1|root,COG1183@2|Bacteria,2J8B5@203691|Spirochaetes	203691|Spirochaetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_7377749_13	292459.STH1715	6.706e-36	144.0	COG0688@1|root,COG0688@2|Bacteria,1V3FQ@1239|Firmicutes,24FXF@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS1_k127_7377749_8	1265313.HRUBRA_01076	1.652e-56	200.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria,1JB8J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FJ	MafB19-like deaminase	cdd	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GDHHQS1_k127_7377749_0	945713.IALB_1601	6.597e-170	550.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
GDHHQS1_k127_7377749_3	941824.TCEL_01822	2.646e-106	356.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,36DRX@31979|Clostridiaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GDHHQS1_k127_7377749_22	1120983.KB894573_gene162	3.435e-05	52.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,1JPSF@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
GDHHQS1_k127_7377749_12	1201290.M902_0988	8.336e-43	164.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,42SUC@68525|delta/epsilon subdivisions,2MTWH@213481|Bdellovibrionales,2WPR4@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GDHHQS1_k127_7377749_9	1033802.SSPSH_001785	2.156e-56	213.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	(ABC) transporter	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_7377749_5	765912.Thimo_1564	4.146e-73	280.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GDHHQS1_k127_7377749_10	292459.STH749	1.36e-55	214.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS1_k127_7377749_2	330214.NIDE0805	1.538e-129	438.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS1_k127_7377749_4	452637.Oter_1789	9.773e-83	298.0	COG2933@1|root,COG2933@2|Bacteria,46YM6@74201|Verrucomicrobia,3K7KR@414999|Opitutae	414999|Opitutae	J	FtsJ-like methyltransferase	-	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
GDHHQS1_k127_7377749_7	1121930.AQXG01000014_gene386	1.143e-58	228.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Amidinotransf,Saccharop_dh_N
GDHHQS1_k127_7377749_19	717231.Flexsi_0230	1.588e-09	70.0	COG5616@1|root,COG5616@2|Bacteria,2GEM2@200930|Deferribacteres	200930|Deferribacteres	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7377749_21	411464.DESPIG_01724	3.084e-06	59.0	COG5616@1|root,COG5616@2|Bacteria,1RBBE@1224|Proteobacteria,42QR8@68525|delta/epsilon subdivisions,2WN1X@28221|Deltaproteobacteria,2M8NQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,VCBS
GDHHQS1_k127_7377749_16	28444.JODQ01000003_gene5053	9.44e-29	119.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EIDX@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_7377749_17	1121930.AQXG01000001_gene1116	1.123e-11	77.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
GDHHQS1_k127_7377749_6	484019.THA_203	4.224e-66	249.0	COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
GDHHQS1_k127_7377749_14	765869.BDW_00945	6.039e-35	138.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2MT6Q@213481|Bdellovibrionales,2WQNR@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS1_k127_7377749_20	484019.THA_433	6.995e-08	64.0	COG0845@1|root,COG0845@2|Bacteria,2GD8D@200918|Thermotogae	200918|Thermotogae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS1_k127_7377749_1	1123368.AUIS01000032_gene1396	1.132e-140	458.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,2NBRQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS1_k127_7377749_18	264462.Bd0596	4.453e-11	72.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X75B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS1_k127_7386578_5	583355.Caka_0857	8.798e-91	317.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_7386578_6	1301098.PKB_3068	2.592e-87	309.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS1_k127_7386578_35	1298920.KI911353_gene5037	0.0008945	50.0	2EQVP@1|root,33IFG@2|Bacteria,1VQKK@1239|Firmicutes,24UY2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
GDHHQS1_k127_7386578_27	93220.LV28_20185	1.158e-13	74.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,1K9H1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS1_k127_7386578_30	882.DVU_2612	6.333e-10	65.0	2E20Q@1|root,32X8P@2|Bacteria,1NF7J@1224|Proteobacteria,42V60@68525|delta/epsilon subdivisions,2WRJ8@28221|Deltaproteobacteria,2MGN9@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7386578_24	292415.Tbd_1110	3.251e-27	124.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_17
GDHHQS1_k127_7386578_32	1125863.JAFN01000001_gene3148	2.923e-07	62.0	COG0457@1|root,COG0501@1|root,COG0457@2|Bacteria,COG0501@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
GDHHQS1_k127_7386578_9	1177179.A11A3_08465	1.939e-66	232.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Bacterioferritin	IV02_12050	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GDHHQS1_k127_7386578_31	1112214.AHIS01000014_gene119	8.848e-08	59.0	2EFZF@1|root,339RM@2|Bacteria,1Q79X@1224|Proteobacteria,2UWHC@28211|Alphaproteobacteria,2K7QX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7386578_16	1254432.SCE1572_43965	3.218e-35	150.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2YZBI@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS1_k127_7386578_25	926549.KI421517_gene3379	1.336e-22	111.0	29FE7@1|root,302BX@2|Bacteria,4NMTG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7386578_11	344747.PM8797T_04795	3.272e-61	226.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS1_k127_7386578_4	204669.Acid345_2220	3.175e-98	330.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_7386578_13	404589.Anae109_3587	9.874e-48	180.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS1_k127_7386578_20	1408444.JHYC01000005_gene841	1.174e-32	145.0	COG0671@1|root,COG0671@2|Bacteria,1RF9P@1224|Proteobacteria,1T4YU@1236|Gammaproteobacteria,1JC96@118969|Legionellales	118969|Legionellales	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS1_k127_7386578_28	1278073.MYSTI_02455	8.02e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS1_k127_7386578_15	697282.Mettu_4178	1.462e-39	155.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XFY7@135618|Methylococcales	135618|Methylococcales	S	Haemolysin-III related	-	-	-	-	-	-	-	-	-	-	-	-	HlyIII
GDHHQS1_k127_7386578_10	1267535.KB906767_gene593	3.397e-65	229.0	COG0693@1|root,COG0693@2|Bacteria,3Y4UE@57723|Acidobacteria,2JJEW@204432|Acidobacteriia	204432|Acidobacteriia	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS1_k127_7386578_19	497964.CfE428DRAFT_5269	2.972e-34	145.0	COG1363@1|root,COG1363@2|Bacteria,46T0I@74201|Verrucomicrobia	74201|Verrucomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS1_k127_7386578_21	706587.Desti_0562	3.819e-32	144.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_7386578_0	485913.Krac_3042	2.827e-208	669.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
GDHHQS1_k127_7386578_18	765869.BDW_04600	1.178e-34	134.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
GDHHQS1_k127_7386578_22	1128421.JAGA01000002_gene563	1.958e-31	130.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS1_k127_7386578_26	1144275.COCOR_07330	1.293e-20	97.0	COG0569@1|root,COG0664@1|root,COG0569@2|Bacteria,COG0664@2|Bacteria,1PDDU@1224|Proteobacteria,43EVC@68525|delta/epsilon subdivisions,2X9VE@28221|Deltaproteobacteria,2YVDM@29|Myxococcales	28221|Deltaproteobacteria	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N,cNMP_binding
GDHHQS1_k127_7386578_7	671143.DAMO_0098	1.678e-78	289.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS1_k127_7386578_14	205922.Pfl01_2176	9.545e-44	175.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T1I4@1236|Gammaproteobacteria,1YQBV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	cyaA	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
GDHHQS1_k127_7386578_12	886293.Sinac_7589	1.497e-49	192.0	COG2258@1|root,COG2258@2|Bacteria,2IZG5@203682|Planctomycetes	203682|Planctomycetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
GDHHQS1_k127_7386578_17	1280954.HPO_04960	4.569e-35	144.0	COG2267@1|root,COG2267@2|Bacteria,1R9GQ@1224|Proteobacteria,2U3YF@28211|Alphaproteobacteria,43X16@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS1_k127_7386578_2	1828.JOKB01000007_gene2585	9.656e-149	520.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4FWB2@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_7386578_1	1121346.KB899829_gene635	6.868e-158	537.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26RRK@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_7386578_33	1121033.AUCF01000005_gene5346	2.733e-06	55.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria,2JYVB@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
GDHHQS1_k127_7386578_23	1125863.JAFN01000001_gene527	5.526e-29	134.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS1_k127_7386578_8	380394.Lferr_1775	1.256e-75	264.0	COG1633@1|root,COG1633@2|Bacteria,1QG5X@1224|Proteobacteria,1RZHA@1236|Gammaproteobacteria,2NCPI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7386578_29	1463861.JNXE01000058_gene8322	1.314e-10	73.0	COG1670@1|root,COG1670@2|Bacteria,2IE9P@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS1_k127_7386578_3	330214.NIDE0014	5.392e-125	409.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS1_k127_7491012_16	767434.Fraau_2187	8.379e-11	67.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1X8A4@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
