## Mon Feb 16 21:49:20 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/GDHHQS2_bin.54.fa -m mmseqs --output GDHHQS2_bin.54 --output_dir /data/result/bins/wyx/eggqs50+/GDHHQS2_bin.54 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS2_k127_1003028_1	1340493.JNIF01000004_gene935	4.585e-107	352.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1003028_6	338969.Rfer_1769	9.885e-27	114.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,2VQRB@28216|Betaproteobacteria,4AIFM@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1003028_3	880070.Cycma_1229	1.733e-102	350.0	COG3119@1|root,COG3119@2|Bacteria,4NP9D@976|Bacteroidetes	976|Bacteroidetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_1003028_7	1192034.CAP_5852	9.157e-26	119.0	COG1716@1|root,COG1716@2|Bacteria,1R7XU@1224|Proteobacteria	1224|Proteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123,Yop-YscD_cpl
GDHHQS2_k127_1003028_5	1408224.SAMCCGM7_c4250	2.325e-29	131.0	2CM80@1|root,32SDY@2|Bacteria,1N9TE@1224|Proteobacteria,2UX2G@28211|Alphaproteobacteria,4BDZ6@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1003028_4	247633.GP2143_13281	3.975e-87	303.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1SEI7@1236|Gammaproteobacteria,1J802@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1003028_0	234267.Acid_6511	9.065e-195	628.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria	57723|Acidobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_1003028_2	1123242.JH636434_gene5158	4.792e-106	363.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
GDHHQS2_k127_100695_0	234267.Acid_7204	9.402e-293	906.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS2_k127_100695_1	344747.PM8797T_13183	1.446e-224	725.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_100695_2	756272.Plabr_4285	9.451e-216	678.0	COG3119@1|root,COG3119@2|Bacteria,2IXXZ@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_100695_4	1340493.JNIF01000003_gene4208	4.622e-58	208.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_100695_5	234267.Acid_5282	6.986e-28	128.0	COG2133@1|root,COG2373@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Laminin_G_3,PA14,VPEP
GDHHQS2_k127_100695_6	234267.Acid_2335	1.709e-11	69.0	COG1092@1|root,COG1092@2|Bacteria,3Y2PV@57723|Acidobacteria	57723|Acidobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS2_k127_100695_3	234267.Acid_3066	3.346e-93	322.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1016418_0	1340493.JNIF01000004_gene88	9.871e-153	505.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1017673_2	485917.Phep_1358	2.731e-15	86.0	COG3391@1|root,COG4632@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,4NNEF@976|Bacteroidetes,1ISMB@117747|Sphingobacteriia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,NHL,TIG
GDHHQS2_k127_1017673_1	1195246.AGRI_01840	7.448e-22	98.0	COG2002@1|root,COG2002@2|Bacteria,1NBUR@1224|Proteobacteria,1SSDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS2_k127_1017673_0	748658.KB907319_gene714	1.518e-23	102.0	COG1848@1|root,COG1848@2|Bacteria,1RFD9@1224|Proteobacteria,1S6PP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_1019224_3	886293.Sinac_1155	1.346e-80	278.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
GDHHQS2_k127_1019224_1	886293.Sinac_1154	1.103e-204	646.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_1019224_0	1340493.JNIF01000004_gene920	2.212e-300	948.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_1019224_2	234267.Acid_7728	3.392e-109	363.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1023655_2	870187.Thini_4118	1.42e-29	130.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria,1SHNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_1023655_0	1267535.KB906767_gene3495	4.646e-237	755.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
GDHHQS2_k127_1023655_1	1340493.JNIF01000003_gene2485	3.584e-103	344.0	COG1596@1|root,COG1596@2|Bacteria,3Y7QA@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS2_k127_1026054_3	234267.Acid_0449	1.619e-85	289.0	COG1801@1|root,COG1801@2|Bacteria,3Y2F1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS2_k127_1026054_1	1206732.BAGD01000107_gene5033	1.505e-161	522.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria,4FZTK@85025|Nocardiaceae	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,PAP2
GDHHQS2_k127_1026054_0	234267.Acid_1347	0.0	1024.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria	57723|Acidobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS2_k127_1026054_2	1267535.KB906767_gene4321	1.68e-141	456.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria,2JI1R@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
GDHHQS2_k127_1026054_4	1318628.MARLIPOL_16394	5.1e-25	108.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_102921_1	1123242.JH636437_gene6091	5.082e-54	193.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
GDHHQS2_k127_102921_0	616991.JPOO01000003_gene1588	1.959e-101	339.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,1IAQY@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_102921_2	357808.RoseRS_0687	0.0001085	55.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
GDHHQS2_k127_1039113_13	234267.Acid_5098	2.562e-10	60.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria	57723|Acidobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS2_k127_1039113_3	1340493.JNIF01000003_gene3227	2.291e-108	353.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria	57723|Acidobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS2_k127_1039113_6	234267.Acid_5097	1.411e-66	233.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GDHHQS2_k127_1039113_2	1340493.JNIF01000003_gene3229	6.408e-127	411.0	COG0024@1|root,COG0024@2|Bacteria,3Y2HJ@57723|Acidobacteria	57723|Acidobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS2_k127_1039113_12	234267.Acid_5095	1.107e-10	68.0	COG0361@1|root,COG0361@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS2_k127_1039113_11	1267534.KB906757_gene797	1.175e-15	76.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria,2JK4W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS2_k127_1039113_9	1267535.KB906767_gene2681	1.508e-57	203.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria,2JJAF@204432|Acidobacteriia	204432|Acidobacteriia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS2_k127_1039113_7	1267535.KB906767_gene2680	8.595e-62	222.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS2_k127_1039113_4	234267.Acid_5091	6.331e-90	302.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS2_k127_1039113_1	1267535.KB906767_gene2678	3.658e-173	549.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS2_k127_1039113_8	234267.Acid_5089	3.622e-60	211.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS2_k127_1039113_5	234267.Acid_4025	2.942e-71	252.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	CheW,NMT1,NMT1_2,OmpA,Phosphonate-bd,Response_reg,Sigma70_r2
GDHHQS2_k127_1039113_0	234267.Acid_3341	2.573e-251	808.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HY@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1039113_10	1185876.BN8_04374	1.348e-23	110.0	COG4247@1|root,COG4247@2|Bacteria,4NH2W@976|Bacteroidetes,47N7A@768503|Cytophagia	976|Bacteroidetes	I	Phytase	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
GDHHQS2_k127_1040266_4	278963.ATWD01000003_gene114	7.201e-19	91.0	COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,3Y3MB@57723|Acidobacteria,2JI3M@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Trans_reg_C
GDHHQS2_k127_1040266_1	448385.sce3381	3.439e-46	179.0	COG3386@1|root,COG3386@2|Bacteria,1QY38@1224|Proteobacteria,43CUW@68525|delta/epsilon subdivisions,2X82P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
GDHHQS2_k127_1040266_2	234267.Acid_0353	8.758e-29	118.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_1040266_3	596154.Alide2_4309	3.564e-21	94.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,2VPAP@28216|Betaproteobacteria,4AFM7@80864|Comamonadaceae	28216|Betaproteobacteria	L	Insertion element 4 transposase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
GDHHQS2_k127_1040266_0	641524.ADICYQ_5476	2.474e-130	426.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,47YCZ@768503|Cytophagia	976|Bacteroidetes	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_1042421_2	575540.Isop_2259	2.894e-32	130.0	COG2010@1|root,COG2010@2|Bacteria,2J55S@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1042421_1	1121438.JNJA01000002_gene3375	2.371e-89	303.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2M812@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	ada	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
GDHHQS2_k127_1042421_3	1548153.LR59_10500	1.765e-07	61.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2YMEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
GDHHQS2_k127_1042421_0	1340493.JNIF01000003_gene2320	1.203e-123	413.0	COG1629@1|root,COG4771@2|Bacteria	1340493.JNIF01000003_gene2320|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1047986_4	234267.Acid_6753	9.589e-50	196.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,3Y4DW@57723|Acidobacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1,3.4.21.53	ko:K01338,ko:K04757,ko:K06379,ko:K08282,ko:K17752	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko03021	-	-	-	HATPase_c_2,HTH_8,Response_reg
GDHHQS2_k127_1047986_0	886293.Sinac_7544	5.064e-180	603.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2J4YH@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
GDHHQS2_k127_1047986_3	234267.Acid_3857	2.185e-58	204.0	COG0139@1|root,COG0139@2|Bacteria,3Y4SN@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	-	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
GDHHQS2_k127_1047986_1	234267.Acid_3856	4.936e-152	483.0	COG0040@1|root,COG0040@2|Bacteria,3Y31Q@57723|Acidobacteria	57723|Acidobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
GDHHQS2_k127_1047986_2	234267.Acid_3855	1.599e-111	368.0	COG0141@1|root,COG0141@2|Bacteria,3Y2N7@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
GDHHQS2_k127_1048059_1	1267535.KB906767_gene1827	2.224e-52	192.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1048059_0	1122214.AQWH01000016_gene1588	4.989e-76	273.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,2TV04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_1057486_1	1340493.JNIF01000004_gene454	1.518e-92	312.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	M1-534	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,SLH
GDHHQS2_k127_1057486_0	234267.Acid_7745	1.463e-108	359.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_1057486_2	234267.Acid_7746	4.024e-13	69.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_1069785_1	278963.ATWD01000001_gene2919	6.567e-58	218.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1069785_2	204669.Acid345_3054	2.53e-52	191.0	COG0572@1|root,COG0572@2|Bacteria,3Y4EI@57723|Acidobacteria,2JJ43@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS2_k127_1069785_0	1267535.KB906767_gene4432	2.375e-149	511.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1069785_4	204669.Acid345_1582	1.73e-06	57.0	2EEIP@1|root,338CM@2|Bacteria,3Y5Q1@57723|Acidobacteria,2JK0Z@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1069785_3	1219035.NT2_01_05570	2.578e-27	115.0	28K8V@1|root,2Z9WK@2|Bacteria,1R70Q@1224|Proteobacteria,2UQX5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1073275_1	1120953.AUBH01000008_gene198	1.691e-07	59.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,1RP38@1236|Gammaproteobacteria,465NW@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_1073275_0	234267.Acid_3343	4.176e-218	688.0	COG4948@1|root,COG4948@2|Bacteria,3Y61U@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1076664_5	1340493.JNIF01000003_gene4575	8.443e-192	633.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1076664_7	1340493.JNIF01000003_gene4574	9.752e-160	520.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1076664_1	1267535.KB906767_gene3524	9.835e-306	971.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1076664_11	1089547.KB913013_gene761	4.173e-19	92.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_1076664_0	234267.Acid_6432	0.0	1044.0	COG0497@1|root,COG3266@1|root,COG0497@2|Bacteria,COG3266@2|Bacteria,3Y6KC@57723|Acidobacteria	57723|Acidobacteria	L	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1076664_4	234267.Acid_6433	1.188e-209	670.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
GDHHQS2_k127_1076664_8	234267.Acid_6434	1.313e-128	422.0	COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_1076664_6	234267.Acid_6435	1.415e-162	517.0	COG0714@1|root,COG0714@2|Bacteria,3Y3BH@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_1076664_3	1267535.KB906767_gene907	2.977e-244	776.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_16,TPR_19,TPR_8
GDHHQS2_k127_1076664_9	1267535.KB906767_gene906	1.832e-80	289.0	COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
GDHHQS2_k127_1076664_2	234267.Acid_6438	1.76e-269	851.0	COG1572@1|root,COG2304@1|root,COG5426@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6YC@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
GDHHQS2_k127_1076664_10	1340493.JNIF01000003_gene4787	1.484e-36	138.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_1077821_1	234267.Acid_1905	2.366e-116	401.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
GDHHQS2_k127_1077821_0	234267.Acid_1906	2.42e-189	636.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.6.4.12	ko:K01144,ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF3799,PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS2_k127_1077821_2	234267.Acid_4361	1.352e-29	118.0	COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria	57723|Acidobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
GDHHQS2_k127_1092308_4	357808.RoseRS_0181	5.309e-18	89.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_1092308_0	497964.CfE428DRAFT_4513	6.864e-180	578.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	MA20_44000	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1092308_1	1267535.KB906767_gene1477	2.036e-132	429.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_1092308_2	1408473.JHXO01000009_gene3488	3.194e-104	356.0	COG0667@1|root,COG0667@2|Bacteria,4P42C@976|Bacteroidetes	976|Bacteroidetes	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1092308_5	278963.ATWD01000001_gene1445	2.832e-09	63.0	COG1629@1|root,COG1629@2|Bacteria,3Y2N1@57723|Acidobacteria,2JIIP@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1092315_5	234267.Acid_5783	3.122e-42	156.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_1092315_4	1288963.ADIS_4346	2.425e-94	322.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,47NJD@768503|Cytophagia	976|Bacteroidetes	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_1092315_3	1267535.KB906767_gene220	5.045e-173	553.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria,2JKWG@204432|Acidobacteriia	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_1092315_9	234267.Acid_2721	2.022e-13	72.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_1092315_1	1267535.KB906767_gene223	1.512e-229	750.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1092315_8	639030.JHVA01000001_gene880	7.034e-16	84.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria,2JI2M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1092315_6	1340493.JNIF01000003_gene2321	4.594e-26	117.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1092315_7	1122621.ATZA01000008_gene863	1.436e-20	92.0	COG1502@1|root,COG1502@2|Bacteria,4NMXS@976|Bacteroidetes,1ISBY@117747|Sphingobacteriia	976|Bacteroidetes	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
GDHHQS2_k127_1092315_11	1122605.KB893626_gene2580	0.000392	44.0	COG1502@1|root,COG1502@2|Bacteria,4PNEI@976|Bacteroidetes	976|Bacteroidetes	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
GDHHQS2_k127_1092315_0	1340493.JNIF01000003_gene3458	5.098e-291	917.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1092315_2	1340493.JNIF01000003_gene3459	1.27e-178	571.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1092360_0	1379698.RBG1_1C00001G0607	2.407e-87	314.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS2_k127_109749_3	228405.HNE_2524	0.0002615	48.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,2TX0D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_109749_1	1183438.GKIL_3021	1.29e-89	338.0	COG3291@1|root,COG3291@2|Bacteria,1GR9W@1117|Cyanobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP,TIG
GDHHQS2_k127_109749_0	1499967.BAYZ01000016_gene6521	5.462e-162	571.0	COG3209@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,WXG100
GDHHQS2_k127_109749_2	448385.sce2405	2.999e-08	59.0	COG0682@1|root,COG0682@2|Bacteria,1Q2R4@1224|Proteobacteria,438CQ@68525|delta/epsilon subdivisions,2WP0G@28221|Deltaproteobacteria,2YWK4@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS2_k127_1098979_0	1121920.AUAU01000007_gene416	2.959e-177	573.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
GDHHQS2_k127_1098979_1	234267.Acid_7823	6.232e-125	409.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1104948_0	1122132.AQYH01000010_gene4213	6.22e-47	172.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,4BCUD@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Iron-containing alcohol dehydrogenase	gbd	-	1.1.1.61	ko:K00043	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_1104948_3	1267533.KB906737_gene1630	7.838e-05	54.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS2_k127_1104948_1	797209.ZOD2009_15776	2.917e-18	86.0	COG0451@1|root,arCOG03019@2157|Archaea,2XVZH@28890|Euryarchaeota,23U95@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_1107853_0	234267.Acid_0974	1.45e-170	541.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1107853_2	234267.Acid_5753	4.339e-25	109.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1107853_1	864069.MicloDRAFT_00063550	1.94e-57	211.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	yjaU	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
GDHHQS2_k127_1107853_3	1312954.KI914890_gene2171	6.025e-25	104.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,1W9UJ@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_1108514_0	1267535.KB906767_gene3106	7.628e-283	897.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1111117_7	1469557.JSWF01000032_gene3163	2.621e-08	66.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
GDHHQS2_k127_1111117_4	1385517.N800_00455	4.123e-27	127.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GDHHQS2_k127_1111117_0	234267.Acid_7606	5.464e-227	731.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1111117_3	1267535.KB906767_gene3496	5.592e-47	177.0	COG1943@1|root,COG1943@2|Bacteria,3Y84T@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS2_k127_1111117_2	234267.Acid_6465	1.368e-96	352.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1111117_5	1122605.KB893625_gene1983	6.366e-25	108.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,1J119@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_1111117_6	105425.BBPL01000013_gene1761	2.754e-18	94.0	COG1802@1|root,COG1802@2|Bacteria,2H1S8@201174|Actinobacteria,2NJQS@228398|Streptacidiphilus	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_1111117_1	234267.Acid_2685	1.488e-109	380.0	COG1629@1|root,COG4771@2|Bacteria,3Y9A9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1113090_3	395963.Bind_2543	2.863e-100	333.0	COG2706@1|root,COG2706@2|Bacteria,1R9QR@1224|Proteobacteria,2U4RJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_1113090_5	377629.TERTU_3523	4.286e-05	49.0	COG2128@1|root,COG2128@2|Bacteria,1RASD@1224|Proteobacteria,1S391@1236|Gammaproteobacteria,2PNWX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_1113090_4	1523503.JPMY01000042_gene2952	1.989e-06	54.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_1113090_1	631454.N177_1889	6.775e-122	403.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria,1JPNF@119043|Rhodobiaceae	28211|Alphaproteobacteria	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_1113090_0	1380394.JADL01000001_gene2254	4.438e-126	412.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2JPM8@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon-nitrogen hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_1113090_2	1122604.JONR01000039_gene3778	1.494e-101	336.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria,1XC99@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_30
GDHHQS2_k127_1114914_0	234267.Acid_3565	3.811e-174	562.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	ASH,CarboxypepD_reg,DUF11,FlgD_ig,HYR,Laminin_G_3,Plug,TonB_dep_Rec
GDHHQS2_k127_1114914_1	1340493.JNIF01000004_gene88	7.523e-121	404.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1114914_3	234267.Acid_0095	7.026e-34	136.0	2EMD6@1|root,33F24@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1114914_4	926566.Terro_2941	1.182e-19	94.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria,2JKDK@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1114914_2	401053.AciPR4_2767	3.321e-116	395.0	COG1629@1|root,COG1629@2|Bacteria,3Y2K8@57723|Acidobacteria,2JKEC@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1116810_2	1340493.JNIF01000003_gene4293	3.801e-170	574.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1116810_3	1198114.AciX9_0511	4.018e-164	527.0	COG1301@1|root,COG1301@2|Bacteria,3Y3V3@57723|Acidobacteria,2JKMW@204432|Acidobacteriia	204432|Acidobacteriia	C	Sodium:dicarboxylate symporter family	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
GDHHQS2_k127_1116810_8	1173264.KI913949_gene1836	3.106e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
GDHHQS2_k127_1116810_7	1173023.KE650771_gene2827	6.914e-14	84.0	COG0457@1|root,COG0457@2|Bacteria,1G4DP@1117|Cyanobacteria,1JI6C@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_8
GDHHQS2_k127_1116810_5	1267535.KB906767_gene1051	6.737e-105	348.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	M1-769	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_1116810_0	234267.Acid_5088	3.755e-210	670.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_1116810_4	1121930.AQXG01000003_gene2586	4.237e-118	392.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,1IPB9@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
GDHHQS2_k127_1116810_1	234267.Acid_3963	6.21e-194	615.0	COG1629@1|root,COG4771@2|Bacteria,3Y2HF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1118287_1	1267535.KB906767_gene3728	1.315e-109	373.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_1118287_2	595460.RRSWK_00702	1.8e-102	349.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_1118287_0	234267.Acid_3725	7.025e-123	406.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_1121011_0	240016.ABIZ01000001_gene4800	2.812e-112	376.0	COG1520@1|root,COG1520@2|Bacteria,46TM3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_1121011_3	56110.Oscil6304_1161	1.285e-42	163.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria,1H9TN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1121011_1	710686.Mycsm_00054	2.306e-92	312.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
GDHHQS2_k127_1121011_4	864702.OsccyDRAFT_1310	9.794e-21	105.0	2BVTZ@1|root,32U84@2|Bacteria,1G7UE@1117|Cyanobacteria,1HCEE@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1121011_2	391625.PPSIR1_07173	9.533e-52	194.0	COG1881@1|root,COG1881@2|Bacteria	2|Bacteria	S	positive regulation of acetylcholine metabolic process	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	CBM_6,GSDH,PBP,Polyketide_cyc2,YHYH,fn3
GDHHQS2_k127_1130727_4	1231190.NA8A_00420	1.119e-36	149.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,43J36@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
GDHHQS2_k127_1130727_0	1267535.KB906767_gene4432	6.733e-204	681.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1130727_1	240016.ABIZ01000001_gene2352	1.762e-201	653.0	COG2072@1|root,COG2072@2|Bacteria,46U3S@74201|Verrucomicrobia	74201|Verrucomicrobia	P	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_1130727_2	1267535.KB906767_gene3768	1.299e-169	576.0	COG1629@1|root,COG1629@2|Bacteria,3Y2K8@57723|Acidobacteria,2JKEC@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1130727_5	344747.PM8797T_12743	7.202e-19	92.0	2EK8J@1|root,33DYX@2|Bacteria,2J1AU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1130727_3	926566.Terro_0943	1.429e-159	546.0	COG1629@1|root,COG4771@2|Bacteria	926566.Terro_0943|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1130727_6	234267.Acid_7914	5.421e-14	77.0	COG0457@1|root,COG0457@2|Bacteria,3Y7TN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1140964_0	1379698.RBG1_1C00001G1367	8.285e-64	232.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1140964_1	204669.Acid345_2395	2.206e-47	173.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_1141653_2	234267.Acid_2396	1.949e-54	198.0	COG0652@1|root,COG0652@2|Bacteria,3Y7SZ@57723|Acidobacteria	57723|Acidobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS2_k127_1141653_8	1961.JOAK01000001_gene3470	2.956e-13	81.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
GDHHQS2_k127_1141653_5	67356.KL575596_gene6699	1.768e-23	116.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
GDHHQS2_k127_1141653_7	1132855.KB913035_gene1740	3.967e-14	83.0	COG1403@1|root,COG1403@2|Bacteria,1N3X9@1224|Proteobacteria,2VY11@28216|Betaproteobacteria	28216|Betaproteobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GDHHQS2_k127_1141653_4	340177.Cag_0257	1.58e-23	113.0	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
GDHHQS2_k127_1141653_1	234267.Acid_5363	4.031e-136	442.0	COG0232@1|root,COG0232@2|Bacteria,3Y2S2@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
GDHHQS2_k127_1141653_3	234267.Acid_5362	1.125e-31	134.0	COG2976@1|root,COG2976@2|Bacteria,3Y9AW@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
GDHHQS2_k127_1141653_9	1042163.BRLA_c035610	0.0008481	45.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,4HQKX@91061|Bacilli,27724@186822|Paenibacillaceae	91061|Bacilli	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
GDHHQS2_k127_1141653_6	118168.MC7420_7727	6.749e-16	81.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales	1117|Cyanobacteria	S	KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
GDHHQS2_k127_1141653_0	234267.Acid_1003	6.002e-158	507.0	COG2407@1|root,COG2407@2|Bacteria,3Y63P@57723|Acidobacteria	57723|Acidobacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1146772_0	471854.Dfer_5257	5.561e-152	495.0	COG0001@1|root,COG0001@2|Bacteria,4NK1U@976|Bacteroidetes,47UFQ@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_1146772_1	1340493.JNIF01000003_gene4208	5.159e-40	158.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_1148758_1	324602.Caur_1677	2.103e-54	199.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,2G6ND@200795|Chloroflexi,376W1@32061|Chloroflexia	32061|Chloroflexia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HD,Response_reg
GDHHQS2_k127_1148758_2	247490.KSU1_D0362	4.285e-05	55.0	COG1730@1|root,COG1730@2|Bacteria	2|Bacteria	O	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1148758_0	234267.Acid_2685	2.183e-176	571.0	COG1629@1|root,COG4771@2|Bacteria,3Y9A9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1149502_13	234267.Acid_6674	7.609e-11	63.0	COG0535@1|root,COG0535@2|Bacteria,3Y5QY@57723|Acidobacteria	57723|Acidobacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
GDHHQS2_k127_1149502_11	1121946.AUAX01000023_gene4247	2.019e-11	77.0	COG3397@1|root,COG3397@2|Bacteria,2GM54@201174|Actinobacteria,4D8MR@85008|Micromonosporales	201174|Actinobacteria	S	Chitin-binding protein	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	LPMO_10
GDHHQS2_k127_1149502_6	1038858.AXBA01000016_gene1903	3.055e-111	383.0	COG3979@1|root,COG3979@2|Bacteria,1R5T0@1224|Proteobacteria,2VEZG@28211|Alphaproteobacteria,3EYEA@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Chitin-binding domain type 3	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,fn3
GDHHQS2_k127_1149502_7	1207063.P24_09791	4.101e-43	167.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,2JSQY@204441|Rhodospirillales	204441|Rhodospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GDHHQS2_k127_1149502_5	1340493.JNIF01000004_gene721	1.028e-147	476.0	COG0416@1|root,COG0416@2|Bacteria,3Y3MM@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS2_k127_1149502_9	639030.JHVA01000001_gene1787	4.002e-24	102.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JJZ9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS2_k127_1149502_1	497964.CfE428DRAFT_2120	1.42e-300	937.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_1149502_0	234267.Acid_4184	0.0	1722.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3Y37Y@57723|Acidobacteria	57723|Acidobacteria	E	Vitamin B12 dependent methionine synthase activation	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS2_k127_1149502_4	234267.Acid_5749	3.936e-160	535.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_1149502_3	543728.Vapar_0124	3.446e-190	609.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VIK2@28216|Betaproteobacteria,4ACVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_1149502_10	483219.LILAB_29000	3.317e-18	97.0	COG1716@1|root,COG1716@2|Bacteria,1N47K@1224|Proteobacteria,434WB@68525|delta/epsilon subdivisions,2WZ7A@28221|Deltaproteobacteria,2Z1HC@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
GDHHQS2_k127_1149502_12	1123242.JH636435_gene1503	4.71e-11	74.0	COG1716@1|root,COG1716@2|Bacteria,2J13J@203682|Planctomycetes	203682|Planctomycetes	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
GDHHQS2_k127_1149502_2	234267.Acid_3485	3.236e-248	782.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1149502_8	234267.Acid_3484	1.586e-41	156.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS2_k127_1152440_0	1340493.JNIF01000004_gene88	1.563e-268	865.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1152440_1	344747.PM8797T_05840	1.169e-173	561.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_1152440_9	234267.Acid_1010	1.338e-17	83.0	COG1826@1|root,COG1826@2|Bacteria,3Y5V7@57723|Acidobacteria	57723|Acidobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS2_k127_1152440_6	1340493.JNIF01000004_gene518	8.566e-40	149.0	COG0776@1|root,COG0776@2|Bacteria,3Y50P@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS2_k127_1152440_7	638303.Thal_1055	1.148e-39	157.0	COG0468@1|root,COG0468@2|Bacteria,2G3UK@200783|Aquificae	200783|Aquificae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_1152440_2	234267.Acid_7375	4.539e-172	544.0	COG0057@1|root,COG0057@2|Bacteria,3Y2QC@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS2_k127_1152440_5	118161.KB235919_gene6155	2.282e-53	206.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,3VJHN@52604|Pleurocapsales	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_1152440_11	208444.JNYY01000012_gene7861	3.302e-06	53.0	COG0236@1|root,COG0236@2|Bacteria,2GRK8@201174|Actinobacteria,4E6XH@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS2_k127_1152440_12	644968.DFW101_1580	0.0001223	53.0	COG1560@1|root,COG1560@2|Bacteria,1PAMJ@1224|Proteobacteria	1224|Proteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS2_k127_1152440_4	456442.Mboo_2001	6.086e-88	307.0	COG2516@1|root,arCOG00662@2157|Archaea	2157|Archaea	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_1152440_8	502025.Hoch_4739	1.147e-27	122.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS2_k127_1152440_3	452637.Oter_4538	3.016e-115	383.0	COG3828@1|root,COG3828@2|Bacteria,46TVD@74201|Verrucomicrobia,3K8Z8@414999|Opitutae	414999|Opitutae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS2_k127_1156137_2	1340493.JNIF01000003_gene1468	4.573e-95	320.0	COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria	57723|Acidobacteria	S	nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
GDHHQS2_k127_1156137_3	234267.Acid_7418	3.975e-34	135.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS2_k127_1156137_1	234267.Acid_3883	1.75e-128	422.0	COG0446@1|root,COG0446@2|Bacteria,3Y7RT@57723|Acidobacteria	57723|Acidobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_1156137_0	234267.Acid_3953	2.173e-239	746.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1156137_4	344747.PM8797T_29753	4.05e-10	62.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1161062_0	234267.Acid_2567	3.255e-152	500.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1165703_5	234267.Acid_1306	7.455e-162	544.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1165703_4	1337936.IJ00_11110	2.011e-164	535.0	COG2931@1|root,COG2931@2|Bacteria,1GR9Z@1117|Cyanobacteria,1HMN8@1161|Nostocales	1117|Cyanobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
GDHHQS2_k127_1165703_0	234267.Acid_6586	6.697e-294	931.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3ZP@57723|Acidobacteria	57723|Acidobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_1165703_8	246197.MXAN_2314	1.23e-127	417.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,43C6E@68525|delta/epsilon subdivisions,2WTIV@28221|Deltaproteobacteria,2YZ25@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_1165703_13	1352941.M877_38185	2.096e-07	64.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Cys_Met_Meta_PP
GDHHQS2_k127_1165703_3	344747.PM8797T_06847	2.268e-170	554.0	COG0657@1|root,COG3458@1|root,COG0657@2|Bacteria,COG3458@2|Bacteria,2J1TC@203682|Planctomycetes	203682|Planctomycetes	Q	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1165703_9	886293.Sinac_5627	2.841e-96	330.0	COG2421@1|root,COG2421@2|Bacteria,2J06T@203682|Planctomycetes	203682|Planctomycetes	C	acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
GDHHQS2_k127_1165703_10	1267535.KB906767_gene1059	8.054e-90	306.0	COG0644@1|root,COG0644@2|Bacteria,3Y5HW@57723|Acidobacteria,2JK2B@204432|Acidobacteriia	204432|Acidobacteriia	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1165703_1	234267.Acid_5378	3.989e-203	637.0	COG0436@1|root,COG0436@2|Bacteria,3Y6EJ@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_1165703_12	234267.Acid_3427	1.004e-77	269.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_17_28,CBM_2,Cellulase,SLH
GDHHQS2_k127_1165703_6	525904.Tter_2007	1.56e-148	492.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1165703_11	314230.DSM3645_07805	6.126e-85	294.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5,Peptidase_S9
GDHHQS2_k127_1165703_2	1340493.JNIF01000003_gene4723	2.566e-181	582.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1,3.1.6.8	ko:K01130,ko:K01134	ko00140,ko00600,ko04142,map00140,map00600,map04142	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1165703_7	1340493.JNIF01000004_gene88	2.3e-130	434.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1178911_4	373994.Riv7116_4018	2.002e-45	168.0	COG2382@1|root,COG2382@2|Bacteria,1G24A@1117|Cyanobacteria	1117|Cyanobacteria	P	esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS2_k127_1178911_1	1392838.AWNM01000097_gene116	7.756e-104	344.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VMWW@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_1178911_2	1380391.JIAS01000017_gene738	2.941e-86	293.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,2JUEV@204441|Rhodospirillales	204441|Rhodospirillales	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1178911_0	1380391.JIAS01000017_gene737	1.476e-169	545.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TSAB@28211|Alphaproteobacteria,2JRJP@204441|Rhodospirillales	204441|Rhodospirillales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1178911_3	1382359.JIAL01000001_gene1409	8.029e-61	219.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKYK@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1181172_1	1382359.JIAL01000001_gene122	4.811e-190	603.0	COG3387@1|root,COG3387@2|Bacteria,3Y3QW@57723|Acidobacteria,2JIEZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF5127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127
GDHHQS2_k127_1181172_0	234267.Acid_1528	1.495e-233	733.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria	2|Bacteria	P	PFAM Sulfatase	atsA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_1181172_2	1144275.COCOR_05906	1.448e-142	481.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1184501_11	1230341.MJ3_13589	8.505e-05	48.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_1184501_10	1267533.KB906742_gene786	3.14e-05	48.0	COG0823@1|root,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_1184501_9	1123508.JH636440_gene2753	5.715e-19	91.0	COG1598@1|root,COG1598@2|Bacteria,2J4N9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1184501_7	1173026.Glo7428_3849	4.511e-21	94.0	COG1724@1|root,COG1724@2|Bacteria,1G9Z7@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_1184501_3	1340493.JNIF01000004_gene1085	2.056e-97	338.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K06370	-	-	-	-	ko00000	-	-	-	CW_binding_1,Flg_new,GGDEF,Gram_pos_anchor,LysM,WD40
GDHHQS2_k127_1184501_0	1340493.JNIF01000004_gene1086	1.687e-301	952.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2
GDHHQS2_k127_1184501_1	1340493.JNIF01000004_gene1087	1.254e-196	621.0	COG4102@1|root,COG4102@2|Bacteria	1340493.JNIF01000004_gene1087|-	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1184501_12	1121926.AXWO01000026_gene2722	0.0001958	47.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_1184501_2	880070.Cycma_0165	4.299e-124	409.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_1184501_5	1267535.KB906767_gene4885	2.461e-40	153.0	COG1082@1|root,COG1082@2|Bacteria,3Y7EJ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1184501_6	1267535.KB906767_gene4885	1.221e-30	135.0	COG1082@1|root,COG1082@2|Bacteria,3Y7EJ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1184501_4	1123242.JH636434_gene3154	3.216e-74	264.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_1184501_8	1267535.KB906767_gene836	1.182e-19	94.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria,2JM3M@204432|Acidobacteriia	204432|Acidobacteriia	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1185341_3	234267.Acid_4704	5.828e-108	364.0	COG2055@1|root,COG2055@2|Bacteria,3Y3IZ@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
GDHHQS2_k127_1185341_2	1340493.JNIF01000003_gene4181	3.394e-124	405.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_1185341_4	1346791.M529_18940	4.259e-41	162.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_1185341_7	35754.JNYJ01000007_gene2760	1.598e-07	59.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DD6M@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
GDHHQS2_k127_1185341_1	1340493.JNIF01000003_gene2784	1.312e-143	467.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_1185341_0	234267.Acid_7720	1.198e-243	760.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS2_k127_1185341_5	1229780.BN381_750002	5.593e-18	88.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1185341_6	204669.Acid345_2675	3.685e-10	64.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_11935_0	234267.Acid_1666	9.409e-98	334.0	COG1538@1|root,COG1538@2|Bacteria,3Y4MP@57723|Acidobacteria	57723|Acidobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_11935_2	234267.Acid_1131	1.002e-57	218.0	COG3279@1|root,COG3279@2|Bacteria,3Y6CD@57723|Acidobacteria	57723|Acidobacteria	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS2_k127_11935_1	1267535.KB906767_gene4055	2.588e-65	229.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
GDHHQS2_k127_1196009_1	344747.PM8797T_07729	2.586e-191	615.0	COG2010@1|root,COG2010@2|Bacteria,2IXBJ@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt2,PSD1
GDHHQS2_k127_1196009_2	344747.PM8797T_07719	2.251e-165	535.0	COG3119@1|root,COG3119@2|Bacteria,2IXCS@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1196009_0	1267535.KB906767_gene3310	6.883e-202	649.0	COG2234@1|root,COG2234@2|Bacteria,3Y6K6@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_1196009_5	240016.ABIZ01000001_gene1504	1.519e-38	154.0	COG2382@1|root,COG2382@2|Bacteria,46TS7@74201|Verrucomicrobia,2IU61@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_1196009_4	234267.Acid_1418	6.55e-105	357.0	2F182@1|root,33U95@2|Bacteria,3Y7QP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1196009_3	1340493.JNIF01000003_gene2085	4.529e-146	471.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1201368_8	1463857.JOFZ01000002_gene4828	2.772e-51	187.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
GDHHQS2_k127_1201368_6	1267533.KB906741_gene549	2.751e-72	249.0	COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS2_k127_1201368_4	1123242.JH636434_gene3868	7.335e-87	304.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1201368_5	595460.RRSWK_06447	8.319e-77	271.0	COG1680@1|root,COG3509@1|root,COG1680@2|Bacteria,COG3509@2|Bacteria,2J04W@203682|Planctomycetes	203682|Planctomycetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
GDHHQS2_k127_1201368_0	234267.Acid_0453	5.7e-232	732.0	COG1132@1|root,COG1132@2|Bacteria,3Y2ZR@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_1201368_1	1340493.JNIF01000004_gene177	2.452e-191	622.0	COG1657@1|root,COG3391@1|root,COG1657@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14647,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	-
GDHHQS2_k127_1201368_3	234267.Acid_4939	1.582e-126	412.0	COG2013@1|root,COG2013@2|Bacteria,3Y2XF@57723|Acidobacteria	57723|Acidobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
GDHHQS2_k127_1201368_7	234267.Acid_5883	5.363e-57	201.0	COG1959@1|root,COG1959@2|Bacteria,3Y87Y@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS2_k127_1201368_2	234267.Acid_5884	1.127e-159	511.0	COG0031@1|root,COG0031@2|Bacteria,3Y45Z@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_1201368_10	682795.AciX8_2010	0.0005921	45.0	COG1629@1|root,COG4771@2|Bacteria,3Y9B2@57723|Acidobacteria,2JP74@204432|Acidobacteriia	57723|Acidobacteria	M	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1201484_0	1340493.JNIF01000003_gene2160	4.559e-319	997.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1201854_2	1041139.KB902646_gene3389	2.507e-06	59.0	COG1802@1|root,COG1802@2|Bacteria,1RBIC@1224|Proteobacteria,2U60T@28211|Alphaproteobacteria,4BB65@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_1201854_0	404589.Anae109_1665	1.091e-184	589.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_1201854_1	639283.Snov_4076	1.571e-55	206.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,3F0K5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	gci	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1209302_0	1340493.JNIF01000003_gene4293	2.053e-232	736.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1209302_1	234267.Acid_6489	6.691e-52	191.0	COG1354@1|root,COG1354@2|Bacteria,3Y458@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS2_k127_121005_5	1183438.GKIL_2620	2.612e-10	64.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
GDHHQS2_k127_121005_3	551789.ATVJ01000001_gene550	2.909e-133	443.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,43ZTI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_121005_1	234267.Acid_3444	1.191e-146	499.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_121005_2	204669.Acid345_3039	2.214e-139	461.0	28NTH@1|root,2ZBS4@2|Bacteria,3Y3NN@57723|Acidobacteria,2JIEU@204432|Acidobacteriia	204432|Acidobacteriia	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
GDHHQS2_k127_121005_4	1254432.SCE1572_09515	2.433e-48	179.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
GDHHQS2_k127_121005_0	448385.sce1437	2.595e-160	514.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
GDHHQS2_k127_1214885_0	1340493.JNIF01000003_gene2760	4.243e-295	921.0	COG2067@1|root,COG2067@2|Bacteria,3Y41G@57723|Acidobacteria	57723|Acidobacteria	I	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1214885_3	1356852.N008_02315	7.909e-79	278.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,47UAR@768503|Cytophagia	976|Bacteroidetes	E	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_1214885_1	234267.Acid_0457	1.55e-154	495.0	COG0348@1|root,COG0348@2|Bacteria,3Y3H4@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
GDHHQS2_k127_1214885_2	234267.Acid_1508	6.245e-135	437.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GDHHQS2_k127_1214885_5	1144275.COCOR_05955	2.974e-24	113.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WV4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
GDHHQS2_k127_1227520_1	631454.N177_1897	2.423e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2TTPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_01425	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_1227520_2	1128427.KB904821_gene525	1.034e-06	60.0	COG0642@1|root,COG2114@1|root,COG2203@1|root,COG3437@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G0F6@1117|Cyanobacteria,1H7AR@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaC	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_1227520_0	639283.Snov_3618	3.331e-183	579.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TQQH@28211|Alphaproteobacteria,3EYTG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_1236577_3	234267.Acid_7134	1.358e-121	401.0	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
GDHHQS2_k127_1236577_5	1267535.KB906767_gene3620	1.026e-32	132.0	COG1965@1|root,COG1965@2|Bacteria	2|Bacteria	P	Belongs to the frataxin family	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	1.16.3.1	ko:K06202,ko:K19054	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000,ko03029	-	-	iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108	Frataxin_Cyay
GDHHQS2_k127_1236577_2	234267.Acid_5926	1.045e-139	458.0	COG0635@1|root,COG0635@2|Bacteria,3Y2ZB@57723|Acidobacteria	57723|Acidobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS2_k127_1236577_1	1340493.JNIF01000003_gene2708	3.052e-145	468.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria	57723|Acidobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS2_k127_1236577_6	278963.ATWD01000001_gene1575	3.866e-18	88.0	COG1555@1|root,COG1555@2|Bacteria,3Y8EF@57723|Acidobacteria,2JNFN@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
GDHHQS2_k127_1236577_4	926566.Terro_0442	7.587e-76	276.0	COG2267@1|root,COG2267@2|Bacteria,3Y9CQ@57723|Acidobacteria,2JP6J@204432|Acidobacteriia	204432|Acidobacteriia	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1236577_9	671143.DAMO_2233	0.0009153	44.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_1236577_8	113355.CM001775_gene2010	8.419e-05	48.0	COG1598@1|root,COG1598@2|Bacteria,1G985@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_1236577_7	1094715.CM001373_gene1650	5.617e-09	64.0	COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,1S8WB@1236|Gammaproteobacteria,1JEPD@118969|Legionellales	118969|Legionellales	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_1236577_0	861299.J421_5946	2.239e-233	742.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_124725_0	926566.Terro_3580	9.597e-06	57.0	2CEAG@1|root,31NYW@2|Bacteria,3Y52E@57723|Acidobacteria,2JJI1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GDHHQS2_k127_1266360_2	234267.Acid_7537	9.217e-44	166.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria	57723|Acidobacteria	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS2_k127_1266360_0	1340493.JNIF01000004_gene393	2.797e-172	552.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS2_k127_1266360_1	234267.Acid_1067	2.883e-145	465.0	COG0329@1|root,COG0329@2|Bacteria,3Y30K@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.16	ko:K18123	ko00330,ko00630,ko01100,map00330,map00630,map01100	-	R00470,R00471	RC00307,RC00308	ko00000,ko00001,ko01000	-	-	-	DHDPS
GDHHQS2_k127_1266360_3	234267.Acid_0767	4.929e-20	94.0	COG0636@1|root,COG0636@2|Bacteria,3Y59E@57723|Acidobacteria	57723|Acidobacteria	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS2_k127_1268551_1	1122604.JONR01000032_gene93	1.983e-41	156.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,1SZEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1268551_0	234267.Acid_5471	3.497e-117	396.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_1270606_0	203124.Tery_3497	8.821e-63	232.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7
GDHHQS2_k127_1270693_1	234267.Acid_1295	1.391e-93	317.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria	57723|Acidobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
GDHHQS2_k127_1270693_3	1340493.JNIF01000003_gene3028	1e-35	139.0	28VY2@1|root,2ZHZA@2|Bacteria,3Y90R@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1270693_0	234267.Acid_1297	1.162e-97	329.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS2_k127_1270693_4	1532558.JL39_07190	1.179e-29	135.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria,4BD3I@82115|Rhizobiaceae	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_1270693_2	309807.SRU_1476	1.505e-51	192.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,1FIVI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_1271659_3	234267.Acid_1059	1.004e-10	63.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria	57723|Acidobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS2_k127_1271659_0	234267.Acid_1060	2.921e-205	664.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N,TPR_8
GDHHQS2_k127_1271659_1	234267.Acid_1061	8.006e-55	196.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria	57723|Acidobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GDHHQS2_k127_1271659_2	1340493.JNIF01000004_gene53	3.11e-40	155.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GDHHQS2_k127_1275087_0	1173028.ANKO01000170_gene3346	1.361e-89	304.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS2_k127_1281878_0	1267535.KB906767_gene1795	2.957e-161	529.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1282236_4	1340493.JNIF01000003_gene2805	3.261e-24	103.0	COG1607@1|root,COG1607@2|Bacteria,3Y53T@57723|Acidobacteria	57723|Acidobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS2_k127_1282236_3	1267535.KB906767_gene2334	1.36e-33	133.0	COG0457@1|root,COG0457@2|Bacteria,3Y99M@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1282236_0	153721.MYP_2282	1.758e-147	484.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1282236_2	234267.Acid_5534	9.85e-50	180.0	COG0347@1|root,COG0347@2|Bacteria,3Y4TF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS2_k127_1282236_1	1267535.KB906767_gene640	6.706e-93	313.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS2_k127_1285253_2	682795.AciX8_3709	9.792e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,3Y3EM@57723|Acidobacteria,2JIDA@204432|Acidobacteriia	204432|Acidobacteriia	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_1285253_1	1038869.AXAN01000004_gene1180	4.246e-138	455.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2VNS4@28216|Betaproteobacteria,1K4VU@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid peptide transporter	dtpA	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GDHHQS2_k127_1285253_0	234267.Acid_0753	3.3e-192	606.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1287124_0	1340493.JNIF01000004_gene597	1.601e-166	554.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1287124_1	234267.Acid_0472	1.597e-14	78.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
GDHHQS2_k127_1287124_2	1163671.JAGI01000002_gene3114	1.035e-05	48.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,36JIM@31979|Clostridiaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_1288193_8	1173020.Cha6605_4437	5.388e-53	203.0	COG2244@1|root,COG2244@2|Bacteria,1G07A@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
GDHHQS2_k127_1288193_0	234267.Acid_4916	0.0	1068.0	COG1629@1|root,COG4771@2|Bacteria,3Y9AT@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1288193_1	1340493.JNIF01000003_gene3950	2.723e-162	527.0	COG0471@1|root,COG0471@2|Bacteria,3Y6TC@57723|Acidobacteria	57723|Acidobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
GDHHQS2_k127_1288193_7	234267.Acid_7192	2.837e-58	207.0	COG2940@1|root,COG2940@2|Bacteria,3Y7R1@57723|Acidobacteria	57723|Acidobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS2_k127_1288193_2	1340493.JNIF01000004_gene87	4.991e-158	507.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS2_k127_1288193_3	234267.Acid_1084	1.78e-124	420.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GDHHQS2_k127_1288193_4	234267.Acid_1085	6.403e-114	374.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_1288193_11	234267.Acid_7926	1.591e-17	89.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS2_k127_1288193_10	234267.Acid_7925	2.881e-18	94.0	COG3832@1|root,COG3832@2|Bacteria,3Y94H@57723|Acidobacteria	57723|Acidobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1288193_12	111781.Lepto7376_3620	0.0004688	46.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1G5@1117|Cyanobacteria,1H794@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetratricopeptide repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7
GDHHQS2_k127_1288193_6	234267.Acid_4277	6.67e-80	273.0	2AU2S@1|root,31JP5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_1288193_9	234267.Acid_2155	7.331e-27	117.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_1288193_5	1267535.KB906767_gene3099	1.663e-110	366.0	COG0812@1|root,COG0812@2|Bacteria,3Y3AT@57723|Acidobacteria,2JIMJ@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS2_k127_1296197_2	1278073.MYSTI_02610	1.681e-18	96.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
GDHHQS2_k127_1296197_1	1278073.MYSTI_02610	4.349e-39	166.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
GDHHQS2_k127_1296197_0	1340493.JNIF01000004_gene52	8.444e-141	450.0	COG0362@1|root,COG0362@2|Bacteria,3Y990@57723|Acidobacteria	57723|Acidobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS2_k127_1297367_1	234267.Acid_3719	4.683e-26	110.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_1297367_0	1267535.KB906767_gene3601	9.199e-215	678.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria,2JICX@204432|Acidobacteriia	204432|Acidobacteriia	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoGdeHyase_C,Transket_pyr
GDHHQS2_k127_1299479_17	1267535.KB906767_gene1680	1.104e-25	121.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_1299479_11	234267.Acid_2975	1.323e-78	276.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1299479_6	497964.CfE428DRAFT_1056	4.13e-113	379.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
GDHHQS2_k127_1299479_9	234267.Acid_3773	1.805e-82	286.0	COG2372@1|root,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	-	-	3.2.1.20	ko:K01187,ko:K16915	ko00052,ko00500,ko01100,ko02010,map00052,map00500,map01100,map02010	M00246	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02000	-	GH31	-	Big_5
GDHHQS2_k127_1299479_7	1340493.JNIF01000003_gene3795	4.036e-98	327.0	COG1028@1|root,COG1028@2|Bacteria,3Y67C@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_1299479_4	1340493.JNIF01000003_gene3796	2.151e-159	509.0	COG0473@1|root,COG0473@2|Bacteria,3Y3YY@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
GDHHQS2_k127_1299479_18	292563.Cyast_0087	4.882e-14	80.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
GDHHQS2_k127_1299479_15	243365.CV_1581	1.526e-36	143.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KSG8@206351|Neisseriales	206351|Neisseriales	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_1299479_16	1485544.JQKP01000001_gene1229	8.382e-31	128.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,Response_reg
GDHHQS2_k127_1299479_10	927658.AJUM01000024_gene2582	1.747e-79	279.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,2FN6V@200643|Bacteroidia,3XJN2@558415|Marinilabiliaceae	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	ce	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
GDHHQS2_k127_1299479_5	1123242.JH636434_gene3897	3.215e-151	489.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	203682|Planctomycetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS2_k127_1299479_2	234267.Acid_4079	2.438e-190	619.0	COG0457@1|root,COG1413@1|root,COG3303@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,COG3303@2|Bacteria,3Y876@57723|Acidobacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_2,TPR_8
GDHHQS2_k127_1299479_0	1040989.AWZU01000041_gene6035	1.289e-239	753.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3JSJ1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
GDHHQS2_k127_1299479_1	1340493.JNIF01000004_gene703	9.417e-223	697.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_1299479_3	1340493.JNIF01000004_gene702	2.968e-184	595.0	COG0728@1|root,COG0728@2|Bacteria,3Y31G@57723|Acidobacteria	57723|Acidobacteria	S	virulence factor MVIN family protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS2_k127_1299479_12	234267.Acid_0817	3.361e-75	259.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria	57723|Acidobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS2_k127_1299479_13	757424.Hsero_3054	8.849e-71	253.0	COG0628@1|root,COG0628@2|Bacteria,1NFG3@1224|Proteobacteria,2W1HS@28216|Betaproteobacteria,476TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS2_k127_1299479_8	234267.Acid_4933	1.242e-90	309.0	COG2370@1|root,COG2370@2|Bacteria	2|Bacteria	O	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ,NicO
GDHHQS2_k127_1299479_14	234267.Acid_4962	7.883e-56	201.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1302249_1	234267.Acid_0496	2.833e-61	225.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS2_k127_1302249_2	1128421.JAGA01000003_gene2875	2.537e-15	82.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1302249_0	1128421.JAGA01000003_gene2874	1.664e-126	416.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1302760_5	234267.Acid_5174	6.98e-68	236.0	COG1940@1|root,COG1940@2|Bacteria,3Y62I@57723|Acidobacteria	57723|Acidobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_1302760_1	234267.Acid_3554	8.411e-117	392.0	COG2870@1|root,COG2870@2|Bacteria,3Y680@57723|Acidobacteria	57723|Acidobacteria	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS2_k127_1302760_0	234267.Acid_3555	6.711e-156	501.0	COG1915@1|root,COG1915@2|Bacteria,3Y7FB@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1302760_3	1340493.JNIF01000003_gene4381	1.601e-111	366.0	COG0546@1|root,COG0546@2|Bacteria,3Y621@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase
GDHHQS2_k127_1302760_4	1340493.JNIF01000003_gene1498	2.069e-75	259.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_1302760_2	1340493.JNIF01000003_gene1499	1.901e-112	377.0	COG0457@1|root,COG0457@2|Bacteria,3Y7CG@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_1303790_1	234267.Acid_3965	1.883e-92	328.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,CUB,Calx-beta,DUF3739,Haemagg_act,SdrD_B
GDHHQS2_k127_1303790_0	1267535.KB906767_gene4787	0.0	1315.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria,2JITI@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
GDHHQS2_k127_1305744_4	1340493.JNIF01000003_gene3111	6.664e-26	116.0	2EJ55@1|root,33CWC@2|Bacteria	2|Bacteria	S	Intracellular proteinase inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI
GDHHQS2_k127_1305744_1	234267.Acid_0858	4.998e-189	618.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1305744_0	234267.Acid_3165	8.198e-190	607.0	COG2812@1|root,COG2812@2|Bacteria,3Y3C4@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS2_k127_1305744_3	234267.Acid_3166	3.239e-33	131.0	COG0718@1|root,COG0718@2|Bacteria,3Y5CB@57723|Acidobacteria	57723|Acidobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS2_k127_1305744_2	1267535.KB906767_gene4255	9.939e-97	319.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GDHHQS2_k127_1305744_5	234267.Acid_4469	7.607e-13	68.0	COG2227@1|root,COG2227@2|Bacteria,3Y2SJ@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_1312728_1	234267.Acid_7748	2.542e-169	539.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,3Y44H@57723|Acidobacteria	57723|Acidobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
GDHHQS2_k127_1312728_0	234267.Acid_7747	1.021e-216	679.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS2_k127_1312728_3	234267.Acid_7746	5.504e-116	381.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_1312728_4	234267.Acid_7745	6.812e-106	352.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_1312728_2	926560.KE387027_gene532	1.237e-129	429.0	COG0654@1|root,COG0654@2|Bacteria,1WMEV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1312728_5	344747.PM8797T_21913	2.724e-93	314.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1317770_0	234267.Acid_0265	3.1e-244	776.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
GDHHQS2_k127_1317770_1	573370.DMR_38040	5.957e-202	661.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_1317770_4	1267535.KB906767_gene4756	1.964e-17	87.0	29WS1@1|root,30ID4@2|Bacteria,3Y5IE@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
GDHHQS2_k127_1317770_2	1267535.KB906767_gene1533	2.02e-38	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K07263	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_1325356_1	1267535.KB906767_gene3607	1.526e-211	668.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria,2JIY6@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GDHHQS2_k127_1325356_2	234267.Acid_5658	9.051e-45	183.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1325356_0	234267.Acid_7412	1.168e-233	734.0	COG1884@1|root,COG1884@2|Bacteria,3Y2QA@57723|Acidobacteria	57723|Acidobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS2_k127_1325356_4	234267.Acid_7411	3.564e-14	78.0	28WCX@1|root,2ZID8@2|Bacteria,3Y8ZH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1325356_3	1340493.JNIF01000003_gene2471	2.802e-32	128.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1325356_5	1541065.JRFE01000024_gene814	6.154e-08	56.0	COG0438@1|root,COG0438@2|Bacteria,1G24T@1117|Cyanobacteria,3VJ8I@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	rfbW	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1328321_0	401053.AciPR4_1573	1.372e-197	637.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1337079_1	234267.Acid_7196	9.622e-135	440.0	2DBA6@1|root,2Z814@2|Bacteria,3Y3NI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1337079_0	234267.Acid_7195	4.885e-143	468.0	28JQV@1|root,2Z7R2@2|Bacteria,3Y619@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1337079_2	1340493.JNIF01000003_gene4393	8.22e-86	288.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_1342464_1	743720.Psefu_2484	2.523e-09	68.0	2FA92@1|root,342HR@2|Bacteria,1NYCG@1224|Proteobacteria,1SQ6S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1342464_0	330214.NIDE3910	1.489e-46	173.0	COG3170@1|root,COG3170@2|Bacteria,3J1CW@40117|Nitrospirae	40117|Nitrospirae	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
GDHHQS2_k127_1342769_0	192952.MM_3198	1.409e-138	455.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
GDHHQS2_k127_1344083_1	395495.Lcho_1708	1.974e-56	199.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
GDHHQS2_k127_1344083_2	395495.Lcho_1708	6.15e-16	80.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
GDHHQS2_k127_1344083_0	522306.CAP2UW1_2826	1.007e-286	889.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
