## Wed Nov 13 03:04:41 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/G/GDHHQS1_bin.85.fa -m mmseqs --itype genome -o GDHHQS1_bin.85 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/GDHHQS1_bin.85 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS1_k127_10003507_1	1396141.BATP01000027_gene1160	3.804e-32	146.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_10003507_2	641112.ACOK01000086_gene3447	2.946e-11	78.0	COG3866@1|root,COG4677@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,1TSCD@1239|Firmicutes,24AHP@186801|Clostridia,3WHG8@541000|Ruminococcaceae	186801|Clostridia	G	Pectinesterase	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
GDHHQS1_k127_10003507_0	237368.SCABRO_00637	3.529e-103	341.0	COG3228@1|root,COG3228@2|Bacteria,2IZES@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
GDHHQS1_k127_1000958_1	1249997.JHZW01000002_gene1755	2.204e-32	139.0	COG0388@1|root,COG0388@2|Bacteria,4PE65@976|Bacteroidetes,1IENF@117743|Flavobacteriia,2PIBH@252356|Maribacter	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS1_k127_1000958_0	452637.Oter_1311	7.772e-77	267.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1000958_2	1254432.SCE1572_07780	9.652e-13	72.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GDHHQS1_k127_10013540_0	247490.KSU1_D0406	3.037e-120	402.0	COG0773@1|root,COG0773@2|Bacteria,2IYEH@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_10013540_2	595460.RRSWK_04062	1.179e-19	91.0	COG1551@1|root,COG1551@2|Bacteria,2J0YE@203682|Planctomycetes	203682|Planctomycetes	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
GDHHQS1_k127_10013540_1	382464.ABSI01000009_gene3921	3.195e-66	231.0	COG1502@1|root,COG1502@2|Bacteria,46X9U@74201|Verrucomicrobia,2IUGR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS1_k127_10013540_3	105559.Nwat_1924	9.485e-18	82.0	COG1724@1|root,COG1724@2|Bacteria,1NHPS@1224|Proteobacteria,1SGDT@1236|Gammaproteobacteria,1WZRG@135613|Chromatiales	135613|Chromatiales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
GDHHQS1_k127_10029829_2	697281.Mahau_2778	0.0002559	46.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,42EVB@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS1_k127_10029829_1	1142394.PSMK_13590	6.365e-33	133.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
GDHHQS1_k127_10029829_0	269799.Gmet_3159	1.17e-222	708.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43T5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS1_k127_10041756_0	1120963.KB894500_gene100	2.48e-238	750.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS1_k127_10041756_2	1191523.MROS_2759	8.247e-56	200.0	COG0503@1|root,COG0503@2|Bacteria	2|Bacteria	F	purine ribonucleoside salvage	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
GDHHQS1_k127_10041756_1	243090.RB3727	1.907e-67	238.0	COG0568@1|root,COG0568@2|Bacteria,2IYCB@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_1004580_1	1168034.FH5T_07240	1.019e-09	72.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3
GDHHQS1_k127_1004580_0	880070.Cycma_0727	2.127e-26	127.0	COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia	976|Bacteroidetes	S	Kelch repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_4,Kelch_6,Malectin,PKD
GDHHQS1_k127_10068323_0	390874.Tpet_0358	2.482e-310	960.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2GBZA@200918|Thermotogae	200918|Thermotogae	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
GDHHQS1_k127_10068323_1	1123405.AUMM01000002_gene327	6.195e-82	280.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26NJH@186821|Sporolactobacillaceae	91061|Bacilli	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS1_k127_10068323_2	936140.AEOT01000015_gene1492	3.285e-20	97.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS1_k127_10105943_4	240015.ACP_0965	8.996e-26	110.0	COG0745@1|root,COG0745@2|Bacteria,3Y53N@57723|Acidobacteria,2JN7U@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS1_k127_10105943_6	398767.Glov_3310	2.552e-10	69.0	COG1406@1|root,COG1406@2|Bacteria,1N38Q@1224|Proteobacteria,42UIA@68525|delta/epsilon subdivisions,2WQV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	cheX64H	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
GDHHQS1_k127_10105943_8	197221.22294240	4.872e-06	59.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1FZVS@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
GDHHQS1_k127_10105943_0	379066.GAU_0360	3.022e-152	508.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1ZTCI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
GDHHQS1_k127_10105943_2	1304885.AUEY01000002_gene425	2.594e-85	291.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2MJG1@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
GDHHQS1_k127_10105943_3	234267.Acid_5371	6.28e-43	162.0	COG1871@1|root,COG1871@2|Bacteria,3Y5E5@57723|Acidobacteria	57723|Acidobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
GDHHQS1_k127_10105943_5	56780.SYN_00967	1.641e-25	111.0	COG2204@1|root,COG2204@2|Bacteria,1READ@1224|Proteobacteria,42RG0@68525|delta/epsilon subdivisions,2WNUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS1_k127_10105943_9	861299.J421_0155	0.0001799	49.0	COG1406@1|root,COG1406@2|Bacteria,1ZU7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
GDHHQS1_k127_10105943_7	485915.Dret_0656	2.459e-08	60.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MET3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
GDHHQS1_k127_10105943_1	439235.Dalk_0655	1.679e-94	316.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,2MHVY@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS1_k127_10117396_0	671143.DAMO_1461	1.681e-119	396.0	COG2377@1|root,COG2377@2|Bacteria,2NNMN@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
GDHHQS1_k127_10117396_1	237368.SCABRO_03990	5.058e-97	326.0	COG2103@1|root,COG2103@2|Bacteria,2IWTZ@203682|Planctomycetes	203682|Planctomycetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
GDHHQS1_k127_10117396_2	583355.Caka_0857	7.256e-83	293.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_10122658_1	56780.SYN_02383	1.081e-161	517.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MR7X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
GDHHQS1_k127_10122658_2	1232410.KI421412_gene16	8.401e-76	259.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,43SUV@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
GDHHQS1_k127_10122658_0	406327.Mevan_1556	2.304e-231	721.0	COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS1_k127_10162157_0	452637.Oter_2196	4.321e-121	396.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_10162157_1	706587.Desti_1020	1.24e-70	251.0	COG2519@1|root,COG2519@2|Bacteria,1QTU3@1224|Proteobacteria,43CWX@68525|delta/epsilon subdivisions,2X84W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS1_k127_10207083_0	1121904.ARBP01000008_gene3234	2.562e-209	669.0	COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,47TBW@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
GDHHQS1_k127_10207083_1	1487921.DP68_11465	1.56e-16	88.0	COG1595@1|root,COG1595@2|Bacteria,1V3PA@1239|Firmicutes,24HAV@186801|Clostridia,36K2Q@31979|Clostridiaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_10249961_2	218284.CCDN010000007_gene3799	4.044e-10	68.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus	91061|Bacilli	D	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS1_k127_10249961_1	289376.THEYE_A0518	8.539e-162	515.0	COG0863@1|root,COG1525@1|root,COG0863@2|Bacteria,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	2.1.1.113,3.1.31.1	ko:K00590,ko:K01174,ko:K02027	-	M00207	-	-	ko00000,ko00002,ko01000,ko02000,ko02048	3.A.1.1	-	-	Excalibur,N6_N4_Mtase,SNase
GDHHQS1_k127_10249961_0	1125863.JAFN01000001_gene2870	2.318e-217	690.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS1_k127_1025862_2	1267534.KB906755_gene4826	1.565e-13	72.0	COG1181@1|root,COG1181@2|Bacteria,3Y6Z0@57723|Acidobacteria,2JKPX@204432|Acidobacteriia	204432|Acidobacteriia	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS1_k127_1025862_1	316274.Haur_0889	3.03e-44	184.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF5060
GDHHQS1_k127_1025862_0	96561.Dole_2351	1.346e-123	400.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MIFH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS1_k127_10270333_1	373903.Hore_02560	1.198e-15	78.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WBQF@53433|Halanaerobiales	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	macB_8	-	-	ko:K02004,ko:K16918	ko02010,map02010	M00258,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_10270333_0	1236959.BAMT01000001_gene1729	1.762e-85	305.0	COG1538@1|root,COG1538@2|Bacteria,1NEHN@1224|Proteobacteria,2VYWE@28216|Betaproteobacteria,2KKVJ@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_10317152_2	344747.PM8797T_14229	5.996e-16	84.0	COG2980@1|root,COG2980@2|Bacteria,2J05A@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
GDHHQS1_k127_10317152_0	1142394.PSMK_25340	1.458e-205	659.0	COG0465@1|root,COG0465@2|Bacteria,2IWU2@203682|Planctomycetes	203682|Planctomycetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS1_k127_10317152_1	880073.Calab_3562	1.714e-56	217.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,2NPKJ@2323|unclassified Bacteria	2|Bacteria	CO	Protein of unknown function, DUF255	dsbD	-	1.8.1.8	ko:K04084,ko:K06888	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS1_k127_10330633_0	237368.SCABRO_03442	3.844e-277	871.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
GDHHQS1_k127_10330633_2	1123508.JH636441_gene3359	1.253e-50	191.0	COG0287@1|root,COG0287@2|Bacteria,2IZ5K@203682|Planctomycetes	203682|Planctomycetes	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GDHHQS1_k127_10330633_1	530564.Psta_4222	9.105e-111	370.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
GDHHQS1_k127_10330633_3	314230.DSM3645_08612	1.712e-07	53.0	COG0698@1|root,COG0698@2|Bacteria,2IZKI@203682|Planctomycetes	203682|Planctomycetes	G	COG0698 Ribose 5-phosphate isomerase RpiB	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS1_k127_1034331_0	55529.EKX33182	3.751e-05	56.0	2DZR0@1|root,2S77T@2759|Eukaryota	2759|Eukaryota	S	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,PA14,SRCR
GDHHQS1_k127_10349465_1	1472716.KBK24_0121530	3.051e-21	109.0	COG1475@1|root,COG1475@2|Bacteria,1RBCD@1224|Proteobacteria,2VQCK@28216|Betaproteobacteria,1K6RM@119060|Burkholderiaceae	28216|Betaproteobacteria	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
GDHHQS1_k127_10349465_0	479431.Namu_2715	1.013e-39	155.0	COG2214@1|root,COG2214@2|Bacteria,2GQTA@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1036378_0	1123508.JH636449_gene7410	2.042e-20	105.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999,LptC,NLPC_P60,SH3_3
GDHHQS1_k127_1036378_2	1380391.JIAS01000017_gene440	8.884e-07	62.0	COG0810@1|root,COG5373@1|root,COG0810@2|Bacteria,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2TWNB@28211|Alphaproteobacteria,2JSRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS1_k127_1036378_1	543728.Vapar_1537	7.952e-17	94.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria,4AGCU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS1_k127_10415578_1	794903.OPIT5_29015	1.929e-10	71.0	COG2165@1|root,COG2165@2|Bacteria,46Y3R@74201|Verrucomicrobia,3K99Z@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_10415578_0	595460.RRSWK_00887	4.778e-28	117.0	COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
GDHHQS1_k127_10438165_0	1282887.AUJG01000001_gene1823	2.131e-57	207.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS1_k127_10438165_1	546275.FUSPEROL_00340	3.966e-06	57.0	COG1132@1|root,COG1132@2|Bacteria,378QA@32066|Fusobacteria	32066|Fusobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS1_k127_10478503_2	290397.Adeh_2216	2.337e-30	127.0	2DBW6@1|root,2ZBEP@2|Bacteria,1QUH5@1224|Proteobacteria,43CCA@68525|delta/epsilon subdivisions,2X7N7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM decaheme c-type cytochrome, OmcA MtrC family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10478503_1	935863.AWZR01000007_gene307	3.092e-37	158.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1X3HB@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS1_k127_10478503_0	886293.Sinac_2390	5.337e-184	587.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_10482041_1	1142394.PSMK_17540	1.378e-93	327.0	COG1480@1|root,COG1480@2|Bacteria,2IYP7@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
GDHHQS1_k127_10482041_2	1142394.PSMK_17530	2.066e-93	316.0	COG1702@1|root,COG1702@2|Bacteria,2IXBB@203682|Planctomycetes	203682|Planctomycetes	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS1_k127_10482041_6	1210884.HG799469_gene14232	2.682e-34	142.0	COG4589@1|root,COG4589@2|Bacteria,2J032@203682|Planctomycetes	203682|Planctomycetes	S	Phosphatidate cytidylyltransferase	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS1_k127_10482041_3	314230.DSM3645_07730	8.997e-76	262.0	COG0020@1|root,COG0020@2|Bacteria,2IX6Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS1_k127_10482041_0	2325.TKV_c24210	1.396e-142	464.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,42FKX@68295|Thermoanaerobacterales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS1_k127_10482041_4	886293.Sinac_3598	2.943e-60	219.0	2CB5F@1|root,2ZCDM@2|Bacteria,2IXTM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10482041_5	1246448.ANAZ01000015_gene6059	7.06e-40	164.0	COG1968@1|root,COG1968@2|Bacteria,2H2JC@201174|Actinobacteria	201174|Actinobacteria	V	Bacitracin resistance protein BacA	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS1_k127_10482041_7	909943.HIMB100_00001780	3.681e-15	88.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2UGK6@28211|Alphaproteobacteria,4BR4X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
GDHHQS1_k127_10513982_2	443144.GM21_1696	3.99e-22	105.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS1_k127_10513982_3	882.DVU_1534	3.053e-08	63.0	COG2391@1|root,COG2391@2|Bacteria,1RDQK@1224|Proteobacteria,42RU6@68525|delta/epsilon subdivisions,2WNJT@28221|Deltaproteobacteria,2MBSU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS1_k127_10513982_0	1403819.BATR01000092_gene2658	3.137e-193	614.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_10513982_1	1288963.ADIS_1243	4.823e-61	220.0	COG3119@1|root,COG3119@2|Bacteria,4NE7S@976|Bacteroidetes	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_10554389_3	1168034.FH5T_18780	6.682e-37	142.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
GDHHQS1_k127_10554389_0	1415778.JQMM01000001_gene314	2.368e-64	232.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1J5AK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0657 Esterase lipase	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
GDHHQS1_k127_10554389_4	345341.KUTG_02223	1.382e-12	78.0	COG1409@1|root,COG1409@2|Bacteria,2IAPW@201174|Actinobacteria,4E8FP@85010|Pseudonocardiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ_2
GDHHQS1_k127_10554389_1	573413.Spirs_1747	9.886e-59	217.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
GDHHQS1_k127_10554389_2	97139.C824_01928	1.005e-55	202.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_10597696_0	1121405.dsmv_3372	4.827e-73	254.0	COG1141@1|root,COG2878@1|root,COG1141@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42PTG@68525|delta/epsilon subdivisions,2WKYG@28221|Deltaproteobacteria,2MIM0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
GDHHQS1_k127_10597696_2	1499967.BAYZ01000102_gene3568	1.1e-55	200.0	COG4657@1|root,COG4657@2|Bacteria,2NPB0@2323|unclassified Bacteria	2|Bacteria	U	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
GDHHQS1_k127_10597696_1	879212.DespoDRAFT_02017	4.609e-62	219.0	COG4660@1|root,COG4660@2|Bacteria,1R4EB@1224|Proteobacteria,42PW0@68525|delta/epsilon subdivisions,2WKTN@28221|Deltaproteobacteria,2MJEI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NqrDE RnfAE family	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
GDHHQS1_k127_10597696_3	1321784.HMPREF1987_02220	7.293e-11	70.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
GDHHQS1_k127_10604410_0	1226325.HMPREF1548_05084	2.075e-155	504.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,36H2N@31979|Clostridiaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS1_k127_10604410_1	1499967.BAYZ01000171_gene5529	8.32e-59	209.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS1_k127_10604410_4	1121285.AUFK01000009_gene1148	4.557e-11	78.0	COG4733@1|root,COG4733@2|Bacteria,4PKYK@976|Bacteroidetes,1IJHK@117743|Flavobacteriia,3ZQWF@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Pec_lyase_C,fn3
GDHHQS1_k127_10604410_3	717606.PaecuDRAFT_2334	5.055e-34	153.0	COG1404@1|root,COG2133@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78,3.4.21.62,3.4.21.66	ko:K01206,ko:K01218,ko:K01342,ko:K08651,ko:K14645	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Glyco_hydro_26,PA14,PKD,PPC,Peptidase_S8
GDHHQS1_k127_10604410_2	247490.KSU1_D0514	3.358e-50	207.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
GDHHQS1_k127_10612074_1	1173027.Mic7113_4331	4.179e-63	219.0	COG0436@1|root,COG0436@2|Bacteria,1G24E@1117|Cyanobacteria,1H6X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS1_k127_10612074_0	1499967.BAYZ01000166_gene6617	1.842e-250	779.0	COG0362@1|root,COG0362@2|Bacteria,2NS40@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS1_k127_1064821_3	1380346.JNIH01000038_gene3863	4.607e-06	55.0	2B7DF@1|root,320H0@2|Bacteria,2H46K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1064821_0	330214.NIDE1067	6.36e-189	615.0	2DBJW@1|root,2Z9P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1064821_2	247490.KSU1_D0273	7.001e-121	400.0	COG0535@1|root,COG0535@2|Bacteria,2J1NE@203682|Planctomycetes	203682|Planctomycetes	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
GDHHQS1_k127_1064821_1	1168034.FH5T_18125	7.476e-130	426.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_10658590_2	1121472.AQWN01000001_gene100	5.791e-23	99.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,262RP@186807|Peptococcaceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
GDHHQS1_k127_10658590_0	1408473.JHXO01000008_gene2652	1.67e-191	603.0	COG0438@1|root,COG0438@2|Bacteria,4NKIM@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS1_k127_10658590_1	1499967.BAYZ01000038_gene2268	9.482e-170	542.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,GDE_C,Glyco_hydro_100,S6PP
GDHHQS1_k127_10743008_0	1142394.PSMK_27340	2.16e-57	212.0	COG2208@1|root,COG4936@1|root,COG2208@2|Bacteria,COG4936@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
GDHHQS1_k127_10743008_1	1051632.TPY_1556	3.764e-51	189.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WCJJ@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS1_k127_10743008_2	1142394.PSMK_07740	1.056e-37	156.0	COG0204@1|root,COG0204@2|Bacteria,2IZVC@203682|Planctomycetes	203682|Planctomycetes	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS1_k127_10743008_3	1123508.JH636450_gene7185	1.174e-16	83.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_10746121_0	215803.DB30_4063	3.352e-194	612.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS1_k127_10746121_1	278963.ATWD01000001_gene3347	5.11e-173	552.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
GDHHQS1_k127_10746121_2	1123242.JH636435_gene2208	5.555e-116	384.0	COG4299@1|root,COG4299@2|Bacteria,2J1X5@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10746121_3	1123277.KB893180_gene2412	6.207e-77	262.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,47MDE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
GDHHQS1_k127_1078952_3	1461693.ATO10_10605	7.683e-05	53.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,2TTKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	trgB	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	GGACT,NUDIX
GDHHQS1_k127_1078952_1	370438.PTH_1466	4.8e-82	281.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,267CB@186807|Peptococcaceae	186801|Clostridia	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_1078952_0	28072.Nos7524_4807	1.12e-125	411.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1HIFU@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_10873838_0	313628.LNTAR_00920	1.888e-129	433.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
GDHHQS1_k127_10873838_1	666509.RCA23_c06530	1.44e-17	87.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2U33R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_10876158_4	323259.Mhun_1680	5.495e-05	48.0	COG2250@1|root,arCOG01191@2157|Archaea	2157|Archaea	F	PFAM HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_10876158_5	1499967.BAYZ01000123_gene2516	0.0001225	49.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS1_k127_10876158_2	864702.OsccyDRAFT_2874	4.129e-31	128.0	COG2250@1|root,COG2250@2|Bacteria,1GAHS@1117|Cyanobacteria,1HGDK@1150|Oscillatoriales	1117|Cyanobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_10876158_0	3694.POPTR_0010s24550.1	2.936e-150	485.0	COG0137@1|root,KOG1706@2759|Eukaryota,37QUX@33090|Viridiplantae,3G8Y6@35493|Streptophyta,4JEKX@91835|fabids	35493|Streptophyta	E	Argininosuccinate synthase	-	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS1_k127_10876158_3	118166.JH976537_gene755	6.97e-27	113.0	COG1708@1|root,COG1708@2|Bacteria,1G8DN@1117|Cyanobacteria,1HC9X@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS1_k127_10876158_1	1142394.PSMK_18480	4.528e-32	132.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS1_k127_10880256_1	1121423.JONT01000026_gene893	3.681e-69	240.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,2608D@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
GDHHQS1_k127_10880256_0	1449126.JQKL01000002_gene1606	1.853e-141	455.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,2683I@186813|unclassified Clostridiales	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS1_k127_10903687_4	102125.Xen7305DRAFT_00046010	3.506e-28	120.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G0DF@1117|Cyanobacteria,3VM5A@52604|Pleurocapsales	1117|Cyanobacteria	OQ	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Peptidase_S8
GDHHQS1_k127_10903687_3	313595.P700755_003488	4.55e-36	157.0	COG1073@1|root,COG2931@1|root,COG1073@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS1_k127_10903687_1	556261.HMPREF0240_03745	1.876e-50	193.0	COG1879@1|root,COG1879@2|Bacteria,1VRHH@1239|Firmicutes,24RYJ@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
GDHHQS1_k127_10903687_0	313628.LNTAR_07951	2.318e-54	193.0	COG4146@1|root,COG4146@2|Bacteria	2|Bacteria	S	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_10927886_8	4558.Sb03g029120.1	4.304e-08	55.0	COG0563@1|root,KOG3078@2759|Eukaryota,37I3Q@33090|Viridiplantae,3GCGN@35493|Streptophyta,3KXMS@4447|Liliopsida	35493|Streptophyta	F	Belongs to the adenylate kinase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0030554,GO:0031090,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046872,GO:0046914,GO:0046940,GO:0050145,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:0097159,GO:0097367,GO:0098588,GO:0098805,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GDHHQS1_k127_10927886_1	1142394.PSMK_28980	2.056e-79	272.0	COG0024@1|root,COG0024@2|Bacteria,2IXPX@203682|Planctomycetes	203682|Planctomycetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS1_k127_10927886_6	643648.Slip_2213	2.062e-29	118.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,42K3D@68298|Syntrophomonadaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS1_k127_10927886_7	247490.KSU1_C1231	1.845e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS1_k127_10927886_4	886293.Sinac_0463	2.502e-46	169.0	COG0099@1|root,COG0099@2|Bacteria,2IZK8@203682|Planctomycetes	203682|Planctomycetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS1_k127_10927886_3	1210884.HG799465_gene12004	4.144e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS1_k127_10927886_2	580331.Thit_1945	1.113e-65	230.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS1_k127_10927886_0	1142394.PSMK_23760	1.516e-117	387.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS1_k127_10927886_5	880072.Desac_1427	3.729e-30	126.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MQIR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS1_k127_10936576_1	530564.Psta_3659	6.545e-71	247.0	COG0571@1|root,COG0571@2|Bacteria,2IYW1@203682|Planctomycetes	203682|Planctomycetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS1_k127_10936576_2	102125.Xen7305DRAFT_00030950	0.0003759	49.0	COG1366@1|root,COG1366@2|Bacteria,1GAKP@1117|Cyanobacteria,3VNGV@52604|Pleurocapsales	1117|Cyanobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
GDHHQS1_k127_10936576_0	945713.IALB_2801	3.648e-112	367.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS1_k127_1094331_1	572478.Vdis_0741	1.224e-40	155.0	COG1274@1|root,arCOG05865@2157|Archaea,2XPQX@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
GDHHQS1_k127_1094331_0	1235803.C825_01838	1.061e-122	418.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,2FWWY@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1094471_1	1449063.JMLS01000019_gene5685	1.172e-71	268.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,26RK2@186822|Paenibacillaceae	91061|Bacilli	GT	Phosphoenolpyruvate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
GDHHQS1_k127_1094471_0	1123278.KB893390_gene830	1.068e-82	281.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47TC8@768503|Cytophagia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
GDHHQS1_k127_10947445_6	177437.HRM2_39010	1.464e-25	113.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2MHME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS1_k127_10947445_0	596151.DesfrDRAFT_2197	1.272e-168	543.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2M9BY@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	plastoquinone (Complex I)	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
GDHHQS1_k127_10947445_5	290397.Adeh_3657	1.474e-55	201.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,42NDW@68525|delta/epsilon subdivisions,2WMF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydrogenase 4 membrane	ehrC	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
GDHHQS1_k127_10947445_2	269799.Gmet_2600	1.052e-97	327.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,43T74@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0374,iAF987.Gmet_2600	NADHdh
GDHHQS1_k127_10947445_1	1232410.KI421427_gene1299	8.144e-152	502.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS1_k127_10947445_3	886293.Sinac_2883	5.416e-87	293.0	COG1762@1|root,COG3311@1|root,COG1762@2|Bacteria,COG3311@2|Bacteria,2IZFY@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
GDHHQS1_k127_10947445_4	497964.CfE428DRAFT_1242	1.283e-78	278.0	COG0823@1|root,COG0823@2|Bacteria,46SJJ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10955166_2	1121085.AUCI01000004_gene1855	4.726e-30	125.0	COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HEAJ@91061|Bacilli,1ZR9S@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
GDHHQS1_k127_10955166_0	1123274.KB899412_gene1452	1.923e-131	430.0	COG0263@1|root,COG0263@2|Bacteria,2J6GB@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
GDHHQS1_k127_10955166_3	877418.ATWV01000015_gene2703	4.172e-17	88.0	2CCKR@1|root,32RW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10955166_1	398512.JQKC01000019_gene3416	5.742e-130	419.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS1_k127_10956680_1	595460.RRSWK_05042	7.093e-47	176.0	COG3622@1|root,COG3622@2|Bacteria,2IY93@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_10956680_0	574087.Acear_2299	0.0	1017.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia	186801|Clostridia	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS1_k127_10956680_2	1047013.AQSP01000091_gene642	0.0006648	44.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	sfrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.12.1.3,1.17.1.10,1.6.5.3	ko:K00335,ko:K15022,ko:K18331	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
GDHHQS1_k127_10996945_2	376686.Fjoh_2456	1.176e-11	78.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10996945_3	1121887.AUDK01000031_gene1036	2.488e-07	64.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_10996945_1	880070.Cycma_0727	4.251e-27	129.0	COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia	976|Bacteroidetes	S	Kelch repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_4,Kelch_6,Malectin,PKD
GDHHQS1_k127_10996945_0	357804.Ping_1819	7.565e-155	500.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS1_k127_10996945_4	522306.CAP2UW1_3926	4.677e-05	57.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1KQU2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
GDHHQS1_k127_11033901_1	391623.TERMP_00208	5.447e-181	576.0	COG1274@1|root,arCOG05865@2157|Archaea,2XUU1@28890|Euryarchaeota,24380@183968|Thermococci	183968|Thermococci	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
GDHHQS1_k127_11033901_0	926550.CLDAP_32400	4.609e-193	630.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF4038,DUF5060,DUF721
GDHHQS1_k127_11033901_2	886377.Murru_2329	8.266e-10	72.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
GDHHQS1_k127_11033901_3	794903.OPIT5_01130	3.947e-05	57.0	29M0T@1|root,32KIE@2|Bacteria,46YNA@74201|Verrucomicrobia,3K9VF@414999|Opitutae	414999|Opitutae	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS1_k127_11046605_2	1116472.MGMO_118c00010	1.97e-42	156.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,1SQ13@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS1_k127_11046605_1	247490.KSU1_B0010	1.963e-90	320.0	COG0358@1|root,COG0358@2|Bacteria,2IXQ4@203682|Planctomycetes	203682|Planctomycetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS1_k127_11046605_0	886293.Sinac_1564	2.109e-112	378.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS1_k127_11104881_3	1142394.PSMK_03880	1.171e-52	190.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_11104881_1	756272.Plabr_2024	3.975e-60	221.0	COG0299@1|root,COG0299@2|Bacteria,2IZ96@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS1_k127_11104881_6	555079.Toce_0936	1.81e-29	130.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia,42H5V@68295|Thermoanaerobacterales	186801|Clostridia	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
GDHHQS1_k127_11104881_7	944479.JQLX01000014_gene1556	8.634e-13	77.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WSCV@28221|Deltaproteobacteria,2M6CB@213113|Desulfurellales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS1_k127_11104881_0	1120973.AQXL01000135_gene1303	1.28e-71	256.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli	91061|Bacilli	E	succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS1_k127_11104881_5	368407.Memar_1122	7.869e-36	141.0	COG0454@1|root,arCOG00844@2157|Archaea,2Y70V@28890|Euryarchaeota,2NB0F@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GDHHQS1_k127_11104881_8	644283.Micau_2578	3.527e-12	70.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS1_k127_11104881_2	592015.HMPREF1705_01829	7.823e-59	219.0	COG1600@1|root,COG1600@2|Bacteria,3TBDW@508458|Synergistetes	508458|Synergistetes	C	Iron-sulfur cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_16
GDHHQS1_k127_11104881_4	1151292.QEW_1589	1.358e-43	174.0	COG0454@1|root,COG0456@2|Bacteria,1V562@1239|Firmicutes,24G6G@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS1_k127_1110905_1	886293.Sinac_2714	2.977e-100	342.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_1110905_0	575540.Isop_2477	1.176e-127	421.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_11114038_0	234267.Acid_1336	7.131e-203	638.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
GDHHQS1_k127_11114038_1	344747.PM8797T_15161	2.046e-103	351.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_11114038_2	1123508.JH636440_gene2112	1.307e-41	162.0	COG1262@1|root,COG1262@2|Bacteria,2IYGB@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS1_k127_11124362_1	880070.Cycma_0101	4.146e-96	327.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,47M78@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
GDHHQS1_k127_11124362_0	756272.Plabr_2112	6.956e-158	510.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_11124362_3	555779.Dthio_PD1075	4.722e-39	160.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria,2MH9Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_11124362_2	886293.Sinac_3140	1.096e-65	230.0	COG0253@1|root,COG0253@2|Bacteria,2IYCH@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS1_k127_11130557_1	504472.Slin_4675	6.324e-42	160.0	COG3394@1|root,COG3394@2|Bacteria,4PNAT@976|Bacteroidetes,47TGM@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GDHHQS1_k127_11130557_0	518766.Rmar_0773	8.016e-99	345.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,4NG31@976|Bacteroidetes,1FJXG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
GDHHQS1_k127_11131602_3	696747.NIES39_J01560	1.451e-22	113.0	COG1538@1|root,COG1538@2|Bacteria,1G0ZP@1117|Cyanobacteria,1H6YB@1150|Oscillatoriales	1117|Cyanobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_11131602_1	909663.KI867150_gene333	6.626e-162	533.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MQB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
GDHHQS1_k127_11131602_0	1142394.PSMK_16500	7.902e-206	662.0	COG1566@1|root,COG1994@1|root,COG1566@2|Bacteria,COG1994@2|Bacteria,2IWZT@203682|Planctomycetes	203682|Planctomycetes	M	PFAM peptidase	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	-
GDHHQS1_k127_11131602_2	1142394.PSMK_16490	1.367e-34	136.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS1_k127_11243705_0	344747.PM8797T_15341	1.421e-146	476.0	2DV29@1|root,33TNQ@2|Bacteria	2|Bacteria	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11243705_1	525904.Tter_2776	2.122e-21	109.0	COG2730@1|root,COG3386@1|root,COG5492@1|root,COG2730@2|Bacteria,COG3386@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.1.1.15	ko:K13874,ko:K22217	ko00053,ko01100,map00053,map01100	-	R02526	RC00537	ko00000,ko00001,ko01000	-	-	-	SGL
GDHHQS1_k127_11243705_2	1123236.KB899380_gene2799	1.217e-11	77.0	COG5492@1|root,COG5492@2|Bacteria,1Q99Y@1224|Proteobacteria,1RSE2@1236|Gammaproteobacteria,4649R@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
GDHHQS1_k127_11244594_2	1304874.JAFY01000001_gene2614	2.082e-42	180.0	COG3210@1|root,COG3291@1|root,COG4447@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_11244594_0	449447.MAE_49800	2.564e-119	422.0	COG4412@1|root,COG4412@2|Bacteria,1GE1J@1117|Cyanobacteria	1117|Cyanobacteria	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11244594_3	1303518.CCALI_01546	1.993e-12	77.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_11244594_1	756272.Plabr_3539	5.631e-76	269.0	COG0673@1|root,COG0673@2|Bacteria,2IX6I@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_11273465_1	1121904.ARBP01000001_gene5448	2.178e-114	378.0	COG2755@1|root,COG3669@1|root,COG2755@2|Bacteria,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Fucosidase_C
GDHHQS1_k127_11273465_0	1379698.RBG1_1C00001G0289	1.613e-202	644.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS1_k127_11273465_2	570967.JMLV01000014_gene2002	1.06e-38	152.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
GDHHQS1_k127_11350909_7	1123508.JH636439_gene995	7.44e-31	127.0	COG1820@1|root,COG1820@2|Bacteria,2IYHR@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS1_k127_11350909_8	383372.Rcas_3578	6.64e-18	86.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
GDHHQS1_k127_11350909_1	555079.Toce_0834	1.92e-131	429.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,42F8P@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS1_k127_11350909_3	237368.SCABRO_01249	8.041e-98	325.0	COG1013@1|root,COG1013@2|Bacteria,2J2M1@203682|Planctomycetes	203682|Planctomycetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
GDHHQS1_k127_11350909_4	572479.Hprae_1347	1.249e-55	200.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,3WB03@53433|Halanaerobiales	186801|Clostridia	C	PFAM Pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GDHHQS1_k127_11350909_0	886293.Sinac_3296	1.939e-169	541.0	COG1219@1|root,COG1219@2|Bacteria,2IXDS@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GDHHQS1_k127_11350909_2	1487953.JMKF01000011_gene5929	1.902e-123	404.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1HA14@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS1_k127_11350909_6	247490.KSU1_D1035	1.808e-40	164.0	COG1947@1|root,COG1947@2|Bacteria,2IZ7X@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS1_k127_11350909_5	575540.Isop_3729	1.356e-50	183.0	COG2088@1|root,COG2088@2|Bacteria,2IZR8@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SpoVG family	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
GDHHQS1_k127_11350909_9	886293.Sinac_1140	1.962e-05	51.0	COG2747@1|root,COG2747@2|Bacteria,2J17Q@203682|Planctomycetes	203682|Planctomycetes	KNU	PFAM Anti-sigma-28 factor FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
GDHHQS1_k127_11404764_0	763034.HMPREF9446_01013	1.5e-323	1017.0	COG3250@1|root,COG5492@1|root,COG3250@2|Bacteria,COG5492@2|Bacteria,4PKXA@976|Bacteroidetes,2FP7W@200643|Bacteroidia,4AN8Z@815|Bacteroidaceae	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,Lyase_8,Lyase_8_C,Lyase_8_N
GDHHQS1_k127_11404764_1	313606.M23134_07913	6.608e-69	244.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS1_k127_11404764_2	1304888.ATWF01000001_gene2370	2.715e-65	230.0	COG0841@1|root,COG0841@2|Bacteria,2GESU@200930|Deferribacteres	200930|Deferribacteres	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS1_k127_11438217_10	938288.HG326225_gene993	2.798e-05	48.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,248G3@186801|Clostridia,26AHK@186813|unclassified Clostridiales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS1_k127_11438217_6	1210884.HG799465_gene11839	2.255e-14	79.0	COG0594@1|root,COG0594@2|Bacteria,2J0QW@203682|Planctomycetes	203682|Planctomycetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS1_k127_11438217_8	314230.DSM3645_20057	5.543e-06	54.0	COG0355@1|root,COG0355@2|Bacteria,2J00X@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
GDHHQS1_k127_11438217_0	756272.Plabr_1194	2.554e-206	653.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS1_k127_11438217_2	1123242.JH636434_gene5161	2.831e-44	172.0	COG0224@1|root,COG0224@2|Bacteria,2IXDI@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GDHHQS1_k127_11438217_1	373903.Hore_17820	8.743e-195	620.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WAC5@53433|Halanaerobiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS1_k127_11438217_4	1131814.JAFO01000001_gene213	2.268e-21	100.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,3EZE2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GDHHQS1_k127_11438217_9	313628.LNTAR_02614	5.854e-06	55.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664	ATP-synt_B
GDHHQS1_k127_11438217_7	344747.PM8797T_28859	5.073e-13	72.0	COG0636@1|root,COG0636@2|Bacteria,2J0QD@203682|Planctomycetes	203682|Planctomycetes	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS1_k127_11438217_3	929556.Solca_3297	1.679e-39	157.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS1_k127_11438217_5	485917.Phep_2308	1.199e-20	91.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,1IX6E@117747|Sphingobacteriia	976|Bacteroidetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
GDHHQS1_k127_11454992_1	869213.JCM21142_3781	1.622e-69	250.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47M6F@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