GDHHQS1_k127_7491012_6	1121445.ATUZ01000016_gene2481	1.629e-45	173.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_7491012_10	1267535.KB906767_gene4062	8.357e-33	145.0	COG3852@1|root,COG3852@2|Bacteria,3Y9A1@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS1_k127_7491012_2	1379698.RBG1_1C00001G0500	1.677e-74	267.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS1_k127_7491012_17	1220582.RRU01S_03_00410	1.169e-05	57.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,4B7PV@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
GDHHQS1_k127_7491012_12	909663.KI867150_gene2065	2.92e-27	117.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS1_k127_7491012_1	661478.OP10G_3575	8.614e-78	270.0	COG0588@1|root,COG0588@2|Bacteria	2|Bacteria	G	phosphoglycerate mutase activity	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS1_k127_7491012_14	1028801.RG1141_CH27480	5.443e-14	84.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2TTK7@28211|Alphaproteobacteria,4B8HF@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	MA20_23080	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_7491012_4	1123242.JH636435_gene1534	1.36e-56	216.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7491012_8	1283300.ATXB01000002_gene2728	1.393e-36	151.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RYYR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PocR
GDHHQS1_k127_7491012_13	317619.ANKN01000161_gene313	3.935e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1MKDA@1212|Prochloraceae	1117|Cyanobacteria	T	Alternative locus ID	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_7491012_15	1463934.JOCF01000018_gene3972	1.025e-11	77.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria	201174|Actinobacteria	O	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
GDHHQS1_k127_7491012_11	44060.JODL01000004_gene2493	4.17e-32	135.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
GDHHQS1_k127_7491012_3	264732.Moth_2027	2.303e-67	245.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GDHHQS1_k127_7491012_0	1123366.TH3_14759	4.07e-184	606.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2JQU2@204441|Rhodospirillales	204441|Rhodospirillales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS1_k127_7491012_7	1123366.TH3_14749	1.752e-45	183.0	COG0457@1|root,COG0457@2|Bacteria,1N1I4@1224|Proteobacteria,2V9ES@28211|Alphaproteobacteria,2JTPA@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
GDHHQS1_k127_7491012_9	1316936.K678_10656	2.13e-36	153.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2UFJF@28211|Alphaproteobacteria,2JZKE@204441|Rhodospirillales	204441|Rhodospirillales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS1_k127_7491012_5	234267.Acid_0104	9.918e-46	182.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_773171_1	1304874.JAFY01000005_gene1580	1.626e-166	533.0	COG1830@1|root,COG1830@2|Bacteria,3TAJ0@508458|Synergistetes	508458|Synergistetes	G	PFAM deoxyribose-phosphate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GDHHQS1_k127_773171_9	521096.Tpau_0076	6.009e-11	75.0	COG1807@1|root,COG1807@2|Bacteria,2H2FK@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_773171_3	1347369.CCAD010000011_gene2501	2.801e-42	166.0	COG1028@1|root,COG1028@2|Bacteria,1V0TV@1239|Firmicutes,4HF8Q@91061|Bacilli,1ZCCS@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS1_k127_773171_5	1123277.KB893176_gene3838	3.26e-35	145.0	COG2230@1|root,COG2230@2|Bacteria,4PNB2@976|Bacteroidetes,47RD3@768503|Cytophagia	976|Bacteroidetes	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_773171_0	589865.DaAHT2_0378	3.714e-169	540.0	COG4976@1|root,COG4976@2|Bacteria,1QW8Z@1224|Proteobacteria,43D5S@68525|delta/epsilon subdivisions,2X8CH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
GDHHQS1_k127_773171_6	589865.DaAHT2_0377	4.49e-29	132.0	COG2140@1|root,COG2140@2|Bacteria,1QZX3@1224|Proteobacteria	1224|Proteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_773171_7	765177.Desmu_0414	1.32e-21	107.0	COG0463@1|root,arCOG00894@2157|Archaea,2XPZS@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS1_k127_773171_8	401053.AciPR4_0445	3.008e-11	78.0	COG1807@1|root,COG1807@2|Bacteria,3Y46U@57723|Acidobacteria,2JIQH@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_773171_4	1121413.JMKT01000014_gene2489	2.784e-36	141.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MC2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS1_k127_773171_2	644282.Deba_2722	1.715e-65	240.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS1_k127_7755538_17	313628.LNTAR_19392	8.382e-29	118.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GDHHQS1_k127_7755538_25	1395587.P364_0113600	9.636e-10	63.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,26ZSU@186822|Paenibacillaceae	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS1_k127_7755538_23	673860.AciM339_0317	7.514e-15	82.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
GDHHQS1_k127_7755538_14	261292.Nit79A3_1589	1.307e-48	196.0	COG2211@1|root,COG2211@2|Bacteria,1NR4C@1224|Proteobacteria,2W1HW@28216|Betaproteobacteria	28216|Betaproteobacteria	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_7755538_19	755731.Clo1100_3707	1.241e-25	125.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia,36WDC@31979|Clostridiaceae	186801|Clostridia	M	NlpC/P60 family	spr	-	3.4.17.13	ko:K13694,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
GDHHQS1_k127_7755538_20	1122939.ATUD01000006_gene1643	3.309e-25	123.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_7755538_29	316067.Geob_2842	1.274e-06	62.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
GDHHQS1_k127_7755538_22	349124.Hhal_1830	5.13e-17	96.0	COG0136@1|root,335ZB@2|Bacteria,1NQEQ@1224|Proteobacteria,1SI1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
GDHHQS1_k127_7755538_15	517418.Ctha_1249	5.346e-41	172.0	COG3014@1|root,COG3014@2|Bacteria,1FFNE@1090|Chlorobi	1090|Chlorobi	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
GDHHQS1_k127_7755538_13	391615.ABSJ01000054_gene1467	8.369e-65	228.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
GDHHQS1_k127_7755538_16	330214.NIDE1646	2.06e-38	151.0	2EUFJ@1|root,33MXU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
GDHHQS1_k127_7755538_10	1537994.JQFW01000007_gene2934	1.351e-70	243.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,466JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
GDHHQS1_k127_7755538_3	671143.DAMO_1044	3.137e-106	356.0	COG0761@1|root,COG0761@2|Bacteria,2NP7K@2323|unclassified Bacteria	2|Bacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
GDHHQS1_k127_7755538_0	398767.Glov_2235	6.34e-222	704.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GDHHQS1_k127_7755538_7	1232410.KI421421_gene3667	4.549e-79	279.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43U3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS1_k127_7755538_28	765912.Thimo_3445	6.427e-07	59.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS1_k127_7755538_24	330214.NIDE2626	3.455e-10	64.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS1_k127_7755538_4	1122604.JONR01000001_gene1852	3.506e-100	344.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X790@135614|Xanthomonadales	135614|Xanthomonadales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS1_k127_7755538_2	1162668.LFE_0833	4.862e-131	455.0	COG0535@1|root,COG0535@2|Bacteria,3J0X6@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
GDHHQS1_k127_7755538_1	204669.Acid345_1740	3.401e-201	646.0	COG1657@1|root,COG1657@2|Bacteria,3Y37N@57723|Acidobacteria,2JIJP@204432|Acidobacteriia	204432|Acidobacteriia	I	Squalene-hopene cyclase C-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
GDHHQS1_k127_7755538_8	747365.Thena_0240	2.331e-78	276.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,42I94@68295|Thermoanaerobacterales	186801|Clostridia	E	COGs COG0683 ABC-type branched-chain amino acid transport systems periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS1_k127_7755538_6	1122143.AUEG01000002_gene873	1.528e-79	275.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,27FC5@186828|Carnobacteriaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS1_k127_7755538_12	795666.MW7_2552	4.48e-66	248.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1K3R4@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS1_k127_7755538_5	1121004.ATVC01000002_gene554	1.031e-80	291.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,2KQG5@206351|Neisseriales	206351|Neisseriales	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS1_k127_7755538_9	1307436.PBF_02330	2.054e-77	269.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZBFK@1386|Bacillus	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS1_k127_7755538_21	1123377.AUIV01000012_gene700	8.89e-19	87.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS1_k127_7755538_26	656519.Halsa_1406	7.327e-08	66.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,3WBMH@53433|Halanaerobiales	186801|Clostridia	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_7755538_27	649638.Trad_1334	1.098e-07	65.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_7755538_18	269799.Gmet_0975	1.028e-28	133.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS1_k127_7755538_11	671143.DAMO_3013	4.452e-69	247.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_7840108_6	655811.HMPREF0078_0983	5.375e-16	92.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,22G27@1570339|Peptoniphilaceae	186801|Clostridia	C	Six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_7840108_14	768671.ThimaDRAFT_4869	6.004e-07	63.