GDHHQS2_k127_1350468_1	1267535.KB906767_gene4238	5.972e-107	371.0	COG0329@1|root,COG0329@2|Bacteria,3Y6I2@57723|Acidobacteria,2JMAW@204432|Acidobacteriia	204432|Acidobacteriia	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1350468_9	1047013.AQSP01000133_gene2124	9.73e-06	57.0	COG1921@1|root,COG1921@2|Bacteria	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_1350468_3	234267.Acid_4576	2.061e-30	130.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_1350468_0	234267.Acid_4577	4.658e-186	596.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_1350468_5	1267534.KB906756_gene669	3.398e-17	88.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	prpB12	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS2_k127_1350468_7	661478.OP10G_2313	2.146e-12	70.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1350468_6	234267.Acid_0011	8.707e-17	82.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_1350468_2	1267535.KB906767_gene1536	8.89e-82	284.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1350468_4	1358423.N180_14670	5.935e-22	98.0	COG0673@1|root,COG0673@2|Bacteria,4NHKX@976|Bacteroidetes,1IQDV@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1353536_0	1403819.BATR01000147_gene5039	2.73e-134	434.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_1353536_2	105559.Nwat_0649	2.425e-62	219.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS2_k127_1353536_3	215803.DB30_6996	6.734e-50	183.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,4331F@68525|delta/epsilon subdivisions,2WXKR@28221|Deltaproteobacteria,2YY54@29|Myxococcales	28221|Deltaproteobacteria	C	SUF system FeS assembly protein	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS2_k127_1353536_1	234267.Acid_7701	4.183e-71	246.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_1357805_9	1267535.KB906767_gene3533	2.273e-08	56.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS2_k127_1357805_8	1340493.JNIF01000003_gene4059	1.127e-44	173.0	2C730@1|root,33CNG@2|Bacteria,3Y5XE@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1357805_6	1189619.pgond44_02793	4.924e-57	209.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1HWTG@117743|Flavobacteriia,4C2CB@83612|Psychroflexus	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS2_k127_1357805_3	234267.Acid_6425	3.872e-149	478.0	COG2896@1|root,COG2896@2|Bacteria,3Y30D@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GDHHQS2_k127_1357805_2	1340493.JNIF01000003_gene1421	8.911e-151	481.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS2_k127_1357805_1	234267.Acid_3771	1.823e-158	512.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1357805_0	234267.Acid_3771	1.642e-159	514.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1357805_7	1267535.KB906767_gene5087	9.786e-52	190.0	COG2010@1|root,COG2010@2|Bacteria,3Y8CD@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1357805_4	234267.Acid_5375	1.76e-128	424.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1357805_5	204669.Acid345_0637	3.261e-94	323.0	COG1680@1|root,COG1680@2|Bacteria,3Y7EG@57723|Acidobacteria,2JNJ4@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1357932_0	344747.PM8797T_27784	8.379e-101	340.0	COG2010@1|root,COG2010@2|Bacteria,2J2QT@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_1357932_1	497964.CfE428DRAFT_0077	0.0001442	49.0	COG1538@1|root,COG1538@2|Bacteria,46T1E@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_1364403_1	1340493.JNIF01000003_gene4150	2.199e-59	221.0	COG1470@1|root,COG4625@1|root,COG1470@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
GDHHQS2_k127_1364403_4	234267.Acid_0422	4.377e-48	180.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1364403_0	395493.BegalDRAFT_1285	2.366e-155	523.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1364403_3	221288.JH992901_gene3301	3.01e-50	194.0	COG1672@1|root,COG1672@2|Bacteria,1G15R@1117|Cyanobacteria,1JJ4U@1189|Stigonemataceae	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1364403_5	1313172.YM304_03450	7.749e-47	190.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	MA20_05265	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1364403_2	1267535.KB906767_gene457	4.459e-55	203.0	COG0457@1|root,COG0457@2|Bacteria,3Y7U6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1366998_2	1267533.KB906739_gene2470	7.405e-22	101.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_1366998_1	1340493.JNIF01000003_gene2841	7.804e-56	200.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_1366998_0	682795.AciX8_0267	3.216e-86	310.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1377093_2	234267.Acid_7195	4.366e-123	407.0	28JQV@1|root,2Z7R2@2|Bacteria,3Y619@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1377093_6	237368.SCABRO_03277	5.058e-11	66.0	COG2442@1|root,COG2442@2|Bacteria,2J4DY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_1377093_7	1499967.BAYZ01000136_gene49	3.617e-10	65.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1377093_0	1340493.JNIF01000003_gene1944	1.946e-181	578.0	COG1109@1|root,COG1109@2|Bacteria	2|Bacteria	G	phosphoglucosamine mutase activity	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_1377093_1	1340493.JNIF01000003_gene1945	1.268e-155	505.0	COG1109@1|root,COG1109@2|Bacteria	2|Bacteria	G	phosphoglucosamine mutase activity	-	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_1377093_4	1340493.JNIF01000003_gene1946	5.894e-70	243.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria	57723|Acidobacteria	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_1377093_3	1121481.AUAS01000007_gene1195	2.834e-100	352.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_1377093_5	1267535.KB906767_gene676	6.298e-46	171.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_1377528_1	1034943.BN1094_03777	3.465e-17	89.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1JDIC@118969|Legionellales	118969|Legionellales	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
GDHHQS2_k127_1377528_2	686340.Metal_2759	7.661e-08	55.0	COG1018@1|root,COG1018@2|Bacteria,1RAS4@1224|Proteobacteria,1SXIT@1236|Gammaproteobacteria,1XG2E@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
GDHHQS2_k127_1377528_0	243231.GSU2811	4.397e-147	471.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1378880_0	344747.PM8797T_21603	1.847e-127	433.0	COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_1378880_4	234267.Acid_4362	1.022e-35	141.0	COG0457@1|root,COG0457@2|Bacteria,3Y4XQ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_1378880_1	1340493.JNIF01000004_gene1009	1.035e-123	406.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria	57723|Acidobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GDHHQS2_k127_1378880_2	344747.PM8797T_20763	6.454e-119	402.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
GDHHQS2_k127_1378880_3	234267.Acid_4215	9.809e-116	382.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_1380241_3	1046714.AMRX01000001_gene1281	3.219e-15	75.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,463YB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Oxidoreductase	neoG	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
GDHHQS2_k127_1380241_1	379066.GAU_2100	5.571e-115	378.0	COG3622@1|root,COG3622@2|Bacteria,1ZT2P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_1380241_2	861299.J421_4120	5.096e-71	251.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS2_k127_1380241_0	861299.J421_4121	6.075e-228	723.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS2_k127_1386997_4	1123278.KB893574_gene6158	4.599e-48	173.0	COG0823@1|root,COG0823@2|Bacteria,4NM2C@976|Bacteroidetes,47NM2@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1386997_2	443143.GM18_1305	3.379e-78	276.0	COG4872@1|root,COG4872@2|Bacteria,1NF4D@1224|Proteobacteria,42XRT@68525|delta/epsilon subdivisions,2WXTA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
GDHHQS2_k127_1386997_5	234267.Acid_2553	1.944e-36	154.0	2FC9W@1|root,344DJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1386997_1	1340493.JNIF01000003_gene3268	4.32e-127	418.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_1386997_0	1037409.BJ6T_42530	1.153e-181	586.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_1386997_3	1227739.Hsw_1682	8.074e-70	243.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	ComFC	-	-	-	-	-	-	-	-	-	-	-	DZR,Pribosyltran,zinc_ribbon_2
GDHHQS2_k127_1398083_0	1007105.PT7_0650	3.452e-95	327.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_1398083_3	1123504.JQKD01000012_gene1288	7.348e-57	204.0	COG3777@1|root,COG3777@2|Bacteria,1P215@1224|Proteobacteria	1224|Proteobacteria	S	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
GDHHQS2_k127_1398083_2	1123504.JQKD01000012_gene1287	4.279e-76	258.0	COG3777@1|root,COG3777@2|Bacteria,1RIJT@1224|Proteobacteria	1224|Proteobacteria	S	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1398083_1	1123504.JQKD01000012_gene1284	4.536e-91	306.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VM5F@28216|Betaproteobacteria,4ABQW@80864|Comamonadaceae	28216|Betaproteobacteria	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
GDHHQS2_k127_1398512_4	1047013.AQSP01000076_gene1470	1.919e-39	148.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
GDHHQS2_k127_1398512_5	391616.OA238_c42550	3.314e-21	96.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
GDHHQS2_k127_1398512_1	1340493.JNIF01000003_gene3565	5.384e-56	207.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1398512_0	278963.ATWD01000001_gene2919	5.473e-125	432.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1398512_2	278963.ATWD01000001_gene2919	3.311e-51	196.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1398512_3	502025.Hoch_2959	6.47e-45	166.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS2_k127_1398753_3	1267535.KB906767_gene819	1.227e-70	246.0	COG0311@1|root,COG0311@2|Bacteria,3Y4GN@57723|Acidobacteria,2JJ3V@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
GDHHQS2_k127_1398753_2	1267535.KB906767_gene820	1.206e-149	477.0	COG0214@1|root,COG0214@2|Bacteria,3Y3ST@57723|Acidobacteria,2JKN5@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
GDHHQS2_k127_1398753_1	234267.Acid_0291	6.224e-175	564.0	COG1167@1|root,COG1167@2|Bacteria,3Y4RE@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
GDHHQS2_k127_1398753_0	234267.Acid_3470	1.007e-214	684.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1403417_0	1123242.JH636434_gene3868	1.78e-68	256.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1403417_2	204669.Acid345_0608	1.743e-35	147.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_1403417_1	234267.Acid_0586	1.92e-36	151.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria	57723|Acidobacteria	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS2_k127_1421486_2	234267.Acid_1535	1.038e-102	349.0	COG0739@1|root,COG0739@2|Bacteria,3Y3GS@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_1421486_4	234267.Acid_6405	3.104e-46	172.0	2C62N@1|root,32TCB@2|Bacteria,3Y55K@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1421486_1	234267.Acid_6406	2.306e-114	375.0	COG4974@1|root,COG4974@2|Bacteria,3Y3D0@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_1421486_0	1267535.KB906767_gene4302	2.274e-130	433.0	COG0617@1|root,COG0617@2|Bacteria,3Y3U6@57723|Acidobacteria,2JIF4@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family	-	-	-	-	-	-	-	-	-	-	-	-	PolyA_pol
GDHHQS2_k127_1421486_3	1340493.JNIF01000003_gene3565	2.151e-96	333.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1422623_2	1267535.KB906767_gene5291	8.978e-50	184.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_25
GDHHQS2_k127_1422623_0	234267.Acid_1820	3.211e-155	504.0	COG2271@1|root,COG2271@2|Bacteria,3Y6PG@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_1422623_3	234267.Acid_6359	1.635e-33	133.0	COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria	57723|Acidobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS2_k127_1422623_1	1396418.BATQ01000085_gene1127	3.464e-57	205.0	COG2258@1|root,COG2258@2|Bacteria,46ZIX@74201|Verrucomicrobia,2IV4B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
GDHHQS2_k127_1422623_4	1108045.GORHZ_203_00030	6.097e-12	78.0	2C62F@1|root,335K1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1423399_0	401053.AciPR4_0741	2.911e-138	461.0	COG1629@1|root,COG1629@2|Bacteria,3Y39E@57723|Acidobacteria,2JIU9@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1423774_2	330214.NIDE3921	7.309e-11	68.0	29TFP@1|root,30ENV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GDHHQS2_k127_1423774_0	1267535.KB906767_gene1676	6.728e-42	157.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_1423774_3	1996.JOFO01000018_gene5411	1.139e-05	54.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4EIQM@85012|Streptosporangiales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GDHHQS2_k127_1423774_1	234267.Acid_7891	2.146e-11	64.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_1425158_0	234267.Acid_2974	7.315e-170	553.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1429663_4	399795.CtesDRAFT_PD4433	0.0002392	48.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2VJR1@28216|Betaproteobacteria,4AACR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
GDHHQS2_k127_1429663_3	234267.Acid_4191	1.173e-47	176.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_1429663_1	234267.Acid_4577	3.677e-170	556.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_1429663_0	234267.Acid_5921	1.232e-240	782.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1429663_2	1340493.JNIF01000003_gene3568	9.457e-72	254.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_1429888_2	1242864.D187_001437	9.883e-19	88.0	COG2374@1|root,COG2374@2|Bacteria,1QTNH@1224|Proteobacteria,43809@68525|delta/epsilon subdivisions,2X3AA@28221|Deltaproteobacteria,2YV3X@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1429888_1	234267.Acid_3440	3.245e-66	230.0	28NN4@1|root,2ZBNJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1429888_0	1396141.BATP01000020_gene22	3.015e-95	331.0	COG1404@1|root,COG3469@1|root,COG1404@2|Bacteria,COG3469@2|Bacteria,46XKP@74201|Verrucomicrobia,2IW57@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS2_k127_1436142_2	338966.Ppro_1841	2.383e-32	133.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
GDHHQS2_k127_1436142_4	1267535.KB906767_gene5245	2.821e-08	61.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1436142_0	595460.RRSWK_06974	4.417e-78	278.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
GDHHQS2_k127_1436142_1	1340493.JNIF01000003_gene2614	2.009e-68	233.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_1441652_0	204669.Acid345_0638	1.286e-103	364.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HY@57723|Acidobacteria,2JIYZ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1445977_1	344747.PM8797T_11556	2.344e-51	188.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1445977_0	314230.DSM3645_01791	1.054e-122	415.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWWI@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
GDHHQS2_k127_1450188_5	1267535.KB906767_gene4839	1.375e-38	154.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene4839|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1450188_1	1267535.KB906767_gene3810	2.49e-183	587.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1450188_6	1382356.JQMP01000003_gene1979	2.801e-31	134.0	COG1720@1|root,COG2191@1|root,COG1720@2|Bacteria,COG2191@2|Bacteria,2GAT9@200795|Chloroflexi,27YTY@189775|Thermomicrobia	189775|Thermomicrobia	C	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	FmdE,UPF0066
GDHHQS2_k127_1450188_4	1267535.KB906767_gene2372	5.116e-135	437.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia	204432|Acidobacteriia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GDHHQS2_k127_1450188_0	1267535.KB906767_gene2371	1.262e-281	878.0	COG1657@1|root,COG1657@2|Bacteria,3Y37N@57723|Acidobacteria,2JIJP@204432|Acidobacteriia	204432|Acidobacteriia	I	Squalene-hopene cyclase C-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
GDHHQS2_k127_1450188_2	1340493.JNIF01000003_gene3883	6.798e-167	531.0	COG0535@1|root,COG0535@2|Bacteria,3Y2JV@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
GDHHQS2_k127_1450188_3	1267535.KB906767_gene2370	8.005e-138	446.0	COG0451@1|root,COG0451@2|Bacteria,3Y41S@57723|Acidobacteria,2JIV2@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM hopanoid-associated sugar epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS2_k127_1450188_7	234267.Acid_1262	8.015e-13	78.0	COG0775@1|root,COG0775@2|Bacteria,3Y5BZ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphorylase superfamily	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_1451277_1	1538295.JY96_08495	1.125e-163	522.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2VKIA@28216|Betaproteobacteria,1KPCA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
GDHHQS2_k127_1451277_4	1519464.HY22_10645	4.297e-84	302.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
GDHHQS2_k127_1451277_2	1120705.FG95_00974	2.166e-127	422.0	COG3119@1|root,COG3119@2|Bacteria,1MX3Z@1224|Proteobacteria,2V7VC@28211|Alphaproteobacteria,2K4YT@204457|Sphingomonadales	204457|Sphingomonadales	P	Sulfatase	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_1451277_5	743722.Sph21_1005	6.478e-82	300.0	28VPU@1|root,2ZHRS@2|Bacteria,4NJWU@976|Bacteroidetes,1IQRH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1451277_3	1379270.AUXF01000007_gene963	6.209e-125	428.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
GDHHQS2_k127_1451277_7	1278073.MYSTI_01766	2.816e-10	67.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1451277_0	1267535.KB906767_gene3956	1.063e-201	632.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS2_k127_1451277_6	1267535.KB906767_gene3957	3.103e-18	85.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria	57723|Acidobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS2_k127_1452176_3	1395587.P364_0120850	7.406e-22	100.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,26RKY@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_1452176_1	316274.Haur_2562	2.629e-46	176.0	COG1280@1|root,COG1280@2|Bacteria,2G9QD@200795|Chloroflexi,377BI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS2_k127_1452176_2	379066.GAU_2726	2.487e-41	164.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_1452176_0	1267535.KB906767_gene629	1.904e-103	341.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_1456327_2	1305737.JAFX01000001_gene2430	4.236e-08	59.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
GDHHQS2_k127_1456327_0	1340493.JNIF01000003_gene1883	1.082e-142	465.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_1456327_1	344747.PM8797T_17554	3.361e-64	227.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	-	1.3.1.14	ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,DHO_dh,NAD_binding_1
GDHHQS2_k127_1460081_0	1267535.KB906767_gene1167	1.423e-43	168.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1460081_1	765420.OSCT_0783	2.006e-20	102.0	COG0457@1|root,COG5427@1|root,COG0457@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,37551@32061|Chloroflexia	32061|Chloroflexia	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
GDHHQS2_k127_1473457_2	234267.Acid_1098	1.426e-06	51.0	COG2755@1|root,COG2755@2|Bacteria,3Y99T@57723|Acidobacteria	57723|Acidobacteria	E	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
GDHHQS2_k127_1473457_1	639030.JHVA01000001_gene1333	1.382e-07	55.0	COG2755@1|root,COG2755@2|Bacteria,3Y6H8@57723|Acidobacteria,2JM84@204432|Acidobacteriia	204432|Acidobacteriia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_1473457_0	1267535.KB906767_gene1405	8.025e-74	265.0	COG1629@1|root,COG4771@2|Bacteria,3Y9A9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1487671_1	1144275.COCOR_04230	0.0001283	47.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS2_k127_1487671_0	234267.Acid_0606	3.52e-252	788.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria	57723|Acidobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_1489161_8	1340493.JNIF01000003_gene3723	3.494e-30	130.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS2_k127_1489161_0	234267.Acid_7310	3.567e-203	644.0	COG0773@1|root,COG0773@2|Bacteria,3Y304@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1489161_7	234267.Acid_7311	4.281e-121	400.0	COG0707@1|root,COG0707@2|Bacteria,3Y48B@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS2_k127_1489161_6	1267535.KB906767_gene2562	6.71e-127	420.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_1489161_4	234267.Acid_7313	1.11e-153	500.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1489161_2	1340493.JNIF01000003_gene3728	3.997e-171	551.0	COG0472@1|root,COG0472@2|Bacteria,3Y2ZH@57723|Acidobacteria	57723|Acidobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS2_k127_1489161_5	234267.Acid_7315	3.027e-142	467.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria	57723|Acidobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1489161_1	234267.Acid_7316	1.27e-182	586.0	COG0769@1|root,COG0769@2|Bacteria,3Y38W@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1489161_3	234267.Acid_7317	9.593e-158	515.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria	57723|Acidobacteria	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
GDHHQS2_k127_1492268_4	331113.SNE_A05920	2.68e-23	105.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
GDHHQS2_k127_1492268_1	570952.ATVH01000004_gene2592	1.454e-259	812.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JQ5K@204441|Rhodospirillales	204441|Rhodospirillales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_1492268_5	525904.Tter_1585	4.533e-15	79.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GDHHQS2_k127_1492268_2	1340493.JNIF01000004_gene143	2.106e-70	244.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS2_k127_1492268_0	204669.Acid345_2995	5.999e-262	816.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria,2JIRX@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_1492268_3	204669.Acid345_2996	6.98e-35	136.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS2_k127_1495537_2	1340493.JNIF01000003_gene4081	4.813e-120	389.0	COG3959@1|root,COG3959@2|Bacteria,3Y4PX@57723|Acidobacteria	57723|Acidobacteria	G	1-deoxy-D-xylulose-5-phosphate synthase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS2_k127_1495537_0	234267.Acid_2452	3.74e-134	434.0	COG3958@1|root,COG3958@2|Bacteria,3Y7P5@57723|Acidobacteria	57723|Acidobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_1495537_1	886293.Sinac_5994	4.602e-131	434.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1495537_3	1267535.KB906767_gene5367	8.494e-61	224.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5367|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1504365_5	639030.JHVA01000001_gene1886	4.776e-26	109.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1504365_11	1032480.MLP_45930	1.759e-10	63.0	COG1414@1|root,COG1414@2|Bacteria,2I3CC@201174|Actinobacteria	201174|Actinobacteria	K	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS2_k127_1504365_13	344747.PM8797T_03414	0.0002458	47.0	COG5012@1|root,COG5012@2|Bacteria,2IZ1E@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,HTH_17
GDHHQS2_k127_1504365_12	768671.ThimaDRAFT_4601	1.837e-05	53.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07713,ko:K07715	ko02020,ko02024,map02020,map02024	M00499,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_1504365_7	1038866.KB902774_gene2221	1.336e-21	107.0	COG4932@1|root,COG5563@1|root,COG4932@2|Bacteria,COG5563@2|Bacteria,1N5JV@1224|Proteobacteria,2UD1J@28211|Alphaproteobacteria,3K0ME@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1504365_2	234267.Acid_5169	3.694e-97	327.0	COG1994@1|root,COG1994@2|Bacteria,3Y4IT@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1504365_4	1340493.JNIF01000003_gene4518	8.237e-47	170.0	COG0776@1|root,COG0776@2|Bacteria,3Y55Y@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS2_k127_1504365_3	234267.Acid_5167	1.123e-48	184.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	FCD,Flavin_Reduct
GDHHQS2_k127_1504365_0	234267.Acid_2211	2.446e-177	574.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_1504365_9	1288484.APCS01000025_gene2498	3.635e-16	79.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS2_k127_1504365_10	1123368.AUIS01000021_gene982	8.764e-12	70.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,1T8KZ@1236|Gammaproteobacteria,2ND3B@225057|Acidithiobacillales	225057|Acidithiobacillales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS2_k127_1504365_6	1123253.AUBD01000001_gene1684	8.488e-23	103.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1X8FN@135614|Xanthomonadales	135614|Xanthomonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS2_k127_1504365_1	234267.Acid_1090	5.604e-152	501.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria	57723|Acidobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS2_k127_1504365_8	234267.Acid_1089	2.147e-17	85.0	COG1847@1|root,COG1847@2|Bacteria,3Y52C@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	R3H
GDHHQS2_k127_1515440_2	1340493.JNIF01000003_gene2460	1.698e-149	480.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS2_k127_1515440_3	234267.Acid_6218	1.971e-108	359.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_1515440_6	1340493.JNIF01000003_gene2458	7.325e-21	99.0	2EKYQ@1|root,33EN7@2|Bacteria,3Y5T5@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1515440_4	1340493.JNIF01000003_gene1818	1.689e-36	145.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene1818|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1515440_0	1340493.JNIF01000003_gene1819	0.0	1447.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
GDHHQS2_k127_1515440_1	234267.Acid_2696	8.951e-228	741.0	COG0726@1|root,COG3227@1|root,COG3386@1|root,COG4719@1|root,COG0726@2|Bacteria,COG3227@2|Bacteria,COG3386@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K14274,ko:K20274	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF11,DUF5122,FTP,He_PIG,NHL,Peptidase_M36,SGL
GDHHQS2_k127_1515440_7	497964.CfE428DRAFT_6429	7.142e-14	76.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
GDHHQS2_k127_1515440_5	497964.CfE428DRAFT_6429	6.704e-26	109.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
GDHHQS2_k127_1524461_0	234267.Acid_1742	1.497e-185	587.0	COG0457@1|root,COG0457@2|Bacteria,3Y7F4@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1524461_1	1267533.KB906739_gene2502	1.568e-58	223.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_1525896_6	1379270.AUXF01000005_gene535	9.743e-07	60.0	COG1680@1|root,COG1680@2|Bacteria,1ZUKU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1525896_3	717606.PaecuDRAFT_4690	1.326e-28	123.0	COG1680@1|root,COG4615@1|root,COG1680@2|Bacteria,COG4615@2|Bacteria,1TRPT@1239|Firmicutes,4HG2G@91061|Bacilli,26U5R@186822|Paenibacillaceae	91061|Bacilli	V	beta-lactamase	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran,Beta-lactamase
GDHHQS2_k127_1525896_4	1089547.KB913013_gene761	5.081e-16	83.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_1525896_1	251221.35210936	2.279e-190	612.0	COG1574@1|root,COG1574@2|Bacteria,1G40U@1117|Cyanobacteria	1117|Cyanobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_1525896_0	886293.Sinac_2520	9.647e-270	850.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS2_k127_1525896_5	886293.Sinac_3612	3.844e-08	55.0	COG2152@1|root,COG2152@2|Bacteria,2IYI2@203682|Planctomycetes	203682|Planctomycetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
GDHHQS2_k127_1525896_2	639030.JHVA01000001_gene604	1.619e-85	289.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
GDHHQS2_k127_1533872_2	1340493.JNIF01000003_gene2004	2.042e-112	377.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_1533872_0	234267.Acid_3201	1.315e-163	529.0	COG2755@1|root,COG2755@2|Bacteria,3Y2P4@57723|Acidobacteria	57723|Acidobacteria	E	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
GDHHQS2_k127_1533872_3	1123073.KB899245_gene23	6.533e-51	207.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_1533872_1	1045855.DSC_03395	4.245e-119	396.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_1540107_0	1340493.JNIF01000003_gene2329	3.627e-284	891.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_1540107_7	234267.Acid_3368	1.028e-15	83.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1540107_3	1122179.KB890423_gene2365	2.552e-85	302.0	COG0296@1|root,COG1404@1|root,COG0296@2|Bacteria,COG1404@2|Bacteria,4NJ7Z@976|Bacteroidetes,1IZWQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
GDHHQS2_k127_1540107_5	1267533.KB906738_gene2330	2.485e-68	250.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS2_k127_1540107_1	1267534.KB906757_gene1130	1.711e-131	432.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS2_k127_1540107_6	1123073.KB899242_gene1520	9.581e-20	98.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	4.4.1.3,5.3.3.19	ko:K16953,ko:K19547	ko00920,ko01130,map00920,map01130	M00787	R02574	RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Arg_Hydrox,Cupin_1,Cupin_2
GDHHQS2_k127_1540107_4	1267533.KB906733_gene3447	7.199e-74	271.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS2_k127_1540107_2	1267535.KB906767_gene1639	1.708e-127	429.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1546711_3	1340493.JNIF01000003_gene1603	4.453e-29	119.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS2_k127_1546711_5	234267.Acid_1015	0.000488	48.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_1546711_2	1267535.KB906767_gene2855	1.516e-44	168.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat,TonB_dep_Rec
GDHHQS2_k127_1546711_1	234267.Acid_4051	9.369e-147	476.0	COG0624@1|root,COG0624@2|Bacteria,3Y3F2@57723|Acidobacteria	2|Bacteria	E	TIGRFAM amidase, hydantoinase carbamoylase	amaB	-	3.5.1.116,3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016,ko:K18151	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00469,R00905,R02423,R04666	RC00064,RC00096,RC00153,RC02798,RC02805	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_1546711_4	1366050.N234_10750	0.0002427	46.0	COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,2VUPJ@28216|Betaproteobacteria,1KAK7@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS2_k127_1546711_0	234267.Acid_7061	1.143e-194	613.0	COG0673@1|root,COG0673@2|Bacteria,3Y78W@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1548193_1	344747.PM8797T_14519	2.171e-82	283.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
GDHHQS2_k127_1548193_0	1267535.KB906767_gene4235	2.616e-220	702.0	COG1506@1|root,COG1506@2|Bacteria,3Y6QI@57723|Acidobacteria	57723|Acidobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1548193_2	1449049.JONW01000005_gene1724	4.153e-09	61.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TXCE@28211|Alphaproteobacteria,2KI1F@204458|Caulobacterales	204458|Caulobacterales	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
GDHHQS2_k127_1548193_3	153948.NAL212_0080	8.131e-09	66.0	COG4974@1|root,COG4974@2|Bacteria,1R43B@1224|Proteobacteria,2VNAM@28216|Betaproteobacteria,373JF@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
GDHHQS2_k127_1559398_2	234267.Acid_5180	7.915e-63	220.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
GDHHQS2_k127_1559398_3	234267.Acid_5179	7.97e-47	176.0	COG0779@1|root,COG0779@2|Bacteria,3Y528@57723|Acidobacteria	57723|Acidobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
GDHHQS2_k127_1559398_1	204669.Acid345_0722	7.031e-89	308.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria,2JI94@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1559398_0	1267533.KB906740_gene380	6.942e-91	316.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1559398_4	234267.Acid_7025	8.255e-17	80.0	2F5GG@1|root,33Y23@2|Bacteria,3Y7UU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1563197_4	234267.Acid_7687	9.016e-63	218.0	COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_1563197_3	1340493.JNIF01000003_gene1505	2.366e-74	262.0	2F2X8@1|root,33VSU@2|Bacteria,3Y7XB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1563197_2	234267.Acid_1391	3.037e-130	428.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CTP_transf_3,HNH_4,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_1563197_0	1340493.JNIF01000003_gene2575	5.484e-249	809.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1563197_1	234267.Acid_1653	8.098e-206	649.0	COG0372@1|root,COG0372@2|Bacteria,3Y32J@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_1563197_5	234267.Acid_0288	8.745e-32	134.0	COG0394@1|root,COG0394@2|Bacteria,3Y8RC@57723|Acidobacteria	57723|Acidobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
GDHHQS2_k127_1566027_2	1340493.JNIF01000003_gene1728	1.766e-48	177.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
GDHHQS2_k127_1566027_0	234267.Acid_4586	2.8e-117	394.0	COG0860@1|root,COG3266@1|root,COG0860@2|Bacteria,COG3266@2|Bacteria,3Y3M0@57723|Acidobacteria	57723|Acidobacteria	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
GDHHQS2_k127_1566027_3	234267.Acid_5312	3.526e-29	117.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS2_k127_1566027_1	1340493.JNIF01000003_gene4574	1.669e-54	193.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1573339_11	661478.OP10G_0383	0.0009684	46.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1573339_3	1340493.JNIF01000003_gene1796	8.456e-126	414.0	COG1680@1|root,COG1680@2|Bacteria,3Y7YT@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1573339_0	1340493.JNIF01000003_gene1716	5.586e-206	648.0	COG0621@1|root,COG0621@2|Bacteria,3Y2GT@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS2_k127_1573339_5	234267.Acid_6705	5.708e-83	277.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria	57723|Acidobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS2_k127_1573339_10	1267535.KB906767_gene804	1.767e-07	65.0	COG4409@1|root,COG5563@1|root,COG4409@2|Bacteria,COG5563@2|Bacteria,3Y9G0@57723|Acidobacteria,2JNS2@204432|Acidobacteriia	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	CP_1076	-	3.2.1.52	ko:K12373,ko:K21449	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko02000,ko03110	1.B.40.2	GH20	-	BNR_2,DUF1929
GDHHQS2_k127_1573339_8	1123073.KB899241_gene2586	3.345e-47	196.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
GDHHQS2_k127_1573339_4	234267.Acid_7057	3.097e-103	349.0	COG0859@1|root,COG0859@2|Bacteria,3Y794@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GDHHQS2_k127_1573339_2	234267.Acid_7058	1.383e-145	470.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_1573339_7	234267.Acid_7059	3.204e-53	192.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria	57723|Acidobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,Glyoxalase_4
GDHHQS2_k127_1573339_1	1267535.KB906767_gene1561	1.147e-169	543.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS2_k127_1573339_6	1340493.JNIF01000003_gene4549	2.791e-78	268.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS2_k127_1578651_1	234267.Acid_3723	2.35e-41	156.0	COG0457@1|root,COG0457@2|Bacteria,3Y7T2@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS2_k127_1578651_0	234267.Acid_6591	7.656e-309	955.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS2_k127_1578651_2	1267535.KB906767_gene3327	6.058e-37	149.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	pspE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_1578651_3	1340493.JNIF01000004_gene1097	4.241e-24	109.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	1340493.JNIF01000004_gene1097|-	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1583416_6	1267533.KB906736_gene853	0.000215	44.0	COG0274@1|root,COG0274@2|Bacteria,3Y2Q4@57723|Acidobacteria,2JHNS@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS2_k127_1583416_0	1267535.KB906767_gene2157	7.302e-211	670.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
GDHHQS2_k127_1583416_1	234267.Acid_2187	6.715e-178	565.0	COG0019@1|root,COG0019@2|Bacteria,3Y2W4@57723|Acidobacteria	57723|Acidobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS2_k127_1583416_4	234267.Acid_5901	3.347e-119	391.0	COG0450@1|root,COG0450@2|Bacteria,3Y444@57723|Acidobacteria	57723|Acidobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
GDHHQS2_k127_1583416_5	1267534.KB906757_gene967	1.335e-06	53.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1583416_3	1340493.JNIF01000004_gene280	2.117e-142	467.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,PD40,PSCyt1,WD40
GDHHQS2_k127_1583416_2	1340493.JNIF01000004_gene279	1.44e-145	490.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
GDHHQS2_k127_1584591_0	1340493.JNIF01000003_gene1469	1.054e-111	376.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria	57723|Acidobacteria	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
GDHHQS2_k127_1584591_1	234267.Acid_2454	2.404e-23	104.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_2454|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_1591863_2	1385935.N836_09650	2.09e-51	190.0	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria,1HFHB@1150|Oscillatoriales	1117|Cyanobacteria	L	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
GDHHQS2_k127_1591863_7	483215.BACFIN_05743	2.576e-12	69.0	COG3293@1|root,2ZJP3@2|Bacteria,4NS7F@976|Bacteroidetes,2G058@200643|Bacteroidia,4AWEJ@815|Bacteroidaceae	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
GDHHQS2_k127_1591863_0	1340493.JNIF01000003_gene1952	0.0	1121.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
GDHHQS2_k127_1591863_1	1340493.JNIF01000003_gene1953	8.621e-96	336.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_1591863_3	234267.Acid_0413	2.597e-39	154.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_16815	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GDHHQS2_k127_1591863_4	742159.HMPREF0004_1497	7.737e-21	96.0	COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,2VWKG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_1591863_6	1123401.JHYQ01000022_gene1105	5.343e-14	72.0	COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,1S686@1236|Gammaproteobacteria,4633X@72273|Thiotrichales	72273|Thiotrichales	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_1591863_5	1038862.KB893886_gene2	4.888e-19	91.0	COG2253@1|root,COG2253@2|Bacteria,1NJT9@1224|Proteobacteria,2U243@28211|Alphaproteobacteria,3JV53@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS2_k127_1591863_9	366394.Smed_5453	2.133e-05	50.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,2U238@28211|Alphaproteobacteria,4BDNT@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_3_N,AbiEi_4
GDHHQS2_k127_1591863_8	240015.ACP_3278	9.996e-12	70.0	COG1629@1|root,COG1629@2|Bacteria,3Y66W@57723|Acidobacteria,2JKRP@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1603028_4	926559.JoomaDRAFT_0342	1.846e-37	149.0	2ABHC@1|root,310YH@2|Bacteria,4NY40@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1603028_3	1379270.AUXF01000002_gene1393	1.74e-49	181.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS2_k127_1603028_2	656024.FsymDg_0185	6.16e-54	202.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS2_k127_1603028_0	234267.Acid_7030	8.387e-123	404.0	COG0460@1|root,COG0460@2|Bacteria	2|Bacteria	E	homoserine dehydrogenase activity	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
GDHHQS2_k127_1603028_1	234267.Acid_0738	5.17e-112	374.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
GDHHQS2_k127_1606454_1	1096546.WYO_0651	7.328e-54	199.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS2_k127_1606454_0	318996.AXAZ01000001_gene4884	3.364e-161	515.0	COG4663@1|root,COG4663@2|Bacteria,1R40U@1224|Proteobacteria,2U3KB@28211|Alphaproteobacteria,3K34G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
GDHHQS2_k127_1615899_2	234267.Acid_4552	1.577e-48	181.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS2_k127_1615899_0	234267.Acid_6984	3.444e-147	473.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_1615899_1	234267.Acid_6983	3.391e-126	408.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_1624539_3	1123060.JONP01000024_gene2528	5.22e-15	78.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,2JY55@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_1624539_1	266779.Meso_3537	5.677e-59	211.0	COG0662@1|root,COG0662@2|Bacteria,1QU63@1224|Proteobacteria,2TW18@28211|Alphaproteobacteria,43Q5D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_1624539_0	504832.OCAR_7381	3.157e-83	284.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,3JRK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_18175	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_1624539_2	196367.JNFG01000018_gene4369	1.081e-22	101.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2VJFB@28216|Betaproteobacteria,1K3DM@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_1625529_2	1340493.JNIF01000003_gene2587	3.756e-134	438.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_1625529_1	234267.Acid_5992	2.109e-136	457.0	COG0842@1|root,COG0842@2|Bacteria,3Y73W@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_1625529_0	234267.Acid_5012	6.154e-291	900.0	COG0008@1|root,COG0008@2|Bacteria,3Y7DS@57723|Acidobacteria	57723|Acidobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
GDHHQS2_k127_1635697_0	682795.AciX8_0335	1.474e-219	706.0	COG2304@1|root,COG2304@2|Bacteria,3Y5S3@57723|Acidobacteria	57723|Acidobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GDHHQS2_k127_1635697_2	682795.AciX8_0336	4.536e-121	411.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19693	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Reg_prop
GDHHQS2_k127_1635697_3	1267535.KB906767_gene4207	7.869e-50	186.0	COG2134@1|root,COG2134@2|Bacteria,3Y7SW@57723|Acidobacteria	57723|Acidobacteria	I	cdp-diacylglycerol pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1635697_1	1340493.JNIF01000004_gene108	2.381e-212	668.0	COG2721@1|root,COG2721@2|Bacteria,3Y6SX@57723|Acidobacteria	57723|Acidobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
GDHHQS2_k127_1636823_6	221360.RS9917_13315	3.611e-31	126.0	COG3666@1|root,COG3666@2|Bacteria,1GEUC@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
GDHHQS2_k127_1636823_8	714943.Mucpa_0351	3.664e-12	74.0	COG3464@1|root,COG3464@2|Bacteria,4NR8V@976|Bacteroidetes	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1636823_10	1108045.GORHZ_066_00010	5.271e-07	61.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS2_k127_1636823_1	234267.Acid_6308	2.545e-118	388.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_1636823_2	66373.JOFQ01000010_gene928	2.462e-105	348.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GDHHQS2_k127_1636823_3	1123023.JIAI01000008_gene1272	3.893e-99	331.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4E0RY@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS2_k127_1636823_5	234267.Acid_5527	5.467e-49	178.0	COG2967@1|root,COG2967@2|Bacteria	2|Bacteria	P	mitochondrion morphogenesis	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
GDHHQS2_k127_1636823_0	234267.Acid_2598	2.061e-137	442.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria	57723|Acidobacteria	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS2_k127_1636823_4	479434.Sthe_3474	1.978e-93	323.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_1636823_7	234267.Acid_4962	2.057e-15	81.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_163886_1	1267535.KB906767_gene5111	5.836e-180	569.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria,2JINJ@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_163886_0	1267535.KB906767_gene3348	4.152e-230	722.0	COG1012@1|root,COG1012@2|Bacteria,3Y37W@57723|Acidobacteria,2JHJP@204432|Acidobacteriia	204432|Acidobacteriia	C	Delta-1-pyrroline-5-carboxylate dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS2_k127_163886_3	234267.Acid_1140	3.038e-13	72.0	COG4980@1|root,COG4980@2|Bacteria,3Y8W2@57723|Acidobacteria	57723|Acidobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS2_k127_163886_2	234267.Acid_6834	1.047e-126	417.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_163986_2	234267.Acid_2227	6.499e-74	260.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS2_k127_163986_0	234267.Acid_2226	0.0	1062.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_163986_3	867845.KI911784_gene3219	1.106e-66	231.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_163986_1	1396141.BATP01000005_gene5986	1.023e-74	258.0	COG2267@1|root,COG2267@2|Bacteria,46XEA@74201|Verrucomicrobia,2IVN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1647148_4	234267.Acid_2537	2.017e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,3Y5RY@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_1647148_5	234267.Acid_2539	5.4e-39	158.0	2DJMQ@1|root,32UDD@2|Bacteria,3Y57W@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1647148_1	1151127.KB906325_gene4535	9.369e-122	425.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YT39@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_9
GDHHQS2_k127_1647148_2	1210884.HG799465_gene12146	1.884e-70	254.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_1647148_6	266117.Rxyl_2362	1.159e-24	106.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4CTTA@84995|Rubrobacteria	84995|Rubrobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_1647148_0	234267.Acid_6228	8.724e-159	506.0	COG1088@1|root,COG1088@2|Bacteria,3Y3E7@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_1647148_3	1340493.JNIF01000004_gene171	2.947e-56	199.0	COG1209@1|root,COG1209@2|Bacteria,3Y2ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_1654628_2	395961.Cyan7425_1024	7.531e-39	150.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
GDHHQS2_k127_1654628_1	395961.Cyan7425_1025	1.986e-52	201.0	COG1493@1|root,COG1493@2|Bacteria,1G5K9@1117|Cyanobacteria	1117|Cyanobacteria	T	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1654628_0	395961.Cyan7425_2952	8.209e-111	380.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria	1117|Cyanobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_1654628_3	868131.MSWAN_1379	8.976e-20	92.0	arCOG03838@1|root,arCOG03838@2157|Archaea,2Y1S5@28890|Euryarchaeota	28890|Euryarchaeota	H	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS2_k127_1654628_4	497964.CfE428DRAFT_4235	4.945e-10	61.0	COG0673@1|root,COG0673@2|Bacteria,46UK6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_1667125_1	204669.Acid345_3895	5.672e-65	245.0	COG1629@1|root,COG1629@2|Bacteria,3Y99A@57723|Acidobacteria,2JP5H@204432|Acidobacteriia	204432|Acidobacteriia	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1667125_0	1123276.KB893264_gene4598	1.652e-106	370.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_1673996_1	1340493.JNIF01000003_gene2836	6.671e-135	452.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria,3Y388@57723|Acidobacteria	57723|Acidobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
GDHHQS2_k127_1673996_2	234267.Acid_0749	1.435e-127	434.0	COG0476@1|root,COG0476@2|Bacteria,3Y2HZ@57723|Acidobacteria	57723|Acidobacteria	H	MoeZ MoeB domain	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
GDHHQS2_k127_1673996_0	1267535.KB906767_gene3597	4.28e-281	893.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
GDHHQS2_k127_1673996_3	1340493.JNIF01000003_gene3621	1.143e-23	109.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	nifM	-	2.3.1.39,5.2.1.8	ko:K00645,ko:K01802,ko:K02597,ko:K03769,ko:K03770,ko:K03771	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS2_k127_1686624_0	234267.Acid_1598	2.611e-124	405.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS2_k127_1686624_1	1210884.HG799465_gene12059	3.928e-29	121.0	28TQ4@1|root,2ZFXE@2|Bacteria,2J25I@203682|Planctomycetes	203682|Planctomycetes	S	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1688529_0	234267.Acid_6973	0.0	1079.0	COG1966@1|root,COG1966@2|Bacteria,3Y436@57723|Acidobacteria	57723|Acidobacteria	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
GDHHQS2_k127_1688529_1	1267535.KB906767_gene3824	8.412e-29	133.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_1696955_3	1340493.JNIF01000003_gene4787	9.467e-72	246.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_1696955_1	330214.NIDE0585	3.206e-138	487.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
GDHHQS2_k127_1696955_4	234267.Acid_7445	2.634e-67	241.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_1696955_0	234267.Acid_0426	5.138e-196	622.0	COG3829@1|root,COG3829@2|Bacteria,3Y988@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
GDHHQS2_k127_1696955_5	1267535.KB906767_gene516	5.759e-34	134.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	3.1.2.28	ko:K07107,ko:K12073	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS2_k127_1696955_2	402777.KB235903_gene1631	3.466e-87	293.0	COG2326@1|root,COG2326@2|Bacteria,1G34U@1117|Cyanobacteria,1H708@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GDHHQS2_k127_1696955_6	204669.Acid345_0263	1.177e-12	72.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_1702352_8	1340493.JNIF01000003_gene4599	9.832e-44	168.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_1702352_1	1340493.JNIF01000003_gene4597	3.287e-107	358.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_1702352_4	35754.JNYJ01000035_gene3986	8.874e-73	261.0	COG4948@1|root,COG4948@2|Bacteria,2H17U@201174|Actinobacteria,4DGXJ@85008|Micromonosporales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1702352_3	443598.AUFA01000022_gene3252	1.58e-94	323.0	COG2706@1|root,COG2706@2|Bacteria,1R9QR@1224|Proteobacteria,2U4RJ@28211|Alphaproteobacteria,3K346@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_1702352_6	886293.Sinac_5574	4.295e-55	205.0	COG1689@1|root,COG4099@1|root,COG1689@2|Bacteria,COG4099@2|Bacteria,2J4VN@203682|Planctomycetes	203682|Planctomycetes	S	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GDHHQS2_k127_1702352_5	661478.OP10G_4294	4.878e-60	214.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GDHHQS2_k127_1702352_7	745310.G432_16750	3.1e-44	168.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,2VFNR@28211|Alphaproteobacteria,2KCUH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1702352_10	240015.ACP_2628	3.564e-17	85.0	2DS95@1|root,33F2G@2|Bacteria,3Y5B4@57723|Acidobacteria,2JJRN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1702352_9	882378.RBRH_01830	1.047e-42	162.0	COG5378@1|root,COG5378@2|Bacteria,1PIIF@1224|Proteobacteria,2W75C@28216|Betaproteobacteria,1KDV4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_2
GDHHQS2_k127_1702352_0	234267.Acid_5940	5.448e-187	613.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_1702352_2	1123508.JH636442_gene4015	7.435e-95	324.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_1703448_1	240015.ACP_1354	8.925e-35	139.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1703448_2	179408.Osc7112_6220	1.606e-19	100.0	COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
GDHHQS2_k127_1703448_0	1267535.KB906767_gene4837	3.152e-69	250.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1713313_1	1267535.KB906767_gene4419	2.895e-167	530.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_1713313_2	1340493.JNIF01000003_gene2795	2.434e-115	379.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria	57723|Acidobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS2_k127_1713313_3	1297865.APJD01000033_gene6968	9.667e-73	253.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,3JT02@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS2_k127_1713313_6	1128421.JAGA01000001_gene2145	1.806e-38	147.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_05735	-	-	-	-	-	-	-	-	-	-	-	HTH_34
GDHHQS2_k127_1713313_5	861299.J421_1010	2.701e-56	202.0	COG3127@1|root,COG3127@2|Bacteria,1ZU3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1713313_0	1340493.JNIF01000003_gene4528	9.765e-286	888.0	COG0129@1|root,COG0129@2|Bacteria	2|Bacteria	EG	dihydroxy-acid dehydratase activity	ilvD1	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_1713313_4	234267.Acid_6234	4.522e-64	225.0	COG1682@1|root,COG1682@2|Bacteria,3Y8HI@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GDHHQS2_k127_171686_2	234267.Acid_0872	5.98e-62	238.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_171686_0	234267.Acid_5643	1.562e-169	539.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria	57723|Acidobacteria	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_171686_1	234267.Acid_0191	9.008e-72	258.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	phlE	-	-	ko:K02511,ko:K02575,ko:K13021	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.14.3,2.A.1.14.9,2.A.1.8	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_171686_4	1123242.JH636434_gene5501	7.526e-48	189.0	COG3836@1|root,COG3836@2|Bacteria,2IYIM@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_171686_5	338963.Pcar_1138	1.863e-47	185.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
GDHHQS2_k127_171686_3	1096930.L284_11990	1.554e-53	197.0	COG3291@1|root,COG3291@2|Bacteria,1QUTU@1224|Proteobacteria,2TW7C@28211|Alphaproteobacteria,2KECE@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_1717855_0	760192.Halhy_3819	1.513e-213	692.0	COG0308@1|root,COG0842@1|root,COG1277@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1IPQP@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS2_k127_1717855_3	1166018.FAES_5300	9.049e-132	426.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_1717855_1	234267.Acid_2483	7.696e-206	647.0	COG0172@1|root,COG0172@2|Bacteria,3Y2UD@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS2_k127_1717855_4	189753.AXAS01000013_gene5867	4.437e-108	362.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2TRQ1@28211|Alphaproteobacteria,3JSJF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
GDHHQS2_k127_1717855_2	880071.Fleli_0601	1.541e-147	490.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS2_k127_1722655_0	234267.Acid_4352	1.316e-123	403.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
GDHHQS2_k127_1722655_6	204669.Acid345_3489	1.427e-34	139.0	COG4758@1|root,COG4758@2|Bacteria,3Y554@57723|Acidobacteria,2JNA4@204432|Acidobacteriia	204432|Acidobacteriia	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
GDHHQS2_k127_1722655_3	204669.Acid345_3488	3.167e-65	246.0	COG2972@1|root,COG2972@2|Bacteria,3Y4BE@57723|Acidobacteria,2JMFY@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
GDHHQS2_k127_1722655_1	204669.Acid345_3487	2.276e-81	294.0	COG3279@1|root,COG3279@2|Bacteria,3Y3B3@57723|Acidobacteria,2JP1W@204432|Acidobacteriia	204432|Acidobacteriia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS2_k127_1722655_2	234267.Acid_7005	9.591e-81	302.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1722655_4	589924.Ferp_2404	2.897e-61	220.0	arCOG03850@1|root,arCOG03850@2157|Archaea,2XYUB@28890|Euryarchaeota	28890|Euryarchaeota	S	Cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GDHHQS2_k127_1722655_5	1340493.JNIF01000003_gene2645	4.214e-56	210.0	COG2312@1|root,COG2312@2|Bacteria,3Y8PV@57723|Acidobacteria	57723|Acidobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
GDHHQS2_k127_1730336_1	373994.Riv7116_4057	6.898e-08	63.0	COG5652@1|root,COG5652@2|Bacteria,1GC2R@1117|Cyanobacteria,1HM2P@1161|Nostocales	1117|Cyanobacteria	S	PFAM VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS2_k127_1730336_0	671143.DAMO_2345	4.343e-140	453.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	lspL	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_1735895_1	519989.ECTPHS_13917	9.831e-114	373.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,1RYEE@1236|Gammaproteobacteria,1X16K@135613|Chromatiales	135613|Chromatiales	V	Mrr N-terminal domain	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
GDHHQS2_k127_1735895_0	1443111.JASG01000004_gene421	1.065e-148	478.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3ZUWI@60136|Sulfitobacter	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_1746158_0	234267.Acid_6871	4.128e-154	498.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1746158_1	234267.Acid_1170	9.609e-103	341.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_1746158_2	1340493.JNIF01000004_gene606	4.898e-93	314.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_1746158_4	156889.Mmc1_2551	4.722e-10	64.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
GDHHQS2_k127_1746158_3	156889.Mmc1_2624	5.472e-17	87.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
GDHHQS2_k127_1746439_6	40571.JOEA01000004_gene6440	2.322e-23	106.0	COG0047@1|root,COG0047@2|Bacteria	2|Bacteria	F	phosphoribosylformylglycinamidine synthase activity	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
GDHHQS2_k127_1746439_0	40571.JOEA01000004_gene6441	1.771e-295	931.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
GDHHQS2_k127_1746439_2	234267.Acid_5735	1.102e-97	325.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_1746439_5	1267535.KB906767_gene1980	2.068e-26	113.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_37
GDHHQS2_k127_1746439_4	411684.HPDFL43_04590	5.548e-27	113.0	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,2UBYT@28211|Alphaproteobacteria,43PYG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_1746439_1	1340493.JNIF01000003_gene1861	3.589e-116	387.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_1746439_3	1340493.JNIF01000003_gene1861	1.267e-47	180.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_1750882_1	316067.Geob_0079	4.253e-38	145.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1750882_3	1500301.JQMF01000013_gene4468	5.174e-11	73.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,4B99V@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1750882_2	234267.Acid_5834	3.285e-28	120.0	COG0667@1|root,COG0667@2|Bacteria,3Y2TA@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1750882_0	1340493.JNIF01000003_gene2506	1.505e-281	884.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GDHHQS2_k127_1755549_0	1267535.KB906767_gene1536	4.399e-203	668.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1755549_1	358681.BBR47_52060	1.066e-115	394.0	COG1506@1|root,COG1506@2|Bacteria,1VSK9@1239|Firmicutes,4HU6U@91061|Bacilli,2727N@186822|Paenibacillaceae	91061|Bacilli	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_1755549_3	1196323.ALKF01000172_gene114	3.25e-55	197.0	COG1506@1|root,COG4188@1|root,COG1506@2|Bacteria,COG4188@2|Bacteria,1VSK9@1239|Firmicutes,4HU6U@91061|Bacilli,2727N@186822|Paenibacillaceae	91061|Bacilli	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_1755549_5	1267533.KB906739_gene2634	1.272e-16	87.0	28J2W@1|root,2Z8Z6@2|Bacteria,3Y2KF@57723|Acidobacteria,2JIUG@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1755549_2	1267535.KB906767_gene1480	4.727e-88	298.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_1755549_4	234267.Acid_1659	2.101e-24	104.0	COG1610@1|root,COG1610@2|Bacteria,3Y4VF@57723|Acidobacteria	57723|Acidobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS2_k127_1757644_1	1340493.JNIF01000003_gene2013	7.954e-49	179.0	COG1076@1|root,COG1076@2|Bacteria,3Y4MR@57723|Acidobacteria	57723|Acidobacteria	O	PFAM heat shock protein DnaJ	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
GDHHQS2_k127_1757644_0	1267535.KB906767_gene195	1.445e-289	900.0	COG0443@1|root,COG0443@2|Bacteria,3Y2F8@57723|Acidobacteria,2JIVF@204432|Acidobacteriia	204432|Acidobacteriia	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
GDHHQS2_k127_1757644_2	240015.ACP_2551	1.778e-26	112.0	COG2975@1|root,COG2975@2|Bacteria,3Y5I4@57723|Acidobacteria,2JJZY@204432|Acidobacteriia	204432|Acidobacteriia	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
GDHHQS2_k127_1759131_1	1340493.JNIF01000003_gene1646	2.541e-131	425.0	COG1894@1|root,COG1894@2|Bacteria,3Y2NM@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS2_k127_1759131_3	234267.Acid_0112	1.128e-79	269.0	COG1905@1|root,COG1905@2|Bacteria,3Y4SI@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS2_k127_1759131_0	234267.Acid_0111	7.448e-190	601.0	COG0649@1|root,COG0649@2|Bacteria,3Y3N1@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
GDHHQS2_k127_1759131_4	234267.Acid_0110	2.099e-59	210.0	COG0852@1|root,COG0852@2|Bacteria,3Y4IQ@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS2_k127_1759131_6	1267535.KB906767_gene4279	1.855e-43	165.0	COG0838@1|root,COG0838@2|Bacteria,3Y5CV@57723|Acidobacteria,2JP4J@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS2_k127_1759131_2	1249997.JHZW01000002_gene249	1.295e-85	292.0	COG1524@1|root,COG1524@2|Bacteria,4NIUS@976|Bacteroidetes,1HZKJ@117743|Flavobacteriia,2PHA1@252356|Maribacter	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
GDHHQS2_k127_1759131_5	1137799.GZ78_27220	5.835e-47	173.0	COG1443@1|root,COG1443@2|Bacteria,1P8AM@1224|Proteobacteria,1RQA3@1236|Gammaproteobacteria,1XM4C@135619|Oceanospirillales	135619|Oceanospirillales	I	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_1759131_7	234267.Acid_1907	2.386e-39	161.0	2FA03@1|root,34298@2|Bacteria,3Y84H@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1759131_8	1185876.BN8_06038	1.201e-26	119.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_176423_1	1267535.KB906767_gene1551	2.124e-111	367.0	COG0179@1|root,COG0179@2|Bacteria,3Y4QZ@57723|Acidobacteria,2JP1G@204432|Acidobacteriia	204432|Acidobacteriia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_176423_7	525904.Tter_0985	2.875e-33	133.0	COG1832@1|root,COG1832@2|Bacteria,2NRIH@2323|unclassified Bacteria	2|Bacteria	S	CoA binding domain	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS2_k127_176423_4	234267.Acid_6491	1.199e-96	321.0	COG1187@1|root,COG1187@2|Bacteria,3Y3CQ@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_176423_5	234267.Acid_6490	4.234e-77	267.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS2_k127_176423_3	1340493.JNIF01000004_gene492	2.761e-100	332.0	COG1354@1|root,COG1354@2|Bacteria,3Y458@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS2_k127_176423_2	234267.Acid_0127	4.34e-109	361.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
GDHHQS2_k127_176423_6	204669.Acid345_2659	1.102e-44	171.0	2BNC6@1|root,32GZV@2|Bacteria,3Y8TE@57723|Acidobacteria	57723|Acidobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
GDHHQS2_k127_176423_0	204669.Acid345_2658	7.929e-260	812.0	COG2303@1|root,COG2303@2|Bacteria,3Y41Y@57723|Acidobacteria,2JIXF@204432|Acidobacteriia	204432|Acidobacteriia	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_1764891_0	234267.Acid_7510	4.254e-174	571.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1768537_1	234267.Acid_4530	8.05e-33	128.0	2DB8U@1|root,2Z7SW@2|Bacteria,3Y3IM@57723|Acidobacteria	57723|Acidobacteria	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
GDHHQS2_k127_1768537_0	1340493.JNIF01000004_gene88	3.764e-197	644.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_1772221_0	1340493.JNIF01000003_gene2379	9.952e-247	782.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1772221_4	1340493.JNIF01000004_gene236	0.0009404	51.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16,TPR_4
GDHHQS2_k127_1772221_1	1267535.KB906767_gene936	1.343e-86	295.0	COG1269@1|root,COG1269@2|Bacteria,3Y62W@57723|Acidobacteria	57723|Acidobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
GDHHQS2_k127_1772221_2	1340493.JNIF01000003_gene2340	2.667e-64	227.0	COG1269@1|root,COG1269@2|Bacteria,3Y565@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
GDHHQS2_k127_1772221_3	234267.Acid_3470	1.627e-48	179.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1782892_1	234267.Acid_4945	1.027e-94	317.0	2B33H@1|root,31VR5@2|Bacteria,3Y819@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1782892_0	234267.Acid_6145	2.082e-195	618.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1782892_2	240016.ABIZ01000001_gene2703	7.962e-14	77.0	COG2010@1|root,COG5492@1|root,COG2010@2|Bacteria,COG5492@2|Bacteria,46SD1@74201|Verrucomicrobia,2IVJE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1783916_0	1168065.DOK_15609	1.374e-77	269.0	COG1404@1|root,COG3227@1|root,COG1404@2|Bacteria,COG3227@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1J50P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