GDHHQS1_k127_11454992_0	1047013.AQSP01000144_gene926	5.808e-218	689.0	COG3534@1|root,COG3534@2|Bacteria,2NQS6@2323|unclassified Bacteria	2|Bacteria	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS1_k127_11455717_4	1117108.PAALTS15_20843	1.427e-05	48.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,26RAP@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS1_k127_11455717_3	247490.KSU1_C0073	2.151e-13	78.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
GDHHQS1_k127_11455717_1	521674.Plim_4090	4.816e-45	169.0	COG1327@1|root,COG1327@2|Bacteria,2IZQ3@203682|Planctomycetes	203682|Planctomycetes	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
GDHHQS1_k127_11455717_0	1267535.KB906767_gene720	2.291e-53	198.0	COG0760@1|root,COG0760@2|Bacteria,3Y8EB@57723|Acidobacteria,2JNN9@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM PPIC-type	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
GDHHQS1_k127_11455717_2	1499967.BAYZ01000177_gene5729	2.174e-33	136.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
GDHHQS1_k127_11459336_2	118005.AWNK01000006_gene1240	1.659e-25	110.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS1_k127_11459336_1	383372.Rcas_3961	5.27e-37	143.0	COG2361@1|root,COG2361@2|Bacteria,2G8W4@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS1_k127_11459336_3	525897.Dbac_1475	6.787e-21	98.0	COG1669@1|root,COG1669@2|Bacteria,1NABR@1224|Proteobacteria,42WE0@68525|delta/epsilon subdivisions,2WRWK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS1_k127_11459336_0	237368.SCABRO_03813	1.979e-86	297.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
GDHHQS1_k127_11513694_0	756272.Plabr_2780	0.0	1108.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS1_k127_11513694_2	582515.KR51_00011320	6.06e-41	160.0	COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS1_k127_11513694_1	177437.HRM2_11540	1.483e-74	256.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2MJ22@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
GDHHQS1_k127_11522314_1	264732.Moth_0915	6.523e-51	185.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS1_k127_11522314_0	1121422.AUMW01000001_gene2339	2.465e-203	653.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS1_k127_11522314_2	1415779.JOMH01000001_gene2508	5.419e-46	169.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1X4D1@135614|Xanthomonadales	135614|Xanthomonadales	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS1_k127_11549645_1	1142394.PSMK_20610	4.183e-31	130.0	COG3494@1|root,COG3494@2|Bacteria,2IXGX@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
GDHHQS1_k127_11549645_0	237368.SCABRO_02585	4.343e-85	294.0	COG1044@1|root,COG1044@2|Bacteria,2IY8X@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS1_k127_11549645_2	247490.KSU1_D0452	9.1e-31	134.0	COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GDHHQS1_k127_11555841_2	697281.Mahau_1509	1.175e-09	63.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,42G0K@68295|Thermoanaerobacterales	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
GDHHQS1_k127_11555841_1	547042.BACCOPRO_01279	1.269e-18	100.0	COG2407@1|root,COG2407@2|Bacteria,4P1BT@976|Bacteroidetes,2FMIE@200643|Bacteroidia,4AKFB@815|Bacteroidaceae	976|Bacteroidetes	G	COG2407 L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11555841_0	1379698.RBG1_1C00001G0540	6.747e-106	362.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
GDHHQS1_k127_11573863_2	1244869.H261_14290	1.235e-18	94.0	COG3914@1|root,COG3914@2|Bacteria,1R5VF@1224|Proteobacteria,2U31E@28211|Alphaproteobacteria,2JUIU@204441|Rhodospirillales	204441|Rhodospirillales	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS1_k127_11573863_1	555779.Dthio_PD1364	7.835e-37	160.0	COG3642@1|root,COG3642@2|Bacteria,1QXJZ@1224|Proteobacteria,43D2P@68525|delta/epsilon subdivisions,2X89V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
GDHHQS1_k127_11573863_0	1123354.AUDR01000013_gene534	9.979e-49	198.0	COG1718@1|root,COG1718@2|Bacteria,1QY37@1224|Proteobacteria,2VKUD@28216|Betaproteobacteria	28216|Betaproteobacteria	DT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
GDHHQS1_k127_11573940_0	1123508.JH636439_gene627	4.238e-114	375.0	COG0343@1|root,COG0343@2|Bacteria,2IWXI@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS1_k127_11573940_2	1142394.PSMK_23640	1.477e-13	76.0	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS1_k127_11573940_1	1142394.PSMK_23630	1.515e-104	376.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
GDHHQS1_k127_11617387_3	1123008.KB905706_gene836	2.457e-129	430.0	2DSC1@1|root,33FFF@2|Bacteria,4P7M9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11617387_6	314278.NB231_17203	1.078e-11	66.0	2DRAI@1|root,33AYP@2|Bacteria,1NJXU@1224|Proteobacteria,1SHXT@1236|Gammaproteobacteria,1WZT8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11617387_5	1396418.BATQ01000003_gene1355	9.352e-48	189.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS1_k127_11617387_2	1396141.BATP01000004_gene5808	6.286e-138	448.0	COG2730@1|root,COG2730@2|Bacteria,46UVM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS1_k127_11617387_1	497964.CfE428DRAFT_4230	4.736e-150	490.0	COG3356@1|root,COG3356@2|Bacteria,46UC2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS1_k127_11617387_0	471854.Dfer_4490	1.021e-172	556.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11617387_4	1434325.AZQN01000012_gene3707	8.307e-75	259.0	COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,47MFM@768503|Cytophagia	976|Bacteroidetes	S	Putative oxidoreductase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Oxidoreduct_C
GDHHQS1_k127_11642130_1	1121904.ARBP01000006_gene3721	6.983e-110	366.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,47NF5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Sulfatase
GDHHQS1_k127_11642130_0	1267533.KB906739_gene2717	2.944e-154	512.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid_C,Bgal_small_N,Glyco_hydro_2,Glyco_hydro_28,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
GDHHQS1_k127_11642130_2	545694.TREPR_1522	5.972e-86	289.0	COG0407@1|root,COG0407@2|Bacteria,2J9RK@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
GDHHQS1_k127_11651130_2	1123508.JH636445_gene6685	4.603e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_11651130_3	1127673.GLIP_1223	0.0004091	51.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1S13F@1236|Gammaproteobacteria,466IW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_19,TPR_8
GDHHQS1_k127_11651130_0	382464.ABSI01000010_gene3488	9.542e-200	637.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_11651130_1	180332.JTGN01000016_gene1023	4.778e-120	396.0	COG0407@1|root,COG0407@2|Bacteria,1VJHK@1239|Firmicutes,24TV3@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
GDHHQS1_k127_11739875_1	1340493.JNIF01000003_gene2252	1.424e-147	479.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
GDHHQS1_k127_11739875_0	439235.Dalk_2563	2.576e-194	615.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
GDHHQS1_k127_11739875_2	177437.HRM2_00880	1.481e-25	112.0	COG3005@1|root,COG3005@2|Bacteria,1RIC0@1224|Proteobacteria,42NW0@68525|delta/epsilon subdivisions,2WK0R@28221|Deltaproteobacteria,2MJCY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NapC NirT cytochrome c	-	-	-	ko:K02569,ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
GDHHQS1_k127_11739875_3	1047013.AQSP01000144_gene912	2.949e-25	107.0	COG1959@1|root,COG1959@2|Bacteria,2NQ8B@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, BadM Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS1_k127_11868241_3	1121472.AQWN01000011_gene1214	3.651e-30	124.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,2607U@186807|Peptococcaceae	186801|Clostridia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GDHHQS1_k127_11868241_0	886293.Sinac_5717	1.813e-272	849.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_11868241_2	344747.PM8797T_26590	4.913e-101	338.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS1_k127_11868241_1	509191.AEDB02000002_gene1137	2.682e-115	405.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_11868241_4	643562.Daes_1381	5.384e-09	58.0	COG1454@1|root,COG1454@2|Bacteria,1R8D1@1224|Proteobacteria,43BGS@68525|delta/epsilon subdivisions,2WTMB@28221|Deltaproteobacteria,2MH7A@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS1_k127_118933_1	344747.PM8797T_04520	1.949e-85	302.0	COG0593@1|root,COG0593@2|Bacteria,2IWXU@203682|Planctomycetes	203682|Planctomycetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS1_k127_118933_2	886293.Sinac_4979	2.123e-54	197.0	COG0440@1|root,COG0440@2|Bacteria,2IZ6Q@203682|Planctomycetes	203682|Planctomycetes	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
GDHHQS1_k127_118933_0	237368.SCABRO_03824	1.873e-177	566.0	COG0028@1|root,COG0028@2|Bacteria,2IXMU@203682|Planctomycetes	203682|Planctomycetes	H	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS1_k127_11907948_2	909613.UO65_5595	3.926e-63	222.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DYBI@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	2.6.1.106	ko:K13310	ko00523,ko01130,map00523,map01130	M00797	R06426	RC00006,RC01514	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_11907948_0	246197.MXAN_2689	7.748e-174	555.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2YTWM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_11907948_1	471223.GWCH70_3255	1.297e-74	262.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	ATP-grasp_3,Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS1_k127_11907948_3	1304880.JAGB01000002_gene1921	1.341e-33	136.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
GDHHQS1_k127_11912058_1	338963.Pcar_1613	1.839e-59	209.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS1_k127_11912058_0	247490.KSU1_B0128	0.0	1448.0	COG0458@1|root,COG0458@2|Bacteria,2IXR6@203682|Planctomycetes	203682|Planctomycetes	F	Carbamoylphosphate synthase large subunit	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS1_k127_11930892_1	344747.PM8797T_11556	9.188e-110	369.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_11930892_2	595460.RRSWK_06263	1.265e-70	263.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS1_k127_11930892_0	485917.Phep_0352	9.481e-166	529.0	COG0399@1|root,COG0399@2|Bacteria,4NJKH@976|Bacteroidetes,1IURF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_11967195_0	247490.KSU1_B0556	1.831e-75	262.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_11967195_2	1179778.PMM47T1_20463	5.159e-57	205.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS1_k127_11967195_1	518766.Rmar_0625	4.823e-61	220.0	COG1515@1|root,COG1515@2|Bacteria,4NI4J@976|Bacteroidetes,1FK2J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
GDHHQS1_k127_11967195_4	909663.KI867150_gene237	3.065e-23	100.0	2E32Y@1|root,32Y36@2|Bacteria,1N7G2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11967195_5	555779.Dthio_PD1777	2.656e-20	93.0	2EE3Q@1|root,337YA@2|Bacteria,1Q4K8@1224|Proteobacteria,42WYG@68525|delta/epsilon subdivisions,2WSS5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS1_k127_11967195_3	96561.Dole_1478	5.414e-24	102.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,42VC8@68525|delta/epsilon subdivisions,2WS7K@28221|Deltaproteobacteria,2MM1P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS1_k127_11993306_1	272633.26454399	1.605e-37	147.0	COG0821@1|root,COG0821@2|Bacteria,3WT3N@544448|Tenericutes	544448|Tenericutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS1_k127_11993306_0	1121904.ARBP01000022_gene3520	7.244e-69	249.0	COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_11993306_2	935839.JAGJ01000016_gene2400	2.284e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4F4BB@85017|Promicromonosporaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS1_k127_12038505_5	1142394.PSMK_14460	1.249e-52	198.0	COG0061@1|root,COG0061@2|Bacteria,2IXD3@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS1_k127_12038505_0	247490.KSU1_D0796	5.487e-180	583.0	COG1154@1|root,COG1154@2|Bacteria,2IYHC@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GDHHQS1_k127_12038505_4	429009.Adeg_0859	2.187e-63	237.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,42EKD@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
GDHHQS1_k127_12038505_3	397290.C810_05076	5.208e-65	236.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,27IM1@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS1_k127_12038505_6	351348.Maqu_0043	4.867e-36	143.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,466J1@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS1_k127_12038505_2	1396418.BATQ01000125_gene5082	5.009e-77	269.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,2IU2S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
GDHHQS1_k127_12038505_1	344747.PM8797T_30332	1.238e-81	279.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS1_k127_12052628_2	411470.RUMGNA_01538	6.116e-08	60.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3XYWH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
GDHHQS1_k127_12052628_0	344747.PM8797T_18384	6.454e-122	406.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_12052628_1	1242864.D187_001948	2.032e-27	123.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS1_k127_12054224_3	1163408.UU9_08685	1.365e-21	111.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1S6N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_12054224_2	1121472.AQWN01000003_gene1464	3.827e-27	114.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,260BG@186807|Peptococcaceae	186801|Clostridia	E	PFAM peptidase M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS1_k127_12054224_0	580331.Thit_1074	1.334e-46	177.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,42F13@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM peptidase M24	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS1_k127_12054224_1	1142394.PSMK_31720	1.04e-35	151.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS1_k127_12054224_4	756272.Plabr_4525	6.01e-17	93.0	2E5SS@1|root,330H5@2|Bacteria,2J0J5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12062285_0	1262449.CP6013_0796	5.595e-95	325.0	COG3664@1|root,COG3664@2|Bacteria,1VTGP@1239|Firmicutes	1239|Firmicutes	G	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
GDHHQS1_k127_12062285_1	1122963.AUHB01000019_gene49	3.757e-37	153.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2TSUM@28211|Alphaproteobacteria,370WQ@31993|Methylocystaceae	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS1_k127_12062285_2	1344012.ATMI01000031_gene2738	7.501e-31	122.0	2DMJC@1|root,32RYJ@2|Bacteria,1RGW8@1224|Proteobacteria,1S6NK@1236|Gammaproteobacteria,4BVUD@82986|Tatumella	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4186)	yneG	-	-	-	-	-	-	-	-	-	-	-	DUF4186
GDHHQS1_k127_12069078_0	344747.PM8797T_28904	6.211e-126	436.0	COG1520@1|root,COG1957@1|root,COG1520@2|Bacteria,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,DUF547,PQQ_2,PQQ_3
GDHHQS1_k127_12096182_0	1286171.EAL2_c20220	5.778e-51	187.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,25VSZ@186806|Eubacteriaceae	186801|Clostridia	GM	CoA-binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
GDHHQS1_k127_12096182_1	398512.JQKC01000004_gene5235	4.989e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WIW4@541000|Ruminococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_12104760_2	376686.Fjoh_2456	9.196e-13	78.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12104760_0	886293.Sinac_6245	3.253e-143	471.0	COG1052@1|root,COG1052@2|Bacteria,2J557@203682|Planctomycetes	203682|Planctomycetes	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS1_k127_12104760_1	1304888.ATWF01000002_gene48	1.342e-52	194.0	COG0642@1|root,COG2205@2|Bacteria	1304888.ATWF01000002_gene48|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12109365_1	234267.Acid_1705	1.116e-110	362.0	COG3828@1|root,COG3828@2|Bacteria,3Y748@57723|Acidobacteria	57723|Acidobacteria	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS1_k127_12109365_2	530564.Psta_2150	2.401e-93	321.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_12109365_0	1120968.AUBX01000018_gene2167	4.448e-150	488.0	COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_12193557_3	1280944.HY17_18820	7.241e-12	75.0	2DR6B@1|root,33ACQ@2|Bacteria,1NI4T@1224|Proteobacteria,2UKEW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12193557_1	247490.KSU1_D0951	1.79e-68	244.0	COG1940@1|root,COG1940@2|Bacteria,2IYBR@203682|Planctomycetes	203682|Planctomycetes	GK	transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS1_k127_12193557_0	696369.KI912183_gene2079	1.955e-113	374.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,2609J@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS1_k127_12193557_4	344747.PM8797T_21473	0.0007889	49.0	2C65R@1|root,3318E@2|Bacteria,2J0VS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12193557_2	1121904.ARBP01000040_gene522	2.502e-46	169.0	COG0823@1|root,COG0823@2|Bacteria,4NQ0C@976|Bacteroidetes,47PP7@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12202859_0	1121396.KB893103_gene1771	1.551e-157	511.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMR2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
GDHHQS1_k127_12202859_1	941824.TCEL_00749	1.554e-131	428.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36DJA@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
GDHHQS1_k127_12228525_0	690850.Desaf_3621	3.432e-242	765.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS1_k127_12228525_1	690850.Desaf_3620	1.744e-117	391.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2M8ZY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
GDHHQS1_k127_12308526_0	903818.KI912268_gene1005	0.0	1206.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria	57723|Acidobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS1_k127_12335401_3	497964.CfE428DRAFT_0571	8.884e-35	154.0	COG3525@1|root,COG3525@2|Bacteria,46SS5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
GDHHQS1_k127_12335401_0	497964.CfE428DRAFT_6049	1.705e-143	469.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_12335401_1	645991.Sgly_1634	2.52e-84	289.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,25KQ6@186801|Clostridia,264CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS1_k127_12335401_2	65093.PCC7418_0889	4.81e-62	219.0	COG2905@1|root,COG2905@2|Bacteria,1GPZ1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
GDHHQS1_k127_12343569_0	886293.Sinac_6948	1.022e-253	792.0	COG0665@1|root,COG0665@2|Bacteria,2J4YV@203682|Planctomycetes	203682|Planctomycetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS1_k127_12343569_1	794903.OPIT5_12240	2.326e-73	267.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
GDHHQS1_k127_12343569_3	1382306.JNIM01000001_gene1984	1.124e-45	174.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2,Peptidase_M22
GDHHQS1_k127_12343569_2	515635.Dtur_1709	2.294e-47	176.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GDHHQS1_k127_12357672_1	595460.RRSWK_03108	2.253e-14	74.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_12357672_0	452637.Oter_1254	1.334e-121	400.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
GDHHQS1_k127_12420495_0	886293.Sinac_5251	6.761e-107	361.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
GDHHQS1_k127_12420495_2	316067.Geob_2252	3.206e-41	157.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS1_k127_12428283_1	313628.LNTAR_12216	1.445e-25	115.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_12428283_2	1410633.JHWR01000001_gene1352	1.691e-18	91.0	COG3584@1|root,COG3584@2|Bacteria,1VGG7@1239|Firmicutes,259JY@186801|Clostridia,27NSC@186928|unclassified Lachnospiraceae	186801|Clostridia	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3
GDHHQS1_k127_12428283_3	1396141.BATP01000003_gene4864	1.236e-15	91.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
GDHHQS1_k127_12428283_0	485917.Phep_2066	5.634e-37	158.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_12428283_4	474922.ELA35872	1.978e-07	62.0	COG0823@1|root,2QPTW@2759|Eukaryota,38RVS@33154|Opisthokonta,3NZ8B@4751|Fungi,3QSE5@4890|Ascomycota,218QP@147550|Sordariomycetes,1EXG1@1028384|Glomerellales	4751|Fungi	U	WD40 domain protein beta propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_12528218_2	1185876.BN8_04811	6.176e-07	57.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GDHHQS1_k127_12528218_0	1403819.BATR01000017_gene540	5.862e-163	526.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS1_k127_12528218_1	1340493.JNIF01000003_gene2296	7.702e-117	387.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	ko:K18106	ko00040,ko01100,map00040,map01100	M00630	R07676,R10565	RC00108	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_12539543_4	1246484.D479_13617	1.901e-73	253.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3ND54@45667|Halobacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_12539543_7	488538.SAR116_1354	5.222e-05	55.0	2BZ7H@1|root,34C4G@2|Bacteria,1P3BN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12539543_0	1396418.BATQ01000041_gene6309	8.109e-123	412.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,2ITH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
GDHHQS1_k127_12539543_6	488538.SAR116_1356	8.755e-21	106.0	COG3793@1|root,COG3793@2|Bacteria,1NS76@1224|Proteobacteria	1224|Proteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
GDHHQS1_k127_12539543_1	497964.CfE428DRAFT_5038	4.434e-112	378.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GDHHQS1_k127_12539543_2	1403819.BATR01000137_gene4831	7.497e-110	370.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_12539543_5	497964.CfE428DRAFT_4944	4.624e-68	238.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS1_k127_12539543_3	497964.CfE428DRAFT_4943	2.307e-90	314.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
GDHHQS1_k127_12553507_2	363253.LI0700	6.55e-07	53.0	COG0457@1|root,COG0457@2|Bacteria,1REFJ@1224|Proteobacteria,42REI@68525|delta/epsilon subdivisions,2WN9F@28221|Deltaproteobacteria,2MB58@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS1_k127_12553507_1	338966.Ppro_3338	1.889e-36	156.0	COG1032@1|root,COG1216@1|root,COG1032@2|Bacteria,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions,2WPIS@28221|Deltaproteobacteria,43V77@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
GDHHQS1_k127_12553507_0	443254.Marpi_1037	1.502e-68	252.0	COG0438@1|root,COG0457@1|root,COG1887@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1887@2|Bacteria,2GC5K@200918|Thermotogae	200918|Thermotogae	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,TPR_2
GDHHQS1_k127_12553507_3	1121430.JMLG01000015_gene1857	7.615e-07	54.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia,261R5@186807|Peptococcaceae	186801|Clostridia	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
GDHHQS1_k127_12553519_3	886379.AEWI01000044_gene3146	8.409e-22	106.0	COG0229@1|root,COG0229@2|Bacteria,4PPXG@976|Bacteroidetes,2G1A3@200643|Bacteroidia,3XK63@558415|Marinilabiliaceae	976|Bacteroidetes	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
GDHHQS1_k127_12553519_2	1089552.KI911559_gene1786	7.593e-29	126.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,2TWCH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Complex I intermediate-associated protein 30 (CIA30)	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
GDHHQS1_k127_12553519_4	640513.Entas_3130	1.264e-14	86.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,1RMIG@1236|Gammaproteobacteria,3X0QI@547|Enterobacter	1236|Gammaproteobacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
GDHHQS1_k127_12553519_0	344747.PM8797T_05400	5.532e-87	309.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_12553519_1	452637.Oter_0134	4.199e-50	199.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase,DUF4038,DUF5060,Glyco_hydro_115
GDHHQS1_k127_1256310_0	1123508.JH636439_gene943	8.988e-88	303.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Calx-beta,DUF1863,PQQ,PQQ_2,PQQ_3,P_proprotein,Peptidase_S8,SBBP,VCBS
GDHHQS1_k127_1256310_1	632292.Calhy_1745	5.433e-43	175.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS1_k127_1256310_2	1122605.KB893648_gene3690	2.142e-12	68.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
GDHHQS1_k127_12582508_6	635013.TherJR_0270	8.375e-13	69.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS1_k127_12582508_1	1142394.PSMK_30320	6.124e-41	157.0	COG0817@1|root,COG0817@2|Bacteria,2IZJS@203682|Planctomycetes	203682|Planctomycetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS1_k127_12582508_3	96561.Dole_2206	1.697e-24	111.0	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
GDHHQS1_k127_12582508_0	1536769.P40081_29910	1.061e-117	387.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS1_k127_12582508_5	272624.lpg1633	1.816e-15	85.0	2D6MI@1|root,30AQT@2|Bacteria,1P8HC@1224|Proteobacteria,1T7XG@1236|Gammaproteobacteria,1JFZQ@118969|Legionellales	118969|Legionellales	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
GDHHQS1_k127_12582508_2	1123508.JH636445_gene6737	8.641e-32	134.0	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS1_k127_12582508_4	237368.SCABRO_01971	2.388e-16	85.0	COG0319@1|root,COG0319@2|Bacteria,2J0MV@203682|Planctomycetes	203682|Planctomycetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS1_k127_1260578_0	243090.RB7879	1.875e-117	390.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_1260578_1	1267535.KB906767_gene3349	1.388e-106	355.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_1260578_2	1499967.BAYZ01000076_gene806	1.385e-56	201.0	COG1028@1|root,COG1028@2|Bacteria,2NQY3@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS1_k127_12674785_1	706587.Desti_0850	3.905e-59	228.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_12674785_0	743719.PaelaDRAFT_0458	3.94e-78	273.0	COG1082@1|root,COG1082@2|Bacteria,1V2HT@1239|Firmicutes,4HFBJ@91061|Bacilli,26V9V@186822|Paenibacillaceae	91061|Bacilli	G	Xylulose 5-phosphate 3-epimerase	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_12674785_2	349741.Amuc_0216	0.0004861	48.0	COG3345@1|root,COG3345@2|Bacteria,46XJC@74201|Verrucomicrobia,2IW2A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12721537_3	344747.PM8797T_14624	3.901e-33	146.0	COG0750@1|root,COG0793@1|root,COG0750@2|Bacteria,COG0793@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GDHHQS1_k127_12721537_1	237368.SCABRO_01800	5.004e-112	374.0	COG0743@1|root,COG0743@2|Bacteria,2IY3M@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS1_k127_12721537_2	1142394.PSMK_13910	2.377e-109	364.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
GDHHQS1_k127_12721537_5	886293.Sinac_5501	1.847e-15	85.0	COG0177@1|root,COG0177@2|Bacteria,2IZDJ@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GDHHQS1_k127_12721537_4	309801.trd_0772	1.083e-15	82.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi,27YJU@189775|Thermomicrobia	189775|Thermomicrobia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS1_k127_12721537_0	237368.SCABRO_03706	8.393e-181	590.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GDHHQS1_k127_12732957_0	926561.KB900620_gene3112	2.525e-146	483.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
GDHHQS1_k127_12732957_3	1189612.A33Q_0332	5.79e-60	218.0	COG0791@1|root,COG0791@2|Bacteria,4PM8G@976|Bacteroidetes,47PGA@768503|Cytophagia	976|Bacteroidetes	M	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
GDHHQS1_k127_12732957_4	316067.Geob_0799	4.89e-41	155.0	COG1310@1|root,COG1310@2|Bacteria,1N3TI@1224|Proteobacteria,42TY4@68525|delta/epsilon subdivisions,2WW9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Mov34 MPN PAD-1 family protein	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GDHHQS1_k127_12732957_2	589865.DaAHT2_0870	1.341e-114	376.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2MK1G@213118|Desulfobacterales	28221|Deltaproteobacteria	H	ThiF family	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS1_k127_12732957_6	926561.KB900620_gene3115	2.698e-19	89.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia	186801|Clostridia	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS1_k127_12732957_1	269799.Gmet_1566	1.876e-140	457.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	metY-3	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS1_k127_12732957_5	575540.Isop_0838	3.942e-39	154.0	COG0175@1|root,COG0175@2|Bacteria,2IWXW@203682|Planctomycetes	203682|Planctomycetes	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
GDHHQS1_k127_12732957_7	720554.Clocl_0516	2.803e-09	59.0	COG1118@1|root,COG1118@2|Bacteria,1UI6I@1239|Firmicutes,25EK4@186801|Clostridia,3WGGX@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
GDHHQS1_k127_12768874_3	472175.EL18_01924	0.0003189	45.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2U45F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_12768874_0	861299.J421_5653	1.151e-140	462.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_12768874_2	497964.CfE428DRAFT_0981	3.683e-97	340.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_12768874_1	1123278.KB893579_gene863	9.008e-99	344.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_12777827_1	643648.Slip_0127	2.928e-58	219.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42JX4@68298|Syntrophomonadaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS1_k127_12777827_3	1210884.HG799465_gene12149	1.056e-22	108.0	2EPQ7@1|root,33HAS@2|Bacteria,2J1P9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12777827_4	926549.KI421517_gene3935	8.904e-12	77.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,47QC0@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
GDHHQS1_k127_12777827_2	1089553.Tph_c27210	7.305e-27	115.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,42H9A@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM regulatory protein GntR HTH	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GDHHQS1_k127_12777827_0	1123242.JH636434_gene4731	6.781e-69	246.0	COG1131@1|root,COG1131@2|Bacteria,2IZVY@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_12794619_6	1121441.AUCX01000004_gene3150	1.188e-71	248.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2M883@213115|Desulfovibrionales	28221|Deltaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
GDHHQS1_k127_12794619_13	1123489.AUAN01000006_gene1766	9.342e-11	69.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GDHHQS1_k127_12794619_4	635013.TherJR_1303	9.659e-107	356.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,260QH@186807|Peptococcaceae	186801|Clostridia	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
GDHHQS1_k127_12794619_3	335543.Sfum_4014	2.5e-111	370.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2MR11@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
GDHHQS1_k127_12794619_12	1120985.AUMI01000014_gene886	6.049e-17	82.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,4H5P1@909932|Negativicutes	909932|Negativicutes	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
GDHHQS1_k127_12794619_2	926550.CLDAP_28600	1.055e-113	374.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS1_k127_12794619_1	1232410.KI421424_gene1631	2.782e-198	644.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,43S2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GDHHQS1_k127_12794619_7	1499967.BAYZ01000097_gene4355	1.333e-60	218.0	COG2426@1|root,COG2426@2|Bacteria	2|Bacteria	S	small multidrug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
GDHHQS1_k127_12794619_8	1485544.JQKP01000001_gene1151	1.366e-50	186.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS1_k127_12794619_11	768706.Desor_4420	9.73e-22	109.0	COG5598@1|root,COG5598@2|Bacteria,1TR30@1239|Firmicutes,24CK1@186801|Clostridia	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS1_k127_12794619_10	344747.PM8797T_12533	6.825e-22	100.0	2DMM9@1|root,32SDB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12794619_5	530564.Psta_2150	3.775e-95	327.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_12794619_0	929562.Emtol_2946	5.534e-201	641.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS1_k127_12794619_14	882086.SacxiDRAFT_1746	7.925e-06	53.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4E2HU@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1280589_1	1235788.C802_00423	7.967e-35	136.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,2FM6N@200643|Bacteroidia,4AKJJ@815|Bacteroidaceae	976|Bacteroidetes	V	Psort location Cytoplasmic, score 9.12	yxlF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_1280589_2	1177181.T9A_02438	5.046e-30	123.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria,1XKXI@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
GDHHQS1_k127_1280589_0	497964.CfE428DRAFT_5266	3.955e-138	451.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_12866677_0	1304885.AUEY01000042_gene3609	2.373e-210	677.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,2MIS5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS1_k127_12866677_1	761193.Runsl_0688	4.67e-109	358.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
GDHHQS1_k127_1287119_2	1210884.HG799462_gene7943	8.92e-70	247.0	COG0621@1|root,COG0621@2|Bacteria,2IWTE@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS1_k127_1287119_7	1123371.ATXH01000016_gene1861	1.187e-16	94.0	COG1450@1|root,COG1450@2|Bacteria,2GI8Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Bacterial type II/III secretion system short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
GDHHQS1_k127_1287119_1	1142394.PSMK_21340	2.439e-75	263.0	COG0052@1|root,COG0052@2|Bacteria,2IY9P@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS1_k127_1287119_3	387092.NIS_1536	2.662e-62	225.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS1_k127_1287119_0	290397.Adeh_0280	2.789e-80	274.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2YU4R@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS1_k127_1287119_4	1123242.JH636435_gene1332	6.319e-50	184.0	COG0233@1|root,COG0233@2|Bacteria,2IYYY@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS1_k127_1287119_5	530564.Psta_2133	2.338e-28	134.0	COG3164@1|root,COG3164@2|Bacteria,2IXXM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1287119_6	1523503.JPMY01000041_gene494	2.874e-20	101.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	UPF0761 membrane protein	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS1_k127_12874272_3	247490.KSU1_C1279	4.507e-40	153.0	COG0535@1|root,COG0535@2|Bacteria,2IZE3@203682|Planctomycetes	203682|Planctomycetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_12874272_0	247490.KSU1_B0678	1.585e-141	460.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	nirJ	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS1_k127_12874272_2	880073.Calab_3405	3.593e-49	197.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS1_k127_12874272_1	1191523.MROS_1494	4.314e-141	461.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_12927382_1	697281.Mahau_1084	2.168e-48	175.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS1_k127_12927382_0	886293.Sinac_0515	5.403e-104	358.0	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
GDHHQS1_k127_12927382_3	748727.CLJU_c37820	2.42e-15	82.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,36FKV@31979|Clostridiaceae	186801|Clostridia	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS1_k127_12927382_2	1121289.JHVL01000036_gene2591	2.608e-19	91.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,36E5T@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
GDHHQS1_k127_12941614_2	706587.Desti_0632	3.827e-27	114.0	COG1708@1|root,COG1708@2|Bacteria,1NIDP@1224|Proteobacteria,433AV@68525|delta/epsilon subdivisions,2WY5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS1_k127_12941614_3	768671.ThimaDRAFT_4613	1.413e-18	90.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_12941614_0	335541.Swol_1078	7.722e-42	178.0	COG5492@1|root,COG5492@2|Bacteria,1V7TS@1239|Firmicutes,25F4B@186801|Clostridia,42KX4@68298|Syntrophomonadaceae	1239|Firmicutes	N	Surface proteins containing Ig-like domains-like	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12941614_1	323259.Mhun_0432	8.953e-33	148.0	arCOG03579@1|root,arCOG03579@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12941849_2	1268240.ATFI01000005_gene4564	1.97e-77	273.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,2FMZR@200643|Bacteroidia,4AP7B@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
GDHHQS1_k127_12941849_1	530564.Psta_2822	1.149e-98	337.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_12941849_0	1403819.BATR01000096_gene3164	3.118e-116	390.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12941849_3	1288963.ADIS_1775	6.053e-70	246.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12955064_6	697281.Mahau_2161	4.743e-53	189.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,42GED@68295|Thermoanaerobacterales	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS1_k127_12955064_5	886293.Sinac_0492	7.169e-61	214.0	COG0049@1|root,COG0049@2|Bacteria,2IZ7I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS1_k127_12955064_0	289376.THEYE_A1449	5.797e-225	717.0	COG0480@1|root,COG0480@2|Bacteria,3J0EK@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS1_k127_12955064_9	1142394.PSMK_29190	6.718e-45	165.0	COG0051@1|root,COG0051@2|Bacteria,2IZQR@203682|Planctomycetes	203682|Planctomycetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GDHHQS1_k127_12955064_4	1051006.HMPREF1162_2014	6.629e-61	217.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4DNWZ@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GDHHQS1_k127_12955064_12	247490.KSU1_C1209	3.753e-41	159.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GDHHQS1_k127_12955064_17	530564.Psta_2602	3.323e-20	93.0	COG0089@1|root,COG0089@2|Bacteria,2J0VE@203682|Planctomycetes	203682|Planctomycetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
GDHHQS1_k127_12955064_1	756272.Plabr_2060	3.425e-107	354.0	COG0090@1|root,COG0090@2|Bacteria,2IXD9@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
GDHHQS1_k127_12955064_13	237368.SCABRO_03502	3.169e-35	136.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
GDHHQS1_k127_12955064_18	395493.BegalDRAFT_2619	1.262e-14	81.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
GDHHQS1_k127_12955064_2	1142394.PSMK_29120	1.386e-71	250.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
GDHHQS1_k127_12955064_7	580331.Thit_1965	5.016e-52	186.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,42G0F@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
GDHHQS1_k127_12955064_19	314282.PCNPT3_01070	0.0007529	46.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,2QIE2@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
GDHHQS1_k127_12955064_15	318161.Sden_0179	1.589e-22	99.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,2QC7Q@267890|Shewanellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
GDHHQS1_k127_12955064_10	530564.Psta_2610	7.372e-43	160.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
GDHHQS1_k127_12955064_14	360911.EAT1b_1622	1.064e-25	112.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3WEZB@539002|Bacillales incertae sedis	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
GDHHQS1_k127_12955064_3	1191523.MROS_0204	2.803e-66	231.0	COG0094@1|root,COG0094@2|Bacteria	2|Bacteria	J	tRNA binding	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