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_7840108_5	391625.PPSIR1_42271	2.454e-16	92.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_7840108_0	1192034.CAP_2191	6.681e-82	295.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_7840108_3	755731.Clo1100_3110	4.67e-45	185.0	COG0535@1|root,COG0535@2|Bacteria,1UZPV@1239|Firmicutes,24ASI@186801|Clostridia,36NUI@31979|Clostridiaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_7840108_17	243231.GSU0884	1.813e-05	56.0	COG0641@1|root,COG0641@2|Bacteria,1R7G1@1224|Proteobacteria,42PI5@68525|delta/epsilon subdivisions,2WIK2@28221|Deltaproteobacteria,43T2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_7840108_9	1192034.CAP_3553	3.173e-11	78.0	COG0535@1|root,COG0535@2|Bacteria,1R4SH@1224|Proteobacteria,42NZR@68525|delta/epsilon subdivisions,2WKQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_7840108_13	760568.Desku_2206	2.024e-08	66.0	COG2710@1|root,COG2710@2|Bacteria,1TPJX@1239|Firmicutes,24AW6@186801|Clostridia,264RJ@186807|Peptococcaceae	186801|Clostridia	C	COG2710 Nitrogenase molybdenum-iron protein alpha and beta	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_7840108_16	641112.ACOK01000094_gene982	1.031e-06	63.0	COG2710@1|root,COG2710@2|Bacteria,1TP8Z@1239|Firmicutes,249HR@186801|Clostridia,3WHZD@541000|Ruminococcaceae	186801|Clostridia	C	Nitrogenase component 1	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_7840108_11	760568.Desku_2206	1.081e-08	68.0	COG2710@1|root,COG2710@2|Bacteria,1TPJX@1239|Firmicutes,24AW6@186801|Clostridia,264RJ@186807|Peptococcaceae	186801|Clostridia	C	COG2710 Nitrogenase molybdenum-iron protein alpha and beta	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_7840108_8	391625.PPSIR1_25656	3.552e-12	81.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2WWQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
GDHHQS1_k127_7840108_7	331678.Cphamn1_0679	7.664e-16	92.0	COG0641@1|root,COG0641@2|Bacteria,1FEDJ@1090|Chlorobi	1090|Chlorobi	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_7840108_4	237368.SCABRO_00880	4.935e-32	145.0	COG0535@1|root,COG0535@2|Bacteria,2IWZK@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_7840108_10	641112.ACOK01000094_gene982	2.562e-10	74.0	COG2710@1|root,COG2710@2|Bacteria,1TP8Z@1239|Firmicutes,249HR@186801|Clostridia,3WHZD@541000|Ruminococcaceae	186801|Clostridia	C	Nitrogenase component 1	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_7840108_2	456442.Mboo_2008	1.746e-62	226.0	COG1348@1|root,arCOG00590@2157|Archaea,2XUNI@28890|Euryarchaeota,2N9FB@224756|Methanomicrobia	224756|Methanomicrobia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	nifH-1	-	1.18.6.1,6.3.3.7	ko:K02588,ko:K21610	ko00625,ko00860,ko00910,ko01100,ko01120,map00625,map00860,map00910,map01100,map01120	M00175,M00836	R05185,R05496,R11628	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
GDHHQS1_k127_7840108_18	1150469.RSPPHO_03137	4.087e-05	57.0	COG2710@1|root,COG2710@2|Bacteria,1R3ZB@1224|Proteobacteria,2U40A@28211|Alphaproteobacteria,2JVXS@204441|Rhodospirillales	204441|Rhodospirillales	C	COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
GDHHQS1_k127_7840108_15	340177.Cag_1716	7.975e-07	62.0	COG2710@1|root,COG2710@2|Bacteria,1FDAE@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM chlorophyllide reductase subunit Z	-	-	1.3.7.14,1.3.7.15	ko:K11335	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
GDHHQS1_k127_7840108_1	1192034.CAP_3553	1.421e-79	284.0	COG0535@1|root,COG0535@2|Bacteria,1R4SH@1224|Proteobacteria,42NZR@68525|delta/epsilon subdivisions,2WKQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS1_k127_8095592_5	1521187.JPIM01000143_gene3374	1.59e-32	143.0	COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS1_k127_8095592_4	573063.Metin_0805	6.058e-34	151.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23QPZ@183939|Methanococci	183939|Methanococci	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS1_k127_8095592_1	665956.HMPREF1032_02431	6.669e-48	177.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WGN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS1_k127_8095592_2	483219.LILAB_26115	5.416e-47	178.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4
GDHHQS1_k127_8095592_0	1123242.JH636435_gene1534	3.314e-54	211.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8095592_6	1500893.JQNB01000001_gene2658	8.097e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,1QCMF@1224|Proteobacteria,1T8CR@1236|Gammaproteobacteria,1XAFR@135614|Xanthomonadales	135614|Xanthomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8095592_3	1111131.HMPREF1255_0093	3.002e-43	168.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4DN5S@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS1_k127_8132605_0	290397.Adeh_0817	1.958e-241	756.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS1_k127_8161592_1	1232410.KI421414_gene2911	5.384e-93	317.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS1_k127_8161592_0	1163409.UUA_04823	1.309e-145	473.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1X2YM@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS1_k127_8161592_4	335543.Sfum_3189	5.494e-05	51.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
GDHHQS1_k127_8161592_2	1173264.KI913949_gene937	2.336e-16	79.0	2EIWJ@1|root,33CMX@2|Bacteria,1GGWF@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8161592_3	476272.RUMHYD_02356	9.356e-08	60.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3XZV7@572511|Blautia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS1_k127_8220048_4	1123073.KB899241_gene3242	5.643e-15	89.0	COG1572@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8220048_8	1121895.Q765_16260	6.907e-07	63.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1HZFD@117743|Flavobacteriia,2NSX8@237|Flavobacterium	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
GDHHQS1_k127_8220048_2	580340.Tlie_0063	5.109e-75	272.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
GDHHQS1_k127_8220048_5	1379698.RBG1_1C00001G0757	1.16e-12	76.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
GDHHQS1_k127_8220048_6	1197906.CAJQ02000023_gene2460	2.741e-12	80.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2TUYH@28211|Alphaproteobacteria,3JSAB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8220048_1	439235.Dalk_4346	2.295e-162	520.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIA8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS1_k127_8220048_3	556268.OFAG_00881	5.555e-41	176.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,478T4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
GDHHQS1_k127_8220048_0	246197.MXAN_5402	2.667e-201	635.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria,2YXC0@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8220048_7	1231391.AMZF01000017_gene180	8.497e-11	70.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2W8VK@28216|Betaproteobacteria,3T7DI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8222361_0	562970.Btus_2136	3.321e-102	352.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,277VF@186823|Alicyclobacillaceae	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS1_k127_8222361_1	685727.REQ_42380	1.388e-80	282.0	COG1741@1|root,COG1741@2|Bacteria,2GJV3@201174|Actinobacteria,4FU43@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
GDHHQS1_k127_8222361_3	251221.35212388	5.77e-35	153.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
GDHHQS1_k127_8222361_5	1183438.GKIL_0050	2.553e-22	111.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase D Transphosphatidylase	comA	-	-	-	-	-	-	-	-	-	-	-	HHH_3,PLDc_2
GDHHQS1_k127_8222361_2	1195246.AGRI_09415	7.333e-65	232.0	COG0648@1|root,COG0648@2|Bacteria,1R6X2@1224|Proteobacteria,1RSJ8@1236|Gammaproteobacteria,465V6@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4862
GDHHQS1_k127_8222361_4	1163617.SCD_n00168	1.372e-25	110.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
GDHHQS1_k127_8222361_6	880073.Calab_1719	1.331e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS1_k127_8222361_7	1211114.ALIP01000042_gene486	7.574e-05	48.0	2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,1SGQI@1236|Gammaproteobacteria,1X92N@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
GDHHQS1_k127_8277723_0	1121920.AUAU01000019_gene2587	1.094e-67	248.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS1_k127_8277723_1	288000.BBta_7268	4.586e-67	249.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,3JTI5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	cation efflux	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS1_k127_8277723_2	1552123.EP57_15835	8.432e-42	166.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,26J72@186820|Listeriaceae	91061|Bacilli	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS1_k127_8277723_3	1218075.BAYA01000008_gene2764	1.039e-29	124.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VZEK@28216|Betaproteobacteria,1K56M@119060|Burkholderiaceae	28216|Betaproteobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
GDHHQS1_k127_8344031_3	1382304.JNIL01000001_gene3034	2.97e-115	386.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS1_k127_8344031_1	646529.Desaci_3314	6.326e-140	453.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,260WZ@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS1_k127_8344031_2	351348.Maqu_1243	6.099e-129	426.0	COG4656@1|root,COG4656@2|Bacteria,1PBU1@1224|Proteobacteria,1RP44@1236|Gammaproteobacteria,469RF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	RnfC Barrel sandwich hybrid domain	pduS	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