GDHHQS2_k127_1783916_1	342113.DM82_3038	1.964e-29	129.0	COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria	1224|Proteobacteria	M	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS2_k127_1785857_2	234267.Acid_7690	9.358e-21	99.0	COG3712@1|root,COG3712@2|Bacteria,3Y772@57723|Acidobacteria	57723|Acidobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS2_k127_1785857_0	234267.Acid_7689	3.618e-125	410.0	COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_1785857_3	575540.Isop_2112	9.7e-10	69.0	COG1277@1|root,COG1277@2|Bacteria,2J0ZV@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GDHHQS2_k127_1785857_1	234267.Acid_7687	3.144e-59	209.0	COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_1791292_1	234267.Acid_0766	2.012e-98	326.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS2_k127_1791292_6	1121456.ATVA01000017_gene171	6.021e-05	54.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,2MDF1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
GDHHQS2_k127_1791292_2	234267.Acid_0761	8.535e-88	304.0	COG1587@1|root,COG1587@2|Bacteria,3Y7CM@57723|Acidobacteria	57723|Acidobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
GDHHQS2_k127_1791292_3	331869.BAL199_24289	2.655e-51	188.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VC8M@28211|Alphaproteobacteria,4BSKF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1791292_0	1340493.JNIF01000003_gene3635	1.277e-282	876.0	COG2303@1|root,COG2303@2|Bacteria,3Y6FS@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_1795781_2	1432050.IE4771_PA00016	2.292e-92	328.0	COG1403@1|root,COG3950@1|root,COG1403@2|Bacteria,COG3950@2|Bacteria,1MUE0@1224|Proteobacteria,2U5YT@28211|Alphaproteobacteria,4BF36@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
GDHHQS2_k127_1795781_3	448385.sce6429	3.965e-65	232.0	COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_1795781_0	1340493.JNIF01000003_gene3677	2.082e-192	610.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GDHHQS2_k127_1795781_1	234267.Acid_2256	1.42e-127	415.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1813526_10	396588.Tgr7_1594	1.191e-65	225.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_1813526_2	1340493.JNIF01000003_gene2841	9.257e-235	752.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_1813526_12	187303.BN69_0062	8.695e-48	178.0	COG5573@1|root,COG5573@2|Bacteria,1N9U9@1224|Proteobacteria,2VEQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_1813526_9	234267.Acid_5289	1.639e-101	334.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria	57723|Acidobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS2_k127_1813526_5	234267.Acid_0484	1.058e-165	531.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_1813526_11	234267.Acid_0483	8.149e-52	192.0	COG0509@1|root,COG0509@2|Bacteria,3Y55C@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS2_k127_1813526_3	234267.Acid_0482	1.314e-201	638.0	COG0403@1|root,COG0403@2|Bacteria,3Y2WZ@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GDHHQS2_k127_1813526_1	234267.Acid_0481	4.237e-262	813.0	COG1003@1|root,COG1003@2|Bacteria,3Y2UZ@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GDHHQS2_k127_1813526_6	234267.Acid_0480	5.296e-157	514.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_1813526_0	234267.Acid_4027	2.613e-267	866.0	COG1629@1|root,COG4771@2|Bacteria,3Y6QJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1813526_7	1000565.METUNv1_01393	6.785e-128	419.0	COG2159@1|root,COG2159@2|Bacteria,1PZ2U@1224|Proteobacteria,2W9HT@28216|Betaproteobacteria,2KZNG@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_1813526_4	234267.Acid_3564	2.821e-174	559.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria,3Y3PB@57723|Acidobacteria	57723|Acidobacteria	Q	FAD dependent oxidoreductase	-	-	1.3.5.6	ko:K00514	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04798,R04800,R07511,R09656,R09658	RC01214,RC01959	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS2_k127_1813526_14	529818.AMSG_06255T0	0.0007529	46.0	2CCHR@1|root,2SX87@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1813526_8	1340493.JNIF01000003_gene2171	1.793e-125	406.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,3Y2UX@57723|Acidobacteria	57723|Acidobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K13503,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
GDHHQS2_k127_1816221_0	580340.Tlie_0809	1.477e-117	389.0	COG0162@1|root,COG0162@2|Bacteria,3T9YV@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS2_k127_1816221_3	1267535.KB906767_gene2831	0.0001393	54.0	2FHPT@1|root,349HD@2|Bacteria,3Y8EI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1816221_1	234267.Acid_0458	9.977e-55	200.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_1816221_2	234267.Acid_0060	2.973e-37	148.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS2_k127_1817282_2	1382306.JNIM01000001_gene853	5.169e-21	93.0	COG1304@1|root,COG1304@2|Bacteria,2G84G@200795|Chloroflexi	200795|Chloroflexi	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
GDHHQS2_k127_1817282_0	234267.Acid_3819	6.097e-116	398.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1817282_1	1340493.JNIF01000003_gene1756	2.014e-53	198.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_1820909_3	340177.Cag_1600	1.059e-43	165.0	COG3950@1|root,COG3950@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
GDHHQS2_k127_1820909_2	340177.Cag_1599	1.441e-49	184.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GDHHQS2_k127_1820909_1	1210884.HG799469_gene14163	6.484e-122	408.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_1820909_4	903818.KI912268_gene2972	7.73e-28	119.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DoxX,Sulfatase
GDHHQS2_k127_1820909_0	234267.Acid_7573	2.282e-275	885.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1834491_7	1340493.JNIF01000003_gene2637	1.192e-47	176.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,TonB_C
GDHHQS2_k127_1834491_3	234267.Acid_0066	3.541e-95	321.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS2_k127_1834491_2	234267.Acid_7164	7.975e-151	513.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Beta_helix,CBM_6,F5_F8_type_C,Hepar_II_III,Hepar_II_III_N
GDHHQS2_k127_1834491_6	744872.Spica_0095	5.184e-82	287.0	COG1373@1|root,COG1373@2|Bacteria,2J5MK@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_1834491_0	1340493.JNIF01000003_gene3050	2.918e-179	579.0	COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria	57723|Acidobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS2_k127_1834491_9	641526.ADIWIN_1972	5.778e-44	177.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_1834491_5	1340493.JNIF01000003_gene3051	6.971e-83	280.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS2_k127_1834491_10	1267535.KB906767_gene575	3.404e-31	130.0	COG0848@1|root,COG0848@2|Bacteria,3Y4QV@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_1834491_8	1340493.JNIF01000003_gene3053	2.618e-44	170.0	COG0810@1|root,COG0810@2|Bacteria,3Y4WH@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
GDHHQS2_k127_1834491_1	1340493.JNIF01000003_gene3054	1.719e-154	501.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_1834491_4	234267.Acid_0513	2.459e-83	284.0	COG2885@1|root,COG2885@2|Bacteria,3Y3ZY@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS2_k127_1835284_2	234267.Acid_7208	5.243e-12	72.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1835284_1	234267.Acid_7209	5.126e-58	203.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_1835284_0	1120919.AUBI01000027_gene3516	5.298e-217	682.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,2JWFT@204441|Rhodospirillales	204441|Rhodospirillales	Q	Retinal pigment epithelial membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	RPE65
GDHHQS2_k127_1837773_0	497964.CfE428DRAFT_0108	2.396e-20	106.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1851736_0	1379270.AUXF01000007_gene1018	1.839e-263	835.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,1ZUBH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_1851736_1	390874.Tpet_1352	6.305e-07	55.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_185860_3	344747.PM8797T_11626	5.044e-11	64.0	2EZBQ@1|root,33SH2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_185860_1	388413.ALPR1_06685	1.887e-68	246.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,47KYS@768503|Cytophagia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
GDHHQS2_k127_185860_2	1254432.SCE1572_23875	1.131e-46	177.0	COG0454@1|root,COG0456@2|Bacteria,1NCW1@1224|Proteobacteria,42XYS@68525|delta/epsilon subdivisions,2WT5Q@28221|Deltaproteobacteria,2Z06J@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
GDHHQS2_k127_185860_0	234267.Acid_0024	1.055e-96	340.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_1859628_6	234267.Acid_2975	1.866e-12	68.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1859628_4	1123073.KB899245_gene23	4.166e-34	153.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_1859628_7	391612.CY0110_13938	2.264e-08	59.0	COG4679@1|root,COG4679@2|Bacteria,1G6SB@1117|Cyanobacteria	1117|Cyanobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_1859628_1	234267.Acid_0899	9.747e-134	440.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	2|Bacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
GDHHQS2_k127_1859628_3	234267.Acid_0898	1.334e-50	182.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS2_k127_1859628_5	278963.ATWD01000001_gene2540	4.083e-20	102.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_1859628_8	1500257.JQNM01000011_gene5582	2.294e-06	56.0	COG2186@1|root,COG2186@2|Bacteria,1R68P@1224|Proteobacteria,2U9AP@28211|Alphaproteobacteria,4BCE2@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_1859628_9	756272.Plabr_4629	7.47e-05	47.0	COG2186@1|root,COG2186@2|Bacteria,2J3Y3@203682|Planctomycetes	203682|Planctomycetes	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_1859628_11	886293.Sinac_6741	0.0002263	49.0	COG2010@1|root,COG2010@2|Bacteria,2J2AZ@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1859628_2	1267534.KB906759_gene1736	1.273e-91	318.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1859628_0	1340493.JNIF01000003_gene2320	5.99e-217	705.0	COG1629@1|root,COG4771@2|Bacteria	1340493.JNIF01000003_gene2320|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1859628_10	234267.Acid_1389	0.0001682	46.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1865652_2	234267.Acid_3175	3.234e-59	219.0	COG1075@1|root,COG1404@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,3Y2EZ@57723|Acidobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GDHHQS2_k127_1865652_0	234267.Acid_7676	5.207e-134	441.0	COG2234@1|root,COG2234@2|Bacteria,3Y43U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_1865652_1	1340493.JNIF01000003_gene3944	1.963e-125	424.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GDHHQS2_k127_1865652_5	316056.RPC_2215	0.0009772	47.0	COG3609@1|root,COG3609@2|Bacteria,1NGY5@1224|Proteobacteria,2UJG0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
GDHHQS2_k127_1865652_3	671143.DAMO_3050	5.622e-08	61.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS2_k127_1874612_0	497964.CfE428DRAFT_3521	1.357e-104	352.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1874612_1	926550.CLDAP_09410	0.0004087	50.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2G80F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GDHHQS2_k127_1883339_4	1469557.JSWF01000018_gene66	4.64e-12	79.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_1883339_1	234267.Acid_1894	2.923e-91	327.0	COG2312@1|root,COG2312@2|Bacteria,3Y8PV@57723|Acidobacteria	57723|Acidobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
GDHHQS2_k127_1883339_0	243090.RB4667	3.2e-136	446.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1883339_2	215803.DB30_2889	7.708e-68	233.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,43A1M@68525|delta/epsilon subdivisions,2X25R@28221|Deltaproteobacteria,2YUPF@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_1887390_2	485918.Cpin_6463	2.185e-50	188.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,1IQ4Q@117747|Sphingobacteriia	976|Bacteroidetes	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_1887390_0	1267535.KB906767_gene310	2.836e-101	348.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_1887390_1	485918.Cpin_6462	3.952e-67	246.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_1888893_3	1340493.JNIF01000004_gene887	1.656e-14	77.0	COG1506@1|root,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_1888893_0	1267535.KB906767_gene1686	3.144e-153	495.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_1888893_2	111780.Sta7437_2870	1.262e-14	81.0	2A82V@1|root,30X3B@2|Bacteria,1GBA8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1888893_1	1028800.RG540_PA15200	3.655e-36	141.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,4BBEI@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1902426_1	234267.Acid_1598	7.169e-61	214.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS2_k127_1902426_0	234267.Acid_2377	1.275e-141	452.0	COG0388@1|root,COG0388@2|Bacteria,3Y7FJ@57723|Acidobacteria	57723|Acidobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_1902426_2	555779.Dthio_PD3203	3.223e-13	70.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42UHK@68525|delta/epsilon subdivisions,2WQDH@28221|Deltaproteobacteria,2MG0C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS2_k127_1903871_0	1123242.JH636435_gene2738	4.971e-189	601.0	COG3119@1|root,COG3119@2|Bacteria,2IWZ2@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1903871_3	1232410.KI421412_gene337	5.736e-09	60.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS2_k127_1903871_2	1232410.KI421412_gene336	2.124e-17	83.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1903871_1	234267.Acid_2862	3.317e-87	293.0	COG0577@1|root,COG0577@2|Bacteria,3Y3ZQ@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1903937_1	1038867.AXAY01000008_gene557	1.546e-23	110.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2U12A@28211|Alphaproteobacteria,3JXJP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Trans_reg_C
GDHHQS2_k127_1903937_0	234267.Acid_3357	3.622e-60	211.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_1909990_3	234267.Acid_7635	2.286e-18	99.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,Amidase_6,GHL10,fn3
GDHHQS2_k127_1909990_5	32057.KB217478_gene2465	3.705e-08	60.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
GDHHQS2_k127_1909990_4	166314.Syncc8109_0589	8.793e-16	80.0	2DWFK@1|root,3403Z@2|Bacteria,1GNBR@1117|Cyanobacteria,1H0Q3@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
GDHHQS2_k127_1909990_2	1267533.KB906737_gene1923	9.647e-51	188.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
GDHHQS2_k127_1909990_0	234267.Acid_7403	1.031e-124	403.0	COG0479@1|root,COG0479@2|Bacteria,3Y3XR@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
GDHHQS2_k127_1909990_1	1382359.JIAL01000001_gene2876	2.192e-76	259.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria,2JIC4@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_1913607_2	639030.JHVA01000001_gene815	1.295e-158	516.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1913607_0	234267.Acid_6854	3.224e-260	842.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1913607_5	234267.Acid_4576	1.784e-62	223.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_1913607_1	234267.Acid_4577	1.737e-241	755.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_1913607_4	234267.Acid_0985	1.484e-63	224.0	COG0652@1|root,COG0652@2|Bacteria,3Y7R6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS2_k127_1913607_3	1267535.KB906767_gene2406	2.203e-134	432.0	COG1082@1|root,COG1082@2|Bacteria,3Y2PT@57723|Acidobacteria,2JI9Z@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_1913607_7	234267.Acid_2219	5.898e-23	101.0	COG0784@1|root,COG0784@2|Bacteria,3Y4W5@57723|Acidobacteria	57723|Acidobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_1913866_1	886293.Sinac_2820	5.759e-33	145.0	28HBM@1|root,2Z7NK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1913866_0	143224.JQMD01000002_gene128	1.605e-111	377.0	28HBM@1|root,2Z7NK@2|Bacteria,4NKA6@976|Bacteroidetes,1I8IP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1913866_2	1121904.ARBP01000021_gene3579	7.018e-06	51.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1919304_3	386456.JQKN01000003_gene359	2.27e-17	85.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,23PIB@183925|Methanobacteria	183925|Methanobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_1919304_4	298654.FraEuI1c_6924	2.681e-11	72.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4EWI4@85013|Frankiales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
GDHHQS2_k127_1919304_2	1090319.KE386571_gene329	5.961e-49	180.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS2_k127_1919304_1	1125863.JAFN01000001_gene2299	6.844e-57	206.0	COG2344@1|root,COG2344@2|Bacteria,1R55V@1224|Proteobacteria,42M2S@68525|delta/epsilon subdivisions,2WM6N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS2_k127_1919304_0	1242864.D187_000308	4.469e-127	419.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS2_k127_1919307_4	1121875.KB907546_gene2689	2.53e-20	93.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
GDHHQS2_k127_1919307_3	1170562.Cal6303_2768	9.764e-28	117.0	COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_1919307_0	498761.HM1_1611	1.394e-128	438.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_1919307_5	1267535.KB906767_gene3903	1.39e-12	76.0	2E1AY@1|root,32WQW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1919307_1	404589.Anae109_4231	1.475e-44	168.0	arCOG07238@1|root,34BTI@2|Bacteria,1P13S@1224|Proteobacteria,4354M@68525|delta/epsilon subdivisions,2WZFN@28221|Deltaproteobacteria,2Z21A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1919307_2	926560.KE387023_gene1476	4.093e-43	161.0	COG3383@1|root,COG3383@2|Bacteria,1WJDD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS2_k127_1920539_2	1267535.KB906767_gene3695	1.962e-139	476.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1920539_6	1267535.KB906767_gene3529	6.269e-41	158.0	COG1695@1|root,COG1695@2|Bacteria,3Y80F@57723|Acidobacteria,2JMYK@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_1920539_0	1340493.JNIF01000004_gene889	1.008e-234	733.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1920539_1	1340493.JNIF01000004_gene890	5.651e-231	735.0	COG2010@1|root,COG3695@1|root,COG2010@2|Bacteria,COG3695@2|Bacteria,3Y5FU@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
GDHHQS2_k127_1920539_3	1267535.KB906767_gene5492	3.556e-125	411.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_1920539_4	1267535.KB906767_gene3536	3.262e-81	276.0	COG0283@1|root,COG0283@2|Bacteria,3Y4MV@57723|Acidobacteria,2JJ7N@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS2_k127_1920539_5	1340493.JNIF01000004_gene345	5.332e-64	226.0	COG0527@1|root,COG0527@2|Bacteria	2|Bacteria	E	aspartate kinase activity	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
GDHHQS2_k127_1930250_7	631362.Thi970DRAFT_01527	6.569e-08	55.0	COG3742@1|root,COG3742@2|Bacteria,1Q9VA@1224|Proteobacteria,1SS82@1236|Gammaproteobacteria,1X1GS@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1930250_9	1229172.JQFA01000004_gene429	2.048e-06	56.0	COG4423@1|root,COG4423@2|Bacteria,1GADN@1117|Cyanobacteria,1HG1G@1150|Oscillatoriales	1117|Cyanobacteria	S	Rv0623-like transcription factor	-	-	-	-	-	-	-	-	-	-	-	-	PSK_trans_fac
GDHHQS2_k127_1930250_0	639030.JHVA01000001_gene1886	1.074e-227	742.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_1930250_6	744980.TRICHSKD4_2948	5.611e-16	86.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Membrane	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS2_k127_1930250_2	1463855.JOHV01000007_gene5070	9.652e-59	225.0	COG2133@1|root,COG2133@2|Bacteria,2IB3Z@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1930250_4	1173028.ANKO01000197_gene6087	1.593e-26	117.0	COG0454@1|root,COG0456@2|Bacteria,1GEIS@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1930250_1	1267533.KB906736_gene903	3.955e-60	209.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_1930250_3	401053.AciPR4_3923	6.98e-35	136.0	COG1695@1|root,COG1695@2|Bacteria,3Y5BK@57723|Acidobacteria,2JJRQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_1930250_5	234267.Acid_2307	2.575e-25	111.0	COG0577@1|root,COG0577@2|Bacteria,3Y6XU@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1930250_8	234267.Acid_1737	1.401e-07	57.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1932671_1	234267.Acid_1491	6.707e-134	436.0	COG1215@1|root,COG1215@2|Bacteria,3Y2WN@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family group 2	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
GDHHQS2_k127_1932671_0	1340493.JNIF01000003_gene3527	3.135e-311	963.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS2_k127_193364_0	251229.Chro_4813	1.098e-194	622.0	COG1749@1|root,COG1749@2|Bacteria,1GBDW@1117|Cyanobacteria	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
GDHHQS2_k127_193364_1	485913.Krac_2632	3.046e-66	241.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
GDHHQS2_k127_193364_2	1219045.BV98_000046	2.147e-28	116.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,2K4NC@204457|Sphingomonadales	204457|Sphingomonadales	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_1937014_2	234267.Acid_6362	2.313e-91	312.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,SH3_3
GDHHQS2_k127_1937014_3	234267.Acid_6361	3.572e-32	130.0	COG4818@1|root,COG4818@2|Bacteria,3Y5MZ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,zinc_ribbon_2
GDHHQS2_k127_1937014_1	234267.Acid_3557	1.245e-109	364.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_1937014_0	234267.Acid_2049	4.969e-130	429.0	COG2010@1|root,COG3828@1|root,COG2010@2|Bacteria,COG3828@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1937014_5	216596.pRL80022	9.192e-12	78.0	COG1073@1|root,COG1073@2|Bacteria,1QUD5@1224|Proteobacteria,2TX8A@28211|Alphaproteobacteria,4BNUB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS2_k127_1937014_4	1968.JOEV01000002_gene7043	3.17e-24	118.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_1938958_3	1210884.HG799475_gene15229	2.129e-79	277.0	COG3119@1|root,COG3119@2|Bacteria,2IYGF@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1938958_1	595460.RRSWK_00625	1.145e-158	514.0	COG3119@1|root,COG3119@2|Bacteria,2J1X7@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_1938958_4	1210884.HG799462_gene8446	5.325e-79	273.0	COG0730@1|root,COG0730@2|Bacteria,2IZGZ@203682|Planctomycetes	203682|Planctomycetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_1938958_0	1123248.KB893325_gene1154	8.732e-190	610.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_1938958_9	1340493.JNIF01000004_gene436	2.06e-39	153.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	psbV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02720	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	iJN678.psbV	Cytochrom_C,Cytochrom_C550,Cytochrom_CIII,Cytochrome_C7
GDHHQS2_k127_1938958_6	234267.Acid_1599	1.106e-64	228.0	COG0793@1|root,COG0793@2|Bacteria,3Y6R0@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_1938958_5	1267535.KB906767_gene2254	2.102e-71	248.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS2_k127_1938958_7	234267.Acid_3194	4.844e-64	223.0	COG1666@1|root,COG1666@2|Bacteria,3Y4I3@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS2_k127_1938958_8	234267.Acid_3193	1.809e-51	187.0	COG2199@1|root,COG3706@2|Bacteria,3Y5QC@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_1938958_2	1340493.JNIF01000003_gene1323	1.814e-79	273.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
GDHHQS2_k127_1945666_1	1267533.KB906745_gene68	1.293e-61	216.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	2|Bacteria	Q	pfam abc	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS2_k127_1945666_0	1267533.KB906745_gene69	2.146e-81	282.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	pqiB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS2_k127_1945666_2	1267533.KB906745_gene70	5.24e-33	138.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
GDHHQS2_k127_1946946_0	234267.Acid_6258	3.2e-126	422.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	DUF3367,PMT_2
GDHHQS2_k127_1946946_1	1267535.KB906767_gene903	3.338e-103	346.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA2	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_194886_2	886293.Sinac_1739	5.913e-48	181.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_194886_0	595460.RRSWK_00767	2.194e-208	656.0	COG3119@1|root,COG3119@2|Bacteria,2IX9P@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_194886_1	234267.Acid_4413	8.875e-91	303.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GDHHQS2_k127_1956147_1	1340493.JNIF01000003_gene1755	2.751e-174	554.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1956147_0	1340493.JNIF01000003_gene2870	3.23e-228	718.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3Y3QY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS2_k127_1956147_2	234267.Acid_6602	2.209e-163	528.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,3Y2QH@57723|Acidobacteria	57723|Acidobacteria	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
GDHHQS2_k127_1961131_1	234267.Acid_4108	4.962e-172	550.0	COG1783@1|root,COG1783@2|Bacteria,3Y64R@57723|Acidobacteria	57723|Acidobacteria	S	phage Terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_0	1267535.KB906767_gene2464	1.222e-177	567.0	2BQIP@1|root,32JEF@2|Bacteria,3Y6MF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_4	234267.Acid_4110	8.932e-52	189.0	2F354@1|root,33VZU@2|Bacteria,3Y7X0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_2	1267535.KB906767_gene2466	5.506e-147	470.0	2BKJ2@1|root,32F0A@2|Bacteria,3Y70Q@57723|Acidobacteria	57723|Acidobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
GDHHQS2_k127_1961131_8	234267.Acid_4112	1.575e-11	70.0	2CB8U@1|root,2ZFXN@2|Bacteria,3Y96M@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_6	234267.Acid_4113	1.371e-33	139.0	2CB8V@1|root,342T5@2|Bacteria,3Y892@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_5	234267.Acid_4114	6.448e-34	138.0	2CDPF@1|root,349CP@2|Bacteria,3Y8RA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_3	234267.Acid_4115	2.524e-116	386.0	2EVZF@1|root,33PCY@2|Bacteria,3Y6QQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961131_7	234267.Acid_4116	3.099e-22	102.0	299A7@1|root,2ZWDD@2|Bacteria,3Y8TK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1965355_0	1267535.KB906767_gene2638	0.0	1320.0	COG2609@1|root,COG2609@2|Bacteria,3Y2M3@57723|Acidobacteria,2JHM5@204432|Acidobacteriia	204432|Acidobacteriia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS2_k127_1965355_7	1267535.KB906767_gene32	4.648e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1965355_6	517418.Ctha_1807	1.537e-37	152.0	COG1864@1|root,COG1864@2|Bacteria,1FFIK@1090|Chlorobi	1090|Chlorobi	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_1965355_8	511051.CSE_08040	0.0001254	46.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
GDHHQS2_k127_1965355_4	376686.Fjoh_0500	4.612e-119	398.0	COG1680@1|root,COG2976@1|root,COG1680@2|Bacteria,COG2976@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
GDHHQS2_k127_1965355_1	1340493.JNIF01000003_gene4575	4.148e-172	567.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_1965355_2	1123508.JH636442_gene4053	1.818e-152	494.0	COG4102@1|root,COG4102@2|Bacteria,2IYDS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1965355_3	1304877.KI519399_gene3045	7.455e-127	417.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JW29@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_06335	-	4.2.1.156,4.2.1.42,5.1.2.2	ko:K01781,ko:K20023	ko00053,ko00627,ko01120,map00053,map00627,map01120	-	R03791,R04161,R05608	RC00543,RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_1965355_5	1444711.CCJF01000005_gene1582	1.034e-60	216.0	COG3177@1|root,COG3177@2|Bacteria,2JGT6@204428|Chlamydiae	204428|Chlamydiae	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
GDHHQS2_k127_1965501_0	1340493.JNIF01000003_gene3565	9.712e-234	739.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1968216_4	580331.Thit_2250	0.0001879	47.0	COG5573@1|root,COG5573@2|Bacteria,1V7GS@1239|Firmicutes,24JFR@186801|Clostridia,42GMN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_1968216_1	234267.Acid_7393	8.439e-17	85.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_1968216_2	1449063.JMLS01000024_gene3701	6.52e-16	88.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,26TD9@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_1968216_3	713587.THITH_05625	4.886e-06	48.0	COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,1SA5B@1236|Gammaproteobacteria,1X13C@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS2_k127_1968216_5	713587.THITH_05620	0.0009664	49.0	COG4691@1|root,COG4691@2|Bacteria,1QN0P@1224|Proteobacteria,1TKCE@1236|Gammaproteobacteria,1X1US@135613|Chromatiales	135613|Chromatiales	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
GDHHQS2_k127_1968216_0	211114.JOEF01000008_gene1255	4.519e-38	152.0	COG0715@1|root,COG0715@2|Bacteria,2GNMC@201174|Actinobacteria,4E006@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_196895_1	1340493.JNIF01000003_gene4762	2.724e-115	376.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
GDHHQS2_k127_196895_0	344747.PM8797T_15706	3.942e-131	434.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_1969143_6	1210884.HG799463_gene10078	7.709e-11	66.0	COG1228@1|root,COG1228@2|Bacteria,2J1M0@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1969143_4	46234.ANA_C12252	1.31e-18	86.0	COG4680@1|root,COG4680@2|Bacteria,1GJX8@1117|Cyanobacteria,1HSSS@1161|Nostocales	1117|Cyanobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
GDHHQS2_k127_1969143_3	99598.Cal7507_2858	5.095e-23	103.0	COG5499@1|root,COG5499@2|Bacteria,1G6YN@1117|Cyanobacteria,1HNWU@1161|Nostocales	1117|Cyanobacteria	K	COGs COG5499 transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
GDHHQS2_k127_1969143_0	1122605.KB893637_gene3258	2.409e-117	391.0	COG0673@1|root,COG0673@2|Bacteria,4NN43@976|Bacteroidetes	976|Bacteroidetes	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1969143_5	1170562.Cal6303_0361	2.807e-13	77.0	2B9MH@1|root,322ZT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1969143_1	158822.LH89_08875	5.997e-106	369.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_1969143_2	1157637.KB892093_gene6796	5.785e-60	226.0	COG1633@1|root,COG1633@2|Bacteria,2I2TU@201174|Actinobacteria	201174|Actinobacteria	S	Ferritin-like	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin-like
GDHHQS2_k127_1969143_8	420662.Mpe_A0939	0.0001322	50.0	COG3832@1|root,COG3832@2|Bacteria,1REDB@1224|Proteobacteria,2VXCY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
GDHHQS2_k127_1969143_7	65093.PCC7418_3206	2.301e-10	62.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2442 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_197789_9	234267.Acid_0976	1.61e-53	196.0	2CNUX@1|root,32SHU@2|Bacteria,3Y87T@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF2760)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2760
GDHHQS2_k127_197789_1	234267.Acid_0977	9.342e-270	841.0	COG0443@1|root,COG0443@2|Bacteria,3Y661@57723|Acidobacteria	57723|Acidobacteria	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
GDHHQS2_k127_197789_0	234267.Acid_0981	0.0	1199.0	COG0443@1|root,COG0443@2|Bacteria,3Y7FW@57723|Acidobacteria	57723|Acidobacteria	O	DNA-K related protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
GDHHQS2_k127_197789_8	234267.Acid_0821	5.069e-96	331.0	COG0611@1|root,COG0611@2|Bacteria,3Y30U@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_197789_7	1267535.KB906767_gene2591	2.609e-110	377.0	COG4106@1|root,COG4106@2|Bacteria,3Y6KU@57723|Acidobacteria	57723|Acidobacteria	S	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS2_k127_197789_4	1499967.BAYZ01000173_gene5799	2.332e-141	453.0	COG1879@1|root,COG1879@2|Bacteria,2NQCX@2323|unclassified Bacteria	2|Bacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
GDHHQS2_k127_197789_6	1499967.BAYZ01000173_gene5798	3.603e-111	369.0	COG1172@1|root,COG1172@2|Bacteria,2NPUE@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_197789_2	1499967.BAYZ01000173_gene5797	3.862e-176	565.0	COG1129@1|root,COG1129@2|Bacteria,2NPR8@2323|unclassified Bacteria	2|Bacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	iLJ478.TM0956	ABC_tran
GDHHQS2_k127_197789_3	234267.Acid_5375	2.863e-142	466.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_197789_11	1047013.AQSP01000114_gene699	2.823e-26	110.0	COG3549@1|root,COG3549@2|Bacteria,2NRMI@2323|unclassified Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS2_k127_197789_12	1121440.AUMA01000016_gene182	3.966e-26	111.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria,2MD69@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS2_k127_197789_10	234267.Acid_2433	1.666e-33	134.0	COG0792@1|root,COG0792@2|Bacteria,3Y56J@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GDHHQS2_k127_197789_5	1340493.JNIF01000003_gene4346	1.177e-123	400.0	COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria	57723|Acidobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
GDHHQS2_k127_1977950_3	1408419.JHYG01000015_gene2550	1.862e-47	181.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
GDHHQS2_k127_1977950_4	234267.Acid_2988	2.778e-13	72.0	COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	57723|Acidobacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS2_k127_1977950_1	1267534.KB906754_gene3106	2.078e-64	245.0	COG1228@1|root,COG1228@2|Bacteria,3Y539@57723|Acidobacteria,2JKT2@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1977950_0	234267.Acid_0956	2.941e-72	251.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS2_k127_1977950_5	204669.Acid345_4391	4.471e-07	51.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_1977950_2	1340493.JNIF01000003_gene3464	8.012e-55	204.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_1978167_2	234267.Acid_7145	7.81e-121	396.0	COG2204@1|root,COG2204@2|Bacteria,3Y6BK@57723|Acidobacteria	57723|Acidobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
GDHHQS2_k127_1978167_0	1340493.JNIF01000003_gene3342	1.575e-193	618.0	COG1351@1|root,COG1351@2|Bacteria,3Y3AY@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
GDHHQS2_k127_1978167_8	1267535.KB906767_gene2935	2.203e-64	222.0	COG0756@1|root,COG0756@2|Bacteria,3Y58S@57723|Acidobacteria	57723|Acidobacteria	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
GDHHQS2_k127_1978167_6	1340493.JNIF01000003_gene2259	5.845e-97	322.0	COG2230@1|root,COG2230@2|Bacteria,3Y9AA@57723|Acidobacteria	57723|Acidobacteria	M	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_1978167_4	1267535.KB906767_gene3324	1.473e-114	380.0	COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS2_k127_1978167_10	1340493.JNIF01000003_gene2257	1.064e-24	109.0	COG1826@1|root,COG1826@2|Bacteria,3Y5TY@57723|Acidobacteria	57723|Acidobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS2_k127_1978167_13	234267.Acid_6461	0.0002311	48.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_1978167_7	518766.Rmar_2853	2.125e-67	260.0	COG0210@1|root,COG0841@1|root,COG0210@2|Bacteria,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1978167_5	1340493.JNIF01000004_gene606	3.143e-104	348.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_1978167_3	344747.PM8797T_18384	5.348e-120	397.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1978167_11	234267.Acid_7510	4.918e-11	65.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1978167_14	1340493.JNIF01000003_gene3011	0.0003596	49.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1978167_1	1267535.KB906767_gene1639	1.693e-149	513.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_1978167_9	1123073.KB899245_gene23	5.649e-54	213.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_1982141_0	1396418.BATQ01000046_gene6146	1.743e-149	481.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_1982141_2	143224.JQMD01000002_gene2475	1.61e-145	475.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_1982141_4	886293.Sinac_4679	3.323e-127	422.0	2DBKQ@1|root,2Z9U7@2|Bacteria,2IWVD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1982141_6	575590.HMPREF0156_01395	2.73e-37	153.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes	976|Bacteroidetes	F	DNA RNA non-specific endonuclease	nucA_1	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_1982141_1	575540.Isop_1913	3.737e-149	485.0	COG1409@1|root,COG1409@2|Bacteria,2IYSB@203682|Planctomycetes	203682|Planctomycetes	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
GDHHQS2_k127_1982141_8	324602.Caur_1849	8.775e-05	46.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
GDHHQS2_k127_1982141_7	234267.Acid_6695	3.807e-24	107.0	COG0745@1|root,COG0745@2|Bacteria,3Y933@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_1982141_3	234267.Acid_6692	5.792e-144	476.0	COG4191@1|root,COG4191@2|Bacteria,3Y4SZ@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
GDHHQS2_k127_1982141_5	234267.Acid_0053	1.073e-114	386.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria	57723|Acidobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS2_k127_1997314_0	1123508.JH636439_gene1122	1.102e-158	512.0	COG4102@1|root,COG4102@2|Bacteria,2IY0N@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_1997314_1	1123242.JH636434_gene5284	1.572e-142	480.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,2J2CG@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2008053_4	756272.Plabr_0535	3.289e-46	177.0	COG0657@1|root,COG0657@2|Bacteria,2IZ89@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH
GDHHQS2_k127_2008053_0	42256.RradSPS_2794	2.892e-142	464.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_2008053_3	1396418.BATQ01000020_gene5042	1.612e-105	351.0	28IED@1|root,2Z8GE@2|Bacteria,46VP7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
GDHHQS2_k127_2008053_1	1340493.JNIF01000003_gene4569	1.393e-123	411.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_2008053_2	1434325.AZQN01000002_gene1153	1.171e-113	385.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,47T92@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2008053_5	234267.Acid_5754	3.406e-40	152.0	COG3324@1|root,COG3324@2|Bacteria,3Y8A9@57723|Acidobacteria	57723|Acidobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_2008053_6	234267.Acid_0932	0.0001541	48.0	COG1629@1|root,COG4771@2|Bacteria,3Y6X7@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2022528_5	1502851.FG93_05995	8.938e-59	216.0	COG1171@1|root,COG1171@2|Bacteria,1QVNS@1224|Proteobacteria,2TUHW@28211|Alphaproteobacteria,3K6FK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Diaminopropionate ammonia-lyase	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
GDHHQS2_k127_2022528_3	1123242.JH636434_gene3281	1.252e-90	305.0	COG1024@1|root,COG1024@2|Bacteria,2IZFF@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GDHHQS2_k127_2022528_4	234267.Acid_0540	6.154e-76	263.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS2_k127_2022528_7	313606.M23134_02638	4.957e-07	57.0	2EIBB@1|root,33C2R@2|Bacteria,4NYRT@976|Bacteroidetes,47SNM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2022528_2	1340493.JNIF01000003_gene4320	2.754e-93	313.0	COG1321@1|root,COG1321@2|Bacteria,3Y5SN@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS2_k127_2022528_0	234267.Acid_3552	9.291e-189	604.0	COG2234@1|root,COG2234@2|Bacteria,3Y4CJ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_2022528_6	383372.Rcas_3442	5.236e-09	69.0	COG3012@1|root,COG3012@2|Bacteria,2GACR@200795|Chloroflexi,375EK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM SEC-C motif domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
GDHHQS2_k127_2022528_1	234267.Acid_7816	4.542e-138	441.0	COG1482@1|root,COG1482@2|Bacteria,3Y6FR@57723|Acidobacteria	57723|Acidobacteria	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_202292_2	1340493.JNIF01000003_gene4745	2.85e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_202292_0	926566.Terro_0969	3.167e-130	425.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria,2JJVZ@204432|Acidobacteriia	204432|Acidobacteriia	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_202292_1	401053.AciPR4_0224	1.066e-80	277.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2028200_0	1210884.HG799463_gene9904	1.932e-74	263.0	COG5492@1|root,COG5492@2|Bacteria,2IX13@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_2028200_1	1123508.JH636445_gene6571	1.521e-52	195.0	COG4102@1|root,COG4102@2|Bacteria,2IX8B@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2029849_2	1236959.BAMT01000001_gene1494	6.041e-42	155.0	COG2154@1|root,COG2154@2|Bacteria,1RIEN@1224|Proteobacteria,2VRX8@28216|Betaproteobacteria,2KMW0@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS2_k127_2029849_1	1123393.KB891326_gene216	2.573e-70	244.0	COG1036@1|root,COG1036@2|Bacteria,1RD5I@1224|Proteobacteria,2VQ1A@28216|Betaproteobacteria,1KSD9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
GDHHQS2_k127_2029849_0	640511.BC1002_3215	1.214e-76	261.0	COG0294@1|root,COG0294@2|Bacteria,1MWM3@1224|Proteobacteria,2VH38@28216|Betaproteobacteria,1K05I@119060|Burkholderiaceae	28216|Betaproteobacteria	H	dihydropteroate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2031785_3	1340493.JNIF01000003_gene3829	1.487e-39	149.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2031785_0	1267535.KB906767_gene2856	4.053e-318	1006.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2031785_4	1230343.CANP01000018_gene1359	0.0008789	47.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
GDHHQS2_k127_2031785_2	1340493.JNIF01000003_gene2576	9.083e-55	213.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
GDHHQS2_k127_2031785_1	234267.Acid_2013	7.416e-207	659.0	COG2936@1|root,COG2936@2|Bacteria,3Y6W3@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_2033377_19	1148.1001561	1.708e-41	158.0	COG1208@1|root,COG1208@2|Bacteria,1G128@1117|Cyanobacteria,1H661@1142|Synechocystis	1117|Cyanobacteria	JM	MobA-like NTP transferase domain	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_2033377_22	1385517.N800_00445	1.892e-25	124.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1PH1W@1224|Proteobacteria,1RRYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,P_proprotein,Reprolysin_3,Reprolysin_4
GDHHQS2_k127_2033377_11	498761.HM1_1146	2.999e-110	366.0	COG2605@1|root,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia	186801|Clostridia	JM	GHMP kinase, N-terminal domain protein	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS2_k127_2033377_20	1121428.DESHY_110565___1	9.697e-40	168.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,2603G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
GDHHQS2_k127_2033377_18	864565.HMPREF0379_1619	1.836e-46	181.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia	186801|Clostridia	KLT	PFAM KWG Leptospira repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
GDHHQS2_k127_2033377_9	1267535.KB906767_gene568	3.68e-121	406.0	COG2148@1|root,COG2148@2|Bacteria,3Y4JY@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GDHHQS2_k127_2033377_17	234267.Acid_7018	2.279e-50	184.0	COG0698@1|root,COG0698@2|Bacteria,3Y5FG@57723|Acidobacteria	57723|Acidobacteria	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS2_k127_2033377_2	1267535.KB906767_gene3125	2.734e-214	674.0	COG0112@1|root,COG0112@2|Bacteria,3Y2JB@57723|Acidobacteria,2JI87@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS2_k127_2033377_4	234267.Acid_7016	2.497e-147	475.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2033377_15	234267.Acid_6428	1.333e-59	209.0	COG0590@1|root,COG0590@2|Bacteria,3Y4KB@57723|Acidobacteria	57723|Acidobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	DUF3175,MafB19-deam
GDHHQS2_k127_2033377_16	234267.Acid_4520	1.226e-58	209.0	COG1335@1|root,COG1335@2|Bacteria,3Y7ZP@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
GDHHQS2_k127_2033377_3	234267.Acid_4519	7.717e-168	540.0	COG1488@1|root,COG1488@2|Bacteria,3Y6U3@57723|Acidobacteria	57723|Acidobacteria	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
GDHHQS2_k127_2033377_10	234267.Acid_4518	7.004e-121	402.0	2ANCT@1|root,31DBC@2|Bacteria,3Y69A@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
GDHHQS2_k127_2033377_6	1382359.JIAL01000001_gene1267	2.584e-141	464.0	COG3225@1|root,COG3225@2|Bacteria,3Y6WR@57723|Acidobacteria	57723|Acidobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
GDHHQS2_k127_2033377_13	234267.Acid_4516	6.598e-98	327.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GDHHQS2_k127_2033377_8	234267.Acid_4515	2.821e-133	431.0	COG1131@1|root,COG1131@2|Bacteria,3Y6FZ@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_2033377_24	1267535.KB906767_gene5115	1.436e-17	97.0	COG2823@1|root,COG2823@2|Bacteria,3Y8T3@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS2_k127_2033377_0	1340493.JNIF01000003_gene3509	5.651e-254	797.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_2033377_1	234267.Acid_4106	6.039e-244	767.0	COG1807@1|root,COG1807@2|Bacteria,3Y404@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2033377_12	234267.Acid_4244	7.695e-105	351.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2033377_7	1210884.HG799464_gene11113	1.428e-139	452.0	COG3608@1|root,COG3608@2|Bacteria,2IXSR@203682|Planctomycetes	203682|Planctomycetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	3.5.1.125	ko:K15784	ko00260,ko01100,map00260,map01100	-	R09801	RC00064,RC00300	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
GDHHQS2_k127_2033377_5	566466.NOR53_670	6.981e-146	479.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1J7SK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_2033377_21	351016.RAZWK3B_11952	5.073e-38	146.0	COG1569@1|root,COG1569@2|Bacteria,1N1T4@1224|Proteobacteria,2UD1W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	nucleic acid-binding protein, contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS2_k127_2033377_23	56110.Oscil6304_6050	8.502e-22	97.0	2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria,1HDTG@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB,RHH_1
GDHHQS2_k127_2033377_14	234267.Acid_7660	2.269e-68	235.0	COG0167@1|root,COG1149@1|root,COG0167@2|Bacteria,COG1149@2|Bacteria,3Y3D8@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM Dihydroorotate dehydrogenase	-	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
GDHHQS2_k127_2039798_3	1267535.KB906767_gene1747	2.068e-12	68.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_2039798_1	234267.Acid_5662	1.014e-57	204.0	COG1576@1|root,COG1576@2|Bacteria,3Y54B@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
GDHHQS2_k127_2039798_4	1137799.GZ78_24930	0.0006968	44.0	COG1106@1|root,COG1475@1|root,COG1106@2|Bacteria,COG1475@2|Bacteria,1NER1@1224|Proteobacteria,1SFR8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,ParBc
GDHHQS2_k127_2039798_0	1340493.JNIF01000003_gene3961	9.79e-201	657.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_2039798_2	1097668.BYI23_B015380	8.817e-26	109.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,1K590@119060|Burkholderiaceae	28216|Betaproteobacteria	S	penicillin amidase	penA	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_2045017_0	1403819.BATR01000105_gene3643	2.115e-78	273.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_2045017_1	1123508.JH636443_gene4545	2.125e-15	83.0	COG2165@1|root,COG2165@2|Bacteria,2IXVQ@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS2_k127_204720_1	395961.Cyan7425_3419	2.086e-57	205.0	COG2006@1|root,COG2006@2|Bacteria,1G0X0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS2_k127_204720_2	134676.ACPL_5842	2.885e-21	100.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
GDHHQS2_k127_204720_3	1054860.KB913030_gene6567	4.419e-09	66.0	COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
GDHHQS2_k127_204720_4	134676.ACPL_5842	2.178e-08	64.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
GDHHQS2_k127_204720_0	639030.JHVA01000001_gene2668	1.499e-98	332.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_2053653_1	1267534.KB906754_gene3823	5.436e-37	144.0	COG2318@1|root,COG2318@2|Bacteria,3Y594@57723|Acidobacteria,2JJNR@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_2053653_0	1267534.KB906754_gene3822	4.808e-43	165.0	COG3832@1|root,COG3832@2|Bacteria,3Y5QW@57723|Acidobacteria	57723|Acidobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_2053653_2	1267534.KB906754_gene3821	2.558e-33	132.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS2_k127_2055841_4	1340493.JNIF01000003_gene2328	9.056e-20	98.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_2055841_1	926554.KI912627_gene1165	1.367e-115	383.0	COG3173@1|root,COG3173@2|Bacteria,1WJ1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS2_k127_2055841_3	287.DR97_48	3.028e-30	130.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,1SAC4@1236|Gammaproteobacteria,1YD1E@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS2_k127_2055841_0	926554.KI912666_gene1495	2.971e-200	629.0	COG1960@1|root,COG1960@2|Bacteria,1WIQZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Acyl-coa dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_2055841_2	243230.DR_A0193	9.002e-56	202.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS2_k127_2055841_5	1267535.KB906767_gene2719	8.987e-14	74.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
GDHHQS2_k127_2056126_1	1267535.KB906767_gene1348	1.663e-56	203.0	COG3534@1|root,COG3534@2|Bacteria,3Y48A@57723|Acidobacteria,2JKQ1@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS2_k127_2056126_0	543632.JOJL01000014_gene9230	5.247e-134	444.0	2EX9M@1|root,33QKC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2059068_2	1267535.KB906767_gene3195	9.859e-102	334.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS2_k127_2059068_1	1392502.JNIO01000008_gene1982	1.642e-116	389.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
GDHHQS2_k127_2059068_3	234267.Acid_1209	2.048e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_2059068_0	1183438.GKIL_3395	1.792e-144	482.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_206063_0	1267535.KB906767_gene4517	2.046e-125	407.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	gbd	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_206063_1	1267535.KB906767_gene444	5.397e-115	377.0	COG0673@1|root,COG0673@2|Bacteria,3Y4BF@57723|Acidobacteria,2JKZN@204432|Acidobacteriia	204432|Acidobacteriia	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2061955_2	1123508.JH636443_gene4822	1.291e-176	568.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2061955_1	1340493.JNIF01000003_gene1966	8.543e-228	713.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2061955_0	234267.Acid_4268	1.36e-258	822.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2063419_0	861299.J421_1112	9.242e-69	238.0	COG0534@1|root,COG0534@2|Bacteria,1ZT3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS2_k127_2063419_1	316273.XCV2014	1.827e-10	63.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1X3YG@135614|Xanthomonadales	135614|Xanthomonadales	T	Fis family transcriptional regulator	fleQ	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
GDHHQS2_k127_2075879_0	1267535.KB906767_gene2855	9.947e-214	687.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat,TonB_dep_Rec
GDHHQS2_k127_2075879_1	316274.Haur_4136	1.931e-17	83.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi,37610@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_2084306_5	1340493.JNIF01000003_gene2091	5.498e-10	63.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_2084306_3	1340493.JNIF01000003_gene3836	4.188e-38	158.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_2084306_0	234267.Acid_1490	2.726e-239	758.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS2_k127_2084306_4	234267.Acid_1189	7.166e-14	81.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2084306_1	143224.JQMD01000002_gene209	3.05e-204	653.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
GDHHQS2_k127_2084306_2	1449065.JMLL01000010_gene1152	1.93e-52	201.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,43I2S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihA	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS2_k127_2092868_2	177437.HRM2_13290	8.308e-27	126.0	COG0457@1|root,COG0457@2|Bacteria,1MW49@1224|Proteobacteria,42N7T@68525|delta/epsilon subdivisions,2WK4Z@28221|Deltaproteobacteria,2MJ6P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2092868_3	1502852.FG94_00170	9.902e-09	64.0	COG4935@1|root,COG4935@2|Bacteria,1RK8D@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4215,PPC,P_proprotein
GDHHQS2_k127_2092868_1	318996.AXAZ01000059_gene1183	5.261e-122	398.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2TTP9@28211|Alphaproteobacteria,3JW7T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2092868_0	35754.JNYJ01000010_gene1591	7.645e-125	413.0	COG3934@1|root,COG3934@2|Bacteria,2IC0X@201174|Actinobacteria,4DBJ0@85008|Micromonosporales	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase
GDHHQS2_k127_2096207_6	1144275.COCOR_00405	3.298e-42	162.0	COG3950@1|root,COG3950@2|Bacteria,1QC47@1224|Proteobacteria,43E72@68525|delta/epsilon subdivisions,2WZWB@28221|Deltaproteobacteria,2YZPQ@29|Myxococcales	28221|Deltaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
GDHHQS2_k127_2096207_0	234267.Acid_1922	2.063e-221	695.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2096207_2	234267.Acid_1921	6.324e-106	377.0	COG3852@1|root,COG3852@2|Bacteria,3Y9A1@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2096207_1	1267535.KB906767_gene4063	1.663e-192	616.0	COG0539@1|root,COG0539@2|Bacteria,3Y3P3@57723|Acidobacteria,2JI5R@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_2096207_3	1340493.JNIF01000003_gene3266	3.937e-84	284.0	COG1595@1|root,COG1595@2|Bacteria,3Y4CH@57723|Acidobacteria	57723|Acidobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_2096207_8	1267533.KB906741_gene529	5.987e-26	119.0	COG1413@1|root,COG1413@2|Bacteria,3Y2TB@57723|Acidobacteria,2JHKS@204432|Acidobacteriia	204432|Acidobacteriia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
GDHHQS2_k127_2096207_9	518766.Rmar_0974	1.454e-13	83.0	COG3595@1|root,COG3595@2|Bacteria,4PFA3@976|Bacteroidetes,1FKCN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_2096207_5	1340493.JNIF01000003_gene3264	1.366e-61	222.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria	57723|Acidobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
GDHHQS2_k127_2096207_7	1340493.JNIF01000003_gene2321	8.97e-38	155.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2096207_4	1340493.JNIF01000003_gene2321	7.796e-77	270.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2098537_0	1379698.RBG1_1C00001G0614	2.765e-133	434.0	COG1505@1|root,COG1505@2|Bacteria,2NNUB@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_2098537_1	886293.Sinac_7310	1.639e-92	310.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_2098537_2	240015.ACP_0992	3.662e-09	60.0	COG0457@1|root,COG0457@2|Bacteria	240015.ACP_0992|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2102017_1	234267.Acid_1243	1.667e-110	364.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_2102017_0	1340493.JNIF01000003_gene3565	3.518e-146	490.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2109049_3	563192.HMPREF0179_00160	3.685e-10	64.0	COG0863@1|root,COG0863@2|Bacteria,1RAU2@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Eco29kI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_Eco29kI
GDHHQS2_k127_2109049_4	759362.KVU_0252	5.323e-10	64.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2UA6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
GDHHQS2_k127_2109049_0	204669.Acid345_2039	4.144e-174	566.0	COG0145@1|root,COG0145@2|Bacteria,3Y6D5@57723|Acidobacteria,2JKXC@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
GDHHQS2_k127_2109049_1	234267.Acid_3571	4.936e-62	220.0	COG0558@1|root,COG0558@2|Bacteria,3Y4PW@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_2109049_2	1267535.KB906767_gene5063	8.366e-18	97.0	COG2246@1|root,COG2246@2|Bacteria,3Y5HC@57723|Acidobacteria,2JJXS@204432|Acidobacteriia	204432|Acidobacteriia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
GDHHQS2_k127_2109049_6	404589.Anae109_2257	0.0009594	44.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_2117170_0	379066.GAU_2577	0.0	1158.0	COG1629@1|root,COG4771@2|Bacteria,1ZSNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2118462_0	383372.Rcas_3850	2.553e-70	262.0	COG2133@1|root,COG2133@2|Bacteria,2G90Z@200795|Chloroflexi	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_212102_1	1123242.JH636434_gene5367	4.028e-134	443.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_212102_0	1340493.JNIF01000003_gene3464	7.661e-136	445.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_212102_2	1340493.JNIF01000003_gene3464	2.008e-22	99.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2128312_2	1049564.TevJSym_bb00030	1.907e-35	150.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
GDHHQS2_k127_2128312_1	1242864.D187_007278	1.271e-61	231.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,MFS_1
GDHHQS2_k127_2128312_0	234267.Acid_6834	9.823e-129	426.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_2129244_3	1120919.AUBI01000002_gene1220	4.125e-68	242.0	2EE0X@1|root,337VQ@2|Bacteria,1N7Y3@1224|Proteobacteria,2UGEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2129244_2	329726.AM1_5361	1.899e-69	243.0	COG1187@1|root,COG1187@2|Bacteria,1G56K@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS2_k127_2129244_1	204669.Acid345_3040	1.851e-161	522.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_2129244_0	234267.Acid_7736	2.507e-185	604.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
GDHHQS2_k127_2129244_4	1173028.ANKO01000051_gene1566	6.711e-05	46.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria,1HD9S@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_2129244_5	1254432.SCE1572_48940	0.0004207	45.0	COG4634@1|root,COG4634@2|Bacteria,1RH7A@1224|Proteobacteria,42U78@68525|delta/epsilon subdivisions,2WQJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2130200_0	1267535.KB906767_gene3685	1.75e-60	230.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria,2JHIB@204432|Acidobacteriia	204432|Acidobacteriia	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS2_k127_2130200_1	1340493.JNIF01000003_gene1936	1.446e-42	160.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	adhA7	-	1.1.1.1,1.1.1.264,1.1.1.303,1.1.1.4	ko:K00001,ko:K00004,ko:K00098	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02855,R02946,R04805,R04880,R05233,R05234,R05684,R06917,R06927,R07105,R08281,R08306,R08310,R10504	RC00050,RC00087,RC00088,RC00089,RC00099,RC00116,RC00205,RC00525,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
GDHHQS2_k127_213404_0	743721.Psesu_0869	2.514e-33	135.0	28MQB@1|root,32M39@2|Bacteria,1NT28@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2134508_2	768671.ThimaDRAFT_3232	9.57e-05	46.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X00P@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2134508_1	1340493.JNIF01000003_gene3264	3.989e-28	125.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria	57723|Acidobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
GDHHQS2_k127_2134508_0	1379270.AUXF01000002_gene1477	5.124e-30	125.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS2_k127_2141922_0	234267.Acid_3353	3.713e-237	745.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria	57723|Acidobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GDHHQS2_k127_2142183_2	479434.Sthe_0723	8.075e-38	157.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,27YU9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
GDHHQS2_k127_2142183_0	1340493.JNIF01000004_gene331	9.11e-100	349.0	COG0603@1|root,COG0603@2|Bacteria,3Y3RP@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS2_k127_2142183_1	1340493.JNIF01000004_gene330	1.197e-77	265.0	COG0602@1|root,COG0602@2|Bacteria,3Y2UA@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
GDHHQS2_k127_2142250_2	1340493.JNIF01000003_gene4600	1.583e-63	238.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2142250_0	575540.Isop_2381	1.452e-167	553.0	COG2010@1|root,COG2010@2|Bacteria,2IWY5@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2142250_1	886293.Sinac_4600	1.427e-163	529.0	COG4102@1|root,COG4102@2|Bacteria,2IYDS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2142250_3	1123401.JHYQ01000001_gene1725	1.699e-45	170.0	2DZKR@1|root,32VDB@2|Bacteria,1RBUG@1224|Proteobacteria,1SVAY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2145682_2	1267535.KB906767_gene1499	6.137e-10	61.0	COG4591@1|root,COG4591@2|Bacteria,3Y3DS@57723|Acidobacteria,2JHS5@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2145682_0	1340493.JNIF01000003_gene3900	4.081e-220	688.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_2145682_1	1218108.KB908292_gene1703	7.76e-31	128.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_2149706_6	401053.AciPR4_2257	6.752e-145	475.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria,2JMM3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2149706_10	234267.Acid_5334	2.417e-68	244.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_5334|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2149706_12	234267.Acid_0699	3.99e-44	170.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_2149706_7	1254432.SCE1572_02795	1.529e-121	408.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_2149706_9	639030.JHVA01000001_gene2540	1.349e-97	328.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_2149706_0	316274.Haur_0703	0.0	1080.0	COG0826@1|root,COG0826@2|Bacteria,2G8DM@200795|Chloroflexi,376GI@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
GDHHQS2_k127_2149706_3	234267.Acid_2098	5.675e-186	590.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_2149706_1	497964.CfE428DRAFT_4339	1.238e-290	915.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,PP-binding,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_2149706_2	234267.Acid_7573	2.553e-290	927.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2149706_15	1353528.DT23_11325	0.0005899	51.0	COG0457@1|root,COG0457@2|Bacteria,1N0DE@1224|Proteobacteria,2UCGA@28211|Alphaproteobacteria,2XMTY@285107|Thioclava	28211|Alphaproteobacteria	S	Tetratricopeptide repeats	MA20_05980	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_2149706_8	234267.Acid_5045	1.237e-103	343.0	COG1082@1|root,COG1082@2|Bacteria,3Y61S@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2149706_11	485917.Phep_3107	2.749e-51	206.0	COG3401@1|root,COG3401@2|Bacteria	2|Bacteria	Q	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS2_k127_2149706_14	234267.Acid_6974	2.794e-08	61.0	2FGSP@1|root,348N1@2|Bacteria,3Y8G3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2149706_4	593117.TGAM_1505	1.894e-167	539.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,24310@183968|Thermococci	183968|Thermococci	J	tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
GDHHQS2_k127_2149706_13	515635.Dtur_1264	8.485e-21	97.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
GDHHQS2_k127_2149706_5	1267535.KB906767_gene1811	4.199e-156	502.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_2150114_0	861299.J421_2757	2.596e-149	478.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS2_k127_2150114_7	379066.GAU_0848	1.782e-23	99.0	COG0267@1|root,COG0267@2|Bacteria,1ZV8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GDHHQS2_k127_2150114_2	861299.J421_2762	5.012e-87	294.0	COG0250@1|root,COG0250@2|Bacteria,1ZSS2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