GDHHQS1_k127_12955064_16	1229780.BN381_450084	1.436e-20	92.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,3UXRU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein S14p/S29e	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
GDHHQS1_k127_12955064_11	401526.TcarDRAFT_1011	5.366e-42	158.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4H4AT@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
GDHHQS1_k127_12955064_8	756272.Plabr_2071	3.249e-49	181.0	COG0097@1|root,COG0097@2|Bacteria,2IZ8X@203682|Planctomycetes	203682|Planctomycetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GDHHQS1_k127_12973512_4	397288.C806_01827	7.494e-14	74.0	COG2148@1|root,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,27JIX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GDHHQS1_k127_12973512_5	530564.Psta_0544	6.697e-08	63.0	COG5652@1|root,COG5652@2|Bacteria,2J19Q@203682|Planctomycetes	203682|Planctomycetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS1_k127_12973512_1	225937.HP15_1897	5.778e-72	258.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
GDHHQS1_k127_12973512_2	1255043.TVNIR_3004	1.79e-39	163.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS1_k127_12973512_3	161156.JQKW01000008_gene469	5.675e-34	146.0	COG0693@1|root,COG0693@2|Bacteria,2GGYK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS1_k127_12973512_0	644282.Deba_1154	3.21e-170	552.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS1_k127_12973512_6	1112217.PPL19_11893	3.356e-06	51.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
GDHHQS1_k127_12993590_4	1499967.BAYZ01000096_gene4315	4.567e-13	80.0	COG0421@1|root,COG0421@2|Bacteria,2NNTV@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
GDHHQS1_k127_12993590_2	96561.Dole_2431	7.078e-15	77.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42MDS@68525|delta/epsilon subdivisions,2WJM3@28221|Deltaproteobacteria,2MMPT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
GDHHQS1_k127_12993590_0	1123288.SOV_3c01310	5.62e-47	178.0	COG1571@1|root,COG1571@2|Bacteria,1V2YE@1239|Firmicutes	1239|Firmicutes	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_12993590_5	1142394.PSMK_04880	5.292e-07	59.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_12993590_1	240016.ABIZ01000001_gene5734	1.571e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia,2IVV9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
GDHHQS1_k127_13012667_1	1463861.JNXE01000002_gene6359	1.183e-05	49.0	COG3408@1|root,COG3408@2|Bacteria,2H2QX@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
GDHHQS1_k127_13012667_0	344747.PM8797T_28229	4.489e-91	320.0	COG3866@1|root,COG3866@2|Bacteria,2IZ3T@203682|Planctomycetes	203682|Planctomycetes	M	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS1_k127_13057253_0	1396141.BATP01000027_gene1160	7.559e-57	227.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_13057253_3	1121285.AUFK01000009_gene1148	1.331e-13	85.0	COG4733@1|root,COG4733@2|Bacteria,4PKYK@976|Bacteroidetes,1IJHK@117743|Flavobacteriia,3ZQWF@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Pec_lyase_C,fn3
GDHHQS1_k127_13057253_1	497964.CfE428DRAFT_1163	1.227e-36	161.0	COG3506@1|root,COG4254@1|root,COG3506@2|Bacteria,COG4254@2|Bacteria,46SQ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lyase_8,Lyase_N,Lyase_catalyt
GDHHQS1_k127_13057253_2	1395513.P343_17790	6.282e-25	111.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26NR0@186821|Sporolactobacillaceae	91061|Bacilli	K	ECF sigma factor	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1314772_1	192952.MM_1144	2.101e-18	101.0	COG5563@1|root,arCOG03499@1|root,arCOG03499@2157|Archaea,arCOG03501@2157|Archaea	2157|Archaea	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
GDHHQS1_k127_1314772_0	1195236.CTER_4883	3.243e-119	415.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
GDHHQS1_k127_1314772_2	1250232.JQNJ01000001_gene475	9.034e-13	82.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I0C1@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_1314772_3	1121897.AUGO01000006_gene583	2.267e-10	74.0	COG4733@1|root,COG4733@2|Bacteria,4PN6W@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1314772_5	314230.DSM3645_13675	0.0001288	55.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,Laminin_G_3
GDHHQS1_k127_1314772_4	497964.CfE428DRAFT_1649	2.31e-09	70.0	COG3506@1|root,COG4254@1|root,COG3506@2|Bacteria,COG4254@2|Bacteria,46SQ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lyase_8,Lyase_N,Lyase_catalyt
GDHHQS1_k127_13150739_1	1142394.PSMK_23630	9.471e-53	197.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
GDHHQS1_k127_13150739_4	755731.Clo1100_3020	2.818e-08	63.0	COG1652@1|root,COG1652@2|Bacteria,1VPEN@1239|Firmicutes,24AK1@186801|Clostridia	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS1_k127_13150739_2	247490.KSU1_B0459	3.475e-51	193.0	COG0363@1|root,COG0363@2|Bacteria,2J0I5@203682|Planctomycetes	203682|Planctomycetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS1_k127_13150739_0	1282876.BAOK01000002_gene529	3.471e-75	272.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,4BQEN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	nodT	-	-	ko:K18904	-	M00699	-	-	ko00000,ko00002,ko02000	1.B.17.3.8	-	-	OEP
GDHHQS1_k127_13150739_3	1210884.HG799464_gene10755	1.503e-28	123.0	COG1309@1|root,COG1309@2|Bacteria,2J08X@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
GDHHQS1_k127_13150739_5	1168034.FH5T_07240	6.713e-07	56.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3
GDHHQS1_k127_13153853_1	1123248.KB893385_gene4912	1.009e-154	493.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13153853_3	1210884.HG799463_gene9554	1.167e-68	241.0	COG2120@1|root,COG2120@2|Bacteria,2IYPC@203682|Planctomycetes	203682|Planctomycetes	S	LmbE homologs	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS1_k127_13153853_2	1403819.BATR01000191_gene6474	1.498e-134	437.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_13153853_0	313628.LNTAR_07649	2.341e-245	790.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,TAT_signal
GDHHQS1_k127_13158273_1	545695.TREAZ_2539	6.789e-30	134.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS1_k127_13158273_0	886293.Sinac_1805	3.719e-208	664.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS1_k127_13158273_2	1142394.PSMK_16190	4.199e-06	50.0	COG0736@1|root,COG0736@2|Bacteria,2IZSD@203682|Planctomycetes	203682|Planctomycetes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS1_k127_13246673_0	644968.DFW101_3675	4.396e-173	598.0	COG0438@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0859@2|Bacteria,1RFBZ@1224|Proteobacteria,43AIS@68525|delta/epsilon subdivisions,2WV3S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GDHHQS1_k127_13246673_3	207559.Dde_0429	1.266e-29	139.0	COG0500@1|root,COG1216@1|root,COG4627@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,COG4627@2|Bacteria,1N73D@1224|Proteobacteria,42XDU@68525|delta/epsilon subdivisions,2WRMM@28221|Deltaproteobacteria,2MD77@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_13246673_2	484770.UFO1_1091	3.488e-38	148.0	arCOG09486@1|root,32C6V@2|Bacteria,1U5Q8@1239|Firmicutes,4H8BZ@909932|Negativicutes	909932|Negativicutes	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
GDHHQS1_k127_13309686_2	761193.Runsl_2743	1.258e-133	435.0	COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes,47N67@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13309686_3	472759.Nhal_3295	4.523e-90	309.0	COG1680@1|root,COG1680@2|Bacteria,1NPBV@1224|Proteobacteria,1SQWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Domain of unknown function (DUF4185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
GDHHQS1_k127_13309686_1	344747.PM8797T_31193	3.433e-145	473.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_13309686_0	243090.RB4667	9.019e-146	475.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13309686_4	756272.Plabr_4562	3.944e-55	200.0	COG2755@1|root,COG2755@2|Bacteria,2IZUU@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GDHHQS1_k127_13314812_1	675635.Psed_3035	2.563e-165	530.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4E8N2@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	pcaJ	-	2.8.3.5,2.8.3.6	ko:K01027,ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS1_k127_13314812_0	1244869.H261_15452	1.821e-234	747.0	COG0664@1|root,COG1235@1|root,COG2703@1|root,COG0664@2|Bacteria,COG1235@2|Bacteria,COG2703@2|Bacteria,1R90N@1224|Proteobacteria,2TTTI@28211|Alphaproteobacteria,2JVDD@204441|Rhodospirillales	204441|Rhodospirillales	PT	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B_2,cNMP_binding
GDHHQS1_k127_13314812_2	1085623.GNIT_0162	7.303e-11	63.0	2EU5D@1|root,33MN1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13343403_1	344747.PM8797T_16882	1.535e-33	151.0	COG2982@1|root,COG2982@2|Bacteria,2IYVI@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
GDHHQS1_k127_13343403_0	861299.J421_5620	1.073e-62	225.0	28J3W@1|root,2Z900@2|Bacteria	2|Bacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
GDHHQS1_k127_13343403_2	1123487.KB892844_gene824	8.048e-28	128.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2VWQW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
GDHHQS1_k127_13363071_2	945713.IALB_1809	5.006e-97	323.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
GDHHQS1_k127_13363071_1	525904.Tter_1322	1.14e-113	376.0	COG0667@1|root,COG0667@2|Bacteria,2NPI2@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_13363071_0	471854.Dfer_1256	4.268e-270	853.0	COG3250@1|root,COG3250@2|Bacteria,4PN2B@976|Bacteroidetes,47Y68@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_2_N
GDHHQS1_k127_13363071_3	344747.PM8797T_11294	6.97e-42	166.0	COG1183@1|root,COG1183@2|Bacteria,2IZHR@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_13376265_0	1142394.PSMK_11810	2.173e-92	318.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
GDHHQS1_k127_13376265_1	555088.DealDRAFT_0914	7.886e-15	81.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia	186801|Clostridia	O	Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GDHHQS1_k127_13376265_2	203119.Cthe_0857	5.986e-09	59.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia	186801|Clostridia	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
GDHHQS1_k127_13434685_4	90814.KL370891_gene982	7.919e-13	71.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1S7G4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS1_k127_13434685_1	479436.Vpar_1425	1.087e-69	246.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS1_k127_13434685_5	36875.HQ29_09160	3.026e-09	68.0	COG1333@1|root,COG1333@2|Bacteria,4NGT1@976|Bacteroidetes,2FQQR@200643|Bacteroidia,22WM7@171551|Porphyromonadaceae	976|Bacteroidetes	O	ResB-like family	ccs1	-	-	-	-	-	-	-	-	-	-	-	ResB
GDHHQS1_k127_13434685_3	290397.Adeh_0813	6.9e-35	143.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS1_k127_13434685_0	1121439.dsat_0488	3.942e-245	762.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria,2MASI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13434685_2	661478.OP10G_0540	1.078e-66	237.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
GDHHQS1_k127_13447483_1	525904.Tter_2595	6.209e-58	217.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS1_k127_13447483_0	335543.Sfum_1838	3.245e-296	925.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2MQ64@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GDHHQS1_k127_13541212_1	1123070.KB899247_gene1435	3.18e-221	701.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase,SASA
GDHHQS1_k127_13541212_0	886293.Sinac_5964	3.506e-306	955.0	COG5029@1|root,COG5029@2|Bacteria,2J2JG@203682|Planctomycetes	203682|Planctomycetes	O	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GDHHQS1_k127_13600918_1	660470.Theba_1003	7.33e-22	96.0	COG1032@1|root,COG1032@2|Bacteria,2GCAG@200918|Thermotogae	200918|Thermotogae	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
GDHHQS1_k127_13600918_3	1303518.CCALI_01803	8.384e-15	84.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_13600918_2	1303518.CCALI_02638	9.786e-16	87.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_13600918_0	861299.J421_5839	2.86e-24	113.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS1_k127_13612961_3	1142394.PSMK_16420	1.535e-42	157.0	COG0234@1|root,COG0234@2|Bacteria,2IZTF@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS1_k127_13612961_1	880073.Calab_0179	4.848e-98	329.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS1_k127_13612961_0	530564.Psta_2678	6.99e-134	447.0	COG4992@1|root,COG4992@2|Bacteria,2IWTF@203682|Planctomycetes	203682|Planctomycetes	E	COG4992 Ornithine acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_13612961_2	1142394.PSMK_14720	1.008e-95	323.0	COG0548@1|root,COG0548@2|Bacteria,2IWVV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS1_k127_13686248_0	880072.Desac_0797	5.686e-32	130.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MS2E@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
GDHHQS1_k127_13686248_4	247490.KSU1_B0624	7.258e-05	52.0	COG4970@1|root,COG4970@2|Bacteria,2J478@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS1_k127_13686248_3	674977.VMC_02780	2.139e-10	70.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1XU01@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
GDHHQS1_k127_13686248_1	344747.PM8797T_14294	7.891e-31	138.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
GDHHQS1_k127_13686248_2	1123487.KB892863_gene1825	4.39e-18	95.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria,2KVIF@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG1450 Type II secretory pathway, component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
GDHHQS1_k127_13707263_0	96561.Dole_2278	1.716e-192	621.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMIR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
GDHHQS1_k127_13707263_2	96561.Dole_2279	2.056e-35	142.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,2MM4X@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
GDHHQS1_k127_13707263_1	1403819.BATR01000069_gene2031	2.744e-37	161.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13746893_1	338966.Ppro_2693	5.434e-42	163.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS1_k127_13746893_0	1396418.BATQ01000117_gene4549	5.169e-65	235.0	COG1477@1|root,COG1477@2|Bacteria,46VJI@74201|Verrucomicrobia,2IW89@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ApbE family	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
GDHHQS1_k127_13746893_2	240016.ABIZ01000001_gene2631	1.09e-35	147.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_13827269_1	1142394.PSMK_11820	2.078e-86	295.0	COG2019@1|root,COG2019@2|Bacteria	2|Bacteria	F	adenylate kinase activity	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
GDHHQS1_k127_13827269_0	237368.SCABRO_02763	8.103e-109	364.0	COG0216@1|root,COG0216@2|Bacteria,2IY77@203682|Planctomycetes	203682|Planctomycetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS1_k127_13827269_3	1125863.JAFN01000001_gene1727	5.837e-26	109.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS1_k127_13827269_2	247490.KSU1_C1120	3.899e-71	250.0	COG0289@1|root,COG0289@2|Bacteria,2IX9G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GDHHQS1_k127_13830011_0	522772.Dacet_2325	4.67e-156	503.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS1_k127_13830011_1	1392488.JHZY01000004_gene1984	6.285e-07	62.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,Calx-beta,LTD,PKD,SLH
GDHHQS1_k127_13852347_4	1209989.TepiRe1_2042	6.918e-51	187.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,42G76@68295|Thermoanaerobacterales	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS1_k127_13852347_3	552811.Dehly_0927	5.869e-72	255.0	COG0543@1|root,COG2204@1|root,COG0543@2|Bacteria,COG2204@2|Bacteria,2G7HU@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GDHHQS1_k127_13852347_1	880073.Calab_0418	4.452e-88	298.0	COG0543@1|root,COG0543@2|Bacteria,2NPFH@2323|unclassified Bacteria	2|Bacteria	CH	Oxidoreductase NAD-binding domain	asrB	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K02823,ko:K16951	ko00240,ko00920,ko01100,ko01120,map00240,map00920,map01100,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12555	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GDHHQS1_k127_13852347_2	237368.SCABRO_02488	1.096e-79	273.0	COG1941@1|root,COG1941@2|Bacteria,2IXWB@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
GDHHQS1_k127_13852347_0	1121440.AUMA01000003_gene2888	7.214e-138	451.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42RHV@68525|delta/epsilon subdivisions,2WNH5@28221|Deltaproteobacteria,2MA5W@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	hyhL	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
GDHHQS1_k127_13856687_5	1210884.HG799469_gene14193	4.03e-06	57.0	2BVUN@1|root,33C49@2|Bacteria,2J1P8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
GDHHQS1_k127_13856687_0	1278307.KB906973_gene1343	6.211e-172	561.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,1T0KQ@1236|Gammaproteobacteria,2QHBY@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
GDHHQS1_k127_13856687_1	1278307.KB906973_gene1350	7.181e-145	474.0	COG1541@1|root,COG1541@2|Bacteria,1QA98@1224|Proteobacteria,1T9JJ@1236|Gammaproteobacteria,2QI3N@267894|Psychromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS1_k127_13856687_2	204669.Acid345_3796	3.054e-121	406.0	COG2006@1|root,COG2006@2|Bacteria,3Y7YQ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS1_k127_13856687_3	314282.PCNPT3_01395	9.83e-85	298.0	COG0438@1|root,COG0438@2|Bacteria,1RBPW@1224|Proteobacteria,1SET3@1236|Gammaproteobacteria,2QI46@267894|Psychromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_13856687_4	357804.Ping_0439	5.017e-45	169.0	COG0726@1|root,COG0726@2|Bacteria,1P78Y@1224|Proteobacteria,1TDBB@1236|Gammaproteobacteria,2QHKN@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13894439_5	143224.JQMD01000002_gene65	7.948e-05	54.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes,1HZYK@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
GDHHQS1_k127_13894439_0	314230.DSM3645_22636	1.122e-184	587.0	COG0439@1|root,COG0439@2|Bacteria,2IWZV@203682|Planctomycetes	203682|Planctomycetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS1_k127_13894439_1	382464.ABSI01000011_gene2581	8.258e-30	126.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,2IUDK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS1_k127_13894439_3	368407.Memar_2196	1.454e-06	55.0	arCOG06881@1|root,arCOG06881@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13894439_4	1247726.MIM_c36370	5.387e-06	54.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,3T95I@506|Alcaligenaceae	28216|Betaproteobacteria	K	Rrf2 family transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
GDHHQS1_k127_13894439_2	313628.LNTAR_12566	8.672e-15	86.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GDHHQS1_k127_13906065_0	1379270.AUXF01000001_gene2607	3.082e-40	162.0	COG1408@1|root,COG1408@2|Bacteria,1ZV9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
GDHHQS1_k127_13906065_1	456442.Mboo_1398	1.157e-19	89.0	COG1145@1|root,arCOG04117@2157|Archaea,2Y7JN@28890|Euryarchaeota,2NBK8@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
GDHHQS1_k127_13940803_0	330214.NIDE2673	6.763e-73	257.0	COG0609@1|root,COG0609@2|Bacteria,3J11Y@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS1_k127_13940803_1	767817.Desgi_2382	3.383e-54	200.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,261YH@186807|Peptococcaceae	186801|Clostridia	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS1_k127_13940803_2	247490.KSU1_D0651	5.699e-28	118.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
GDHHQS1_k127_13959562_1	518766.Rmar_1740	1.887e-87	301.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_13959562_0	313628.LNTAR_11346	1.28e-202	646.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_13959562_2	644548.SCNU_04986	7.138e-25	115.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4GBAX@85026|Gordoniaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
GDHHQS1_k127_13959562_3	525897.Dbac_2370	2.805e-21	94.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2M8WG@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS1_k127_13961668_1	1121904.ARBP01000025_gene6085	1.25e-23	108.0	COG2273@1|root,COG2730@1|root,COG3291@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	chiA	-	3.2.1.4,3.2.1.73,3.2.1.80	ko:K01179,ko:K01216,ko:K03332,ko:K20276	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R00879,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM_6,CHU_C,F5_F8_type_C,Glyco_hydro_16,PKD
GDHHQS1_k127_13961668_2	1121887.AUDK01000020_gene2403	1.087e-18	102.0	COG4733@1|root,COG4733@2|Bacteria,4PPKU@976|Bacteroidetes,1I62W@117743|Flavobacteriia,2NZZ1@237|Flavobacterium	976|Bacteroidetes	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS1_k127_13961668_0	1396141.BATP01000018_gene1531	6.939e-27	128.0	COG2133@1|root,COG2755@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,46VBR@74201|Verrucomicrobia,2IUWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF1800,DUF5011,PA14
GDHHQS1_k127_13961668_3	376686.Fjoh_4098	3.067e-11	77.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia,2NTFA@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_13980719_1	1142394.PSMK_03840	8.058e-25	106.0	COG0592@1|root,COG0592@2|Bacteria,2IY9S@203682|Planctomycetes	203682|Planctomycetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GDHHQS1_k127_13980719_0	398767.Glov_0004	5.786e-224	720.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS1_k127_14000673_2	886293.Sinac_4705	1.633e-12	72.0	COG2834@1|root,COG2834@2|Bacteria,2J4MG@203682|Planctomycetes	203682|Planctomycetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_14000673_1	397291.C804_06320	9.637e-45	174.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	CP_0058	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_14000673_3	99598.Cal7507_2885	5.888e-11	72.0	28TQV@1|root,2ZFY2@2|Bacteria	2|Bacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_14000673_0	344747.PM8797T_10979	1.572e-55	200.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_14039379_3	1346791.M529_03980	2.812e-14	84.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS1_k127_14039379_2	530564.Psta_0855	4.248e-60	220.0	COG1082@1|root,COG1082@2|Bacteria,2J52H@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_14039379_1	234267.Acid_1241	2.959e-71	259.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	MA20_44000	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_14039379_0	1122214.AQWH01000003_gene3900	7.131e-98	336.0	COG3119@1|root,COG3119@2|Bacteria,1NTUU@1224|Proteobacteria,2UQWA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_14039379_4	575540.Isop_1803	2.391e-12	71.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS1_k127_14082300_2	1047013.AQSP01000092_gene326	2.595e-27	113.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
GDHHQS1_k127_14082300_1	521011.Mpal_2572	3.158e-66	234.0	COG4063@1|root,arCOG03221@2157|Archaea	2157|Archaea	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA-2	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
GDHHQS1_k127_14082300_4	573064.Mefer_1348	5.056e-23	107.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS1_k127_14082300_0	595460.RRSWK_03127	6.592e-166	532.0	COG0701@1|root,COG0701@2|Bacteria,2J0GE@203682|Planctomycetes	203682|Planctomycetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
GDHHQS1_k127_14082300_3	706587.Desti_5397	1.731e-25	109.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MSJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS1_k127_14305261_3	641524.ADICYQ_2828	1.353e-19	91.0	COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,47NDY@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS1_k127_14305261_0	1121875.KB907550_gene801	1.938e-109	373.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS1_k127_14305261_1	314230.DSM3645_20802	1.348e-57	220.0	COG1082@1|root,COG1082@2|Bacteria,2J52H@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_14305261_2	880070.Cycma_3663	5.563e-42	166.0	COG3119@1|root,COG3119@2|Bacteria,4NKU6@976|Bacteroidetes,47MJE@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_14313471_0	344747.PM8797T_19819	1.979e-172	554.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_14313471_3	1384056.N787_07285	4.033e-09	67.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,1X75M@135614|Xanthomonadales	135614|Xanthomonadales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GDHHQS1_k127_14313471_2	1157708.KB907457_gene2711	1.051e-95	323.0	COG1172@1|root,COG1172@2|Bacteria,1R4R3@1224|Proteobacteria,2VJTQ@28216|Betaproteobacteria,4ACW1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS1_k127_14313471_1	402626.Rpic_0881	9.413e-101	336.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VPAV@28216|Betaproteobacteria,1K04W@119060|Burkholderiaceae	28216|Betaproteobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GDHHQS1_k127_143394_0	1123242.JH636434_gene5289	7.959e-189	599.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_143394_1	555779.Dthio_PD3791	8.41e-41	154.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,42UNH@68525|delta/epsilon subdivisions,2WQQJ@28221|Deltaproteobacteria,2MCKW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GDHHQS1_k127_143394_4	1125863.JAFN01000001_gene2594	8.103e-20	91.0	COG4456@1|root,COG4456@2|Bacteria,1N7FM@1224|Proteobacteria,42VSD@68525|delta/epsilon subdivisions,2WSAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
GDHHQS1_k127_143394_3	386456.JQKN01000001_gene1893	1.416e-30	130.0	COG5012@1|root,arCOG03402@2157|Archaea	2157|Archaea	T	Cobalamin B12-binding domain protein	-	-	-	ko:K16955,ko:K22491	ko00920,map00920	-	R09997	RC00035	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2
GDHHQS1_k127_143394_2	713587.THITH_04690	1.5e-40	151.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,1SQ13@1236|Gammaproteobacteria,1X189@135613|Chromatiales	135613|Chromatiales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS1_k127_143394_5	247490.KSU1_C0546	5.17e-15	86.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,Metallophos,Pur_ac_phosph_N
GDHHQS1_k127_1435798_2	344747.PM8797T_05165	4.959e-59	218.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS1_k127_1435798_0	521674.Plim_3544	2.369e-107	355.0	COG0115@1|root,COG0115@2|Bacteria,2IY3N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS1_k127_1435798_1	530564.Psta_0644	3.164e-69	242.0	COG1136@1|root,COG1136@2|Bacteria,2IYZ3@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
GDHHQS1_k127_1435798_3	859653.HIMB5_00005600	1.176e-13	78.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,4BPKM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS1_k127_14422313_2	401526.TcarDRAFT_2406	6.902e-85	291.0	COG3804@1|root,COG3804@2|Bacteria,1TRNF@1239|Firmicutes,4H7KW@909932|Negativicutes	909932|Negativicutes	C	Dihydrodipicolinate reductase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DapB_N
GDHHQS1_k127_14422313_0	1121904.ARBP01000018_gene2704	1.208e-148	484.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS1_k127_14422313_1	1123508.JH636439_gene1628	7.884e-131	430.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_1447741_1	639283.Snov_0474	3.039e-25	109.0	COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2TV5U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Methyltransferase	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
GDHHQS1_k127_1447741_3	1178482.BJB45_08010	1.515e-13	79.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
GDHHQS1_k127_1447741_2	1122927.KB895414_gene5100	6.061e-23	100.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HWXY@91061|Bacilli,2704G@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS1_k127_1447741_0	309799.DICTH_0508	1.479e-70	242.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	iLJ478.TM1752	CBM_6,Cellulase
GDHHQS1_k127_1483580_1	251221.35213566	5.663e-26	120.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1483580_0	344747.PM8797T_02844	1.187e-271	863.0	COG3420@1|root,COG3420@2|Bacteria,2J2QH@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_1516460_0	1303518.CCALI_02122	1.287e-99	339.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1516460_1	290397.Adeh_1180	2.613e-92	312.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS1_k127_1611920_0	237368.SCABRO_03034	1.054e-42	159.0	COG1951@1|root,COG1951@2|Bacteria,2J2AN@203682|Planctomycetes	203682|Planctomycetes	C	Fumarate hydratase (Fumerase)	-	-	-	-	-	-	-	-	-	-	-	-	Fumerase
GDHHQS1_k127_1611920_2	661478.OP10G_0377	4.04e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_1611920_3	278957.ABEA03000157_gene620	2.025e-12	77.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS1_k127_1611920_1	661478.OP10G_3764	4.301e-19	98.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_1620566_0	575540.Isop_2722	4.929e-243	764.0	COG0480@1|root,COG0480@2|Bacteria,2IXUD@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS1_k127_170616_5	665571.STHERM_c19690	3.829e-45	168.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS1_k127_170616_4	880526.KE386488_gene1530	2.176e-55	195.0	COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,22U0B@171550|Rikenellaceae	976|Bacteroidetes	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
GDHHQS1_k127_170616_3	1122931.AUAE01000005_gene3388	3.826e-71	244.0	COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,22W1C@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
GDHHQS1_k127_170616_0	886379.AEWI01000026_gene438	1.489e-245	775.0	COG1208@1|root,COG1208@2|Bacteria,4NGYR@976|Bacteroidetes,2FMJ4@200643|Bacteroidia,3XJ22@558415|Marinilabiliaceae	976|Bacteroidetes	JM	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
GDHHQS1_k127_170616_6	344747.PM8797T_14204	0.0001166	52.0	COG3023@1|root,COG3023@2|Bacteria,2J0EH@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
GDHHQS1_k127_170616_1	240292.Ava_3911	2.122e-104	355.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1HJCQ@1161|Nostocales	1117|Cyanobacteria	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS1_k127_170616_2	344747.PM8797T_27040	2.857e-75	263.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_1760161_1	1453505.JASY01000003_gene2149	1.099e-06	60.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1760161_0	385682.AFSL01000034_gene2985	5.896e-195	629.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,2FM3X@200643|Bacteroidia,3XKS4@558415|Marinilabiliaceae	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_1789954_3	1248232.BANQ01000071_gene1664	4.244e-05	54.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1XSXC@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
GDHHQS1_k127_1789954_0	237368.SCABRO_02316	3.306e-141	469.0	COG0457@1|root,COG0457@2|Bacteria,2IYBQ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_1789954_2	1499967.BAYZ01000063_gene6022	1.222e-16	91.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
GDHHQS1_k127_1789954_1	56110.Oscil6304_3682	8.488e-25	108.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS1_k127_1808778_2	411464.DESPIG_02476	1.415e-44	168.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS1_k127_1808778_0	246194.CHY_1579	6.256e-222	706.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,42EQA@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS1_k127_1808778_3	1274.HX89_04600	2.259e-10	67.0	COG1716@1|root,COG1716@2|Bacteria,2HZE9@201174|Actinobacteria,1ZWVR@145357|Dermacoccaceae	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS1_k127_1808778_1	886293.Sinac_5248	1.152e-89	317.0	COG2804@1|root,COG2804@2|Bacteria,2IXVD@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
GDHHQS1_k127_1813613_3	1501230.ET33_00530	9.394e-59	210.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,26TD7@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
GDHHQS1_k127_1813613_1	189425.PGRAT_11470	6.187e-68	248.0	COG1032@1|root,COG1032@2|Bacteria,1V8ME@1239|Firmicutes,4HT2W@91061|Bacilli,276JW@186822|Paenibacillaceae	91061|Bacilli	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS1_k127_1813613_0	247490.KSU1_C0143	1.756e-149	487.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
GDHHQS1_k127_1813613_2	1304284.L21TH_1868	2.169e-60	224.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,36GR6@31979|Clostridiaceae	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GDHHQS1_k127_1832186_1	187272.Mlg_0289	4.689e-25	107.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1WX6X@135613|Chromatiales	135613|Chromatiales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_1832186_3	243233.MCA1292	9.58e-06	53.0	2DD9Q@1|root,2ZH70@2|Bacteria,1P8P5@1224|Proteobacteria,1SWFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1832186_0	667014.Thein_1217	2.761e-109	362.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_1832186_2	1047013.AQSP01000134_gene1374	1.338e-19	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
GDHHQS1_k127_1839107_0	237368.SCABRO_00615	1.088e-138	462.0	COG0826@1|root,COG0826@2|Bacteria,2J1YE@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
GDHHQS1_k127_1839107_2	247490.KSU1_D0381	4.204e-32	134.0	COG2945@1|root,COG2945@2|Bacteria,2J37A@203682|Planctomycetes	203682|Planctomycetes	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1839107_1	237368.SCABRO_00616	2.03e-90	312.0	COG0318@1|root,COG0318@2|Bacteria,2J4XH@203682|Planctomycetes	203682|Planctomycetes	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1839107_3	237368.SCABRO_00617	8.698e-08	55.0	COG1033@1|root,COG1033@2|Bacteria,2IYET@203682|Planctomycetes	203682|Planctomycetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
GDHHQS1_k127_1859308_1	316274.Haur_1388	2.801e-28	123.0	2BJH7@1|root,32UCG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1859308_0	314230.DSM3645_23496	6.752e-182	581.0	COG3119@1|root,COG3119@2|Bacteria,2IXP1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_1859308_2	397948.Cmaq_0229	1.704e-14	86.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1868581_2	1303518.CCALI_02122	3.894e-38	158.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1868581_0	143224.JQMD01000002_gene281	3.226e-193	614.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_1868581_1	1396418.BATQ01000088_gene1040	1.354e-126	411.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS1_k127_1884187_2	344747.PM8797T_32040	9.895e-84	287.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
GDHHQS1_k127_1884187_1	240016.ABIZ01000001_gene228	1.885e-131	429.0	COG1680@1|root,COG5297@1|root,COG1680@2|Bacteria,COG5297@2|Bacteria,46TK0@74201|Verrucomicrobia,2IVMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1593
GDHHQS1_k127_1884187_0	278957.ABEA03000041_gene2050	1.426e-151	502.0	COG5434@1|root,COG5434@2|Bacteria,46U2F@74201|Verrucomicrobia,3K9E5@414999|Opitutae	414999|Opitutae	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_190932_0	518766.Rmar_0491	6.001e-131	430.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJX9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_190932_1	394503.Ccel_0992	9.627e-78	273.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GDHHQS1_k127_194909_0	411469.EUBHAL_02285	4.096e-88	297.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,25V5V@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
GDHHQS1_k127_194909_1	1033736.CAHK01000033_gene1129	9.553e-17	91.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
GDHHQS1_k127_194909_2	1123226.KB899286_gene3522	2.082e-15	83.0	COG1595@1|root,COG1595@2|Bacteria,1V5UR@1239|Firmicutes,4IQ33@91061|Bacilli,2768T@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_1961002_3	1209072.ALBT01000033_gene1563	1.227e-31	131.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,1SYWK@1236|Gammaproteobacteria,1FH5M@10|Cellvibrio	1236|Gammaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
GDHHQS1_k127_1961002_1	1101195.Meth11DRAFT_2145	2.417e-44	169.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2VVR8@28216|Betaproteobacteria,2KP2K@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS1_k127_1961002_5	1166018.FAES_0711	2.181e-07	55.0	COG0110@1|root,COG0110@2|Bacteria,4NMHW@976|Bacteroidetes,47PBU@768503|Cytophagia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GDHHQS1_k127_1961002_2	1042377.AFPJ01000055_gene959	5.094e-39	155.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,465SE@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
GDHHQS1_k127_1961002_4	1469613.JT55_00690	7.673e-15	87.0	28M26@1|root,2ZAGS@2|Bacteria,1RB21@1224|Proteobacteria,2TYAM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS1_k127_1961002_0	56780.SYN_02391	4.975e-62	218.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase, family 2	MA20_09515	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
GDHHQS1_k127_1999082_1	504832.OCAR_7726	3.882e-75	259.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,3JRVP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
GDHHQS1_k127_1999082_2	443144.GM21_4072	1.509e-68	238.0	COG2890@1|root,COG2890@2|Bacteria,1R034@1224|Proteobacteria,43CQ7@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_1999082_0	1121405.dsmv_0645	2.469e-143	463.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2MHR8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS1_k127_1999082_3	381764.Fnod_1552	1.093e-06	61.0	COG1520@1|root,COG3291@1|root,COG5276@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG5276@2|Bacteria,2GDF3@200918|Thermotogae	200918|Thermotogae	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2029367_3	479434.Sthe_0853	1.602e-27	122.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XGX@189775|Thermomicrobia	189775|Thermomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_2029367_0	1280679.ATVX01000007_gene1400	3.444e-60	227.0	COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,25ERN@186801|Clostridia,4BZM9@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.348	ko:K06338,ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_2029367_2	748449.Halha_2399	1.773e-31	137.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_2029367_4	2325.TKV_c21370	1.201e-10	72.0	COG0500@1|root,COG2226@2|Bacteria,1UY28@1239|Firmicutes,24CTT@186801|Clostridia,42GDX@68295|Thermoanaerobacterales	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
GDHHQS1_k127_2029367_1	383372.Rcas_0756	1.55e-34	141.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181	ko:K00568,ko:K18827	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781,R10657,R10658	RC00002,RC00003,RC00078,RC00392,RC01895,RC03220	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS1_k127_2060456_5	1121423.JONT01000003_gene976	2.373e-09	67.0	COG2041@1|root,COG5337@1|root,COG2041@2|Bacteria,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
GDHHQS1_k127_2060456_3	344747.PM8797T_07664	9.302e-58	226.0	COG1305@1|root,COG1305@2|Bacteria,2IZUN@203682|Planctomycetes	203682|Planctomycetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GDHHQS1_k127_2060456_4	595460.RRSWK_03714	1.179e-47	188.0	COG1721@1|root,COG1721@2|Bacteria,2J13Q@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS1_k127_2060456_0	595460.RRSWK_03715	2.237e-116	383.0	COG0714@1|root,COG0714@2|Bacteria,2IX1F@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
GDHHQS1_k127_2060456_1	278957.ABEA03000202_gene4315	6.496e-115	383.0	2DB8U@1|root,2Z7SW@2|Bacteria,46ZAI@74201|Verrucomicrobia,3K92W@414999|Opitutae	414999|Opitutae	G	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
GDHHQS1_k127_2060456_2	153721.MYP_2283	2.635e-98	329.0	COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes,47NTN@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_2104557_1	443143.GM18_2495	6.537e-58	215.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS1_k127_2104557_0	760142.Hipma_0476	5.063e-149	491.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