GDHHQS1_k127_8344031_4	234267.Acid_0708	1.069e-53	211.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GDHHQS1_k127_8344031_0	32057.KB217478_gene2230	2.979e-234	780.0	COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4
GDHHQS1_k127_8344031_5	1120746.CCNL01000010_gene1182	4.045e-37	160.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS1_k127_8344031_6	1238182.C882_4399	2.871e-24	119.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2TRH8@28211|Alphaproteobacteria,2JQ72@204441|Rhodospirillales	204441|Rhodospirillales	NT	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N
GDHHQS1_k127_8472844_1	313606.M23134_06177	5.361e-46	192.0	COG4320@1|root,COG4320@2|Bacteria,4P18K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
GDHHQS1_k127_8472844_0	497964.CfE428DRAFT_6354	1.949e-51	210.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
GDHHQS1_k127_8623565_0	1455608.JDTH01000002_gene441	7.432e-195	619.0	COG4799@1|root,arCOG02705@2157|Archaea,2XSVM@28890|Euryarchaeota,23T6H@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB2	GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885	2.1.3.15,6.4.1.2,6.4.1.3	ko:K19312	ko00280,ko00630,ko00640,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01120,map01130,map01200	M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS1_k127_8641630_21	883126.HMPREF9710_00134	7.501e-05	53.0	COG3904@1|root,COG3904@2|Bacteria,1N4W6@1224|Proteobacteria	1224|Proteobacteria	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
GDHHQS1_k127_8641630_7	1009370.ALO_02421	8.935e-98	338.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H34D@909932|Negativicutes	909932|Negativicutes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS1_k127_8641630_3	1415778.JQMM01000001_gene2044	7.677e-176	585.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1J4U2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS1_k127_8641630_16	1123371.ATXH01000011_gene65	6.14e-26	112.0	COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS1_k127_8641630_18	380358.XALC_2837	2.118e-22	112.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1X6Q2@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS1_k127_8641630_4	635013.TherJR_1781	1.324e-154	501.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
GDHHQS1_k127_8641630_14	290397.Adeh_2741	5.865e-39	164.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2YVMJ@29|Myxococcales	28221|Deltaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS1_k127_8641630_11	546274.EIKCOROL_00778	1.335e-73	273.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KPEC@206351|Neisseriales	206351|Neisseriales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS1_k127_8641630_9	1382306.JNIM01000001_gene1839	7.258e-76	280.0	COG1063@1|root,COG1063@2|Bacteria,2G6PM@200795|Chloroflexi	200795|Chloroflexi	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_8641630_13	526218.Sterm_3155	1.235e-66	240.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_8641630_19	1191523.MROS_2823	5.733e-21	106.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	-	-	-	ko:K08309,ko:K19804	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS1_k127_8641630_1	497964.CfE428DRAFT_1743	1.307e-211	676.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GDHHQS1_k127_8641630_20	426117.M446_3139	1.157e-14	83.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2UT5U@28211|Alphaproteobacteria,1JTRR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8641630_2	330214.NIDE2074	6.86e-199	623.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
GDHHQS1_k127_8641630_0	330214.NIDE2073	5.318e-270	844.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
GDHHQS1_k127_8641630_6	1121468.AUBR01000023_gene2754	4.98e-105	352.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,42GWZ@68295|Thermoanaerobacterales	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS1_k127_8641630_12	1122179.KB890414_gene1868	3.205e-69	247.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GDHHQS1_k127_8641630_15	404589.Anae109_4158	2.602e-33	144.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GDHHQS1_k127_8641630_10	500635.MITSMUL_04717	1.947e-75	266.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4H21Y@909932|Negativicutes	909932|Negativicutes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS1_k127_8641630_5	635013.TherJR_0755	6.112e-134	439.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,25ED1@186801|Clostridia,2609S@186807|Peptococcaceae	186801|Clostridia	T	PFAM PhoH-like protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
GDHHQS1_k127_8641630_17	96561.Dole_1930	1.491e-22	113.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_8641630_8	1125863.JAFN01000001_gene800	2.167e-76	261.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS1_k127_8919693_0	1333998.M2A_1693	1.246e-158	509.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,4BT82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS1_k127_8919693_1	551789.ATVJ01000004_gene406	3.723e-20	91.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,43ZE9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
GDHHQS1_k127_8982348_0	344747.PM8797T_21513	1.237e-141	466.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
GDHHQS1_k127_8982348_2	1453498.LG45_10710	3.402e-71	270.0	COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,1HZ63@117743|Flavobacteriia,2NVNY@237|Flavobacterium	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	wzxC	-	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
GDHHQS1_k127_8982348_12	706587.Desti_3022	2.98e-10	73.0	COG0438@1|root,COG0438@2|Bacteria,1PGQE@1224|Proteobacteria,43ABN@68525|delta/epsilon subdivisions,2WY7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8982348_10	562970.Btus_3249	2.58e-20	108.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,27AE4@186823|Alicyclobacillaceae	91061|Bacilli	T	low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS1_k127_8982348_4	748247.AZKH_1069	5.177e-50	196.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,2KVUX@206389|Rhodocyclales	206389|Rhodocyclales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	sthA	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GDHHQS1_k127_8982348_1	56780.SYN_02667	5.015e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2WPGD@28221|Deltaproteobacteria,2MS5H@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
GDHHQS1_k127_8982348_6	1158760.AQXP01000053_gene1488	4.993e-37	153.0	COG3919@1|root,COG3919@2|Bacteria,1N7HV@1224|Proteobacteria,1SZM6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
GDHHQS1_k127_8982348_8	316275.VSAL_I0462	2.111e-32	145.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria,1Y0UH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8982348_7	1530186.JQEY01000010_gene2782	6.647e-33	142.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2UF6H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_8982348_3	1173024.KI912149_gene5568	3.69e-58	214.0	COG1215@1|root,COG1215@2|Bacteria,1FZZM@1117|Cyanobacteria,1JK6R@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_8982348_9	373994.Riv7116_6902	1.153e-29	136.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria,1HK0T@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_8982348_13	1123487.KB892863_gene2012	2.96e-09	69.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,2VWPE@28216|Betaproteobacteria,2KZ6A@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
GDHHQS1_k127_8982348_11	643648.Slip_0013	8.247e-14	77.0	COG2402@1|root,COG2402@2|Bacteria,1VFYF@1239|Firmicutes,24RM2@186801|Clostridia	186801|Clostridia	S	contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS1_k127_9064694_2	95619.PM1_0224865	1.047e-14	86.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,1S2HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GDHHQS1_k127_9064694_0	1121346.KB899838_gene1223	2.81e-98	347.0	COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli,26SNR@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS1_k127_9064694_1	1298860.AUEM01000001_gene1742	2.906e-40	165.0	COG0329@1|root,COG0329@2|Bacteria,2GK87@201174|Actinobacteria,4FR9H@85023|Microbacteriaceae	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
GDHHQS1_k127_9068319_0	234267.Acid_0039	6.41e-153	494.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N,Response_reg
GDHHQS1_k127_9068319_1	1200792.AKYF01000012_gene1143	9.347e-29	121.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,26R27@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS1_k127_9090066_0	555079.Toce_2123	2.641e-154	497.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_9090066_3	984262.SGRA_1117	1.332e-32	145.0	COG2242@1|root,COG2242@2|Bacteria,4NYI3@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS1_k127_9090066_4	484770.UFO1_4750	1.708e-32	140.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4H4VY@909932|Negativicutes	909932|Negativicutes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS1_k127_9090066_1	1120985.AUMI01000020_gene1244	7.449e-138	448.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4H2TB@909932|Negativicutes	909932|Negativicutes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS1_k127_9090066_2	941449.dsx2_0219	4.215e-71	250.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2M7XS@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS1_k127_9101994_45	365046.Rta_29270	4.741e-05	51.0	COG3620@1|root,COG3620@2|Bacteria,1N9I8@1224|Proteobacteria,2VWM7@28216|Betaproteobacteria,4AFJH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS1_k127_9101994_15	1121920.AUAU01000023_gene2421	3.539e-70	252.0	COG0805@1|root,COG0805@2|Bacteria,3Y57K@57723|Acidobacteria	57723|Acidobacteria	U	Sec-independent protein translocase protein (TatC)	-	-	-	-	-	-	-	-	-	-	-	-	TatC