GDHHQS2_k127_2150114_4	1120746.CCNL01000009_gene1033	3.108e-60	210.0	COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS2_k127_2150114_1	635013.TherJR_0284	1.715e-90	305.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,260G7@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS2_k127_2150114_3	861299.J421_2765	1.753e-70	246.0	COG0244@1|root,COG0244@2|Bacteria,1ZTQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GDHHQS2_k127_2150114_6	861299.J421_2766	8.52e-60	210.0	COG0222@1|root,COG0222@2|Bacteria,1ZTTC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS2_k127_2150114_5	861299.J421_2767	6.764e-60	208.0	COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS2_k127_2155217_0	1961.JOAK01000003_gene1705	3.59e-40	173.0	COG0726@1|root,COG0726@2|Bacteria,2I3D0@201174|Actinobacteria	201174|Actinobacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GDHHQS2_k127_2155217_1	1120973.AQXL01000096_gene3002	5.972e-38	150.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,279IG@186823|Alicyclobacillaceae	91061|Bacilli	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_2162006_1	634497.HAH_1320	5.777e-44	166.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23T7A@183963|Halobacteria	183963|Halobacteria	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_2162006_0	289376.THEYE_A1970	3.992e-59	218.0	COG3264@1|root,COG3264@2|Bacteria,3J0R7@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
GDHHQS2_k127_2162006_4	1121024.AUCD01000001_gene1726	1.964e-11	75.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,27FFR@186828|Carnobacteriaceae	91061|Bacilli	L	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_2162006_3	1231391.AMZF01000070_gene2137	9.84e-25	111.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VTNA@28216|Betaproteobacteria,3T4QQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	rnz	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
GDHHQS2_k127_2162006_2	1340493.JNIF01000003_gene3989	1.607e-35	153.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
GDHHQS2_k127_2162006_6	240015.ACP_1398	2.217e-09	63.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZU@57723|Acidobacteria,2JHPF@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2162006_7	1267534.KB906757_gene1074	8.557e-08	61.0	COG1629@1|root,COG1629@2|Bacteria,3Y72I@57723|Acidobacteria,2JKKK@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2168431_2	1340493.JNIF01000003_gene1982	1.673e-129	427.0	COG3127@1|root,COG3127@2|Bacteria,3Y2PA@57723|Acidobacteria	57723|Acidobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2168431_3	1267535.KB906767_gene3344	7.257e-124	404.0	COG0276@1|root,COG0276@2|Bacteria,3Y3B0@57723|Acidobacteria,2JHKQ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
GDHHQS2_k127_2168431_6	452637.Oter_0624	9.946e-41	163.0	COG3428@1|root,COG3428@2|Bacteria,46VTZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
GDHHQS2_k127_2168431_5	452637.Oter_0623	2.847e-47	174.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
GDHHQS2_k127_2168431_1	1267535.KB906767_gene1814	1.481e-216	706.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria,2JM2Q@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2168431_4	1288963.ADIS_0477	2.949e-57	226.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
GDHHQS2_k127_2168431_7	1121472.AQWN01000007_gene1168	2.365e-32	134.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,260IE@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_2168431_0	1121904.ARBP01000029_gene2184	1.152e-230	739.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2177055_3	420324.KI912006_gene8707	1.779e-22	98.0	COG0395@1|root,COG0395@2|Bacteria,1PJQT@1224|Proteobacteria,2TU8F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type sugar transport system, permease component	MA20_14020	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GDHHQS2_k127_2177055_1	420324.KI912006_gene8708	3.589e-139	446.0	COG1175@1|root,COG1175@2|Bacteria,1NAGS@1224|Proteobacteria,2TUXQ@28211|Alphaproteobacteria,1JXZA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	MA20_14025	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
GDHHQS2_k127_2177055_0	420324.KI912006_gene8709	2.139e-197	624.0	COG1653@1|root,COG1653@2|Bacteria,1N98V@1224|Proteobacteria,2TSIS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	msmE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_2177055_2	420324.KI912006_gene8711	2.76e-80	270.0	COG0673@1|root,COG0673@2|Bacteria,1MVT5@1224|Proteobacteria,2TV1T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	MA20_14015	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_2185209_5	40571.JOEA01000004_gene6440	2.767e-15	77.0	COG0047@1|root,COG0047@2|Bacteria	2|Bacteria	F	phosphoribosylformylglycinamidine synthase activity	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
GDHHQS2_k127_2185209_0	1340493.JNIF01000003_gene1861	4.376e-176	583.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_2185209_3	1123242.JH636434_gene5626	3.595e-63	233.0	COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,Flg_new,LRR_5,LRR_6
GDHHQS2_k127_2185209_4	234267.Acid_3083	3.811e-61	220.0	COG3595@1|root,COG3595@2|Bacteria,3Y5AF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2185209_2	1297742.A176_07251	4.262e-68	253.0	2BVHD@1|root,32QVZ@2|Bacteria,1N6CE@1224|Proteobacteria,430V5@68525|delta/epsilon subdivisions,2X3NG@28221|Deltaproteobacteria,2YWNE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2185209_1	497964.CfE428DRAFT_1056	1.019e-139	458.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
GDHHQS2_k127_2189551_1	1340493.JNIF01000003_gene2166	1.016e-11	66.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2189551_0	234267.Acid_3906	7.432e-93	319.0	COG0673@1|root,COG0673@2|Bacteria,3Y66I@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_2189551_2	1034943.BN1094_03415	3.379e-11	71.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,1JE01@118969|Legionellales	118969|Legionellales	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_2192196_2	1267535.KB906767_gene1827	5.294e-47	178.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2192196_1	1267535.KB906767_gene218	2.395e-152	492.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2192196_0	1340493.JNIF01000003_gene3603	2.923e-181	575.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2192196_4	1340493.JNIF01000004_gene946	4.247e-39	154.0	COG0637@1|root,COG0637@2|Bacteria,3Y49E@57723|Acidobacteria	57723|Acidobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_2192196_3	1267535.KB906767_gene5041	1.257e-41	164.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZC@57723|Acidobacteria,2JK8R@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2193201_0	1123508.JH636443_gene4822	3.948e-174	559.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2193201_1	234267.Acid_4712	8.104e-143	467.0	COG1052@1|root,COG1052@2|Bacteria,3Y4PG@57723|Acidobacteria	57723|Acidobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_2193201_2	1340493.JNIF01000003_gene3464	4.686e-115	378.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2194720_2	204669.Acid345_4244	7.06e-12	73.0	COG1595@1|root,COG1595@2|Bacteria,3Y58Z@57723|Acidobacteria,2JN7R@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
GDHHQS2_k127_2194720_1	1340493.JNIF01000004_gene796	3.018e-47	181.0	COG1357@1|root,COG1357@2|Bacteria,3Y96A@57723|Acidobacteria	57723|Acidobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_2194720_0	234267.Acid_6506	9.677e-80	274.0	COG3503@1|root,COG3503@2|Bacteria,3Y73K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS2_k127_2195857_2	234267.Acid_6854	4.832e-127	425.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2195857_3	1340493.JNIF01000004_gene449	5.213e-69	242.0	COG0663@1|root,COG0663@2|Bacteria,3Y4A5@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS2_k127_2195857_1	1267535.KB906767_gene1020	3.887e-188	599.0	COG0124@1|root,COG0124@2|Bacteria,3Y3IY@57723|Acidobacteria,2JIRJ@204432|Acidobacteriia	204432|Acidobacteriia	J	synthetase, class II (G H P	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS2_k127_2195857_0	234267.Acid_1538	3.152e-293	909.0	COG0173@1|root,COG0173@2|Bacteria,3Y3SP@57723|Acidobacteria	57723|Acidobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_2206101_0	1121405.dsmv_3003	0.0	1405.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS2_k127_2210573_0	234267.Acid_3977	4.83e-155	507.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2210762_0	338963.Pcar_1381	2.635e-78	268.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
GDHHQS2_k127_2210762_1	338963.Pcar_1382	1.085e-34	135.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
GDHHQS2_k127_2210762_3	561229.Dd1591_0446	0.0003462	48.0	2B14P@1|root,31TII@2|Bacteria,1QR95@1224|Proteobacteria,1SN3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GDHHQS2_k127_2210762_2	44056.XP_009033911.1	3.922e-25	117.0	COG0661@1|root,COG0814@1|root,KOG1235@2759|Eukaryota,KOG1304@2759|Eukaryota	2759|Eukaryota	E	amino acid transmembrane transporter activity	-	-	-	ko:K08869,ko:K14209	ko04138,map04138	-	-	-	ko00000,ko00001,ko01001,ko02000,ko04131	2.A.18.8	-	-	ABC1,Aa_trans,Ras,SH2
GDHHQS2_k127_2214492_0	1340493.JNIF01000003_gene2760	0.0	1150.0	COG2067@1|root,COG2067@2|Bacteria,3Y41G@57723|Acidobacteria	57723|Acidobacteria	I	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2217941_2	234267.Acid_4948	1.619e-06	54.0	COG5649@1|root,COG5649@2|Bacteria,3Y94P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2217941_0	234267.Acid_0357	2.506e-143	469.0	COG0402@1|root,COG0402@2|Bacteria,3Y69W@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_2217941_1	1340493.JNIF01000004_gene927	9.991e-117	385.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_2221432_0	234267.Acid_0987	2.047e-200	632.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,3Y2UX@57723|Acidobacteria	57723|Acidobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K13503,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
GDHHQS2_k127_2221432_1	243090.RB3767	5.317e-121	398.0	COG0473@1|root,COG0473@2|Bacteria,2IXJZ@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_2221432_3	330084.JNYZ01000066_gene4988	7.253e-50	192.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_2221432_2	1340493.JNIF01000003_gene3464	1.361e-106	362.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2222402_2	234267.Acid_0687	3.012e-53	196.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
GDHHQS2_k127_2222402_1	234267.Acid_7892	8.167e-105	354.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_2222402_0	234267.Acid_7891	1.367e-196	629.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_223042_0	1340493.JNIF01000003_gene4562	9.142e-205	643.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GDHHQS2_k127_223042_1	234267.Acid_4068	1.391e-181	574.0	COG0473@1|root,COG0473@2|Bacteria,3Y38Z@57723|Acidobacteria	57723|Acidobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_223042_2	1267535.KB906767_gene3363	3.104e-61	213.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria,2JI0S@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GDHHQS2_k127_2251125_0	886293.Sinac_7009	0.0	1283.0	COG2010@1|root,COG2010@2|Bacteria,2IY6K@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2251125_1	886293.Sinac_7008	3.893e-133	428.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2253313_4	1403819.BATR01000135_gene4814	6.932e-62	239.0	COG4409@1|root,COG4409@2|Bacteria,46WX2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_2253313_5	203122.Sde_2315	7.651e-29	134.0	COG4409@1|root,COG4409@2|Bacteria,1R5QN@1224|Proteobacteria,1T31W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_2253313_3	314230.DSM3645_06014	1.052e-136	454.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_2253313_1	1340493.JNIF01000003_gene2575	7.404e-222	728.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2253313_0	234267.Acid_1145	6.502e-246	782.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2253313_2	234267.Acid_1146	1.77e-206	651.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2259971_0	1095769.CAHF01000022_gene253	1.922e-154	507.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_2259971_1	234267.Acid_6001	4.657e-10	60.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,3Y5BB@57723|Acidobacteria	57723|Acidobacteria	N	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
GDHHQS2_k127_2267722_2	1340493.JNIF01000004_gene706	1.101e-35	140.0	COG1815@1|root,COG1815@2|Bacteria,3Y5BH@57723|Acidobacteria	57723|Acidobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
GDHHQS2_k127_2267722_1	234267.Acid_0338	1.352e-55	203.0	COG1558@1|root,COG1558@2|Bacteria,3Y538@57723|Acidobacteria	57723|Acidobacteria	N	flagellar basal-body rod protein FlgC	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS2_k127_2267722_4	234267.Acid_0339	2.507e-13	76.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
GDHHQS2_k127_2267722_0	234267.Acid_0340	7.818e-151	496.0	COG1766@1|root,COG1766@2|Bacteria,3Y2HU@57723|Acidobacteria	57723|Acidobacteria	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
GDHHQS2_k127_2267722_3	1267535.KB906767_gene4608	4.27e-23	100.0	COG1536@1|root,COG1536@2|Bacteria,3Y2U7@57723|Acidobacteria,2JIY7@204432|Acidobacteriia	204432|Acidobacteriia	N	flagellar motor switch protein FliG	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
GDHHQS2_k127_2271232_8	1047013.AQSP01000125_gene2637	3.699e-50	202.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
GDHHQS2_k127_2271232_5	234267.Acid_4320	2.31e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2271232_7	234267.Acid_4321	8.844e-55	202.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2271232_14	234267.Acid_4321	2.072e-16	91.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2271232_6	1120949.KB903324_gene3346	2.373e-66	243.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4DCCD@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
GDHHQS2_k127_2271232_0	234267.Acid_3616	3.46e-192	605.0	COG0436@1|root,COG0436@2|Bacteria,3Y2TF@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_2271232_13	272123.Anacy_1523	3.071e-21	97.0	COG4634@1|root,COG4634@2|Bacteria,1G86B@1117|Cyanobacteria,1HPFD@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271232_12	1469607.KK073768_gene757	7.932e-26	111.0	COG2442@1|root,COG2442@2|Bacteria,1G8S8@1117|Cyanobacteria,1HQ3Q@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_2271232_16	1434325.AZQN01000010_gene3965	2.834e-07	64.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_2271232_15	234267.Acid_4319	1.886e-12	81.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	ripA	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K05804	-	M00647,M00767	-	-	ko00000,ko00002,ko03000,ko03036	-	-	-	HTH_18,Reg_prop,Response_reg,Y_Y_Y
GDHHQS2_k127_2271232_4	234267.Acid_4320	8.11e-85	286.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2271232_1	234267.Acid_4321	2.679e-125	423.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2271232_11	870187.Thini_3802	2.103e-29	126.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cccE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_2271232_2	247633.GP2143_17796	3.756e-113	374.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271232_3	247633.GP2143_17791	4.123e-106	356.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271232_17	227086.JGI_V11_43966	2.211e-05	54.0	COG0790@1|root,KOG1550@2759|Eukaryota	227086.JGI_V11_43966|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271232_10	1340493.JNIF01000004_gene976	7.154e-34	132.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_2271314_5	1340493.JNIF01000003_gene3027	5.02e-09	59.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria	57723|Acidobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
GDHHQS2_k127_2271314_0	234267.Acid_1311	2.971e-82	282.0	COG0631@1|root,COG0631@2|Bacteria,3Y7SC@57723|Acidobacteria	57723|Acidobacteria	T	Protein phosphatase 2C	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS2_k127_2271314_3	1267535.KB906767_gene2968	4.402e-22	106.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271314_2	234267.Acid_1313	3.512e-48	190.0	COG1361@1|root,COG1361@2|Bacteria,3Y8BF@57723|Acidobacteria	57723|Acidobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2271314_4	395493.BegalDRAFT_3419	8.037e-10	64.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1QZXZ@1224|Proteobacteria,1SDZ2@1236|Gammaproteobacteria,463A3@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
GDHHQS2_k127_2271314_1	518766.Rmar_0409	5.729e-74	258.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
GDHHQS2_k127_2282932_1	1532558.JL39_23260	1.426e-07	52.0	COG3795@1|root,COG3795@2|Bacteria,1RDGG@1224|Proteobacteria,2UAZN@28211|Alphaproteobacteria,4BES0@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS2_k127_2282932_0	717785.HYPMC_3257	1.411e-175	558.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3N8ZI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
GDHHQS2_k127_2292944_0	1123508.JH636453_gene5802	8.276e-62	245.0	COG3210@1|root,COG3391@1|root,COG3827@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3827@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS2_k127_2292944_1	1123073.KB899245_gene23	7.68e-32	146.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_2292944_2	338966.Ppro_1566	2.353e-21	108.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_2294789_1	1267535.KB906767_gene1468	2.059e-16	82.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2294789_0	886293.Sinac_7090	4.235e-84	295.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2300048_0	886293.Sinac_7587	3.908e-109	357.0	COG4102@1|root,COG4102@2|Bacteria,2IY2D@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2300048_2	1303518.CCALI_01104	4.736e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS2_k127_2300048_1	1192034.CAP_2677	3.251e-12	68.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_2304562_0	886293.Sinac_4591	3.722e-189	599.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2304562_1	234267.Acid_2405	7.972e-120	402.0	COG4932@1|root,COG4932@2|Bacteria,3Y73S@57723|Acidobacteria	2|Bacteria	M	PFAM Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
GDHHQS2_k127_2306181_3	234267.Acid_2975	3.118e-53	211.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2306181_2	1267535.KB906767_gene4120	8.379e-66	240.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JP0E@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2306181_0	497964.CfE428DRAFT_3511	2.885e-107	356.0	COG3836@1|root,COG3836@2|Bacteria,46V5P@74201|Verrucomicrobia	74201|Verrucomicrobia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_2306181_4	234267.Acid_0195	2.06e-50	193.0	COG1802@1|root,COG1802@2|Bacteria,3Y849@57723|Acidobacteria	57723|Acidobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_2312105_0	234267.Acid_6001	2.216e-89	308.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,3Y5BB@57723|Acidobacteria	57723|Acidobacteria	N	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
GDHHQS2_k127_2313808_1	264462.Bd3697	0.0001428	55.0	COG0846@1|root,COG0846@2|Bacteria,1MW6J@1224|Proteobacteria,43EZW@68525|delta/epsilon subdivisions,2MTTZ@213481|Bdellovibrionales,2X2SV@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
GDHHQS2_k127_2313808_0	1267535.KB906767_gene1458	1.668e-32	128.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS2_k127_2334430_0	1340493.JNIF01000003_gene3109	1.59e-181	574.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_2334430_3	1333998.M2A_2447	7.582e-22	104.0	COG0346@1|root,COG0346@2|Bacteria,1MZXF@1224|Proteobacteria,2UBSQ@28211|Alphaproteobacteria,4BSKW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_2334430_1	344747.PM8797T_06150	1.86e-123	412.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2334430_2	1123508.JH636442_gene3868	9.032e-40	153.0	COG1959@1|root,COG1959@2|Bacteria,2IZQA@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS2_k127_2334430_4	1146883.BLASA_1764	5.288e-19	91.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria,4EWYP@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_2335704_1	234267.Acid_4944	3.972e-106	351.0	COG0531@1|root,COG0531@2|Bacteria,3Y3SZ@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_2335704_3	234267.Acid_4942	1.98e-60	215.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria	57723|Acidobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS2_k127_2335704_4	1382356.JQMP01000001_gene940	6.351e-51	190.0	COG3718@1|root,COG3718@2|Bacteria,2G708@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Myo-inositol catabolism IolB domain protein	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
GDHHQS2_k127_2335704_0	595460.RRSWK_05056	1.899e-157	508.0	COG4102@1|root,COG4102@2|Bacteria,2IY0X@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2335704_2	530564.Psta_0233	5.185e-83	287.0	COG0845@1|root,COG0845@2|Bacteria,2J54Q@203682|Planctomycetes	203682|Planctomycetes	M	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2335812_2	1267535.KB906767_gene4080	3.383e-17	81.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria,2JHXA@204432|Acidobacteriia	204432|Acidobacteriia	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_2335812_3	1298598.JCM21714_1159	0.0001183	55.0	2BXG3@1|root,2Z82R@2|Bacteria,1TQT7@1239|Firmicutes,4HDJZ@91061|Bacilli,4707Y@74385|Gracilibacillus	91061|Bacilli	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
GDHHQS2_k127_2335812_0	234267.Acid_0605	4.153e-205	657.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_2354507_2	1267535.KB906767_gene2426	3.105e-195	621.0	COG0696@1|root,COG0696@2|Bacteria,3Y2YH@57723|Acidobacteria,2JIZ0@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GDHHQS2_k127_2354507_1	1340493.JNIF01000003_gene4028	9.8e-199	627.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS2_k127_2354507_8	1340493.JNIF01000003_gene2174	9.913e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Z3@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2354507_6	1267535.KB906767_gene5125	5.973e-67	243.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Q6@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2354507_0	234267.Acid_5431	0.0	1087.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2354507_7	743719.PaelaDRAFT_1826	1.824e-49	184.0	COG1028@1|root,COG1028@2|Bacteria,1UY5Y@1239|Firmicutes,4HE3G@91061|Bacilli,26QCY@186822|Paenibacillaceae	91061|Bacilli	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_2354507_3	1267535.KB906767_gene3362	1.032e-141	456.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria,2JIC0@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS2_k127_2354507_4	1288963.ADIS_1259	2.308e-138	454.0	COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2354507_5	886293.Sinac_7090	8.384e-114	396.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2354507_9	1173021.ALWA01000028_gene1996	3.887e-37	145.0	COG4276@1|root,COG4276@2|Bacteria,1G60I@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
GDHHQS2_k127_2354507_10	1161401.ASJA01000011_gene1501	7.38e-36	147.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UDUB@28211|Alphaproteobacteria,43YPJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
GDHHQS2_k127_2354738_0	1340493.JNIF01000004_gene1047	1.168e-198	634.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2354738_3	626418.bglu_1g33450	1.959e-08	63.0	COG3295@1|root,COG3295@2|Bacteria,1RF14@1224|Proteobacteria,2VSCE@28216|Betaproteobacteria,1JZTQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM PepSY-associated TM helix domain protein	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
GDHHQS2_k127_2354738_4	28072.Nos7524_4143	0.0002141	51.0	COG0515@1|root,COG0515@2|Bacteria,1G1ZA@1117|Cyanobacteria,1HKYQ@1161|Nostocales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2354738_1	234267.Acid_6854	8.928e-61	214.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2354824_0	264731.PRU_1664	9.423e-59	226.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,2FR1I@200643|Bacteroidia	976|Bacteroidetes	O	ATPase, AAA family	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_2358730_0	330214.NIDE2455	1.389e-112	371.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	preT	-	1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00528,ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R10159,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,GXGXG,Pyr_redox_2,Pyr_redox_3
GDHHQS2_k127_2358730_1	555079.Toce_0272	2.446e-53	200.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,42F5G@68295|Thermoanaerobacterales	186801|Clostridia	H	MoeA domain protein domain I and II	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS2_k127_2358730_2	290397.Adeh_2361	1.841e-05	52.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GDHHQS2_k127_2363029_0	240016.ABIZ01000001_gene4015	5.936e-184	590.0	COG2133@1|root,COG2133@2|Bacteria,46UJH@74201|Verrucomicrobia,2IVB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
GDHHQS2_k127_2368056_1	1122605.KB893625_gene1664	1.325e-44	171.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF4185,Lipase_GDSL_2
GDHHQS2_k127_2368056_0	1340493.JNIF01000003_gene1814	2.446e-134	463.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2368829_1	1267535.KB906767_gene4145	4.935e-59	216.0	COG1629@1|root,COG1629@2|Bacteria,3Y2JN@57723|Acidobacteria,2JI08@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2368829_0	1379270.AUXF01000002_gene1601	2.081e-80	276.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_237541_4	306281.AJLK01000039_gene3439	4.942e-36	141.0	COG4636@1|root,COG4636@2|Bacteria,1G2JA@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_237541_1	1267535.KB906767_gene1536	2.466e-190	636.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_237541_3	1192034.CAP_2351	7.343e-59	215.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,42UCW@68525|delta/epsilon subdivisions,2WQWQ@28221|Deltaproteobacteria,2YV6G@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GDHHQS2_k127_237541_5	234267.Acid_2286	4.943e-24	110.0	COG0671@1|root,COG0671@2|Bacteria,3Y5F0@57723|Acidobacteria	57723|Acidobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS2_k127_237541_7	234267.Acid_3141	8.311e-11	69.0	COG1595@1|root,COG1595@2|Bacteria,3Y5J6@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_237541_6	1408813.AYMG01000020_gene2972	1.368e-16	90.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	2.3.1.51	ko:K00655,ko:K07451	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	DUF262,DUF968,HNH
GDHHQS2_k127_237541_2	864051.BurJ1DRAFT_0596	6.834e-70	268.0	COG0419@1|root,COG3950@1|root,COG0419@2|Bacteria,COG3950@2|Bacteria,1MUE0@1224|Proteobacteria,2WF7A@28216|Betaproteobacteria,1KMP2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_237541_0	1340493.JNIF01000004_gene599	9.624e-211	662.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_2384244_0	234267.Acid_5753	2.582e-114	389.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2384244_2	1267533.KB906736_gene1246	5.296e-52	199.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2384244_1	234267.Acid_6265	2.33e-68	244.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2386059_14	1267535.KB906767_gene4462	1.05e-17	83.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS2_k127_2386059_1	234267.Acid_5121	0.0	1121.0	COG0480@1|root,COG0480@2|Bacteria,3Y2YX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_2386059_8	234267.Acid_5122	4.21e-77	260.0	COG0049@1|root,COG0049@2|Bacteria,3Y3FF@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS2_k127_2386059_9	1267535.KB906767_gene2709	2.056e-72	244.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS2_k127_2386059_5	1519464.HY22_06315	4.488e-166	532.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS2_k127_2386059_12	1521187.JPIM01000053_gene2936	7.672e-24	114.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi,375GG@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2386059_10	234267.Acid_7894	1.683e-56	211.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
GDHHQS2_k127_2386059_0	1340493.JNIF01000003_gene3639	0.0	1294.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS2_k127_2386059_11	234267.Acid_6469	1.215e-46	175.0	COG2825@1|root,COG2825@2|Bacteria,3Y56P@57723|Acidobacteria	57723|Acidobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
GDHHQS2_k127_2386059_2	1340493.JNIF01000003_gene2993	2.926e-258	807.0	COG0442@1|root,COG0442@2|Bacteria,3Y329@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GDHHQS2_k127_2386059_7	1340493.JNIF01000003_gene2994	3.654e-95	325.0	COG0520@1|root,COG0520@2|Bacteria,3Y632@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_2386059_6	234267.Acid_0554	2.815e-109	392.0	COG1404@1|root,COG1404@2|Bacteria,3Y2EZ@57723|Acidobacteria	57723|Acidobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GDHHQS2_k127_2386059_13	1385517.N800_00455	3.745e-20	107.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GDHHQS2_k127_2386059_3	1340493.JNIF01000004_gene155	3.81e-235	762.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,He_PIG,Laminin_G_3,NHL,SGL
GDHHQS2_k127_2386059_4	886293.Sinac_5110	2.45e-181	578.0	COG3119@1|root,COG3119@2|Bacteria,2IXSN@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2386059_15	234267.Acid_6547	0.0008741	42.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2396209_1	1267535.KB906767_gene1461	1.794e-66	231.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
GDHHQS2_k127_2396209_0	903818.KI912268_gene2972	5.026e-143	482.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DoxX,Sulfatase
GDHHQS2_k127_2396209_3	391625.PPSIR1_12068	1.193e-21	96.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.17,4.3.1.19	ko:K17989	ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00590,R00996	RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2398110_0	926566.Terro_3979	1.529e-92	317.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_2404058_0	1267535.KB906767_gene844	6.832e-129	425.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria,2JHUM@204432|Acidobacteriia	204432|Acidobacteriia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS2_k127_2404058_2	1340493.JNIF01000003_gene1742	6.154e-99	330.0	COG1082@1|root,COG1082@2|Bacteria,3Y4ZI@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2404058_5	234267.Acid_1841	1.825e-28	120.0	29CGV@1|root,2ZZF9@2|Bacteria,3Y4JX@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
GDHHQS2_k127_2404058_1	234267.Acid_1840	8.608e-107	351.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
GDHHQS2_k127_2404058_3	234267.Acid_1839	2.082e-98	331.0	COG0196@1|root,COG0196@2|Bacteria,3Y34N@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS2_k127_2404058_4	234267.Acid_1436	3.697e-95	316.0	COG3684@1|root,COG3981@1|root,COG3684@2|Bacteria,COG3981@2|Bacteria,3Y33H@57723|Acidobacteria	57723|Acidobacteria	G	deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS2_k127_2405117_0	1340493.JNIF01000003_gene3117	1.473e-317	1004.0	COG1629@1|root,COG1629@2|Bacteria,3Y2N1@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2405117_3	234267.Acid_7116	8.81e-97	320.0	COG0009@1|root,COG0009@2|Bacteria,3Y43Z@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
GDHHQS2_k127_2405117_1	234267.Acid_7115	7.702e-310	958.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria	57723|Acidobacteria	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS2_k127_2405117_5	234267.Acid_4378	3.987e-42	159.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
GDHHQS2_k127_2405117_6	1267535.KB906767_gene1278	2.349e-41	160.0	COG1999@1|root,COG1999@2|Bacteria,3Y855@57723|Acidobacteria	57723|Acidobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS2_k127_2405117_2	1267535.KB906767_gene1277	1.563e-118	388.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS2_k127_2405117_4	1123257.AUFV01000007_gene336	5.472e-52	188.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1X824@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_2420551_6	234267.Acid_7387	4.636e-113	374.0	COG2755@1|root,COG2755@2|Bacteria,3Y7DX@57723|Acidobacteria	57723|Acidobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_2420551_8	1267534.KB906760_gene1372	1.075e-18	87.0	COG0236@1|root,COG0236@2|Bacteria,3Y91M@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS2_k127_2420551_7	1340493.JNIF01000003_gene2602	4.075e-85	291.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS2_k127_2420551_2	1267535.KB906767_gene3229	1.074e-197	621.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS2_k127_2420551_4	1382359.JIAL01000001_gene1553	9.774e-185	586.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS2_k127_2420551_5	1340493.JNIF01000003_gene2845	4.545e-120	398.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GDHHQS2_k127_2420551_1	1267533.KB906733_gene3215	9.806e-205	666.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2420551_3	234267.Acid_1528	4.111e-186	594.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria	2|Bacteria	P	PFAM Sulfatase	atsA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_2420551_0	1267535.KB906767_gene5437	6.707e-268	873.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,3Y2VV@57723|Acidobacteria,2JIJ7@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase D, 3'-phosphoesterase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS2_k127_2420551_9	497964.CfE428DRAFT_3782	1.202e-11	72.0	COG3119@1|root,COG5306@1|root,COG3119@2|Bacteria,COG5306@2|Bacteria,46UXB@74201|Verrucomicrobia	2|Bacteria	P	Sulfatase	-	-	3.4.14.5	ko:K01278,ko:K03561	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko04090,ko04147	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,Sulfatase
GDHHQS2_k127_2426653_0	1123508.JH636449_gene7255	4.228e-26	118.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS2_k127_2426653_1	1123248.KB893317_gene4276	1.036e-24	119.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes	976|Bacteroidetes	EU	Peptidase, S9A B C family, catalytic domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_2428039_1	1121946.AUAX01000009_gene4557	8.032e-36	141.0	COG3934@1|root,COG3934@2|Bacteria,2IC0X@201174|Actinobacteria,4DBJ0@85008|Micromonosporales	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	CBM_2,Cellulase
GDHHQS2_k127_2428039_0	497964.CfE428DRAFT_4151	7.649e-170	558.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
GDHHQS2_k127_2428039_2	234267.Acid_1068	1.275e-35	151.0	COG2264@1|root,COG2264@2|Bacteria,3Y5SG@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS2_k127_2428039_3	497964.CfE428DRAFT_5247	3.223e-10	72.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_2428140_1	1211813.CAPH01000003_gene1379	3.07e-100	337.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,2FM8Y@200643|Bacteroidia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_2428140_0	385682.AFSL01000072_gene1345	7.989e-220	693.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4N@976|Bacteroidetes,2G2S8@200643|Bacteroidia	976|Bacteroidetes	C	K00162 pyruvate dehydrogenase E1 component subunit beta	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_2437800_5	639030.JHVA01000001_gene2962	3.547e-44	163.0	COG2159@1|root,COG2159@2|Bacteria,3Y7XT@57723|Acidobacteria,2JNXE@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_2437800_3	1333998.M2A_2194	7.029e-63	222.0	COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2TSKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS2_k127_2437800_0	1340493.JNIF01000003_gene4600	1.557e-237	776.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2437800_2	497964.CfE428DRAFT_6614	2.288e-129	427.0	2BZ9C@1|root,2Z998@2|Bacteria,46S4U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_2437800_1	234267.Acid_3331	9.69e-175	560.0	COG0673@1|root,COG0673@2|Bacteria,3Y2KV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_2437800_4	1336208.JADY01000001_gene936	1.423e-60	217.0	COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_2440709_1	234267.Acid_6265	1.864e-47	176.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2440709_0	234267.Acid_3357	3.329e-135	444.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2441636_0	1267534.KB906754_gene3673	1.115e-221	702.0	28HBM@1|root,2Z7NK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2441636_1	278963.ATWD01000001_gene2919	3.205e-47	181.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2442165_3	457415.HMPREF1006_00098	7.846e-11	64.0	COG0151@1|root,COG0151@2|Bacteria,3T9U8@508458|Synergistetes	508458|Synergistetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
GDHHQS2_k127_2442165_0	401526.TcarDRAFT_0394	3.453e-42	160.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4H4GQ@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS2_k127_2442165_2	1449347.JQLN01000005_gene4651	2.655e-13	79.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,2M57W@2063|Kitasatospora	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS2_k127_2442165_4	1118054.CAGW01000005_gene3760	4.635e-09	63.0	arCOG03922@1|root,33G2Q@2|Bacteria,1W37T@1239|Firmicutes,4I0PA@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
GDHHQS2_k127_2442165_1	1227497.C491_17022	5.485e-27	115.0	COG1960@1|root,arCOG01707@2157|Archaea,2Y2UP@28890|Euryarchaeota,23ZAG@183963|Halobacteria	183963|Halobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_2449331_1	1340493.JNIF01000003_gene3549	2.848e-76	274.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2449331_2	1340493.JNIF01000003_gene3549	3.465e-22	104.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2449331_0	67275.JOAP01000049_gene770	5.898e-104	346.0	COG3964@1|root,COG3964@2|Bacteria,2IERE@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase family	dho	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_245451_2	570952.ATVH01000019_gene835	6.122e-31	126.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2U3S7@28211|Alphaproteobacteria,2JR3P@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS2_k127_245451_0	452637.Oter_2672	5.271e-96	329.0	COG2271@1|root,COG2271@2|Bacteria,46UQA@74201|Verrucomicrobia,3K8MQ@414999|Opitutae	414999|Opitutae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_245451_1	1123508.JH636448_gene7663	7.199e-67	236.0	COG1402@1|root,COG1402@2|Bacteria,2IYP1@203682|Planctomycetes	203682|Planctomycetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
GDHHQS2_k127_2459532_0	234267.Acid_0872	1.956e-64	246.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2463253_0	234267.Acid_7510	1.001e-159	519.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2463253_1	234267.Acid_0556	4.223e-86	294.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
GDHHQS2_k127_2463253_2	926566.Terro_3115	1.333e-33	142.0	COG5534@1|root,COG5534@2|Bacteria	2|Bacteria	L	Replication initiator protein	repA	-	-	-	-	-	-	-	-	-	-	-	RPA
GDHHQS2_k127_2463253_3	945713.IALB_1400	7.383e-32	144.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
GDHHQS2_k127_2463253_4	680646.RMDY18_18820	3.817e-26	126.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,PA,Peptidase_S8,SLH,fn3_5
GDHHQS2_k127_2464323_0	204669.Acid345_4118	3.488e-137	461.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2477379_10	234267.Acid_5744	3.612e-25	109.0	COG2304@1|root,COG2304@2|Bacteria,3Y6TM@57723|Acidobacteria	57723|Acidobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
GDHHQS2_k127_2477379_6	234267.Acid_5743	1.364e-102	351.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6PH@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
GDHHQS2_k127_2477379_1	234267.Acid_5743	4.364e-198	627.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6PH@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
GDHHQS2_k127_2477379_4	1340493.JNIF01000003_gene3098	6.47e-121	402.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	bacE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_2477379_2	1340493.JNIF01000003_gene3097	9.175e-160	509.0	COG0180@1|root,COG0180@2|Bacteria,3Y2VN@57723|Acidobacteria	57723|Acidobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS2_k127_2477379_3	234267.Acid_5841	1.269e-121	402.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS2_k127_2477379_5	234267.Acid_2636	2.229e-104	353.0	COG0845@1|root,COG0845@2|Bacteria,3Y43D@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS2_k127_2477379_9	234267.Acid_1394	7.467e-49	182.0	COG2442@1|root,COG2442@2|Bacteria,3Y828@57723|Acidobacteria	57723|Acidobacteria	S	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2477379_8	204669.Acid345_3764	1.245e-56	202.0	COG2193@1|root,COG2193@2|Bacteria,3Y56Z@57723|Acidobacteria,2JMWM@204432|Acidobacteriia	204432|Acidobacteriia	C	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GDHHQS2_k127_2477379_7	234267.Acid_5420	1.056e-82	284.0	COG1752@1|root,COG1752@2|Bacteria,3Y5EY@57723|Acidobacteria	57723|Acidobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GDHHQS2_k127_2477379_0	234267.Acid_2315	1.536e-255	810.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_2479210_1	1340493.JNIF01000003_gene2109	9.368e-99	327.0	COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GDHHQS2_k127_2479210_0	1340493.JNIF01000003_gene1775	1.529e-115	383.0	COG0477@1|root,COG2814@2|Bacteria,3Y4T2@57723|Acidobacteria	57723|Acidobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_2479210_2	1267535.KB906767_gene3552	1.097e-28	121.0	COG2318@1|root,COG2318@2|Bacteria,3Y7YH@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_2479210_3	234267.Acid_5858	2.925e-23	105.0	COG0500@1|root,COG0500@2|Bacteria,3Y94A@57723|Acidobacteria	57723|Acidobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2485632_2	1198114.AciX9_0574	1.406e-35	142.0	COG0500@1|root,COG2226@2|Bacteria,3Y58M@57723|Acidobacteria,2JJRE@204432|Acidobacteriia	204432|Acidobacteriia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_2485632_1	234267.Acid_6627	8.781e-89	303.0	COG0500@1|root,COG2226@2|Bacteria,3Y46W@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_2485632_0	1267535.KB906767_gene1708	5.439e-221	696.0	COG1032@1|root,COG1032@2|Bacteria,3Y2V1@57723|Acidobacteria,2JKBR@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS2_k127_2485632_3	234267.Acid_6629	6.971e-21	97.0	COG0500@1|root,COG2226@2|Bacteria,3Y89Z@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_2489992_5	234267.Acid_6536	5.622e-47	170.0	COG3618@1|root,COG3618@2|Bacteria,3Y68G@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_2489992_4	1267535.KB906767_gene190	1.019e-63	226.0	COG3571@1|root,COG3571@2|Bacteria,3Y7N8@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_5,Abhydrolase_6
GDHHQS2_k127_2489992_0	234267.Acid_4555	4.662e-119	403.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_4555|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2489992_3	234267.Acid_0816	9.853e-83	284.0	COG0697@1|root,COG0697@2|Bacteria,3Y4NT@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_2489992_2	1340493.JNIF01000003_gene3920	3.54e-104	341.0	COG1793@1|root,COG1793@2|Bacteria,3Y6QD@57723|Acidobacteria	57723|Acidobacteria	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_2489992_1	234267.Acid_1912	3.631e-115	379.0	COG0123@1|root,COG0123@2|Bacteria,3Y70W@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_2489992_8	234267.Acid_4671	1.338e-10	70.0	2DGG8@1|root,2ZVV7@2|Bacteria,3Y8SU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2489992_6	401053.AciPR4_0208	1.167e-45	177.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2500886_2	1340493.JNIF01000003_gene3294	2.114e-24	106.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS2_k127_2500886_0	1340493.JNIF01000003_gene3295	4.869e-167	537.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
GDHHQS2_k127_2500886_1	1340493.JNIF01000003_gene3296	2.474e-118	392.0	COG4963@1|root,COG4963@2|Bacteria,3Y44H@57723|Acidobacteria	57723|Acidobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GDHHQS2_k127_2500886_3	1340493.JNIF01000003_gene3297	0.000601	43.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS2_k127_2500902_0	234267.Acid_2439	4.716e-88	301.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS2_k127_2500902_1	1340493.JNIF01000003_gene2581	3.27e-38	152.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
GDHHQS2_k127_2503498_7	880073.Calab_3447	6.45e-06	52.0	COG1373@1|root,COG1373@2|Bacteria,2NP9F@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_2503498_3	861299.J421_5839	1.667e-67	254.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_2503498_8	530564.Psta_3242	7.165e-05	55.0	COG2319@1|root,COG2319@2|Bacteria,2IXQD@203682|Planctomycetes	203682|Planctomycetes	C	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
GDHHQS2_k127_2503498_4	1123248.KB893336_gene2833	7.268e-62	232.0	COG3391@1|root,COG3391@2|Bacteria,4NHHU@976|Bacteroidetes,1IW3W@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2503498_2	1123242.JH636435_gene2134	4.558e-119	398.0	COG1914@1|root,COG1914@2|Bacteria,2IYEM@203682|Planctomycetes	2|Bacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2503498_1	234267.Acid_0729	1.368e-162	535.0	COG1538@1|root,COG1538@2|Bacteria,3Y6AC@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_2503498_0	234267.Acid_0730	6.828e-225	719.0	COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_2503498_6	987059.RBXJA2T_10119	2.29e-33	140.0	COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1PGX6@1224|Proteobacteria,2W865@28216|Betaproteobacteria,1KNRA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS2_k127_2507667_1	278963.ATWD01000001_gene4176	1.366e-93	319.0	COG1629@1|root,COG4771@2|Bacteria,3Y3NM@57723|Acidobacteria,2JI5I@204432|Acidobacteriia	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2507667_0	1340493.JNIF01000003_gene3478	5.584e-148	506.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2507667_2	1123242.JH636435_gene2126	7.719e-62	224.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2517861_0	1340493.JNIF01000003_gene4600	2.991e-75	273.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2519549_3	886293.Sinac_6746	3.834e-63	225.0	COG3356@1|root,COG3356@2|Bacteria,2IXB9@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_2519549_1	1340493.JNIF01000004_gene422	2.311e-129	422.0	COG2130@1|root,COG2130@2|Bacteria	2|Bacteria	S	13-prostaglandin reductase activity	yfmJ	-	1.6.5.5	ko:K00344,ko:K07119	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N_2,ADH_zinc_N
GDHHQS2_k127_2519549_0	243090.RB12559	3.165e-134	439.0	COG1820@1|root,COG1820@2|Bacteria,2IXMH@203682|Planctomycetes	203682|Planctomycetes	G	Amidohydrolase family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_2519549_2	234267.Acid_1383	3.466e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,3Y4WX@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.175	ko:K00059,ko:K22185	ko00040,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00040,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R01429,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2519549_4	1123023.JIAI01000002_gene5873	5.787e-13	73.0	COG1028@1|root,COG1028@2|Bacteria,2GKG7@201174|Actinobacteria,4E9KY@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_252224_1	234267.Acid_0974	2.278e-215	686.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_252224_0	234267.Acid_0975	2.76e-257	805.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Sulfatase
GDHHQS2_k127_2524957_3	158190.SpiGrapes_2538	4.507e-38	152.0	COG1864@1|root,COG1864@2|Bacteria,2J7IP@203691|Spirochaetes	203691|Spirochaetes	V	DNA RNA non-specific endonuclease	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_2524957_4	204669.Acid345_4391	2.36e-25	107.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2524957_1	1267533.KB906736_gene1246	4.059e-166	553.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_2524957_0	1267535.KB906767_gene3954	2.224e-261	813.0	COG4799@1|root,COG4799@2|Bacteria,3Y3DC@57723|Acidobacteria,2JIP2@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS2_k127_2524957_2	234267.Acid_3874	5.651e-97	329.0	COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria	57723|Acidobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS2_k127_2531892_2	1123256.KB907931_gene2787	5.439e-07	53.0	COG2960@1|root,COG2960@2|Bacteria,1R494@1224|Proteobacteria,1T00E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_2531892_0	378806.STAUR_4286	9.2e-103	356.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_2531892_3	7227.FBpp0291294	0.0002795	52.0	COG4886@1|root,KOG4194@2759|Eukaryota,39JK1@33154|Opisthokonta,3BDMH@33208|Metazoa,3CSI3@33213|Bilateria,41TZV@6656|Arthropoda,3SK9Q@50557|Insecta,44ZNC@7147|Diptera,45XAD@7214|Drosophilidae	33208|Metazoa	T	Leucine rich repeat N-terminal domain	LRIG3	GO:0003008,GO:0003674,GO:0005102,GO:0005114,GO:0005126,GO:0005160,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007399,GO:0007423,GO:0007600,GO:0007605,GO:0008150,GO:0009653,GO:0009719,GO:0009790,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010453,GO:0010470,GO:0010605,GO:0010640,GO:0010646,GO:0010647,GO:0010721,GO:0010975,GO:0010977,GO:0016020,GO:0016021,GO:0017015,GO:0019222,GO:0021675,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030162,GO:0030334,GO:0030424,GO:0030426,GO:0030427,GO:0030511,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031344,GO:0031345,GO:0031982,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032474,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033267,GO:0034713,GO:0036477,GO:0040008,GO:0040012,GO:0040014,GO:0040018,GO:0042176,GO:0042177,GO:0042221,GO:0042303,GO:0042471,GO:0042472,GO:0042633,GO:0042659,GO:0042661,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043583,GO:0044297,GO:0044424,GO:0044425,GO:0044459,GO:0044463,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045861,GO:0045927,GO:0045995,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048638,GO:0048639,GO:0048679,GO:0048681,GO:0048699,GO:0048731,GO:0048839,GO:0048840,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050954,GO:0051043,GO:0051045,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051716,GO:0051960,GO:0051961,GO:0060255,GO:0060284,GO:0060341,GO:0060384,GO:0065007,GO:0070570,GO:0070571,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090092,GO:0090100,GO:0090287,GO:0090596,GO:0097458,GO:0097708,GO:0120025,GO:0120035,GO:0120038,GO:0150034,GO:1903034,GO:1903035,GO:1903827,GO:1903829,GO:1903844,GO:1903846,GO:1905770,GO:1905902,GO:2000008,GO:2000010,GO:2000026,GO:2000027,GO:2000145,GO:2000380,GO:2001222	-	-	-	-	-	-	-	-	-	-	I-set,LRRCT,LRRNT,LRR_8
GDHHQS2_k127_2531892_1	3750.XP_008341523.1	2.417e-19	102.0	2CNBU@1|root,2QV2U@2759|Eukaryota,37T4I@33090|Viridiplantae,3GFEA@35493|Streptophyta,4JHQS@91835|fabids	35493|Streptophyta	S	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,LRR_8
GDHHQS2_k127_2532401_3	1123508.JH636439_gene1117	4.603e-64	226.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_2532401_1	344747.PM8797T_27150	4.781e-79	281.0	COG4409@1|root,COG4409@2|Bacteria,2J4T9@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_2532401_2	234267.Acid_2168	2.239e-66	235.0	COG0457@1|root,COG0457@2|Bacteria,3Y7RX@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2532401_0	234267.Acid_2169	3.417e-121	412.0	2EZ67@1|root,33SC9@2|Bacteria,3Y6G7@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2532401_4	246969.TAM4_499	2.131e-08	60.0	COG0515@1|root,arCOG00372@1|root,arCOG03264@1|root,arCOG00372@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2XWYZ@28890|Euryarchaeota,2437Z@183968|Thermococci	183968|Thermococci	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_2532859_12	489825.LYNGBM3L_52710	5.329e-05	50.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
GDHHQS2_k127_2532859_9	1192034.CAP_7045	3.429e-43	181.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2532859_6	234267.Acid_5255	8.614e-70	246.0	2B11W@1|root,31TFA@2|Bacteria,3Y4Z8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2532859_8	1267535.KB906767_gene4511	8.548e-48	192.0	COG3637@1|root,COG3637@2|Bacteria,3Y783@57723|Acidobacteria	57723|Acidobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
GDHHQS2_k127_2532859_0	1340493.JNIF01000003_gene3494	7.823e-205	664.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
GDHHQS2_k127_2532859_1	234267.Acid_7682	1.28e-154	496.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
GDHHQS2_k127_2532859_7	1340493.JNIF01000003_gene2268	1.603e-57	214.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2532859_11	1536775.H70737_07345	1.089e-07	62.0	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,274UW@186822|Paenibacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_2532859_3	1267535.KB906767_gene443	8.915e-87	292.0	COG1738@1|root,COG1738@2|Bacteria,3Y35H@57723|Acidobacteria,2JIRA@204432|Acidobacteriia	204432|Acidobacteriia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
GDHHQS2_k127_2532859_2	517418.Ctha_1616	1.303e-121	399.0	COG1858@1|root,COG1858@2|Bacteria,1FDVA@1090|Chlorobi	1090|Chlorobi	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_2532859_10	1449350.OCH239_01385	1.374e-16	82.0	2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
GDHHQS2_k127_2532859_4	234267.Acid_3676	1.75e-86	288.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS2_k127_2532859_5	1267535.KB906767_gene5195	6.49e-83	277.0	COG2407@1|root,COG2407@2|Bacteria,3Y63P@57723|Acidobacteria	57723|Acidobacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2534682_1	1123508.JH636439_gene662	6.329e-43	168.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
GDHHQS2_k127_2534682_0	697281.Mahau_2710	8.831e-59	219.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,42GM3@68295|Thermoanaerobacterales	186801|Clostridia	S	Conserved hypothetical protein 698	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
GDHHQS2_k127_2534682_2	1210884.HG799475_gene15282	2.135e-30	124.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_2539806_0	886293.Sinac_6485	1.012e-188	599.0	COG0613@1|root,COG0613@2|Bacteria,2IY27@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2539806_1	243090.RB107	2.824e-175	560.0	COG1520@1|root,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_2539806_2	768671.ThimaDRAFT_4283	4.705e-14	73.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1S9WR@1236|Gammaproteobacteria,1WZ13@135613|Chromatiales	135613|Chromatiales	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS2_k127_2545970_7	1340493.JNIF01000003_gene2166	7.812e-56	213.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2545970_5	234267.Acid_4993	7.601e-74	253.0	COG0461@1|root,COG0461@2|Bacteria	2|Bacteria	F	orotate phosphoribosyltransferase activity	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_2545970_4	1340493.JNIF01000003_gene4132	8.581e-86	293.0	COG0101@1|root,COG0101@2|Bacteria,3Y2MS@57723|Acidobacteria	57723|Acidobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS2_k127_2545970_8	378806.STAUR_4977	9.991e-27	122.0	COG2304@1|root,COG2374@1|root,COG2304@2|Bacteria,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,42XZM@68525|delta/epsilon subdivisions,2WT9C@28221|Deltaproteobacteria,2Z13B@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
GDHHQS2_k127_2545970_6	1267535.KB906767_gene1459	1.027e-57	202.0	COG0633@1|root,COG0633@2|Bacteria,3Y4T7@57723|Acidobacteria,2JJFT@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
GDHHQS2_k127_2545970_3	234267.Acid_7533	7.331e-90	304.0	COG3622@1|root,COG3622@2|Bacteria,3Y5NQ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_2545970_0	204669.Acid345_3939	8.077e-248	780.0	COG0531@1|root,COG0531@2|Bacteria,3Y356@57723|Acidobacteria,2JP5J@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2545970_1	1403819.BATR01000180_gene6025	7.031e-128	417.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_2545970_2	1340493.JNIF01000003_gene2185	8.576e-94	310.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria	57723|Acidobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2551019_0	1267533.KB906742_gene676	1.76e-118	414.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria,2JM2J@204432|Acidobacteriia	204432|Acidobacteriia	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
GDHHQS2_k127_2558006_1	1340493.JNIF01000003_gene1966	9.361e-246	765.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2558006_0	234267.Acid_6290	0.0	1179.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2566931_0	234267.Acid_3771	9.472e-142	459.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2566931_1	234267.Acid_5940	3.674e-40	162.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2566931_2	234267.Acid_6265	6.604e-30	129.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_256875_0	234267.Acid_5518	2.066e-148	478.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_256875_2	1340493.JNIF01000003_gene3144	1.651e-105	353.0	COG0845@1|root,COG0845@2|Bacteria,3Y3S2@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_256875_5	641524.ADICYQ_5316	2.311e-09	61.0	COG1957@1|root,COG1957@2|Bacteria,4NH09@976|Bacteroidetes,47JEE@768503|Cytophagia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
GDHHQS2_k127_256875_4	234267.Acid_2633	2.157e-13	74.0	COG1957@1|root,COG1957@2|Bacteria,3Y6U8@57723|Acidobacteria	57723|Acidobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
GDHHQS2_k127_256875_1	497964.CfE428DRAFT_3506	8.3e-138	449.0	COG4409@1|root,COG4409@2|Bacteria,46SHF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_256875_3	1340493.JNIF01000003_gene2370	1.417e-21	95.0	COG3597@1|root,COG3597@2|Bacteria,3Y7Z9@57723|Acidobacteria	57723|Acidobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2572701_2	240015.ACP_0965	8.684e-09	56.0	COG0745@1|root,COG0745@2|Bacteria,3Y53N@57723|Acidobacteria,2JN7U@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_2572701_1	278963.ATWD01000002_gene332	1.025e-19	96.0	2CEWK@1|root,33BBP@2|Bacteria,3Y5YV@57723|Acidobacteria,2JNQP@204432|Acidobacteriia	204432|Acidobacteriia	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
GDHHQS2_k127_2572701_0	234267.Acid_5374	4.831e-140	452.0	COG2201@1|root,COG2201@2|Bacteria,3Y35K@57723|Acidobacteria	57723|Acidobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS2_k127_2580539_7	1071085.KK033114_gene1568	0.0003498	50.0	COG0457@1|root,arCOG03032@2157|Archaea,2Y7M7@28890|Euryarchaeota,23TJM@183963|Halobacteria	183963|Halobacteria	S	COG0457 FOG TPR repeat	tpr	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_2580539_0	401053.AciPR4_2763	2.619e-319	1010.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria,2JKDK@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2580539_6	706587.Desti_3257	5.394e-82	291.0	COG2856@1|root,COG2856@2|Bacteria,1R5HK@1224|Proteobacteria,42ZGN@68525|delta/epsilon subdivisions,2WV2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
GDHHQS2_k127_2580539_3	204669.Acid345_1052	7.064e-119	413.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS2_k127_2580539_1	234267.Acid_0030	1.153e-281	902.0	COG1074@1|root,COG1074@2|Bacteria,3Y41J@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS2_k127_2580539_2	234267.Acid_0029	4.399e-221	721.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	addB	-	3.6.4.12,5.99.1.2	ko:K03169,ko:K16899	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PDDEXK_1
GDHHQS2_k127_2580539_5	1192034.CAP_4787	4.067e-99	336.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_2580539_4	237368.SCABRO_03044	1.275e-107	361.0	COG2204@1|root,COG2204@2|Bacteria,2IXIQ@203682|Planctomycetes	203682|Planctomycetes	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2590562_1	1340493.JNIF01000003_gene4558	1.363e-92	310.0	COG1082@1|root,COG1082@2|Bacteria,3Y3CH@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2590562_0	234267.Acid_7167	5.761e-235	743.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
GDHHQS2_k127_2601417_3	504472.Slin_0438	4.666e-40	158.0	COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,47KUI@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_2601417_0	1340493.JNIF01000003_gene3810	3.694e-97	327.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2601417_4	234267.Acid_6341	1.047e-38	147.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_2601417_1	1267535.KB906767_gene2656	3.248e-82	276.0	COG1898@1|root,COG1898@2|Bacteria,3Y5V0@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS2_k127_2601417_2	234267.Acid_4352	9.874e-65	226.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
GDHHQS2_k127_2602722_0	1340493.JNIF01000003_gene4600	4.708e-102	353.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2614288_3	240015.ACP_1549	5.281e-08	59.0	2DQEG@1|root,336BD@2|Bacteria,3Y4BP@57723|Acidobacteria,2JJZF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2614288_0	234267.Acid_5551	6.336e-125	409.0	COG4975@1|root,COG4975@2|Bacteria,3Y7IY@57723|Acidobacteria	57723|Acidobacteria	G	Glucose uptake	-	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	-
GDHHQS2_k127_2614288_1	1267535.KB906767_gene3825	2.73e-124	431.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2614288_2	639030.JHVA01000001_gene2752	3.175e-114	378.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria,2JKDV@204432|Acidobacteriia	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2615626_3	639030.JHVA01000001_gene590	1.124e-50	188.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2615626_1	1123242.JH636434_gene3703	2.082e-120	409.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2615626_4	349124.Hhal_1783	0.0002769	49.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1WXRD@135613|Chromatiales	135613|Chromatiales	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
GDHHQS2_k127_2615626_0	1267535.KB906767_gene1802	1.672e-222	702.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria,2JKQY@204432|Acidobacteriia	204432|Acidobacteriia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
GDHHQS2_k127_2615626_2	234267.Acid_5981	1.424e-95	318.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2617476_3	595537.Varpa_4198	2.876e-24	111.0	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,2VXT1@28216|Betaproteobacteria,4AHM4@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_2617476_2	1278073.MYSTI_04650	5.258e-28	118.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2617476_4	1313172.YM304_22880	9.108e-10	72.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,RCC1,RCC1_2,fn3
GDHHQS2_k127_2617476_0	1267535.KB906767_gene4131	6.487e-236	741.0	COG2303@1|root,COG2303@2|Bacteria,3Y41Y@57723|Acidobacteria,2JIXF@204432|Acidobacteriia	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_262028_3	1340493.JNIF01000003_gene4160	1.624e-137	469.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_262028_2	234267.Acid_7658	1.019e-235	736.0	COG1953@1|root,COG1953@2|Bacteria,3Y2FU@57723|Acidobacteria	57723|Acidobacteria	FH	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GDHHQS2_k127_262028_1	234267.Acid_7659	1.071e-245	764.0	COG0044@1|root,COG0044@2|Bacteria,3Y48H@57723|Acidobacteria	57723|Acidobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GDHHQS2_k127_262028_4	1340493.JNIF01000003_gene1485	7.843e-62	216.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_262028_0	269799.Gmet_3489	6.278e-316	984.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42ZB2@68525|delta/epsilon subdivisions,2WUMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
GDHHQS2_k127_262028_5	234267.Acid_7400	6.211e-20	99.0	COG2318@1|root,COG2318@2|Bacteria,3Y8J8@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_2627277_0	1340493.JNIF01000003_gene3842	6.4e-323	1009.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2627277_1	1340493.JNIF01000003_gene3843	4.157e-235	737.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2627277_2	1340493.JNIF01000003_gene2650	1.604e-110	387.0	COG1629@1|root,COG4771@2|Bacteria,3Y980@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2630608_1	234267.Acid_5940	1.057e-29	131.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2630608_2	1162668.LFE_2212	4.632e-14	76.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5	-	-	DDE_Tnp_ISAZ013,Peripla_BP_3