GDHHQS1_k127_213100_3	192952.MM_1144	1.538e-18	96.0	COG5563@1|root,arCOG03499@1|root,arCOG03499@2157|Archaea,arCOG03501@2157|Archaea	2157|Archaea	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
GDHHQS1_k127_213100_1	344747.PM8797T_05435	2.177e-137	450.0	COG0322@1|root,COG0322@2|Bacteria,2IWVR@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
GDHHQS1_k127_213100_0	886293.Sinac_3249	0.0	1199.0	COG0209@1|root,COG0209@2|Bacteria,2IX3H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
GDHHQS1_k127_213100_4	595460.RRSWK_04237	2.154e-10	69.0	2EQFW@1|root,33I1X@2|Bacteria,2J1JM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_213100_5	309799.DICTH_0269	0.0005807	50.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	pfbA	-	-	ko:K13925	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,CW_binding_1,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3,YSIRK_signal
GDHHQS1_k127_213100_2	1121403.AUCV01000006_gene427	2.699e-52	192.0	2DUCW@1|root,33Q17@2|Bacteria	2|Bacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_2217450_0	1123288.SOV_6c02310	9.072e-102	338.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4H1ZY@909932|Negativicutes	909932|Negativicutes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS1_k127_2217450_2	1303518.CCALI_01913	2.985e-43	171.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_2217450_3	927658.AJUM01000007_gene2723	4.613e-38	160.0	COG5520@1|root,COG5520@2|Bacteria,4PIPI@976|Bacteroidetes,2G1E7@200643|Bacteroidia,3XKYS@558415|Marinilabiliaceae	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2217450_1	1191523.MROS_1709	4.15e-60	216.0	28PU4@1|root,2ZCF6@2|Bacteria	2|Bacteria	-	-	nrfJ	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2217450_5	886293.Sinac_6987	8.235e-05	46.0	COG1413@1|root,COG1413@2|Bacteria,2IX4C@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_2239610_4	856793.MICA_1866	7.72e-10	69.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,4BQP8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS1_k127_2239610_2	1142394.PSMK_14530	2.014e-148	477.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS1_k127_2239610_5	886293.Sinac_3049	0.0005241	49.0	COG3023@1|root,COG3023@2|Bacteria,2J0EH@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
GDHHQS1_k127_2239610_1	589865.DaAHT2_0197	3.636e-207	657.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MIH0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
GDHHQS1_k127_2239610_0	589865.DaAHT2_0196	2.823e-264	833.0	COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS1_k127_2239610_3	697303.Thewi_2114	1.096e-38	147.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS1_k127_2258493_2	1116375.VEJY3_23496	9.307e-24	102.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1S9KC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS1_k127_2258493_5	644282.Deba_2758	5.548e-06	51.0	2BFXK@1|root,329T8@2|Bacteria,1NIXU@1224|Proteobacteria,438SZ@68525|delta/epsilon subdivisions,2WY8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2258493_0	379066.GAU_1081	1.129e-77	274.0	COG0673@1|root,COG0673@2|Bacteria,1ZSVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_2258493_3	1157637.KB892097_gene1182	3.112e-14	78.0	COG1846@1|root,COG1846@2|Bacteria,2IFRN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS1_k127_2258493_1	552811.Dehly_1422	1.88e-67	241.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi,34CS0@301297|Dehalococcoidia	301297|Dehalococcoidia	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS1_k127_2258493_4	768710.DesyoDRAFT_1514	1.309e-10	65.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS1_k127_2315566_0	926550.CLDAP_30260	4.611e-84	310.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
GDHHQS1_k127_2329939_4	595460.RRSWK_05155	6.298e-06	53.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
GDHHQS1_k127_2329939_3	459349.CLOAM0984	4.384e-35	154.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
GDHHQS1_k127_2329939_2	761193.Runsl_2560	1.106e-102	342.0	COG3828@1|root,COG3828@2|Bacteria,4PNCT@976|Bacteroidetes,47NTF@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_2329939_0	761193.Runsl_2557	3.213e-147	478.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_2329939_1	761193.Runsl_3310	2.28e-125	415.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_2363204_2	794903.OPIT5_23075	1.23e-11	68.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_2363204_3	661478.OP10G_1071	1.098e-10	72.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_2363204_1	1121035.AUCH01000004_gene311	1.789e-18	96.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,2KUG9@206389|Rhodocyclales	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_2363204_0	237368.SCABRO_00310	4.513e-67	248.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS1_k127_2544201_1	1122931.AUAE01000007_gene1342	3.246e-61	222.0	COG0457@1|root,COG0457@2|Bacteria,4NKMF@976|Bacteroidetes,2FXC5@200643|Bacteroidia,231HD@171551|Porphyromonadaceae	1122931.AUAE01000007_gene1342|-	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2544201_0	720554.Clocl_3296	6.688e-110	372.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS1_k127_2544201_2	504487.JCM19302_1724	1.374e-31	126.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS1_k127_2544201_3	177437.HRM2_22520	1.954e-11	67.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MJ56@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS1_k127_2559914_0	1142394.PSMK_21970	2.134e-78	278.0	COG3693@1|root,COG3693@2|Bacteria,2IXI6@203682|Planctomycetes	203682|Planctomycetes	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
GDHHQS1_k127_2559914_3	1123502.AQXD01000001_gene1356	3.641e-05	51.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	ybaV	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.1.26.11	ko:K00784,ko:K02237	ko03013,map03013	M00429	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS1_k127_2559914_2	1123508.JH636443_gene4909	1.331e-20	98.0	2BWMY@1|root,331GB@2|Bacteria,2J0M4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2559914_1	1123508.JH636439_gene543	4.63e-76	269.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
GDHHQS1_k127_2562091_0	1396141.BATP01000034_gene4198	9.331e-190	634.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
GDHHQS1_k127_2589275_1	314230.DSM3645_09722	5.686e-181	578.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_2589275_0	583355.Caka_0369	2.459e-198	630.0	COG1874@1|root,COG1874@2|Bacteria,46Y46@74201|Verrucomicrobia,3K958@414999|Opitutae	414999|Opitutae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2651047_0	997346.HMPREF9374_2257	8.585e-141	467.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,27BPV@186824|Thermoactinomycetaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS1_k127_2651047_1	452637.Oter_0169	5.022e-62	217.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
GDHHQS1_k127_2657673_1	247490.KSU1_C0546	1.579e-28	135.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,Metallophos,Pur_ac_phosph_N
GDHHQS1_k127_2657673_0	1396141.BATP01000027_gene1160	2.399e-45	190.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_2657673_2	795359.TOPB45_0466	1.214e-12	72.0	COG0680@1|root,COG0680@2|Bacteria,2GHZS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
GDHHQS1_k127_2749582_2	497964.CfE428DRAFT_3599	2.649e-16	83.0	COG3828@1|root,COG3828@2|Bacteria,46SK4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS1_k127_2749582_3	584708.Apau_2309	1.642e-11	78.0	COG3210@1|root,COG3210@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_2749582_0	671143.DAMO_2514	5.965e-53	192.0	COG4914@1|root,COG4914@2|Bacteria,2NR4D@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS1_k127_2749582_1	1131814.JAFO01000001_gene2573	5.707e-49	179.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
GDHHQS1_k127_2749582_4	397291.C804_02906	1.872e-05	47.0	COG1028@1|root,COG1028@2|Bacteria,1TQ3V@1239|Firmicutes,24ARQ@186801|Clostridia,27JV0@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS1_k127_2768497_1	1229276.DI53_3046	6.34e-30	122.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1IPZV@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
GDHHQS1_k127_2768497_0	1396141.BATP01000027_gene1160	7.604e-55	221.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_2768497_2	1122609.AUGT01000008_gene2868	2.497e-22	114.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
GDHHQS1_k127_2801871_1	1125863.JAFN01000001_gene3450	2.642e-162	517.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS1_k127_2801871_0	251229.Chro_2571	3.137e-203	644.0	COG2730@1|root,COG2730@2|Bacteria,1GRHI@1117|Cyanobacteria,3VM2P@52604|Pleurocapsales	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
GDHHQS1_k127_2801871_2	63737.Npun_R3915	2.247e-59	214.0	COG3374@1|root,COG3374@2|Bacteria,1G545@1117|Cyanobacteria,1HRAR@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF981)	-	-	-	ko:K08980	-	-	-	-	ko00000	-	-	-	DUF981
GDHHQS1_k127_2801871_3	414684.RC1_1730	1.689e-14	74.0	COG3335@1|root,COG3335@2|Bacteria,1RDBN@1224|Proteobacteria,2VFA9@28211|Alphaproteobacteria,2JYKU@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase and inactivated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS1_k127_285839_1	237368.SCABRO_03345	5.093e-148	481.0	COG1456@1|root,COG1456@2|Bacteria,2J2CN@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,FeS
GDHHQS1_k127_285839_0	247490.KSU1_D0223	7.77e-198	635.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2J2QB@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
GDHHQS1_k127_285839_4	247490.KSU1_D0222	4.022e-62	222.0	COG3640@1|root,COG3640@2|Bacteria,2J1XH@203682|Planctomycetes	203682|Planctomycetes	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_285839_2	247490.KSU1_D0221	9.351e-136	438.0	COG2069@1|root,COG2069@2|Bacteria,2J2KV@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD
GDHHQS1_k127_285839_3	237368.SCABRO_03350	8.058e-86	292.0	COG1410@1|root,COG1410@2|Bacteria,2IY5P@203682|Planctomycetes	203682|Planctomycetes	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS1_k127_285839_5	1200557.JHWV01000001_gene426	1.044e-33	133.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H2SQ@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GDHHQS1_k127_2895285_2	316067.Geob_2951	4.609e-72	247.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,43UQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS1_k127_2895285_0	1009370.ALO_13804	5.109e-106	360.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H2ZB@909932|Negativicutes	909932|Negativicutes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_2895285_1	933262.AXAM01000037_gene877	2.781e-79	279.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2WPER@28221|Deltaproteobacteria,2MM4H@213118|Desulfobacterales	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2895285_4	633149.Bresu_0057	3.792e-15	87.0	2EP9F@1|root,33GW6@2|Bacteria,1NM4Z@1224|Proteobacteria,2UXV0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2895285_3	608506.COB47_0230	3.213e-15	87.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,42FUY@68295|Thermoanaerobacterales	186801|Clostridia	M	alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
GDHHQS1_k127_2903161_1	247490.KSU1_D0224	1.8e-37	143.0	COG1456@1|root,COG1456@2|Bacteria,2J2CN@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,FeS
GDHHQS1_k127_2903161_0	247490.KSU1_D0226	1.369e-217	684.0	COG1614@1|root,COG1614@2|Bacteria,2J26P@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhC
GDHHQS1_k127_2909982_3	1123508.JH636439_gene697	4.768e-52	185.0	COG1117@1|root,COG1117@2|Bacteria,2IWRV@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS1_k127_2909982_2	1167006.UWK_01012	7.496e-70	245.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MICR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS1_k127_2909982_1	706587.Desti_5065	3.584e-91	305.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_2909982_0	1232410.KI421421_gene3404	7.377e-174	563.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43SD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
GDHHQS1_k127_2930082_0	1499967.BAYZ01000161_gene390	1.97e-231	733.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2NNXD@2323|unclassified Bacteria	2|Bacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,HSDR_N,N6_Mtase,TaqI_C
GDHHQS1_k127_2930082_1	1304885.AUEY01000012_gene1826	6.064e-32	128.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS1_k127_2930082_2	1303518.CCALI_00382	3.954e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
GDHHQS1_k127_2945411_4	886293.Sinac_7534	7.685e-32	133.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2945411_7	69279.BG36_16285	2.376e-11	75.0	COG0673@1|root,COG0673@2|Bacteria,1PE0Y@1224|Proteobacteria,2V8CR@28211|Alphaproteobacteria,43QAI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_2945411_1	314230.DSM3645_20407	1.295e-151	505.0	COG0557@1|root,COG0557@2|Bacteria,2IX1J@203682|Planctomycetes	203682|Planctomycetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS1_k127_2945411_3	373903.Hore_06150	1.449e-47	176.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WAPV@53433|Halanaerobiales	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS1_k127_2945411_0	886293.Sinac_5180	1.935e-285	915.0	COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS1_k127_2945411_6	1120973.AQXL01000037_gene601	2.631e-13	74.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061,ko:K07075	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
GDHHQS1_k127_2945411_5	760568.Desku_0700	8.579e-23	102.0	COG1895@1|root,COG1895@2|Bacteria,1U5TF@1239|Firmicutes,2512S@186801|Clostridia,266IR@186807|Peptococcaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_2945411_2	583355.Caka_1113	3.759e-56	203.0	2ERTX@1|root,33JD4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_2958859_2	373994.Riv7116_5468	1.878e-23	103.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	pspE	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
GDHHQS1_k127_2958859_3	1382356.JQMP01000004_gene419	8.453e-15	78.0	COG1872@1|root,COG1872@2|Bacteria,2G9SM@200795|Chloroflexi,27YQ3@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS1_k127_2958859_1	706587.Desti_3299	1.323e-49	194.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GDHHQS1_k127_2958859_0	1123242.JH636436_gene156	7.444e-58	208.0	2AU2S@1|root,31JP5@2|Bacteria,2IZEE@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_3027657_3	192952.MM_3111	2.915e-07	61.0	arCOG06867@1|root,arCOG06867@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3027657_2	913865.DOT_5802	1.374e-23	107.0	2E41I@1|root,33BYF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3027657_1	59931.WH7805_04656	2.477e-69	245.0	COG0142@1|root,COG0142@2|Bacteria,1G1H4@1117|Cyanobacteria,1GZHB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS1_k127_3027657_0	1304880.JAGB01000001_gene246	2.749e-78	271.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS1_k127_3055982_3	641524.ADICYQ_3694	8.232e-27	111.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS1_k127_3055982_0	1158294.JOMI01000004_gene3543	5.82e-96	333.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,2FSDK@200643|Bacteroidia	976|Bacteroidetes	G	SMP-30 Gluconolaconase LRE-like	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
GDHHQS1_k127_3055982_1	1499967.BAYZ01000095_gene4075	2.126e-93	325.0	COG2220@1|root,COG2220@2|Bacteria,2NQD1@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS1_k127_3055982_2	338963.Pcar_1342	5.08e-39	152.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS1_k127_3059939_3	41431.PCC8801_0045	0.0003376	52.0	COG0438@1|root,COG0438@2|Bacteria,1G1VE@1117|Cyanobacteria,3KIAJ@43988|Cyanothece	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
GDHHQS1_k127_3059939_2	247490.KSU1_D0540	4.159e-23	104.0	2EDD9@1|root,3379K@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3568
GDHHQS1_k127_3059939_1	255470.cbdbA1323	2.25e-44	171.0	COG0655@1|root,COG0655@2|Bacteria,2GAKP@200795|Chloroflexi,34CPA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS1_k127_3059939_0	292459.STH605	9.803e-50	183.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS1_k127_3138442_3	1297742.A176_06699	0.0001873	50.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
GDHHQS1_k127_3138442_2	224324.aq_418	4.292e-28	118.0	COG2165@1|root,COG2165@2|Bacteria,2G43Q@200783|Aquificae	200783|Aquificae	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
GDHHQS1_k127_3138442_1	502025.Hoch_2610	2.728e-71	256.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
GDHHQS1_k127_3138442_0	868864.Dester_0385	1.84e-122	400.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_3163975_1	700508.D174_24375	2.265e-36	153.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,232NK@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_3163975_0	755732.Fluta_2169	3.396e-46	180.0	COG0438@1|root,COG0438@2|Bacteria,4NU4C@976|Bacteroidetes,1I610@117743|Flavobacteriia,2PC3C@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
GDHHQS1_k127_3171899_1	1121335.Clst_0909	2.708e-28	120.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia,3WI0S@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	3.2.1.67	ko:K01213	ko00040,ko01100,map00040,map01100	M00081	R01982,R07413	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Pectate_lyase_3
GDHHQS1_k127_3171899_0	452637.Oter_2946	2.601e-64	241.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Collagen_bind_2,DUF4038,DUF5060,DUF721
GDHHQS1_k127_321165_0	344747.PM8797T_32040	9.662e-229	743.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
GDHHQS1_k127_321165_2	344747.PM8797T_31643	1.231e-63	224.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran
GDHHQS1_k127_321165_1	313628.LNTAR_12256	2.168e-96	329.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	tagS	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_3253002_2	717231.Flexsi_2006	4.22e-57	214.0	COG3005@1|root,COG3005@2|Bacteria,2GENG@200930|Deferribacteres	200930|Deferribacteres	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_3253002_1	1167006.UWK_00559	1.456e-62	228.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,42XKG@68525|delta/epsilon subdivisions,2WSNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS1_k127_3253002_5	1167006.UWK_00558	3.762e-37	152.0	COG2864@1|root,COG2864@2|Bacteria,1PAKU@1224|Proteobacteria	1224|Proteobacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3253002_3	589865.DaAHT2_2115	6.401e-45	184.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GDHHQS1_k127_3253002_0	1167006.UWK_00556	1.301e-92	328.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
GDHHQS1_k127_3253002_4	667014.Thein_0390	9.204e-38	154.0	COG3043@1|root,COG3043@2|Bacteria	2|Bacteria	C	anaerobic respiration	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_3257653_3	1537915.JU57_04990	4.293e-07	59.0	COG0484@1|root,COG0484@2|Bacteria,1MV51@1224|Proteobacteria,42MQ7@68525|delta/epsilon subdivisions,2YN07@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process	mccA	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554
GDHHQS1_k127_3257653_4	1123376.AUIU01000014_gene705	0.0001787	53.0	COG1333@1|root,COG1333@2|Bacteria,3J0N7@40117|Nitrospirae	40117|Nitrospirae	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
GDHHQS1_k127_3257653_0	1125863.JAFN01000001_gene977	7.581e-127	420.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_3257653_2	1125863.JAFN01000001_gene976	1.735e-22	111.0	COG0457@1|root,COG0457@2|Bacteria	1125863.JAFN01000001_gene976|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3257653_1	880073.Calab_1267	4.403e-32	133.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Paired_CXXCH_1
GDHHQS1_k127_3262626_0	1047013.AQSP01000126_gene2738	1.092e-132	429.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
GDHHQS1_k127_3262626_1	344747.PM8797T_31193	4.141e-126	416.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_3262626_3	1403819.BATR01000131_gene4677	1.091e-64	233.0	28IP5@1|root,2Z8P7@2|Bacteria	2|Bacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_3262626_2	504472.Slin_4997	1.056e-86	297.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_3276006_2	886293.Sinac_6338	2.045e-89	304.0	COG1207@1|root,COG1207@2|Bacteria,2IXXB@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
GDHHQS1_k127_3276006_1	247490.KSU1_B0544	1.376e-116	383.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS1_k127_3276006_5	237368.SCABRO_01904	9.523e-37	147.0	COG1825@1|root,COG1825@2|Bacteria,2J050@203682|Planctomycetes	203682|Planctomycetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS1_k127_3276006_3	485916.Dtox_0209	5.606e-49	181.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,261YC@186807|Peptococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS1_k127_3276006_7	575540.Isop_2891	9.754e-18	89.0	COG0360@1|root,COG0360@2|Bacteria,2J0U0@203682|Planctomycetes	203682|Planctomycetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS1_k127_3276006_4	237368.SCABRO_01907	4.913e-44	164.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS1_k127_3276006_8	867903.ThesuDRAFT_00492	2.204e-14	75.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3WCKW@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS1_k127_3276006_6	1121428.DESHY_30040___1	5.772e-25	109.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,26287@186807|Peptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS1_k127_3276006_0	1121396.KB893068_gene1425	6.293e-147	473.0	COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria,2MMRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3297745_2	313606.M23134_03995	1.417e-31	130.0	COG1451@1|root,COG1451@2|Bacteria,4NNY6@976|Bacteroidetes,47QZY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GDHHQS1_k127_3297745_1	1298865.H978DRAFT_0141	9.322e-81	289.0	COG3119@1|root,COG3119@2|Bacteria,1MWJ2@1224|Proteobacteria,1RXXA@1236|Gammaproteobacteria,46A1R@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_3297745_0	530564.Psta_2420	1.26e-90	313.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_3317307_5	756272.Plabr_2071	5.237e-13	68.0	COG0097@1|root,COG0097@2|Bacteria,2IZ8X@203682|Planctomycetes	203682|Planctomycetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GDHHQS1_k127_3317307_3	1231241.Mc24_04245	4.248e-35	137.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
GDHHQS1_k127_3317307_1	575540.Isop_2097	1.224e-51	188.0	COG0098@1|root,COG0098@2|Bacteria,2IZ7J@203682|Planctomycetes	203682|Planctomycetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GDHHQS1_k127_3317307_2	748449.Halha_0207	1.264e-36	143.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WARV@53433|Halanaerobiales	186801|Clostridia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GDHHQS1_k127_3317307_0	1142394.PSMK_28990	3.964e-142	464.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS1_k127_3317307_4	457415.HMPREF1006_01629	9.998e-32	126.0	COG0563@1|root,COG0563@2|Bacteria,3TA8N@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GDHHQS1_k127_3361645_1	1142394.PSMK_18480	1.828e-33	139.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS1_k127_3361645_3	247490.KSU1_B0095	2.204e-25	115.0	COG1360@1|root,COG1360@2|Bacteria,2IZSF@203682|Planctomycetes	203682|Planctomycetes	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS1_k127_3361645_0	1120953.AUBH01000006_gene2643	4.661e-101	345.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,46AI8@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS1_k127_3361645_2	247490.KSU1_D0074	5.279e-32	139.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2IY17@203682|Planctomycetes	203682|Planctomycetes	S	competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS1_k127_3384709_1	479435.Kfla_1584	1.311e-81	284.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,4DPTJ@85009|Propionibacteriales	201174|Actinobacteria	M	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS1_k127_3384709_0	1125863.JAFN01000001_gene389	4.869e-129	427.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS1_k127_3384709_2	1094508.Tsac_1460	6.983e-51	186.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
GDHHQS1_k127_3475209_0	1131462.DCF50_p1172	6.518e-204	646.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,2612Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
GDHHQS1_k127_3475209_1	1123248.KB893359_gene2154	1.302e-95	321.0	COG0726@1|root,COG0726@2|Bacteria,4NJK7@976|Bacteroidetes	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS1_k127_3475209_2	1121859.KB890739_gene2670	3.407e-18	96.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_3475209_3	927658.AJUM01000042_gene1500	5.665e-07	55.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565,SLH
GDHHQS1_k127_3480728_0	338966.Ppro_1051	5.07e-276	856.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS1_k127_3480728_2	1245475.ANAE01000179_gene1253	2.123e-37	146.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EQ8P@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS1_k127_3480728_3	1280689.AUJC01000007_gene3137	9.765e-10	68.0	2ETI9@1|root,32GER@2|Bacteria,1UE7C@1239|Firmicutes,25P08@186801|Clostridia,36T99@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3480728_1	1142394.PSMK_29610	1.142e-64	231.0	COG1234@1|root,COG1234@2|Bacteria,2IWSW@203682|Planctomycetes	203682|Planctomycetes	S	of the beta-lactamase	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS1_k127_3485868_1	1121403.AUCV01000002_gene470	5.021e-121	405.0	COG0543@1|root,COG1034@1|root,COG3383@1|root,COG0543@2|Bacteria,COG1034@2|Bacteria,COG3383@2|Bacteria,1P8MN@1224|Proteobacteria	1224|Proteobacteria	C	NADH-quinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GDHHQS1_k127_3485868_0	386456.JQKN01000009_gene1128	1.981e-236	747.0	COG1894@1|root,COG2221@1|root,arCOG02059@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GDHHQS1_k127_3485868_2	909663.KI867150_gene401	3.343e-43	162.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MQIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS1_k127_351545_0	143224.JQMD01000002_gene3089	6.356e-09	67.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,1I13Y@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_351545_1	234267.Acid_6615	5.729e-07	58.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3515823_1	439235.Dalk_3108	3.988e-68	239.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,43BDR@68525|delta/epsilon subdivisions,2X6SB@28221|Deltaproteobacteria,2MPIC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS1_k127_3515823_2	485916.Dtox_3914	2.866e-31	131.0	COG2401@1|root,COG2401@2|Bacteria,1VR03@1239|Firmicutes,24ZUD@186801|Clostridia,264JV@186807|Peptococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS1_k127_3515823_3	370438.PTH_2198	4.476e-17	92.0	COG2401@1|root,COG2401@2|Bacteria,1VR03@1239|Firmicutes,24ZUD@186801|Clostridia,264JV@186807|Peptococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS1_k127_3515823_5	264203.ZMO1978	2.297e-11	73.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2K0RQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS1_k127_3515823_4	457570.Nther_0049	1.472e-11	70.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3515823_0	756272.Plabr_2744	1.121e-140	452.0	COG3119@1|root,COG3119@2|Bacteria,2IYNZ@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_353170_1	926566.Terro_2076	4.572e-51	191.0	COG2309@1|root,COG2309@2|Bacteria,3Y46T@57723|Acidobacteria,2JKPZ@204432|Acidobacteriia	204432|Acidobacteriia	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
GDHHQS1_k127_353170_0	927658.AJUM01000022_gene1031	2.935e-189	595.0	COG0524@1|root,COG0524@2|Bacteria,4NH8K@976|Bacteroidetes,2FM8P@200643|Bacteroidia,3XIZT@558415|Marinilabiliaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS1_k127_353170_2	641524.ADICYQ_3002	7.487e-39	161.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,47VT1@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS1_k127_3595873_2	1291050.JAGE01000001_gene363	6.087e-76	260.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS1_k127_3595873_1	1077285.AGDG01000002_gene2066	1.659e-99	339.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,2FQW5@200643|Bacteroidia,4AN9D@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
GDHHQS1_k127_3595873_3	583355.Caka_0200	9.024e-68	239.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
GDHHQS1_k127_3595873_0	247490.KSU1_D0789	1.011e-106	362.0	COG0771@1|root,COG0771@2|Bacteria,2IX53@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_3595873_4	756272.Plabr_2309	6.645e-65	233.0	COG0284@1|root,COG0284@2|Bacteria,2IXSF@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS1_k127_3629660_2	196367.JNFG01000208_gene84	1.155e-13	80.0	COG3533@1|root,COG4733@1|root,COG3533@2|Bacteria,COG4733@2|Bacteria,1NJBA@1224|Proteobacteria,2VNM3@28216|Betaproteobacteria,1K271@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Laminin_G_3
GDHHQS1_k127_3629660_0	585531.HMPREF0063_10664	1.392e-56	218.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DP0V@85009|Propionibacteriales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_3629660_1	56780.SYN_01127	1.827e-51	202.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3646371_0	566466.NOR53_597	1.382e-24	121.0	COG1361@1|root,COG3055@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1T4S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GDHHQS1_k127_367259_8	756272.Plabr_1541	2.908e-70	242.0	COG0673@1|root,COG0673@2|Bacteria,2IYHX@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_367259_6	237368.SCABRO_01122	1.766e-75	259.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS1_k127_367259_4	1280950.HJO_04595	1.403e-84	287.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,43WF1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS1_k127_367259_3	273068.TTE1628	4.367e-88	299.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,42F1M@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS1_k127_367259_1	1408422.JHYF01000006_gene1212	6.915e-102	339.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
GDHHQS1_k127_367259_2	1408422.JHYF01000006_gene1211	3.904e-91	308.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,36HRK@31979|Clostridiaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS1_k127_367259_7	926569.ANT_02630	2.515e-75	264.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS1_k127_367259_10	945713.IALB_0254	8.752e-21	96.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_0254|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_367259_5	644282.Deba_1749	1.209e-81	285.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
GDHHQS1_k127_367259_11	880072.Desac_0830	1.059e-19	98.0	COG0745@1|root,COG0745@2|Bacteria,1PGXZ@1224|Proteobacteria,437JJ@68525|delta/epsilon subdivisions,2X2TK@28221|Deltaproteobacteria,2MSE0@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_367259_12	666686.B1NLA3E_19605	5.92e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,1ZD1X@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ykoG3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS1_k127_367259_0	667014.Thein_1130	9.45e-139	454.0	COG2204@1|root,COG2204@2|Bacteria,2GGZ6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_367259_9	243231.GSU0599	1.369e-69	246.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,43SU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GDHHQS1_k127_3751499_1	756272.Plabr_2403	1.064e-59	211.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_3751499_0	1185876.BN8_00694	1.829e-147	478.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
GDHHQS1_k127_3751499_2	1279017.AQYJ01000026_gene259	4.837e-21	100.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	CBM_2,CBM_4_9,Cellulase,Glyco_hydro_16,PSCyt3,PSD3,PSD4,PSD5,RicinB_lectin_2,YceI
GDHHQS1_k127_3755784_0	452637.Oter_0134	4.885e-180	579.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase,DUF4038,DUF5060,Glyco_hydro_115
GDHHQS1_k127_3755784_1	344747.PM8797T_05400	6.229e-39	151.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_3811334_6	742743.HMPREF9453_01037	1.286e-27	116.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_3811334_4	745411.B3C1_02760	1.276e-43	177.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1J4IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretory pathway, component	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS1_k127_3811334_2	886293.Sinac_1401	1.729e-85	289.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS1_k127_3811334_8	243231.GSU0581	1.638e-21	95.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS1_k127_3811334_7	1142394.PSMK_24200	2.977e-26	110.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS1_k127_3811334_3	247490.KSU1_D0953	4.396e-46	186.0	COG0681@1|root,COG0681@2|Bacteria,2IYWI@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS1_k127_3811334_0	1343740.M271_09315	0.0	1047.0	COG3250@1|root,COG3250@2|Bacteria,2I3FI@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
GDHHQS1_k127_3811334_5	886293.Sinac_5785	9.971e-38	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_3811334_1	1499967.BAYZ01000182_gene4414	2.277e-256	807.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GDHHQS1_k127_3834676_1	1286171.EAL2_c14130	6.948e-102	346.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,25UT7@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
GDHHQS1_k127_3834676_2	945713.IALB_2664	4.141e-31	128.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS1_k127_3834676_0	484770.UFO1_0827	1.113e-114	379.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4H2CQ@909932|Negativicutes	909932|Negativicutes	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS1_k127_3837991_2	886293.Sinac_6057	5.743e-82	278.0	COG0525@1|root,COG0525@2|Bacteria,2IWU4@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS1_k127_3837991_0	237368.SCABRO_00256	5.762e-208	660.0	COG1158@1|root,COG1158@2|Bacteria,2IXV3@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS1_k127_3837991_4	237368.SCABRO_00255	9.58e-28	120.0	COG0237@1|root,COG0237@2|Bacteria,2J02E@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GDHHQS1_k127_3837991_1	1123373.ATXI01000023_gene1785	5.449e-123	417.0	COG0438@1|root,COG0438@2|Bacteria,2GHK9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3837991_5	886293.Sinac_3399	0.0001506	51.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS1_k127_3837991_3	314230.DSM3645_18836	7.733e-45	166.0	COG0780@1|root,COG0780@2|Bacteria,2J07W@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GDHHQS1_k127_3875197_2	247634.GPB2148_818	4.444e-22	111.0	COG3828@1|root,COG3828@2|Bacteria,1NAIA@1224|Proteobacteria,1SDA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS1_k127_3875197_0	388413.ALPR1_16703	9.027e-116	390.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS1_k127_3875197_1	1492738.FEM21_28300	5.902e-97	327.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,1IEXU@117743|Flavobacteriia,2NYKK@237|Flavobacterium	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_3887583_2	1121912.AUHD01000005_gene1574	1.39e-05	54.0	COG1595@1|root,COG1595@2|Bacteria,4NSDS@976|Bacteroidetes,1IIVX@117743|Flavobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_3887583_1	768672.Desfe_1319	2.957e-10	72.0	COG0441@1|root,arCOG00401@2157|Archaea,2XQ02@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)	thrS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
GDHHQS1_k127_3887583_0	1289387.AUKW01000011_gene749	2.863e-60	226.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS1_k127_3914869_2	545695.TREAZ_3007	1.201e-39	151.0	COG0145@1|root,COG0145@2|Bacteria,2JAMB@203691|Spirochaetes	203691|Spirochaetes	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
GDHHQS1_k127_3914869_1	237368.SCABRO_00764	2.101e-52	191.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
GDHHQS1_k127_3914869_0	401526.TcarDRAFT_0626	1.156e-94	321.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,4H2S4@909932|Negativicutes	2|Bacteria	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
GDHHQS1_k127_3914869_4	1408439.JHXW01000012_gene889	5.653e-17	90.0	COG1396@1|root,COG1974@1|root,COG1396@2|Bacteria,COG1974@2|Bacteria,3799F@32066|Fusobacteria	32066|Fusobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
GDHHQS1_k127_3914869_3	1380394.JADL01000021_gene1868	1.134e-27	122.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2JSB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS1_k127_3937281_0	1123277.KB893174_gene6067	4.063e-65	240.0	28M5E@1|root,2ZAJ7@2|Bacteria,4NZ10@976|Bacteroidetes,47TH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3937281_1	368408.Tpen_1559	4.684e-16	85.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_3938314_1	247490.KSU1_C0166	6.378e-56	211.0	COG0772@1|root,COG0772@2|Bacteria,2IZRI@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS1_k127_3938314_0	237368.SCABRO_01931	1.731e-86	305.0	COG0728@1|root,COG0728@2|Bacteria,2IYP2@203682|Planctomycetes	203682|Planctomycetes	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS1_k127_3993516_0	1123371.ATXH01000007_gene541	1.5e-91	307.0	COG0119@1|root,COG0119@2|Bacteria,2GHCY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
GDHHQS1_k127_3993516_6	314285.KT71_11870	0.0005555	44.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1S16H@1236|Gammaproteobacteria,1J8QT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS1_k127_3993516_5	113395.AXAI01000002_gene5563	4.75e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,3JTGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS1_k127_3993516_2	1392502.JNIO01000002_gene63	7.603e-54	193.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS1_k127_3993516_4	247490.KSU1_C0961	7.615e-28	117.0	COG0613@1|root,COG0781@1|root,COG0613@2|Bacteria,COG0781@2|Bacteria,2J058@203682|Planctomycetes	203682|Planctomycetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB,PHP
GDHHQS1_k127_3993516_1	1123508.JH636445_gene6831	3.564e-81	283.0	COG1192@1|root,COG1192@2|Bacteria,2IX5Z@203682|Planctomycetes	203682|Planctomycetes	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_3993516_3	234267.Acid_1173	4.36e-49	178.0	COG0657@1|root,COG0657@2|Bacteria,3Y2TC@57723|Acidobacteria	57723|Acidobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS1_k127_4031566_0	756272.Plabr_1443	4.953e-73	255.0	COG0673@1|root,COG0673@2|Bacteria,2J247@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_4031566_1	329726.AM1_5789	8.958e-14	82.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,DUF1565,Glyco_hydro_10
GDHHQS1_k127_4068603_0	179408.Osc7112_4909	9.856e-101	356.0	COG0438@1|root,COG0463@1|root,COG1215@1|root,COG1216@1|root,COG5185@1|root,COG0438@2|Bacteria,COG0463@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG5185@2|Bacteria,1G3E3@1117|Cyanobacteria,1HH4F@1150|Oscillatoriales	1117|Cyanobacteria	DM	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
GDHHQS1_k127_4072496_0	886293.Sinac_2391	7.689e-78	269.0	COG0454@1|root,COG0454@2|Bacteria,2J1E7@203682|Planctomycetes	203682|Planctomycetes	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS1_k127_4072496_2	314230.DSM3645_14090	9.831e-54	207.0	COG1413@1|root,COG3828@1|root,COG1413@2|Bacteria,COG3828@2|Bacteria,2IX8S@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_4072496_1	452637.Oter_3509	1.694e-66	240.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_4075934_2	1123508.JH636439_gene1031	1.504e-19	94.0	COG1183@1|root,COG1183@2|Bacteria,2IZHR@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_4075934_1	1123508.JH636439_gene1032	2.162e-55	202.0	COG0688@1|root,COG0688@2|Bacteria,2IXE7@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS1_k127_4075934_0	1191523.MROS_2270	1.587e-123	398.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