GDHHQS1_k127_9101994_34	1175306.GWL_40320	9.871e-22	106.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,474NW@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GDHHQS1_k127_9101994_24	1123354.AUDR01000015_gene235	1.563e-44	171.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,1KRNJ@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Ribonuclease HII	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS1_k127_9101994_26	1120973.AQXL01000083_gene2904	4.321e-37	144.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS1_k127_9101994_14	515635.Dtur_1534	1.412e-79	273.0	COG0336@1|root,COG0336@2|Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS1_k127_9101994_38	478749.BRYFOR_06382	2.146e-12	70.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS1_k127_9101994_37	926566.Terro_2449	5.877e-16	80.0	COG0228@1|root,COG0228@2|Bacteria,3Y56G@57723|Acidobacteria,2JJQF@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS1_k127_9101994_22	1203622.HMPREF1290_01622	1.32e-52	206.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,22KMF@1653|Corynebacteriaceae	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS1_k127_9101994_42	479431.Namu_3222	1.717e-09	69.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS1_k127_9101994_18	670487.Ocepr_2175	9.09e-65	237.0	COG0223@1|root,COG0223@2|Bacteria,1WI0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS1_k127_9101994_27	1408444.JHYC01000010_gene1535	4.262e-36	142.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1JC8J@118969|Legionellales	118969|Legionellales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS1_k127_9101994_3	234267.Acid_4619	7.024e-176	572.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS1_k127_9101994_44	1121374.KB891579_gene1756	1.009e-05	55.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
GDHHQS1_k127_9101994_33	575540.Isop_0175	2.509e-22	113.0	COG1807@1|root,COG1807@2|Bacteria,2J1QR@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9101994_32	290397.Adeh_2491	2.781e-23	109.0	COG1587@1|root,COG1587@2|Bacteria,1QYG8@1224|Proteobacteria,43CCC@68525|delta/epsilon subdivisions,2X7NB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
GDHHQS1_k127_9101994_19	1232410.KI421418_gene2108	1.31e-62	224.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS1_k127_9101994_17	292459.STH725	1.92e-65	239.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS1_k127_9101994_41	1379698.RBG1_1C00001G0331	2.882e-11	76.0	COG2067@1|root,COG2067@2|Bacteria,2NPV7@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
GDHHQS1_k127_9101994_46	1122605.KB893637_gene3372	0.0001088	53.0	COG2091@1|root,COG3321@1|root,COG2091@2|Bacteria,COG3321@2|Bacteria,4NJWH@976|Bacteroidetes,1IVQD@117747|Sphingobacteriia	976|Bacteroidetes	HQ	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,Acyl_transf_1,KAsynt_C_assoc,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
GDHHQS1_k127_9101994_2	485913.Krac_12092	6.785e-183	597.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS1_k127_9101994_23	671143.DAMO_1129	8.477e-48	180.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_9101994_1	497964.CfE428DRAFT_4597	6.165e-209	663.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
GDHHQS1_k127_9101994_36	314232.SKA53_03071	3.902e-16	91.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,2P8ZF@245186|Loktanella	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS1_k127_9101994_43	477228.YO5_13473	5.329e-06	52.0	COG1522@1|root,COG1522@2|Bacteria,1PZJA@1224|Proteobacteria,1TB8F@1236|Gammaproteobacteria,1Z4BG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS1_k127_9101994_6	566461.SSFG_02212	3.5e-127	431.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS1_k127_9101994_0	886293.Sinac_1500	1.225e-253	801.0	COG1297@1|root,COG1297@2|Bacteria,2IYGI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS1_k127_9101994_7	1219084.AP014508_gene74	3.055e-119	403.0	COG0747@1|root,COG0747@2|Bacteria,2GC5G@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS1_k127_9101994_5	374847.Kcr_1093	5.461e-135	472.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS1_k127_9101994_4	374847.Kcr_1093	2.249e-165	538.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS1_k127_9101994_9	1150474.JQJI01000048_gene1239	1.32e-101	342.0	COG0601@1|root,COG0601@2|Bacteria,2GBX3@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS1_k127_9101994_8	374847.Kcr_1095	7.574e-102	342.0	COG1173@1|root,arCOG00748@2157|Archaea	2157|Archaea	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS1_k127_9101994_11	101510.RHA1_ro04492	2.776e-88	321.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FUZV@85025|Nocardiaceae	201174|Actinobacteria	IQ	synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS1_k127_9101994_13	1128421.JAGA01000003_gene3000	9.699e-83	295.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974,ko:K07276,ko:K19545	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko01504,ko03016,ko03019	-	-	-	Aminoglyc_resit,HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GDHHQS1_k127_9101994_39	1380390.JIAT01000014_gene6288	3.619e-12	81.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
GDHHQS1_k127_9101994_35	518766.Rmar_0357	2.942e-18	102.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
GDHHQS1_k127_9101994_28	485913.Krac_11442	1.259e-34	141.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
GDHHQS1_k127_9101994_10	525909.Afer_0724	5.789e-89	320.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CMUJ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS1_k127_9101994_16	945713.IALB_1339	7.503e-68	240.0	COG0302@1|root,COG0302@2|Bacteria	2|Bacteria	H	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS1_k127_9101994_31	1131269.AQVV01000015_gene2042	6.439e-24	103.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS1_k127_9101994_29	203122.Sde_0886	2.753e-33	138.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,46AQ1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
GDHHQS1_k127_9101994_30	309801.trd_A0739	1.904e-27	119.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS1_k127_9101994_25	338969.Rfer_0415	1.019e-42	169.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
GDHHQS1_k127_9101994_20	338969.Rfer_0414	8.595e-62	222.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS1_k127_9101994_47	1121085.AUCI01000013_gene2662	0.0003947	51.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9101994_12	290397.Adeh_0391	9.429e-87	291.0	COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,42N5V@68525|delta/epsilon subdivisions,2WNIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_9108746_1	1379698.RBG1_1C00001G1089	2.157e-59	220.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_9,Response_reg
GDHHQS1_k127_9108746_0	1501230.ET33_31970	5.304e-74	267.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS1_k127_9108746_2	1123258.AQXZ01000017_gene3923	0.000182	49.0	COG0664@1|root,COG0664@2|Bacteria,2IICI@201174|Actinobacteria	201174|Actinobacteria	T	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	RHH_1,cNMP_binding
GDHHQS1_k127_9119947_1	1121296.JONJ01000019_gene102	2.898e-26	114.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,21ZM2@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GDHHQS1_k127_9119947_2	1123278.KB893602_gene1639	2.616e-11	74.0	2D6MI@1|root,32TMJ@2|Bacteria,4NPMS@976|Bacteroidetes,47Q9V@768503|Cytophagia	976|Bacteroidetes	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
GDHHQS1_k127_9119947_3	1211114.ALIP01000022_gene2437	7.627e-07	63.0	COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria,1SXRS@1236|Gammaproteobacteria,1X6NB@135614|Xanthomonadales	135614|Xanthomonadales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS1_k127_9119947_0	296591.Bpro_1663	1.495e-69	241.0	COG1917@1|root,COG1917@2|Bacteria,1MZFB@1224|Proteobacteria	1224|Proteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS1_k127_9175671_15	909663.KI867150_gene213	5.216e-27	130.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_9175671_7	1123508.JH636443_gene4834	4.725e-68	246.0	COG3832@1|root,COG3832@2|Bacteria,2J11K@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS1_k127_9175671_16	384765.SIAM614_19306	2.878e-26	113.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator, ArsR family	sdpR	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS1_k127_9175671_6	1379698.RBG1_1C00001G0675	3.992e-84	293.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
GDHHQS1_k127_9175671_14	1121861.KB899922_gene3131	1.437e-28	117.0	COG0607@1|root,COG0607@2|Bacteria,1Q2JH@1224|Proteobacteria,2UHT3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS1_k127_9175671_8	1429916.X566_21020	1.685e-64	229.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS1_k127_9175671_1	1218075.BAYA01000007_gene2641	4.008e-204	646.0	COG0531@1|root,COG0531@2|Bacteria,1MX13@1224|Proteobacteria,2VM9H@28216|Betaproteobacteria,1K3CY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS1_k127_9175671_0	272624.lpg0238	8.398e-249	775.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1JD7W@118969|Legionellales	118969|Legionellales	C	Aldehyde dehydrogenase family	gbsA	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_9175671_2	1230343.CANP01000028_gene2115	1.526e-146	478.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1JCT4@118969|Legionellales	118969|Legionellales	H	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_9175671_11	584708.Apau_0281	5.126e-57	203.0	COG0652@1|root,COG0652@2|Bacteria,3TBKH@508458|Synergistetes	508458|Synergistetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS1_k127_9175671_9	1191523.MROS_2463	3.72e-61	216.0	COG1435@1|root,COG1435@2|Bacteria	2|Bacteria	F	thymidine kinase activity	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