GDHHQS2_k127_2630608_0	401053.AciPR4_1439	3.665e-61	220.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2630987_0	234267.Acid_0755	4.843e-164	520.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria	57723|Acidobacteria	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
GDHHQS2_k127_2630987_1	926550.CLDAP_17740	2.863e-40	158.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	paiA	-	2.3.1.128,2.3.1.183,2.7.6.3	ko:K00950,ko:K03789,ko:K03823	ko00440,ko00790,ko01100,ko01130,map00440,map00790,map01100,map01130	M00126,M00841	R03503,R08871,R08938	RC00002,RC00004,RC00017,RC00064	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_263861_1	414684.RC1_3878	1.792e-25	114.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2TRH8@28211|Alphaproteobacteria,2JQ72@204441|Rhodospirillales	204441|Rhodospirillales	NT	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
GDHHQS2_k127_263861_0	497964.CfE428DRAFT_0675	2.67e-63	236.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,46U7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA
GDHHQS2_k127_2639552_0	1267535.KB906767_gene1795	1.274e-214	700.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2639634_3	395965.Msil_2404	1.482e-15	84.0	2DYN7@1|root,34AEC@2|Bacteria,1N2HW@1224|Proteobacteria,2UEIS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2639634_2	1267535.KB906767_gene1639	2.85e-210	692.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2639634_1	1340493.JNIF01000004_gene772	2.01e-245	764.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2639634_0	1340493.JNIF01000003_gene3464	2.441e-291	930.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_264202_4	929703.KE386491_gene2093	1.351e-71	248.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_264202_2	234267.Acid_7517	4.071e-150	495.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_264202_3	234267.Acid_7517	4.031e-105	353.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_264202_0	234267.Acid_0223	4.886e-227	745.0	COG3523@1|root,COG3523@2|Bacteria,3Y3IQ@57723|Acidobacteria	57723|Acidobacteria	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
GDHHQS2_k127_264202_5	1267535.KB906767_gene1598	2.255e-63	225.0	COG3455@1|root,COG3455@2|Bacteria,3Y4ZZ@57723|Acidobacteria,2JN1G@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Type IV VI secretion system, DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
GDHHQS2_k127_264202_1	234267.Acid_0225	4.415e-170	548.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZI@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
GDHHQS2_k127_264202_6	1267535.KB906767_gene1596	4.518e-08	64.0	2A0FS@1|root,30NJK@2|Bacteria,3Y8KG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2644227_0	1340493.JNIF01000004_gene88	3.295e-274	880.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2644227_4	1278073.MYSTI_02198	7.671e-05	46.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,CHB_HEX_C_1,Glucosaminidase,Glyco_hydro_25,Peptidase_M57,Polysacc_deac_1,YkuD
GDHHQS2_k127_2644227_2	1340493.JNIF01000003_gene3435	1.275e-62	228.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_2644227_1	1340493.JNIF01000003_gene3118	8.153e-158	537.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
GDHHQS2_k127_2644227_3	472759.Nhal_0320	1.002e-27	115.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,1S75C@1236|Gammaproteobacteria,1X1JV@135613|Chromatiales	135613|Chromatiales	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_2648222_1	234267.Acid_1642	5.724e-159	539.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1642|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2648222_2	639030.JHVA01000001_gene1888	5.964e-101	349.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	betC	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,DUF4976,Sulfatase
GDHHQS2_k127_2648222_0	575540.Isop_3370	3.004e-179	575.0	COG3386@1|root,COG3386@2|Bacteria,2J2MK@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
GDHHQS2_k127_2648222_3	234267.Acid_0199	1.424e-88	299.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	hpcH	-	2.7.7.38,4.1.2.20,4.1.2.52	ko:K00979,ko:K01630,ko:K02510	ko00053,ko00350,ko00540,ko01100,ko01120,map00053,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R02754,R03277,R03351,R11396	RC00152,RC00307,RC00435,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
GDHHQS2_k127_2650542_0	234267.Acid_1455	5.756e-125	410.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria	57723|Acidobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
GDHHQS2_k127_2650542_3	234267.Acid_1454	2.372e-75	265.0	COG1651@1|root,COG1651@2|Bacteria,3Y2G9@57723|Acidobacteria	57723|Acidobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DsbC_N,Thioredoxin_4
GDHHQS2_k127_2650542_2	1340493.JNIF01000003_gene4083	5.568e-83	298.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria	57723|Acidobacteria	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS2_k127_2650542_1	1340493.JNIF01000003_gene4084	6.837e-85	291.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS2_k127_2650542_4	234267.Acid_3962	1.785e-70	246.0	COG1028@1|root,COG1028@2|Bacteria,3Y7MJ@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2651216_1	204669.Acid345_1889	1.528e-68	236.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria,2JP53@204432|Acidobacteriia	204432|Acidobacteriia	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2651216_0	608538.HTH_0199	1.12e-199	630.0	COG0422@1|root,COG0422@2|Bacteria,2G3RS@200783|Aquificae	200783|Aquificae	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
GDHHQS2_k127_2653198_4	1089550.ATTH01000001_gene183	1.069e-35	147.0	COG0438@1|root,COG0438@2|Bacteria,4NKNS@976|Bacteroidetes,1FK33@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2653198_1	351607.Acel_0449	9.657e-141	460.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4ERDN@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_2653198_3	671143.DAMO_0912	9.904e-127	413.0	COG0451@1|root,COG0451@2|Bacteria,2NPS7@2323|unclassified Bacteria	2|Bacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS2_k127_2653198_2	234267.Acid_4658	1.167e-132	438.0	COG0472@1|root,COG0472@2|Bacteria,3Y5GB@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS2_k127_2653198_5	879212.DespoDRAFT_03367	6.391e-31	137.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2MIM4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A core-O-antigen ligase-like enyme	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
GDHHQS2_k127_2653198_0	234267.Acid_2813	5.733e-237	758.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2654493_1	171693.BN988_01982	7.488e-180	582.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,4ICAZ@91061|Bacilli,23K8G@182709|Oceanobacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2654493_0	234267.Acid_5624	9.202e-200	634.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,3Y2X1@57723|Acidobacteria	57723|Acidobacteria	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
GDHHQS2_k127_2660562_0	1267535.KB906767_gene3187	4.867e-321	1006.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CarbopepD_reg_2,Plug
GDHHQS2_k127_2660562_1	1267535.KB906767_gene217	2.462e-51	193.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_2660562_2	69395.JQLZ01000006_gene2054	2.084e-25	114.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_2668362_2	234267.Acid_3375	1.447e-15	81.0	COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria	57723|Acidobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS2_k127_2668362_1	1340493.JNIF01000003_gene4181	3.597e-93	316.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_2668362_0	886293.Sinac_5109	7.115e-235	748.0	COG2010@1|root,COG2010@2|Bacteria,2IXIG@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2676243_2	388051.AUFE01000037_gene3140	2.717e-11	66.0	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,2VKX0@28216|Betaproteobacteria,1K3B9@119060|Burkholderiaceae	28216|Betaproteobacteria	P	amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
GDHHQS2_k127_2676243_0	1108045.GORHZ_053_00100	3.895e-80	278.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4GAQ8@85026|Gordoniaceae	201174|Actinobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,4.1.3.32	ko:K03417,ko:K20454	ko00640,ko00760,ko01120,map00640,map00760,map01120	-	R00409,R01355	RC00286,RC00287,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
GDHHQS2_k127_2676243_1	439481.Aboo_1465	3.235e-37	143.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,3F2QD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GDHHQS2_k127_268525_1	1340493.JNIF01000004_gene277	4.222e-51	190.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_268525_0	1340493.JNIF01000004_gene278	8.036e-282	874.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PD40,PSCyt1,PSCyt2,PSD1,WD40
GDHHQS2_k127_2686186_2	1267535.KB906767_gene4236	2.87e-32	132.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_2686186_0	234267.Acid_1724	8.558e-79	288.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2686186_1	240015.ACP_2007	9.378e-69	241.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2686363_1	1210884.HG799463_gene9569	1.232e-68	241.0	COG3356@1|root,COG3356@2|Bacteria,2IXKA@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_2686363_0	234267.Acid_5289	2.074e-109	357.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria	57723|Acidobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS2_k127_2686397_1	1267535.KB906767_gene2015	1.328e-31	124.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
GDHHQS2_k127_2686397_3	443143.GM18_2364	1.697e-07	60.0	COG3322@1|root,COG3322@2|Bacteria,1REX0@1224|Proteobacteria	1224|Proteobacteria	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2686397_0	1267535.KB906767_gene218	1.832e-147	484.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2686397_2	639030.JHVA01000001_gene91	2.164e-28	131.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_2686411_14	96561.Dole_3153	5.993e-11	64.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
GDHHQS2_k127_2686411_9	1340493.JNIF01000003_gene4628	2.771e-68	238.0	COG0225@1|root,COG0225@2|Bacteria,3Y33X@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS2_k127_2686411_6	1340493.JNIF01000003_gene4449	1.365e-109	361.0	COG1692@1|root,COG1692@2|Bacteria	2|Bacteria	S	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
GDHHQS2_k127_2686411_5	234267.Acid_4725	8.844e-121	395.0	COG0709@1|root,COG0709@2|Bacteria,3Y6V3@57723|Acidobacteria	57723|Acidobacteria	E	AIR synthase related protein, C-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_2686411_7	1267535.KB906767_gene1125	1.464e-83	284.0	COG0284@1|root,COG0284@2|Bacteria,3Y2XD@57723|Acidobacteria,2JIQY@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS2_k127_2686411_10	401053.AciPR4_1244	5.759e-52	200.0	COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_2686411_0	234267.Acid_6378	0.0	1076.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria	57723|Acidobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS2_k127_2686411_13	1340493.JNIF01000003_gene2781	4.264e-27	121.0	COG5495@1|root,COG5495@2|Bacteria,3Y57G@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GDHHQS2_k127_2686411_15	76114.ebA2500	1.973e-09	65.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,2VVBU@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS2_k127_2686411_4	1123269.NX02_15530	2.557e-130	435.0	COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,2TUZF@28211|Alphaproteobacteria,2K92K@204457|Sphingomonadales	204457|Sphingomonadales	C	Quinohemoprotein amine dehydrogenase, alpha subunit domain IV	-	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
GDHHQS2_k127_2686411_2	1522072.IL54_4168	8.779e-162	524.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria,2K8ZR@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GDHHQS2_k127_2686411_12	983920.Y88_1295	1.979e-43	161.0	2BBG1@1|root,324ZB@2|Bacteria,1RHTK@1224|Proteobacteria,2UBDA@28211|Alphaproteobacteria,2KE2W@204457|Sphingomonadales	204457|Sphingomonadales	S	Quinohemoprotein amine dehydrogenase, gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	QH-AmDH_gamma
GDHHQS2_k127_2686411_11	1192759.AKIB01000006_gene7	1.301e-48	187.0	COG3391@1|root,COG3391@2|Bacteria,1PKJM@1224|Proteobacteria,2UZ8W@28211|Alphaproteobacteria,2K2M2@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2686411_3	13690.CP98_00353	1.203e-145	479.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TUYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_2686411_18	1121918.ARWE01000001_gene177	1.86e-06	57.0	COG1404@1|root,COG1404@2|Bacteria,1PHH2@1224|Proteobacteria,42RQN@68525|delta/epsilon subdivisions,2WNZ5@28221|Deltaproteobacteria,43U27@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS2_k127_2686411_8	886293.Sinac_0689	4.77e-70	241.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS2_k127_2686411_1	1340493.JNIF01000003_gene3081	3.87e-197	617.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GDHHQS2_k127_2686411_17	1207076.ALAT01000046_gene3448	1.153e-08	63.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,1TBCN@1236|Gammaproteobacteria,1Z37I@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS2_k127_2686411_16	1340493.JNIF01000004_gene1092	4.96e-09	60.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	phlE	-	-	ko:K02511,ko:K02575,ko:K13021	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.14.3,2.A.1.14.9,2.A.1.8	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_2701258_4	1123508.JH636448_gene7593	1.032e-174	573.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2701258_3	234267.Acid_1515	2.978e-181	589.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2701258_2	234267.Acid_1514	7.068e-197	634.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2701258_5	234267.Acid_1009	5.293e-154	506.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria	57723|Acidobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS2_k127_2701258_1	234267.Acid_1008	4.772e-220	696.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria	57723|Acidobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_2701258_6	234267.Acid_0967	1.438e-110	366.0	COG0179@1|root,COG0179@2|Bacteria,3Y6BP@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
GDHHQS2_k127_2701258_0	234267.Acid_0968	4.735e-250	777.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_2701258_8	234267.Acid_0971	7.899e-51	186.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS2_k127_2701258_7	234267.Acid_0972	2.26e-69	243.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2701258_9	234267.Acid_0973	1.364e-48	184.0	COG1512@1|root,COG1512@2|Bacteria,3Y4JT@57723|Acidobacteria	57723|Acidobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GDHHQS2_k127_270542_1	234267.Acid_5181	1.36e-22	104.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GDHHQS2_k127_270542_0	234267.Acid_5180	2.125e-119	389.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
GDHHQS2_k127_2709867_11	1340493.JNIF01000003_gene3720	9.017e-93	311.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_2709867_23	420662.Mpe_A0045	1.226e-36	144.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria,2VT7F@28216|Betaproteobacteria,1KM5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS2_k127_2709867_19	1476583.DEIPH_ctg046orf0009	6.585e-48	183.0	COG0329@1|root,COG0329@2|Bacteria,1WIBA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
GDHHQS2_k127_2709867_21	42565.FP66_03085	8.59e-41	162.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XMYK@135619|Oceanospirillales	135619|Oceanospirillales	S	Deacylase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.125	ko:K15784	ko00260,ko01100,map00260,map01100	-	R09801	RC00064,RC00300	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
GDHHQS2_k127_2709867_15	485917.Phep_3577	4.228e-72	258.0	COG4409@1|root,COG4409@2|Bacteria,4NJNK@976|Bacteroidetes,1IWRN@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_2709867_17	485917.Phep_3574	7.153e-69	247.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2709867_22	189425.PGRAT_15080	8.078e-37	149.0	COG1028@1|root,COG1028@2|Bacteria,1TSPJ@1239|Firmicutes,4HCGT@91061|Bacilli,26VZM@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2709867_26	65093.PCC7418_1670	1.39e-05	52.0	2E3TC@1|root,32YQV@2|Bacteria,1G8Z7@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR Helix-turn-helix protein, CopG family protein	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
GDHHQS2_k127_2709867_5	1340493.JNIF01000003_gene2254	4.667e-177	567.0	COG1181@1|root,COG1181@2|Bacteria,3Y9AM@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
GDHHQS2_k127_2709867_6	1403819.BATR01000053_gene1609	1.614e-163	529.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IUAA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2709867_25	1385517.N800_00455	4.621e-31	143.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GDHHQS2_k127_2709867_9	1444711.CCJF01000005_gene546	1.948e-128	446.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
GDHHQS2_k127_2709867_18	234267.Acid_3837	8.756e-67	248.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
GDHHQS2_k127_2709867_8	1340493.JNIF01000003_gene1969	1.063e-144	464.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria	57723|Acidobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2709867_14	1267535.KB906767_gene4013	2.539e-78	270.0	COG2382@1|root,COG2382@2|Bacteria,3Y9FB@57723|Acidobacteria,2JP13@204432|Acidobacteriia	204432|Acidobacteriia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_2709867_16	1232410.KI421421_gene3323	8.059e-71	261.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,42P68@68525|delta/epsilon subdivisions,2WMKD@28221|Deltaproteobacteria,43V6H@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS2_k127_2709867_12	234267.Acid_1035	5.486e-89	301.0	COG0463@1|root,COG0463@2|Bacteria,3Y982@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2709867_3	1267535.KB906767_gene361	9.783e-181	576.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Q3@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_2709867_7	234267.Acid_3978	4.561e-155	502.0	COG2271@1|root,COG2271@2|Bacteria,3Y638@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2709867_0	1267535.KB906767_gene842	1.105e-210	661.0	COG0448@1|root,COG0448@2|Bacteria,3Y35M@57723|Acidobacteria,2JIZF@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_2709867_10	234267.Acid_2439	1.18e-96	322.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS2_k127_2709867_1	234267.Acid_2438	1.323e-201	635.0	COG0015@1|root,COG0015@2|Bacteria,3Y2QW@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS2_k127_2709867_20	1267535.KB906767_gene5066	1.95e-42	162.0	COG0784@1|root,COG0784@2|Bacteria,3Y8JB@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2709867_4	234267.Acid_4577	2.961e-178	573.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_2709867_24	1340493.JNIF01000003_gene4160	5.172e-32	135.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_2709867_13	33876.JNXY01000011_gene9379	2.062e-86	302.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GDHHQS2_k127_2709867_2	278963.ATWD01000001_gene4176	7.105e-200	651.0	COG1629@1|root,COG4771@2|Bacteria,3Y3NM@57723|Acidobacteria,2JI5I@204432|Acidobacteriia	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2717432_3	1267535.KB906767_gene4915	7.338e-23	113.0	COG3307@1|root,COG3307@2|Bacteria,3Y88V@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_2717432_1	234267.Acid_7810	2.809e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,3Y70Y@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
GDHHQS2_k127_2717432_0	234267.Acid_4624	9.629e-213	683.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_2717432_2	234267.Acid_7476	7.842e-50	180.0	COG0381@1|root,COG0381@2|Bacteria,3Y50B@57723|Acidobacteria	57723|Acidobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS2_k127_2722261_2	1340493.JNIF01000004_gene969	2.299e-27	118.0	COG4206@1|root,COG4206@2|Bacteria,3Y30M@57723|Acidobacteria	57723|Acidobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_2722261_0	234267.Acid_7716	1.923e-99	332.0	COG3386@1|root,COG3386@2|Bacteria,3Y5XH@57723|Acidobacteria	57723|Acidobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_2722261_1	234267.Acid_1132	2.882e-59	220.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
GDHHQS2_k127_2724392_0	234267.Acid_4186	2.643e-117	401.0	COG3485@1|root,COG3485@2|Bacteria,3Y3AH@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2725127_2	234267.Acid_7492	2.598e-70	255.0	28P7U@1|root,2ZC21@2|Bacteria,3Y7PG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2725127_0	234267.Acid_7028	8.735e-168	539.0	COG0154@1|root,COG0154@2|Bacteria	2|Bacteria	J	amidase activity	gatA3	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_2725127_1	1340493.JNIF01000004_gene614	9.881e-89	308.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2725127_5	1125863.JAFN01000001_gene1992	3.413e-09	61.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_2725127_3	682795.AciX8_0264	1.347e-62	233.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2732646_5	234267.Acid_4728	3.259e-96	319.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_2732646_8	575590.HMPREF0156_01395	6.059e-39	155.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes	976|Bacteroidetes	F	DNA RNA non-specific endonuclease	nucA_1	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_2732646_9	926549.KI421517_gene126	1.059e-12	76.0	COG1312@1|root,COG1312@2|Bacteria,4NIMS@976|Bacteroidetes,47JVK@768503|Cytophagia	976|Bacteroidetes	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_2732646_7	234267.Acid_1290	1.048e-41	173.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,cNMP_binding
GDHHQS2_k127_2732646_0	234267.Acid_4968	1.34e-222	715.0	COG0308@1|root,COG0308@2|Bacteria,3Y31F@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS2_k127_2732646_2	234267.Acid_0579	1.476e-103	344.0	COG3394@1|root,COG3394@2|Bacteria,3Y441@57723|Acidobacteria	57723|Acidobacteria	G	PFAM YdjC family protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
GDHHQS2_k127_2732646_1	1267535.KB906767_gene3564	1.585e-105	353.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS2_k127_2732646_4	234267.Acid_0581	1.12e-97	326.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS2_k127_2732646_3	234267.Acid_0582	3.39e-102	346.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria	57723|Acidobacteria	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS2_k127_2732646_6	234267.Acid_0583	3.619e-46	185.0	COG3191@1|root,COG3191@2|Bacteria,3Y6EN@57723|Acidobacteria	57723|Acidobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GDHHQS2_k127_2733057_3	595460.RRSWK_04106	9.923e-145	469.0	COG1506@1|root,COG1506@2|Bacteria,2IWTJ@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS2_k127_2733057_8	1267535.KB906767_gene1540	1.336e-15	81.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2733057_9	639030.JHVA01000001_gene620	1.676e-06	59.0	COG1629@1|root,COG4771@2|Bacteria,3Y6I7@57723|Acidobacteria,2JK86@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2733057_6	521674.Plim_2940	9.854e-64	232.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_2733057_7	266117.Rxyl_2737	1.078e-60	216.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CQDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GDHHQS2_k127_2733057_4	80884.CCF33970	2.553e-125	413.0	COG1804@1|root,KOG3957@2759|Eukaryota,39UR2@33154|Opisthokonta,3NZAI@4751|Fungi,3QQM3@4890|Ascomycota,217F8@147550|Sordariomycetes,1EYTV@1028384|Glomerellales	4751|Fungi	I	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS2_k127_2733057_0	1121378.KB899729_gene4108	2.97e-197	623.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	acd	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_2733057_2	1121378.KB899729_gene4104	6.125e-155	500.0	COG2079@1|root,COG2079@2|Bacteria,1WMR6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GDHHQS2_k127_2733057_5	1185876.BN8_03987	5.29e-93	316.0	COG2021@1|root,COG2021@2|Bacteria,4NHJ4@976|Bacteroidetes,47NTI@768503|Cytophagia	976|Bacteroidetes	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GDHHQS2_k127_2733057_1	344747.PM8797T_17407	8.922e-190	602.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2736525_3	1569209.BBPH01000207_gene690	3.989e-19	94.0	2BWZZ@1|root,2Z86E@2|Bacteria,1MW89@1224|Proteobacteria,2U08W@28211|Alphaproteobacteria,2PUFW@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
GDHHQS2_k127_2736525_0	1207063.P24_08114	5.719e-100	339.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,2JQ96@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
GDHHQS2_k127_2736525_2	1313172.YM304_17160	4.647e-32	142.0	COG1024@1|root,COG1024@2|Bacteria,2HG19@201174|Actinobacteria,4CNYE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS2_k127_2736525_1	1120983.KB894573_gene126	1.31e-69	243.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,1JNSZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04116	ko00362,ko01120,map00362,map01120	M00540	R05620	RC00004,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2745761_0	1122138.AQUZ01000015_gene6875	7.731e-69	245.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4DQMZ@85009|Propionibacteriales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_2745761_1	1449065.JMLL01000010_gene1189	9.453e-27	113.0	COG1309@1|root,COG1309@2|Bacteria,1RGCX@1224|Proteobacteria,2UEW7@28211|Alphaproteobacteria,43PHZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
GDHHQS2_k127_2748594_1	1499967.BAYZ01000062_gene6031	1.452e-33	145.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS2_k127_2748594_0	1121904.ARBP01000011_gene1522	1.884e-34	138.0	2DBP2@1|root,2ZA71@2|Bacteria,4NFFI@976|Bacteroidetes,47NDZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2752823_1	234267.Acid_6539	2.588e-40	152.0	COG2930@1|root,COG2930@2|Bacteria,3Y2F0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
GDHHQS2_k127_2752823_0	1121930.AQXG01000003_gene2657	5.083e-160	516.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GDHHQS2_k127_2758248_0	234267.Acid_6872	4.214e-289	902.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS2_k127_2760350_6	1267535.KB906767_gene4310	6.23e-104	348.0	COG2377@1|root,COG2377@2|Bacteria,3Y3CU@57723|Acidobacteria,2JI1E@204432|Acidobacteriia	204432|Acidobacteriia	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
GDHHQS2_k127_2760350_0	234267.Acid_4760	0.0	1172.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS2_k127_2760350_1	1267535.KB906767_gene4308	2.508e-211	662.0	COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS2_k127_2760350_4	1340493.JNIF01000004_gene759	5.167e-128	419.0	COG0667@1|root,COG0667@2|Bacteria,3Y6M9@57723|Acidobacteria	57723|Acidobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_2760350_2	1340493.JNIF01000004_gene761	4.83e-149	478.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_2760350_3	1340493.JNIF01000004_gene762	1.592e-132	432.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_2760350_14	713587.THITH_00215	6.53e-08	63.0	COG5464@1|root,COG5464@2|Bacteria,1R5BN@1224|Proteobacteria,1RYWQ@1236|Gammaproteobacteria,1WXGK@135613|Chromatiales	135613|Chromatiales	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GDHHQS2_k127_2760350_8	234267.Acid_7237	2.403e-76	273.0	COG5551@1|root,COG5551@2|Bacteria,3Y7HB@57723|Acidobacteria	57723|Acidobacteria	S	Pfam:DUF2276	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
GDHHQS2_k127_2760350_7	452637.Oter_1681	1.318e-100	356.0	COG0577@1|root,COG0577@2|Bacteria,46UHH@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2760350_11	234267.Acid_4793	1.064e-29	119.0	2BYAI@1|root,315Y9@2|Bacteria,3Y52S@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2760350_12	234267.Acid_1028	2.266e-23	101.0	COG2331@1|root,COG2331@2|Bacteria,3Y92S@57723|Acidobacteria	57723|Acidobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS2_k127_2760350_5	234267.Acid_1026	5.917e-114	386.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS2_k127_2760350_13	1499967.BAYZ01000014_gene6399	5.043e-13	81.0	COG0535@1|root,COG0535@2|Bacteria,2NR6I@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS2_k127_2760350_10	452637.Oter_2644	2.668e-49	189.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,3K828@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS2_k127_2760919_2	698761.RTCIAT899_CH18065	3.408e-19	91.0	COG1680@1|root,COG1680@2|Bacteria,1PDR2@1224|Proteobacteria,2U487@28211|Alphaproteobacteria,4BC3V@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2760919_3	1504672.669787570	1.106e-11	66.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2VN0J@28216|Betaproteobacteria,4AE2W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
GDHHQS2_k127_2760919_0	1210884.HG799465_gene11875	1.098e-89	310.0	COG1680@1|root,COG1680@2|Bacteria,2IX14@203682|Planctomycetes	203682|Planctomycetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2760919_1	1340493.JNIF01000003_gene3450	7.752e-26	117.0	COG1802@1|root,COG1802@2|Bacteria,3Y849@57723|Acidobacteria	57723|Acidobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_2768493_1	1485545.JQLW01000009_gene44	3.025e-31	129.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria	1224|Proteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
GDHHQS2_k127_2768493_0	1230476.C207_02131	3.366e-43	173.0	COG0438@1|root,COG0438@2|Bacteria,1N2J8@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2768493_2	465541.ATCJ01000005_gene1543	0.0002922	49.0	COG1020@1|root,COG1028@1|root,COG3321@1|root,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K15395	-	-	-	-	ko00000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
GDHHQS2_k127_2769362_1	69395.JQLZ01000005_gene3819	8.927e-53	191.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_2769362_0	234267.Acid_1175	5.648e-232	726.0	COG0531@1|root,COG0531@2|Bacteria,3Y2R3@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_277463_0	204669.Acid345_4190	7.883e-39	160.0	COG1629@1|root,COG4771@2|Bacteria,3Y3P9@57723|Acidobacteria,2JHUB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_277463_1	401053.AciPR4_2763	1.358e-12	70.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria,2JKDK@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2780418_1	177437.HRM2_38320	1.848e-169	547.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42P8V@68525|delta/epsilon subdivisions,2WKIF@28221|Deltaproteobacteria,2MJ7Z@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2780418_3	234267.Acid_7250	5.329e-65	226.0	COG0386@1|root,COG0386@2|Bacteria,3Y4B8@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
GDHHQS2_k127_2780418_0	1340493.JNIF01000003_gene4275	2.567e-249	809.0	COG1629@1|root,COG4771@2|Bacteria,3Y6PD@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2780418_4	1340493.JNIF01000003_gene1837	6.912e-44	164.0	COG0735@1|root,COG0735@2|Bacteria,3Y4W2@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS2_k127_2780418_2	391625.PPSIR1_36702	1.328e-75	257.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS2_k127_2780969_1	247633.GP2143_17796	1.177e-93	315.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2780969_0	247633.GP2143_17791	1.898e-111	366.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2780969_6	1340493.JNIF01000003_gene2121	1.245e-20	97.0	2CBAE@1|root,32S20@2|Bacteria,3Y93Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2780969_2	247633.GP2143_13071	1.512e-37	147.0	2CBAE@1|root,32T11@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2780969_5	247633.GP2143_13086	9.599e-22	100.0	2FIXR@1|root,312JV@2|Bacteria,1NBAI@1224|Proteobacteria	1224|Proteobacteria	S	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
GDHHQS2_k127_2780969_7	103733.JNYO01000039_gene4496	9.782e-05	53.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4E4MP@85010|Pseudonocardiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS2_k127_2780969_4	525904.Tter_2752	2.274e-24	107.0	COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria	2|Bacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
GDHHQS2_k127_2780969_3	1242864.D187_007315	3.743e-34	136.0	COG1502@1|root,COG1502@2|Bacteria,1R4EZ@1224|Proteobacteria	1224|Proteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS2_k127_2789244_7	1340493.JNIF01000003_gene3620	1.524e-88	301.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA_2,DUF748,TamB
GDHHQS2_k127_2789244_9	234267.Acid_7348	7.673e-33	137.0	COG4031@1|root,COG4031@2|Bacteria,3Y8JK@57723|Acidobacteria	57723|Acidobacteria	S	Predicted metal-binding protein (DUF2103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2103
GDHHQS2_k127_2789244_11	1122614.JHZF01000013_gene2930	8.171e-10	62.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Hydrolase CocE NonD family	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_2789244_6	234267.Acid_3421	3.295e-105	349.0	COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria	57723|Acidobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
GDHHQS2_k127_2789244_3	204669.Acid345_4056	1.756e-149	487.0	COG4948@1|root,COG4948@2|Bacteria,3Y76H@57723|Acidobacteria,2JNKW@204432|Acidobacteriia	204432|Acidobacteriia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_2789244_2	234267.Acid_5500	1.184e-153	494.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	HemolysinCabind,Pro_isomerase
GDHHQS2_k127_2789244_1	1340493.JNIF01000003_gene3478	5.383e-165	564.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2789244_5	234267.Acid_4782	2.096e-126	415.0	COG0265@1|root,COG0265@2|Bacteria,3Y3HE@57723|Acidobacteria	57723|Acidobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_2789244_0	234267.Acid_0024	4.426e-194	634.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_2789244_10	357808.RoseRS_0844	3.788e-10	63.0	COG1669@1|root,COG1669@2|Bacteria,2G76P@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS2_k127_2789244_8	234267.Acid_4781	1.647e-61	217.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GDHHQS2_k127_2789244_4	392500.Swoo_3655	2.14e-127	425.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1T9ZD@1236|Gammaproteobacteria,2QE12@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2794395_0	1155718.KB891899_gene1824	1.125e-110	375.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K16033	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09851	RC01363	ko00000,ko00001	-	-	-	Trp_halogenase
GDHHQS2_k127_2795700_2	329726.AM1_5387	5.37e-20	93.0	COG4976@1|root,COG4976@2|Bacteria,1G290@1117|Cyanobacteria	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_2795700_0	234267.Acid_5438	2.856e-100	336.0	COG1462@1|root,COG1462@2|Bacteria,3Y3KF@57723|Acidobacteria	57723|Acidobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS2_k127_2795700_1	234267.Acid_0222	1.156e-98	328.0	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2803456_4	502025.Hoch_1675	1.073e-75	265.0	COG0500@1|root,COG2226@2|Bacteria,1N8UJ@1224|Proteobacteria	1224|Proteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_2803456_6	357276.EL88_11585	7.155e-27	119.0	2E980@1|root,333GF@2|Bacteria,4PJ5K@976|Bacteroidetes,2G255@200643|Bacteroidia,4AU3C@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2803456_2	357276.EL88_11580	1.87e-111	372.0	COG1479@1|root,COG1479@2|Bacteria,4NRVQ@976|Bacteroidetes,2FTAB@200643|Bacteroidia,4ASHM@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262,HNH
GDHHQS2_k127_2803456_0	234267.Acid_5357	6.632e-313	983.0	COG0129@1|root,COG0129@2|Bacteria,3Y3B1@57723|Acidobacteria	57723|Acidobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_2803456_1	234267.Acid_7008	1.933e-201	636.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2803456_7	1033806.HTIA_1612	8.325e-11	73.0	COG0500@1|root,arCOG04347@2157|Archaea,2XUBX@28890|Euryarchaeota,23SUV@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
GDHHQS2_k127_2803456_3	234267.Acid_1849	3.231e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,3Y6JP@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2803456_5	234267.Acid_4615	1.089e-40	154.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2804670_0	234267.Acid_1603	3.698e-77	267.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2804670_1	1267535.KB906767_gene781	1.636e-51	200.0	COG0457@1|root,COG0457@2|Bacteria,3Y7TN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2811700_1	234267.Acid_0384	9.917e-96	321.0	COG0608@1|root,COG0608@2|Bacteria,3Y3HI@57723|Acidobacteria	57723|Acidobacteria	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS2_k127_2811700_2	1267535.KB906767_gene4032	1.029e-66	235.0	COG1434@1|root,COG1434@2|Bacteria,3Y4FT@57723|Acidobacteria,2JJ4K@204432|Acidobacteriia	204432|Acidobacteriia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_2811700_3	234267.Acid_7320	6.797e-27	115.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS2_k127_2811700_0	1267535.KB906767_gene2569	3.903e-107	354.0	COG0275@1|root,COG0275@2|Bacteria,3Y31S@57723|Acidobacteria,2JHM1@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS2_k127_2811700_4	1267535.KB906767_gene2568	1.97e-16	87.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria	57723|Acidobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
GDHHQS2_k127_2812770_2	497964.CfE428DRAFT_5779	3.601e-49	180.0	COG2382@1|root,COG2382@2|Bacteria,46TS7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_2812770_0	234267.Acid_1400	6.18e-264	818.0	COG0422@1|root,COG0422@2|Bacteria,3Y2TX@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
GDHHQS2_k127_2812770_3	234267.Acid_1158	6.209e-49	181.0	2E71G@1|root,331K5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2812770_1	1340493.JNIF01000003_gene2611	3.332e-93	309.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2813225_1	1267535.KB906767_gene3553	4.729e-161	512.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS2_k127_2813225_2	234267.Acid_3377	8.229e-145	479.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria	57723|Acidobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS2_k127_2813225_6	234267.Acid_3376	4.229e-51	189.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria	57723|Acidobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS2_k127_2813225_3	234267.Acid_0467	3.395e-119	412.0	COG0463@1|root,COG1807@1|root,COG2246@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,COG2246@2|Bacteria,3Y4P3@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
GDHHQS2_k127_2813225_0	1340493.JNIF01000003_gene4764	1.733e-286	893.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2813225_8	1266925.JHVX01000014_gene1583	1.733e-09	69.0	COG5563@1|root,COG5563@2|Bacteria,1N5JV@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2813225_4	234267.Acid_1438	3.146e-115	387.0	COG1807@1|root,COG1807@2|Bacteria,3Y2K3@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2813225_7	234267.Acid_2380	1.057e-32	134.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
GDHHQS2_k127_2814425_1	234267.Acid_7665	1.837e-27	119.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_2814425_0	1396418.BATQ01000007_gene1418	2.151e-28	128.0	COG4102@1|root,COG4102@2|Bacteria,46U0B@74201|Verrucomicrobia,2IU14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2820794_3	281687.CJA02278c	5.026e-14	84.0	2C6QK@1|root,2S4BP@2759|Eukaryota,3A6WA@33154|Opisthokonta,3BTI5@33208|Metazoa,3DAHF@33213|Bilateria,40DZX@6231|Nematoda,1KWND@119089|Chromadorea,40Z59@6236|Rhabditida	33208|Metazoa	S	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_2820794_0	234267.Acid_2615	1.216e-43	175.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
GDHHQS2_k127_2820794_1	1340493.JNIF01000003_gene2666	6.344e-40	155.0	COG3222@1|root,COG3222@2|Bacteria,3Y5T4@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
GDHHQS2_k127_2820794_2	1340493.JNIF01000003_gene2667	2.591e-39	149.0	COG2010@1|root,COG2010@2|Bacteria,3Y5PY@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS2_k127_2831776_11	926566.Terro_3796	0.0007619	44.0	COG1629@1|root,COG4771@2|Bacteria,3Y9DR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2831776_8	1340493.JNIF01000003_gene3584	2.081e-80	278.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS2_k127_2831776_0	1267535.KB906767_gene3394	1.17e-272	849.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
GDHHQS2_k127_2831776_9	240015.ACP_1340	3.54e-21	97.0	2EK70@1|root,33DXD@2|Bacteria,3Y5QD@57723|Acidobacteria,2JK4E@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2831776_2	1396418.BATQ01000020_gene5035	3.536e-154	501.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_2831776_4	1267535.KB906767_gene4175	1.152e-122	405.0	COG0787@1|root,COG0787@2|Bacteria,3Y2U3@57723|Acidobacteria,2JI6I@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS2_k127_2831776_3	1267535.KB906767_gene4670	8.189e-149	478.0	COG0438@1|root,COG0438@2|Bacteria,3Y6A8@57723|Acidobacteria	57723|Acidobacteria	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_4
GDHHQS2_k127_2831776_1	234267.Acid_7442	2.553e-173	548.0	COG1216@1|root,COG1216@2|Bacteria,3Y7CJ@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2831776_7	234267.Acid_7441	7.853e-83	287.0	COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GDHHQS2_k127_2831776_6	234267.Acid_7440	1.805e-83	288.0	COG1216@1|root,COG1216@2|Bacteria,3Y80R@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2831776_5	1340493.JNIF01000003_gene2680	1.451e-110	363.0	COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2831776_10	945713.IALB_2157	6.086e-06	52.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS2_k127_2834510_0	1340493.JNIF01000003_gene4293	5.293e-186	594.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2834818_9	234267.Acid_5762	1.557e-22	104.0	COG1139@1|root,COG1139@2|Bacteria,3Y3R8@57723|Acidobacteria	57723|Acidobacteria	C	cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
GDHHQS2_k127_2834818_4	234267.Acid_5763	2.249e-101	334.0	COG0247@1|root,COG0247@2|Bacteria,3Y4IR@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
GDHHQS2_k127_2834818_8	234267.Acid_1277	2.253e-25	109.0	COG1862@1|root,COG1862@2|Bacteria,3Y5GK@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase, YajC	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS2_k127_2834818_0	1340493.JNIF01000003_gene1851	1.444e-216	684.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_2834818_1	1267535.KB906767_gene4739	4.137e-148	480.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_2834818_3	234267.Acid_1280	8.069e-102	338.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_2834818_2	1267535.KB906767_gene4741	2.489e-121	393.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
GDHHQS2_k127_2834818_6	234267.Acid_1282	1.267e-50	184.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_2834818_5	1340493.JNIF01000003_gene1846	6.84e-63	218.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_2834818_7	1340493.JNIF01000003_gene1845	3.297e-50	183.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
GDHHQS2_k127_2837136_3	1111479.AXAR01000004_gene2191	9.717e-206	653.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,278ZE@186823|Alicyclobacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2837136_4	1267535.KB906767_gene3892	3.472e-51	186.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS2_k127_2837136_2	1267535.KB906767_gene480	1.85e-211	666.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2837136_0	234267.Acid_1646	0.0	1081.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
GDHHQS2_k127_2837136_1	1340493.JNIF01000003_gene1507	3.458e-219	691.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS2_k127_2837429_1	1267534.KB906756_gene712	4.833e-39	154.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2837429_2	234267.Acid_7589	7.615e-34	143.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_7589|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2837429_0	234267.Acid_2370	2.485e-94	316.0	COG0687@1|root,COG0687@2|Bacteria,3Y5JD@57723|Acidobacteria	57723|Acidobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS2_k127_2837751_0	234267.Acid_2269	2.252e-165	546.0	COG3391@1|root,COG5555@1|root,COG3391@2|Bacteria,COG5555@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Metallophos
GDHHQS2_k127_2837751_1	234267.Acid_6845	9.185e-130	426.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	57723|Acidobacteria	I	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
GDHHQS2_k127_2843594_5	234267.Acid_7025	1.301e-44	169.0	2F5GG@1|root,33Y23@2|Bacteria,3Y7UU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2843594_0	234267.Acid_6404	1.139e-134	439.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_2843594_4	1340493.JNIF01000004_gene743	9.227e-52	188.0	2F82T@1|root,340G8@2|Bacteria,3Y8B9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2843594_2	234267.Acid_7430	2.957e-123	412.0	COG0604@1|root,COG0604@2|Bacteria,3Y35U@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_2843594_6	224911.27351870	2.257e-07	61.0	2BZNS@1|root,34AU2@2|Bacteria,1P67Z@1224|Proteobacteria,2U2V2@28211|Alphaproteobacteria,3JWXI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2843594_1	234267.Acid_5324	1.453e-124	417.0	COG2271@1|root,COG2271@2|Bacteria,3Y47N@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_2843594_3	1267535.KB906767_gene4145	7.382e-87	297.0	COG1629@1|root,COG1629@2|Bacteria,3Y2JN@57723|Acidobacteria,2JI08@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2850147_6	234267.Acid_7512	4.011e-42	160.0	COG1538@1|root,COG1538@2|Bacteria,3Y54R@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_2850147_4	234267.Acid_7513	4.941e-121	403.0	COG0845@1|root,COG0845@2|Bacteria,3Y49U@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,YtkA
GDHHQS2_k127_2850147_0	335543.Sfum_2246	0.0	1538.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MRHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
GDHHQS2_k127_2850147_3	1267535.KB906767_gene1544	8.506e-185	586.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS2_k127_2850147_5	234267.Acid_0191	5.067e-56	217.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	phlE	-	-	ko:K02511,ko:K02575,ko:K13021	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.14.3,2.A.1.14.9,2.A.1.8	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_2850147_2	278957.ABEA03000133_gene1572	1.245e-185	602.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,3K757@414999|Opitutae	414999|Opitutae	C	PFAM coagulation factor 5 8 type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,FAD_oxidored,Laminin_G_3
GDHHQS2_k127_2850147_1	1340493.JNIF01000003_gene4022	2.925e-247	774.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_2852434_1	234267.Acid_5827	3.974e-182	593.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
GDHHQS2_k127_2852434_2	234267.Acid_2032	9.543e-120	400.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_2852434_3	886293.Sinac_1155	6.073e-58	218.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
GDHHQS2_k127_2852434_0	234267.Acid_7369	8.944e-220	695.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_2852434_4	639030.JHVA01000001_gene1568	2.65e-56	203.0	COG5042@1|root,COG5042@2|Bacteria,3Y2QK@57723|Acidobacteria,2JIUB@204432|Acidobacteriia	204432|Acidobacteriia	F	PFAM purine nucleoside permease	-	-	-	-	-	-	-	-	-	-	-	-	NUP
GDHHQS2_k127_2852836_2	103733.JNYO01000001_gene38	4.425e-34	148.0	28M6Z@1|root,2ZAKH@2|Bacteria,2IA92@201174|Actinobacteria,4E1TU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2852836_0	1123242.JH636434_gene3333	2.064e-123	407.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_2852836_1	234267.Acid_1746	5.093e-100	339.0	COG1723@1|root,COG1723@2|Bacteria,3Y43W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2855502_0	1340493.JNIF01000003_gene3565	6.954e-232	739.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2855502_1	234267.Acid_2699	1.135e-54	210.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AhpC-TSA,CarboxypepD_reg,PDZ_2,Plug,TonB_dep_Rec
GDHHQS2_k127_2855502_2	485913.Krac_5296	8.206e-13	70.0	COG1680@1|root,COG1680@2|Bacteria,2G7A9@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2861972_1	344747.PM8797T_29708	5.777e-112	368.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
GDHHQS2_k127_2861972_0	1340493.JNIF01000003_gene3464	1.828e-144	466.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2866203_1	344747.PM8797T_09494	2.635e-22	102.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_09690	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_2866203_0	1340493.JNIF01000003_gene1379	3.11e-153	511.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,DUF5122,He_PIG,NHL
GDHHQS2_k127_2866203_2	234267.Acid_4921	3.193e-10	74.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Collagen
GDHHQS2_k127_2869392_1	371731.Rsw2DRAFT_2303	2.294e-98	326.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,1FCWS@1060|Rhodobacter	28211|Alphaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_2869392_0	1342301.JASD01000008_gene3368	3.517e-137	442.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,3ZXBK@60136|Sulfitobacter	28211|Alphaproteobacteria	BQ	Histone deacetylase domain	aphA	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_2880305_1	497964.CfE428DRAFT_0772	2.277e-82	299.0	COG0457@1|root,COG0457@2|Bacteria,46U9B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
GDHHQS2_k127_2880305_0	761193.Runsl_0171	2.921e-150	499.0	COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,47MIF@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA dehydrogenase C-terminal like	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
GDHHQS2_k127_2888450_1	1340493.JNIF01000003_gene3461	1.031e-169	544.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2888450_2	1123508.JH636439_gene875	5.365e-161	539.0	COG2010@1|root,COG2010@2|Bacteria,2IXDW@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2888450_0	234267.Acid_3687	4.912e-308	957.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_2888450_3	401053.AciPR4_2818	8.041e-114	374.0	COG0591@1|root,COG0591@2|Bacteria,3Y6NZ@57723|Acidobacteria,2JMN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_2891224_0	1267535.KB906767_gene1639	2.011e-153	520.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2895251_8	1340493.JNIF01000004_gene437	9.329e-54	198.0	COG0101@1|root,COG0101@2|Bacteria,3Y833@57723|Acidobacteria	57723|Acidobacteria	J	tRNA pseudouridine synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
GDHHQS2_k127_2895251_10	1304874.JAFY01000002_gene91	2.006e-44	173.0	COG0631@1|root,COG0631@2|Bacteria,3TBMH@508458|Synergistetes	508458|Synergistetes	T	PFAM Stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
GDHHQS2_k127_2895251_7	1267535.KB906767_gene5280	1.465e-59	210.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
GDHHQS2_k127_2895251_12	485913.Krac_12202	1.368e-10	73.0	COG1082@1|root,COG1082@2|Bacteria,2G8PD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2895251_0	234267.Acid_5921	6.781e-271	869.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2895251_4	234267.Acid_3241	2.447e-119	389.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS2_k127_2895251_5	1340493.JNIF01000003_gene4512	6.549e-68	245.0	COG4589@1|root,COG4589@2|Bacteria,3Y59Y@57723|Acidobacteria	57723|Acidobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS2_k127_2895251_6	234267.Acid_5766	8.865e-64	224.0	COG1994@1|root,COG1994@2|Bacteria,3Y58P@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_2895251_11	1096546.WYO_2663	4.711e-17	92.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_23
GDHHQS2_k127_2895251_2	234267.Acid_1146	1.726e-204	648.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2895251_1	1340493.JNIF01000004_gene819	1.866e-250	800.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_2895251_9	1340493.JNIF01000003_gene3565	1.187e-47	182.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2899081_0	278963.ATWD01000001_gene3345	7.578e-92	323.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2903507_5	526227.Mesil_0382	2.289e-54	192.0	COG1505@1|root,COG1505@2|Bacteria,1WMDW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_2903507_0	1340493.JNIF01000004_gene829	3.653e-257	804.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_2903507_3	1134912.AJTV01000021_gene3005	3.095e-115	385.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,2U2RP@28211|Alphaproteobacteria,36ZV4@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GDHHQS2_k127_2903507_2	886293.Sinac_6486	5.387e-128	434.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_2903507_1	234267.Acid_3351	2.267e-147	474.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_2903507_4	234267.Acid_7492	2.462e-80	289.0	28P7U@1|root,2ZC21@2|Bacteria,3Y7PG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2903507_6	935836.JAEL01000009_gene3837	2.981e-25	115.0	COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus	91061|Bacilli	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
GDHHQS2_k127_2909572_1	1340493.JNIF01000004_gene597	8.587e-140	468.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2909572_0	234267.Acid_4151	0.0	1327.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_2909572_3	234267.Acid_4152	9.44e-97	332.0	COG0845@1|root,COG0845@2|Bacteria,3Y4YK@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_2909572_2	234267.Acid_4153	2.628e-113	382.0	COG1538@1|root,COG1538@2|Bacteria,3Y5F3@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_2909572_5	234267.Acid_4150	3.918e-21	94.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GDHHQS2_k127_2909572_6	595460.RRSWK_05427	2.439e-09	60.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
GDHHQS2_k127_2909572_4	314230.DSM3645_18936	3.442e-87	314.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_2916553_2	240015.ACP_1261	6.677e-12	70.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_2916553_1	1356852.N008_00270	2.467e-101	339.0	COG0189@1|root,COG0189@2|Bacteria,4NJI8@976|Bacteroidetes,47JGF@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
GDHHQS2_k127_2916553_0	234267.Acid_1077	1.013e-109	359.0	COG0657@1|root,COG1520@1|root,COG0657@2|Bacteria,COG1520@2|Bacteria,3Y44Z@57723|Acidobacteria	57723|Acidobacteria	I	Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,PQQ_2
GDHHQS2_k127_2932269_0	234267.Acid_0069	4.602e-304	960.0	COG1391@1|root,COG1391@2|Bacteria,3Y72J@57723|Acidobacteria	57723|Acidobacteria	H	Glutamate-ammonia ligase adenylyltransferase	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
GDHHQS2_k127_2932269_1	1210884.HG799462_gene8193	4.331e-59	214.0	COG3781@1|root,COG3781@2|Bacteria,2IZZ2@203682|Planctomycetes	203682|Planctomycetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
GDHHQS2_k127_2932269_2	1122222.AXWR01000052_gene66	5.17e-17	92.0	2ENQZ@1|root,33GC6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2938767_2	234267.Acid_3379	5.976e-57	205.0	COG0547@1|root,COG0547@2|Bacteria,3Y3YF@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS2_k127_2938767_1	314230.DSM3645_18556	1.084e-64	237.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	BNR,BNR_2
GDHHQS2_k127_2938767_3	1267535.KB906767_gene4177	9.24e-08	61.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_2938767_0	234267.Acid_5870	2.997e-69	244.0	COG1082@1|root,COG1082@2|Bacteria,3Y7AM@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_2943205_2	1207055.C100_12065	2.013e-37	147.0	COG0657@1|root,COG0657@2|Bacteria,1R79Q@1224|Proteobacteria,2U6W0@28211|Alphaproteobacteria,2K0EW@204457|Sphingomonadales	204457|Sphingomonadales	I	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS2_k127_2943205_1	1449347.JQLN01000005_gene3950	3.883e-41	175.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,CarboxypepD_reg,DUF4347,RCC1_2
GDHHQS2_k127_2943205_5	234267.Acid_4124	8.99e-06	59.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
GDHHQS2_k127_2943205_4	1267535.KB906767_gene804	4.765e-08	67.0	COG4409@1|root,COG5563@1|root,COG4409@2|Bacteria,COG5563@2|Bacteria,3Y9G0@57723|Acidobacteria,2JNS2@204432|Acidobacteriia	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	CP_1076	-	3.2.1.52	ko:K12373,ko:K21449	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko02000,ko03110	1.B.40.2	GH20	-	BNR_2,DUF1929
GDHHQS2_k127_2943205_3	1267535.KB906767_gene5521	3.687e-36	144.0	COG1678@1|root,COG1678@2|Bacteria,3Y8TX@57723|Acidobacteria	57723|Acidobacteria	K	Uncharacterized ACR, COG1678	-	-	-	-	-	-	-	-	-	-	-	-	DUF179
GDHHQS2_k127_2943205_0	1396418.BATQ01000049_gene423	8.031e-186	595.0	COG3356@1|root,COG3356@2|Bacteria,46UGT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2946748_0	927677.ALVU02000001_gene2487	5.115e-12	78.0	2CC1C@1|root,2ZVZA@2|Bacteria,1G6DH@1117|Cyanobacteria,1H5Z5@1142|Synechocystis	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2947169_2	234267.Acid_7573	6.878e-141	479.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_2947169_1	1340493.JNIF01000004_gene118	2.987e-146	476.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria	57723|Acidobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_2947169_3	1340493.JNIF01000003_gene4648	4.392e-82	295.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS2_k127_2947169_0	1267535.KB906767_gene1458	1.327e-242	759.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS2_k127_2947295_0	179408.Osc7112_3588	7.917e-144	473.0	COG0001@1|root,COG0236@1|root,COG3321@1|root,COG0001@2|Bacteria,COG0236@2|Bacteria,COG3321@2|Bacteria,1G25N@1117|Cyanobacteria,1HA4D@1150|Oscillatoriales	1117|Cyanobacteria	HQ	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
GDHHQS2_k127_2949731_0	1340493.JNIF01000003_gene2517	2.034e-314	996.0	COG1629@1|root,COG4771@2|Bacteria,3Y3NM@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2949837_1	1267535.KB906767_gene965	5.841e-60	222.0	COG4975@1|root,COG4975@2|Bacteria,3Y6YG@57723|Acidobacteria	57723|Acidobacteria	G	Ureide permease	-	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
GDHHQS2_k127_2949837_0	234267.Acid_2822	1.749e-69	243.0	28J3W@1|root,2Z900@2|Bacteria,3Y47Q@57723|Acidobacteria	57723|Acidobacteria	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
GDHHQS2_k127_2949837_2	278963.ATWD01000001_gene1607	2.58e-59	213.0	COG2353@1|root,COG2353@2|Bacteria,3Y4PV@57723|Acidobacteria,2JMPN@204432|Acidobacteriia	204432|Acidobacteriia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_2949837_3	234267.Acid_2715	2.318e-42	163.0	COG1988@1|root,COG1988@2|Bacteria,3Y305@57723|Acidobacteria	57723|Acidobacteria	S	membrane-bound metal-dependent hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS2_k127_2951736_1	234267.Acid_6721	2.781e-145	475.0	COG1228@1|root,COG1228@2|Bacteria,3Y6JN@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_2951736_0	234267.Acid_6720	1.069e-186	594.0	COG1228@1|root,COG1228@2|Bacteria,3Y6Y2@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_2951736_2	1340493.JNIF01000003_gene3002	3.341e-21	97.0	COG1228@1|root,COG1228@2|Bacteria,3Y6WV@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_2955477_1	234267.Acid_5620	2.42e-72	252.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
GDHHQS2_k127_2955477_3	234267.Acid_5619	2.693e-53	198.0	COG0780@1|root,COG0780@2|Bacteria,3Y4ND@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GDHHQS2_k127_2955477_0	1267535.KB906767_gene917	5.323e-196	618.0	COG1915@1|root,COG1915@2|Bacteria,3Y6MM@57723|Acidobacteria	57723|Acidobacteria	S	LOR/SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
GDHHQS2_k127_2955477_4	1415780.JPOG01000001_gene723	0.0004055	49.0	COG4113@1|root,COG4113@2|Bacteria,1NB4U@1224|Proteobacteria,1SPFK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_2955477_2	1340493.JNIF01000004_gene597	2.086e-70	252.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2956269_4	234267.Acid_6143	6.73e-65	233.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS2_k127_2956269_0	234267.Acid_5393	3.268e-191	606.0	COG2256@1|root,COG2256@2|Bacteria,3Y3F7@57723|Acidobacteria	57723|Acidobacteria	L	AAA ATPase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GDHHQS2_k127_2956269_3	234267.Acid_5394	6.735e-83	292.0	COG0566@1|root,COG0566@2|Bacteria,3Y4GM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS2_k127_2956269_2	661478.OP10G_0409	2.008e-84	291.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
GDHHQS2_k127_2956269_1	234267.Acid_7240	6.866e-135	441.0	COG0542@1|root,COG2204@1|root,COG0542@2|Bacteria,COG2204@2|Bacteria,3Y6T8@57723|Acidobacteria	57723|Acidobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small,Response_reg
GDHHQS2_k127_2956269_5	1267535.KB906767_gene689	2.303e-38	143.0	COG0361@1|root,COG0361@2|Bacteria,3Y8IP@57723|Acidobacteria	57723|Acidobacteria	J	Translation initiation factor 1A / IF-1	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS2_k127_2956382_0	1340493.JNIF01000003_gene3118	2.142e-253	822.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
GDHHQS2_k127_2956382_2	1123508.JH636442_gene3935	2.458e-220	691.0	COG1228@1|root,COG1228@2|Bacteria,2IYHF@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_2956382_3	234267.Acid_6066	4.617e-16	83.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_6066|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2956382_1	1340493.JNIF01000003_gene3903	1.487e-237	741.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_2956469_2	1288826.MSNKSG1_16636	1.034e-33	144.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,465CJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GDHHQS2_k127_2956469_3	1184267.A11Q_2165	1.083e-08	67.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2MSND@213481|Bdellovibrionales,2WIT0@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2956469_1	296591.Bpro_2458	9.327e-47	172.0	COG0835@1|root,COG0835@2|Bacteria,1N1YU@1224|Proteobacteria,2VV4H@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_2956469_0	296591.Bpro_2459	7.88e-145	473.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,2W8ZD@28216|Betaproteobacteria,4AFA1@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
GDHHQS2_k127_2958641_4	234267.Acid_7409	1.574e-89	302.0	COG0438@1|root,COG0438@2|Bacteria,3Y68S@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2958641_9	1340493.JNIF01000003_gene2469	5.235e-34	143.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_3,HATPase_c,HTH_8,HisKA,Hpt,PAS_4,Response_reg
GDHHQS2_k127_2958641_2	1340493.JNIF01000003_gene2468	7.744e-121	397.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HZ@57723|Acidobacteria	57723|Acidobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2958641_10	1429046.RR21198_3297	1.148e-24	108.0	COG0662@1|root,COG0662@2|Bacteria,2GSNK@201174|Actinobacteria,4G1K1@85025|Nocardiaceae	201174|Actinobacteria	G	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
GDHHQS2_k127_2958641_7	234267.Acid_7407	1.611e-54	198.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,3Y4FC@57723|Acidobacteria	57723|Acidobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
GDHHQS2_k127_2958641_5	234267.Acid_1861	1.458e-69	241.0	COG0245@1|root,COG0245@2|Bacteria,3Y3WG@57723|Acidobacteria	57723|Acidobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GDHHQS2_k127_2958641_3	1267535.KB906767_gene3485	3.043e-93	313.0	COG1211@1|root,COG1211@2|Bacteria,3Y3VR@57723|Acidobacteria,2JI25@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
GDHHQS2_k127_2958641_1	234267.Acid_1863	3.879e-156	500.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria	57723|Acidobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GDHHQS2_k127_2958641_8	234267.Acid_7355	2.4e-45	168.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS2_k127_2958641_6	1429916.X566_21020	5.457e-69	241.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS2_k127_2958641_0	1267535.KB906767_gene4538	7.353e-160	509.0	COG0042@1|root,COG0042@2|Bacteria,3Y3XE@57723|Acidobacteria,2JI1U@204432|Acidobacteriia	204432|Acidobacteriia	J	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Dus
GDHHQS2_k127_2961976_0	234267.Acid_7867	2.195e-63	225.0	COG0664@1|root,COG0664@2|Bacteria,3Y4WU@57723|Acidobacteria	57723|Acidobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS2_k127_2961976_2	1231391.AMZF01000067_gene3424	2.439e-13	77.0	COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,3T3VG@506|Alcaligenaceae	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS2_k127_2961976_3	292459.STH2396	9.597e-05	53.0	28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,257E3@186801|Clostridia	186801|Clostridia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