GDHHQS1_k127_4129992_2	639030.JHVA01000001_gene2962	2.231e-40	161.0	COG2159@1|root,COG2159@2|Bacteria,3Y7XT@57723|Acidobacteria,2JNXE@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS1_k127_4129992_3	945713.IALB_2435	8.267e-26	111.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
GDHHQS1_k127_4129992_1	945713.IALB_2434	3.363e-72	248.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS1_k127_4129992_0	945713.IALB_2433	3.067e-125	414.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
GDHHQS1_k127_4134742_1	497964.CfE428DRAFT_0715	5.715e-69	235.0	COG1082@1|root,COG1082@2|Bacteria,46TGS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_4134742_2	661478.OP10G_1032	6.997e-42	178.0	COG4354@1|root,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
GDHHQS1_k127_4134742_0	661478.OP10G_1031	5.812e-258	828.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
GDHHQS1_k127_4180652_1	370438.PTH_2719	1.337e-32	128.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS1_k127_4180652_0	945713.IALB_0896	4.253e-168	542.0	COG0606@1|root,COG0606@2|Bacteria	2|Bacteria	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS1_k127_4180652_3	167539.Pro_1558	3.115e-24	104.0	COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria,1MMR6@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
GDHHQS1_k127_4180652_4	1192759.AKIB01000061_gene1987	0.0006012	50.0	COG0847@1|root,COG0847@2|Bacteria,1PHTX@1224|Proteobacteria,2UF74@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4180652_2	65393.PCC7424_4304	4.918e-27	120.0	COG0863@1|root,COG0863@2|Bacteria,1G2AV@1117|Cyanobacteria,3KHEN@43988|Cyanothece	1117|Cyanobacteria	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
GDHHQS1_k127_4189477_1	237368.SCABRO_01468	2.697e-86	297.0	COG0769@1|root,COG0769@2|Bacteria,2IWUT@203682|Planctomycetes	203682|Planctomycetes	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_4189477_2	203119.Cthe_0977	4.065e-78	279.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_4189477_0	1142394.PSMK_24980	1.977e-101	342.0	COG0472@1|root,COG0472@2|Bacteria,2IXU1@203682|Planctomycetes	203682|Planctomycetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
GDHHQS1_k127_4190738_1	1340493.JNIF01000004_gene359	5.828e-74	269.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_4190738_2	880073.Calab_3098	6.116e-60	215.0	COG2755@1|root,COG2755@2|Bacteria,2NQ5Y@2323|unclassified Bacteria	2|Bacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	Lipase_GDSL_2
GDHHQS1_k127_4190738_3	156889.Mmc1_3097	5.923e-11	75.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
GDHHQS1_k127_4190738_0	1304880.JAGB01000001_gene36	5.106e-162	554.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS1_k127_4196465_0	1379698.RBG1_1C00001G1531	2.32e-106	366.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS1_k127_4196465_1	1321815.HMPREF9193_00690	2.028e-61	220.0	COG1696@1|root,COG1696@2|Bacteria,2J6VT@203691|Spirochaetes	203691|Spirochaetes	M	membrane protein involved in D-alanine export	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
GDHHQS1_k127_4211308_2	9365.XP_007518453.1	1.662e-06	59.0	2CDB0@1|root,2S5FA@2759|Eukaryota,38DQQ@33154|Opisthokonta,3BH0H@33208|Metazoa,3CSSQ@33213|Bilateria,485TW@7711|Chordata,48UXT@7742|Vertebrata,3J2KV@40674|Mammalia	33208|Metazoa	C	Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine)	DIO3	GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004800,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0006915,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009653,GO:0009887,GO:0009987,GO:0010721,GO:0010817,GO:0012501,GO:0016020,GO:0016491,GO:0018958,GO:0019336,GO:0019439,GO:0022008,GO:0022603,GO:0030154,GO:0030182,GO:0032501,GO:0032502,GO:0033798,GO:0040008,GO:0040014,GO:0040018,GO:0042219,GO:0042403,GO:0042404,GO:0042445,GO:0042447,GO:0042461,GO:0042462,GO:0042478,GO:0042480,GO:0042670,GO:0043010,GO:0044237,GO:0044248,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045927,GO:0046530,GO:0046532,GO:0046533,GO:0046549,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048592,GO:0048593,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051239,GO:0051240,GO:0051241,GO:0051402,GO:0051960,GO:0051961,GO:0055114,GO:0060041,GO:0060042,GO:0060219,GO:0060284,GO:0065007,GO:0065008,GO:0070997,GO:0071704,GO:0071944,GO:0090596,GO:0097474,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901616,GO:1990009,GO:2000026,GO:2000027	1.21.99.3,1.21.99.4	ko:K01562,ko:K07754	ko04919,map04919	-	-	-	ko00000,ko00001,ko01000	-	-	-	T4_deiodinase
GDHHQS1_k127_4211308_1	338963.Pcar_0774	2.147e-69	243.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
GDHHQS1_k127_4211308_0	1142394.PSMK_00010	8.334e-96	323.0	COG0593@1|root,COG0593@2|Bacteria,2IWXU@203682|Planctomycetes	203682|Planctomycetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS1_k127_4242427_1	309807.SRU_0556	5.836e-45	173.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1FJ12@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS1_k127_4242427_2	314230.DSM3645_16200	1.064e-28	132.0	COG1305@1|root,COG1305@2|Bacteria,2IYTT@203682|Planctomycetes	203682|Planctomycetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GDHHQS1_k127_4242427_0	314230.DSM3645_18751	2.66e-143	474.0	COG0608@1|root,COG0608@2|Bacteria,2IXVB@203682|Planctomycetes	203682|Planctomycetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS1_k127_4279067_1	903818.KI912268_gene1124	4.931e-50	183.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS1_k127_4279067_0	439235.Dalk_2559	9.36e-316	993.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GDHHQS1_k127_428103_1	452637.Oter_2196	4.907e-144	461.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_428103_0	1267535.KB906767_gene3674	2.371e-185	584.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_428103_2	935948.KE386494_gene874	6.002e-117	385.0	COG1082@1|root,COG1082@2|Bacteria,1V08R@1239|Firmicutes,24C9W@186801|Clostridia,42J0W@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_428103_3	177437.HRM2_15930	2.639e-05	50.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS1_k127_4324102_3	706587.Desti_3800	5.455e-56	201.0	COG1309@1|root,COG1309@2|Bacteria,1NAQF@1224|Proteobacteria,42S96@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS1_k127_4324102_0	1396418.BATQ01000110_gene4779	4.514e-104	342.0	COG1335@1|root,COG1335@2|Bacteria,46X9S@74201|Verrucomicrobia,2IV56@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS1_k127_4324102_2	1230343.CANP01000037_gene2754	1.405e-60	213.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1JF2S@118969|Legionellales	118969|Legionellales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS1_k127_4324102_4	1267535.KB906767_gene661	7.708e-31	136.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GDHHQS1_k127_4324102_1	1203550.HMPREF1475_00695	4.033e-90	313.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
GDHHQS1_k127_4339559_3	1224164.B843_02115	0.0001828	53.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,22ND2@1653|Corynebacteriaceae	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_4339559_0	398767.Glov_2754	3.102e-108	361.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
GDHHQS1_k127_4339559_1	1499685.CCFJ01000023_gene2434	2.85e-95	326.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
GDHHQS1_k127_4339559_2	714943.Mucpa_5116	8.381e-28	113.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes	976|Bacteroidetes	DZ	FG-GAP repeat protein	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
GDHHQS1_k127_4363551_2	443144.GM21_1782	1.752e-79	271.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS1_k127_4363551_3	247490.KSU1_B0672	4.193e-49	193.0	COG2385@1|root,COG2385@2|Bacteria,2J08W@203682|Planctomycetes	203682|Planctomycetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS1_k127_4363551_1	886293.Sinac_5630	2.279e-84	296.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS1_k127_4404005_0	1142394.PSMK_14530	7.579e-157	503.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS1_k127_4404005_2	1122216.AUHW01000002_gene1838	1.124e-07	62.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes	909932|Negativicutes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS1_k127_4404005_3	561175.KB894104_gene1147	0.0002773	49.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria,4EKPH@85012|Streptosporangiales	201174|Actinobacteria	M	rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
GDHHQS1_k127_4404005_1	1168067.JAGP01000001_gene1648	2.077e-30	137.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS1_k127_4407382_1	237368.SCABRO_03331	3.151e-56	216.0	COG0706@1|root,COG0706@2|Bacteria,2IYA0@203682|Planctomycetes	203682|Planctomycetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,PDZ_2,YidC_periplas
GDHHQS1_k127_4407382_0	452637.Oter_0884	1.256e-65	241.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,3K7N8@414999|Opitutae	414999|Opitutae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS1_k127_4408417_0	1041930.Mtc_2241	8.809e-123	396.0	COG0338@1|root,arCOG03416@2157|Archaea,2XWJX@28890|Euryarchaeota	28890|Euryarchaeota	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
GDHHQS1_k127_4408417_2	880070.Cycma_0099	7.005e-77	271.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
GDHHQS1_k127_444428_0	452637.Oter_2229	1.13e-250	809.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
GDHHQS1_k127_444428_1	583355.Caka_3039	4.342e-173	562.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4495067_1	1123242.JH636435_gene1403	1.184e-83	293.0	COG1207@1|root,COG1207@2|Bacteria,2IXBV@203682|Planctomycetes	203682|Planctomycetes	M	Sugar nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
GDHHQS1_k127_4495067_2	999550.KI421507_gene1688	1.803e-16	81.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS1_k127_4495067_0	1123371.ATXH01000007_gene541	1.172e-157	510.0	COG0119@1|root,COG0119@2|Bacteria,2GHCY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
GDHHQS1_k127_4495067_3	1121285.AUFK01000009_gene1148	2.179e-12	76.0	COG4733@1|root,COG4733@2|Bacteria,4PKYK@976|Bacteroidetes,1IJHK@117743|Flavobacteriia,3ZQWF@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Pec_lyase_C,fn3
GDHHQS1_k127_450513_3	795359.TOPB45_1315	1.714e-10	70.0	COG0620@1|root,COG0620@2|Bacteria,2GHBR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
GDHHQS1_k127_450513_2	1096930.L284_04265	1.429e-21	109.0	COG1807@1|root,COG1807@2|Bacteria,1R7IS@1224|Proteobacteria,2U51N@28211|Alphaproteobacteria,2KDIS@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_450513_1	1123508.JH636450_gene7124	1.078e-31	135.0	COG4191@1|root,COG4191@2|Bacteria,2IYZD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS1_k127_450513_0	1122917.KB899661_gene1195	1.593e-64	226.0	COG1262@1|root,COG4409@1|root,COG1262@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
GDHHQS1_k127_4520373_2	517418.Ctha_1865	3.092e-51	195.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CHU_C,Calx-beta,ChW,Flg_new,Glug,Phage_TTP_12,RCC1
GDHHQS1_k127_4520373_0	382464.ABSI01000005_gene1368	3.033e-83	282.0	COG0681@1|root,COG0681@2|Bacteria,46V6F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS1_k127_4520373_3	999419.HMPREF1077_03046	1.849e-50	189.0	COG2303@1|root,COG2303@2|Bacteria,4PKTW@976|Bacteroidetes,2FS8M@200643|Bacteroidia,22XM0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_4520373_1	478741.JAFS01000002_gene991	7.048e-56	202.0	COG3465@1|root,COG3465@2|Bacteria	2|Bacteria	-	-	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427,ko:K09388	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Macro,Methylase_S
GDHHQS1_k127_4524444_4	1499968.TCA2_3202	0.0009726	42.0	COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,26QHQ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	desK	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS1_k127_4524444_0	56780.SYN_01019	1.755e-56	205.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria,2MRK4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_4524444_1	56780.SYN_00975	1.298e-51	190.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SH0@68525|delta/epsilon subdivisions,2WPFU@28221|Deltaproteobacteria,2MS7I@213462|Syntrophobacterales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW34H-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS1_k127_4524444_2	1159870.KB907784_gene3009	2.179e-27	129.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
GDHHQS1_k127_4524444_3	1265505.ATUG01000002_gene2235	2.927e-20	98.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2MIVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-6	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
GDHHQS1_k127_4528616_2	886293.Sinac_4186	6.138e-13	81.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
GDHHQS1_k127_4528616_1	641524.ADICYQ_0727	1.417e-181	610.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4528616_0	1123008.KB905697_gene3293	3.704e-225	738.0	COG1233@1|root,COG1233@2|Bacteria,4PKWE@976|Bacteroidetes,2FNQX@200643|Bacteroidia,231HP@171551|Porphyromonadaceae	976|Bacteroidetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS1_k127_4538368_2	1142394.PSMK_25540	1.357e-41	160.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
GDHHQS1_k127_4538368_3	550540.Fbal_1304	0.0003623	51.0	COG1335@1|root,COG1335@2|Bacteria,1QU95@1224|Proteobacteria,1SF7X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
GDHHQS1_k127_4538368_0	760192.Halhy_3656	4.171e-198	628.0	COG4946@1|root,COG4946@2|Bacteria,4NJFC@976|Bacteroidetes,1IW2A@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4538368_1	234267.Acid_7524	7.191e-121	404.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria	57723|Acidobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_4584905_0	1121335.Clst_0927	2.176e-129	420.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
GDHHQS1_k127_4584905_1	314230.DSM3645_13810	6.056e-56	221.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
GDHHQS1_k127_463152_2	1499967.BAYZ01000069_gene1917	5.909e-23	100.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_463152_0	1303518.CCALI_02745	4.724e-68	257.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HD_5,HWE_HK,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS1_k127_463152_1	234267.Acid_5440	4.718e-39	154.0	COG4784@1|root,COG4784@2|Bacteria	2|Bacteria	S	Peptidase m48 ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS1_k127_4656337_2	1123248.KB893329_gene4463	3.206e-72	248.0	COG1082@1|root,COG1082@2|Bacteria,4PJ9G@976|Bacteroidetes,1IZP5@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_4656337_0	530564.Psta_2822	1.112e-121	404.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_4656337_1	641524.ADICYQ_4401	1.384e-106	360.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_4656337_3	886293.Sinac_5626	4.644e-20	96.0	COG3291@1|root,COG3291@2|Bacteria,2J552@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_4673865_2	1121413.JMKT01000015_gene286	8.705e-09	63.0	COG0457@1|root,COG0457@2|Bacteria,1MW49@1224|Proteobacteria,42N7T@68525|delta/epsilon subdivisions,2WK4Z@28221|Deltaproteobacteria,2M9R1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4673865_0	1121335.Clst_1584	4.063e-57	216.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia,3WI4U@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
GDHHQS1_k127_4673865_1	575540.Isop_0002	4.645e-27	115.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS1_k127_4695835_0	1123242.JH636434_gene3779	4.713e-244	766.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS1_k127_4695835_2	1121456.ATVA01000002_gene3204	3.06e-44	176.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria,2M9V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS1_k127_4695835_1	1304888.ATWF01000001_gene2370	3.733e-236	760.0	COG0841@1|root,COG0841@2|Bacteria,2GESU@200930|Deferribacteres	200930|Deferribacteres	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS1_k127_4745306_2	1147.D082_15870	1.967e-47	175.0	COG0018@1|root,COG0018@2|Bacteria,1G15V@1117|Cyanobacteria,1H53V@1142|Synechocystis	1117|Cyanobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS1_k127_4745306_0	1001585.MDS_1229	4.643e-111	368.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1YJRS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	transporter MgtE	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS1_k127_4745306_3	868864.Dester_1272	4.115e-44	164.0	COG0432@1|root,COG0432@2|Bacteria,2G41G@200783|Aquificae	200783|Aquificae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS1_k127_4745306_1	1142394.PSMK_29570	5e-57	207.0	COG0325@1|root,COG0325@2|Bacteria,2IZ9R@203682|Planctomycetes	203682|Planctomycetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS1_k127_4745306_4	1142394.PSMK_18360	6.482e-41	168.0	COG2208@1|root,COG2208@2|Bacteria,2J0ZD@203682|Planctomycetes	203682|Planctomycetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS1_k127_4745306_5	627192.SLG_13900	2.988e-15	78.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K8K6@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
GDHHQS1_k127_4808405_2	502025.Hoch_2275	5.461e-37	145.0	arCOG10116@1|root,315E2@2|Bacteria,1MYJ7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4808405_1	1408473.JHXO01000006_gene1102	3.817e-124	413.0	COG3579@1|root,COG3579@2|Bacteria,4NJ3J@976|Bacteroidetes,2FMZY@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
GDHHQS1_k127_4808405_0	368408.Tpen_1559	9.356e-143	469.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4879470_4	635013.TherJR_1545	2.274e-14	78.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia,262TE@186807|Peptococcaceae	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
GDHHQS1_k127_4879470_3	1210884.HG799466_gene12588	5.012e-24	106.0	COG1558@1|root,COG1558@2|Bacteria,2J09G@203682|Planctomycetes	203682|Planctomycetes	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_4879470_6	203122.Sde_2189	0.0009424	46.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,468DU@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
GDHHQS1_k127_4879470_1	1125863.JAFN01000001_gene697	2.943e-63	237.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2WJS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
GDHHQS1_k127_4879470_2	309803.CTN_0465	6.962e-30	131.0	COG1536@1|root,COG1536@2|Bacteria,2GCFH@200918|Thermotogae	200918|Thermotogae	N	flagellar motor switch protein FliG	fliG	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046982,GO:0046983	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
GDHHQS1_k127_4879470_5	1379270.AUXF01000002_gene1662	5.631e-06	55.0	COG1317@1|root,COG1317@2|Bacteria,1ZTXY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
GDHHQS1_k127_4879470_0	1347392.CCEZ01000043_gene316	2.333e-87	296.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,36FF4@31979|Clostridiaceae	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS1_k127_4929573_0	234267.Acid_6145	2.368e-134	439.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_4929573_1	877411.JMMA01000002_gene232	2.696e-38	158.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS1_k127_4929573_2	335543.Sfum_0412	3.569e-05	48.0	COG1575@1|root,COG1575@2|Bacteria,1PWVZ@1224|Proteobacteria,4349B@68525|delta/epsilon subdivisions,2X2PW@28221|Deltaproteobacteria,2MRJX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS1_k127_4940220_0	1142394.PSMK_19560	1.594e-87	304.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_4940220_1	1410674.JNKU01000002_gene2380	1.441e-22	106.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli	91061|Bacilli	J	30S ribosomal protein S12 methylthiotransferase	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS1_k127_494091_1	1123274.KB899424_gene2967	5.908e-147	477.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2J5WW@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS1_k127_494091_0	344747.PM8797T_23786	1.746e-161	515.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS1_k127_4966826_0	547042.BACCOPRO_00992	1.029e-94	331.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
GDHHQS1_k127_4966826_2	471853.Bcav_3932	2.207e-05	51.0	COG3152@1|root,COG3152@2|Bacteria,2GSS4@201174|Actinobacteria	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_4966826_1	468556.AQYG01000050_gene3238	2.796e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4GBZI@85026|Gordoniaceae	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS1_k127_5023840_2	1123278.KB893436_gene603	8.328e-22	100.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_5023840_1	933262.AXAM01000059_gene2911	9.057e-53	197.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1R609@1224|Proteobacteria,42MTJ@68525|delta/epsilon subdivisions,2WJYM@28221|Deltaproteobacteria,2MMSJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Pkinase
GDHHQS1_k127_5023840_0	1142394.PSMK_26660	2.474e-214	684.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,2IXPK@203682|Planctomycetes	203682|Planctomycetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS1_k127_503675_5	794903.OPIT5_11195	7.912e-16	82.0	COG2165@1|root,COG2165@2|Bacteria,46YF8@74201|Verrucomicrobia,3K9G0@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS1_k127_503675_3	247490.KSU1_C1680	4.231e-36	145.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS1_k127_503675_2	1499967.BAYZ01000080_gene896	1.272e-47	175.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_1,Flavodoxin_5
GDHHQS1_k127_503675_1	1499967.BAYZ01000075_gene2071	2.232e-70	258.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS-HPr
GDHHQS1_k127_503675_4	530564.Psta_0119	3.35e-28	122.0	COG0546@1|root,COG0546@2|Bacteria,2J0RU@203682|Planctomycetes	203682|Planctomycetes	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS1_k127_503675_0	583355.Caka_0413	1.266e-74	261.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS1_k127_5059990_1	344747.PM8797T_32255	1.365e-120	393.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS1_k127_5059990_0	497964.CfE428DRAFT_0774	1.825e-145	467.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
GDHHQS1_k127_5059990_2	886293.Sinac_0404	5.19e-111	374.0	COG1721@1|root,COG1721@2|Bacteria,2IY8R@203682|Planctomycetes	203682|Planctomycetes	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS1_k127_5082102_4	518766.Rmar_1560	4.624e-65	225.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1FJ4D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS1_k127_5082102_1	1142394.PSMK_01740	6.041e-135	437.0	COG0468@1|root,COG0468@2|Bacteria,2IX4U@203682|Planctomycetes	203682|Planctomycetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS1_k127_5082102_6	70601.3256485	6.684e-29	123.0	COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,242VR@183968|Thermococci	183968|Thermococci	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS1_k127_5082102_3	886293.Sinac_5975	1.628e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS1_k127_5082102_2	867903.ThesuDRAFT_00439	1.469e-104	359.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS1_k127_5082102_0	234267.Acid_3246	1.442e-152	497.0	COG0673@1|root,COG0673@2|Bacteria,3Y76D@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_5082102_5	868595.Desca_2343	4.845e-60	223.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS1_k127_5108167_2	1396141.BATP01000027_gene1160	4.522e-20	106.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_5108167_3	485917.Phep_2792	1.807e-10	75.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes	976|Bacteroidetes	G	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5108167_1	717606.PaecuDRAFT_2334	1.447e-41	177.0	COG1404@1|root,COG2133@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78,3.4.21.62,3.4.21.66	ko:K01206,ko:K01218,ko:K01342,ko:K08651,ko:K14645	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Glyco_hydro_26,PA14,PKD,PPC,Peptidase_S8
GDHHQS1_k127_5108167_0	517417.Cpar_1280	2.138e-113	371.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
GDHHQS1_k127_5137542_2	1254432.SCE1572_50535	1.682e-15	77.0	COG1879@1|root,COG1879@2|Bacteria,1MU95@1224|Proteobacteria	1224|Proteobacteria	G	Periplasmic binding protein LacI transcriptional regulator	alsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS1_k127_5137542_0	1396141.BATP01000025_gene970	2.653e-185	595.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	2|Bacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GDHHQS1_k127_5137542_1	452637.Oter_3322	1.736e-99	335.0	COG1172@1|root,COG1172@2|Bacteria,46V2W@74201|Verrucomicrobia,3K95F@414999|Opitutae	414999|Opitutae	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS1_k127_515744_1	314230.DSM3645_09437	0.0	1159.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS1_k127_515744_0	886293.Sinac_0499	0.0	1332.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GDHHQS1_k127_5182383_0	944480.ATUV01000002_gene40	1.188e-148	479.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,2M6MV@213113|Desulfurellales	28221|Deltaproteobacteria	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
GDHHQS1_k127_5182383_2	1142394.PSMK_25420	8.575e-10	71.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_5182383_1	1121904.ARBP01000019_gene2760	6.31e-63	219.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_522161_0	530564.Psta_1965	4.509e-22	102.0	COG2165@1|root,COG2165@2|Bacteria,2J10X@203682|Planctomycetes	203682|Planctomycetes	U	Pfam:N_methyl_2	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GDHHQS1_k127_522161_1	406552.NJ7G_2327	2.257e-07	61.0	arCOG10710@1|root,arCOG10710@2157|Archaea,2XXDN@28890|Euryarchaeota,23VNN@183963|Halobacteria	183963|Halobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
GDHHQS1_k127_5224664_0	583355.Caka_1736	3.557e-141	469.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
GDHHQS1_k127_5224664_1	1185876.BN8_06488	2.621e-91	309.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_5315737_2	1168034.FH5T_03605	4.705e-08	55.0	28KP8@1|root,2ZA7D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5315737_0	1396418.BATQ01000109_gene4730	1.277e-100	343.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_5315737_1	452637.Oter_3237	6.569e-75	266.0	COG3507@1|root,COG3507@2|Bacteria,46TKI@74201|Verrucomicrobia,3KA3C@414999|Opitutae	2|Bacteria	G	PFAM glycoside hydrolase family 62	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Glyco_hydro_43
GDHHQS1_k127_5347933_2	237368.SCABRO_00402	1.547e-17	87.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS1_k127_5347933_0	880070.Cycma_0165	5.242e-153	493.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_5347933_1	314230.DSM3645_04730	2.04e-113	380.0	COG0673@1|root,COG0673@2|Bacteria,2IYHX@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_5349684_1	1307759.JOMJ01000003_gene1655	5.23e-74	284.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,43D2U@68525|delta/epsilon subdivisions,2X8A0@28221|Deltaproteobacteria,2MHEC@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
GDHHQS1_k127_5349684_2	903818.KI912268_gene2810	3.121e-69	268.0	COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	Big_2,CARDB,Cadherin-like,Peptidase_M30,SLH,fn3
GDHHQS1_k127_5349684_0	1307759.JOMJ01000003_gene1654	1.899e-80	290.0	COG3121@1|root,COG3121@2|Bacteria,1NSS2@1224|Proteobacteria	1224|Proteobacteria	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5381723_2	1330700.JQNC01000003_gene911	7.215e-25	110.0	COG3258@1|root,COG3258@2|Bacteria,1WMNM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS1_k127_5381723_1	760192.Halhy_4736	7.491e-42	175.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,4NEUZ@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
GDHHQS1_k127_5381723_0	760192.Halhy_1278	2.913e-49	198.0	COG1262@1|root,COG4886@1|root,COG5635@1|root,COG1262@2|Bacteria,COG4886@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS,NACHT,Trypsin_2
GDHHQS1_k127_5381723_4	1489678.RDMS_13850	0.0001528	53.0	COG3271@1|root,COG3271@2|Bacteria,1WJIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase C39, bacteriocin processing	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
GDHHQS1_k127_5381723_3	383381.EH30_06760	8.37e-10	64.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria,2K15P@204457|Sphingomonadales	204457|Sphingomonadales	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS1_k127_5556150_1	478741.JAFS01000002_gene991	2.299e-46	168.0	COG3465@1|root,COG3465@2|Bacteria	2|Bacteria	-	-	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427,ko:K09388	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Macro,Methylase_S
GDHHQS1_k127_5556150_3	904296.HMPREF9124_1836	1.32e-40	157.0	2DNAB@1|root,32WEV@2|Bacteria,1VED3@1239|Firmicutes,24QBP@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
GDHHQS1_k127_5556150_0	113395.AXAI01000015_gene511	4.422e-230	742.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,3JSSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS1_k127_5556150_4	671143.DAMO_1357	5.051e-36	151.0	COG1466@1|root,COG1466@2|Bacteria,2NPN5@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta,DNA_pol3_gamma3
GDHHQS1_k127_5556150_5	1206731.BAGB01000026_gene3089	9.704e-21	104.0	COG1621@1|root,COG1621@2|Bacteria,2I9BS@201174|Actinobacteria,4FVDR@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N,Glyco_hydro_43
GDHHQS1_k127_5556150_2	555079.Toce_0565	2.145e-42	163.0	COG1533@1|root,COG1533@2|Bacteria,1TQA6@1239|Firmicutes,24A2T@186801|Clostridia,42F9K@68295|Thermoanaerobacterales	186801|Clostridia	L	Domain of unknown function (DUF1848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
GDHHQS1_k127_5584759_1	483219.LILAB_10590	2.462e-08	64.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,zf-HC2
GDHHQS1_k127_5584759_0	1329516.JPST01000024_gene2143	2.13e-159	509.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,4HCRT@91061|Bacilli	91061|Bacilli	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
GDHHQS1_k127_561436_6	237368.SCABRO_03437	0.0001392	50.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_03437|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_561436_0	864565.HMPREF0379_1073	4.281e-110	365.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,24818@186801|Clostridia	186801|Clostridia	M	GDP-mannose 4,6 dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_561436_4	1303518.CCALI_02127	8.666e-70	248.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS1_k127_561436_2	1121033.AUCF01000009_gene1150	3.346e-104	352.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2U6E3@28211|Alphaproteobacteria,2JVSX@204441|Rhodospirillales	204441|Rhodospirillales	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
GDHHQS1_k127_561436_1	1244869.H261_02826	4.312e-108	357.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS1_k127_561436_3	1244869.H261_02821	3.269e-102	346.0	COG3958@1|root,COG3958@2|Bacteria,1MWIX@1224|Proteobacteria,2U2QX@28211|Alphaproteobacteria,2JYPW@204441|Rhodospirillales	204441|Rhodospirillales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS1_k127_561436_5	536233.CLO_2972	4.855e-36	141.0	COG4122@1|root,COG4122@2|Bacteria,1VKRG@1239|Firmicutes	1239|Firmicutes	M	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
GDHHQS1_k127_5619596_4	1121459.AQXE01000008_gene835	2.055e-28	121.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2M8JR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
GDHHQS1_k127_5619596_2	865861.AZSU01000001_gene54	3.504e-51	184.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,36HZ3@31979|Clostridiaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS1_k127_5619596_3	247490.KSU1_C1678	1.721e-37	146.0	COG0103@1|root,COG0103@2|Bacteria,2J01J@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS1_k127_5619596_0	314230.DSM3645_04900	1.083e-102	348.0	COG0002@1|root,COG0002@2|Bacteria,2IXTC@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS1_k127_5619596_5	886293.Sinac_6475	1.757e-05	54.0	COG3295@1|root,COG3295@2|Bacteria,2IZY0@203682|Planctomycetes	203682|Planctomycetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5619596_1	177437.HRM2_11540	5.496e-101	336.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2MJ22@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
GDHHQS1_k127_5621885_0	1122216.AUHW01000009_gene1676	1.601e-150	481.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4H24Z@909932|Negativicutes	909932|Negativicutes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS1_k127_5621885_1	1304880.JAGB01000001_gene427	6.581e-147	497.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,24C9J@186801|Clostridia	186801|Clostridia	C	PFAM NADH flavin oxidoreductase NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
GDHHQS1_k127_5621885_2	1410626.JHXB01000005_gene1414	8.574e-78	291.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,27ICB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS1_k127_5621885_3	35754.JNYJ01000037_gene4651	3.626e-35	138.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DH2X@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS1_k127_5635464_5	575540.Isop_0883	7.986e-32	135.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
GDHHQS1_k127_5635464_2	575540.Isop_0883	6.078e-46	178.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
GDHHQS1_k127_5635464_3	169963.lmo1900	1.966e-35	138.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,26KJG@186820|Listeriaceae	91061|Bacilli	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
GDHHQS1_k127_5635464_0	720554.Clocl_2125	3.351e-93	314.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3WHX6@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS1_k127_5635464_4	394503.Ccel_1332	1.633e-33	144.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,36ECT@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
GDHHQS1_k127_5635464_1	489825.LYNGBM3L_08940	9.668e-84	281.0	COG0436@1|root,COG0436@2|Bacteria,1G0NC@1117|Cyanobacteria,1H74E@1150|Oscillatoriales	1117|Cyanobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_5644975_3	671143.DAMO_0314	1.141e-09	70.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS1_k127_5644975_0	521674.Plim_1742	5.325e-166	532.0	COG0422@1|root,COG0422@2|Bacteria,2IWV7@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
GDHHQS1_k127_5644975_1	1123242.JH636434_gene3574	9.288e-127	415.0	COG2133@1|root,COG2133@2|Bacteria,2IXUJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
GDHHQS1_k127_5649010_0	1173027.Mic7113_4331	2.707e-165	526.0	COG0436@1|root,COG0436@2|Bacteria,1G24E@1117|Cyanobacteria,1H6X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS1_k127_5649010_2	55601.VANGNB10_cII0499c	1.062e-06	55.0	2EEQQ@1|root,338IE@2|Bacteria,1N816@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5649010_1	1121405.dsmv_1706	5.451e-102	341.0	COG0697@1|root,COG0697@2|Bacteria,1NS7A@1224|Proteobacteria,42MCJ@68525|delta/epsilon subdivisions,2WKQ4@28221|Deltaproteobacteria,2MIE6@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS1_k127_5662907_0	518766.Rmar_2319	4.571e-15	80.0	COG1319@1|root,COG1319@2|Bacteria,4PMRI@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5662907_1	344747.PM8797T_07909	1.193e-08	65.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_5716563_3	643562.Daes_1470	3.405e-57	203.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2M90H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS1_k127_5716563_1	1089553.Tph_c22610	1.156e-80	280.0	COG0731@1|root,COG0731@2|Bacteria,1TSYW@1239|Firmicutes,24CEP@186801|Clostridia,42ID6@68295|Thermoanaerobacterales	186801|Clostridia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS1_k127_5716563_6	521674.Plim_2345	0.0005953	46.0	2E3N9@1|root,33M91@2|Bacteria,2J1E4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5716563_0	1142394.PSMK_28200	1.982e-93	317.0	COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS1_k127_5716563_4	497964.CfE428DRAFT_5014	1.518e-29	138.0	COG2304@1|root,COG3055@1|root,COG3119@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3055@2|Bacteria,COG3119@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	rapB1	-	3.2.1.4	ko:K01179,ko:K07004,ko:K12548	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Laminin_G_3
GDHHQS1_k127_5716563_5	880070.Cycma_0727	2.292e-12	81.0	COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia	976|Bacteroidetes	S	Kelch repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_4,Kelch_6,Malectin,PKD
GDHHQS1_k127_5716563_2	621372.ACIH01000184_gene3163	3.464e-69	239.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,26SJE@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
GDHHQS1_k127_5723664_2	1380390.JIAT01000011_gene2883	1.49e-14	83.0	COG0028@1|root,COG0515@1|root,COG1409@1|root,COG1749@1|root,COG2374@1|root,COG3291@1|root,COG3509@1|root,COG4733@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1409@2|Bacteria,COG1749@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,COG4733@2|Bacteria,2I2X3@201174|Actinobacteria,4CSIX@84995|Rubrobacteria	84995|Rubrobacteria	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,fn3
GDHHQS1_k127_5723664_1	767817.Desgi_1325	3.889e-80	281.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS1_k127_5723664_0	247490.KSU1_D0952	3.653e-181	583.0	COG0481@1|root,COG0481@2|Bacteria,2IXI5@203682|Planctomycetes	203682|Planctomycetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS1_k127_5746617_0	595460.RRSWK_07152	2.348e-141	456.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,NPCBM_assoc,Sulfatase
GDHHQS1_k127_5746617_2	518766.Rmar_1623	2.674e-79	273.0	COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_5746617_3	886293.Sinac_0022	7.435e-62	224.0	COG0667@1|root,COG0667@2|Bacteria,2J2CM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_5746617_1	927658.AJUM01000007_gene2722	4.322e-120	404.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
GDHHQS1_k127_5767132_3	497964.CfE428DRAFT_0827	2.573e-27	112.0	COG2223@1|root,COG2223@2|Bacteria,46UH2@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS1_k127_5767132_0	765952.PUV_14580	4.86e-315	975.0	COG0365@1|root,COG0365@2|Bacteria,2JFRM@204428|Chlamydiae	204428|Chlamydiae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS1_k127_5767132_1	290317.Cpha266_0557	3.116e-91	315.0	COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi	1090|Chlorobi	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_5767132_2	1307761.L21SP2_1854	5.324e-60	209.0	COG0190@1|root,COG0190@2|Bacteria,2J5PR@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS1_k127_5802140_4	1232437.KL662020_gene703	1.848e-40	151.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2MICK@213118|Desulfobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_5802140_2	1167006.UWK_02169	9.938e-75	272.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_5802140_1	1403819.BATR01000070_gene2105	2.121e-77	269.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_5802140_0	240016.ABIZ01000001_gene5157	5.312e-116	387.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS1_k127_5802140_5	1121447.JONL01000001_gene610	5.674e-40	160.0	COG3884@1|root,COG3884@2|Bacteria,1NBT0@1224|Proteobacteria,42W3W@68525|delta/epsilon subdivisions,2WR9F@28221|Deltaproteobacteria,2MCDM@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
GDHHQS1_k127_5802140_3	1169144.KB910992_gene2872	7.345e-64	229.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS1_k127_5806001_0	927677.ALVU02000001_gene2257	1.023e-248	784.0	COG0286@1|root,COG0286@2|Bacteria,1G119@1117|Cyanobacteria	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
GDHHQS1_k127_5806001_3	1301098.PKB_2431	3.383e-56	213.0	COG2188@1|root,COG3746@1|root,COG2188@2|Bacteria,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,1T5CM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
GDHHQS1_k127_5806001_1	153721.MYP_2017	2.432e-125	409.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