GDHHQS1_k127_9175671_4	368407.Memar_0186	3.803e-108	374.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_9175671_5	1232410.KI421414_gene2855	2.094e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS1_k127_9175671_17	748449.Halha_2433	3.048e-13	84.0	COG1452@1|root,COG1452@2|Bacteria,1W2IS@1239|Firmicutes	1239|Firmicutes	M	Organic solvent tolerance protein OstA	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
GDHHQS1_k127_9175671_13	110319.CF8_2732	4.722e-46	184.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4DNXD@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS1_k127_9175671_10	330214.NIDE1579	4.588e-59	231.0	COG0285@1|root,COG0285@2|Bacteria,3J0I6@40117|Nitrospirae	40117|Nitrospirae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_9175671_3	292.DM42_1398	2.068e-127	419.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,1K26U@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS1_k127_9175671_12	401526.TcarDRAFT_1423	1.878e-54	201.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4H2VA@909932|Negativicutes	909932|Negativicutes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS1_k127_918134_1	1173027.Mic7113_0581	1.447e-09	71.0	COG1922@1|root,COG1922@2|Bacteria,1G27Z@1117|Cyanobacteria,1H9YZ@1150|Oscillatoriales	1117|Cyanobacteria	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
GDHHQS1_k127_918134_0	1379270.AUXF01000004_gene3280	2.241e-51	187.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS1_k127_9191225_6	471853.Bcav_0531	7.588e-14	84.0	COG0454@1|root,COG0456@2|Bacteria,2GMPX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
GDHHQS1_k127_9191225_7	1218074.BAXZ01000022_gene4192	7.81e-13	77.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1K4TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GDHHQS1_k127_9191225_3	1499967.BAYZ01000152_gene1402	1.113e-108	370.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS1_k127_9191225_1	330214.NIDE3974	7.921e-118	401.0	COG1012@1|root,COG1012@2|Bacteria,3J0YN@40117|Nitrospirae	40117|Nitrospirae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS1_k127_9191225_4	1123376.AUIU01000011_gene1137	1.025e-33	142.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
GDHHQS1_k127_9191225_2	1121468.AUBR01000045_gene1802	6.038e-114	389.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS1_k127_9191225_5	1396.DJ87_3530	1.385e-32	141.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,1ZFPU@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS1_k127_9191225_0	1157490.EL26_09910	4.202e-136	437.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,2782U@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS1_k127_9196996_9	272557.APE_0028	0.0002516	55.0	COG0574@1|root,arCOG01114@2157|Archaea,2XS8V@28889|Crenarchaeota	28889|Crenarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
GDHHQS1_k127_9196996_2	885272.JonanDRAFT_0853	9.491e-50	203.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3TAJY@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS1_k127_9196996_4	760568.Desku_3440	1.258e-20	108.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,262N5@186807|Peptococcaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS1_k127_9196996_8	1286631.X805_23580	0.0002329	50.0	2CWJC@1|root,32SZT@2|Bacteria,1N5QU@1224|Proteobacteria,2VPCS@28216|Betaproteobacteria,1KKF9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9196996_3	497964.CfE428DRAFT_6196	1.06e-30	140.0	COG2319@1|root,COG2319@2|Bacteria,46THG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4034
GDHHQS1_k127_9196996_7	926567.TheveDRAFT_1419	0.0001061	55.0	COG1462@1|root,COG1462@2|Bacteria,3TB3V@508458|Synergistetes	508458|Synergistetes	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_9196996_6	1234364.AMSF01000090_gene2462	1.592e-10	74.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1X4W6@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
GDHHQS1_k127_9196996_5	379066.GAU_2091	9.945e-14	84.0	COG5616@1|root,COG5616@2|Bacteria,1ZTN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS1_k127_9196996_1	1121904.ARBP01000026_gene677	2.724e-53	206.0	COG4249@1|root,COG4249@2|Bacteria,4PM92@976|Bacteroidetes,47YMY@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
GDHHQS1_k127_9196996_0	1157490.EL26_01365	1.483e-96	327.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,2782J@186823|Alicyclobacillaceae	91061|Bacilli	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS1_k127_9207820_0	344747.PM8797T_05985	1.958e-75	269.0	COG2755@1|root,COG2755@2|Bacteria,2J4YR@203682|Planctomycetes	2|Bacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS1_k127_9207820_1	530564.Psta_1178	3.04e-53	207.0	COG1657@1|root,COG3345@1|root,COG1657@2|Bacteria,COG3345@2|Bacteria,2IZER@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
GDHHQS1_k127_9303675_0	365046.Rta_31990	6.674e-116	379.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS1_k127_9303675_1	1499967.BAYZ01000069_gene1845	4.619e-78	272.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS1_k127_9303675_4	880074.BARVI_00715	7.718e-13	81.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,22XR6@171551|Porphyromonadaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9303675_2	880073.Calab_2474	3.161e-61	225.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS1_k127_9303675_3	1379698.RBG1_1C00001G1774	2.755e-52	208.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS1_k127_9328115_0	1123242.JH636434_gene4957	2.291e-99	330.0	COG1216@1|root,COG1216@2|Bacteria,2IYBZ@203682|Planctomycetes	203682|Planctomycetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_9328115_1	1499967.BAYZ01000158_gene458	5.753e-26	126.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
GDHHQS1_k127_9328115_2	865861.AZSU01000002_gene2929	0.0005002	48.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,36F6R@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS1_k127_9340931_5	1123371.ATXH01000001_gene1332	1.327e-35	141.0	COG1403@1|root,COG1403@2|Bacteria,2GHGH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS1_k127_9340931_2	477974.Daud_0471	5.09e-52	199.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
GDHHQS1_k127_9340931_8	867903.ThesuDRAFT_02303	6.008e-28	124.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WCKY@538999|Clostridiales incertae sedis	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GDHHQS1_k127_9340931_10	572477.Alvin_0477	2.893e-14	80.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales	135613|Chromatiales	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GDHHQS1_k127_9340931_11	243231.GSU1757	1.514e-06	58.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,43V7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS1_k127_9340931_4	1499967.BAYZ01000195_gene3095	2.3e-39	168.0	COG0457@1|root,COG0457@2|Bacteria,2NPEN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
GDHHQS1_k127_9340931_6	1121403.AUCV01000008_gene1584	5.988e-33	149.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MJU3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS1_k127_9340931_9	1336241.JAEB01000015_gene1662	4.137e-22	98.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,25WUP@186806|Eubacteriaceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
GDHHQS1_k127_9340931_0	345219.Bcoa_1247	7.343e-132	436.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
GDHHQS1_k127_9340931_1	671143.DAMO_0507	2.965e-116	383.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
GDHHQS1_k127_9340931_7	1390370.O203_06155	5.352e-28	123.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1YE0M@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS1_k127_9340931_3	1121090.KB894705_gene1059	3.412e-41	157.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS1_k127_9343857_7	794903.OPIT5_19545	3.032e-12	71.0	COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,3K746@414999|Opitutae	414999|Opitutae	J	Met-10+ like-protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS1_k127_9343857_9	331869.BAL199_13048	8.661e-05	49.0	COG1396@1|root,COG4933@1|root,COG1396@2|Bacteria,COG4933@2|Bacteria,1N2JZ@1224|Proteobacteria,2U7T3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ASCH,HTH_3,HTH_31
GDHHQS1_k127_9343857_4	670487.Ocepr_1929	1.127e-57	209.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS1_k127_9343857_5	435591.BDI_3807	4.693e-56	204.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia,22XKJ@171551|Porphyromonadaceae	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
GDHHQS1_k127_9343857_1	880073.Calab_1713	7.719e-164	528.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,2NP9G@2323|unclassified Bacteria	2|Bacteria	S	P-loop ATPase protein family	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K06958,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03019	-	-	-	APH,ATP_bind_2