GDHHQS2_k127_2971681_2	314230.DSM3645_20627	3.791e-100	341.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_2971681_3	314230.DSM3645_14810	3.345e-53	203.0	COG1520@1|root,COG1520@2|Bacteria,2IX03@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_2971681_1	234267.Acid_0784	1.201e-191	615.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_2971681_0	1340493.JNIF01000003_gene4529	2.402e-228	746.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2971681_4	313624.NSP_20470	3.387e-23	106.0	COG3177@1|root,COG3177@2|Bacteria,1GBCB@1117|Cyanobacteria,1HK8F@1161|Nostocales	1117|Cyanobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
GDHHQS2_k127_2971681_5	1869.MB27_11960	0.0009664	49.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DUF4376,HTH_21,HTH_Tnp_1,rve_3
GDHHQS2_k127_2971945_1	234267.Acid_0024	7.736e-190	622.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_2971945_5	1313172.YM304_03740	0.0001492	49.0	COG4102@1|root,COG5164@1|root,COG4102@2|Bacteria,COG5164@2|Bacteria	2|Bacteria	K	cell wall organization	-	-	2.7.11.1	ko:K14949	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	DUF1501,Pkinase
GDHHQS2_k127_2971945_0	1267535.KB906767_gene706	1.917e-321	998.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS2_k127_2971945_2	234267.Acid_1286	4.663e-54	191.0	COG3536@1|root,COG3536@2|Bacteria,3Y4UI@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
GDHHQS2_k127_2971945_3	234267.Acid_6742	1.134e-27	122.0	2DYK5@1|root,34A5U@2|Bacteria,3Y8GF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
GDHHQS2_k127_2971945_4	446465.Bfae_29140	1.808e-14	81.0	COG2207@1|root,COG2207@2|Bacteria,2I6BP@201174|Actinobacteria	201174|Actinobacteria	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
GDHHQS2_k127_297621_0	760192.Halhy_6811	1.582e-121	402.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_2976298_1	1197130.BAFM01000011_gene2075	6.383e-27	113.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,23W1W@183963|Halobacteria	183963|Halobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
GDHHQS2_k127_2976298_0	234267.Acid_5899	4.377e-85	302.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS2_k127_2989019_2	35725.K2STE5	5.058e-39	152.0	COG3119@1|root,KOG3867@2759|Eukaryota,38I60@33154|Opisthokonta,3P0W3@4751|Fungi,3QP3Z@4890|Ascomycota,2046D@147541|Dothideomycetes	4751|Fungi	P	Sulfatase	-	-	3.10.1.1	ko:K01565	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07814	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_2989019_3	635013.TherJR_2348	2.428e-19	96.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_2989019_1	1340493.JNIF01000004_gene736	5.098e-170	562.0	COG1680@1|root,COG1680@2|Bacteria,3Y6TE@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2989019_0	639030.JHVA01000001_gene590	5.764e-200	662.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2992056_1	1340493.JNIF01000004_gene284	1.665e-155	504.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase,Hepar_II_III,Hepar_II_III_N
GDHHQS2_k127_2992056_0	234267.Acid_2009	4.917e-224	711.0	COG1629@1|root,COG4771@2|Bacteria,3Y66T@57723|Acidobacteria	57723|Acidobacteria	P	PFAM TonB-dependent Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_2996756_1	682795.AciX8_2271	1.949e-260	838.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_2996756_2	1267535.KB906767_gene310	1.159e-176	563.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_2996756_3	1382359.JIAL01000001_gene2875	1.154e-69	243.0	2CAZH@1|root,2Z7RU@2|Bacteria,3Y4WA@57723|Acidobacteria,2JKHZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
GDHHQS2_k127_2996756_0	1382359.JIAL01000001_gene2876	2.245e-289	895.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria,2JIC4@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_300355_1	1003200.AXXA_13989	5.517e-56	201.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2VI1C@28216|Betaproteobacteria,3T1KH@506|Alcaligenaceae	28216|Betaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_300355_0	1123377.AUIV01000012_gene708	4.81e-62	219.0	2E585@1|root,3300K@2|Bacteria,1N9MI@1224|Proteobacteria,1SDGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_300355_2	216142.LT40_20525	3.963e-48	181.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_300355_5	526225.Gobs_3752	4.958e-07	55.0	COG4118@1|root,COG4118@2|Bacteria,2GQNI@201174|Actinobacteria,4EW86@85013|Frankiales	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_300355_4	643648.Slip_1886	9.83e-10	62.0	COG1848@1|root,COG1848@2|Bacteria,1V5H5@1239|Firmicutes,24HS5@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_3011778_2	1123242.JH636434_gene5302	5.155e-15	78.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3011778_0	1267535.KB906767_gene4894	7.459e-241	754.0	COG2721@1|root,COG2721@2|Bacteria,3Y722@57723|Acidobacteria	57723|Acidobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.42	ko:K01708	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	GD_AH_C,SAF
GDHHQS2_k127_3011778_3	365046.Rta_32230	8.931e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,4AESS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_4,TPR_8
GDHHQS2_k127_3011778_1	401053.AciPR4_2257	3.63e-140	464.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria,2JMM3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3015692_1	234267.Acid_5922	1.595e-188	597.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_3015692_6	768671.ThimaDRAFT_1597	1.282e-34	147.0	COG3291@1|root,COG5640@1|root,COG3291@2|Bacteria,COG5640@2|Bacteria,1QXA4@1224|Proteobacteria	1224|Proteobacteria	O	endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GDHHQS2_k127_3015692_4	1267535.KB906767_gene4335	1.745e-75	266.0	2F1JK@1|root,33UK0@2|Bacteria,3Y7KY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3015692_3	234267.Acid_0771	5.83e-135	440.0	COG0763@1|root,COG0763@2|Bacteria,3Y34H@57723|Acidobacteria	57723|Acidobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS2_k127_3015692_0	234267.Acid_0772	9.1e-264	827.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
GDHHQS2_k127_3015692_5	330214.NIDE2144	2.583e-48	175.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	GO:0001666,GO:0006355,GO:0006950,GO:0008150,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010565,GO:0010605,GO:0010629,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036293,GO:0040008,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_37
GDHHQS2_k127_3015692_7	330214.NIDE2143	1.734e-29	118.0	COG4683@1|root,COG4683@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	VY92_07350	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_3015692_2	1267535.KB906767_gene3116	2.52e-174	554.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_3032447_0	234267.Acid_3798	2.488e-108	367.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3032447_1	234267.Acid_3798	4.153e-98	342.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3036572_0	234267.Acid_7524	4.869e-183	586.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria	57723|Acidobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_3036572_1	234267.Acid_7523	1.631e-88	300.0	COG0612@1|root,COG0612@2|Bacteria,3Y322@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_30393_3	880072.Desac_1814	1.522e-06	55.0	2CE1N@1|root,32RYY@2|Bacteria,1NB5H@1224|Proteobacteria,431G8@68525|delta/epsilon subdivisions,2WWTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_30393_2	251221.35211476	1.468e-22	102.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_30393_0	1340493.JNIF01000003_gene1340	3.208e-159	514.0	COG0277@1|root,COG0277@2|Bacteria,3Y766@57723|Acidobacteria	57723|Acidobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS2_k127_30393_1	926569.ANT_29930	3.511e-38	147.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
GDHHQS2_k127_3048372_1	330214.NIDE3734	1.864e-101	333.0	COG0356@1|root,COG0356@2|Bacteria,3J0RW@40117|Nitrospirae	40117|Nitrospirae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS2_k127_3048372_2	330214.NIDE3735	7.605e-28	113.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
GDHHQS2_k127_3048372_0	635013.TherJR_2970	9.801e-118	395.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26020@186807|Peptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
GDHHQS2_k127_3049409_1	566461.SSFG_06161	4.886e-31	129.0	COG1262@1|root,COG1262@2|Bacteria,2GN0F@201174|Actinobacteria	201174|Actinobacteria	G	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_3049409_0	1122605.KB893637_gene3269	2.035e-54	209.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_3057662_0	1340493.JNIF01000003_gene2539	1.376e-114	374.0	COG2041@1|root,COG2041@2|Bacteria,3Y2X4@57723|Acidobacteria	2|Bacteria	S	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
GDHHQS2_k127_3057662_4	1123274.KB899420_gene4056	1.094e-05	48.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,2JAIQ@203691|Spirochaetes	203691|Spirochaetes	K	PFAM Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_AraC
GDHHQS2_k127_3057662_2	234267.Acid_7924	1.061e-35	144.0	2BMF1@1|root,32FZM@2|Bacteria,3Y8ZK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3057662_3	247490.KSU1_D0502	1.762e-10	68.0	COG3415@1|root,COG3415@2|Bacteria,2J51E@203682|Planctomycetes	203682|Planctomycetes	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS2_k127_3057662_1	1123248.KB893386_gene1855	1.768e-46	178.0	COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,1IQ2U@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_3057732_6	234267.Acid_4451	1.103e-105	357.0	COG0673@1|root,COG0673@2|Bacteria,3Y71T@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_3057732_11	525904.Tter_2376	6.679e-35	141.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33
GDHHQS2_k127_3057732_13	608506.COB47_0011	1.767e-07	58.0	2DR9X@1|root,33AUW@2|Bacteria,1VKEA@1239|Firmicutes	1239|Firmicutes	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
GDHHQS2_k127_3057732_2	261292.Nit79A3_3269	7.701e-162	521.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VZPE@28216|Betaproteobacteria,374NZ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase S8 S53, subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
GDHHQS2_k127_3057732_1	324602.Caur_1900	1.951e-181	584.0	COG1106@1|root,COG1106@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
GDHHQS2_k127_3057732_3	1340493.JNIF01000003_gene4590	2.425e-160	513.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_3057732_5	1267535.KB906767_gene4237	1.541e-134	441.0	COG0451@1|root,COG0451@2|Bacteria,3Y6G4@57723|Acidobacteria,2JM4D@204432|Acidobacteriia	204432|Acidobacteriia	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_3057732_9	234267.Acid_5266	2.318e-70	241.0	COG1839@1|root,COG1839@2|Bacteria,3Y7IR@57723|Acidobacteria	57723|Acidobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
GDHHQS2_k127_3057732_0	234267.Acid_5242	0.0	1016.0	COG0557@1|root,COG0557@2|Bacteria,3Y3TF@57723|Acidobacteria	57723|Acidobacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS2_k127_3057732_4	1267535.KB906767_gene3960	5.719e-148	488.0	COG1215@1|root,COG2804@1|root,COG1215@2|Bacteria,COG2804@2|Bacteria,3Y6KA@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,T2SSE_N
GDHHQS2_k127_3057732_8	1267535.KB906767_gene3361	5.939e-74	261.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS2_k127_3057732_7	1267535.KB906767_gene3360	1.033e-86	294.0	28JM9@1|root,2Z9DT@2|Bacteria,3Y2S6@57723|Acidobacteria,2JIQX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3065475_2	768671.ThimaDRAFT_3829	8.476e-88	296.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_8,RnfC_N,SLBB
GDHHQS2_k127_3065475_0	519989.ECTPHS_08968	0.0	2253.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
GDHHQS2_k127_3065475_1	768671.ThimaDRAFT_3827	7.521e-120	391.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales	135613|Chromatiales	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
GDHHQS2_k127_3065475_3	765912.Thimo_1753	3.341e-16	87.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1WWJF@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
GDHHQS2_k127_3066308_0	861299.J421_2250	5.834e-201	638.0	COG1435@1|root,COG1435@2|Bacteria	2|Bacteria	F	thymidine kinase activity	tdk	-	2.7.1.21	ko:K00857,ko:K21572	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB,TK
GDHHQS2_k127_3069139_0	1267535.KB906767_gene1639	9.394e-137	471.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3069139_1	1396418.BATQ01000137_gene3879	6.647e-52	199.0	2EZPI@1|root,33SUK@2|Bacteria,46TRK@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3072225_4	215803.DB30_4979	8.38e-54	211.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_3072225_6	1340493.JNIF01000003_gene3024	2.697e-24	109.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS2_k127_3072225_0	1038860.AXAP01000018_gene3108	1.713e-171	556.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_3072225_5	85643.Tmz1t_0047	7.937e-32	131.0	COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria,2VWUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_3072225_7	926550.CLDAP_40250	4.882e-14	80.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_3072225_1	1196031.ALEG01000005_gene5620	4.331e-154	501.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_3072225_2	290397.Adeh_2535	1.298e-104	351.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_3072225_3	1382306.JNIM01000001_gene2592	4.866e-64	225.0	COG1028@1|root,COG1028@2|Bacteria,2G8S6@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_3076453_1	521674.Plim_1708	3.601e-83	294.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_3076453_2	886293.Sinac_3596	1.63e-09	66.0	COG3295@1|root,COG3295@2|Bacteria,2IZY0@203682|Planctomycetes	203682|Planctomycetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3076453_0	518766.Rmar_2604	5.259e-175	556.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJZQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_3085715_1	171693.BN988_01982	3.773e-171	547.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,4ICAZ@91061|Bacilli,23K8G@182709|Oceanobacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_3085715_0	1340493.JNIF01000003_gene4529	3.859e-222	717.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3089224_1	1340493.JNIF01000003_gene2526	1.795e-92	317.0	COG1215@1|root,COG1215@2|Bacteria,3Y2JE@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
GDHHQS2_k127_3089224_3	234267.Acid_6449	6.338e-35	141.0	COG2510@1|root,COG2510@2|Bacteria,3Y549@57723|Acidobacteria	57723|Acidobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA,TMEM234
GDHHQS2_k127_3089224_7	1340493.JNIF01000003_gene2524	1.339e-23	106.0	COG2510@1|root,COG2510@2|Bacteria	2|Bacteria	EG	membrane	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
GDHHQS2_k127_3089224_0	234267.Acid_7504	2.502e-269	833.0	COG1032@1|root,COG1032@2|Bacteria,3Y2QU@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS2_k127_3089224_4	1267535.KB906767_gene2490	4.197e-33	149.0	COG5640@1|root,COG5640@2|Bacteria,3Y80T@57723|Acidobacteria	57723|Acidobacteria	O	endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3089224_6	1183438.GKIL_0813	4.286e-30	139.0	COG0265@1|root,COG3386@1|root,COG0265@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
GDHHQS2_k127_3089224_8	1340493.JNIF01000004_gene486	3.987e-17	97.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Autotransporter,PATR,Peptidase_S8
GDHHQS2_k127_3089224_5	1123073.KB899241_gene2586	2.056e-31	135.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
GDHHQS2_k127_3089224_2	234267.Acid_5462	1.904e-38	162.0	28NCT@1|root,2ZBFR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3089923_1	1340493.JNIF01000004_gene393	4.829e-114	377.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS2_k127_3089923_0	396588.Tgr7_0127	4.616e-167	545.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_3089923_2	1144343.PMI41_02642	9.014e-63	220.0	COG0702@1|root,COG0702@2|Bacteria,1QU1T@1224|Proteobacteria,2TTHK@28211|Alphaproteobacteria,43MYG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_3093551_7	1379698.RBG1_1C00001G0730	8.587e-12	68.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_3093551_4	1340493.JNIF01000004_gene334	2.343e-107	357.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_3093551_1	1340493.JNIF01000004_gene333	7.776e-220	694.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_3093551_0	234267.Acid_6445	0.0	1088.0	COG1615@1|root,COG1615@2|Bacteria,3Y6XA@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS2_k127_3093551_2	1267535.KB906767_gene1158	3.559e-194	614.0	COG0044@1|root,COG0044@2|Bacteria,3Y34R@57723|Acidobacteria,2JIA3@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_3093551_3	234267.Acid_5512	3.763e-139	447.0	COG0540@1|root,COG0540@2|Bacteria,3Y3KK@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS2_k127_3093551_5	234267.Acid_5511	8.51e-91	305.0	COG2065@1|root,COG2065@2|Bacteria,3Y2S1@57723|Acidobacteria	57723|Acidobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GDHHQS2_k127_3093551_6	886293.Sinac_2824	1.572e-77	266.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
GDHHQS2_k127_3098175_1	234267.Acid_1554	6.113e-79	269.0	COG0546@1|root,COG0546@2|Bacteria,3Y5BW@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_3098175_2	234267.Acid_1120	4.23e-47	181.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3098175_0	234267.Acid_1229	6.138e-203	643.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3098220_2	1267535.KB906767_gene968	3.282e-132	434.0	COG4591@1|root,COG4591@2|Bacteria,3Y3BU@57723|Acidobacteria,2JIC6@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3098220_0	204669.Acid345_1286	7.62e-194	616.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria,2JI1W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_3098220_4	1340493.JNIF01000003_gene2533	6.217e-123	402.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS2_k127_3098220_7	234267.Acid_1995	3.727e-77	272.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K11066,ko:K12287	-	-	-	-	ko00000,ko01000,ko01011,ko02044	-	-	-	Amidase_2
GDHHQS2_k127_3098220_8	234267.Acid_2465	3.971e-61	222.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3098220_5	234267.Acid_1853	3.225e-91	309.0	COG4464@1|root,COG4464@2|Bacteria,3Y4AS@57723|Acidobacteria	57723|Acidobacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS2_k127_3098220_13	1340493.JNIF01000003_gene1428	5.109e-28	117.0	COG4980@1|root,COG4980@2|Bacteria,3Y5IA@57723|Acidobacteria	57723|Acidobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS2_k127_3098220_11	1267535.KB906767_gene2099	2.27e-39	154.0	COG2137@1|root,COG2137@2|Bacteria,3Y4WT@57723|Acidobacteria	57723|Acidobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
GDHHQS2_k127_3098220_1	234267.Acid_1013	1.639e-154	494.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria	57723|Acidobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_3098220_14	977880.RALTA_B2196	2.079e-06	55.0	COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria,2WGXZ@28216|Betaproteobacteria,1KIR4@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
GDHHQS2_k127_3098220_6	1340493.JNIF01000003_gene2821	1.634e-88	297.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria	57723|Acidobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS2_k127_3098220_3	234267.Acid_1806	1.18e-129	430.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_3098220_9	234267.Acid_1805	2.293e-58	213.0	COG0457@1|root,COG0457@2|Bacteria,3Y5WJ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3098220_10	234267.Acid_1804	2.204e-39	153.0	COG0571@1|root,COG0571@2|Bacteria,3Y4M2@57723|Acidobacteria	57723|Acidobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS2_k127_3106212_2	234267.Acid_2556	7.656e-89	297.0	COG2252@1|root,COG2252@2|Bacteria,3Y2I3@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
GDHHQS2_k127_3106212_0	344747.PM8797T_03419	7.692e-182	588.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_3106212_1	1196323.ALKF01000197_gene2265	2.611e-110	374.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26R87@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_3106212_4	41431.PCC8801_1238	8.435e-12	70.0	COG4636@1|root,COG4636@2|Bacteria,1G569@1117|Cyanobacteria,3KKN7@43988|Cyanothece	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_3106212_3	1170562.Cal6303_5402	1.142e-15	85.0	COG4636@1|root,COG4636@2|Bacteria,1G1RW@1117|Cyanobacteria,1HM0U@1161|Nostocales	1117|Cyanobacteria	S	COGs COG4636 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_3106212_5	1288963.ADIS_1386	1.793e-08	59.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3108309_2	1340493.JNIF01000004_gene740	1.638e-144	461.0	COG0059@1|root,COG0059@2|Bacteria,3Y34M@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
GDHHQS2_k127_3108309_5	1267535.KB906767_gene2415	2.955e-77	266.0	COG0440@1|root,COG0440@2|Bacteria,3Y580@57723|Acidobacteria	57723|Acidobacteria	E	Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
GDHHQS2_k127_3108309_0	234267.Acid_0180	4.013e-299	927.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria	57723|Acidobacteria	EH	PFAM Thiamine pyrophosphate	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_3108309_9	1198114.AciX9_0019	2.186e-21	100.0	COG4636@1|root,COG4636@2|Bacteria,3Y7WQ@57723|Acidobacteria,2JN0R@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_3108309_4	1340493.JNIF01000003_gene3241	4.786e-86	288.0	COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS2_k127_3108309_1	1163617.SCD_n02434	2.153e-152	508.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	treY	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
GDHHQS2_k127_3108309_7	1267535.KB906767_gene3291	3.27e-35	136.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GDHHQS2_k127_3108309_8	1267535.KB906767_gene3292	2.035e-27	115.0	COG0858@1|root,COG0858@2|Bacteria,3Y4X8@57723|Acidobacteria	57723|Acidobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS2_k127_3108309_3	234267.Acid_5201	2.244e-122	402.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS2_k127_3108309_6	1340493.JNIF01000003_gene2874	7.866e-36	138.0	COG0407@1|root,COG0407@2|Bacteria,3Y44R@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS2_k127_3113975_0	1123503.KB908057_gene2389	4.916e-61	229.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1R5Z8@1224|Proteobacteria,2U3ZX@28211|Alphaproteobacteria,2KHUB@204458|Caulobacterales	204458|Caulobacterales	P	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_3122207_1	234267.Acid_4830	3.659e-12	68.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3122207_2	1236908.wNo_10320	1.215e-09	70.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria,47F95@766|Rickettsiales	766|Rickettsiales	O	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
GDHHQS2_k127_3122207_0	344747.PM8797T_29348	1.245e-17	85.0	COG2010@1|root,COG2010@2|Bacteria,2IXJK@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_3124219_3	314230.DSM3645_26619	1.468e-71	250.0	COG2267@1|root,COG2267@2|Bacteria,2IZJN@203682|Planctomycetes	203682|Planctomycetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_3124219_4	449447.MAE_59960	1.682e-36	151.0	COG0500@1|root,COG2226@2|Bacteria,1G364@1117|Cyanobacteria	1117|Cyanobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3124219_0	1267535.KB906767_gene929	8.743e-268	844.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria,2JI2P@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS2_k127_3124219_1	234267.Acid_3545	4.988e-221	696.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_3124219_2	1267535.KB906767_gene1747	2.329e-106	349.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_3140719_0	1267535.KB906767_gene1751	1.118e-216	678.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS2_k127_3140719_3	1340493.JNIF01000003_gene1947	4.887e-94	317.0	COG0657@1|root,COG0657@2|Bacteria,3Y44Z@57723|Acidobacteria	57723|Acidobacteria	I	Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS2_k127_3140719_5	945713.IALB_2696	6.985e-57	214.0	COG0642@1|root,COG2205@2|Bacteria	945713.IALB_2696|-	T	PhoQ Sensor	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
GDHHQS2_k127_3140719_4	1267533.KB906733_gene2988	8.789e-87	296.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3140719_6	649638.Trad_1357	5.945e-19	95.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	PE-PPE,VKG_Carbox
GDHHQS2_k127_3140719_7	706587.Desti_1948	1.022e-18	90.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
GDHHQS2_k127_3140719_1	234267.Acid_6605	1.397e-128	416.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS2_k127_3140719_2	234267.Acid_6604	1.82e-107	361.0	COG1413@1|root,COG1413@2|Bacteria,3Y6AH@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_3141161_2	1340493.JNIF01000003_gene4134	1.511e-192	615.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_3141161_0	1340493.JNIF01000003_gene4135	3.863e-238	742.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3141161_5	234267.Acid_0347	1.007e-95	328.0	COG4974@1|root,COG4974@2|Bacteria,3Y2VX@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_3141161_1	1267535.KB906767_gene4427	1.705e-197	624.0	COG1206@1|root,COG1206@2|Bacteria,3Y2KD@57723|Acidobacteria,2JIGU@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS2_k127_3141161_4	1185876.BN8_01995	5.207e-125	419.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_3141161_6	1267535.KB906767_gene4233	1.352e-56	210.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS2_k127_3141161_3	344747.PM8797T_18384	9.529e-130	427.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_3141161_8	1125971.ASJB01000083_gene1960	2.168e-11	71.0	COG2104@1|root,COG2104@2|Bacteria,2I1GV@201174|Actinobacteria,4E7EI@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_3141161_7	234267.Acid_4998	5.807e-35	136.0	COG2017@1|root,COG2017@2|Bacteria,3Y7G9@57723|Acidobacteria	57723|Acidobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
GDHHQS2_k127_3141240_3	313628.LNTAR_22304	2.307e-75	267.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_3141240_4	309801.trd_0539	1.76e-63	225.0	COG0819@1|root,COG0819@2|Bacteria,2G6ZB@200795|Chloroflexi,27Y87@189775|Thermomicrobia	189775|Thermomicrobia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	-	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
GDHHQS2_k127_3141240_0	234267.Acid_1018	3.284e-219	689.0	COG0312@1|root,COG0312@2|Bacteria,3Y2TY@57723|Acidobacteria	57723|Acidobacteria	H	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	CoaE,PmbA_TldD
GDHHQS2_k127_3141240_1	234267.Acid_0024	1.421e-176	584.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_3141240_2	926550.CLDAP_07830	1.025e-94	336.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_3141450_0	240016.ABIZ01000001_gene4141	4.195e-191	606.0	COG4102@1|root,COG4102@2|Bacteria,46USF@74201|Verrucomicrobia,2IVK7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3141450_2	575540.Isop_3116	1.63e-153	498.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3141450_1	1210884.HG799472_gene14852	3.484e-176	584.0	COG2010@1|root,COG2010@2|Bacteria,2IX85@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_3151716_0	1267535.KB906767_gene1536	1.628e-58	220.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3151716_1	1144310.PMI07_005783	7.742e-08	54.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
GDHHQS2_k127_3152036_2	1521187.JPIM01000048_gene92	1.646e-75	256.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,375KD@32061|Chloroflexia	32061|Chloroflexia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS2_k127_3152036_1	1123278.KB893615_gene5179	1.036e-162	535.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_3152036_0	1340493.JNIF01000003_gene1814	3.167e-184	616.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3153617_6	452637.Oter_4341	1.025e-105	355.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,46VH9@74201|Verrucomicrobia,3K8AT@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
GDHHQS2_k127_3153617_9	1499967.BAYZ01000171_gene5549	2.548e-71	256.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS2_k127_3153617_2	1340493.JNIF01000003_gene3546	1.434e-116	387.0	COG0628@1|root,COG0628@2|Bacteria,3Y4N5@57723|Acidobacteria	57723|Acidobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS2_k127_3153617_12	234267.Acid_7012	9.038e-40	154.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria	57723|Acidobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS2_k127_3153617_5	234267.Acid_7013	5.296e-107	364.0	COG1559@1|root,COG1559@2|Bacteria,3Y2RD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS2_k127_3153617_13	1340493.JNIF01000003_gene3542	2.059e-36	140.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3153617_0	926566.Terro_1493	0.0	1105.0	COG3696@1|root,COG3696@2|Bacteria,3Y3AQ@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
GDHHQS2_k127_3153617_10	1340493.JNIF01000003_gene4833	5.372e-63	233.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
GDHHQS2_k127_3153617_8	1340493.JNIF01000003_gene4832	3.642e-73	267.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
GDHHQS2_k127_3153617_3	1267535.KB906767_gene791	7.035e-110	361.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GDHHQS2_k127_3153617_4	1183438.GKIL_3395	4.008e-108	366.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_3153617_1	234267.Acid_1229	9.392e-187	595.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3153617_11	234267.Acid_1554	1.178e-62	223.0	COG0546@1|root,COG0546@2|Bacteria,3Y5BW@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_3153617_7	1340493.JNIF01000003_gene3565	5.425e-102	344.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3155454_0	234267.Acid_4737	8.68e-226	726.0	COG4932@1|root,COG4932@2|Bacteria,3Y73S@57723|Acidobacteria	2|Bacteria	M	PFAM Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
GDHHQS2_k127_3155454_1	864069.MicloDRAFT_00004300	2.863e-11	68.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_23,HTH_Tnp_4,rve
GDHHQS2_k127_315880_1	330214.NIDE3619	1.797e-54	194.0	29KDN@1|root,307AY@2|Bacteria,3J14Y@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_315880_0	296591.Bpro_1676	1.295e-118	386.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_3160721_8	1403819.BATR01000181_gene6201	2.972e-19	89.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_3160721_7	269799.Gmet_2804	1.406e-63	229.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_3160721_2	1267535.KB906767_gene2632	3.269e-147	479.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS2_k127_3160721_4	1304866.K413DRAFT_2232	4.459e-89	303.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,36DKV@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_3160721_3	1340493.JNIF01000004_gene376	1.149e-145	474.0	COG0707@1|root,COG0707@2|Bacteria,3Y651@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 28 C-terminal domain	-	-	2.4.1.46	ko:K03715	ko00561,ko01100,map00561,map01100	-	R02691	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C
GDHHQS2_k127_3160721_1	234267.Acid_3444	4.744e-151	511.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_3160721_6	234267.Acid_4335	5.429e-69	238.0	COG0671@1|root,COG0671@2|Bacteria,3Y5XF@57723|Acidobacteria	57723|Acidobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_3160721_0	234267.Acid_4936	7.465e-247	788.0	COG2366@1|root,COG2366@2|Bacteria,3Y2PX@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_3160721_5	1267535.KB906767_gene517	9.503e-74	257.0	COG1253@1|root,COG1253@2|Bacteria,3Y2KE@57723|Acidobacteria,2JHJ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_3161863_0	234267.Acid_1620	2.16e-150	499.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,PEGA,Plug,TonB_dep_Rec
GDHHQS2_k127_3164088_10	530564.Psta_1970	2.919e-17	89.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXCI@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS2_k127_3164088_2	1340493.JNIF01000003_gene2091	9.588e-170	550.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_3164088_4	1131814.JAFO01000001_gene1007	1.768e-83	296.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3EZXA@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_3164088_13	1206732.BAGD01000084_gene3620	0.0004318	53.0	COG3920@1|root,COG3920@2|Bacteria,2HFG8@201174|Actinobacteria,4G5I5@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS
GDHHQS2_k127_3164088_11	1123508.JH636442_gene4367	1.643e-15	90.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS2_k127_3164088_0	234267.Acid_6385	6.899e-216	694.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_3164088_9	1123377.AUIV01000001_gene1014	2.137e-17	87.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,1X5PX@135614|Xanthomonadales	135614|Xanthomonadales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
GDHHQS2_k127_3164088_7	339670.Bamb_4784	3.381e-46	173.0	2B7JP@1|root,320QE@2|Bacteria,1RHGR@1224|Proteobacteria,2WE3W@28216|Betaproteobacteria,1KBKW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS2_k127_3164088_8	1210884.HG799466_gene13044	2.076e-41	155.0	COG1403@1|root,COG1403@2|Bacteria,2J3RR@203682|Planctomycetes	203682|Planctomycetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GDHHQS2_k127_3164088_3	870187.Thini_2418	4.025e-86	300.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,461CN@72273|Thiotrichales	72273|Thiotrichales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
GDHHQS2_k127_3164088_6	344747.PM8797T_04085	2.984e-47	193.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
GDHHQS2_k127_3164088_1	234267.Acid_1183	2.869e-191	617.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y6RM@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
GDHHQS2_k127_3164088_5	1267535.KB906767_gene5503	6.63e-56	200.0	COG0684@1|root,COG0684@2|Bacteria,3Y8I2@57723|Acidobacteria	57723|Acidobacteria	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS2_k127_3165838_8	1340493.JNIF01000003_gene3891	5.161e-19	95.0	COG1714@1|root,COG1714@2|Bacteria,3Y5I9@57723|Acidobacteria	57723|Acidobacteria	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS2_k127_3165838_0	1340493.JNIF01000003_gene3892	2.578e-268	850.0	COG1452@1|root,COG1452@2|Bacteria,3Y37B@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
GDHHQS2_k127_3165838_7	525904.Tter_2267	1.775e-34	134.0	COG4948@1|root,COG4948@2|Bacteria,2NQCI@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	rspA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_3165838_6	1442599.JAAN01000013_gene3673	3.583e-35	145.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1X5A0@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_3165838_9	1340493.JNIF01000004_gene448	0.0002093	49.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_3165838_3	404589.Anae109_3061	2.874e-61	218.0	COG5522@1|root,COG5522@2|Bacteria,1QM2T@1224|Proteobacteria,435G9@68525|delta/epsilon subdivisions,2WZTR@28221|Deltaproteobacteria,2Z2QR@29|Myxococcales	28221|Deltaproteobacteria	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
GDHHQS2_k127_3165838_1	234267.Acid_7543	3.133e-126	414.0	COG0823@1|root,COG0823@2|Bacteria,3Y6DB@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_3165838_4	1267535.KB906767_gene543	4.424e-58	209.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria,2JJBS@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_3165838_2	234267.Acid_4190	4.396e-99	333.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_3165838_5	344747.PM8797T_25641	4.821e-51	190.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_3165850_2	1340493.JNIF01000003_gene1755	1.245e-83	283.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3165850_4	1304880.JAGB01000005_gene2466	9.07e-26	112.0	COG1661@1|root,COG1661@2|Bacteria,1V67W@1239|Firmicutes,24J3Y@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
GDHHQS2_k127_3165850_0	1379270.AUXF01000005_gene474	5.817e-129	436.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_3165850_1	1151127.KB906327_gene1641	1.772e-90	309.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,1SYCA@1236|Gammaproteobacteria,1YM3T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	C	NADPH quinone	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_3165850_3	240016.ABIZ01000001_gene2574	1.211e-47	178.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_3165850_5	1267533.KB906738_gene2389	9.952e-24	115.0	COG1609@1|root,COG1609@2|Bacteria,3Y423@57723|Acidobacteria,2JHRM@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_3165850_6	929506.CbC4_0688	5.372e-06	58.0	2DZRA@1|root,32VGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_3175594_0	1340493.JNIF01000003_gene1762	7.653e-254	787.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS2_k127_3175594_1	1408473.JHXO01000007_gene826	1.278e-05	56.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
GDHHQS2_k127_3177581_2	1192034.CAP_0209	1.851e-06	52.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2Z3JD@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_3177581_3	90675.XP_010513122.1	0.0001846	53.0	COG4886@1|root,KOG0619@2759|Eukaryota,37IH3@33090|Viridiplantae,3GVCI@35493|Streptophyta,3HZT0@3699|Brassicales	35493|Streptophyta	L	Receptor-like protein 12	-	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_6,LRR_8
GDHHQS2_k127_3177581_1	264201.pc1915	5.652e-32	145.0	COG4886@1|root,COG4886@2|Bacteria,2JGIV@204428|Chlamydiae	204428|Chlamydiae	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTB,LRR_1,LRR_6
GDHHQS2_k127_3177581_0	1340493.JNIF01000003_gene4293	2.475e-34	139.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3185338_0	211165.AJLN01000048_gene6000	1.83e-33	149.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_3185338_1	1268237.G114_08315	2.631e-07	64.0	COG3850@1|root,COG4251@1|root,COG3850@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_3187770_0	1340493.JNIF01000003_gene3565	3.751e-99	335.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3187770_1	247634.GPB2148_2290	5.899e-05	51.0	COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ydaM	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016740,GO:0016772,GO:0016779,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043900,GO:0043902,GO:0044093,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051252,GO:0052621,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1903506,GO:2000112,GO:2001141	2.7.7.65	ko:K19707,ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko03021	-	-	-	GGDEF,PAS_4,PAS_8,PAS_9
GDHHQS2_k127_3187920_4	856793.MICA_429	7.301e-16	88.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2U30N@28211|Alphaproteobacteria,4BQQV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
GDHHQS2_k127_3187920_0	401053.AciPR4_1439	8.531e-273	879.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3187920_2	234267.Acid_4915	1.277e-99	332.0	COG0584@1|root,COG0584@2|Bacteria,3Y40Q@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS2_k127_3187920_1	1340493.JNIF01000003_gene2854	2.618e-198	626.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_3187920_3	1340493.JNIF01000003_gene2855	5.354e-90	305.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
GDHHQS2_k127_3188413_2	234267.Acid_5906	5.445e-54	192.0	COG0451@1|root,COG0451@2|Bacteria,3Y3ZG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_3188413_5	1121935.AQXX01000089_gene4689	4.965e-07	54.0	2EKSU@1|root,33EGJ@2|Bacteria,1PN54@1224|Proteobacteria,1SH7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
GDHHQS2_k127_3188413_3	172088.AUGA01000014_gene3089	2.645e-43	166.0	COG5446@1|root,COG5446@2|Bacteria,1RBWQ@1224|Proteobacteria,2U9NN@28211|Alphaproteobacteria,3JTIZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Probable cobalt transporter subunit (CbtA)	cbtA	-	-	-	-	-	-	-	-	-	-	-	CbtA
GDHHQS2_k127_3188413_1	526225.Gobs_3778	1.042e-62	226.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4ERX7@85013|Frankiales	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase,RraA-like
GDHHQS2_k127_3188413_6	128390.XP_009472021.1	2.506e-06	60.0	COG1073@1|root,2QQ8Z@2759|Eukaryota,38H36@33154|Opisthokonta,3BEH7@33208|Metazoa,3CR64@33213|Bilateria,481P8@7711|Chordata,48ZNE@7742|Vertebrata,4GPTH@8782|Aves	33208|Metazoa	S	Acyl-coenzyme A thioesterase	ACOT4	GO:0000038,GO:0001666,GO:0001676,GO:0003674,GO:0003824,GO:0004778,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006104,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0031667,GO:0031907,GO:0031974,GO:0032787,GO:0032788,GO:0032789,GO:0033036,GO:0033365,GO:0033865,GO:0033875,GO:0034032,GO:0034613,GO:0034641,GO:0035383,GO:0036293,GO:0042221,GO:0042493,GO:0042579,GO:0042760,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046459,GO:0046483,GO:0046907,GO:0047617,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051641,GO:0051649,GO:0055086,GO:0070013,GO:0070482,GO:0070727,GO:0070848,GO:0070849,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072521,GO:0072594,GO:0072662,GO:0072663,GO:1901135,GO:1901360,GO:1901564,GO:1901575	2.3.1.65,3.1.2.2	ko:K00659,ko:K01068,ko:K11993	ko00062,ko00120,ko00430,ko01040,ko01100,ko01110,ko04146,ko04976,map00062,map00120,map00430,map01040,map01100,map01110,map04146,map04976	M00106	R01274,R03718,R03720,R08174,R08175,R08176,R08177,R08178,R08179,R08180,R08181,R08182,R08183,R08744,R08745,R09450	RC00004,RC00014,RC00096,RC02867	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	BAAT_C,Bile_Hydr_Trans
GDHHQS2_k127_3188413_0	1340493.JNIF01000004_gene356	1.883e-108	355.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
GDHHQS2_k127_3188413_4	1340493.JNIF01000004_gene626	1.106e-09	64.0	COG1629@1|root,COG4771@2|Bacteria,3Y6GV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3188413_7	234267.Acid_5753	0.000737	48.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3201304_2	1267535.KB906767_gene1323	1.262e-25	109.0	COG2346@1|root,COG2346@2|Bacteria,3Y8TC@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS2_k127_3201304_0	497964.CfE428DRAFT_5254	7.242e-86	291.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS2_k127_3201304_1	1340493.JNIF01000004_gene228	6.256e-49	186.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_3201304_3	1123322.KB904744_gene3428	4.515e-18	83.0	COG0329@1|root,COG0329@2|Bacteria,2GK87@201174|Actinobacteria	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
GDHHQS2_k127_3211325_4	1267535.KB906767_gene1461	2.08e-10	63.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
GDHHQS2_k127_3211325_2	1267535.KB906767_gene1462	4.182e-117	384.0	COG1131@1|root,COG1131@2|Bacteria,3Y7J3@57723|Acidobacteria,2JMS8@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3211325_0	886293.Sinac_1613	8.727e-127	422.0	COG2234@1|root,COG2234@2|Bacteria,2J3AQ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_3211325_1	1340493.JNIF01000003_gene2877	2.151e-125	419.0	COG0666@1|root,COG0666@2|Bacteria,3Y6UE@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
GDHHQS2_k127_3211325_3	886293.Sinac_6627	2.282e-17	87.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4
GDHHQS2_k127_3222812_1	887062.HGR_10957	2.666e-70	245.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2VM0Y@28216|Betaproteobacteria,4ABR8@80864|Comamonadaceae	28216|Betaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS2_k127_3222812_2	1003200.AXXA_01723	3.878e-32	130.0	COG0319@1|root,COG0319@2|Bacteria,1QU0Q@1224|Proteobacteria,2VSPI@28216|Betaproteobacteria,3T7M5@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3225)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3225
GDHHQS2_k127_3222812_3	195250.CM001776_gene1987	2.96e-22	100.0	COG4876@1|root,COG4876@2|Bacteria,1GFS6@1117|Cyanobacteria	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
GDHHQS2_k127_3222812_0	340177.Cag_0427	1.234e-78	267.0	2AP2K@1|root,31E40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_322402_1	471854.Dfer_0798	1.096e-102	357.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47KSM@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_322402_2	428125.CLOLEP_02216	4.61e-74	257.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,24BBC@186801|Clostridia,3WRPI@541000|Ruminococcaceae	186801|Clostridia	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.69	ko:K00046,ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_322402_0	1288963.ADIS_1775	2.647e-176	565.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_322402_3	234267.Acid_2826	5.67e-46	169.0	COG0537@1|root,COG0537@2|Bacteria,3Y542@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS2_k127_3226693_0	1267535.KB906767_gene97	5.701e-163	520.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_3226693_1	535289.Dtpsy_1328	9.734e-125	407.0	COG2253@1|root,COG2253@2|Bacteria,1PZRM@1224|Proteobacteria,2VPSW@28216|Betaproteobacteria,4AEPT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS2_k127_3226693_3	543728.Vapar_1918	1.668e-71	247.0	COG5340@1|root,COG5340@2|Bacteria,1R1GM@1224|Proteobacteria,2VRV9@28216|Betaproteobacteria,4AEA8@80864|Comamonadaceae	28216|Betaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
GDHHQS2_k127_3226693_2	234267.Acid_5899	1.708e-83	299.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS2_k127_3226693_4	502025.Hoch_4953	2.435e-13	72.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2WRKF@28221|Deltaproteobacteria,2YV99@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS2_k127_3227347_1	1415779.JOMH01000001_gene730	3.332e-05	56.0	COG0789@1|root,COG0789@2|Bacteria,1N7M7@1224|Proteobacteria,1T88N@1236|Gammaproteobacteria,1XAA5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_3227347_0	204669.Acid345_0501	2.921e-109	360.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_3228412_3	102129.Lepto7375DRAFT_2608	5.188e-70	242.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	ampD	-	3.5.1.28	ko:K01447,ko:K03806,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1,SH3_3
GDHHQS2_k127_3228412_2	439375.Oant_3913	6.376e-81	281.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,1J3UU@118882|Brucellaceae	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_3228412_1	1267535.KB906767_gene3548	9.408e-116	383.0	COG1420@1|root,COG1420@2|Bacteria,3Y2JI@57723|Acidobacteria,2JI0D@204432|Acidobacteriia	204432|Acidobacteriia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
GDHHQS2_k127_3228412_4	234267.Acid_0733	5.452e-50	183.0	COG0576@1|root,COG0576@2|Bacteria,3Y54K@57723|Acidobacteria	57723|Acidobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS2_k127_3228412_0	234267.Acid_0734	2.039e-141	457.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_3232288_2	1267535.KB906767_gene4836	1e-68	239.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene4836|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3232288_0	1340493.JNIF01000003_gene2517	0.0	1565.0	COG1629@1|root,COG4771@2|Bacteria,3Y3NM@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3232288_1	234267.Acid_7415	2.038e-300	959.0	COG3188@1|root,COG3188@2|Bacteria,3Y42P@57723|Acidobacteria	57723|Acidobacteria	NU	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3244316_0	1340493.JNIF01000003_gene1814	5.276e-112	397.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3244316_1	639030.JHVA01000001_gene1924	2.11e-13	76.0	COG3118@1|root,COG3118@2|Bacteria,3Y69N@57723|Acidobacteria,2JMI3@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_3253381_0	1340493.JNIF01000003_gene2841	5.914e-231	720.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_3253381_11	1340493.JNIF01000004_gene749	9.07e-41	159.0	2FHEK@1|root,3498P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3253381_2	1267535.KB906767_gene838	5.268e-191	606.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_3253381_6	1340493.JNIF01000003_gene1919	9.356e-130	437.0	COG5000@1|root,COG5000@2|Bacteria,3Y32Z@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_3253381_12	1340493.JNIF01000003_gene1921	3.975e-30	132.0	COG2885@1|root,COG2885@2|Bacteria,3Y425@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_3253381_14	234267.Acid_4627	2.869e-13	82.0	COG2199@1|root,COG2199@2|Bacteria,3Y6RG@57723|Acidobacteria	57723|Acidobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS2_k127_3253381_10	1340493.JNIF01000003_gene1333	1.642e-76	277.0	COG4963@1|root,COG4963@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
GDHHQS2_k127_3253381_13	521674.Plim_0814	1.398e-29	123.0	COG0802@1|root,COG0802@2|Bacteria	2|Bacteria	S	tRNA threonylcarbamoyladenosine modification	yjeE	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
GDHHQS2_k127_3253381_3	234267.Acid_2158	5.473e-176	573.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3Y3XN@57723|Acidobacteria	57723|Acidobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GDHHQS2_k127_3253381_7	234267.Acid_2751	1.088e-115	381.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,3Y4K4@57723|Acidobacteria	57723|Acidobacteria	P	TrkA-C domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
GDHHQS2_k127_3253381_4	1340493.JNIF01000003_gene2275	2.39e-155	512.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,3Y2P9@57723|Acidobacteria	57723|Acidobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
GDHHQS2_k127_3253381_8	1340493.JNIF01000003_gene2276	4.651e-110	362.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria	57723|Acidobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_3253381_5	234267.Acid_3589	5.186e-147	472.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS2_k127_3253381_9	1340493.JNIF01000003_gene1459	1.193e-103	351.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	lprD	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	HlyD_3
GDHHQS2_k127_3253381_1	861299.J421_5946	3.25e-204	657.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_3267623_4	234267.Acid_0789	2.721e-16	81.0	COG3595@1|root,COG3595@2|Bacteria,3Y3K3@57723|Acidobacteria	57723|Acidobacteria	C	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_3267623_3	234267.Acid_0791	1.256e-46	177.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
GDHHQS2_k127_3267623_2	234267.Acid_0792	8.662e-52	190.0	COG5662@1|root,COG5662@2|Bacteria,3Y4S0@57723|Acidobacteria	57723|Acidobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_3267623_0	1267535.KB906767_gene1043	1.822e-85	288.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_3267623_1	234267.Acid_0794	2.704e-71	252.0	COG0392@1|root,COG0392@2|Bacteria,3Y3SG@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_3277506_4	1340493.JNIF01000003_gene2881	1.915e-100	333.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria	57723|Acidobacteria	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
GDHHQS2_k127_3277506_15	575540.Isop_3691	3.718e-07	62.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW	-	-	ko:K02659,ko:K03408,ko:K03415,ko:K11524	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	CheW
GDHHQS2_k127_3277506_1	575540.Isop_3690	7.246e-174	586.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,2IWWG@203682|Planctomycetes	203682|Planctomycetes	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
GDHHQS2_k127_3277506_3	575540.Isop_3689	1.913e-110	384.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,2IXQA@203682|Planctomycetes	203682|Planctomycetes	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Globin,HAMP,MCPsignal,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_3277506_13	645991.Sgly_0591	4.328e-16	91.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,261WX@186807|Peptococcaceae	186801|Clostridia	NT	Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_3277506_10	575540.Isop_3677	1.367e-34	136.0	COG0745@1|root,COG0745@2|Bacteria,2J342@203682|Planctomycetes	203682|Planctomycetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_3277506_11	575540.Isop_3686	4.802e-33	144.0	COG2199@1|root,COG3706@2|Bacteria,2J3IY@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_3277506_7	234267.Acid_0123	1.224e-84	285.0	COG2096@1|root,COG2096@2|Bacteria,3Y77H@57723|Acidobacteria	57723|Acidobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS2_k127_3277506_12	1121456.ATVA01000011_gene1441	5.416e-24	109.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
GDHHQS2_k127_3277506_14	234267.Acid_2149	2.028e-09	63.0	COG0612@1|root,COG0612@2|Bacteria,3Y79G@57723|Acidobacteria	57723|Acidobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_3277506_16	234267.Acid_2149	8.278e-06	48.0	COG0612@1|root,COG0612@2|Bacteria,3Y79G@57723|Acidobacteria	57723|Acidobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_3277506_9	869209.Tresu_1492	7.858e-36	147.0	COG1864@1|root,COG1864@2|Bacteria,2J7IP@203691|Spirochaetes	203691|Spirochaetes	V	DNA RNA non-specific endonuclease	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_3277506_0	234267.Acid_7927	0.0	1110.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS2_k127_3277506_5	204669.Acid345_3369	1.101e-92	337.0	COG0515@1|root,COG0515@2|Bacteria	204669.Acid345_3369|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_3277506_2	204669.Acid345_4150	1.402e-112	375.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3277506_8	1340493.JNIF01000004_gene504	7.686e-79	270.0	COG0705@1|root,COG0705@2|Bacteria,3Y45U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_3277506_6	204669.Acid345_4155	7.651e-85	300.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_3292771_0	234267.Acid_7415	1.099e-291	931.0	COG3188@1|root,COG3188@2|Bacteria,3Y42P@57723|Acidobacteria	57723|Acidobacteria	NU	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3297324_0	452637.Oter_0312	4.288e-49	192.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
GDHHQS2_k127_3297324_1	1121403.AUCV01000012_gene4109	3.849e-34	147.0	COG1075@1|root,COG1075@2|Bacteria,1QD4I@1224|Proteobacteria,435MR@68525|delta/epsilon subdivisions,2X9BC@28221|Deltaproteobacteria,2MNSY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3297324_2	1215092.PA6_002_00780	0.0002508	50.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria	1224|Proteobacteria	M	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
GDHHQS2_k127_3306710_2	1340493.JNIF01000003_gene1982	6.356e-23	100.0	COG3127@1|root,COG3127@2|Bacteria,3Y2PA@57723|Acidobacteria	57723|Acidobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3306710_0	240015.ACP_0895	6.726e-93	311.0	COG4181@1|root,COG4181@2|Bacteria,3Y3RU@57723|Acidobacteria,2JI42@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3306710_1	234267.Acid_1431	5.334e-74	258.0	COG0451@1|root,COG0451@2|Bacteria,3Y2P2@57723|Acidobacteria	2|Bacteria	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GDHHQS2_k127_330708_0	234267.Acid_7568	7.229e-188	599.0	COG0841@1|root,COG0841@2|Bacteria,3Y2RX@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_330708_1	1340493.JNIF01000003_gene2396	1.637e-81	299.0	COG1538@1|root,COG1538@2|Bacteria,3Y3JU@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_330708_2	639030.JHVA01000001_gene1877	1.24e-33	136.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_333102_3	1340493.JNIF01000003_gene2857	4.046e-67	238.0	COG4254@1|root,COG4254@2|Bacteria,3Y90P@57723|Acidobacteria	57723|Acidobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS2_k127_333102_0	234267.Acid_6368	2.568e-148	491.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GDHHQS2_k127_333102_4	234267.Acid_7286	9.777e-64	224.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_333102_1	1123242.JH636434_gene3309	5.682e-102	341.0	COG1028@1|root,COG1028@2|Bacteria,2IWS4@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_333102_5	1183438.GKIL_1638	5.886e-39	156.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	3.4.19.5	ko:K03088,ko:K13051	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	DUF4440,SnoaL_3
GDHHQS2_k127_333102_6	555779.Dthio_PD1689	0.0006373	44.0	COG1848@1|root,COG1848@2|Bacteria,1N5KS@1224|Proteobacteria,42UG5@68525|delta/epsilon subdivisions,2WQVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_333102_2	234267.Acid_3448	1.894e-75	258.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_3332352_7	234267.Acid_1542	8.865e-24	102.0	COG1131@1|root,COG1131@2|Bacteria,3Y394@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3332352_2	1340493.JNIF01000003_gene4798	4.763e-102	354.0	2EM41@1|root,33ETI@2|Bacteria,3Y97X@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3332352_4	234267.Acid_1039	7.626e-44	164.0	COG1648@1|root,COG1648@2|Bacteria,3Y4XH@57723|Acidobacteria	57723|Acidobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
GDHHQS2_k127_3332352_10	195250.CM001776_gene2136	1.388e-10	64.0	COG1813@1|root,COG1813@2|Bacteria	2|Bacteria	K	peptidyl-tyrosine sulfation	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,HTH_31
GDHHQS2_k127_3332352_11	489825.LYNGBM3L_67290	2.534e-09	63.0	2FFTH@1|root,347QN@2|Bacteria,1GFHM@1117|Cyanobacteria,1HGA0@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3332352_0	886293.Sinac_7090	1.126e-152	523.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3332352_3	234267.Acid_0487	1.936e-70	260.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GDHHQS2_k127_3332352_8	234267.Acid_3958	5.672e-19	93.0	299QU@1|root,2ZWT2@2|Bacteria,3Y915@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3332352_5	1232410.KI421412_gene406	6.76e-29	132.0	COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria	1224|Proteobacteria	L	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3332352_1	1183438.GKIL_3395	9.058e-148	504.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_3333807_5	1128912.GMES_3896	5.552e-21	94.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPM3@1236|Gammaproteobacteria,46DHH@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	ydeN	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_3333807_4	234267.Acid_3880	1.069e-26	118.0	COG1225@1|root,COG1225@2|Bacteria,3Y8N3@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_3333807_2	234267.Acid_3879	1.276e-79	268.0	COG1143@1|root,COG1143@2|Bacteria,3Y371@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
GDHHQS2_k127_3333807_6	1279019.ARQK01000058_gene744	4.669e-08	65.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
GDHHQS2_k127_3333807_3	926550.CLDAP_18150	6.92e-28	123.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
GDHHQS2_k127_3333807_1	713586.KB900536_gene1341	2.313e-169	539.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
GDHHQS2_k127_3333807_0	1158150.KB906246_gene1915	2.398e-185	588.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GDHHQS2_k127_3335579_1	518766.Rmar_2392	7.195e-06	53.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3335579_0	903818.KI912268_gene893	7.264e-200	629.0	COG1038@1|root,COG1038@2|Bacteria,3Y6UX@57723|Acidobacteria	57723|Acidobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
GDHHQS2_k127_3364180_0	234267.Acid_5147	7.069e-195	616.0	COG2768@1|root,COG2768@2|Bacteria,3Y61G@57723|Acidobacteria	57723|Acidobacteria	C	binding domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3366008_4	1342302.JASC01000013_gene2937	1.136e-80	282.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,3ZWPH@60136|Sulfitobacter	28211|Alphaproteobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_3366008_13	1146883.BLASA_2817	5.4e-11	73.0	2E6FA@1|root,3312Q@2|Bacteria,2GUWJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3366008_12	228405.HNE_2485	1.204e-16	82.0	2E6FA@1|root,3312Q@2|Bacteria,1NCPQ@1224|Proteobacteria,2UKWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3366008_9	99598.Cal7507_2948	5.125e-32	129.0	COG3744@1|root,COG3744@2|Bacteria,1G9VS@1117|Cyanobacteria,1HQ0Y@1161|Nostocales	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_3366008_5	1340493.JNIF01000003_gene3734	1.949e-79	269.0	COG0221@1|root,COG0221@2|Bacteria,3Y3UZ@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
GDHHQS2_k127_3366008_1	234267.Acid_7929	2.448e-95	317.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_3366008_11	234267.Acid_7930	9.738e-18	89.0	2DYZH@1|root,34BW9@2|Bacteria,3Y8R9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3366008_3	1267535.KB906767_gene2144	7.55e-87	303.0	COG0354@1|root,COG0354@2|Bacteria,3Y2PI@57723|Acidobacteria,2JJ3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_3366008_10	204669.Acid345_0930	1.586e-20	104.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria,2JM3F@204432|Acidobacteriia	204432|Acidobacteriia	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS2_k127_3366008_0	1267535.KB906767_gene2552	0.0	1177.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria,2JMMF@204432|Acidobacteriia	204432|Acidobacteriia	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_3366008_6	926560.KE387023_gene2884	9.331e-61	214.0	COG2318@1|root,COG2318@2|Bacteria,1WMM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_3366008_7	1267535.KB906767_gene486	1.409e-60	215.0	COG5649@1|root,COG5649@2|Bacteria,3Y4MQ@57723|Acidobacteria,2JJV2@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_3366008_8	234267.Acid_3038	1.455e-58	207.0	COG2259@1|root,32Z45@2|Bacteria	2|Bacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
GDHHQS2_k127_3366008_2	404589.Anae109_1064	3.601e-95	314.0	COG3832@1|root,COG3832@2|Bacteria,1RB7X@1224|Proteobacteria,433Y9@68525|delta/epsilon subdivisions,2X420@28221|Deltaproteobacteria,2YY0C@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_336697_1	234267.Acid_2974	3.097e-213	704.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_336697_2	1340493.JNIF01000003_gene2971	1.08e-159	515.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
GDHHQS2_k127_336697_0	1000565.METUNv1_03363	3.572e-270	848.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
GDHHQS2_k127_336697_4	204669.Acid345_2012	3.461e-25	113.0	29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria,2JMXT@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_336697_5	313596.RB2501_11522	4.72e-25	116.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1HYD5@117743|Flavobacteriia	976|Bacteroidetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
GDHHQS2_k127_336697_3	234267.Acid_5869	1.385e-67	245.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_336791_1	518766.Rmar_1256	6.766e-42	160.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1FJ56@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_336791_0	378806.STAUR_5497	3.302e-231	726.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2YY8V@29|Myxococcales	28221|Deltaproteobacteria	CJ	CoA binding domain	acs	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GDHHQS2_k127_3371894_3	1121924.ATWH01000005_gene2619	4.795e-06	54.0	COG1807@1|root,COG5492@1|root,COG1807@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Metallophos,NAGPA,PCMD,Pur_ac_phosph_N,SLH
GDHHQS2_k127_3371894_0	234267.Acid_4756	0.0	1270.0	COG0013@1|root,COG0013@2|Bacteria,3Y359@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS2_k127_3371894_1	234267.Acid_4757	1.468e-148	485.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria	57723|Acidobacteria	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GDHHQS2_k127_3371894_2	234267.Acid_7548	7.224e-103	342.0	COG1453@1|root,COG1453@2|Bacteria,3Y6QH@57723|Acidobacteria	57723|Acidobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_3378448_2	1340493.JNIF01000003_gene2565	1.743e-57	203.0	COG3842@1|root,COG3842@2|Bacteria,3Y4Q4@57723|Acidobacteria	57723|Acidobacteria	P	TOBE domain	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_3378448_0	234267.Acid_2368	1.551e-108	357.0	COG1176@1|root,COG1176@2|Bacteria,3Y531@57723|Acidobacteria	57723|Acidobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_3378448_1	1340493.JNIF01000003_gene2567	1.361e-97	330.0	COG1177@1|root,COG1177@2|Bacteria,3Y57S@57723|Acidobacteria	57723|Acidobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_3378448_3	234267.Acid_2370	7.038e-13	72.0	COG0687@1|root,COG0687@2|Bacteria,3Y5JD@57723|Acidobacteria	57723|Acidobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS2_k127_3397626_0	234267.Acid_7841	1.491e-206	670.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3397626_1	479435.Kfla_1654	3.384e-74	257.0	COG1708@1|root,COG1708@2|Bacteria,2IFWR@201174|Actinobacteria,4DV9C@85009|Propionibacteriales	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS2_k127_3397626_2	179408.Osc7112_6189	3.396e-46	190.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GDHHQS2_k127_340611_8	1210884.HG799469_gene14063	2.467e-17	84.0	COG2010@1|root,COG2010@2|Bacteria,2IXBQ@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_340611_0	1340493.JNIF01000003_gene3903	8.577e-191	606.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_340611_9	755178.Cyan10605_3514	4.666e-08	56.0	COG4679@1|root,COG4679@2|Bacteria,1G6SB@1117|Cyanobacteria	1117|Cyanobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_340611_7	886293.Sinac_7503	7.229e-30	122.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,HTH_37