GDHHQS1_k127_5806001_2	153721.MYP_2018	2.761e-109	362.0	COG0573@1|root,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,47KM7@768503|Cytophagia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS1_k127_5806001_4	1192034.CAP_3327	1.455e-18	98.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
GDHHQS1_k127_5867357_0	1123508.JH636441_gene3331	2.892e-116	385.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS1_k127_5867357_4	314260.PB2503_09384	2.03e-39	151.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS1_k127_5867357_6	247490.KSU1_C1199	1.462e-19	95.0	COG0244@1|root,COG0244@2|Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GDHHQS1_k127_5867357_1	247490.KSU1_C1198	1.104e-72	251.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS1_k127_5867357_2	344747.PM8797T_12131	1.302e-53	191.0	COG0080@1|root,COG0080@2|Bacteria,2IZ97@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS1_k127_5867357_3	1142394.PSMK_08340	1.824e-51	188.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
GDHHQS1_k127_5867357_7	1142394.PSMK_08330	9.449e-14	76.0	COG0690@1|root,COG0690@2|Bacteria,2J0E7@203682|Planctomycetes	203682|Planctomycetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
GDHHQS1_k127_5867357_9	1408445.JHXP01000047_gene1751	4.886e-06	48.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1JECV@118969|Legionellales	118969|Legionellales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
GDHHQS1_k127_5867357_8	886293.Sinac_0509	1.691e-08	59.0	COG0267@1|root,COG0267@2|Bacteria,2J1HX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GDHHQS1_k127_5867357_5	575540.Isop_0113	1.001e-26	109.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS1_k127_5867771_0	1142394.PSMK_20220	5.233e-220	696.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS1_k127_5867771_1	1142394.PSMK_20230	1.397e-122	407.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS1_k127_5898603_2	290397.Adeh_0991	9.218e-11	76.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS1_k127_5898603_3	1242864.D187_006851	1.602e-10	75.0	COG4733@1|root,COG4733@2|Bacteria,1R6EB@1224|Proteobacteria,430XN@68525|delta/epsilon subdivisions,2WW14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Starch binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_20,CBM_25,fn3
GDHHQS1_k127_5898603_0	203119.Cthe_0732	2.394e-77	277.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS1_k127_5898603_1	588581.Cpap_0808	7.514e-67	235.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS1_k127_5904968_1	1120985.AUMI01000017_gene2668	4.175e-14	73.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H2K2@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
GDHHQS1_k127_5904968_0	886293.Sinac_5147	1.17e-37	149.0	COG0013@1|root,COG0013@2|Bacteria,2IX30@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS1_k127_5905010_1	706587.Desti_4248	4.786e-173	547.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_5905010_0	756272.Plabr_1302	2.129e-184	584.0	COG0156@1|root,COG0156@2|Bacteria,2IX0H@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_5905010_2	313596.RB2501_11342	6.831e-124	402.0	COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,1I7AI@117743|Flavobacteriia	976|Bacteroidetes	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
GDHHQS1_k127_5905010_4	1410624.JNKK01000013_gene1497	9.523e-18	91.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,27J3E@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	maa	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
GDHHQS1_k127_5905010_6	575540.Isop_3395	1.954e-10	71.0	COG2165@1|root,COG2165@2|Bacteria,2J1VN@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_5905010_5	661478.OP10G_0260	1.022e-14	83.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_5905010_3	1121904.ARBP01000025_gene6085	2.665e-40	160.0	COG2273@1|root,COG2730@1|root,COG3291@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	chiA	-	3.2.1.4,3.2.1.73,3.2.1.80	ko:K01179,ko:K01216,ko:K03332,ko:K20276	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R00879,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM_6,CHU_C,F5_F8_type_C,Glyco_hydro_16,PKD
GDHHQS1_k127_6002423_1	1031711.RSPO_c03174	2.893e-74	264.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria,1KBJW@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
GDHHQS1_k127_6002423_2	192952.MM_1144	1.114e-12	82.0	COG5563@1|root,arCOG03499@1|root,arCOG03499@2157|Archaea,arCOG03501@2157|Archaea	2157|Archaea	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
GDHHQS1_k127_6002423_3	1499967.BAYZ01000068_gene1935	2.315e-11	78.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
GDHHQS1_k127_6002423_4	1120963.KB894492_gene1472	3.202e-09	60.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria,2Q4A5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	A	RNA 3'-terminal phosphate cyclase (RTC), insert domain	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
GDHHQS1_k127_6002423_0	5722.XP_001321901.1	3.112e-77	272.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
GDHHQS1_k127_6008515_3	1111134.HMPREF1253_1121	1.622e-27	123.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,22GFD@1570339|Peptoniphilaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS1_k127_6008515_2	1396141.BATP01000027_gene1160	1.413e-35	158.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_6008515_4	485917.Phep_2792	9.585e-12	79.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes	976|Bacteroidetes	G	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6008515_1	102125.Xen7305DRAFT_00048450	4.679e-36	160.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1G2CB@1117|Cyanobacteria,3VM5E@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,Lectin_C
GDHHQS1_k127_6008515_0	56780.SYN_02504	2.503e-149	484.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM MltA domain protein	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
GDHHQS1_k127_605104_4	96561.Dole_3140	1.048e-42	160.0	2EE83@1|root,3382N@2|Bacteria,1N5WA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_605104_5	443143.GM18_3029	8.15e-27	118.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,42XEQ@68525|delta/epsilon subdivisions,2WTD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
GDHHQS1_k127_605104_1	604354.TSIB_0325	1.249e-115	387.0	arCOG08626@1|root,arCOG08626@2157|Archaea,2Y4FM@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_605104_0	1142394.PSMK_10170	1.851e-228	722.0	COG0449@1|root,COG0449@2|Bacteria,2IXF9@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS1_k127_605104_3	944481.JAFP01000001_gene263	2.383e-51	188.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,2M71A@213113|Desulfurellales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS1_k127_605104_2	1280664.AUIX01000003_gene216	4.069e-52	196.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,4BWR2@830|Butyrivibrio	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS1_k127_6096558_2	243090.RB1732	5.017e-45	169.0	COG0388@1|root,COG0388@2|Bacteria,2J3H5@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS1_k127_6096558_1	1220534.B655_1298	1.733e-51	187.0	arCOG13108@1|root,arCOG13108@2157|Archaea,2Y5X6@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6096558_0	497964.CfE428DRAFT_1820	3.146e-286	892.0	COG1506@1|root,COG1506@2|Bacteria,46UJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS1_k127_6131263_1	504472.Slin_3461	4.226e-58	204.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_6131263_2	247490.KSU1_D0285	2.317e-39	155.0	2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
GDHHQS1_k127_6131263_0	314230.DSM3645_16305	1.571e-59	220.0	COG0472@1|root,COG0472@2|Bacteria,2IXB8@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS1_k127_6134509_0	247490.KSU1_C1126	7.539e-271	871.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS1_k127_6134509_1	1123277.KB893197_gene6125	1.653e-135	441.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47K5E@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS1_k127_6134509_3	143224.JQMD01000002_gene181	7.869e-66	231.0	COG0823@1|root,COG0823@2|Bacteria,4NM2C@976|Bacteroidetes,1I7Q6@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_615729_0	497964.CfE428DRAFT_2264	5.137e-160	512.0	COG3119@1|root,COG3119@2|Bacteria,46UNC@74201|Verrucomicrobia	2|Bacteria	P	Domain of unknown function (DUF4976)	mdsA	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_615729_1	525904.Tter_1998	4.117e-08	65.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,Collagen_bind_2,DUF4038,DUF5060
GDHHQS1_k127_617513_3	1232410.KI421428_gene1029	6.879e-18	91.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,42XQR@68525|delta/epsilon subdivisions,2X2FN@28221|Deltaproteobacteria,43V6S@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
GDHHQS1_k127_617513_0	1265505.ATUG01000003_gene722	8.004e-88	297.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria,2MIAJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
GDHHQS1_k127_617513_2	56780.SYN_00388	2.548e-57	205.0	COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,42N61@68525|delta/epsilon subdivisions,2WM0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
GDHHQS1_k127_617513_5	13035.Dacsa_2398	0.000127	51.0	COG2165@1|root,COG2165@2|Bacteria,1G7YC@1117|Cyanobacteria	1117|Cyanobacteria	NU	PFAM Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_GH
GDHHQS1_k127_617513_1	42256.RradSPS_2920	1.068e-71	247.0	COG0590@1|root,COG0590@2|Bacteria,2I9KR@201174|Actinobacteria	201174|Actinobacteria	FJ	CMP dCMP deaminase, zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GDHHQS1_k127_617513_4	452637.Oter_1398	7.448e-13	77.0	arCOG07336@1|root,2Z8ST@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6245036_1	1303518.CCALI_02288	1.192e-37	151.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_6245036_0	1142394.PSMK_30020	1.586e-85	300.0	COG1192@1|root,COG3170@1|root,COG1192@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496,ko:K09000	-	-	-	-	ko00000,ko02048,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_6260949_0	688269.Theth_0252	9.283e-131	424.0	COG0031@1|root,COG0031@2|Bacteria,2GC4Y@200918|Thermotogae	200918|Thermotogae	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS1_k127_6260949_1	1410618.JNKI01000027_gene307	3.499e-73	261.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4H2P5@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS1_k127_6260949_3	879212.DespoDRAFT_01329	1.123e-20	94.0	COG1937@1|root,COG1937@2|Bacteria,1N9P2@1224|Proteobacteria,42UPN@68525|delta/epsilon subdivisions,2WQYG@28221|Deltaproteobacteria,2MM9G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS1_k127_6260949_2	1307759.JOMJ01000003_gene2354	1.733e-64	237.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_6266188_1	268407.PWYN_20620	1.942e-38	159.0	COG2755@1|root,COG3250@1|root,COG3291@1|root,COG3307@1|root,COG3867@1|root,COG2755@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG3307@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	3.2.1.23,3.2.1.8	ko:K01181,ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,Wzy_C
GDHHQS1_k127_6266188_0	344747.PM8797T_06060	1.313e-136	446.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_6298850_0	368407.Memar_1301	3.218e-70	244.0	COG1465@1|root,arCOG04353@2157|Archaea,2XSXD@28890|Euryarchaeota,2N9AV@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
GDHHQS1_k127_6298850_1	555779.Dthio_PD3207	1.886e-28	115.0	COG1598@1|root,COG1598@2|Bacteria,1NCC0@1224|Proteobacteria,42UMY@68525|delta/epsilon subdivisions,2WQUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS1_k127_6314716_2	714943.Mucpa_1134	2.344e-52	188.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes,1IVY2@117747|Sphingobacteriia	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
GDHHQS1_k127_6314716_0	1121904.ARBP01000041_gene4944	1.975e-122	412.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,47Q1K@768503|Cytophagia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
GDHHQS1_k127_6314716_1	1166018.FAES_3721	3.16e-102	342.0	COG1073@1|root,COG1073@2|Bacteria,4NIV6@976|Bacteroidetes,47QEA@768503|Cytophagia	976|Bacteroidetes	S	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,DLH
GDHHQS1_k127_6344607_0	926550.CLDAP_22570	1.341e-111	373.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
GDHHQS1_k127_6368431_2	1191523.MROS_2687	6.895e-39	147.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS1_k127_6368431_0	1123278.KB893499_gene386	6.801e-126	413.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
GDHHQS1_k127_6368431_1	497964.CfE428DRAFT_4864	1.022e-63	227.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6368431_3	794903.OPIT5_27930	1.665e-18	89.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3KA2Y@414999|Opitutae	414999|Opitutae	KLT	Protein of unknown function (DUF4019)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
GDHHQS1_k127_6391368_4	518766.Rmar_2641	4.49e-15	80.0	COG3682@1|root,COG3682@2|Bacteria,4P9FT@976|Bacteroidetes,1FJNX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS1_k127_6391368_5	330214.NIDE4013	4.409e-07	57.0	2EQ22@1|root,33HNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6391368_3	1142394.PSMK_24200	2.072e-26	111.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS1_k127_6391368_0	909663.KI867150_gene2237	1.505e-196	624.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MQ6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
GDHHQS1_k127_6391368_1	1047013.AQSP01000134_gene1338	3.126e-130	432.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS1_k127_6391368_2	926569.ANT_09520	4.945e-37	141.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_6396323_1	709991.Odosp_3390	1.018e-92	313.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes,2G2XU@200643|Bacteroidia,231K5@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS1_k127_6396323_2	457570.Nther_0417	1.394e-22	100.0	2E32K@1|root,32Y2U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6396323_0	56780.SYN_01220	1.171e-135	446.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2MR4K@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS1_k127_6404772_0	485913.Krac_3872	5.482e-190	610.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
GDHHQS1_k127_6404772_1	1210884.HG799469_gene14187	7.735e-133	432.0	COG0381@1|root,COG0381@2|Bacteria,2IWR6@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS1_k127_6404772_2	1125863.JAFN01000001_gene1531	0.0001089	49.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	A	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
GDHHQS1_k127_6437308_2	1123276.KB893245_gene1752	9.419e-20	89.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
GDHHQS1_k127_6437308_1	1150474.JQJI01000008_gene1360	3.353e-101	340.0	COG1899@1|root,COG1899@2|Bacteria,2GDSY@200918|Thermotogae	200918|Thermotogae	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6437308_0	761193.Runsl_0035	2.86e-130	425.0	COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,PfkB
GDHHQS1_k127_643958_4	1123405.AUMM01000011_gene1335	1.582e-09	59.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,26PQ1@186821|Sporolactobacillaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS1_k127_643958_0	671143.DAMO_3115	1.841e-103	353.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
GDHHQS1_k127_643958_1	886293.Sinac_6467	2.904e-97	330.0	COG4956@1|root,COG4956@2|Bacteria,2IXF3@203682|Planctomycetes	203682|Planctomycetes	S	Integral membrane protein (PIN domain superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4,TRAM
GDHHQS1_k127_643958_3	309798.COPRO5265_1577	2.483e-40	158.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AhpC-TSA
GDHHQS1_k127_643958_2	1304880.JAGB01000001_gene227	4.724e-46	170.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
GDHHQS1_k127_6452443_1	56110.Oscil6304_2695	3.605e-40	158.0	COG4625@1|root,COG4625@2|Bacteria,1GKAF@1117|Cyanobacteria,1HGZ2@1150|Oscillatoriales	1117|Cyanobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6452443_2	530564.Psta_0054	0.0007132	48.0	COG1366@1|root,COG1366@2|Bacteria,2J02R@203682|Planctomycetes	203682|Planctomycetes	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS1_k127_6452443_0	240016.ABIZ01000001_gene5155	4.17e-61	224.0	COG0845@1|root,COG0845@2|Bacteria,46WF0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
GDHHQS1_k127_6487128_3	1121098.HMPREF1534_00526	2.131e-66	250.0	COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,2FNPI@200643|Bacteroidia,4ANXT@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
GDHHQS1_k127_6487128_2	452637.Oter_2976	1.748e-88	301.0	COG3622@1|root,COG3622@2|Bacteria,46TIJ@74201|Verrucomicrobia,3K80T@414999|Opitutae	414999|Opitutae	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS1_k127_6487128_1	1304880.JAGB01000002_gene1607	2.152e-114	384.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,24MBN@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_6487128_0	1122927.KB895423_gene3757	1.604e-168	552.0	COG3420@1|root,COG4099@1|root,COG5492@1|root,COG3420@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae	91061|Bacilli	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2
GDHHQS1_k127_6562873_0	338966.Ppro_3385	1.186e-49	188.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,43TVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein CapD	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
GDHHQS1_k127_6562873_1	247490.KSU1_B0240	5.78e-32	141.0	2CFWI@1|root,32S2N@2|Bacteria,2J08K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6562873_2	757424.Hsero_0352	2.656e-08	59.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,47519@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
GDHHQS1_k127_6567790_2	1142394.PSMK_15560	9.523e-37	148.0	COG1277@1|root,COG1277@2|Bacteria,2IYX5@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GDHHQS1_k127_6567790_1	1142394.PSMK_15610	5.898e-66	250.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_6567790_3	158190.SpiGrapes_2806	2.65e-36	149.0	COG0330@1|root,COG0330@2|Bacteria,2J5TU@203691|Spirochaetes	2|Bacteria	O	HflC and HflK could regulate a protease	hflC2	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS1_k127_6567790_4	1123517.JOMR01000001_gene820	2.978e-19	101.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
GDHHQS1_k127_6567790_0	313628.LNTAR_12671	2.096e-140	464.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
GDHHQS1_k127_6584494_0	1191523.MROS_1835	2.776e-233	730.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS1_k127_6584494_2	118173.KB235910_gene5084	2.914e-19	90.0	COG0389@1|root,COG0389@2|Bacteria,1G07F@1117|Cyanobacteria,1H6YS@1150|Oscillatoriales	1117|Cyanobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
GDHHQS1_k127_6584494_1	1047013.AQSP01000084_gene768	4.58e-66	235.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS1_k127_65865_0	5722.XP_001304541.1	1.459e-38	153.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001304541.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_65865_2	1232410.KI421424_gene1807	1.165e-29	123.0	2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_65865_1	118163.Ple7327_1368	2.324e-34	146.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria,1GHAI@1117|Cyanobacteria,3VMJ1@52604|Pleurocapsales	1117|Cyanobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS1_k127_65865_3	575540.Isop_2648	9.485e-07	55.0	COG2866@1|root,COG3087@1|root,COG2866@2|Bacteria,COG3087@2|Bacteria,2J3D2@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M14 carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS1_k127_6589275_0	314230.DSM3645_24260	1.084e-43	175.0	COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes	203682|Planctomycetes	NU	pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_6589275_1	795359.TOPB45_1210	3.397e-06	56.0	COG3167@1|root,COG3167@2|Bacteria,2GGSX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GDHHQS1_k127_6589914_5	588581.Cpap_2538	2.118e-17	87.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,3WM7S@541000|Ruminococcaceae	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_6589914_2	237368.SCABRO_02734	1.237e-83	287.0	COG4786@1|root,COG4786@2|Bacteria,2IXW0@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_6589914_6	1380380.JIAX01000013_gene3076	2.32e-06	59.0	COG1261@1|root,COG1261@2|Bacteria,1MZIR@1224|Proteobacteria	1224|Proteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
GDHHQS1_k127_6589914_3	1121439.dsat_2329	1.056e-21	102.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WMYI@28221|Deltaproteobacteria,2MB2X@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
GDHHQS1_k127_6589914_1	1123371.ATXH01000024_gene1011	4.608e-85	295.0	COG1706@1|root,COG1706@2|Bacteria,2GGRG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
GDHHQS1_k127_6589914_7	1123242.JH636434_gene5076	0.0002876	48.0	COG3951@1|root,COG3951@2|Bacteria,2J4M5@203682|Planctomycetes	203682|Planctomycetes	MNO	Rod binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
GDHHQS1_k127_6589914_0	1123508.JH636444_gene5169	1.769e-92	328.0	COG1256@1|root,COG1256@2|Bacteria,2IXRV@203682|Planctomycetes	203682|Planctomycetes	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_6589914_4	237368.SCABRO_02727	9.023e-21	103.0	COG1344@1|root,COG1344@2|Bacteria,2J11W@203682|Planctomycetes	203682|Planctomycetes	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_N
GDHHQS1_k127_6597105_3	1121356.AQUW01000004_gene131	1.806e-13	81.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,22KNR@1653|Corynebacteriaceae	201174|Actinobacteria	O	Membrane protease subunits, stomatin prohibitin homologs	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS1_k127_6597105_2	1195236.CTER_0486	1.495e-26	126.0	COG2133@1|root,COG2182@1|root,COG3507@1|root,COG3669@1|root,COG3979@1|root,COG2133@2|Bacteria,COG2182@2|Bacteria,COG3507@2|Bacteria,COG3669@2|Bacteria,COG3979@2|Bacteria,1VRJN@1239|Firmicutes,24DFN@186801|Clostridia,3WIA2@541000|Ruminococcaceae	186801|Clostridia	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,RsgI_N
GDHHQS1_k127_6597105_4	376686.Fjoh_2456	3.324e-13	83.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6597105_0	237368.SCABRO_01759	4.974e-211	672.0	COG1217@1|root,COG1217@2|Bacteria,2IY3Q@203682|Planctomycetes	203682|Planctomycetes	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS1_k127_6597105_1	530564.Psta_2427	2.924e-76	265.0	COG2755@1|root,COG2755@2|Bacteria,2IZ2H@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS1_k127_663720_0	880073.Calab_1912	5.689e-68	240.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS1_k127_663720_2	1232437.KL661988_gene239	0.0001373	54.0	29XUZ@1|root,30JM7@2|Bacteria,1NNH1@1224|Proteobacteria,42X4U@68525|delta/epsilon subdivisions,2WTEM@28221|Deltaproteobacteria,2MPNB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_663720_1	706587.Desti_0293	7.328e-37	144.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS1_k127_6658409_0	1499967.BAYZ01000076_gene816	7.38e-101	335.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_6658409_3	933262.AXAM01000027_gene2098	3.335e-18	91.0	COG1633@1|root,COG1633@2|Bacteria,1RGYD@1224|Proteobacteria,42T5E@68525|delta/epsilon subdivisions,2WPKD@28221|Deltaproteobacteria,2MKDK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS1_k127_6658409_1	1167006.UWK_02169	4.088e-79	287.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_6658409_2	521674.Plim_3483	4.597e-41	169.0	COG0845@1|root,COG0845@2|Bacteria,2IXP7@203682|Planctomycetes	203682|Planctomycetes	M	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,HlyD_3,HlyD_D23
GDHHQS1_k127_6659621_4	722419.PH505_bd00190	1.78e-06	60.0	28M95@1|root,2ZAN4@2|Bacteria,1R588@1224|Proteobacteria,1RQZF@1236|Gammaproteobacteria,2PZQH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
GDHHQS1_k127_6659621_2	1303518.CCALI_02244	1.22e-10	72.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_6659621_0	1201288.M900_2069	7.249e-123	403.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2MT70@213481|Bdellovibrionales,2WJ8Y@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	PFAM DAHP synthetase I KDSA	aroG-2	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
GDHHQS1_k127_6659621_3	756499.Desde_1539	7.3e-09	67.0	COG0663@1|root,COG0663@2|Bacteria,1V72E@1239|Firmicutes,24YU6@186801|Clostridia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS1_k127_6659621_5	580340.Tlie_1588	5.869e-05	48.0	28XQZ@1|root,2ZJMK@2|Bacteria,3TCGY@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6659621_1	1279017.AQYJ01000026_gene259	7.777e-38	150.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K03932	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	CBM_2,CBM_4_9,Cellulase,Glyco_hydro_16,PSCyt3,PSD3,PSD4,PSD5,RicinB_lectin_2,YceI
GDHHQS1_k127_6666979_0	237368.SCABRO_00568	1.169e-133	446.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS1_k127_6666979_1	472759.Nhal_2666	5.922e-46	177.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1WZG8@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS1_k127_6666979_2	477974.Daud_1316	1.639e-32	133.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,260WJ@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS1_k127_66922_0	1304888.ATWF01000001_gene1910	1.415e-65	232.0	2DMBB@1|root,32GIQ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465,PKD_3,VPEP
GDHHQS1_k127_66922_1	28042.GU90_01465	1.356e-60	220.0	COG0388@1|root,COG0388@2|Bacteria,2I9ZC@201174|Actinobacteria,4E6QQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS1_k127_6748739_1	938293.CAJU020000007_gene2089	7.773e-40	153.0	2E2AR@1|root,32XG5@2|Bacteria,1VC42@1239|Firmicutes,25DRJ@186801|Clostridia	186801|Clostridia	S	AP2 domain	-	-	-	-	-	-	-	-	-	-	-	-	AP2,HNH_3
GDHHQS1_k127_6748739_0	243090.RB9026	7.081e-149	484.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_6748739_2	1303518.CCALI_01222	1.303e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_6770924_2	1122918.KB907280_gene254	3.119e-09	66.0	COG3934@1|root,COG3934@2|Bacteria,1VUFZ@1239|Firmicutes	1239|Firmicutes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5060
GDHHQS1_k127_6770924_0	517418.Ctha_1865	2.18e-42	176.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CHU_C,Calx-beta,ChW,Flg_new,Glug,Phage_TTP_12,RCC1
GDHHQS1_k127_6770924_1	794903.OPIT5_07570	1.521e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_6779200_1	247490.KSU1_C0508	5.897e-105	361.0	COG1361@1|root,COG1361@2|Bacteria,2IY9X@203682|Planctomycetes	203682|Planctomycetes	M	60 kDa outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GDHHQS1_k127_6779200_4	886293.Sinac_6217	2.179e-07	58.0	COG2204@1|root,COG2204@2|Bacteria,2J0PB@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS1_k127_6779200_3	1123508.JH636443_gene4517	5.791e-36	139.0	COG0234@1|root,COG0234@2|Bacteria,2J027@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS1_k127_6779200_0	1142394.PSMK_31900	3.727e-227	716.0	COG0459@1|root,COG0459@2|Bacteria,2IXA7@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS1_k127_6779200_2	1268635.Loa_00571	2.248e-54	194.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1JCKC@118969|Legionellales	118969|Legionellales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS1_k127_6820878_2	1121403.AUCV01000026_gene2365	4.64e-54	194.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
GDHHQS1_k127_6820878_0	589865.DaAHT2_1112	6.256e-213	678.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
GDHHQS1_k127_6820878_1	909663.KI867150_gene2007	1.303e-88	305.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS1_k127_6852599_3	265072.Mfla_2096	7.433e-06	56.0	2EKNW@1|root,33ECK@2|Bacteria,1NGE2@1224|Proteobacteria,2W51U@28216|Betaproteobacteria,2KNWC@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
GDHHQS1_k127_6852599_2	1121403.AUCV01000073_gene1307	9.093e-13	81.0	COG1345@1|root,COG3209@1|root,COG3485@1|root,COG4676@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3485@2|Bacteria,COG4676@2|Bacteria,1R0C4@1224|Proteobacteria,43CUG@68525|delta/epsilon subdivisions,2X825@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6852599_1	335543.Sfum_2359	1.016e-45	183.0	COG1345@1|root,COG1345@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6852599_0	1519464.HY22_12335	3.711e-60	221.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS1_k127_6866207_5	96561.Dole_1401	4.852e-87	295.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MIZT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS1_k127_6866207_6	555088.DealDRAFT_0043	3.083e-80	274.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
GDHHQS1_k127_6866207_9	580340.Tlie_1776	1.345e-48	177.0	COG0394@1|root,COG0394@2|Bacteria,3TB6Z@508458|Synergistetes	508458|Synergistetes	T	PFAM Protein-tyrosine phosphatase, low molecular weight	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS1_k127_6866207_2	886293.Sinac_6591	1.294e-122	408.0	COG3385@1|root,COG3385@2|Bacteria,2IZ65@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GDHHQS1_k127_6866207_3	1047013.AQSP01000123_gene1540	3.347e-117	388.0	COG0177@1|root,COG0177@2|Bacteria,2NQYE@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF2400)	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF2400,EndIII_4Fe-2S,HhH-GPD
GDHHQS1_k127_6866207_12	448385.sce2204	2.558e-20	96.0	COG1871@1|root,COG1871@2|Bacteria,1RI55@1224|Proteobacteria,42W4V@68525|delta/epsilon subdivisions,2WRZ4@28221|Deltaproteobacteria,2Z39D@29|Myxococcales	28221|Deltaproteobacteria	NT	CheD chemotactic sensory transduction	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
GDHHQS1_k127_6866207_4	1121324.CLIT_5c00520	1.503e-115	378.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia	186801|Clostridia	P	transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GDHHQS1_k127_6866207_1	1499967.BAYZ01000095_gene4213	3.337e-180	578.0	COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
GDHHQS1_k127_6866207_7	56780.SYN_02123	1.368e-73	254.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1N731@1224|Proteobacteria,42VC4@68525|delta/epsilon subdivisions,2WRDM@28221|Deltaproteobacteria,2MQMC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
GDHHQS1_k127_6866207_11	688269.Theth_0309	1.078e-26	115.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS1_k127_6866207_10	688269.Theth_0309	2.287e-41	157.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS1_k127_6866207_8	706587.Desti_1245	3.673e-65	225.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MRP3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
GDHHQS1_k127_6871171_1	1047013.AQSP01000125_gene2640	1.607e-130	423.0	COG2211@1|root,COG2211@2|Bacteria,2NPEZ@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
GDHHQS1_k127_6871171_0	383372.Rcas_0372	0.0	1202.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi,37711@32061|Chloroflexia	32061|Chloroflexia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS1_k127_6871171_2	1121468.AUBR01000005_gene101	8.135e-77	261.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42EQ1@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS1_k127_6897853_1	861299.J421_4334	4.234e-34	136.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS1_k127_6897853_0	1121939.L861_10215	1.212e-36	143.0	COG4813@1|root,COG4813@2|Bacteria,1P43S@1224|Proteobacteria,1SKF4@1236|Gammaproteobacteria,1XNCC@135619|Oceanospirillales	135619|Oceanospirillales	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS1_k127_6908479_1	1142394.PSMK_11840	1.053e-68	255.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS1_k127_6908479_0	118173.KB235914_gene4272	6e-94	328.0	COG1524@1|root,COG2931@1|root,COG1524@2|Bacteria,COG2931@2|Bacteria,1G6I0@1117|Cyanobacteria,1HB7N@1150|Oscillatoriales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
GDHHQS1_k127_6908479_2	886293.Sinac_5728	4.331e-57	219.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS1_k127_6917280_0	1329516.JPST01000036_gene3018	1.083e-53	204.0	2AUEM@1|root,31K2N@2|Bacteria,1UPSN@1239|Firmicutes,4IVA4@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF5309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5309
GDHHQS1_k127_6926892_3	323259.Mhun_2715	1.068e-27	113.0	arCOG03086@1|root,arCOG03086@2157|Archaea	2157|Archaea	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS1_k127_6926892_5	679926.Mpet_1534	1.575e-19	89.0	COG1598@1|root,arCOG02412@2157|Archaea,2Y1KY@28890|Euryarchaeota,2NB5X@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6926892_0	497964.CfE428DRAFT_0790	5.677e-144	467.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
GDHHQS1_k127_6926892_1	521460.Athe_1156	1.255e-54	201.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,42F9Z@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS1_k127_6926892_2	886293.Sinac_5692	3.499e-50	189.0	COG2220@1|root,COG2220@2|Bacteria,2J2KB@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6926892_4	218851.Aquca_037_00077.1	1.064e-22	104.0	COG1063@1|root,KOG0024@2759|Eukaryota,37QX2@33090|Viridiplantae,3GAKK@35493|Streptophyta	35493|Streptophyta	Q	Sorbitol dehydrogenase-like	-	GO:0003674,GO:0003824,GO:0003939,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0008150,GO:0008152,GO:0009506,GO:0016491,GO:0016614,GO:0016616,GO:0030054,GO:0044424,GO:0044444,GO:0044464,GO:0055044,GO:0055114	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_6941486_1	237368.SCABRO_01725	1.049e-36	142.0	COG3635@1|root,COG3635@2|Bacteria,2IXCZ@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
GDHHQS1_k127_6941486_0	247490.KSU1_C1278	2.972e-140	456.0	COG0527@1|root,COG0527@2|Bacteria,2IY8N@203682|Planctomycetes	203682|Planctomycetes	E	aspartate kinase, monofunctional class	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
GDHHQS1_k127_6941486_2	1121127.JAFA01000018_gene161	3.875e-26	109.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VTZ8@28216|Betaproteobacteria,1K9NF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
GDHHQS1_k127_6948449_1	237368.SCABRO_01711	1.712e-39	161.0	COG1533@1|root,COG1533@2|Bacteria,2J47J@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase activity	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS1_k127_6948449_0	460265.Mnod_7349	2.86e-41	159.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS1_k127_6948449_3	1117318.PRUB_22556	0.0006183	48.0	28UR3@1|root,2ZGVE@2|Bacteria,1RB70@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6950155_5	1121285.AUFK01000009_gene1148	3.245e-12	79.0	COG4733@1|root,COG4733@2|Bacteria,4PKYK@976|Bacteroidetes,1IJHK@117743|Flavobacteriia,3ZQWF@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Pec_lyase_C,fn3
GDHHQS1_k127_6950155_1	28072.Nos7524_1554	4.75e-24	116.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,1G2VV@1117|Cyanobacteria,1HQES@1161|Nostocales	1117|Cyanobacteria	Q	Laminin G domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS1_k127_6950155_2	1111479.AXAR01000028_gene1484	4.299e-23	109.0	COG4122@1|root,COG4122@2|Bacteria,1VK28@1239|Firmicutes,4HPCV@91061|Bacilli,278WW@186823|Alicyclobacillaceae	91061|Bacilli	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
GDHHQS1_k127_6950155_4	631362.Thi970DRAFT_04850	5.406e-13	72.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,1STWE@1236|Gammaproteobacteria,1X1NR@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_6950155_0	686340.Metal_2587	9.486e-27	111.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,1XGQR@135618|Methylococcales	135618|Methylococcales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
GDHHQS1_k127_6950155_6	1122970.AUHC01000001_gene882	5.354e-06	55.0	2DNRM@1|root,32YT2@2|Bacteria,1N8BS@1224|Proteobacteria,2UKRD@28211|Alphaproteobacteria,2K61Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS1_k127_6950155_3	402777.KB235903_gene1096	2.805e-15	82.0	COG1487@1|root,COG1487@2|Bacteria,1G5BH@1117|Cyanobacteria,1HBRP@1150|Oscillatoriales	1117|Cyanobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS1_k127_6978646_1	1121904.ARBP01000022_gene3521	9.264e-28	126.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS1_k127_6978646_0	344747.PM8797T_24121	4.334e-140	460.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS1_k127_6980095_2	426117.M446_1718	1.686e-08	64.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,1JS69@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S1C family	htrA2	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS1_k127_6980095_0	1168034.FH5T_19355	3.479e-153	499.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_6980095_1	383372.Rcas_3813	6.176e-77	273.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	stsA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
GDHHQS1_k127_6981599_2	237368.SCABRO_00124	4.732e-47	170.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5,ABC_transp_aux
GDHHQS1_k127_6981599_0	237368.SCABRO_00123	2.763e-284	887.0	COG3225@1|root,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
GDHHQS1_k127_7024673_0	1122609.AUGT01000008_gene2868	6.578e-26	125.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
GDHHQS1_k127_7172127_1	886293.Sinac_7553	8.29e-13	82.0	COG3712@1|root,COG3712@2|Bacteria,2J2V7@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS1_k127_7172127_0	1396141.BATP01000027_gene1160	3.116e-36	159.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_718753_0	234267.Acid_5704	4.647e-211	668.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
GDHHQS1_k127_718753_1	1121428.DESHY_150098___1	7.748e-151	488.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GDHHQS1_k127_718753_4	1121382.JQKG01000023_gene1514	4.582e-57	204.0	COG0066@1|root,COG0066@2|Bacteria,1WIV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GDHHQS1_k127_718753_2	521674.Plim_2376	4.967e-117	394.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS1_k127_718753_3	1047013.AQSP01000114_gene714	1.14e-63	222.0	COG4912@1|root,COG4912@2|Bacteria,2NRX9@2323|unclassified Bacteria	2|Bacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS1_k127_7221203_1	604331.AUHY01000028_gene1746	1.137e-59	216.0	COG0593@1|root,COG0593@2|Bacteria,1WIHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS1_k127_7221203_0	247490.KSU1_C0960	2.203e-101	340.0	COG0552@1|root,COG0552@2|Bacteria,2IXAG@203682|Planctomycetes	203682|Planctomycetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS1_k127_7221203_2	583355.Caka_0996	4.62e-52	191.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Glyco_hydro_85,PA14
GDHHQS1_k127_7231544_4	1242864.D187_006851	4.709e-07	63.0	COG4733@1|root,COG4733@2|Bacteria,1R6EB@1224|Proteobacteria,430XN@68525|delta/epsilon subdivisions,2WW14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Starch binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_20,CBM_25,fn3
GDHHQS1_k127_7231544_3	192952.MM_2804	1.69e-14	88.0	arCOG03499@1|root,arCOG03499@2157|Archaea	2157|Archaea	G	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
GDHHQS1_k127_7231544_5	1094980.Mpsy_3087	1.422e-06	62.0	COG4870@1|root,arCOG02516@1|root,arCOG02542@1|root,arCOG02552@1|root,arCOG02516@2157|Archaea,arCOG02542@2157|Archaea,arCOG02552@2157|Archaea,arCOG03607@2157|Archaea,2XWQ1@28890|Euryarchaeota,2NAG9@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD,Peptidase_C1
GDHHQS1_k127_7231544_1	247490.KSU1_D0284	4.554e-52	188.0	COG0105@1|root,COG0105@2|Bacteria,2IZQ6@203682|Planctomycetes	203682|Planctomycetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS1_k127_7231544_2	521674.Plim_4077	7.554e-27	119.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
GDHHQS1_k127_7231544_0	264732.Moth_1329	3.134e-69	244.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,42FFX@68295|Thermoanaerobacterales	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
GDHHQS1_k127_72381_3	761193.Runsl_0424	6.051e-09	59.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,47K76@768503|Cytophagia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