GDHHQS1_k127_9343857_8	697284.ERIC2_c31150	9.329e-07	60.0	COG4633@1|root,COG4633@2|Bacteria,1V9CQ@1239|Firmicutes,4HJCI@91061|Bacilli,26YSZ@186822|Paenibacillaceae	91061|Bacilli	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GDHHQS1_k127_9343857_2	1121920.AUAU01000020_gene2549	1.053e-115	385.0	COG0053@1|root,COG0053@2|Bacteria,3Y43E@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS1_k127_9343857_3	85643.Tmz1t_0643	3.794e-65	229.0	COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,2VYFC@28216|Betaproteobacteria,2KYSX@206389|Rhodocyclales	206389|Rhodocyclales	H	Type 12 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_9343857_6	102232.GLO73106DRAFT_00009180	8.498e-37	147.0	COG0730@1|root,COG0730@2|Bacteria,1G8K7@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS1_k127_9343857_0	234267.Acid_1818	3.357e-241	762.0	COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase M13	-	-	3.4.24.71	ko:K01415	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
GDHHQS1_k127_9354060_3	1123508.JH636439_gene1853	4.593e-69	243.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_9354060_7	1410620.SHLA_2c001640	9.533e-10	63.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,4B7RZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Cation transport ATPase	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GDHHQS1_k127_9354060_5	1162668.LFE_1618	1.715e-25	114.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	betI2	-	-	ko:K22106	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_10,TetR_N
GDHHQS1_k127_9354060_6	525373.HMPREF0766_12338	1.086e-20	100.0	2A0XU@1|root,30P2Z@2|Bacteria,4NNP7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9354060_2	686340.Metal_1980	6.232e-76	268.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1XG8M@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS1_k127_9354060_0	1121123.AUAO01000001_gene890	3.166e-96	351.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_9354060_1	264462.Bd2627	1.744e-82	284.0	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,42ZKY@68525|delta/epsilon subdivisions,2MTXG@213481|Bdellovibrionales,2WUS6@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
GDHHQS1_k127_9354060_4	448385.sce3843	5.628e-49	191.0	COG1355@1|root,COG1355@2|Bacteria,1N5H1@1224|Proteobacteria,42TIN@68525|delta/epsilon subdivisions,2WR24@28221|Deltaproteobacteria,2Z1BF@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GDHHQS1_k127_940675_5	176946.XP_007425192.1	4.054e-66	259.0	COG0439@1|root,2QRI6@2759|Eukaryota,38EE1@33154|Opisthokonta,3BFX8@33208|Metazoa,3D1XW@33213|Bilateria,489BC@7711|Chordata,4984C@7742|Vertebrata	33208|Metazoa	I	Carnosine synthase 1	CARNS1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016881,GO:0016887,GO:0017111,GO:0017144,GO:0019439,GO:0019752,GO:0034641,GO:0035498,GO:0035499,GO:0042398,GO:0043043,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0047730,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	6.3.2.11	ko:K14755	ko00330,ko00340,ko00410,map00330,map00340,map00410	-	R00910,R00912,R01164,R01991,R03286	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_4
GDHHQS1_k127_940675_14	292459.STH595	1.44e-06	57.0	2DR9X@1|root,33AUW@2|Bacteria	2|Bacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
GDHHQS1_k127_940675_13	1385519.N801_17210	8.548e-11	72.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
GDHHQS1_k127_940675_3	1123070.KB899252_gene972	1.6e-74	272.0	28NXH@1|root,2ZBV3@2|Bacteria,46TF0@74201|Verrucomicrobia,2IUAE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_940675_7	1382304.JNIL01000001_gene1912	6.589e-54	207.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,2787M@186823|Alicyclobacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
GDHHQS1_k127_940675_2	395493.BegalDRAFT_2227	2.786e-82	293.0	COG0740@1|root,COG0740@2|Bacteria	2|Bacteria	OU	serine-type endopeptidase activity	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS1_k127_940675_10	204669.Acid345_2517	2.126e-41	171.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
GDHHQS1_k127_940675_4	1122137.AQXF01000001_gene3064	6.186e-70	245.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2TSXN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	MA20_17625	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
GDHHQS1_k127_940675_12	861299.J421_4337	7.065e-12	74.0	COG2010@1|root,COG2010@2|Bacteria,1ZUYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS1_k127_940675_1	344747.PM8797T_25021	5.087e-91	306.0	COG0421@1|root,COG0421@2|Bacteria,2J4K5@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_940675_6	448385.sce2296	1.004e-61	246.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
GDHHQS1_k127_940675_11	760192.Halhy_1033	3.949e-38	162.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
GDHHQS1_k127_940675_9	469382.Hbor_12680	1.166e-44	171.0	COG0572@1|root,arCOG05133@2157|Archaea,2XU2D@28890|Euryarchaeota,23TVV@183963|Halobacteria	183963|Halobacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS1_k127_940675_8	1128421.JAGA01000002_gene480	2.389e-53	196.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS1_k127_940675_0	1449126.JQKL01000022_gene137	3.928e-141	490.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,267UY@186813|unclassified Clostridiales	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS1_k127_9563914_8	1442598.JABW01000006_gene692	3.056e-06	49.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2YSH2@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
GDHHQS1_k127_9563914_0	1210884.HG799472_gene14912	2.413e-47	173.0	COG0607@1|root,COG0607@2|Bacteria,2IZWR@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS1_k127_9563914_2	1121890.AUDO01000019_gene1054	5.328e-19	102.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia,2NUWP@237|Flavobacterium	976|Bacteroidetes	S	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS1_k127_9563914_1	889378.Spiaf_2712	6.919e-26	125.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,Response_reg,dCache_1
GDHHQS1_k127_9563914_4	1033743.CAES01000032_gene907	1.799e-16	93.0	COG0491@1|root,COG0491@2|Bacteria,1V5YS@1239|Firmicutes,4HVTY@91061|Bacilli,26V4N@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS1_k127_9563914_3	1284352.AOIG01000064_gene935	1.567e-16	81.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes,4IAYB@91061|Bacilli,273DA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9563914_7	1499689.CCNN01000005_gene344	3.431e-07	52.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,24VD5@186801|Clostridia,36W5D@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9563914_6	411467.BACCAP_03831	1.35e-14	73.0	2AEH5@1|root,314CE@2|Bacteria,1VM56@1239|Firmicutes,24XBZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9637568_6	335543.Sfum_2920	7.798e-25	121.0	COG0558@1|root,COG0558@2|Bacteria,1PDPE@1224|Proteobacteria,42XWH@68525|delta/epsilon subdivisions,2X38Z@28221|Deltaproteobacteria,2MSFQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_9637568_3	530564.Psta_1853	8.159e-75	264.0	COG5383@1|root,COG5383@2|Bacteria,2J10C@203682|Planctomycetes	203682|Planctomycetes	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
GDHHQS1_k127_9637568_4	251221.35213066	8.62e-44	173.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS1_k127_9637568_1	383372.Rcas_2645	3.622e-143	469.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
GDHHQS1_k127_9637568_0	1382356.JQMP01000004_gene488	4.339e-302	949.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS1_k127_9637568_5	383372.Rcas_1566	7.881e-30	126.0	2EB79@1|root,3357W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9637568_2	1337936.IJ00_19060	9.62e-82	279.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GDHHQS1_k127_9705609_5	1487953.JMKF01000009_gene6172	5.777e-29	118.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GDHHQS1_k127_9705609_6	314345.SPV1_10991	1.313e-18	102.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria	1224|Proteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GDHHQS1_k127_9705609_4	555079.Toce_0030	3.253e-31	130.0	COG0535@1|root,COG0535@2|Bacteria,1V3MC@1239|Firmicutes,24I1P@186801|Clostridia,42J5X@68295|Thermoanaerobacterales	186801|Clostridia	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
GDHHQS1_k127_9705609_0	1125863.JAFN01000001_gene1963	6.232e-202	655.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GDHHQS1_k127_9705609_8	768671.ThimaDRAFT_4290	0.0005438	53.0	COG4967@1|root,COG4967@2|Bacteria,1RKWI@1224|Proteobacteria,1SEEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GDHHQS1_k127_9705609_2	264732.Moth_0042	4.565e-44	168.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,42GBY@68295|Thermoanaerobacterales	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS1_k127_9705609_3	1123250.KB908394_gene1940	1.055e-34	149.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4H3FX@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GDHHQS1_k127_9705609_1	269799.Gmet_2321	1.708e-154	503.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,43T7U@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GDHHQS1_k127_9705609_7	1382359.JIAL01000001_gene1733	1.536e-18	94.0	COG0671@1|root,COG0671@2|Bacteria,3Y7BS@57723|Acidobacteria,2JKT0@204432|Acidobacteriia	204432|Acidobacteriia	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
GDHHQS1_k127_9757113_0	1210884.HG799464_gene10680	7.111e-77	265.0	COG1092@1|root,COG1092@2|Bacteria,2IYDI@203682|Planctomycetes	203682|Planctomycetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS1_k127_9796845_3	251229.Chro_5181	5.61e-85	305.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,3VMB1@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
GDHHQS1_k127_9796845_2	525904.Tter_2189	1.444e-129	458.0	COG1215@1|root,COG1215@2|Bacteria,2NPD4@2323|unclassified Bacteria	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