GDHHQS2_k127_340611_1	234267.Acid_3424	1.008e-182	586.0	COG1070@1|root,COG1070@2|Bacteria,3Y2YC@57723|Acidobacteria	57723|Acidobacteria	G	PFAM carbohydrate kinase	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_340611_3	1267534.KB906760_gene1575	5.867e-69	246.0	COG1063@1|root,COG1063@2|Bacteria,3Y6GC@57723|Acidobacteria	57723|Acidobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_340611_5	234267.Acid_5838	1.485e-40	157.0	COG2606@1|root,COG2606@2|Bacteria,3Y54I@57723|Acidobacteria	57723|Acidobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS2_k127_340611_4	1122176.KB903546_gene1029	5.21e-57	219.0	COG1572@1|root,COG4733@1|root,COG1572@2|Bacteria,COG4733@2|Bacteria,4NQCQ@976|Bacteroidetes,1J03U@117747|Sphingobacteriia	976|Bacteroidetes	S	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
GDHHQS2_k127_340611_2	234267.Acid_4215	1.113e-94	316.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_3410526_0	1267535.KB906767_gene738	9.465e-76	265.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria,2JI2M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3410526_1	682795.AciX8_3228	1.061e-40	165.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_3411070_4	1321781.HMPREF1985_01462	5.419e-09	57.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,4H24Q@909932|Negativicutes	909932|Negativicutes	G	Transketolase, thiamine diphosphate binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS2_k127_3411070_3	448385.sce5406	6.369e-12	79.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,KAP_NTPase
GDHHQS2_k127_3411070_1	1123242.JH636434_gene3349	1.651e-101	356.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	2|Bacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	DNA_pol_A_exo1,FtsK_SpoIIIE,PDDEXK_1
GDHHQS2_k127_3411070_2	696747.NIES39_C05180	1.617e-20	102.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
GDHHQS2_k127_3411070_0	234267.Acid_2349	7.298e-144	467.0	COG2271@1|root,COG2271@2|Bacteria,3Y7EW@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_3413016_0	1161401.ASJA01000002_gene2633	1.39e-263	829.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,43X0I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
GDHHQS2_k127_3413016_1	404589.Anae109_4095	8.338e-88	309.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_3413016_3	323261.Noc_0292	4.069e-25	119.0	COG1538@1|root,COG1538@2|Bacteria,1RDVP@1224|Proteobacteria,1S9NY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_3413016_2	493475.GARC_1532	1.115e-41	171.0	COG1705@1|root,COG1705@2|Bacteria	2|Bacteria	NU	amidase activity	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Amidase_2,Amidase_3,CHAP,Glucosaminidase,NLPC_P60,PG_binding_1,Rod-binding,SH3_5
GDHHQS2_k127_3413016_4	319003.Bra1253DRAFT_02360	5.855e-08	57.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,3K6K3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	gci	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_3416439_0	1340493.JNIF01000003_gene2085	0.0	1120.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3416439_2	1172186.KB911466_gene1603	3.979e-05	53.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,2358R@1762|Mycobacteriaceae	201174|Actinobacteria	P	reversible hydration of carbon dioxide	mtcA1	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS2_k127_3416439_1	234267.Acid_0024	3.191e-141	474.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_3421725_3	639030.JHVA01000001_gene3705	2.773e-67	235.0	COG2407@1|root,COG2407@2|Bacteria,3Y9FR@57723|Acidobacteria,2JP7Z@204432|Acidobacteriia	204432|Acidobacteriia	G	L-arabinose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome
GDHHQS2_k127_3421725_1	700598.Niako_3510	7.436e-188	626.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
GDHHQS2_k127_3421725_2	639030.JHVA01000001_gene3050	4.77e-86	303.0	COG1879@1|root,COG1879@2|Bacteria,3Y3RJ@57723|Acidobacteria,2JK89@204432|Acidobacteriia	2|Bacteria	K	IclR helix-turn-helix domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	HTH_IclR,LacI,Peripla_BP_4
GDHHQS2_k127_3421725_0	1340493.JNIF01000004_gene88	2.101e-267	862.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_3421777_2	234267.Acid_0669	8.185e-12	66.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_3421777_1	234267.Acid_0525	2.513e-39	157.0	COG4798@1|root,COG4798@2|Bacteria	2|Bacteria	E	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FAD_binding_4,Methyltransf_11,Methyltransf_25,Methyltransf_31,SAM_MT
GDHHQS2_k127_3421777_0	234267.Acid_3104	5.51e-270	871.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3422245_5	1267535.KB906767_gene871	2.734e-150	479.0	COG1398@1|root,COG1398@2|Bacteria,3Y6GE@57723|Acidobacteria	57723|Acidobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS2_k127_3422245_6	1267535.KB906767_gene897	8.807e-133	428.0	COG5002@1|root,COG5002@2|Bacteria,3Y99C@57723|Acidobacteria,2JP5N@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_3422245_7	234267.Acid_2403	3.198e-115	377.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria	57723|Acidobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3422245_2	1485544.JQKP01000003_gene282	1.106e-178	569.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,2WFEH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
GDHHQS2_k127_3422245_16	373994.Riv7116_0215	6.994e-09	66.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1HN52@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS2_k127_3422245_14	1123276.KB893268_gene4897	3.378e-14	76.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
GDHHQS2_k127_3422245_12	65093.PCC7418_1173	3.226e-20	95.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_3422245_11	118163.Ple7327_4640	6.536e-24	110.0	COG4634@1|root,COG4634@2|Bacteria,1G7AE@1117|Cyanobacteria,3VKR3@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3422245_3	1267533.KB906733_gene3215	6.629e-159	534.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_3422245_9	1267534.KB906759_gene1808	3.37e-32	129.0	COG0454@1|root,COG0456@2|Bacteria,3Y71G@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_3422245_10	1395571.TMS3_0114740	9.597e-26	111.0	COG0454@1|root,COG0456@2|Bacteria,1R8G2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
GDHHQS2_k127_3422245_13	448385.sce7110	1.271e-14	73.0	COG0454@1|root,COG0456@2|Bacteria,1PWDA@1224|Proteobacteria,43586@68525|delta/epsilon subdivisions,2WZJ8@28221|Deltaproteobacteria,2Z296@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_3422245_0	234267.Acid_4489	2.438e-260	825.0	COG0577@1|root,COG0577@2|Bacteria,3Y34I@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3422245_1	234267.Acid_4431	6.596e-225	734.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_3422245_8	502025.Hoch_1576	2.867e-50	197.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_3422245_17	234267.Acid_4036	5.652e-05	55.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
GDHHQS2_k127_3422245_15	234267.Acid_6867	2.863e-09	58.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
GDHHQS2_k127_3422245_4	1267535.KB906767_gene628	6.625e-154	492.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria,2JHXU@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS2_k127_3437789_1	1323361.JPOC01000017_gene2070	1.352e-34	141.0	COG3858@1|root,COG3858@2|Bacteria,2HZ7I@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
GDHHQS2_k127_3437789_0	204669.Acid345_4431	4.141e-39	164.0	COG0265@1|root,COG0265@2|Bacteria,3Y99F@57723|Acidobacteria,2JJ0S@204432|Acidobacteriia	204432|Acidobacteriia	O	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
GDHHQS2_k127_3437789_2	234267.Acid_1312	6.412e-12	74.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3445268_1	1340493.JNIF01000004_gene206	3.143e-110	373.0	COG4963@1|root,COG4963@2|Bacteria,3Y44H@57723|Acidobacteria	2|Bacteria	U	AAA domain	cpaE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ
GDHHQS2_k127_3445268_2	1267535.KB906767_gene959	4.684e-65	229.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS2_k127_3445268_0	234267.Acid_5819	2.971e-211	671.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
GDHHQS2_k127_3445268_3	1340493.JNIF01000004_gene209	1.746e-52	194.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS2_k127_3454700_0	234267.Acid_1930	2.364e-93	326.0	COG1629@1|root,COG1629@2|Bacteria,3Y3G2@57723|Acidobacteria	57723|Acidobacteria	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3468661_4	234267.Acid_4413	2.578e-75	258.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GDHHQS2_k127_3468661_1	234267.Acid_0372	2.192e-170	551.0	COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria	57723|Acidobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GDHHQS2_k127_3468661_2	1267535.KB906767_gene2246	1.299e-149	482.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria,2JIWQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS2_k127_3468661_5	234267.Acid_4416	3.748e-66	246.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
GDHHQS2_k127_3468661_3	234267.Acid_4084	1.22e-109	364.0	COG2421@1|root,COG2421@2|Bacteria,3Y40F@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GDHHQS2_k127_3468661_6	1331060.RLDS_09545	6.72e-21	94.0	COG5573@1|root,COG5573@2|Bacteria,1RKHC@1224|Proteobacteria,2UHIW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	nucleic-acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_3468661_0	1382359.JIAL01000001_gene1908	3.478e-280	882.0	COG1506@1|root,COG1506@2|Bacteria,3Y3EW@57723|Acidobacteria,2JNZU@204432|Acidobacteriia	204432|Acidobacteriia	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_3469608_2	1267534.KB906757_gene1024	0.0001944	45.0	2EKUV@1|root,33EIF@2|Bacteria,3Y5VB@57723|Acidobacteria,2JK46@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3469608_0	1267535.KB906767_gene1001	5.171e-309	969.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS2_k127_3469608_1	639030.JHVA01000001_gene603	3.795e-217	693.0	COG1629@1|root,COG1629@2|Bacteria,3Y2JN@57723|Acidobacteria,2JI08@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_347853_2	1298867.AUES01000042_gene3571	7.295e-26	114.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2U1G9@28211|Alphaproteobacteria,3K325@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_347853_3	1150600.ADIARSV_3891	2.506e-14	79.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1IRFR@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
GDHHQS2_k127_347853_0	1267535.KB906767_gene801	4.872e-180	572.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria,2JISH@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_347853_1	1123242.JH636434_gene4801	1.944e-106	350.0	COG1028@1|root,COG1028@2|Bacteria	1123242.JH636434_gene4801|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3483588_2	344747.PM8797T_04240	2.58e-49	183.0	COG2015@1|root,COG2015@2|Bacteria,2IZQC@203682|Planctomycetes	203682|Planctomycetes	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Alkyl_sulf_dimr,Lactamase_B
GDHHQS2_k127_3483588_1	639030.JHVA01000001_gene1900	8.367e-97	325.0	COG0662@1|root,COG1917@1|root,COG0662@2|Bacteria,COG1917@2|Bacteria,3Y76C@57723|Acidobacteria,2JM5A@204432|Acidobacteriia	204432|Acidobacteriia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_3483588_0	234267.Acid_7706	3.144e-124	413.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_7706|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3491845_2	452637.Oter_1891	7.695e-15	81.0	COG3250@1|root,COG3250@2|Bacteria,46UEM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Beta-galactosidase jelly roll domain	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5
GDHHQS2_k127_3491845_0	1267533.KB906739_gene2502	2.829e-57	222.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_3491845_3	632292.Calhy_2420	2.637e-13	77.0	COG2337@1|root,COG2337@2|Bacteria,1VBCG@1239|Firmicutes,24MU4@186801|Clostridia,42III@68295|Thermoanaerobacterales	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_3491845_1	1267533.KB906739_gene2502	6.591e-51	198.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_3500372_1	234267.Acid_0237	1.429e-82	280.0	COG3519@1|root,COG3519@2|Bacteria,3Y34T@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
GDHHQS2_k127_3500372_2	1267535.KB906767_gene2496	2.335e-32	131.0	COG3518@1|root,COG3518@2|Bacteria,3Y5IK@57723|Acidobacteria,2JNH9@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Type VI secretion system, lysozyme-related	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
GDHHQS2_k127_3500372_0	234267.Acid_0235	4.193e-124	418.0	COG3515@1|root,COG3515@2|Bacteria,3Y2NF@57723|Acidobacteria	57723|Acidobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
GDHHQS2_k127_3504989_0	234267.Acid_6265	2.919e-96	337.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_3515817_3	861299.J421_6345	6.08e-10	61.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_6345|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3515817_2	234267.Acid_2813	4.375e-18	91.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3515817_0	1340493.JNIF01000003_gene4673	0.0	1017.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,3Y6KG@57723|Acidobacteria	57723|Acidobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
GDHHQS2_k127_3515817_1	760192.Halhy_2296	1.76e-75	260.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS2_k127_3516333_3	314230.DSM3645_07321	1.473e-15	85.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_3516333_2	502025.Hoch_3317	4.88e-92	329.0	COG5297@1|root,COG5297@2|Bacteria,1PG5N@1224|Proteobacteria,439EZ@68525|delta/epsilon subdivisions,2X4Q8@28221|Deltaproteobacteria,2YZDX@29|Myxococcales	28221|Deltaproteobacteria	G	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_3516333_0	1267535.KB906767_gene824	1.656e-222	698.0	COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia	204432|Acidobacteriia	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_3516333_1	234267.Acid_4281	5.735e-155	498.0	COG1804@1|root,COG1804@2|Bacteria,3Y4ZM@57723|Acidobacteria	57723|Acidobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS2_k127_3520922_1	886293.Sinac_1153	2.767e-77	268.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
GDHHQS2_k127_3520922_2	483219.LILAB_32190	4.499e-24	104.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
GDHHQS2_k127_3520922_4	1346791.M529_13215	7.783e-06	52.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,2TQUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_3520922_0	1340493.JNIF01000003_gene4520	3.467e-98	332.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_3520922_3	1340493.JNIF01000003_gene4520	7.6e-11	69.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_3522693_2	1082931.KKY_1254	7.95e-111	374.0	COG3119@1|root,COG3119@2|Bacteria,1NTUU@1224|Proteobacteria,2UQWA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_3522693_0	234267.Acid_4982	1.917e-201	639.0	COG0318@1|root,COG0318@2|Bacteria,3Y68M@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_3522693_3	234267.Acid_5817	2.547e-44	167.0	COG1514@1|root,COG1514@2|Bacteria,3Y5Y2@57723|Acidobacteria	57723|Acidobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
GDHHQS2_k127_3522693_1	234267.Acid_6497	2.388e-199	648.0	COG1519@1|root,COG1663@1|root,COG1519@2|Bacteria,COG1663@2|Bacteria,3Y3X5@57723|Acidobacteria	57723|Acidobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N,LpxK
GDHHQS2_k127_3532814_3	555500.I215_00425	1.475e-17	84.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS2_k127_3532814_2	1340493.JNIF01000004_gene409	3.036e-73	255.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_3532814_4	795955.AFRW01000133_gene914	2.79e-12	70.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,1W8FR@1268|Micrococcaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	ctpA1	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_3532814_0	234267.Acid_3716	5.045e-158	507.0	COG0520@1|root,COG0520@2|Bacteria,3Y632@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_3532814_1	234267.Acid_3254	1.257e-152	490.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_3557242_5	1340493.JNIF01000003_gene2927	2.403e-08	55.0	COG0236@1|root,COG0236@2|Bacteria,3Y8JV@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS2_k127_3557242_0	234267.Acid_0743	2.17e-168	537.0	COG0304@1|root,COG0304@2|Bacteria,3Y2NT@57723|Acidobacteria	57723|Acidobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_3557242_2	671143.DAMO_0629	7.414e-26	107.0	COG1598@1|root,COG1598@2|Bacteria,2NRHH@2323|unclassified Bacteria	2|Bacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_3557242_4	1469607.KK073768_gene757	1.052e-22	101.0	COG2442@1|root,COG2442@2|Bacteria,1G8S8@1117|Cyanobacteria,1HQ3Q@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_3557242_3	118161.KB235922_gene1514	3.781e-24	106.0	COG4634@1|root,COG4634@2|Bacteria,1G86B@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3557242_1	1340493.JNIF01000003_gene4197	9.323e-123	398.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3573622_0	1453498.LG45_12680	3.485e-20	105.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_357442_6	1123248.KB893342_gene847	6.811e-119	395.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_357442_1	1267535.KB906767_gene753	4.159e-198	621.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS2_k127_357442_0	234267.Acid_5863	6.24e-272	867.0	COG4386@1|root,COG4386@2|Bacteria,3Y76B@57723|Acidobacteria	57723|Acidobacteria	S	tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_357442_10	234267.Acid_1560	1.27e-47	182.0	COG0526@1|root,COG0526@2|Bacteria,3Y64J@57723|Acidobacteria	57723|Acidobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_357442_7	1340493.JNIF01000003_gene1465	2.411e-102	342.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_357442_8	234267.Acid_1760	6.146e-75	256.0	COG0566@1|root,COG0566@2|Bacteria,3Y4WG@57723|Acidobacteria	57723|Acidobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
GDHHQS2_k127_357442_3	1123276.KB893264_gene4598	1.898e-129	462.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_357442_11	234267.Acid_3219	2.375e-25	125.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_357442_5	1123261.AXDW01000020_gene1714	4.47e-123	404.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,1X5E0@135614|Xanthomonadales	135614|Xanthomonadales	FL	Methyltransferase	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GDHHQS2_k127_357442_2	1340493.JNIF01000003_gene4404	2.111e-153	496.0	COG0845@1|root,COG0845@2|Bacteria,3Y2FV@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
GDHHQS2_k127_357442_4	1267535.KB906767_gene632	2.931e-129	415.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_357442_9	234267.Acid_3798	1.32e-60	219.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3581958_0	886293.Sinac_7090	3.139e-154	515.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3581958_1	1267535.KB906767_gene1287	1.077e-143	476.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_3581958_2	880070.Cycma_3547	0.0004509	46.0	COG1413@1|root,COG2010@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,4NGAU@976|Bacteroidetes,47NUR@768503|Cytophagia	976|Bacteroidetes	C	SPTR Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS2_k127_359380_4	234267.Acid_6610	8.59e-58	206.0	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_359380_2	1340493.JNIF01000003_gene1392	8.6e-70	250.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000003_gene1392|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_359380_0	1340493.JNIF01000004_gene234	2.801e-215	696.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_359380_1	1340493.JNIF01000004_gene233	8.811e-179	571.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_359380_3	344747.PM8797T_07699	6.334e-60	213.0	COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes	203682|Planctomycetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
GDHHQS2_k127_3594632_0	1340493.JNIF01000003_gene4600	7.378e-132	443.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3594929_0	1267534.KB906754_gene3511	3.915e-123	401.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria	57723|Acidobacteria	L	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
GDHHQS2_k127_3594929_1	886293.Sinac_2446	5.417e-60	212.0	COG1506@1|root,COG2936@1|root,COG1506@2|Bacteria,COG2936@2|Bacteria,2IYPJ@203682|Planctomycetes	203682|Planctomycetes	E	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_3596797_8	443144.GM21_3896	2.514e-20	96.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria,43TKG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
GDHHQS2_k127_3596797_6	1340493.JNIF01000003_gene4446	3.319e-42	172.0	COG2087@1|root,COG2087@2|Bacteria,3Y746@57723|Acidobacteria	57723|Acidobacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
GDHHQS2_k127_3596797_3	1340493.JNIF01000003_gene4444	2.341e-80	278.0	COG0609@1|root,COG0609@2|Bacteria,3Y7KJ@57723|Acidobacteria	57723|Acidobacteria	P	FecCD transport family	-	-	-	-	-	-	-	-	-	-	-	-	FecCD
GDHHQS2_k127_3596797_5	518766.Rmar_1591	1.353e-50	190.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,1FJ8J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS2_k127_3596797_4	1340493.JNIF01000003_gene4442	1.592e-65	234.0	COG0614@1|root,COG0614@2|Bacteria,3Y7Z8@57723|Acidobacteria	57723|Acidobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
GDHHQS2_k127_3596797_2	1340493.JNIF01000003_gene4439	5.083e-160	516.0	COG1492@1|root,COG1492@2|Bacteria,3Y64K@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
GDHHQS2_k127_3596797_1	234267.Acid_7841	3.288e-224	719.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3596797_7	234267.Acid_7841	1.529e-33	138.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3596797_0	1340493.JNIF01000003_gene4144	3e-323	1007.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3618979_2	234267.Acid_7665	6.814e-75	280.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_3618979_1	530564.Psta_2160	2.105e-78	290.0	COG1335@1|root,COG3391@1|root,COG3828@1|root,COG1335@2|Bacteria,COG3391@2|Bacteria,COG3828@2|Bacteria,2IX7K@203682|Planctomycetes	203682|Planctomycetes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,ThuA
GDHHQS2_k127_3618979_3	1122603.ATVI01000005_gene3585	0.0003116	44.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gatAX	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,Lipocalin_5
GDHHQS2_k127_363308_4	1340493.JNIF01000003_gene2320	8.189e-79	278.0	COG1629@1|root,COG4771@2|Bacteria	1340493.JNIF01000003_gene2320|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_363308_3	1340493.JNIF01000003_gene2320	3.544e-82	289.0	COG1629@1|root,COG4771@2|Bacteria	1340493.JNIF01000003_gene2320|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_363308_0	1037409.BJ6T_42530	1.574e-201	644.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_363308_1	234267.Acid_0673	1.678e-105	357.0	COG2271@1|root,COG2271@2|Bacteria,3Y3W5@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_363308_5	644966.Tmar_1373	1.135e-20	104.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS2_k127_363308_2	234267.Acid_2450	1.141e-90	304.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
GDHHQS2_k127_3636072_4	234267.Acid_6444	2.246e-57	211.0	2F776@1|root,33ZNH@2|Bacteria,3Y8A6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3636072_3	234267.Acid_1540	3.793e-72	252.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria	57723|Acidobacteria	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
GDHHQS2_k127_3636072_1	234267.Acid_3333	2.458e-148	478.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	OmpA,PD40,PI-PLC-X,Pectate_lyase22,TIR_2
GDHHQS2_k127_3636072_2	1502852.FG94_02765	3.059e-134	443.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476TQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_3636072_0	234267.Acid_3170	2.718e-170	541.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria	57723|Acidobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
GDHHQS2_k127_3637565_3	595460.RRSWK_04509	2.616e-80	279.0	COG0673@1|root,COG0673@2|Bacteria,2J321@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_3637565_2	234267.Acid_7662	1.469e-194	615.0	COG0160@1|root,COG0160@2|Bacteria,3Y4EV@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.55	ko:K00823,ko:K15372	ko00250,ko00410,ko00430,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00430,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R01684	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_3637565_1	1340493.JNIF01000003_gene2530	6.304e-209	664.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GDHHQS2_k127_3637565_0	1267535.KB906767_gene4275	3.458e-229	724.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,3Y3VV@57723|Acidobacteria,2JHRV@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
GDHHQS2_k127_3637565_4	882083.SacmaDRAFT_4422	1.96e-30	139.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DYBG@85010|Pseudonocardiales	201174|Actinobacteria	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
GDHHQS2_k127_3639925_0	401053.AciPR4_0208	5.183e-139	466.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_364335_0	1267535.KB906767_gene5197	3.169e-220	697.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,3Y5EH@57723|Acidobacteria,2JJUH@204432|Acidobacteriia	204432|Acidobacteriia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,SGL
GDHHQS2_k127_364335_1	292459.STH1014	1.723e-62	234.0	COG0028@1|root,COG0028@2|Bacteria,1UYHG@1239|Firmicutes,24FP1@186801|Clostridia	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_364335_3	143224.JQMD01000002_gene305	9.16e-27	121.0	COG3409@1|root,COG3409@2|Bacteria,4NZ6Z@976|Bacteroidetes	976|Bacteroidetes	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
GDHHQS2_k127_364335_2	1267533.KB906738_gene2179	1.008e-56	205.0	COG0457@1|root,COG0457@2|Bacteria	1267533.KB906738_gene2179|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3645443_5	234267.Acid_5981	3.648e-44	169.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3645443_1	234267.Acid_5982	1.575e-148	481.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3645443_0	1340493.JNIF01000004_gene391	1.825e-172	552.0	COG3875@1|root,COG3875@2|Bacteria,3Y6SH@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
GDHHQS2_k127_3645443_3	1123508.JH636448_gene7625	7.374e-74	259.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_3645443_2	1219035.NT2_01_05550	3.751e-77	271.0	28J0M@1|root,2Z8XS@2|Bacteria,1RKDT@1224|Proteobacteria,2U9QW@28211|Alphaproteobacteria,2KA4X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3645443_6	1267535.KB906767_gene4255	6.143e-07	52.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GDHHQS2_k127_3645443_4	234267.Acid_4469	1.364e-54	216.0	COG2227@1|root,COG2227@2|Bacteria,3Y2SJ@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3652992_3	1121033.AUCF01000010_gene4472	2.585e-20	92.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,2JPBH@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
GDHHQS2_k127_3652992_0	1207063.P24_05124	4.035e-179	566.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,2JPWU@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS2_k127_3652992_1	1207063.P24_05119	2.68e-91	302.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,2JPHK@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS2_k127_3652992_2	570952.ATVH01000015_gene1559	1.268e-78	271.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,2JRQI@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS2_k127_3653171_1	234267.Acid_7589	2.302e-65	239.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_7589|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3653171_0	234267.Acid_1306	4.03e-114	386.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3653553_5	234267.Acid_5280	4.414e-71	252.0	COG3429@1|root,COG3429@2|Bacteria,3Y7S9@57723|Acidobacteria	57723|Acidobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
GDHHQS2_k127_3653553_3	234267.Acid_5279	1.069e-83	284.0	COG0363@1|root,COG0363@2|Bacteria,3Y430@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS2_k127_3653553_4	1267535.KB906767_gene3028	2.014e-78	274.0	COG2843@1|root,COG2843@2|Bacteria,3Y8HU@57723|Acidobacteria	57723|Acidobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
GDHHQS2_k127_3653553_0	234267.Acid_5423	6.004e-270	837.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,3Y4NM@57723|Acidobacteria	57723|Acidobacteria	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
GDHHQS2_k127_3653553_6	1267535.KB906767_gene3214	8.858e-27	126.0	COG2911@1|root,COG2911@2|Bacteria,3Y8JR@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3653553_7	443143.GM18_0948	2.039e-05	57.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_35,CBM_6,GHL10,Lipase_GDSL_2
GDHHQS2_k127_3653553_2	1267535.KB906767_gene1134	3.062e-218	683.0	COG2873@1|root,COG2873@2|Bacteria,3Y2JU@57723|Acidobacteria,2JMB4@204432|Acidobacteriia	204432|Acidobacteriia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_3653553_1	1340493.JNIF01000003_gene1861	1.076e-265	837.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_3656565_1	68223.JNZY01000003_gene4821	1.825e-33	149.0	COG5184@1|root,COG5184@2|Bacteria,2I4XG@201174|Actinobacteria	201174|Actinobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3656565_0	1340493.JNIF01000004_gene402	1.005e-92	306.0	COG0693@1|root,COG0693@2|Bacteria,3Y3JB@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS2_k127_3678018_3	1267535.KB906767_gene3571	3.675e-136	464.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3678018_2	1449976.KALB_3549	1.689e-178	568.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4DXR1@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_3678018_1	234267.Acid_0475	2.263e-185	584.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_3678018_4	234267.Acid_7823	6.425e-59	219.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3678018_0	1340493.JNIF01000004_gene718	1.626e-219	701.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS2_k127_3678018_6	1235792.C808_05310	0.0001764	46.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia,27TKP@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS2_k127_3678018_5	1089547.KB913013_gene114	1.087e-10	72.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS2_k127_3682377_1	1382359.JIAL01000001_gene2036	6.313e-13	75.0	COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria,3Y3Z6@57723|Acidobacteria,2JIQG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3682377_0	1340493.JNIF01000003_gene3561	1.609e-315	994.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3682377_2	682795.AciX8_3546	9.374e-05	51.0	COG1075@1|root,COG1075@2|Bacteria,3Y8K4@57723|Acidobacteria	57723|Acidobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3685869_1	425104.Ssed_3262	5.617e-06	53.0	COG2010@1|root,COG2010@2|Bacteria,1QZNA@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
GDHHQS2_k127_3685869_0	234267.Acid_2295	2.251e-97	333.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_3685869_3	1267535.KB906767_gene1680	0.0002876	48.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_3685869_2	1340493.JNIF01000003_gene4293	3.55e-05	51.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3687169_2	1541960.KQ78_02283	1.481e-09	60.0	2E9JM@1|root,333SG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3687169_0	234267.Acid_4565	2.345e-293	915.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3687169_1	234267.Acid_4564	4.824e-279	884.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3697175_2	234267.Acid_3798	6.811e-28	119.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_3798|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3697175_1	1267535.KB906767_gene630	1.553e-115	374.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria,2JHYU@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_3697175_0	251221.35211765	1.418e-170	565.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3701492_1	266265.Bxe_C0259	8.356e-32	127.0	COG1335@1|root,COG1335@2|Bacteria,1R8Q8@1224|Proteobacteria,2VITC@28216|Betaproteobacteria,1K32V@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS2_k127_3701492_2	266264.Rmet_5214	1.135e-19	94.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_3701492_0	627192.SLG_19010	1.755e-48	182.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria	1224|Proteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_3706958_3	1267533.KB906733_gene3447	1.033e-78	282.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS2_k127_3706958_6	7897.ENSLACP00000016069	4.024e-13	69.0	COG0229@1|root,KOG0856@2759|Eukaryota,3A0GN@33154|Opisthokonta,3BPK7@33208|Metazoa,3D6BQ@33213|Bilateria,48EB7@7711|Chordata,498NZ@7742|Vertebrata	33208|Metazoa	O	L-methionine-(R)-S-oxide reductase activity	MSRB2	GO:0003674,GO:0003779,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0008152,GO:0008154,GO:0008270,GO:0009987,GO:0016043,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0022607,GO:0030029,GO:0030036,GO:0030041,GO:0030091,GO:0033743,GO:0034622,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051258,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097435,GO:1901564	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GDHHQS2_k127_3706958_2	234267.Acid_5062	2.364e-114	379.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_3706958_4	1267535.KB906767_gene1892	4.68e-71	246.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS2_k127_3706958_1	1340493.JNIF01000003_gene3551	3.948e-161	513.0	COG0752@1|root,COG0752@2|Bacteria,3Y3QC@57723|Acidobacteria	57723|Acidobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
GDHHQS2_k127_3706958_0	1340493.JNIF01000003_gene3552	9.107e-220	702.0	COG0751@1|root,COG0751@2|Bacteria,3Y3KN@57723|Acidobacteria	57723|Acidobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
GDHHQS2_k127_3706958_5	1267535.KB906767_gene1889	1.403e-30	122.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria,2JMA3@204432|Acidobacteriia	204432|Acidobacteriia	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS2_k127_3708586_0	234267.Acid_6854	5.735e-81	282.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3708586_2	1532558.JL39_29900	1.082e-27	116.0	COG1672@1|root,COG1672@2|Bacteria,1Q77U@1224|Proteobacteria,2UT6J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3708586_4	1267534.KB906756_gene430	0.0006945	49.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3708586_1	1267535.KB906767_gene1536	1.67e-72	253.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3708586_3	1276920.ADIAG_00663	5.344e-21	102.0	28MEP@1|root,2ZASB@2|Bacteria,2HAW8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3713317_0	1449080.JQMV01000003_gene322	1.303e-69	248.0	COG2244@1|root,COG2244@2|Bacteria,1WIZQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
GDHHQS2_k127_3713317_1	1173027.Mic7113_5753	7.115e-46	175.0	COG4122@1|root,COG4122@2|Bacteria,1G8BJ@1117|Cyanobacteria	1117|Cyanobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GDHHQS2_k127_3713317_2	999419.HMPREF1077_01080	1.194e-42	167.0	COG1216@1|root,COG1216@2|Bacteria,4NHY1@976|Bacteroidetes,2FNJB@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GDHHQS2_k127_3713317_3	471852.Tcur_0550	0.0002798	45.0	COG2227@1|root,COG2227@2|Bacteria,2I3C3@201174|Actinobacteria,4ER5A@85012|Streptosporangiales	201174|Actinobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_3721068_6	1267535.KB906767_gene4120	6.405e-55	202.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JP0E@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3721068_3	1267535.KB906767_gene1832	7.974e-97	331.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	-	-	-	-	-	-	-	-	-	IMS
GDHHQS2_k127_3721068_0	504472.Slin_5713	0.0	1166.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	GRASP55_65,PD40,PDZ_2,Peptidase_S41,Tricorn_C1
GDHHQS2_k127_3721068_2	497964.CfE428DRAFT_3781	9.493e-109	358.0	COG1028@1|root,COG1028@2|Bacteria	497964.CfE428DRAFT_3781|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3721068_1	1267535.KB906767_gene4476	4.957e-110	365.0	COG1082@1|root,COG1082@2|Bacteria,3Y69B@57723|Acidobacteria,2JM08@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_3721068_4	1209072.ALBT01000032_gene2077	7.487e-86	289.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,1S4WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3721068_7	714943.Mucpa_0809	3.34e-43	164.0	2E474@1|root,32Z30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3721068_8	1173024.KI912148_gene3734	1.198e-25	109.0	COG4453@1|root,COG4453@2|Bacteria,1G938@1117|Cyanobacteria,1JM6I@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
GDHHQS2_k127_3721068_5	644282.Deba_2599	5.845e-56	199.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,43BMR@68525|delta/epsilon subdivisions,2X6ZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3721068_9	1316936.K678_13483	1.542e-13	72.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,2JS16@204441|Rhodospirillales	204441|Rhodospirillales	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
GDHHQS2_k127_3732653_2	1068980.ARVW01000001_gene5702	1.745e-22	105.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4E1HT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_3732653_3	35754.JNYJ01000032_gene1767	4.234e-21	99.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DBJX@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_3732653_0	1340493.JNIF01000003_gene4631	5.349e-75	259.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_3732653_1	1096546.WYO_0582	1.734e-31	124.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,1JTB1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
GDHHQS2_k127_3740708_5	234621.RER_14970	1.448e-17	94.0	COG0671@1|root,COG0671@2|Bacteria,2H9PJ@201174|Actinobacteria,4FUP6@85025|Nocardiaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS2_k127_3740708_4	1267533.KB906742_gene676	1.049e-18	100.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria,2JM2J@204432|Acidobacteriia	204432|Acidobacteriia	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
GDHHQS2_k127_3740708_1	477641.MODMU_1794	1.923e-119	403.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
GDHHQS2_k127_3740708_2	234267.Acid_0231	5.273e-74	254.0	COG3516@1|root,COG3516@2|Bacteria,3Y4M4@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised conserved protein UCP028301	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
GDHHQS2_k127_3740708_0	234267.Acid_0232	2.13e-247	771.0	COG3517@1|root,COG3517@2|Bacteria,3Y2RM@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
GDHHQS2_k127_3740708_3	231434.JQJH01000013_gene2937	8.111e-23	100.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2U1NF@28211|Alphaproteobacteria,3NBIR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
GDHHQS2_k127_374320_0	1340493.JNIF01000003_gene3989	3.03e-06	57.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
GDHHQS2_k127_3749651_2	234267.Acid_2734	1.532e-100	345.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_3749651_3	935837.JAEK01000016_gene1301	4.814e-34	143.0	COG1957@1|root,COG1957@2|Bacteria,1U70Y@1239|Firmicutes,4IQS0@91061|Bacilli	91061|Bacilli	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
GDHHQS2_k127_3749651_1	1267535.KB906767_gene3524	3.176e-282	903.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3749651_0	234267.Acid_2177	2.836e-283	908.0	COG4932@1|root,COG4932@2|Bacteria,3Y3KQ@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3754390_2	234267.Acid_6577	4.143e-52	213.0	COG1470@1|root,COG3210@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,He_PIG,PATR,SLH
GDHHQS2_k127_3754390_3	543913.D521_0277	5.034e-05	57.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KPX9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_3754390_0	1267535.KB906767_gene5165	5.464e-112	370.0	COG3618@1|root,COG3618@2|Bacteria,3Y4BB@57723|Acidobacteria,2JJ54@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
GDHHQS2_k127_3754390_1	525373.HMPREF0766_13569	7.24e-61	216.0	COG0500@1|root,COG2226@2|Bacteria,4NFXT@976|Bacteroidetes,1IQ8H@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
GDHHQS2_k127_3756600_1	258533.BN977_04341	1.35e-62	220.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,23999@1762|Mycobacteriaceae	201174|Actinobacteria	K	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
GDHHQS2_k127_3756600_0	443598.AUFA01000003_gene2048	1.956e-73	254.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,3JYD3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS2_k127_3756600_2	234267.Acid_6108	2.331e-28	118.0	COG4798@1|root,COG4798@2|Bacteria	2|Bacteria	E	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FAD_binding_4,Methyltransf_11,Methyltransf_25,Methyltransf_31,SAM_MT
GDHHQS2_k127_3758445_1	748247.AZKH_p0406	2.911e-26	108.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2VVGN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS2_k127_3758445_0	331869.BAL199_29922	3.224e-66	231.0	COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3759058_3	234267.Acid_5915	1.938e-112	366.0	COG0003@1|root,COG0071@1|root,COG0003@2|Bacteria,COG0071@2|Bacteria,3Y60Y@57723|Acidobacteria	57723|Acidobacteria	OP	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GDHHQS2_k127_3759058_0	1267535.KB906767_gene4313	5.975e-227	709.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria,2JIFS@204432|Acidobacteriia	204432|Acidobacteriia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS2_k127_3759058_5	1267535.KB906767_gene4314	2.498e-47	174.0	COG0511@1|root,COG0511@2|Bacteria,3Y4W8@57723|Acidobacteria,2JJHQ@204432|Acidobacteriia	204432|Acidobacteriia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS2_k127_3759058_2	234267.Acid_7433	8.479e-115	380.0	COG0006@1|root,COG0006@2|Bacteria,3Y3IN@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_3759058_1	234267.Acid_5043	6.304e-167	541.0	COG0026@1|root,COG0026@2|Bacteria,3Y3RI@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
GDHHQS2_k127_3759058_4	234267.Acid_5042	5.435e-71	243.0	COG0041@1|root,COG0041@2|Bacteria,3Y4MB@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS2_k127_3759058_6	521098.Aaci_1557	1.146e-33	132.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4ISFB@91061|Bacilli	91061|Bacilli	CE	Isocitrate dehydrogenase	icd	-	1.1.1.41,1.1.1.42,1.1.1.85	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00709,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_3760510_1	1340493.JNIF01000003_gene2021	9.023e-132	452.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3760510_4	525897.Dbac_1693	6.216e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1NJFX@1224|Proteobacteria,42ZX8@68525|delta/epsilon subdivisions,2WVHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3760510_2	243090.RB7879	1.146e-107	372.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_3760510_0	1392498.JQLH01000001_gene2549	5.707e-227	722.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2PGPF@252356|Maribacter	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_3760510_3	234267.Acid_2705	1.603e-67	257.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_376365_1	402881.Plav_0614	3.036e-87	302.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,1JQ7T@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS2_k127_376365_0	1123023.JIAI01000002_gene5656	1.294e-108	362.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4E2EY@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS2_k127_376365_2	1254432.SCE1572_17850	1.509e-56	219.0	COG2960@1|root,COG2960@2|Bacteria,1R494@1224|Proteobacteria,43CJP@68525|delta/epsilon subdivisions,2X7U1@28221|Deltaproteobacteria,2YXZK@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_376365_3	448385.sce1500	1.962e-17	88.0	COG2010@1|root,COG2010@2|Bacteria,1QVQX@1224|Proteobacteria	1224|Proteobacteria	C	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_3766963_3	234267.Acid_5749	2.038e-142	481.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_3766963_4	234267.Acid_5899	2.682e-104	362.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS2_k127_3766963_2	234267.Acid_4221	6.691e-150	481.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS2_k127_3766963_1	234267.Acid_4222	1.358e-154	495.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,3Y2WU@57723|Acidobacteria	57723|Acidobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS2_k127_3766963_5	234267.Acid_4223	4.713e-85	293.0	COG0307@1|root,COG0307@2|Bacteria,3Y4EE@57723|Acidobacteria	57723|Acidobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS2_k127_3766963_6	682795.AciX8_2083	1.181e-06	53.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_3766963_0	1210884.HG799468_gene13560	4.163e-216	693.0	COG2010@1|root,COG2010@2|Bacteria,2IYFF@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_3777376_0	234267.Acid_7851	1.958e-32	143.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria	57723|Acidobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_377917_2	616991.JPOO01000001_gene3609	8.128e-17	86.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8X@178469|Arenibacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_377917_0	682795.AciX8_2271	9.16e-126	425.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_377917_1	682795.AciX8_2271	2.536e-93	321.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3785239_0	234267.Acid_5857	6.753e-300	931.0	COG0243@1|root,COG0243@2|Bacteria,3Y2IU@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS2_k127_3785239_1	1340493.JNIF01000004_gene270	1.955e-38	146.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_3796165_2	1379270.AUXF01000004_gene2894	9.779e-91	311.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_3796165_0	234267.Acid_5708	1.884e-264	818.0	COG4102@1|root,COG4102@2|Bacteria,3Y793@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3796165_1	234267.Acid_5550	3.329e-110	365.0	COG4223@1|root,COG4223@2|Bacteria,3Y6G5@57723|Acidobacteria	57723|Acidobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3800797_2	118173.KB235914_gene3652	1.193e-16	83.0	2DGVE@1|root,32U82@2|Bacteria,1G87Z@1117|Cyanobacteria,1HDAU@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3800797_0	497964.CfE428DRAFT_4511	7.043e-199	655.0	COG3119@1|root,COG3119@2|Bacteria,46UNA@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_3800797_1	1267535.KB906767_gene2038	9.026e-117	412.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
GDHHQS2_k127_3802874_3	631454.N177_4194	1.206e-40	154.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,1JPM2@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	livH	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3802874_2	402881.Plav_0172	4.944e-41	158.0	COG1695@1|root,COG1695@2|Bacteria,1N33P@1224|Proteobacteria,2VER5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GDHHQS2_k127_3802874_0	663610.JQKO01000008_gene76	9.654e-93	317.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,3NASE@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS2_k127_3802874_1	395964.KE386496_gene126	1.511e-58	208.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3NAJ7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	MA20_16805	-	-	ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
GDHHQS2_k127_3803655_3	234267.Acid_5710	3.692e-109	359.0	COG2319@1|root,COG2319@2|Bacteria,3Y5JS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GDHHQS2_k127_3803655_0	234267.Acid_5711	3.163e-269	849.0	COG2319@1|root,COG2319@2|Bacteria,3Y69Q@57723|Acidobacteria	57723|Acidobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3803655_5	1230476.C207_00029	6.174e-28	118.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria,3JWH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_3803655_2	234267.Acid_0457	3.292e-127	420.0	COG0348@1|root,COG0348@2|Bacteria,3Y3H4@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
GDHHQS2_k127_3803655_1	234267.Acid_7336	7.594e-264	822.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS2_k127_3820141_2	1046724.KB889914_gene29	1.511e-05	54.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
GDHHQS2_k127_3820141_3	240015.ACP_2717	3.529e-05	49.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3820141_0	1340493.JNIF01000003_gene3901	1.84e-137	444.0	COG0111@1|root,COG0111@2|Bacteria,3Y3VD@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_3837384_1	1340493.JNIF01000004_gene420	1.072e-93	314.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Peptidase_M9,zf-ribbon_3
GDHHQS2_k127_3837384_0	1123248.KB893325_gene1154	2.382e-175	568.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_3837384_2	1340493.JNIF01000004_gene436	6.783e-36	141.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	psbV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02720	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	iJN678.psbV	Cytochrom_C,Cytochrom_C550,Cytochrom_CIII,Cytochrome_C7
GDHHQS2_k127_3842415_0	234267.Acid_7263	0.0	1374.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS2_k127_3842415_4	234267.Acid_7262	4.268e-140	452.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3842415_5	234267.Acid_7261	3.615e-62	224.0	COG1266@1|root,COG1266@2|Bacteria,3Y54S@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_3842415_2	234267.Acid_1486	4.511e-166	527.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GDHHQS2_k127_3842415_6	1120950.KB892810_gene7216	1.529e-46	186.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_3842415_8	1288494.EBAPG3_8410	4.986e-07	51.0	COG4644@1|root,COG4644@2|Bacteria	2|Bacteria	-	-	tnpA	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
GDHHQS2_k127_3842415_7	90813.JQMT01000001_gene1566	3.039e-20	93.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S08N@1236|Gammaproteobacteria,4611V@72273|Thiotrichales	72273|Thiotrichales	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
GDHHQS2_k127_3842415_1	639030.JHVA01000001_gene1889	0.0	1095.0	COG1629@1|root,COG4771@2|Bacteria,3Y9D4@57723|Acidobacteria,2JP0W@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3842415_3	401053.AciPR4_2893	1.254e-140	456.0	COG3547@1|root,COG3547@2|Bacteria,3Y5SI@57723|Acidobacteria,2JKWK@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS2_k127_3847086_1	234267.Acid_4308	7.642e-62	225.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,IU_nuc_hydro
GDHHQS2_k127_3847086_0	234267.Acid_4306	9.493e-161	519.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_3847086_2	1340493.JNIF01000003_gene4273	5.921e-23	101.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_3848144_3	1121422.AUMW01000028_gene3401	1.009e-46	186.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_3848144_6	1231057.AMGD01000104_gene265	3.289e-08	55.0	2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4HZXQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3848144_1	234267.Acid_4390	4.708e-139	452.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_3848144_4	1340493.JNIF01000003_gene4328	6.398e-27	121.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
GDHHQS2_k127_3848144_2	266265.Bxe_B0040	8.474e-114	386.0	COG0738@1|root,COG0738@2|Bacteria,1R3UK@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_3848144_0	4641.GSMUA_Achr2P10430_001	2.716e-173	552.0	COG0334@1|root,KOG2250@2759|Eukaryota,37Q3I@33090|Viridiplantae,3GC9F@35493|Streptophyta,3KVGG@4447|Liliopsida	35493|Streptophyta	E	Belongs to the Glu Leu Phe Val dehydrogenases family	GDH2	GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009267,GO:0009268,GO:0009409,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010446,GO:0016020,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0030554,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0051716,GO:0055114,GO:0071496,GO:0097159,GO:0097367,GO:0098588,GO:0098805,GO:1901265,GO:1901363,GO:1901698	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS2_k127_3848144_5	1047013.AQSP01000073_gene1092	2.168e-10	68.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
GDHHQS2_k127_3856066_5	1123401.JHYQ01000023_gene1177	3.473e-11	63.0	COG4974@1|root,COG4974@2|Bacteria,1R43B@1224|Proteobacteria,1RZ03@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_3856066_1	595460.RRSWK_03115	2.968e-128	427.0	COG1520@1|root,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_3856066_3	234267.Acid_5275	3.723e-20	91.0	COG5485@1|root,COG5485@2|Bacteria,3Y7IQ@57723|Acidobacteria	57723|Acidobacteria	S	SnoaL-like polyketide cyclase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	SnoaL
GDHHQS2_k127_3856066_4	234267.Acid_5275	5.864e-13	70.0	COG5485@1|root,COG5485@2|Bacteria,3Y7IQ@57723|Acidobacteria	57723|Acidobacteria	S	SnoaL-like polyketide cyclase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	SnoaL
GDHHQS2_k127_3856066_0	1267535.KB906767_gene3391	3.091e-236	744.0	COG0488@1|root,COG0488@2|Bacteria,3Y2H0@57723|Acidobacteria,2JI7S@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS2_k127_3856066_2	1120999.JONM01000034_gene3994	1.782e-36	142.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2VJFB@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase (SDR)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS2_k127_3856622_0	234267.Acid_7648	4.745e-318	991.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
GDHHQS2_k127_3856622_1	204669.Acid345_4386	2.947e-200	644.0	COG1649@1|root,COG1649@2|Bacteria,3Y2XT@57723|Acidobacteria,2JIYN@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3856622_2	1340493.JNIF01000003_gene2517	9.515e-28	118.0	COG1629@1|root,COG4771@2|Bacteria,3Y3NM@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3858214_0	391587.KAOT1_19172	8.007e-48	190.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1HZSJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
GDHHQS2_k127_3858214_1	390989.JOEG01000005_gene2136	2.711e-39	159.0	COG0467@1|root,COG0467@2|Bacteria,2I9WA@201174|Actinobacteria,4DESD@85008|Micromonosporales	201174|Actinobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol,Toprim_3
GDHHQS2_k127_3863932_12	1122963.AUHB01000011_gene1315	9.592e-64	225.0	COG1680@1|root,COG1680@2|Bacteria,1PDR2@1224|Proteobacteria,2U487@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_3863932_1	1267535.KB906767_gene2963	2.623e-180	574.0	COG1160@1|root,COG1160@2|Bacteria,3Y3AC@57723|Acidobacteria,2JIAS@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS2_k127_3863932_9	1123242.JH636435_gene2640	8.841e-82	279.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	MA20_16785	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3863932_2	1298864.AUEQ01000008_gene2193	8.012e-154	494.0	COG1409@1|root,COG1409@2|Bacteria,2I95A@201174|Actinobacteria,2377P@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_3863932_13	886293.Sinac_3318	8.097e-47	185.0	COG2271@1|root,COG2807@1|root,COG2271@2|Bacteria,COG2807@2|Bacteria,2IZV2@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_3863932_0	391624.OIHEL45_11965	7.825e-211	672.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS2_k127_3863932_11	1380393.JHVP01000007_gene4492	4.399e-75	262.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
GDHHQS2_k127_3863932_14	234267.Acid_3219	3.607e-29	138.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3863932_3	1123278.KB893615_gene5179	1.168e-131	469.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_3863932_6	234267.Acid_2012	4.895e-94	321.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	sumf2	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_14,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_3863932_7	234267.Acid_2011	1.252e-88	297.0	COG0325@1|root,COG0325@2|Bacteria,3Y4CY@57723|Acidobacteria	57723|Acidobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS2_k127_3863932_5	234267.Acid_2703	1.616e-99	339.0	28N30@1|root,2ZB8S@2|Bacteria,3Y2XH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3863932_4	1340493.JNIF01000003_gene4835	9.41e-117	392.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	ampH	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
GDHHQS2_k127_3863932_8	504472.Slin_3334	2.341e-88	316.0	COG2367@1|root,COG2367@2|Bacteria,4NE3C@976|Bacteroidetes,47M1M@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	per1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS2_k127_3863932_10	1340493.JNIF01000003_gene3570	3.665e-80	270.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_3866711_2	1267534.KB906757_gene995	1.169e-68	244.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_3866711_4	234267.Acid_6993	2.787e-28	125.0	COG0584@1|root,COG0584@2|Bacteria,3Y41Q@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS2_k127_3866711_1	1117379.BABA_03844	2.408e-211	668.0	COG4799@1|root,COG4799@2|Bacteria,1VTDE@1239|Firmicutes,4HU50@91061|Bacilli,1ZFG8@1386|Bacillus	91061|Bacilli	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS2_k127_3866711_5	204669.Acid345_2759	5.404e-18	90.0	2E5J5@1|root,330AF@2|Bacteria,3Y5HZ@57723|Acidobacteria,2JJVY@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS2_k127_3866711_0	1210884.HG799465_gene12236	1.942e-258	819.0	COG1506@1|root,COG1506@2|Bacteria,2IYRT@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_3866711_3	234267.Acid_6875	5.92e-66	233.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3868174_1	215803.DB30_3885	2.514e-23	111.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,430V0@68525|delta/epsilon subdivisions,2WVT6@28221|Deltaproteobacteria,2YXP7@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS2_k127_3868174_0	95619.PM1_0222010	2.945e-128	417.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	dcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_3869095_2	1267535.KB906767_gene3524	4.448e-112	372.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3869095_1	234267.Acid_5052	7.897e-175	559.0	COG4948@1|root,COG4948@2|Bacteria,3Y6GX@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_3869095_4	1096546.WYO_3215	1.136e-18	88.0	COG2886@1|root,COG2886@2|Bacteria,1P8QR@1224|Proteobacteria,2V2AU@28211|Alphaproteobacteria,1JYAF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GDHHQS2_k127_3869095_3	1096546.WYO_3214	6.175e-30	123.0	COG2405@1|root,COG2405@2|Bacteria,1PVSD@1224|Proteobacteria,2V1ZP@28211|Alphaproteobacteria,1JXVD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GDHHQS2_k127_3869095_0	234267.Acid_1309	3.799e-192	601.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS2_k127_3873474_2	234267.Acid_7823	2.941e-41	154.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3873474_0	234267.Acid_7742	1.538e-82	284.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
GDHHQS2_k127_3873474_1	575540.Isop_0300	2.285e-61	220.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS2_k127_3876482_5	404589.Anae109_4434	8.864e-11	68.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,43085@68525|delta/epsilon subdivisions,2WVFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
GDHHQS2_k127_3876482_3	1463825.JNXC01000001_gene5462	2.45e-38	158.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4EEG6@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_3876482_2	485917.Phep_3908	4.92e-55	204.0	COG0463@1|root,COG0463@2|Bacteria,4NEQK@976|Bacteroidetes,1IWGE@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_3876482_0	886293.Sinac_3894	5.276e-110	365.0	COG0451@1|root,COG0451@2|Bacteria,2IYKW@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_3876482_1	106370.Francci3_1299	1.259e-65	237.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_3876482_4	304371.MCP_0143	9.151e-13	80.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,2N9R4@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_3880261_7	1267535.KB906767_gene1162	6.683e-17	83.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_3880261_3	234267.Acid_5285	1.749e-48	185.0	COG1216@1|root,COG1216@2|Bacteria,3Y5FE@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GDHHQS2_k127_3880261_2	926566.Terro_2926	1.369e-55	213.0	COG1609@1|root,COG1609@2|Bacteria,3Y352@57723|Acidobacteria,2JIA2@204432|Acidobacteriia	2|Bacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GntR,LacI,Peripla_BP_1,Peripla_BP_3
GDHHQS2_k127_3880261_1	234267.Acid_7221	1.244e-101	355.0	COG2271@1|root,COG2271@2|Bacteria,3Y2VG@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_3880261_5	671143.DAMO_0611	8.61e-34	146.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS2_k127_3880261_0	1267535.KB906767_gene2972	3.476e-244	764.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GDHHQS2_k127_3880261_6	279238.Saro_2119	4.335e-31	131.0	2DPIB@1|root,3326Z@2|Bacteria,1NHPZ@1224|Proteobacteria,2UTAH@28211|Alphaproteobacteria,2KAT0@204457|Sphingomonadales	204457|Sphingomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
GDHHQS2_k127_3885367_3	204669.Acid345_1110	7.342e-105	346.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GDHHQS2_k127_3885367_1	234267.Acid_6984	3.577e-134	437.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_3885367_0	234267.Acid_6983	1.002e-174	553.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_3885367_2	234267.Acid_6982	3.468e-129	422.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
GDHHQS2_k127_3886546_0	68223.JNZY01000003_gene4821	6.573e-32	142.0	COG5184@1|root,COG5184@2|Bacteria,2I4XG@201174|Actinobacteria	201174|Actinobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3886546_1	575615.HMPREF0670_02200	1.424e-07	58.0	2D1WT@1|root,32TBK@2|Bacteria,4NU82@976|Bacteroidetes,2FSMN@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3900944_1	1267535.KB906767_gene719	2.476e-113	367.0	COG1262@1|root,COG1262@2|Bacteria,3Y4J6@57723|Acidobacteria,2JM73@204432|Acidobacteriia	204432|Acidobacteriia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_3900944_0	234267.Acid_7606	7.574e-194	618.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3902282_0	1254432.SCE1572_33155	1.073e-43	168.0	COG0667@1|root,COG0667@2|Bacteria,1NWQE@1224|Proteobacteria,42ZW2@68525|delta/epsilon subdivisions,2WVDI@28221|Deltaproteobacteria,2YVXI@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2
GDHHQS2_k127_3902282_2	646529.Desaci_0681	3.624e-15	85.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_3902282_1	1112214.AHIS01000056_gene2938	1.427e-42	175.0	COG5512@1|root,COG5512@2|Bacteria,1R4BG@1224|Proteobacteria,2U415@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
GDHHQS2_k127_3902282_3	926566.Terro_2941	3.962e-14	78.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria,2JKDK@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3910761_0	1340493.JNIF01000003_gene1667	5.426e-94	316.0	COG0351@1|root,COG0351@2|Bacteria,3Y4DB@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
GDHHQS2_k127_3910761_1	234267.Acid_0433	4.358e-90	316.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_3910761_2	1340493.JNIF01000003_gene1669	1.25e-09	60.0	COG3345@1|root,COG3345@2|Bacteria,3Y8BZ@57723|Acidobacteria	57723|Acidobacteria	G	Melibiase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
GDHHQS2_k127_3911140_0	1144319.PMI16_00782	6.061e-143	471.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,47391@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Penicillin amidase	penA	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_394204_0	234267.Acid_0053	3.134e-137	459.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria	57723|Acidobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS2_k127_3942781_1	1173027.Mic7113_5936	5.46e-86	291.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