GDHHQS1_k127_72381_0	1123276.KB893246_gene732	1.652e-133	437.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,47N3Z@768503|Cytophagia	976|Bacteroidetes	S	Acetyl xylan esterase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS1_k127_72381_1	237368.SCABRO_00204	4.986e-50	186.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS1_k127_72381_2	1254432.SCE1572_26605	3.498e-15	79.0	COG0327@1|root,COG0327@2|Bacteria,1R34P@1224|Proteobacteria,42MAY@68525|delta/epsilon subdivisions,2X5HJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
GDHHQS1_k127_7260786_0	56780.SYN_00515	3.646e-73	252.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MR44@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS1_k127_7260786_1	237368.SCABRO_02563	3.257e-56	202.0	COG2078@1|root,COG2078@2|Bacteria,2J349@203682|Planctomycetes	203682|Planctomycetes	S	AMMECR1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
GDHHQS1_k127_7260786_2	1142394.PSMK_15110	4.187e-05	55.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS1_k127_7260786_3	866774.HMPREF9248_0764	4.733e-05	48.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4CVHU@84998|Coriobacteriia	84998|Coriobacteriia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS1_k127_7276054_1	1408422.JHYF01000004_gene1695	9.335e-98	335.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
GDHHQS1_k127_7276054_0	76114.c1A84	2.386e-106	351.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS1_k127_7318129_1	1123065.ATWL01000016_gene1977	7.665e-39	148.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GDHHQS1_k127_7318129_2	1303518.CCALI_01450	8.732e-15	84.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_7318129_0	1123508.JH636439_gene943	1.296e-90	310.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Calx-beta,DUF1863,PQQ,PQQ_2,PQQ_3,P_proprotein,Peptidase_S8,SBBP,VCBS
GDHHQS1_k127_7335114_1	997884.HMPREF1068_03560	2.325e-52	193.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,2FN7H@200643|Bacteroidia,4AMIY@815|Bacteroidaceae	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS1_k127_7335114_0	517418.Ctha_1789	3.478e-143	461.0	COG1088@1|root,COG1088@2|Bacteria,1FDIF@1090|Chlorobi	1090|Chlorobi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS1_k127_7335114_3	429009.Adeg_0321	5.084e-43	172.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,42FGD@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_7335114_4	159087.Daro_1253	9.326e-38	154.0	COG2230@1|root,COG2230@2|Bacteria,1QWG5@1224|Proteobacteria,2W08Z@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS1_k127_7335114_2	118168.MC7420_2219	1.428e-50	188.0	COG4627@1|root,COG4627@2|Bacteria,1G57B@1117|Cyanobacteria,1HAWR@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS1_k127_7335114_5	237368.SCABRO_03065	1.973e-32	134.0	COG0438@1|root,COG0438@2|Bacteria,2IYPI@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
GDHHQS1_k127_7408731_2	1142394.PSMK_24590	2.561e-19	95.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GDHHQS1_k127_7408731_1	333138.LQ50_21730	1.207e-115	387.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS1_k127_7408731_0	616991.JPOO01000001_gene2850	2.334e-177	568.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_7408731_3	754436.JCM19237_3629	0.0001056	54.0	COG3420@1|root,COG3420@2|Bacteria,1R629@1224|Proteobacteria	1224|Proteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7414588_2	1303518.CCALI_01450	5.698e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_7414588_1	192952.MM_2804	1.016e-13	85.0	arCOG03499@1|root,arCOG03499@2157|Archaea	2157|Archaea	G	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
GDHHQS1_k127_7414588_0	96561.Dole_1704	3.181e-47	195.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7423342_1	744872.Spica_1647	1.048e-52	187.0	COG0347@1|root,COG0347@2|Bacteria,2J7M4@203691|Spirochaetes	203691|Spirochaetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
GDHHQS1_k127_7423342_0	671143.DAMO_1697	3.893e-193	611.0	COG0004@1|root,COG0004@2|Bacteria,2NP8F@2323|unclassified Bacteria	2|Bacteria	P	Ammonium Transporter Family	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS1_k127_7428541_0	439235.Dalk_3750	1.822e-141	456.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria,2MHN9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	C-terminal region of band_7	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
GDHHQS1_k127_7428541_4	439235.Dalk_3751	2.472e-32	133.0	COG1585@1|root,COG1585@2|Bacteria,1PJH9@1224|Proteobacteria,42WNG@68525|delta/epsilon subdivisions,2WRM8@28221|Deltaproteobacteria,2MKU2@213118|Desulfobacterales	28221|Deltaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
GDHHQS1_k127_7428541_2	1036674.A28LD_1047	6.546e-40	150.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,2QGXP@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
GDHHQS1_k127_7428541_1	880073.Calab_0082	2.055e-42	163.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_7428541_6	1121946.AUAX01000015_gene6048	3.554e-18	98.0	COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,2II7D@201174|Actinobacteria,4D8ZD@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,CBM_35,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3
GDHHQS1_k127_7428541_5	1396141.BATP01000027_gene1160	1.573e-31	139.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_7436564_4	706587.Desti_1022	5.328e-14	73.0	COG1456@1|root,COG1456@2|Bacteria,1R6BH@1224|Proteobacteria,42NKF@68525|delta/epsilon subdivisions,2WJ72@28221|Deltaproteobacteria,2MQZ6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
GDHHQS1_k127_7436564_3	663278.Ethha_0976	2.128e-33	134.0	COG4231@1|root,COG4231@2|Bacteria,1VAJQ@1239|Firmicutes,24MVB@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
GDHHQS1_k127_7436564_1	583355.Caka_0966	1.589e-37	153.0	COG3971@1|root,COG3971@2|Bacteria	2|Bacteria	Q	2-oxopent-4-enoate hydratase activity	mhpD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0008150,GO:0008152,GO:0008684,GO:0009056,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914	4.1.1.77,4.2.1.132,4.2.1.80	ko:K01617,ko:K02509,ko:K02554,ko:K18364	ko00350,ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00350,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R02602,R04132,R04781,R05374,R05864,R06897	RC00750,RC00751,RC01213,RC01615,RC02595,RC02672,RC02676	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_4571,iECO111_1330.ECO111_0386,iECO26_1355.ECO26_0386,iECW_1372.ECW_m0428,iEKO11_1354.EKO11_3492,iEcE24377_1341.EcE24377A_0374,iEcHS_1320.EcHS_A0414,iWFL_1372.ECW_m0428,iYL1228.KPN_04784	FAA_hydrolase
GDHHQS1_k127_7436564_0	1232410.KI421418_gene2190	5.073e-124	404.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2WK7T@28221|Deltaproteobacteria,43SX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS1_k127_7436564_2	1122917.KB899659_gene4846	1.114e-35	142.0	COG1874@1|root,COG1874@2|Bacteria,1TT9J@1239|Firmicutes,4HFG2@91061|Bacilli,26THG@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
GDHHQS1_k127_7437148_0	378806.STAUR_6445	2.722e-34	146.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS1_k127_7437148_2	1313304.CALK_1098	1.378e-07	59.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_7437148_1	317025.Tcr_0252	6.02e-09	57.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,45ZS7@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM general secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
GDHHQS1_k127_7477794_3	1410620.SHLA_36c000140	8.95e-59	209.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_7477794_0	1121904.ARBP01000013_gene349	3.073e-163	524.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS1_k127_7477794_5	247490.KSU1_C1266	6.355e-31	132.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS1_k127_7477794_2	1121468.AUBR01000016_gene2306	1.757e-93	333.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia,42FB5@68295|Thermoanaerobacterales	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS1_k127_7477794_1	246194.CHY_1804	2.915e-104	365.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,42FVQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
GDHHQS1_k127_7477794_4	247490.KSU1_D0370	1.056e-37	156.0	COG3320@1|root,COG3320@2|Bacteria,2IXFT@203682|Planctomycetes	203682|Planctomycetes	Q	dehydrogenase domain of multifunctional non-ribosomal peptide	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
GDHHQS1_k127_7480335_1	316067.Geob_3393	1.522e-49	179.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS1_k127_7480335_0	667014.Thein_0253	6.951e-163	525.0	COG0473@1|root,COG0473@2|Bacteria,2GGUW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS1_k127_7480335_2	370438.PTH_0469	3.549e-06	49.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
GDHHQS1_k127_7489462_3	240016.ABIZ01000001_gene5450	2.278e-56	207.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_7489462_0	344747.PM8797T_05840	1.671e-210	673.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_7489462_1	756272.Plabr_1963	1.333e-118	395.0	COG0612@1|root,COG0612@2|Bacteria,2IWSI@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_7489462_2	1210884.HG799468_gene13728	9.937e-99	336.0	COG0612@1|root,COG0612@2|Bacteria,2IY7Q@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS1_k127_7500972_0	439235.Dalk_1202	2.04e-87	292.0	COG0346@1|root,COG0346@2|Bacteria,1PM7Y@1224|Proteobacteria,42RD3@68525|delta/epsilon subdivisions,2WNY7@28221|Deltaproteobacteria,2MJSI@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS1_k127_7500972_2	1128421.JAGA01000001_gene2407	2.075e-21	105.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS1_k127_7500972_3	644282.Deba_2154	4.262e-16	83.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,42SJ2@68525|delta/epsilon subdivisions,2WPC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	regulator	-	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS1_k127_7500972_1	261292.Nit79A3_2197	1.526e-61	233.0	COG5002@1|root,COG5002@2|Bacteria,1PUWJ@1224|Proteobacteria,2WAYZ@28216|Betaproteobacteria,371RM@32003|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS1_k127_7549990_1	768706.Desor_0568	1.845e-72	259.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS1_k127_7549990_3	574087.Acear_1639	2.082e-11	70.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia,3WAY6@53433|Halanaerobiales	186801|Clostridia	N	PFAM flagellar hook capping protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
GDHHQS1_k127_7549990_0	1123242.JH636436_gene706	5.386e-73	267.0	COG1749@1|root,COG1749@2|Bacteria,2IYJT@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_7549990_2	1123288.SOV_3c04010	2.215e-21	101.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4H3AU@909932|Negativicutes	909932|Negativicutes	N	flagellar basal-body rod protein	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS1_k127_757898_0	697281.Mahau_2866	2.828e-93	314.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,42GHF@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM cation transporter	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
GDHHQS1_k127_757898_5	697281.Mahau_2865	1.104e-36	147.0	2EDRU@1|root,337MD@2|Bacteria,1VIEE@1239|Firmicutes,24P45@186801|Clostridia,42IRG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_757898_1	886293.Sinac_4872	4.1e-88	302.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS1_k127_757898_2	886293.Sinac_1631	1.182e-71	265.0	COG3064@1|root,COG3064@2|Bacteria,2IYZ5@203682|Planctomycetes	203682|Planctomycetes	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
GDHHQS1_k127_757898_4	1267534.KB906755_gene4346	8.646e-53	211.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria,2JIR4@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_757898_3	635013.TherJR_1504	2.263e-58	209.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,26044@186807|Peptococcaceae	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
GDHHQS1_k127_7582984_3	1379698.RBG1_1C00001G1364	1.159e-15	86.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
GDHHQS1_k127_7582984_2	756272.Plabr_2327	5.246e-31	128.0	2E296@1|root,32XEW@2|Bacteria,2J070@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7582984_0	452637.Oter_0108	5.198e-90	310.0	COG2382@1|root,COG2382@2|Bacteria,46UMK@74201|Verrucomicrobia,3K8H2@414999|Opitutae	2|Bacteria	P	Belongs to the glycosyl hydrolase 13 family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Barstar,CBM_48,Esterase
GDHHQS1_k127_7582984_1	351160.LRC67	1.803e-85	296.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,2N9BW@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS1_k127_7609876_2	756272.Plabr_0514	7.289e-134	438.0	COG0766@1|root,COG0766@2|Bacteria,2IWRI@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS1_k127_7609876_3	1089552.KI911559_gene2455	1.265e-10	72.0	COG1266@1|root,COG1266@2|Bacteria,1NF98@1224|Proteobacteria,2UHG6@28211|Alphaproteobacteria,2JUK0@204441|Rhodospirillales	204441|Rhodospirillales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS1_k127_7609876_1	595460.RRSWK_06755	4.335e-222	707.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
GDHHQS1_k127_7609876_0	504472.Slin_6449	7.523e-301	941.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,47P0Q@768503|Cytophagia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
GDHHQS1_k127_7702912_5	1123274.KB899413_gene790	1.712e-35	140.0	COG0303@1|root,COG0303@2|Bacteria,2J7HN@203691|Spirochaetes	203691|Spirochaetes	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS1_k127_7702912_1	760568.Desku_2677	3.713e-89	304.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,260P7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GDHHQS1_k127_7702912_6	667014.Thein_0010	2.557e-31	130.0	COG0315@1|root,COG0315@2|Bacteria,2GHHH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS1_k127_7702912_2	1123489.AUAN01000012_gene1423	3.226e-53	191.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,4H4N0@909932|Negativicutes	909932|Negativicutes	H	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
GDHHQS1_k127_7702912_4	1089553.Tph_c08360	5.835e-47	173.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
GDHHQS1_k127_7702912_0	1227739.Hsw_4060	3.48e-142	461.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
GDHHQS1_k127_7702912_3	1267533.KB906738_gene2187	1.693e-52	190.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS1_k127_7702912_7	1267533.KB906738_gene2186	2.826e-09	63.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
GDHHQS1_k127_7721193_5	314278.NB231_15293	0.0004221	50.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1WXIA@135613|Chromatiales	135613|Chromatiales	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS1_k127_7721193_2	1168034.FH5T_08475	3.398e-26	126.0	COG2133@1|root,COG2911@1|root,COG3227@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PATR,Peptidase_M43,fn3
GDHHQS1_k127_7721193_4	1265503.KB905160_gene2819	3.519e-07	64.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	4.2.2.23	ko:K06972,ko:K18195	-	-	-	-	ko00000,ko01000,ko01002	-	PL4	-	Autotransporter,CBM-like,DUF285,Flg_new,SLH,fn3_3
GDHHQS1_k127_7721193_0	344747.PM8797T_20758	2.22e-129	428.0	COG2610@1|root,COG2610@2|Bacteria,2J1TI@203682|Planctomycetes	203682|Planctomycetes	EG	COG2610 H gluconate symporter and related permeases	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
GDHHQS1_k127_7721193_1	234267.Acid_7008	3.179e-96	322.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_7729719_2	768672.Desfe_0119	2.319e-20	97.0	arCOG04797@1|root,arCOG04797@2157|Archaea,2XS23@28889|Crenarchaeota	28889|Crenarchaeota	S	retrograde transport, endosome to Golgi	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7729719_0	870187.Thini_3502	7.933e-118	391.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,45ZVT@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS1_k127_7729719_3	311424.DhcVS_1093	1.782e-18	88.0	2A4E9@1|root,2ZJRI@2|Bacteria,2GAVU@200795|Chloroflexi,34DG2@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7729719_4	1041930.Mtc_0756	1.797e-10	64.0	COG0209@1|root,arCOG03713@1|root,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,2NAJJ@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
GDHHQS1_k127_7729719_1	1123371.ATXH01000001_gene1199	2.904e-27	111.0	COG0209@1|root,COG1594@1|root,COG0209@2|Bacteria,COG1594@2|Bacteria,2GH8M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Ribonucleotide reductase, all-alpha domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GDHHQS1_k127_7734495_2	706587.Desti_3662	9.301e-14	73.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,42WDP@68525|delta/epsilon subdivisions,2WRK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS1_k127_7734495_0	351627.Csac_2721	8.081e-211	680.0	COG5652@1|root,COG5652@2|Bacteria,1VR6Y@1239|Firmicutes,25F71@186801|Clostridia	186801|Clostridia	S	PFAM Heparinase II III family protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
GDHHQS1_k127_7734495_1	1122179.KB890436_gene1449	2.957e-28	117.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1IW1W@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_7740507_7	1504319.GM45_1625	7.476e-11	74.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,3UX1B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	femX	-	2.3.2.10	ko:K05363,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08779	RC00055,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
GDHHQS1_k127_7740507_4	933262.AXAM01000037_gene876	1.102e-23	104.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2MP8W@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS1_k127_7740507_6	1122621.ATZA01000022_gene1523	1.709e-19	96.0	COG0110@1|root,COG0110@2|Bacteria,4NMHW@976|Bacteroidetes,1IQY3@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (isoleucine patch	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GDHHQS1_k127_7740507_2	555779.Dthio_PD2719	2.006e-36	143.0	COG5017@1|root,COG5017@2|Bacteria,1MZGV@1224|Proteobacteria,432TQ@68525|delta/epsilon subdivisions,2WXT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
GDHHQS1_k127_7740507_3	555779.Dthio_PD2718	8.275e-35	138.0	COG0707@1|root,COG0707@2|Bacteria,1RJH9@1224|Proteobacteria,432J5@68525|delta/epsilon subdivisions,2WYGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Oligosaccharide biosynthesis protein Alg14 like	-	-	-	-	-	-	-	-	-	-	-	-	Alg14
GDHHQS1_k127_7740507_0	222534.KB893670_gene3884	2.531e-79	278.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4ESIU@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_trans_2_3,Glycos_transf_2
GDHHQS1_k127_7740507_1	391595.RLO149_p630440	6.63e-77	269.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria,2P3NR@2433|Roseobacter	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
GDHHQS1_k127_7740507_5	479434.Sthe_2271	1.321e-21	104.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS1_k127_7753240_3	237368.SCABRO_03146	5.129e-16	80.0	2EMFR@1|root,33F4G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7753240_5	933262.AXAM01000190_gene580	9.657e-12	66.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2WS3K@28221|Deltaproteobacteria,2MKVT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS1_k127_7753240_6	111780.Sta7437_3149	1.974e-08	58.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,3VNHG@52604|Pleurocapsales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS1_k127_7753240_1	1121335.Clst_0793	3.445e-38	149.0	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia	186801|Clostridia	G	YhcH YjgK YiaL family	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
GDHHQS1_k127_7753240_4	351627.Csac_1696	2.67e-14	77.0	COG1708@1|root,COG1708@2|Bacteria,1VIRD@1239|Firmicutes,24S99@186801|Clostridia,42HD3@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS1_k127_7753240_2	933262.AXAM01000092_gene2933	1.413e-26	113.0	COG2250@1|root,COG2250@2|Bacteria,1NHKB@1224|Proteobacteria,42Y2D@68525|delta/epsilon subdivisions,2WSZF@28221|Deltaproteobacteria,2MPE0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_7753240_0	269800.Tfu_0861	6.802e-121	400.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4EI01@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
GDHHQS1_k127_7785329_4	96561.Dole_2561	8.874e-05	46.0	2C60Y@1|root,32YTG@2|Bacteria,1NCUM@1224|Proteobacteria,4304V@68525|delta/epsilon subdivisions,2WVCB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7785329_0	700598.Niako_1749	1.141e-47	181.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
GDHHQS1_k127_7785329_3	530564.Psta_0855	2.911e-17	92.0	COG1082@1|root,COG1082@2|Bacteria,2J52H@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_7785329_2	886293.Sinac_6034	1.431e-34	139.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	2.3.2.29,2.5.1.18,3.8.1.2	ko:K00799,ko:K01560,ko:K09705,ko:K21420	ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418	-	R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905	RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
GDHHQS1_k127_7785329_1	639030.JHVA01000001_gene427	1.146e-37	151.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia	204432|Acidobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS1_k127_7803328_1	1120968.AUBX01000001_gene2225	3.718e-121	399.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47U3H@768503|Cytophagia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_7803328_0	1122605.KB893625_gene2136	4.03e-169	543.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1IWFX@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS1_k127_7825421_1	1122947.FR7_4292	4.105e-22	101.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,4H31M@909932|Negativicutes	909932|Negativicutes	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_8,RnfC_N,SLBB
GDHHQS1_k127_7825421_0	1047013.AQSP01000119_gene1318	2.322e-61	217.0	COG4843@1|root,COG4843@2|Bacteria,2NPKB@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
GDHHQS1_k127_7835372_2	376686.Fjoh_2456	1.75e-09	70.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7835372_1	1121904.ARBP01000025_gene6085	2.397e-36	156.0	COG2273@1|root,COG2730@1|root,COG3291@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	chiA	-	3.2.1.4,3.2.1.73,3.2.1.80	ko:K01179,ko:K01216,ko:K03332,ko:K20276	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R00879,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM_6,CHU_C,F5_F8_type_C,Glyco_hydro_16,PKD
GDHHQS1_k127_7835372_0	335543.Sfum_2837	1.333e-84	299.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42QA2@68525|delta/epsilon subdivisions,2X7QC@28221|Deltaproteobacteria,2MQRX@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS_9
GDHHQS1_k127_7838255_3	1220589.CD32_15935	5.55e-31	124.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3IWVE@400634|Lysinibacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS1_k127_7838255_6	1173264.KI913949_gene3115	1.943e-19	91.0	2E5P1@1|root,330DP@2|Bacteria,1G9FB@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS1_k127_7838255_5	1292035.H476_2819	4.165e-21	97.0	COG1396@1|root,COG1396@2|Bacteria,1U5FK@1239|Firmicutes,25JSZ@186801|Clostridia,25U3C@186804|Peptostreptococcaceae	186801|Clostridia	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS1_k127_7838255_0	247490.KSU1_C0978	1.406e-236	755.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
GDHHQS1_k127_7838255_1	1142394.PSMK_24160	1.143e-171	568.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS1_k127_7838255_4	96561.Dole_0165	1.207e-21	102.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,433D2@68525|delta/epsilon subdivisions,2WY7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
GDHHQS1_k127_7838255_2	398767.Glov_0178	1.179e-49	181.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42S1Y@68525|delta/epsilon subdivisions,2WP4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	AraC-type transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
GDHHQS1_k127_7883210_1	604331.AUHY01000007_gene716	2.407e-23	112.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	algG	-	5.1.3.37	ko:K01795	ko00051,map00051	-	R08693	RC00509	ko00000,ko00001,ko01000	-	-	-	Beta_helix,DUF1565,NosD
GDHHQS1_k127_7883210_0	595460.RRSWK_06279	1.74e-108	364.0	COG0480@1|root,COG0480@2|Bacteria,2IX5V@203682|Planctomycetes	203682|Planctomycetes	J	COG0480 Translation elongation factors	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS1_k127_7891461_0	243090.RB6221	2.24e-191	612.0	COG5549@1|root,COG5549@2|Bacteria,2IXDX@203682|Planctomycetes	203682|Planctomycetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
GDHHQS1_k127_7891461_1	243090.RB1828	1.581e-133	435.0	COG3540@1|root,COG3540@2|Bacteria,2J1R1@203682|Planctomycetes	203682|Planctomycetes	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_790364_1	243090.RB4846	1.487e-87	310.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GDHHQS1_k127_790364_0	452637.Oter_3513	3.79e-138	452.0	COG0673@1|root,COG0673@2|Bacteria,46ZKA@74201|Verrucomicrobia,3K93V@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_790364_2	1403819.BATR01000090_gene2633	5.976e-79	272.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
GDHHQS1_k127_790364_3	497964.CfE428DRAFT_6475	2.457e-11	74.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia	2|Bacteria	G	Domain of Unknown Function (DUF1080)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
GDHHQS1_k127_7918379_2	452637.Oter_2975	2.132e-71	245.0	COG0673@1|root,COG0673@2|Bacteria,46UJ9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_7918379_1	479434.Sthe_1513	8.573e-86	306.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YYI@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS1_k127_7918379_4	335541.Swol_1076	5.122e-47	193.0	COG5492@1|root,COG5492@2|Bacteria,1V7TS@1239|Firmicutes,25F4B@186801|Clostridia,42KX4@68298|Syntrophomonadaceae	2|Bacteria	N	Surface proteins containing Ig-like domains-like	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Flg_new,Glug,SLH
GDHHQS1_k127_7918379_0	880073.Calab_1263	1.544e-167	543.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_7918379_3	338969.Rfer_0258	2.053e-66	239.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2WEWP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS1_k127_7918379_6	1167006.UWK_00564	3.887e-24	119.0	2ENA5@1|root,33FXV@2|Bacteria,1P5GM@1224|Proteobacteria,432FV@68525|delta/epsilon subdivisions,2WX6T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_7918379_5	880073.Calab_1269	3.137e-24	116.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_7918379_7	880073.Calab_1268	0.0001101	52.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
GDHHQS1_k127_7932502_3	1121952.ATXT01000001_gene1210	7.069e-17	87.0	COG0558@1|root,COG0558@2|Bacteria,2GN3C@201174|Actinobacteria,4FKEI@85023|Microbacteriaceae	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GDHHQS1_k127_7932502_4	1321773.HMPREF9069_01396	1.864e-15	90.0	COG2244@1|root,COG2244@2|Bacteria,2IE8H@201174|Actinobacteria,4CXTX@84998|Coriobacteriia	84998|Coriobacteriia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GDHHQS1_k127_7932502_0	595460.RRSWK_05130	1.67e-79	285.0	COG0438@1|root,COG0472@1|root,COG0438@2|Bacteria,COG0472@2|Bacteria,2IXRB@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_7932502_2	243090.RB1900	1.962e-17	90.0	COG0250@1|root,COG0250@2|Bacteria,2J0E8@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
GDHHQS1_k127_7932502_1	1297742.A176_03390	1.774e-67	257.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2YTU8@29|Myxococcales	28221|Deltaproteobacteria	D	protein involved in exopolysaccharide biosynthesis	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
GDHHQS1_k127_7932502_5	373903.Hore_22210	1.098e-06	57.0	COG1596@1|root,COG1596@2|Bacteria,1V7F2@1239|Firmicutes,24TC2@186801|Clostridia,3WAXC@53433|Halanaerobiales	186801|Clostridia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS1_k127_7938452_3	1232437.KL661985_gene3579	4.363e-23	108.0	COG0494@1|root,COG0494@2|Bacteria,1Q5JU@1224|Proteobacteria,42RPC@68525|delta/epsilon subdivisions,2WNUK@28221|Deltaproteobacteria,2MJX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS1_k127_7938452_1	1499967.BAYZ01000171_gene5584	1.064e-113	377.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS1_k127_7938452_2	1192034.CAP_3819	1.044e-73	265.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
GDHHQS1_k127_7938452_0	368408.Tpen_1559	9.936e-118	389.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_794823_2	1210884.HG799471_gene14621	5.376e-126	414.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GDHHQS1_k127_794823_1	886293.Sinac_5718	6.46e-181	578.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS1_k127_794823_0	313628.LNTAR_12216	3.139e-231	760.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_7997177_0	59374.Fisuc_2588	2.083e-49	190.0	2C7PP@1|root,33K9Q@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
GDHHQS1_k127_7997177_1	1122609.AUGT01000008_gene2868	2.162e-36	160.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
GDHHQS1_k127_7997177_2	59374.Fisuc_2002	1.246e-11	79.0	COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Laminin_G_3,fn3
GDHHQS1_k127_8013317_1	714313.LSA_06580	1.061e-97	334.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS1_k127_8013317_3	1411123.JQNH01000001_gene2315	2.052e-12	70.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS1_k127_8013317_0	497964.CfE428DRAFT_1475	3.3e-207	665.0	COG3525@1|root,COG3525@2|Bacteria,46SS5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
GDHHQS1_k127_8013317_2	714943.Mucpa_2861	1.134e-73	258.0	COG0775@1|root,COG0775@2|Bacteria,4NMPF@976|Bacteroidetes,1IZ9C@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphorylase superfamily	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS1_k127_8013317_4	1479235.KK366039_gene793	1.197e-08	58.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1XI24@135619|Oceanospirillales	135619|Oceanospirillales	S	Permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
GDHHQS1_k127_8063608_0	237368.SCABRO_01711	6.106e-37	153.0	COG1533@1|root,COG1533@2|Bacteria,2J47J@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase activity	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS1_k127_8127888_1	1499967.BAYZ01000040_gene2240	1.25e-53	192.0	COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
GDHHQS1_k127_8127888_2	309803.CTN_1854	2.225e-50	183.0	COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae	200918|Thermotogae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS1_k127_8127888_0	385682.AFSL01000012_gene2848	1.862e-97	332.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes,2FPSM@200643|Bacteroidia	976|Bacteroidetes	S	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
GDHHQS1_k127_8140811_1	1267535.KB906767_gene232	9.441e-72	255.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874,Glyco_hydro_42
GDHHQS1_k127_8140811_3	237368.SCABRO_03851	4.083e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_8140811_0	497964.CfE428DRAFT_5426	5.042e-75	265.0	COG1680@1|root,COG1680@2|Bacteria,46WGY@74201|Verrucomicrobia	74201|Verrucomicrobia	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8140811_2	143224.JQMD01000002_gene3619	3.19e-52	191.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1HYF8@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
GDHHQS1_k127_8191707_2	1415774.U728_601	6.928e-13	80.0	COG0477@1|root,COG2814@2|Bacteria,1UJ0G@1239|Firmicutes,24BM5@186801|Clostridia,36FVJ@31979|Clostridiaceae	186801|Clostridia	EGP	MFS/sugar transport protein	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
GDHHQS1_k127_8191707_0	1123020.AUIE01000007_gene3427	3.919e-17	88.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,1YCT8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS1_k127_8191707_3	886293.Sinac_4705	1.759e-06	59.0	COG2834@1|root,COG2834@2|Bacteria,2J4MG@203682|Planctomycetes	203682|Planctomycetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8191707_1	1192034.CAP_0295	1.025e-14	81.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_8220816_0	933262.AXAM01000042_gene1835	6.639e-153	491.0	COG1032@1|root,COG1032@2|Bacteria,1NRWP@1224|Proteobacteria,42S72@68525|delta/epsilon subdivisions,2WNA6@28221|Deltaproteobacteria,2MKAP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS1_k127_8220816_4	1198232.CYCME_0687	7.78e-11	72.0	COG0515@1|root,COG0515@2|Bacteria,1MXX9@1224|Proteobacteria,1RQFJ@1236|Gammaproteobacteria,4629K@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core	-	-	-	ko:K02848	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Kdo
GDHHQS1_k127_8220816_2	1210884.HG799465_gene11570	3.335e-33	143.0	COG0438@1|root,COG0438@2|Bacteria,2IZ1G@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS1_k127_8220816_1	1396418.BATQ01000142_gene3282	9.13e-40	158.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS1_k127_8220816_3	794903.OPIT5_20185	9.435e-12	77.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS1_k127_8220816_5	314230.DSM3645_11626	3.153e-05	47.0	COG1943@1|root,COG1943@2|Bacteria,2J16A@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS1_k127_822264_3	1242864.D187_003825	8.141e-16	87.0	COG0667@1|root,COG0667@2|Bacteria,1QJYC@1224|Proteobacteria,42QD6@68525|delta/epsilon subdivisions,2WJ6W@28221|Deltaproteobacteria,2Z31C@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS1_k127_822264_1	909663.KI867151_gene3160	5.282e-81	274.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria,2MRK4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS1_k127_822264_0	909663.KI867151_gene3159	4.565e-84	315.0	COG2202@1|root,COG4191@1|root,COG4585@1|root,COG5001@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21084	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,dCache_1
GDHHQS1_k127_822264_2	909663.KI867150_gene703	6.802e-59	234.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,43BSA@68525|delta/epsilon subdivisions,2X860@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10,PAS_3,PAS_9
GDHHQS1_k127_8262538_1	1195236.CTER_4883	4.083e-87	315.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
GDHHQS1_k127_8262538_0	1158294.JOMI01000004_gene3543	1.465e-131	446.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,2FSDK@200643|Bacteroidia	976|Bacteroidetes	G	SMP-30 Gluconolaconase LRE-like	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
GDHHQS1_k127_8262538_2	344747.PM8797T_17202	1.64e-85	295.0	COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8304968_0	344747.PM8797T_26260	7.742e-263	835.0	COG0249@1|root,COG0249@2|Bacteria,2IXGV@203682|Planctomycetes	203682|Planctomycetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS1_k127_8304968_3	671143.DAMO_1705	8.594e-19	89.0	COG1708@1|root,COG1708@2|Bacteria,2NRXI@2323|unclassified Bacteria	2|Bacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
GDHHQS1_k127_8304968_2	671143.DAMO_1706	1.741e-19	93.0	COG2250@1|root,COG2250@2|Bacteria,2NRCJ@2323|unclassified Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS1_k127_8304968_1	338966.Ppro_3278	1.252e-104	346.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,43TIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS1_k127_830676_1	326427.Cagg_0452	2.089e-46	168.0	COG0270@1|root,COG0270@2|Bacteria,2GB4Y@200795|Chloroflexi,3779P@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
GDHHQS1_k127_830676_3	938288.HG326224_gene1560	2.538e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS1_k127_830676_0	1379698.RBG1_1C00001G1160	2.446e-222	709.0	COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria	2|Bacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS1_k127_830676_2	575540.Isop_3481	1.356e-38	153.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	atoS	-	2.7.13.3	ko:K02482,ko:K07709,ko:K07710	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_8,PAS_9
GDHHQS1_k127_8319780_5	926569.ANT_16650	3.212e-15	76.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS1_k127_8319780_0	1521187.JPIM01000015_gene3733	1.566e-117	396.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia	32061|Chloroflexia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS1_k127_8319780_2	429009.Adeg_0594	2.687e-68	237.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,42EVI@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM GTP cyclohydrolase I Nitrile oxidoreductase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS1_k127_8319780_3	1234664.AMRO01000077_gene3383	4.372e-34	141.0	COG0720@1|root,COG0720@2|Bacteria,1UZVB@1239|Firmicutes,4H9SV@91061|Bacilli,1WHII@129337|Geobacillus	91061|Bacilli	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS1_k127_8319780_1	1499967.BAYZ01000195_gene3101	1.473e-109	363.0	COG0451@1|root,COG0451@2|Bacteria,2NP15@2323|unclassified Bacteria	2|Bacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	arnA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315	1.1.1.305,2.1.2.13,5.1.3.2	ko:K01784,ko:K10011,ko:K12449	ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503	M00361,M00362,M00632,M00721,M00761	R00291,R01384,R01386,R02984,R07658,R07660	RC00026,RC00289,RC00508,RC01575,RC01811,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO2420,iSFV_1184.SFV_2325	Epimerase,Formyl_trans_C,Formyl_trans_N,GDP_Man_Dehyd
GDHHQS1_k127_8319780_4	1047013.AQSP01000133_gene2141	6.171e-21	98.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
GDHHQS1_k127_8344867_1	278957.ABEA03000174_gene3362	2.923e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_8344867_0	1232410.KI421412_gene435	4.689e-57	203.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,43TSZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
GDHHQS1_k127_8378456_2	595460.RRSWK_06547	3.208e-08	59.0	COG0597@1|root,COG0597@2|Bacteria,2J0RI@203682|Planctomycetes	203682|Planctomycetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS1_k127_8378456_0	755731.Clo1100_2703	9.359e-182	584.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,36EXB@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GDHHQS1_k127_8378456_1	1173264.KI913949_gene2873	4.162e-48	181.0	COG4185@1|root,COG4185@2|Bacteria,1G56J@1117|Cyanobacteria,1HBQZ@1150|Oscillatoriales	1117|Cyanobacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
GDHHQS1_k127_8428083_1	671143.DAMO_1640	1.519e-36	149.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02841,ko:K02843,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS1_k127_8428083_0	1094980.Mpsy_0698	2.39e-214	676.0	COG0058@1|root,arCOG01421@2157|Archaea,2XV8J@28890|Euryarchaeota,2NACZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS1_k127_8444506_1	1173264.KI913949_gene941	2.142e-57	205.0	COG0018@1|root,COG0018@2|Bacteria,1G15V@1117|Cyanobacteria,1H7AH@1150|Oscillatoriales	1117|Cyanobacteria	J	Arginyl tRNA synthetase N terminal domain	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS1_k127_8444506_2	555079.Toce_0771	2.123e-29	121.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,42H2X@68295|Thermoanaerobacterales	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS1_k127_8444506_0	1408473.JHXO01000006_gene1341	7.879e-304	947.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
GDHHQS1_k127_8498996_6	247490.KSU1_C1462	5.329e-05	50.0	2EWE5@1|root,33PSP@2|Bacteria,2J1V0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8498996_0	1227454.C446_05270	1.588e-38	154.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XSW9@28890|Euryarchaeota,23T65@183963|Halobacteria	183963|Halobacteria	GH	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P,NAD_kinase
GDHHQS1_k127_8498996_5	1142394.PSMK_02520	6.088e-06	55.0	2E3B2@1|root,32YAK@2|Bacteria,2J19J@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
GDHHQS1_k127_8498996_2	880070.Cycma_0728	8.671e-16	92.0	COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria,4NPXZ@976|Bacteroidetes,47S50@768503|Cytophagia	976|Bacteroidetes	N	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_lyase