GDHHQS1_k127_9796845_12	379066.GAU_0986	0.0007184	52.0	COG1413@1|root,COG1413@2|Bacteria,1ZUDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS1_k127_9796845_10	1196323.ALKF01000183_gene5351	1.286e-27	116.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_9796845_5	331678.Cphamn1_2212	1.278e-71	257.0	COG3174@1|root,COG3174@2|Bacteria,1FEIM@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
GDHHQS1_k127_9796845_8	1026882.MAMP_02038	2.616e-40	151.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,460VH@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
GDHHQS1_k127_9796845_6	1437882.AZRU01000013_gene6936	3.212e-47	180.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,1S205@1236|Gammaproteobacteria,1YKJQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	OsmC-like protein	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS1_k127_9796845_9	886293.Sinac_2917	8.743e-34	133.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS1_k127_9796845_0	1266925.JHVX01000006_gene2103	2.813e-135	454.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,2VK4G@28216|Betaproteobacteria,37273@32003|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS1_k127_9796845_7	234267.Acid_3599	3.158e-43	179.0	COG1225@1|root,COG1225@2|Bacteria,3Y4W0@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS1_k127_9796845_4	1201290.M902_3130	5.278e-77	272.0	COG0501@1|root,COG0501@2|Bacteria,1NF76@1224|Proteobacteria,42WFB@68525|delta/epsilon subdivisions,2MTHK@213481|Bdellovibrionales,2WSAI@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS1_k127_9796845_11	396588.Tgr7_0172	1.626e-26	110.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS1_k127_9796845_1	1254432.SCE1572_24875	4.198e-131	424.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YWWY@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS1_k127_9811466_2	319795.Dgeo_1883	1.172e-64	240.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	phaA	GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS1_k127_9811466_3	1340493.JNIF01000003_gene2631	9.321e-59	221.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfbU	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_9811466_5	1307436.PBF_21068	1.328e-23	109.0	COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli,1ZI8A@1386|Bacillus	91061|Bacilli	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS1_k127_9811466_4	324602.Caur_0726	3.077e-25	116.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GDHHQS1_k127_9811466_0	483219.LILAB_14510	1.208e-141	460.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUBG@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS1_k127_9811466_6	864073.HFRIS_005338	0.0002493	52.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_9811466_1	344747.PM8797T_16917	7.002e-80	286.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
GDHHQS1_k127_985937_9	349521.HCH_03685	3.985e-49	183.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RMJR@1236|Gammaproteobacteria,1XIS8@135619|Oceanospirillales	135619|Oceanospirillales	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS1_k127_985937_1	644966.Tmar_1672	6.475e-124	408.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia	186801|Clostridia	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS1_k127_985937_5	243231.GSU2654	5.102e-95	323.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,43UJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS1_k127_985937_6	6500.XP_005093392.1	2.826e-91	323.0	COG0320@1|root,KOG2672@2759|Eukaryota,38EBV@33154|Opisthokonta,3BEE6@33208|Metazoa,3CRPM@33213|Bilateria	33208|Metazoa	H	GO:0070283	LIAS	GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002237,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009987,GO:0010033,GO:0010467,GO:0014020,GO:0016053,GO:0016331,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0021915,GO:0031974,GO:0032496,GO:0032501,GO:0032502,GO:0032787,GO:0033993,GO:0034641,GO:0035148,GO:0035239,GO:0035295,GO:0036211,GO:0042221,GO:0043009,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0048598,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0051604,GO:0051704,GO:0051707,GO:0060429,GO:0060562,GO:0060606,GO:0070013,GO:0070283,GO:0071704,GO:0072175,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901700	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS1_k127_985937_3	266117.Rxyl_0229	6.165e-109	364.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS1_k127_985937_19	876044.IMCC3088_776	3.116e-06	54.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808	FolB
GDHHQS1_k127_985937_7	857571.EA1_04445	1.273e-77	265.0	COG0720@1|root,COG0720@2|Bacteria,1R62M@1224|Proteobacteria,1RYDG@1236|Gammaproteobacteria,3NIPN@468|Moraxellaceae	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS1_k127_985937_8	861299.J421_3591	3.151e-50	200.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS1_k127_985937_18	1286631.X805_15610	2.878e-09	71.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria,1KKFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Single cache domain 3	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
GDHHQS1_k127_985937_13	1449080.JQMV01000003_gene1031	2.544e-32	147.0	COG5002@1|root,COG5002@2|Bacteria,1WIY6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS1_k127_985937_12	682795.AciX8_0031	5.192e-33	143.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria,2JJH8@204432|Acidobacteriia	204432|Acidobacteriia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS1_k127_985937_15	1340493.JNIF01000003_gene3303	2.481e-22	109.0	COG1018@1|root,COG1018@2|Bacteria,3Y4SB@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS1_k127_985937_14	869210.Marky_1021	2.25e-24	119.0	COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS1_k127_985937_2	751945.Theos_0004	3.095e-113	382.0	COG0469@1|root,COG0469@2|Bacteria,1WJAC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS1_k127_985937_4	1304880.JAGB01000001_gene848	2.891e-96	326.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GDHHQS1_k127_985937_17	497964.CfE428DRAFT_3040	5.638e-11	73.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS1_k127_985937_10	648996.Theam_1066	4.982e-47	177.0	COG0325@1|root,COG0325@2|Bacteria,2G3XD@200783|Aquificae	200783|Aquificae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS1_k127_985937_16	227377.CBU_0943	7.577e-17	89.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese,SNARE_assoc
GDHHQS1_k127_985937_0	748727.CLJU_c37190	1.762e-211	669.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,36E1F@31979|Clostridiaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS1_k127_985937_11	1499967.BAYZ01000009_gene5396	7.308e-36	139.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS1_k127_9993376_18	592028.GCWU000321_00522	3.448e-05	57.0	COG3409@1|root,COG3584@1|root,COG3409@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4H4W0@909932|Negativicutes	909932|Negativicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,PG_binding_1
GDHHQS1_k127_9993376_15	1157634.KB913010_gene769	2.613e-12	80.0	COG3409@1|root,COG3409@2|Bacteria,2GMGY@201174|Actinobacteria	201174|Actinobacteria	M	Fungal chitosanase of glycosyl hydrolase group 75	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_75
GDHHQS1_k127_9993376_9	1038862.KB893840_gene945	8.238e-66	233.0	COG4894@1|root,COG4894@2|Bacteria,1RFQF@1224|Proteobacteria,2URA1@28211|Alphaproteobacteria,3K3U8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
GDHHQS1_k127_9993376_16	1121898.Q766_05100	5.317e-12	68.0	2EKBF@1|root,33E1U@2|Bacteria,4NXYA@976|Bacteroidetes,1IDB5@117743|Flavobacteriia,2NXXH@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_5	264462.Bd1198	2.917e-96	328.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2MTNC@213481|Bdellovibrionales,2WJ0A@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS1_k127_9993376_6	626887.J057_15935	3.795e-90	317.0	COG5298@1|root,COG5298@2|Bacteria,1MYMJ@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
GDHHQS1_k127_9993376_14	1040986.ATYO01000003_gene5858	7.92e-15	74.0	2E328@1|root,32Y2G@2|Bacteria,1N9RI@1224|Proteobacteria,2UFJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_2	880072.Desac_2171	1.078e-141	477.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
GDHHQS1_k127_9993376_17	1123325.JHUV01000013_gene1624	1.197e-11	68.0	arCOG07300@1|root,2ZTGG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_10	1173026.Glo7428_0554	9.563e-28	120.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS1_k127_9993376_8	627192.SLG_11520	3.405e-68	237.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_4	448385.sce1586	7.224e-103	342.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_12	1535422.ND16A_0698	4.7e-16	85.0	COG0457@1|root,COG0457@2|Bacteria,1RESK@1224|Proteobacteria,1S41N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_9993376_0	314230.DSM3645_08071	3.177e-184	586.0	COG0372@1|root,COG0372@2|Bacteria,2IYFN@203682|Planctomycetes	203682|Planctomycetes	H	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS1_k127_9993376_13	404380.Gbem_1086	2.413e-15	86.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GDHHQS1_k127_9993376_11	706587.Desti_4133	1.163e-20	103.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9993376_3	583355.Caka_0067	3.117e-116	391.0	COG0437@1|root,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
GDHHQS1_k127_9993376_1	448385.sce4706	2.979e-156	503.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS1_k127_9993376_7	1121413.JMKT01000008_gene1013	3.861e-78	285.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
## 2604 queries scanned
## Total time (seconds): 88.91616678237915
## Rate: 29.29 q/s