GDHHQS1_k127_8498996_1	1121403.AUCV01000058_gene3038	7.717e-18	98.0	COG1520@1|root,COG3866@1|root,COG1520@2|Bacteria,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CHU_C,DUF285,HYR,fn3
GDHHQS1_k127_8498996_3	153721.MYP_2112	1.307e-09	71.0	COG3405@1|root,COG3405@2|Bacteria,4NIN5@976|Bacteroidetes,47MQ6@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM9_1,Glyco_hydro_8
GDHHQS1_k127_8498996_4	1121285.AUFK01000009_gene1148	7.925e-07	62.0	COG4733@1|root,COG4733@2|Bacteria,4PKYK@976|Bacteroidetes,1IJHK@117743|Flavobacteriia,3ZQWF@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Pec_lyase_C,fn3
GDHHQS1_k127_8503390_6	880070.Cycma_0162	3.746e-49	182.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_8503390_4	1125863.JAFN01000001_gene1785	3.711e-65	227.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
GDHHQS1_k127_8503390_3	880073.Calab_1856	1.29e-78	275.0	COG0012@1|root,COG0012@2|Bacteria,2NNNF@2323|unclassified Bacteria	2|Bacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS1_k127_8503390_2	323261.Noc_0828	2.761e-86	294.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,1WXPE@135613|Chromatiales	135613|Chromatiales	O	PFAM Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
GDHHQS1_k127_8503390_0	1047013.AQSP01000142_gene235	2.824e-122	401.0	COG1063@1|root,COG1063@2|Bacteria,2NPFX@2323|unclassified Bacteria	2|Bacteria	E	Glucose dehydrogenase C-terminus	ydjJ	-	1.1.1.14,1.1.1.9	ko:K00008,ko:K05351	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS1_k127_8503390_1	697303.Thewi_0309	6.495e-95	318.0	COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,24AFI@186801|Clostridia	186801|Clostridia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.140	ko:K00068	ko00051,map00051	-	R05607	RC00085	ko00000,ko00001,ko01000	-	-	-	adh_short
GDHHQS1_k127_8503390_5	583355.Caka_0705	7.847e-63	220.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_853366_1	313628.LNTAR_12566	4.708e-36	151.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GDHHQS1_k127_853366_0	545694.TREPR_0418	1.999e-67	239.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
GDHHQS1_k127_853366_2	344747.PM8797T_00397	1.39e-08	65.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
GDHHQS1_k127_8637977_0	1142394.PSMK_18100	1.314e-63	225.0	COG0740@1|root,COG0740@2|Bacteria,2IYFK@203682|Planctomycetes	203682|Planctomycetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS1_k127_8637977_1	344747.PM8797T_25511	6.402e-61	231.0	COG0544@1|root,COG0544@2|Bacteria,2IXGD@203682|Planctomycetes	203682|Planctomycetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
GDHHQS1_k127_8640956_2	411902.CLOBOL_04851	1.371e-50	187.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,21XGP@1506553|Lachnoclostridium	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS1_k127_8640956_0	243090.RB940	1.844e-217	686.0	COG3386@1|root,COG3386@2|Bacteria,2J2MK@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
GDHHQS1_k127_8640956_3	665571.STHERM_c04330	8.741e-22	106.0	COG0800@1|root,COG0800@2|Bacteria,2J6B8@203691|Spirochaetes	203691|Spirochaetes	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS1_k127_8640956_1	278957.ABEA03000193_gene1036	6.112e-86	291.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS1_k127_8640956_4	443143.GM18_0019	2.557e-05	46.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
GDHHQS1_k127_8681101_1	1379281.AVAG01000026_gene1616	1.99e-146	475.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2M88B@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
GDHHQS1_k127_8681101_2	1168034.FH5T_18825	2.192e-24	113.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	mpaA	GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K14054	-	-	-	-	ko00000	-	-	iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491	Peptidase_M14
GDHHQS1_k127_8681101_0	530564.Psta_4250	8.567e-152	486.0	COG0556@1|root,COG0556@2|Bacteria,2IWS1@203682|Planctomycetes	203682|Planctomycetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS1_k127_8695231_2	237368.SCABRO_00123	7.832e-18	84.0	COG3225@1|root,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
GDHHQS1_k127_8695231_0	237368.SCABRO_00124	5.355e-122	394.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5,ABC_transp_aux
GDHHQS1_k127_8695231_1	237368.SCABRO_00125	6.746e-122	395.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS1_k127_8708760_0	247490.KSU1_D0387	5.947e-184	583.0	COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes	203682|Planctomycetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS1_k127_8708760_1	1303518.CCALI_02044	1.391e-142	462.0	2EE91@1|root,3383F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8708760_2	485918.Cpin_6423	0.000146	48.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_8711282_2	1280692.AUJL01000006_gene1502	5.857e-24	104.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,36E1B@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
GDHHQS1_k127_8711282_1	1048834.TC41_0900	6.57e-25	118.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli	91061|Bacilli	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	-	-	2.7.1.11,2.7.1.56	ko:K00882,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R02071,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS1_k127_8711282_0	756272.Plabr_3033	5.303e-138	448.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Metallophos,Pur_ac_phosph_N
GDHHQS1_k127_8722455_0	246969.TAM4_1544	5.271e-70	254.0	COG3839@1|root,arCOG00175@2157|Archaea,2Y7MN@28890|Euryarchaeota,245BN@183968|Thermococci	183968|Thermococci	E	TOBE domain	-	-	3.6.3.55	ko:K15497	ko02010,map02010	M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5	-	-	ABC_tran,TOBE
GDHHQS1_k127_8722455_1	1123070.KB899258_gene1896	9.372e-55	205.0	COG0555@1|root,COG0555@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	modB1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
GDHHQS1_k127_8722455_2	565045.NOR51B_1366	8.366e-14	75.0	29C5B@1|root,2ZZ3W@2|Bacteria,1MYZM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_8734720_1	671143.DAMO_0214	1.588e-30	128.0	COG1572@1|root,COG1572@2|Bacteria,2NRGM@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,CARDB,CHU_C,Calx-beta,DUF4091,F5_F8_type_C,G5,Gram_pos_anchor,PPC,Trypsin_2,YSIRK_signal
GDHHQS1_k127_8734720_2	754436.JCM19237_117	1.249e-23	117.0	COG2304@1|root,COG5183@1|root,COG2304@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1XVD5@135623|Vibrionales	135623|Vibrionales	A	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TSP_3
GDHHQS1_k127_8734720_3	760192.Halhy_5276	5.523e-17	96.0	COG3934@1|root,COG3934@2|Bacteria,4NJJS@976|Bacteroidetes	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF5060
GDHHQS1_k127_8734720_0	247490.KSU1_C0729	4.509e-68	241.0	COG0616@1|root,COG0616@2|Bacteria,2IYKF@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS1_k127_8745127_0	1047013.AQSP01000133_gene2141	4.784e-237	752.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
GDHHQS1_k127_8745127_1	309807.SRU_2090	0.0006758	51.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,1FIYK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS1_k127_8772834_0	1499967.BAYZ01000156_gene565	4.346e-48	176.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS1_k127_8772834_1	1260251.SPISAL_00785	2.3e-21	102.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
GDHHQS1_k127_8772834_2	498848.TaqDRAFT_3998	3.713e-05	54.0	COG1082@1|root,COG1082@2|Bacteria,1WI0M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_8903129_1	386456.JQKN01000001_gene1802	2.338e-65	236.0	COG0642@1|root,COG3413@1|root,arCOG02348@1|root,arCOG02350@1|root,arCOG03567@1|root,arCOG06712@1|root,arCOG02278@2157|Archaea,arCOG02348@2157|Archaea,arCOG02350@2157|Archaea,arCOG02358@2157|Archaea,arCOG03567@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,HisKA_4TM,MEDS,PAS,PAS_3,PAS_4,PAS_9
GDHHQS1_k127_8903129_0	518766.Rmar_1734	1.72e-152	496.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1FJ32@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_890530_0	1313421.JHBV01000007_gene4258	4.12e-21	110.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,4NN8K@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1735)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Laminin_G_3
GDHHQS1_k127_8909789_4	595460.RRSWK_01782	1.702e-68	238.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS1_k127_8909789_5	886293.Sinac_1364	1.206e-25	108.0	COG0236@1|root,COG0236@2|Bacteria,2J0V5@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS1_k127_8909789_3	556261.HMPREF0240_00427	3.057e-73	254.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36EGR@31979|Clostridiaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS1_k127_8909789_2	756272.Plabr_2508	7.031e-84	289.0	COG0331@1|root,COG0331@2|Bacteria,2IXX2@203682|Planctomycetes	203682|Planctomycetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS1_k127_8909789_0	443144.GM21_1154	3.144e-106	354.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS1_k127_8909789_1	1142394.PSMK_17290	4.063e-89	305.0	COG0416@1|root,COG0416@2|Bacteria,2IWUY@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS1_k127_8909789_6	1142394.PSMK_17300	2.713e-08	57.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS1_k127_8966183_0	1396141.BATP01000003_gene4934	9.438e-98	357.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
GDHHQS1_k127_9033547_3	1121887.AUDK01000031_gene1036	8.861e-08	65.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9033547_2	1121904.ARBP01000025_gene6085	4.377e-38	162.0	COG2273@1|root,COG2730@1|root,COG3291@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	chiA	-	3.2.1.4,3.2.1.73,3.2.1.80	ko:K01179,ko:K01216,ko:K03332,ko:K20276	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R00879,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM_6,CHU_C,F5_F8_type_C,Glyco_hydro_16,PKD
GDHHQS1_k127_9033547_0	682795.AciX8_3506	1.022e-182	595.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glyco_hydro_42,Glycos_transf_2
GDHHQS1_k127_9033547_1	240016.ABIZ01000001_gene5946	1.211e-47	178.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS1_k127_9033730_1	1220583.GOACH_22_00080	0.0001093	55.0	2C9AC@1|root,2Z7TR@2|Bacteria,2I07F@201174|Actinobacteria,4GCVZ@85026|Gordoniaceae	201174|Actinobacteria	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
GDHHQS1_k127_9033730_0	1458357.BG58_15110	1.673e-86	300.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2VJ5N@28216|Betaproteobacteria,1K5Q5@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,GMC_oxred_C,GMC_oxred_N,Lactamase_B
GDHHQS1_k127_9067719_1	1232437.KL661985_gene3579	9.923e-09	59.0	COG0494@1|root,COG0494@2|Bacteria,1Q5JU@1224|Proteobacteria,42RPC@68525|delta/epsilon subdivisions,2WNUK@28221|Deltaproteobacteria,2MJX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS1_k127_9067719_0	1499967.BAYZ01000027_gene1815	6.044e-109	366.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS1_k127_9072407_3	756272.Plabr_1201	9.608e-48	186.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
GDHHQS1_k127_9072407_1	1089551.KE386572_gene298	6.63e-111	365.0	COG1082@1|root,COG1082@2|Bacteria,1QYE4@1224|Proteobacteria,2TXTQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_9072407_0	1410620.SHLA_36c000140	1.225e-145	466.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_9072407_2	314230.DSM3645_26609	1.469e-58	211.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
GDHHQS1_k127_9075397_2	457412.RSAG_02822	8.862e-46	183.0	COG2159@1|root,COG2159@2|Bacteria,1UZI6@1239|Firmicutes,24EHD@186801|Clostridia,3WKR9@541000|Ruminococcaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS1_k127_9075397_0	575540.Isop_1907	2.653e-101	336.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_9075397_1	553973.CLOHYLEM_07268	3.585e-49	186.0	COG1082@1|root,COG1082@2|Bacteria,1VRFT@1239|Firmicutes,24Z5T@186801|Clostridia,223EZ@1506553|Lachnoclostridium	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS1_k127_9082917_3	530564.Psta_0935	5.642e-14	75.0	COG1943@1|root,COG1943@2|Bacteria,2J370@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9082917_0	886293.Sinac_1310	7.077e-105	361.0	COG2812@1|root,COG2812@2|Bacteria,2IX1M@203682|Planctomycetes	203682|Planctomycetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS1_k127_9082917_2	592029.DDD_0379	1.97e-38	146.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes,1I4SZ@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS1_k127_9082917_4	1211817.CCAT010000046_gene2698	5.246e-13	72.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	fdx	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
GDHHQS1_k127_9082917_1	1149133.ppKF707_3296	3.123e-50	187.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1YF8Z@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
GDHHQS1_k127_9122660_0	931626.Awo_c12540	1.193e-40	159.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,25W0B@186806|Eubacteriaceae	186801|Clostridia	C	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS1_k127_9122660_1	373903.Hore_03970	1.452e-19	100.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WC1B@53433|Halanaerobiales	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS1_k127_9152288_0	935948.KE386493_gene2375	6.956e-12	76.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9159716_0	592031.GCWU000322_00643	1.832e-68	240.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,25URC@186806|Eubacteriaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS1_k127_9159716_1	546274.EIKCOROL_01227	1.433e-47	189.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KQII@206351|Neisseriales	206351|Neisseriales	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS1_k127_9159716_2	935948.KE386495_gene2134	1.085e-36	144.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS1_k127_9189375_4	7234.FBpp0180165	0.0004026	45.0	28WFT@1|root,2R37V@2759|Eukaryota,3ABHU@33154|Opisthokonta,3BVM7@33208|Metazoa,3DCPN@33213|Bilateria,42A22@6656|Arthropoda,3SNNE@50557|Insecta,451PU@7147|Diptera,45SGF@7214|Drosophilidae	33208|Metazoa	S	Centrosome-associated C terminus	-	-	-	-	-	-	-	-	-	-	-	-	FAM110_C
GDHHQS1_k127_9189375_5	1121923.GPUN_2598	0.0004208	52.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	cvaB	-	-	ko:K06147,ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding
GDHHQS1_k127_9189375_2	794903.OPIT5_17425	2.555e-09	67.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_9189375_3	1517682.HW49_00500	4.523e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,2FNJV@200643|Bacteroidia,22W2N@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS1_k127_9189375_1	1122225.AULQ01000005_gene2542	3.469e-41	174.0	COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
GDHHQS1_k127_9189375_0	1121405.dsmv_3144	3.194e-55	209.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MIFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS1_k127_9196090_2	1261545.MBE-HAL_0989	0.0003618	51.0	COG1637@1|root,arCOG01304@2157|Archaea,2XV87@28890|Euryarchaeota,23TK6@183963|Halobacteria	183963|Halobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
GDHHQS1_k127_9196090_0	56780.SYN_02176	2.458e-81	286.0	COG1032@1|root,COG1032@2|Bacteria,1R4XI@1224|Proteobacteria,42NPM@68525|delta/epsilon subdivisions,2WJK2@28221|Deltaproteobacteria,2MQ6Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS1_k127_9196090_1	1125701.HMPREF1221_01616	9.539e-34	145.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9244582_0	344747.PM8797T_19994	8.409e-141	459.0	COG5434@1|root,COG5434@2|Bacteria,2IX4E@203682|Planctomycetes	203682|Planctomycetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,Pectate_lyase_3
GDHHQS1_k127_9244582_2	886293.Sinac_6953	3.072e-105	360.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	203682|Planctomycetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_9244582_1	1122605.KB893648_gene3690	5.424e-136	451.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
GDHHQS1_k127_9294318_1	237368.SCABRO_00054	2.596e-28	123.0	COG1684@1|root,COG1684@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	fliR	-	-	ko:K02421,ko:K03228,ko:K13820	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_1
GDHHQS1_k127_9294318_0	639282.DEFDS_0413	8.549e-64	231.0	COG1377@1|root,COG1377@2|Bacteria,2GESV@200930|Deferribacteres	200930|Deferribacteres	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
GDHHQS1_k127_9294318_5	1521187.JPIM01000162_gene1304	0.0005437	49.0	2E747@1|root,331NN@2|Bacteria,2G9DK@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9294318_4	269799.Gmet_0074	0.0002798	45.0	COG3943@1|root,COG3943@2|Bacteria,1QY8E@1224|Proteobacteria	1224|Proteobacteria	S	COG3943, virulence protein	-	-	-	ko:K14623	-	-	-	-	ko00000,ko03400	-	-	-	-
GDHHQS1_k127_9370973_4	1123508.JH636441_gene3383	1.071e-16	81.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS1_k127_9370973_0	1047013.AQSP01000056_gene1922	0.0	1397.0	COG0841@1|root,COG0841@2|Bacteria,2NQKZ@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS1_k127_9370973_3	1047013.AQSP01000056_gene1921	2.625e-62	229.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS1_k127_9370973_2	666685.R2APBS1_2038	4.777e-88	308.0	COG1538@1|root,COG1538@2|Bacteria,1RFMJ@1224|Proteobacteria,1S8HY@1236|Gammaproteobacteria,1X7RA@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS1_k127_9370973_1	880073.Calab_1142	2.156e-230	721.0	COG1350@1|root,COG1350@2|Bacteria,2NNY3@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS1_k127_9370973_6	1515746.HR45_14445	3.576e-05	52.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,2Q8VA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
GDHHQS1_k127_9377024_3	313628.LNTAR_17443	4.84e-08	66.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,CBM_6,DUF1565,F5_F8_type_C,PEGA,Trypsin_2
GDHHQS1_k127_9377024_2	1122176.KB903559_gene4117	5.733e-13	83.0	COG1572@1|root,COG4675@1|root,COG4935@1|root,COG1572@2|Bacteria,COG4675@2|Bacteria,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1J10S@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
GDHHQS1_k127_9377024_0	886293.Sinac_2253	3.31e-152	497.0	COG1418@1|root,COG1418@2|Bacteria,2IX35@203682|Planctomycetes	203682|Planctomycetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS1_k127_9377024_1	349161.Dred_1917	8.046e-61	215.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
GDHHQS1_k127_9393803_1	1123508.JH636439_gene1727	1.065e-49	183.0	COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS1_k127_9393803_3	247490.KSU1_C1333	1.768e-09	68.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS1_k127_9393803_0	344747.PM8797T_26590	1.579e-105	355.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS1_k127_9393803_2	453591.Igni_0662	1.082e-21	103.0	COG1437@1|root,arCOG01723@2157|Archaea	2157|Archaea	F	adenylyl cyclase CyaB	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	CYTH
GDHHQS1_k127_9411565_1	595460.RRSWK_02559	3.294e-90	308.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
GDHHQS1_k127_9411565_2	525897.Dbac_2312	1.546e-14	79.0	COG3350@1|root,COG3350@2|Bacteria,1NE2T@1224|Proteobacteria,42VZQ@68525|delta/epsilon subdivisions,2WSDU@28221|Deltaproteobacteria,2MD4Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS1_k127_9411565_0	237368.SCABRO_01551	0.0	1538.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
GDHHQS1_k127_9441698_2	706587.Desti_3300	8.282e-33	129.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MQ9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS1_k127_9441698_1	118161.KB235922_gene2731	1.679e-46	183.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,3VM6G@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
GDHHQS1_k127_9441698_0	595460.RRSWK_02095	1.394e-191	604.0	COG4146@1|root,COG4146@2|Bacteria,2J29I@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS1_k127_9480073_3	869213.JCM21142_72658	1.671e-43	166.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_9480073_1	1123248.KB893314_gene3673	1.908e-83	281.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,1IWFP@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS1_k127_9480073_2	926549.KI421517_gene1767	7.685e-78	279.0	COG3828@1|root,COG3828@2|Bacteria,4PNCT@976|Bacteroidetes,47NTF@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS1_k127_9480073_5	1173027.Mic7113_5193	3.1e-26	111.0	COG1669@1|root,COG1669@2|Bacteria,1G6K9@1117|Cyanobacteria,1HCSN@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS1_k127_9480073_0	519989.ECTPHS_13375	8.463e-98	330.0	COG3440@1|root,COG3440@2|Bacteria	2|Bacteria	V	regulation of methylation-dependent chromatin silencing	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2,SAD_SRA
GDHHQS1_k127_9480073_4	384765.SIAM614_31683	1.202e-37	144.0	COG0863@1|root,COG0863@2|Bacteria,1R4QN@1224|Proteobacteria,2UEGH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_N,N6_N4_Mtase
GDHHQS1_k127_9494922_2	1142394.PSMK_11760	1.016e-31	124.0	COG0211@1|root,COG0211@2|Bacteria,2J04T@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GDHHQS1_k127_9494922_0	247490.KSU1_C0154	2.503e-119	392.0	COG0536@1|root,COG0536@2|Bacteria,2IX0Z@203682|Planctomycetes	203682|Planctomycetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
GDHHQS1_k127_9494922_1	247490.KSU1_C0153	2.216e-41	162.0	COG1521@1|root,COG1521@2|Bacteria,2J0M0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS1_k127_9494922_3	338966.Ppro_3622	4.084e-06	56.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,43TPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS1_k127_9514773_1	1168034.FH5T_01595	5.841e-65	234.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS1_k127_9514773_0	595460.RRSWK_06227	6.609e-76	266.0	COG0657@1|root,COG0657@2|Bacteria,2J2MF@203682|Planctomycetes	203682|Planctomycetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS1_k127_9514773_4	1415778.JQMM01000001_gene736	8.218e-49	185.0	COG0515@1|root,COG0515@2|Bacteria,1RAG3@1224|Proteobacteria,1S4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
GDHHQS1_k127_9514773_5	247490.KSU1_D0636	2.907e-48	190.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS1_k127_9514773_3	177437.HRM2_45140	3.538e-58	214.0	COG1073@1|root,COG1073@2|Bacteria,1NEVB@1224|Proteobacteria,42W4K@68525|delta/epsilon subdivisions,2WRSK@28221|Deltaproteobacteria,2MN89@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9514773_6	330214.NIDE3825	5.41e-15	85.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
GDHHQS1_k127_9514773_2	886293.Sinac_5728	1.998e-59	214.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS1_k127_9521261_2	204669.Acid345_1944	2.889e-61	216.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
GDHHQS1_k127_9521261_1	869213.JCM21142_3900	2.657e-92	312.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS1_k127_9521261_0	56780.SYN_02461	2.111e-123	400.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,43B4N@68525|delta/epsilon subdivisions,2X6IA@28221|Deltaproteobacteria,2MSF8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS1_k127_952874_1	368408.Tpen_1559	3.425e-114	384.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_952874_0	472759.Nhal_3091	5.189e-197	635.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales	135613|Chromatiales	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS1_k127_9531530_1	1232410.KI421425_gene1568	1.497e-22	106.0	COG0484@1|root,COG0484@2|Bacteria,1NR5B@1224|Proteobacteria,42YEQ@68525|delta/epsilon subdivisions,2WTT6@28221|Deltaproteobacteria,43TYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9531530_4	1177928.TH2_05618	4.219e-09	68.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,2JPPX@204441|Rhodospirillales	204441|Rhodospirillales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
GDHHQS1_k127_9531530_0	768704.Desmer_3460	6.765e-56	202.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,24K8U@186801|Clostridia,262X7@186807|Peptococcaceae	186801|Clostridia	C	Cytochrome b subunit of the bc	-	-	-	ko:K00412,ko:K02635	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrome_B
GDHHQS1_k127_9531530_2	443143.GM18_0922	2.291e-19	94.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
GDHHQS1_k127_9531530_3	1125863.JAFN01000001_gene976	2.756e-12	78.0	COG0457@1|root,COG0457@2|Bacteria	1125863.JAFN01000001_gene976|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9531530_5	443143.GM18_1016	4.872e-05	46.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS1_k127_9532681_2	933262.AXAM01000022_gene3239	2.037e-30	121.0	2E9N9@1|root,333US@2|Bacteria,1NBXS@1224|Proteobacteria,431H2@68525|delta/epsilon subdivisions,2WX3H@28221|Deltaproteobacteria,2MNT1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9532681_1	1123242.JH636435_gene1842	1.003e-80	284.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GDHHQS1_k127_9532681_3	315750.BPUM_1394	2.622e-28	123.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS1_k127_9532681_0	643648.Slip_2150	1.768e-97	336.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,42KBK@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GDHHQS1_k127_9532844_3	755731.Clo1100_2482	7.073e-57	206.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,36ERV@31979|Clostridiaceae	186801|Clostridia	P	domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS1_k127_9532844_4	1128421.JAGA01000002_gene344	8.292e-47	176.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS1_k127_9532844_0	247490.KSU1_D1028	3.587e-172	563.0	COG1200@1|root,COG1200@2|Bacteria,2IX1Q@203682|Planctomycetes	203682|Planctomycetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS1_k127_9532844_5	237368.SCABRO_02363	5.92e-34	132.0	COG2827@1|root,COG2827@2|Bacteria,2J3VU@203682|Planctomycetes	203682|Planctomycetes	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
GDHHQS1_k127_9532844_1	161156.JQKW01000006_gene1394	1.482e-60	217.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS1_k127_9532844_2	1462526.BN990_02797	2.458e-58	209.0	COG0730@1|root,COG0730@2|Bacteria,1UCVY@1239|Firmicutes,4HG2T@91061|Bacilli	91061|Bacilli	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS1_k127_9555707_1	1121904.ARBP01000011_gene1522	1.019e-17	86.0	2DBP2@1|root,2ZA71@2|Bacteria,4NFFI@976|Bacteroidetes,47NDZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9555707_0	886293.Sinac_1932	2.943e-114	399.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS1_k127_9562035_9	573413.Spirs_1459	1.378e-27	114.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
GDHHQS1_k127_9562035_3	1123405.AUMM01000007_gene946	4.161e-80	274.0	2DUZH@1|root,33T6A@2|Bacteria,1VXYG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9562035_0	530564.Psta_4031	2.16e-182	582.0	COG0015@1|root,COG0015@2|Bacteria,2IXU4@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS1_k127_9562035_8	1142394.PSMK_29720	8.963e-41	156.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS1_k127_9562035_7	1121472.AQWN01000003_gene1427	4.08e-44	168.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25ZXR@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS1_k127_9562035_5	936573.HMPREF1147_0555	3.644e-49	182.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS1_k127_9562035_10	521674.Plim_2053	6.362e-12	68.0	COG1758@1|root,COG1758@2|Bacteria,2J0KS@203682|Planctomycetes	203682|Planctomycetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
GDHHQS1_k127_9562035_6	1321814.HMPREF9089_01131	1.664e-46	174.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,25WGB@186806|Eubacteriaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS1_k127_9562035_4	530564.Psta_3126	2.181e-59	216.0	COG1561@1|root,COG1561@2|Bacteria,2IYZH@203682|Planctomycetes	203682|Planctomycetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GDHHQS1_k127_9562035_11	344747.PM8797T_01619	1.236e-05	54.0	COG1314@1|root,COG1314@2|Bacteria,2J0NU@203682|Planctomycetes	203682|Planctomycetes	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS1_k127_9562035_2	756272.Plabr_4356	8.11e-81	278.0	COG0149@1|root,COG0149@2|Bacteria,2IXV9@203682|Planctomycetes	203682|Planctomycetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS1_k127_9562035_1	1142394.PSMK_11990	7.986e-128	418.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,2IWZ7@203682|Planctomycetes	203682|Planctomycetes	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
GDHHQS1_k127_9562035_12	1211777.BN77_1151	0.000838	46.0	COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2TV5U@28211|Alphaproteobacteria,4B9VJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
GDHHQS1_k127_9591009_0	756272.Plabr_1908	1.791e-125	413.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_9591009_1	272558.10174146	3.561e-81	280.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS1_k127_9609603_0	640513.Entas_3543	7.112e-06	48.0	COG0823@1|root,COG0823@2|Bacteria,1MUK9@1224|Proteobacteria,1RR42@1236|Gammaproteobacteria,3X1DB@547|Enterobacter	1236|Gammaproteobacteria	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
GDHHQS1_k127_9609603_1	696747.NIES39_B00450	0.0001286	52.0	COG0457@1|root,COG4421@1|root,COG0457@2|Bacteria,COG4421@2|Bacteria,1G2V7@1117|Cyanobacteria,1H9R5@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
GDHHQS1_k127_9615697_1	46234.ANA_C13788	5.254e-28	133.0	COG1404@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG3537@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,1G2N0@1117|Cyanobacteria,1HRSX@1161|Nostocales	1117|Cyanobacteria	GOQ	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF4347,HemolysinCabind,Laminin_G_3,SBP_bac_3,VCBS
GDHHQS1_k127_9615697_0	269798.CHU_1240	5.607e-35	156.0	COG0726@1|root,COG3405@1|root,COG0726@2|Bacteria,COG3405@2|Bacteria,4NIN5@976|Bacteroidetes,47MQ6@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM9_1,Glyco_hydro_8
GDHHQS1_k127_9615697_2	96561.Dole_1510	1.559e-10	68.0	COG0823@1|root,COG0823@2|Bacteria,1NR8W@1224|Proteobacteria,42YPB@68525|delta/epsilon subdivisions,2WTWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS1_k127_9623960_1	497965.Cyan7822_4673	7.657e-17	83.0	COG1028@1|root,COG1028@2|Bacteria,1G0MD@1117|Cyanobacteria,3KGZV@43988|Cyanothece	1117|Cyanobacteria	IQ	Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS1_k127_9623960_2	419665.Maeo_1250	2.323e-14	86.0	COG0666@1|root,arCOG04004@2157|Archaea,2Y1CJ@28890|Euryarchaeota,23RMT@183939|Methanococci	183939|Methanococci	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9623960_0	204669.Acid345_0040	8.093e-64	231.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria,2JHJB@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS1_k127_966058_4	204669.Acid345_0181	7.831e-26	114.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
GDHHQS1_k127_966058_1	1123242.JH636434_gene4078	1.13e-108	362.0	COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS1_k127_966058_0	1379698.RBG1_1C00001G0065	3.584e-248	786.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,GlcNAc_2-epim,Thioredox_DsbH
GDHHQS1_k127_966058_3	1280001.BAOA01000072_gene2766	6.367e-29	119.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1SAJ2@1236|Gammaproteobacteria,1XXUY@135623|Vibrionales	135623|Vibrionales	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
GDHHQS1_k127_966058_2	335543.Sfum_1822	5.932e-63	221.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MRHC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
GDHHQS1_k127_9719428_1	318161.Sden_1471	8.643e-12	72.0	293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9719428_0	1121904.ARBP01000009_gene4330	5.653e-297	934.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,47N3E@768503|Cytophagia	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GDHHQS1_k127_9720988_3	247490.KSU1_B0556	2.955e-77	266.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS1_k127_9720988_5	292563.Cyast_0391	2.543e-52	194.0	COG1043@1|root,COG1043@2|Bacteria,1G1V3@1117|Cyanobacteria	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN678.lpxA	Acetyltransf_11,Hexapep
GDHHQS1_k127_9720988_1	1142394.PSMK_05870	1.574e-130	430.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2IZ4S@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
GDHHQS1_k127_9720988_4	497964.CfE428DRAFT_4703	7.101e-59	218.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS1_k127_9720988_2	247490.KSU1_B0552	7.673e-82	306.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS1_k127_9720988_0	1142394.PSMK_13120	4.693e-139	456.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS1_k127_978340_2	1396141.BATP01000030_gene3773	8.624e-71	268.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
GDHHQS1_k127_978340_0	886293.Sinac_0949	9.968e-235	752.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
GDHHQS1_k127_978340_3	1142394.PSMK_18550	2.016e-44	175.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
GDHHQS1_k127_978340_4	1120973.AQXL01000105_gene2561	3.62e-35	141.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27A2H@186823|Alicyclobacillaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
GDHHQS1_k127_978340_1	1123508.JH636439_gene1006	4.504e-145	475.0	COG2256@1|root,COG2256@2|Bacteria,2IX8G@203682|Planctomycetes	203682|Planctomycetes	L	ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GDHHQS1_k127_9797276_4	411154.GFO_0240	3.732e-11	66.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS1_k127_9797276_0	1123373.ATXI01000009_gene372	4.468e-116	389.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS1_k127_9797276_2	767817.Desgi_2975	5.075e-35	139.0	COG1522@1|root,COG1522@2|Bacteria,1V6TK@1239|Firmicutes,24KE6@186801|Clostridia,2627S@186807|Peptococcaceae	186801|Clostridia	K	SMART Transcription regulator, AsnC-type	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
GDHHQS1_k127_9797276_3	880073.Calab_0422	2.271e-24	109.0	COG0745@1|root,COG0745@2|Bacteria,2NRCE@2323|unclassified Bacteria	2|Bacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS1_k127_9797276_1	880073.Calab_0423	4.409e-43	174.0	COG0642@1|root,COG2205@2|Bacteria	880073.Calab_0423|-	T	PhoQ Sensor	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
GDHHQS1_k127_9821762_1	344747.PM8797T_01824	1.452e-61	238.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GDHHQS1_k127_9821762_0	237368.SCABRO_03445	4.34e-115	381.0	COG1190@1|root,COG1190@2|Bacteria,2IXHX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS1_k127_9846899_0	237368.SCABRO_02550	5.654e-56	211.0	COG2303@1|root,COG3485@1|root,COG2303@2|Bacteria,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	choD_1	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	CarboxypepD_reg,FAD_oxidored,GMC_oxred_C,GMC_oxred_N,PhoD
GDHHQS1_k127_9846899_2	247490.KSU1_C0377	4.087e-24	115.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Beta_helix,DUF1565,Laminin_G_3,Metallophos
GDHHQS1_k127_9846899_1	1125863.JAFN01000001_gene1170	1.188e-30	126.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42VSX@68525|delta/epsilon subdivisions,2WS1I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
GDHHQS1_k127_9846899_3	323259.Mhun_1034	3.473e-11	63.0	COG1465@1|root,arCOG04353@2157|Archaea,2XSXD@28890|Euryarchaeota,2N9AV@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
GDHHQS1_k127_9847125_3	247490.KSU1_B0511	0.0002677	44.0	COG1253@1|root,COG1253@2|Bacteria,2IYEG@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS1_k127_9847125_0	349741.Amuc_0429	1.935e-59	211.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS1_k127_9847125_1	1121017.AUFG01000011_gene1754	2.781e-58	214.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4FEHC@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS1_k127_9847125_2	426368.MmarC7_1556	6.1e-12	68.0	arCOG06621@1|root,arCOG06621@2157|Archaea,2Y3GZ@28890|Euryarchaeota,23RKE@183939|Methanococci	183939|Methanococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_9856273_2	756272.Plabr_2714	2.933e-77	267.0	COG2755@1|root,COG2755@2|Bacteria,2J37I@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS1_k127_9856273_0	1396141.BATP01000039_gene1428	9.269e-235	739.0	COG3664@1|root,COG3664@2|Bacteria,46U9J@74201|Verrucomicrobia,2IV6J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
GDHHQS1_k127_9856273_4	391596.PBAL39_11297	2.189e-17	83.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS1_k127_9856273_3	1047013.AQSP01000122_gene2257	3.515e-24	107.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	prfA3	-	-	-	-	-	-	-	-	-	-	-	RF-1
GDHHQS1_k127_9856273_1	886293.Sinac_6933	8.176e-94	319.0	COG0657@1|root,COG0657@2|Bacteria,2IZ4H@203682|Planctomycetes	203682|Planctomycetes	G	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS1_k127_9872342_1	234267.Acid_2265	5.193e-111	363.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS1_k127_9872342_0	234267.Acid_2266	1.649e-174	583.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
GDHHQS1_k127_9874651_4	344747.PM8797T_06335	1.964e-30	134.0	COG2730@1|root,COG2730@2|Bacteria,2IWW8@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS1_k127_9874651_3	247490.KSU1_C0729	3.163e-52	198.0	COG0616@1|root,COG0616@2|Bacteria,2IYKF@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS1_k127_9874651_1	926550.CLDAP_32200	6.475e-81	285.0	COG0246@1|root,COG0246@2|Bacteria	2|Bacteria	G	mannitol metabolic process	-	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
GDHHQS1_k127_9874651_0	1123276.KB893313_gene3834	1.938e-158	506.0	COG2017@1|root,COG2017@2|Bacteria,4NHQH@976|Bacteroidetes,47JMF@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
GDHHQS1_k127_9874651_5	575540.Isop_0083	5.254e-11	75.0	COG0524@1|root,COG0524@2|Bacteria,2IX8I@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS1_k127_9874651_2	1123248.KB893385_gene4912	1.451e-68	234.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_988468_0	1142394.PSMK_29780	6.58e-65	232.0	COG0515@1|root,COG0515@2|Bacteria,2IZHV@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS1_k127_988468_2	314230.DSM3645_15505	4.129e-47	180.0	COG0639@1|root,COG0639@2|Bacteria,2IZ5T@203682|Planctomycetes	203682|Planctomycetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS1_k127_988468_3	234267.Acid_1399	4.091e-38	159.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
GDHHQS1_k127_988468_1	234267.Acid_5490	7.127e-60	230.0	COG3420@1|root,COG3420@2|Bacteria,3Y67Z@57723|Acidobacteria	57723|Acidobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS1_k127_9980802_1	1396141.BATP01000027_gene1160	1.44e-33	149.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
GDHHQS1_k127_9980802_0	118168.MC7420_2811	1.244e-46	190.0	COG2133@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3EW@1117|Cyanobacteria,1HBBU@1150|Oscillatoriales	1117|Cyanobacteria	Q	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8,HemolysinCabind,Laminin_G_3,PKD
GDHHQS1_k127_999570_2	745411.B3C1_01535	4.352e-31	126.0	2E9E9@1|root,333MS@2|Bacteria,1NBUG@1224|Proteobacteria,1SG75@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Family of unknown function (DUF5362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
GDHHQS1_k127_999570_3	768671.ThimaDRAFT_2989	8.144e-22	98.0	2ED63@1|root,3372T@2|Bacteria,1NEJK@1224|Proteobacteria,1SD1X@1236|Gammaproteobacteria,1WZG9@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS1_k127_999570_4	1218173.BALCAV_0220420	0.0001038	51.0	COG3266@1|root,COG3266@2|Bacteria,1VDA3@1239|Firmicutes,4ITGR@91061|Bacilli,1ZDHT@1386|Bacillus	91061|Bacilli	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,TPR_19
GDHHQS1_k127_999570_1	886293.Sinac_6469	5.561e-161	516.0	COG0436@1|root,COG0436@2|Bacteria,2IY66@203682|Planctomycetes	203682|Planctomycetes	E	aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS1_k127_999570_0	575540.Isop_2659	1.244e-201	638.0	COG0516@1|root,COG0516@2|Bacteria,2IX43@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
## 1941 queries scanned
## Total time (seconds): 181.16044521331787
## Rate: 10.71 q/s