GDHHQS2_k127_3942781_2	234267.Acid_3374	1.509e-30	130.0	COG3288@1|root,COG3288@2|Bacteria,3Y5PH@57723|Acidobacteria	57723|Acidobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
GDHHQS2_k127_3942781_0	204669.Acid345_4185	1.31e-177	566.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria,2JM1F@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
GDHHQS2_k127_3944346_0	671143.DAMO_2345	4.095e-136	440.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	lspL	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_3946760_0	1242864.D187_003092	2.477e-53	209.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,Pkinase,WD40
GDHHQS2_k127_3946760_1	1283299.AUKG01000001_gene2424	2.896e-32	134.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
GDHHQS2_k127_3964903_4	1340493.JNIF01000003_gene3714	9.115e-33	130.0	COG3063@1|root,COG3063@2|Bacteria,3Y5SX@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
GDHHQS2_k127_3964903_2	868595.Desca_1276	4.216e-82	289.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
GDHHQS2_k127_3964903_0	357808.RoseRS_3858	1.315e-271	873.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
GDHHQS2_k127_3964903_1	1009370.ALO_18390	3.519e-111	374.0	COG1055@1|root,COG1055@2|Bacteria,1TRZC@1239|Firmicutes,4H1XG@909932|Negativicutes	909932|Negativicutes	P	Dicarboxylate carrier MatC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
GDHHQS2_k127_3964903_3	1267535.KB906767_gene2531	2.599e-56	199.0	COG1482@1|root,COG1482@2|Bacteria,3Y6FR@57723|Acidobacteria	57723|Acidobacteria	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3966708_1	1340493.JNIF01000003_gene4529	1.215e-164	549.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3966708_5	234267.Acid_1102	6.386e-82	291.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_3966708_4	234267.Acid_1101	2.382e-84	286.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3966708_3	1267535.KB906767_gene3453	4.23e-109	364.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_3966708_8	1256908.HMPREF0373_01282	4.831e-26	112.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25WVB@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_3966708_10	526227.Mesil_1481	6.444e-09	66.0	COG0702@1|root,COG0702@2|Bacteria,1WI5F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	PFAM NAD dependent epimerase dehydratase family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
GDHHQS2_k127_3966708_6	234267.Acid_4835	5.235e-81	278.0	COG1573@1|root,COG1573@2|Bacteria,3Y4AT@57723|Acidobacteria	57723|Acidobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_3966708_0	471854.Dfer_2454	5.25e-202	647.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,47JKV@768503|Cytophagia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_3966708_7	1267535.KB906767_gene4927	1.997e-80	276.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_3966708_11	1267535.KB906767_gene4927	2.141e-08	57.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_3966895_2	234267.Acid_2648	1.72e-34	135.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.6.3.38	ko:K07214,ko:K09689	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101	-	-	Esterase,SGL
GDHHQS2_k127_3966895_1	234267.Acid_4598	1.209e-100	337.0	COG0253@1|root,COG0253@2|Bacteria,3Y4EC@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS2_k127_3966895_0	1267535.KB906767_gene1723	4.54e-208	654.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria,2JIIN@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS2_k127_3966895_3	234267.Acid_1376	2.224e-19	93.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_39671_0	1131814.JAFO01000001_gene3953	1.886e-28	119.0	COG0457@1|root,COG0457@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria,3EY8Y@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_39671_1	641491.DND132_2827	3.459e-11	75.0	2AHEC@1|root,317RG@2|Bacteria,1PZ43@1224|Proteobacteria,43E9U@68525|delta/epsilon subdivisions,2X03U@28221|Deltaproteobacteria,2MABR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3969552_0	234267.Acid_2982	1.52e-137	447.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3969552_1	688246.Premu_1049	9.644e-10	66.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_3970050_0	234267.Acid_3977	0.0	1363.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_3970481_2	1229172.JQFA01000004_gene1470	1.422e-07	54.0	COG1649@1|root,COG1649@2|Bacteria,1G056@1117|Cyanobacteria,1H71J@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH
GDHHQS2_k127_3970481_1	234267.Acid_5946	7.525e-35	144.0	COG0454@1|root,COG0456@2|Bacteria,3Y8IK@57723|Acidobacteria	57723|Acidobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_3970481_0	234267.Acid_0690	0.0	1112.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS2_k127_3977570_1	377629.TERTU_2924	7.428e-46	169.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,1S295@1236|Gammaproteobacteria,2PPIZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
GDHHQS2_k127_3977570_0	1340493.JNIF01000003_gene4520	8.355e-113	377.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_3977570_2	1267535.KB906767_gene265	3.273e-13	74.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,RNase_Zc3h12a
GDHHQS2_k127_3978993_4	1340493.JNIF01000003_gene1974	1.347e-147	470.0	COG2170@1|root,COG2170@2|Bacteria,3Y6P8@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
GDHHQS2_k127_3978993_3	1340493.JNIF01000003_gene1975	2.275e-157	505.0	COG2309@1|root,COG2309@2|Bacteria,3Y46T@57723|Acidobacteria	57723|Acidobacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
GDHHQS2_k127_3978993_5	1340493.JNIF01000003_gene1976	8.434e-146	473.0	COG2308@1|root,COG2308@2|Bacteria,3Y663@57723|Acidobacteria	57723|Acidobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3978993_2	234267.Acid_6651	2.055e-206	662.0	COG0154@1|root,COG0154@2|Bacteria,3Y3E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GDHHQS2_k127_3978993_12	1403819.BATR01000105_gene3642	0.0004861	48.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_3978993_8	234267.Acid_7358	3.882e-111	367.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100,4.2.1.17	ko:K01715,ko:K07537	ko00362,ko00650,ko01100,ko01120,ko01200,ko01220,map00362,map00650,map01100,map01120,map01200,map01220	M00541	R03026,R05597	RC00831,RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_3978993_11	234267.Acid_2654	9.139e-06	55.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	ttr	-	-	ko:K19113	ko00261,ko01130,map00261,map01130	-	R10893	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_3978993_1	1210884.HG799475_gene15269	2.686e-252	789.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_3978993_9	1121943.KB899990_gene3757	7.5e-89	324.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_3978993_0	234267.Acid_0759	0.0	1044.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,Peptidase_S9
GDHHQS2_k127_3978993_6	234267.Acid_4834	1.577e-122	405.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria	57723|Acidobacteria	M	PFAM penicillin-binding protein transpeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
GDHHQS2_k127_3978993_7	1340493.JNIF01000003_gene2136	2.492e-111	367.0	COG1028@1|root,COG1028@2|Bacteria,3Y2YB@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_3978993_10	313628.LNTAR_01922	9.362e-08	55.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_3985509_0	1267535.KB906767_gene2414	1.647e-276	858.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria,2JI90@204432|Acidobacteriia	204432|Acidobacteriia	EH	Acetolactate synthase, large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_3985509_1	886293.Sinac_6924	1.058e-22	102.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_3986651_2	1340493.JNIF01000003_gene2955	9.139e-33	130.0	2FIG5@1|root,34A8B@2|Bacteria,3Y8GN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3986651_0	1123277.KB893174_gene5952	1.495e-125	421.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
GDHHQS2_k127_3986651_1	861299.J421_6226	2.595e-102	351.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3988000_1	497964.CfE428DRAFT_4557	6.793e-54	194.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3988000_0	743719.PaelaDRAFT_3973	4.568e-73	255.0	COG2207@1|root,COG2207@2|Bacteria,1VIQW@1239|Firmicutes,4IR31@91061|Bacilli,26XKY@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_3988000_2	506534.Rhein_1480	3.09e-38	150.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3989644_2	1047013.AQSP01000125_gene2637	3.565e-40	160.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
GDHHQS2_k127_3989644_3	1047013.AQSP01000091_gene656	3.113e-14	79.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TPR_6
GDHHQS2_k127_3989644_1	234267.Acid_4320	7.401e-86	289.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3989644_0	234267.Acid_4321	6.691e-105	364.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_3992828_1	234267.Acid_0264	3.96e-77	271.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
GDHHQS2_k127_3992828_0	234267.Acid_5004	7.691e-192	630.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_3992828_2	1340493.JNIF01000004_gene404	1.481e-09	60.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_3993028_1	1123073.KB899241_gene2586	1.608e-27	129.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
GDHHQS2_k127_3993028_0	1340493.JNIF01000003_gene4293	1.067e-108	383.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_3994658_0	1499967.BAYZ01000068_gene1971	4.933e-64	233.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_3994658_1	234267.Acid_5168	4.704e-31	123.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria	57723|Acidobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS2_k127_3994658_2	1386089.N865_15440	1.256e-14	75.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4FED1@85021|Intrasporangiaceae	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
GDHHQS2_k127_3998621_0	682795.AciX8_2271	6.196e-211	687.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_3998621_6	1267535.KB906767_gene3549	1.219e-35	140.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS2_k127_3998621_3	1267535.KB906767_gene3904	8.441e-77	260.0	COG0634@1|root,COG0634@2|Bacteria,3Y2FD@57723|Acidobacteria,2JJ7Z@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_3998621_1	234267.Acid_3577	2.49e-174	565.0	COG0249@1|root,COG0249@2|Bacteria,3Y48T@57723|Acidobacteria	57723|Acidobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
GDHHQS2_k127_3998621_5	485918.Cpin_6086	2.711e-39	159.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,DUF1906,HAMP,HisKA,Muraidase,PAS_8,PG_binding_1,Peptidase_M15_4
GDHHQS2_k127_3998621_2	760192.Halhy_3752	1.26e-126	419.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1IW1W@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_400087_5	1340493.JNIF01000003_gene3520	1.26e-90	301.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_400087_4	290397.Adeh_3929	2.528e-120	393.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS2_k127_400087_3	234267.Acid_1756	2.464e-121	395.0	COG1378@1|root,COG1378@2|Bacteria,3Y66F@57723|Acidobacteria	57723|Acidobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
GDHHQS2_k127_400087_1	1267535.KB906767_gene2974	2.388e-165	530.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_400087_0	234267.Acid_1492	9.18e-277	856.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_400087_2	234267.Acid_4427	5.582e-132	434.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria	57723|Acidobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS2_k127_4002314_2	1144307.PMI04_03760	6.02e-18	90.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	pla	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_bact_N
GDHHQS2_k127_4002314_1	1458275.AZ34_04145	4.027e-64	231.0	COG4122@1|root,COG4122@2|Bacteria,1MYYK@1224|Proteobacteria,2VYI5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
GDHHQS2_k127_4002314_0	234267.Acid_7684	4.841e-68	254.0	COG5640@1|root,COG5640@2|Bacteria,3Y80T@57723|Acidobacteria	57723|Acidobacteria	O	endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4008249_0	497964.CfE428DRAFT_4340	1.011e-185	593.0	COG3119@1|root,COG3119@2|Bacteria,46UNA@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_4008249_3	1267535.KB906767_gene881	5.206e-29	128.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4008249_4	329726.AM1_6367	7.958e-15	78.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS2_k127_4008249_2	1267535.KB906767_gene3691	1.075e-72	257.0	COG1082@1|root,COG1082@2|Bacteria,3Y6EB@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_4008249_1	1122180.Lokhon_02418	1.59e-74	258.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2P8IZ@245186|Loktanella	28211|Alphaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	MA20_35585	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
GDHHQS2_k127_4017231_1	530564.Psta_3533	6.582e-05	50.0	COG5492@1|root,COG5492@2|Bacteria,2IXPF@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_4017231_0	1340493.JNIF01000003_gene1755	4.95e-78	278.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4017677_4	234267.Acid_4466	7.615e-31	124.0	COG2367@1|root,COG2367@2|Bacteria,3Y3UF@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS2_k127_4017677_3	1274374.CBLK010000053_gene2351	8.041e-34	138.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4017677_2	204669.Acid345_1931	5.265e-52	188.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria,2JN23@204432|Acidobacteriia	204432|Acidobacteriia	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_4017677_0	1267533.KB906738_gene2186	2.27e-211	677.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
GDHHQS2_k127_4017677_1	204669.Acid345_0292	8.213e-76	285.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
GDHHQS2_k127_4017677_5	204669.Acid345_0293	1.609e-14	79.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	3.2.1.51	ko:K01206,ko:K07114,ko:K07126	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04147	1.A.13.2.2,1.A.13.2.3	GH29	-	FecR,SPOR,TPR_6
GDHHQS2_k127_4019038_9	234267.Acid_1227	6.461e-38	155.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1227|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4019038_2	234267.Acid_3175	4.794e-105	365.0	COG1075@1|root,COG1404@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,3Y2EZ@57723|Acidobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GDHHQS2_k127_4019038_1	1340493.JNIF01000004_gene779	8.676e-148	477.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_4019038_3	234267.Acid_5208	5.73e-103	354.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM glutamate formiminotransferase	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS2_k127_4019038_11	1183438.GKIL_4222	7.179e-16	88.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_4019038_8	2045.KR76_05385	2.873e-45	173.0	COG2201@1|root,COG2201@2|Bacteria,2GMBC@201174|Actinobacteria,4DS9F@85009|Propionibacteriales	201174|Actinobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS2_k127_4019038_13	1340493.JNIF01000003_gene2955	0.0001799	49.0	2FIG5@1|root,34A8B@2|Bacteria,3Y8GN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4019038_6	1267535.KB906767_gene2653	5.041e-75	261.0	COG2912@1|root,COG2912@2|Bacteria,3Y53Z@57723|Acidobacteria,2JMYF@204432|Acidobacteriia	204432|Acidobacteriia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
GDHHQS2_k127_4019038_4	344747.PM8797T_16665	4.564e-101	347.0	COG1520@1|root,COG1520@2|Bacteria,2J2HQ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_4019038_7	1340493.JNIF01000003_gene1829	5.186e-70	245.0	28IJE@1|root,2Z8KB@2|Bacteria,3Y46I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4019038_0	234267.Acid_1883	3.734e-207	659.0	COG2133@1|root,COG2133@2|Bacteria,3Y36R@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_4019038_5	1267535.KB906767_gene365	8.692e-97	329.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_18	140110.NechaP32791	1.652e-05	58.0	2CMGW@1|root,2QQB7@2759|Eukaryota,39TQ2@33154|Opisthokonta,3NZ5T@4751|Fungi,3QR06@4890|Ascomycota,215XR@147550|Sordariomycetes,3TEVV@5125|Hypocreales,1FN2G@110618|Nectriaceae	4751|Fungi	S	viral a-type inclusion protein repeat domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_17	1216976.AX27061_3292	1.326e-15	88.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	BON,OmpA
GDHHQS2_k127_4024953_8	886293.Sinac_3184	1.046e-73	267.0	28JEC@1|root,2Z98J@2|Bacteria,2IX0J@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_1	1340493.JNIF01000003_gene2039	5.396e-166	527.0	2E9F7@1|root,333NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_0	234267.Acid_0822	1.191e-166	541.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_4024953_13	234267.Acid_4931	2.438e-35	141.0	2FIDY@1|root,34A64@2|Bacteria,3Y8PB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_4	234267.Acid_4410	2.988e-127	411.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS2_k127_4024953_5	1340493.JNIF01000003_gene4176	2.778e-110	363.0	COG0330@1|root,COG0330@2|Bacteria,3Y7B6@57723|Acidobacteria	57723|Acidobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_4024953_16	1379270.AUXF01000001_gene2022	7.925e-16	78.0	COG4877@1|root,COG4877@2|Bacteria,1ZVAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_7	234267.Acid_0378	2.887e-80	276.0	COG0859@1|root,COG0859@2|Bacteria,3Y7R7@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GDHHQS2_k127_4024953_14	234267.Acid_5380	7.753e-35	138.0	COG4233@1|root,COG4233@2|Bacteria,3Y9AX@57723|Acidobacteria	57723|Acidobacteria	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
GDHHQS2_k127_4024953_9	1340493.JNIF01000003_gene4261	7.135e-64	224.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
GDHHQS2_k127_4024953_12	234267.Acid_5382	5.473e-36	145.0	2FC4E@1|root,3448B@2|Bacteria,3Y8HE@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4024953_10	1340493.JNIF01000003_gene4262	7.99e-57	209.0	COG0760@1|root,COG0760@2|Bacteria,3Y890@57723|Acidobacteria	57723|Acidobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
GDHHQS2_k127_4024953_3	497964.CfE428DRAFT_0230	9.396e-133	454.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,46TGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_4024953_2	1121468.AUBR01000024_gene3021	1.375e-153	504.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_4024953_6	314287.GB2207_00960	4.081e-90	311.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,1SJUT@1236|Gammaproteobacteria,1J957@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4026668_2	344747.PM8797T_21003	6.156e-25	107.0	COG3836@1|root,COG3836@2|Bacteria,2IX9H@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_4026668_1	1434325.AZQN01000004_gene1579	9.216e-31	137.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,4PN23@976|Bacteroidetes,47QCB@768503|Cytophagia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4026668_0	1123242.JH636436_gene641	7.295e-37	145.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4028644_0	1267535.KB906767_gene880	1.87e-117	394.0	COG0612@1|root,COG0612@2|Bacteria,3Y2FB@57723|Acidobacteria,2JHWY@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
GDHHQS2_k127_4028644_2	234267.Acid_6420	6.622e-68	241.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4028644_1	945713.IALB_1976	1.722e-106	374.0	COG0348@1|root,COG0492@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4_5,Fer4_9,Pyr_redox_3
GDHHQS2_k127_4028644_3	1313172.YM304_22880	6.221e-05	53.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,RCC1,RCC1_2,fn3
GDHHQS2_k127_4038566_2	1121875.KB907549_gene1707	3.944e-38	154.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
GDHHQS2_k127_4038566_0	1340493.JNIF01000003_gene1702	1.677e-197	622.0	COG0498@1|root,COG0498@2|Bacteria,3Y2GX@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_4038566_1	234267.Acid_7123	6.737e-105	348.0	COG0438@1|root,COG0438@2|Bacteria,3Y867@57723|Acidobacteria	57723|Acidobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4041633_2	1185876.BN8_03287	1.625e-160	516.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4041633_6	1128427.KB904821_gene3273	2.987e-65	229.0	COG4636@1|root,COG4636@2|Bacteria,1G0G0@1117|Cyanobacteria,1H8E7@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_4041633_9	162425.CADANIAP00009346	1.615e-10	73.0	COG1053@1|root,KOG2404@2759|Eukaryota,38G7N@33154|Opisthokonta,3NUME@4751|Fungi,3QQ0A@4890|Ascomycota,20ESM@147545|Eurotiomycetes,3S5ZU@5042|Eurotiales	4751|Fungi	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
GDHHQS2_k127_4041633_0	1267535.KB906767_gene2153	5.542e-220	704.0	COG0842@1|root,COG1228@1|root,COG0842@2|Bacteria,COG1228@2|Bacteria,3Y750@57723|Acidobacteria	57723|Acidobacteria	QV	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,Amidohydro_1
GDHHQS2_k127_4041633_4	1267535.KB906767_gene2154	1.102e-138	447.0	COG1131@1|root,COG1131@2|Bacteria,3Y4CW@57723|Acidobacteria,2JMQR@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4041633_5	234267.Acid_5493	7.451e-85	286.0	COG0693@1|root,COG0693@2|Bacteria,3Y79I@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS2_k127_4041633_10	29581.BW37_00870	4.636e-06	59.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_4041633_3	1267535.KB906767_gene942	4.309e-160	543.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4041633_1	234267.Acid_5629	2.375e-189	613.0	COG5512@1|root,COG5512@2|Bacteria,3Y7CI@57723|Acidobacteria	57723|Acidobacteria	S	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
GDHHQS2_k127_4041633_7	1267535.KB906767_gene5443	2.292e-56	206.0	COG1214@1|root,COG1214@2|Bacteria,3Y5ED@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GDHHQS2_k127_4041633_8	234267.Acid_3353	1.966e-35	138.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria	57723|Acidobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GDHHQS2_k127_4045079_1	1123242.JH636435_gene1351	2.79e-223	699.0	COG4102@1|root,COG4102@2|Bacteria,2IX3Z@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4045079_3	234267.Acid_4808	1.752e-150	481.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
GDHHQS2_k127_4045079_5	996637.SGM_1386	1.769e-11	73.0	2F9VS@1|root,3425A@2|Bacteria,2H5ZK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4045079_4	1340493.JNIF01000004_gene442	3.999e-114	377.0	COG2321@1|root,COG2321@2|Bacteria,3Y3WQ@57723|Acidobacteria	57723|Acidobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS2_k127_4045079_2	344747.PM8797T_26185	2.742e-158	520.0	COG3119@1|root,COG3119@2|Bacteria	344747.PM8797T_26185|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4045079_0	1340493.JNIF01000004_gene405	2.084e-310	974.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_405500_1	1340493.JNIF01000004_gene855	1.098e-91	313.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_405500_0	1340493.JNIF01000004_gene856	7.098e-92	307.0	COG0745@1|root,COG0745@2|Bacteria	1340493.JNIF01000004_gene856|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_405500_2	886293.Sinac_6924	1.5e-64	231.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_405500_3	886293.Sinac_6923	3.728e-45	171.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_4057306_10	28583.AMAG_01549T0	0.0009052	47.0	COG5103@1|root,KOG1831@2759|Eukaryota,38EGY@33154|Opisthokonta,3NXE7@4751|Fungi	4751|Fungi	K	CCR4-NOT transcription complex subunit	CDC39	GO:0000288,GO:0000289,GO:0000749,GO:0000932,GO:0000956,GO:0001671,GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0007124,GO:0008047,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010603,GO:0010604,GO:0010605,GO:0010607,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0016049,GO:0016070,GO:0016071,GO:0017148,GO:0018130,GO:0019219,GO:0019222,GO:0019236,GO:0019438,GO:0019439,GO:0030014,GO:0030015,GO:0030234,GO:0030447,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0032268,GO:0032269,GO:0032774,GO:0032781,GO:0032784,GO:0032786,GO:0032947,GO:0032968,GO:0032991,GO:0033043,GO:0034243,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0035770,GO:0036464,GO:0040007,GO:0042221,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043254,GO:0043462,GO:0043900,GO:0043902,GO:0044087,GO:0044093,GO:0044182,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0046700,GO:0046999,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051336,GO:0051345,GO:0051716,GO:0051726,GO:0060255,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070783,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0098772,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576,GO:1902115,GO:1902116,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2000112,GO:2000113,GO:2000241,GO:2000243,GO:2001141	-	ko:K12604	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019	-	-	-	CNOT1_CAF1_bind,CNOT1_HEAT,CNOT1_HEAT_N,CNOT1_TTP_bind,DUF3819,Not1
GDHHQS2_k127_4057306_8	278963.ATWD01000001_gene3604	6.537e-08	64.0	COG2304@1|root,COG2304@2|Bacteria,3Y72K@57723|Acidobacteria,2JK9W@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_4057306_4	1340493.JNIF01000003_gene1761	1.066e-149	487.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_4057306_2	1340493.JNIF01000003_gene4593	4.406e-216	696.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS2_k127_4057306_7	1267535.KB906767_gene680	4.881e-25	108.0	COG1983@1|root,COG1983@2|Bacteria,3Y5HA@57723|Acidobacteria	57723|Acidobacteria	KT	Phage shock protein C, PspC	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC,zinc_ribbon_2
GDHHQS2_k127_4057306_5	1340493.JNIF01000003_gene3273	1.104e-37	149.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
GDHHQS2_k127_4057306_3	1288963.ADIS_4720	1.042e-173	570.0	COG3119@1|root,COG3119@2|Bacteria,4P1VX@976|Bacteroidetes,47U8X@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4057306_6	767029.HMPREF9154_0128	6.254e-31	135.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DUJU@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	idhA	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4057306_9	240015.ACP_2091	5.568e-07	59.0	COG2041@1|root,COG2041@2|Bacteria,3Y3AI@57723|Acidobacteria,2JHW2@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_4057306_0	234267.Acid_5331	1.252e-242	765.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_4057306_1	1340493.JNIF01000003_gene1777	1.242e-227	720.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,3Y5BX@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4064115_2	1340493.JNIF01000003_gene2127	8.848e-08	59.0	COG1629@1|root,COG4771@2|Bacteria,3Y6CE@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4064115_1	536019.Mesop_5690	5.708e-25	109.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2UCUJ@28211|Alphaproteobacteria,43KP6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS2_k127_4064115_0	1267535.KB906767_gene2719	4.206e-108	376.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
GDHHQS2_k127_4064115_3	10141.ENSCPOP00000013037	0.0006137	50.0	KOG3864@1|root,KOG3864@2759|Eukaryota,39KU0@33154|Opisthokonta,3BEA0@33208|Metazoa,3D0F3@33213|Bilateria,483YH@7711|Chordata,48Z32@7742|Vertebrata,3J864@40674|Mammalia,35M2T@314146|Euarchontoglires,4PYCU@9989|Rodentia	33208|Metazoa	C	ATP synthase, H transporting, mitochondrial Fo complex, subunit s (factor B)	ATP5S	GO:0000276,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016020,GO:0016043,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042407,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K05752,ko:K07554	ko04810,map04810	-	-	-	ko00000,ko00001	-	-	-	-
GDHHQS2_k127_4073323_0	234267.Acid_6412	1.027e-154	520.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_4073323_3	1123073.KB899245_gene23	6.379e-38	167.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_4073323_2	426117.M446_0916	7.924e-65	256.0	COG3468@1|root,COG3468@2|Bacteria,1RAV6@1224|Proteobacteria,2U6VQ@28211|Alphaproteobacteria,1JXDJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	MU	TIGRFAM outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,NIDO,Pertactin
GDHHQS2_k127_4073323_4	1340493.JNIF01000003_gene3300	4.64e-21	111.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4073323_1	1123276.KB893264_gene4598	4.668e-114	414.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_4075100_0	1123242.JH636435_gene2266	8.98e-190	625.0	COG2010@1|root,COG2010@2|Bacteria,2J24D@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4075100_7	713586.KB900536_gene582	4.566e-18	92.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales	135613|Chromatiales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
GDHHQS2_k127_4075100_5	1123073.KB899245_gene23	9.615e-42	179.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_4075100_6	234267.Acid_6287	2.48e-25	124.0	COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF11,DUF1349,Peptidase_S8,fn3
GDHHQS2_k127_4075100_2	1173024.KI912149_gene6404	2.152e-164	563.0	COG1404@1|root,COG1404@2|Bacteria,1G2F0@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GDHHQS2_k127_4075100_8	1189612.A33Q_4591	1.65e-08	59.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,47JH1@768503|Cytophagia	976|Bacteroidetes	G	PFAM N-acylglucosamine 2-epimerase	ce	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
GDHHQS2_k127_4075100_4	1173021.ALWA01000037_gene3499	3.7e-56	202.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_4075100_1	190650.CC_0139	3.417e-178	587.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,2U4AH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG4772 Outer membrane receptor for Fe3 -dicitrate	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_4075100_3	1121904.ARBP01000013_gene313	1.375e-72	257.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,47JVD@768503|Cytophagia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_4075530_8	1125863.JAFN01000001_gene1447	7.61e-17	86.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_4075530_5	1173024.KI912148_gene2777	9.629e-30	132.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG2203@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G0F6@1117|Cyanobacteria,1JJW3@1189|Stigonemataceae	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	cyaC	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_4075530_1	1267535.KB906767_gene1411	7.688e-143	469.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_4075530_3	234267.Acid_1845	2.812e-106	351.0	COG1694@1|root,COG3956@2|Bacteria,3Y46M@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM MazG family protein	-	-	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
GDHHQS2_k127_4075530_4	1267535.KB906767_gene874	3.716e-93	315.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4075530_7	1340493.JNIF01000004_gene681	1.575e-19	89.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria	57723|Acidobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4075530_0	234267.Acid_1847	6.673e-166	525.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria	57723|Acidobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4075530_6	1268635.Loa_00805	3.428e-23	111.0	COG0697@1|root,COG0697@2|Bacteria,1RJHF@1224|Proteobacteria,1S7YU@1236|Gammaproteobacteria,1JDFH@118969|Legionellales	118969|Legionellales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_4075530_2	234267.Acid_1848	2.268e-109	368.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4079561_1	204669.Acid345_4155	1.771e-55	213.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_4079561_0	497964.CfE428DRAFT_6352	0.0	1170.0	COG1061@1|root,COG2852@1|root,COG4951@1|root,COG1061@2|Bacteria,COG2852@2|Bacteria,COG4951@2|Bacteria,46UU5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559,ResIII
GDHHQS2_k127_4079561_2	886293.Sinac_7090	5.532e-51	197.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4080293_0	234267.Acid_2975	5.651e-133	444.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4080293_2	1340493.JNIF01000004_gene17	2.207e-92	315.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4080293_1	68170.KL590469_gene1670	9.461e-128	419.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E1SB@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	4CL	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_408036_2	234267.Acid_7943	2.044e-05	53.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K03561,ko:K07497	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	HTH_21,Mu-transpos_C,rve,rve_3
GDHHQS2_k127_408036_0	234267.Acid_1944	1.584e-167	537.0	COG2801@1|root,COG2801@2|Bacteria,3Y50C@57723|Acidobacteria	57723|Acidobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32,rve
GDHHQS2_k127_408036_1	864069.MicloDRAFT_00013900	1.206e-24	106.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria,2UQWR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
GDHHQS2_k127_4082721_0	243090.RB12562	1.912e-34	139.0	COG1520@1|root,COG1520@2|Bacteria,2J2RN@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_4091522_0	234267.Acid_5235	1.892e-191	608.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_4091522_8	234267.Acid_5234	4.976e-48	175.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GDHHQS2_k127_4091522_4	864073.HFRIS_014115	5.713e-124	401.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,473UI@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	Short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_4091522_3	1267535.KB906767_gene3950	1.191e-124	411.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria,2JMAT@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4091522_1	525904.Tter_2214	3.973e-178	565.0	COG4948@1|root,COG4948@2|Bacteria,2NR3V@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4091522_5	103690.17132826	1.31e-91	310.0	COG0668@1|root,COG0668@2|Bacteria,1G1I3@1117|Cyanobacteria,1HK89@1161|Nostocales	1117|Cyanobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
GDHHQS2_k127_4091522_2	357808.RoseRS_1977	9.372e-128	420.0	COG2942@1|root,COG2942@2|Bacteria,2G8X6@200795|Chloroflexi,375Z3@32061|Chloroflexia	32061|Chloroflexia	G	PFAM N-acylglucosamine 2-epimerase	-	-	5.1.3.11,5.1.3.8	ko:K01787,ko:K16213	ko00520,map00520	-	R01207,R01445,R10810	RC00289,RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
GDHHQS2_k127_4091522_9	497964.CfE428DRAFT_4747	6.665e-45	169.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_4091522_6	861299.J421_0641	2.995e-72	258.0	COG1304@1|root,COG1304@2|Bacteria,1ZUNQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_4091522_7	1123276.KB893290_gene5273	5.654e-50	192.0	COG1304@1|root,COG1304@2|Bacteria,4NEBK@976|Bacteroidetes,47M15@768503|Cytophagia	976|Bacteroidetes	C	FMN-dependent dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_4094231_9	1123242.JH636434_gene3868	1.039e-95	332.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4094231_12	1183438.GKIL_3942	3.981e-56	201.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
GDHHQS2_k127_4094231_0	234267.Acid_7732	0.0	1881.0	COG0514@1|root,COG0550@1|root,COG0514@2|Bacteria,COG0550@2|Bacteria,3Y363@57723|Acidobacteria	57723|Acidobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12,5.99.1.2	ko:K03169,ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RecQ_Zn_bind
GDHHQS2_k127_4094231_8	211114.JOEF01000025_gene185	4.773e-100	350.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_4094231_19	583355.Caka_2799	5.845e-12	80.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,46VP5@74201|Verrucomicrobia,3K8IM@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS2_k127_4094231_17	234267.Acid_2904	4.948e-28	133.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
GDHHQS2_k127_4094231_4	930169.B5T_00698	8.653e-150	488.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	MA20_16420	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
GDHHQS2_k127_4094231_18	379066.GAU_3293	9.978e-25	108.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
GDHHQS2_k127_4094231_15	234267.Acid_5463	6.545e-36	146.0	COG2318@1|root,COG2318@2|Bacteria,3Y7GV@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4094231_10	234267.Acid_0735	4.281e-78	268.0	2EAQY@1|root,334T6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4094231_16	1484460.JSWG01000004_gene2610	2.265e-34	150.0	2EKYC@1|root,33EMV@2|Bacteria,4NY2E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
GDHHQS2_k127_4094231_11	234267.Acid_5733	4.715e-66	244.0	COG0526@1|root,COG0526@2|Bacteria,3Y40P@57723|Acidobacteria	57723|Acidobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_4094231_6	234267.Acid_0902	8.104e-129	417.0	COG0083@1|root,COG0083@2|Bacteria,3Y2ZV@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS2_k127_4094231_3	234267.Acid_1518	3.005e-151	484.0	COG0673@1|root,COG0673@2|Bacteria,3Y74B@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4094231_1	234267.Acid_7510	1.776e-281	910.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4094231_13	1121875.KB907547_gene3397	1.003e-49	196.0	COG2133@1|root,COG2133@2|Bacteria,4NJ2B@976|Bacteroidetes,1IANY@117743|Flavobacteriia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4094231_5	1340493.JNIF01000003_gene4742	1.565e-131	454.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_4094231_14	234267.Acid_7677	2.247e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_4094231_2	1123248.KB893325_gene1154	2.623e-189	623.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_4094231_7	1267535.KB906767_gene1536	8.404e-117	404.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4104308_0	639030.JHVA01000001_gene590	2.095e-149	502.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4108564_2	926550.CLDAP_17490	8.93e-16	89.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
GDHHQS2_k127_4108564_0	452637.Oter_1864	2.247e-53	198.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
GDHHQS2_k127_4108564_1	670487.Ocepr_1062	2.936e-30	121.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
GDHHQS2_k127_4110698_0	1267535.KB906767_gene3599	1.961e-122	429.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS2_k127_4110972_7	234267.Acid_0823	1.712e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,3Y8IF@57723|Acidobacteria	57723|Acidobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_4110972_8	452637.Oter_4540	2.282e-17	87.0	2BWCC@1|root,34AIN@2|Bacteria,46W54@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
GDHHQS2_k127_4110972_9	1267533.KB906734_gene4040	3.51e-11	68.0	2EN0M@1|root,337VJ@2|Bacteria,3Y5R9@57723|Acidobacteria,2JNZF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4110972_1	234267.Acid_6703	7.111e-106	346.0	COG0176@1|root,COG0176@2|Bacteria,3Y4BN@57723|Acidobacteria	57723|Acidobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS2_k127_4110972_2	1340493.JNIF01000003_gene1489	9.529e-93	311.0	COG0179@1|root,COG0179@2|Bacteria,3Y30T@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GDHHQS2_k127_4110972_4	234267.Acid_1064	4.697e-81	280.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria	57723|Acidobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4110972_0	1267535.KB906767_gene4424	5.971e-242	755.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
GDHHQS2_k127_4110972_3	1267535.KB906767_gene4425	4.305e-86	287.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
GDHHQS2_k127_4110972_5	1123508.JH636450_gene7204	7.765e-67	240.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4110972_6	234267.Acid_4014	8.968e-60	217.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4117641_1	1242864.D187_004259	3.115e-49	199.0	COG2730@1|root,COG3170@1|root,COG2730@2|Bacteria,COG3170@2|Bacteria,1R3TU@1224|Proteobacteria,430KW@68525|delta/epsilon subdivisions,2WVZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
GDHHQS2_k127_4117641_2	1040987.AZUY01000039_gene1121	8.76e-39	152.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,2UEFM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ
GDHHQS2_k127_4117641_0	1340493.JNIF01000004_gene270	0.0	1159.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_4125418_0	1038862.KB893852_gene6725	2.461e-135	433.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JUB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS2_k127_4125418_1	234267.Acid_2848	5.129e-127	415.0	COG1044@1|root,COG1044@2|Bacteria,3Y6ZT@57723|Acidobacteria	57723|Acidobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS2_k127_4125418_2	234267.Acid_0066	5.019e-43	163.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS2_k127_4128657_4	929712.KI912613_gene2528	1.907e-07	63.0	COG2244@1|root,COG2244@2|Bacteria,2HRUX@201174|Actinobacteria,4CTYA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
GDHHQS2_k127_4128657_3	479431.Namu_0742	5.879e-13	80.0	COG2227@1|root,COG2227@2|Bacteria,2GNRH@201174|Actinobacteria,4ETID@85013|Frankiales	201174|Actinobacteria	H	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS2_k127_4128657_0	1267535.KB906767_gene2208	3.913e-149	499.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	204432|Acidobacteriia	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR
GDHHQS2_k127_4128657_1	1215092.PA6_002_00780	1.065e-38	158.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria	1224|Proteobacteria	M	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
GDHHQS2_k127_4128657_2	1267535.KB906767_gene4038	3.593e-34	136.0	COG1596@1|root,COG1596@2|Bacteria,3Y7Z0@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS2_k127_4130140_0	583355.Caka_2045	2.667e-265	862.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_4137572_2	63737.Npun_R3353	1.426e-21	106.0	COG2433@1|root,COG2433@2|Bacteria,1G2BH@1117|Cyanobacteria,1HRA7@1161|Nostocales	1117|Cyanobacteria	S	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS2_k127_4137572_3	215803.DB30_3861	6.44e-19	94.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2YYMZ@29|Myxococcales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS2_k127_4137572_0	1340493.JNIF01000003_gene2346	1.65e-91	314.0	COG1968@1|root,COG1968@2|Bacteria,3Y6B6@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS2_k127_4137572_1	1340493.JNIF01000003_gene2347	7.731e-38	147.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria	57723|Acidobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS2_k127_414126_0	1267535.KB906767_gene4246	4.352e-90	308.0	COG3119@1|root,COG3119@2|Bacteria,3Y679@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_414126_1	593907.Celgi_0443	0.00058	51.0	COG2452@1|root,COG2452@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_17
GDHHQS2_k127_4143335_1	1267535.KB906767_gene2459	2.298e-189	602.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
GDHHQS2_k127_4143335_4	234267.Acid_4014	1.799e-73	261.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4143335_0	234267.Acid_7158	7.825e-213	674.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,3Y6IT@57723|Acidobacteria	57723|Acidobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12
GDHHQS2_k127_4143335_2	234267.Acid_5905	4.267e-121	394.0	COG1082@1|root,COG1082@2|Bacteria,3Y7EJ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_4143335_3	1267535.KB906767_gene4884	7.918e-82	279.0	COG0451@1|root,COG0451@2|Bacteria,3Y3ZG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_4143495_0	391625.PPSIR1_16130	9.84e-148	482.0	COG3039@1|root,COG3039@2|Bacteria,1R70H@1224|Proteobacteria,42Y58@68525|delta/epsilon subdivisions,2WTVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
GDHHQS2_k127_4143495_1	1219045.BV98_002753	2.258e-13	71.0	COG3415@1|root,COG3415@2|Bacteria,1QVAE@1224|Proteobacteria	1224|Proteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
GDHHQS2_k127_4157507_0	1267535.KB906767_gene1167	4.347e-143	475.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4179905_3	1340493.JNIF01000003_gene3891	6.228e-16	79.0	COG1714@1|root,COG1714@2|Bacteria,3Y5I9@57723|Acidobacteria	57723|Acidobacteria	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS2_k127_4179905_0	373903.Hore_19060	3.972e-108	366.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WA5V@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS2_k127_4179905_1	234267.Acid_2701	5.346e-36	145.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_4179905_2	84531.JMTZ01000032_gene300	5.851e-26	125.0	COG3170@1|root,COG3170@2|Bacteria,1R3TU@1224|Proteobacteria,1S63C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the peptidase M12A family	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
GDHHQS2_k127_4183844_0	1340493.JNIF01000003_gene1814	0.0	1455.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4183844_4	981369.JQMJ01000003_gene7087	3.431e-17	95.0	COG0558@1|root,COG0558@2|Bacteria,2I441@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4183844_3	439235.Dalk_1403	1.643e-28	118.0	2E9H4@1|root,333Q5@2|Bacteria,1N6SM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4183844_2	497964.CfE428DRAFT_3672	7.491e-38	150.0	2E958@1|root,333E0@2|Bacteria,46VJR@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4183844_1	313628.LNTAR_07394	4.513e-67	237.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4190384_1	1340493.JNIF01000003_gene1291	1.137e-141	465.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	gnnB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2351	DegT_DnrJ_EryC1
GDHHQS2_k127_4190384_3	234267.Acid_1802	1.487e-101	336.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
GDHHQS2_k127_4190384_2	234267.Acid_7533	2.299e-102	346.0	COG3622@1|root,COG3622@2|Bacteria,3Y5NQ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_4190384_4	379066.GAU_0553	1.206e-37	149.0	COG0110@1|root,COG0110@2|Bacteria,1ZV1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS2_k127_4190384_0	1267535.KB906767_gene1147	2.424e-195	656.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_4190384_5	344747.PM8797T_21003	1.937e-26	112.0	COG3836@1|root,COG3836@2|Bacteria,2IX9H@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_4190408_0	1340493.JNIF01000003_gene1745	4.901e-127	411.0	COG0037@1|root,COG0037@2|Bacteria	2|Bacteria	D	tRNA processing	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	6.3.4.19	ko:K04075,ko:K14058	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
GDHHQS2_k127_4190408_1	234267.Acid_3190	9.357e-121	398.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,3Y2NW@57723|Acidobacteria	57723|Acidobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
GDHHQS2_k127_4190408_2	1267535.KB906767_gene2258	1.03e-86	291.0	COG0036@1|root,COG0036@2|Bacteria,3Y3YN@57723|Acidobacteria,2JIFX@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS2_k127_4190408_3	234267.Acid_3192	1.752e-58	204.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
GDHHQS2_k127_4193006_1	76114.p2A55	2.579e-20	91.0	COG4974@1|root,COG4974@2|Bacteria,1R43B@1224|Proteobacteria,2VNAM@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_4193006_0	1340493.JNIF01000003_gene4529	7.022e-279	896.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4196986_1	1267535.KB906767_gene697	7.016e-72	263.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS2_k127_4196986_0	1205680.CAKO01000038_gene1627	1.165e-92	310.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,2JR5M@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitrile hydratase, alpha chain	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
GDHHQS2_k127_4197630_1	1267535.KB906767_gene941	2.002e-204	656.0	COG3391@1|root,COG3391@2|Bacteria,3Y2QH@57723|Acidobacteria	57723|Acidobacteria	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
GDHHQS2_k127_4197630_3	1122164.JHWF01000022_gene1733	6.55e-07	53.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4197630_4	1415779.JOMH01000001_gene419	4.552e-05	50.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,1X5PX@135614|Xanthomonadales	135614|Xanthomonadales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
GDHHQS2_k127_4197630_0	639030.JHVA01000001_gene1886	9.467e-281	899.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4197630_2	640512.BC1003_3309	1.968e-16	92.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,1KGHM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS2_k127_4199089_0	1198114.AciX9_1463	7.506e-166	548.0	COG0457@1|root,COG0457@2|Bacteria	1198114.AciX9_1463|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4201952_3	338963.Pcar_0807	3.558e-17	93.0	2E41G@1|root,32YY3@2|Bacteria,1N7AU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4201952_2	243164.DET1457	6.029e-28	115.0	2EQ8R@1|root,33HV0@2|Bacteria,2G91J@200795|Chloroflexi,34DHP@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4201952_1	352165.HMPREF7215_1015	9.439e-53	196.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GDHHQS2_k127_4201952_0	1077972.ARGLB_085_01080	6.554e-74	258.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,1W8IH@1268|Micrococcaceae	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
GDHHQS2_k127_4207347_0	401053.AciPR4_1573	1.442e-75	278.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4208930_1	1123242.JH636435_gene1206	1.32e-89	299.0	COG3291@1|root,COG3291@2|Bacteria,2J3CN@203682|Planctomycetes	203682|Planctomycetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4208930_0	1267535.KB906767_gene4837	1.243e-302	957.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4211632_6	234267.Acid_6354	5.486e-28	115.0	COG0809@1|root,COG0809@2|Bacteria,3Y336@57723|Acidobacteria	57723|Acidobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS2_k127_4211632_1	861299.J421_2723	4.819e-196	639.0	COG3258@1|root,COG4993@1|root,COG3258@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.9.1,1.8.2.2	ko:K02030,ko:K17760,ko:K19713	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	Cytochrom_C,Cytochrome_CBB3,PA14,PQQ,PQQ_2,PSCyt3,PSD3,PSD4,PSD5,SBP_bac_3
GDHHQS2_k127_4211632_2	1267535.KB906767_gene216	6.501e-162	518.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_4211632_4	1121920.AUAU01000027_gene1497	3.602e-44	169.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GDHHQS2_k127_4211632_0	1267535.KB906767_gene2442	6.552e-203	638.0	COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria,2JHND@204432|Acidobacteriia	204432|Acidobacteriia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS2_k127_4211632_3	234267.Acid_4392	6.285e-111	365.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_4220309_3	1170562.Cal6303_2768	0.000449	46.0	COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_4220309_2	1267535.KB906767_gene2122	3.203e-136	437.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
GDHHQS2_k127_4220309_1	234267.Acid_6980	2.572e-142	456.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_4220309_0	234267.Acid_5546	3.26e-278	869.0	COG1024@1|root,COG1250@1|root,COG3033@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,COG3033@2|Bacteria,3Y2RB@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GDHHQS2_k127_4223533_0	1123248.KB893325_gene1154	6.608e-189	607.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_4223533_1	234267.Acid_0194	1.083e-171	575.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4223533_2	1108045.GORHZ_109_00020	4.313e-11	68.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS2_k127_4223679_1	1267535.KB906767_gene4991	5.285e-47	174.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,3Y2X1@57723|Acidobacteria,2JHYG@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
GDHHQS2_k127_4223679_2	234267.Acid_1475	3.885e-10	65.0	COG0526@1|root,COG0526@2|Bacteria,3Y8DU@57723|Acidobacteria	57723|Acidobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_4223679_0	234267.Acid_5855	1.266e-133	432.0	COG0579@1|root,COG0579@2|Bacteria,3Y6NN@57723|Acidobacteria	57723|Acidobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
GDHHQS2_k127_4225535_1	5762.XP_002673894.1	4.477e-113	407.0	KOG0597@1|root,KOG1225@1|root,KOG2177@1|root,KOG4659@1|root,KOG0597@2759|Eukaryota,KOG1225@2759|Eukaryota,KOG2177@2759|Eukaryota,KOG4659@2759|Eukaryota	2759|Eukaryota	S	Teneurin transmembrane protein	-	GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0003008,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005886,GO:0006928,GO:0006935,GO:0007275,GO:0007276,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007548,GO:0007588,GO:0008037,GO:0008038,GO:0008045,GO:0008150,GO:0008406,GO:0008584,GO:0008585,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009987,GO:0010171,GO:0010172,GO:0010927,GO:0016020,GO:0016043,GO:0016477,GO:0019953,GO:0022008,GO:0022414,GO:0022607,GO:0030030,GO:0030154,GO:0030182,GO:0030198,GO:0030421,GO:0031175,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032990,GO:0035295,GO:0040011,GO:0040032,GO:0040039,GO:0042221,GO:0042330,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044464,GO:0044703,GO:0045137,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0048468,GO:0048513,GO:0048563,GO:0048565,GO:0048569,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0055123,GO:0060465,GO:0061458,GO:0061564,GO:0070831,GO:0071711,GO:0071840,GO:0071944,GO:0097485,GO:0106030,GO:0120036,GO:0120039,GO:2001197	2.7.7.6	ko:K02599,ko:K03006,ko:K06252,ko:K11997	ko00230,ko00240,ko01100,ko01522,ko03020,ko04151,ko04320,ko04330,ko04510,ko04512,ko04658,ko04919,ko05016,ko05020,ko05165,ko05168,ko05169,ko05200,ko05206,ko05224,map00230,map00240,map01100,map01522,map03020,map04151,map04320,map04330,map04510,map04512,map04658,map04919,map05016,map05020,map05165,map05168,map05169,map05200,map05206,map05224	M00180,M00682	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko00536,ko01000,ko03021,ko03400,ko04121,ko04516	-	-	-	EGF_2,NHL,Pkinase,TIG
GDHHQS2_k127_4225535_0	1123242.JH636435_gene1109	5.503e-163	518.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
GDHHQS2_k127_4225535_2	765913.ThidrDRAFT_1143	1.681e-09	59.0	COG3415@1|root,COG3415@2|Bacteria,1QWT2@1224|Proteobacteria,1T5A1@1236|Gammaproteobacteria,1X2VP@135613|Chromatiales	1236|Gammaproteobacteria	L	PFAM Transposase, Rhodopirellula-type	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS2_k127_4225731_3	1340493.JNIF01000003_gene1290	9.575e-118	388.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784,ko:K13318,ko:K13322,ko:K16439,ko:K19857	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793,M00798,M00799,M00800	R00291,R02984,R06436,R06513,R06629,R11042,R11047	RC00182,RC00261,RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_4225731_5	234267.Acid_1803	1.342e-81	278.0	COG0500@1|root,COG2226@2|Bacteria,3Y8WR@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_4225731_4	234267.Acid_2804	1.403e-108	366.0	COG4299@1|root,COG4299@2|Bacteria,3Y2J9@57723|Acidobacteria	57723|Acidobacteria	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
GDHHQS2_k127_4225731_6	1340493.JNIF01000003_gene1338	4.55e-62	224.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_4225731_12	1121957.ATVL01000012_gene616	7.68e-34	141.0	COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4225731_8	234267.Acid_4093	1.405e-43	171.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_4225731_9	234267.Acid_4092	9.528e-42	160.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_4225731_13	234267.Acid_0312	5.845e-31	128.0	COG1595@1|root,COG1595@2|Bacteria,3Y2V2@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4225731_0	1340493.JNIF01000004_gene778	1.194e-236	747.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_4225731_16	1267533.KB906735_gene4580	0.0002003	45.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JP0E@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4225731_2	1122605.KB893645_gene1148	3.898e-120	399.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1IS5G@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4225731_10	234267.Acid_5749	6.61e-41	168.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_4225731_1	234267.Acid_6265	3.413e-123	410.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_4225731_15	765914.ThisiDRAFT_0043	1.026e-08	66.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,1WVWK@135613|Chromatiales	135613|Chromatiales	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_4225731_7	272123.Anacy_2153	1.132e-46	180.0	COG2253@1|root,COG2253@2|Bacteria,1G952@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS2_k127_4225731_11	886293.Sinac_1385	1.524e-35	144.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AbiEi_4
GDHHQS2_k127_4232889_0	1340493.JNIF01000004_gene873	2.835e-255	810.0	COG1629@1|root,COG4771@2|Bacteria,3Y36N@57723|Acidobacteria	57723|Acidobacteria	P	PFAM TonB-dependent Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_4232889_6	1347392.CCEZ01000075_gene3052	1.723e-10	74.0	COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,25AME@186801|Clostridia,36GSZ@31979|Clostridiaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_4232889_2	756272.Plabr_4313	3.318e-98	343.0	COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4232889_1	1123278.KB893522_gene2536	5.785e-138	451.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4232889_5	1329250.WOSG25_061140	1.096e-16	89.0	COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,4HIQE@91061|Bacilli,4AZ16@81850|Leuconostocaceae	91061|Bacilli	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
GDHHQS2_k127_4232889_4	1379270.AUXF01000005_gene493	9.886e-36	143.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	XK27_00825	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_4232889_3	234267.Acid_2502	1.577e-68	241.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_4233309_0	1340493.JNIF01000004_gene570	5e-324	1008.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4233309_1	1340493.JNIF01000004_gene569	1.081e-218	686.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4234687_0	1340493.JNIF01000004_gene1048	7.64e-225	704.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4234687_1	313596.RB2501_10327	3.729e-19	94.0	2ENME@1|root,33G8R@2|Bacteria,4PFKB@976|Bacteroidetes,1I7CD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4238844_0	1298865.H978DRAFT_3096	4.169e-154	500.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt_2	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_4243063_7	1192759.AKIB01000034_gene3212	1.053e-47	177.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TTBP@28211|Alphaproteobacteria,2K14S@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_4243063_4	1267535.KB906767_gene2417	1.785e-84	286.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS2_k127_4243063_9	234267.Acid_1859	3.143e-25	112.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria	57723|Acidobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS2_k127_4243063_2	1267535.KB906767_gene2419	2.234e-194	621.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS2_k127_4243063_6	1267535.KB906767_gene3052	3.011e-61	220.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Y7@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4243063_5	926690.KE386573_gene1278	5.916e-72	254.0	COG0434@1|root,arCOG01982@2157|Archaea,2XT9I@28890|Euryarchaeota,23T8W@183963|Halobacteria	183963|Halobacteria	S	photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
GDHHQS2_k127_4243063_3	517418.Ctha_0316	2.528e-86	303.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340,Gln_amidase
GDHHQS2_k127_4243063_0	886293.Sinac_4981	2.362e-242	779.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
GDHHQS2_k127_4243063_1	1396418.BATQ01000076_gene703	1.375e-200	637.0	COG3391@1|root,COG3391@2|Bacteria,46UTG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4243063_8	234267.Acid_7487	7.68e-37	145.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GDHHQS2_k127_4243063_10	1108045.GORHZ_109_00030	4.494e-12	74.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4245422_0	382464.ABSI01000010_gene3258	4.824e-205	673.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4245584_12	1340493.JNIF01000003_gene1788	4.287e-07	53.0	COG0188@1|root,COG0188@2|Bacteria,3Y2G5@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS2_k127_4245584_1	234267.Acid_1992	1.135e-246	779.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4245584_4	290397.Adeh_2993	4.464e-142	458.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_4245584_9	1123508.JH636439_gene362	8.507e-15	76.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
GDHHQS2_k127_4245584_10	1123508.JH636439_gene362	2.302e-14	76.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
GDHHQS2_k127_4245584_8	1123073.KB899241_gene3463	1.122e-30	141.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N,GHL10,Polysacc_deac_1
GDHHQS2_k127_4245584_7	234267.Acid_2812	4.26e-38	146.0	COG0822@1|root,COG0822@2|Bacteria,3Y4B9@57723|Acidobacteria	57723|Acidobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS2_k127_4245584_6	1267535.KB906767_gene424	8.411e-42	157.0	COG0494@1|root,COG0494@2|Bacteria,3Y55X@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS2_k127_4245584_3	234267.Acid_2807	1.274e-177	572.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_4245584_0	1340493.JNIF01000003_gene4160	9.344e-289	904.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_4245584_2	1123242.JH636434_gene5120	6.799e-232	734.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
GDHHQS2_k127_4245584_11	240016.ABIZ01000001_gene1085	9.93e-09	61.0	COG3385@1|root,COG3385@2|Bacteria,46W0E@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS2_k127_4245584_5	234267.Acid_2975	2.526e-54	198.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4247513_2	443144.GM21_0456	9.005e-17	81.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2WKJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	lolD-2	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4247513_0	269799.Gmet_1517	5.792e-155	522.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MV	MacB-like periplasmic core domain	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_4247513_1	404380.Gbem_0435	3.532e-35	146.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,43VVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
GDHHQS2_k127_4247513_3	1121434.AULY01000012_gene2860	1.98e-06	61.0	2E2R6@1|root,32XTS@2|Bacteria,1R2HY@1224|Proteobacteria,43DEI@68525|delta/epsilon subdivisions,2WRQH@28221|Deltaproteobacteria,2MBMJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4250572_2	497964.CfE428DRAFT_1847	2.362e-30	123.0	COG1028@1|root,COG1028@2|Bacteria	497964.CfE428DRAFT_1847|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4250572_1	234267.Acid_4807	7.83e-88	299.0	COG0705@1|root,COG0705@2|Bacteria,3Y5A9@57723|Acidobacteria	57723|Acidobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_4250572_0	1267535.KB906767_gene1497	9.304e-111	363.0	COG2120@1|root,COG2120@2|Bacteria,3Y3NP@57723|Acidobacteria,2JIEH@204432|Acidobacteriia	204432|Acidobacteriia	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS2_k127_4250572_3	1340493.JNIF01000003_gene4538	2.669e-19	90.0	2A5Y1@1|root,30UQ2@2|Bacteria,3Y7MH@57723|Acidobacteria	57723|Acidobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS2_k127_4252992_0	234267.Acid_0526	1.94e-173	550.0	COG0460@1|root,COG0460@2|Bacteria,3Y2VY@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS2_k127_4252992_1	234267.Acid_0533	2.292e-15	82.0	290CR@1|root,2ZN27@2|Bacteria,3Y8Z2@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4256368_5	388399.SSE37_16973	7.329e-10	69.0	2C6TH@1|root,33MU1@2|Bacteria,1NT5C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4256368_1	234267.Acid_3244	1.452e-114	377.0	COG2133@1|root,COG2133@2|Bacteria,3Y7A7@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_4256368_0	234267.Acid_5326	2.245e-133	441.0	COG1082@1|root,COG1082@2|Bacteria,3Y6CF@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_4256368_4	316274.Haur_2614	3.426e-56	205.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,3759E@32061|Chloroflexia	316274.Haur_2614|-	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4256368_3	1340493.JNIF01000003_gene1949	1.164e-99	333.0	COG0526@1|root,COG0526@2|Bacteria,3Y64J@57723|Acidobacteria	57723|Acidobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_4256368_2	1382359.JIAL01000001_gene1345	2.472e-108	355.0	COG1741@1|root,COG1741@2|Bacteria,3Y4MS@57723|Acidobacteria,2JKK8@204432|Acidobacteriia	204432|Acidobacteriia	S	Pirin C-terminal cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
GDHHQS2_k127_4258307_4	575540.Isop_2455	3.579e-26	109.0	COG1961@1|root,COG1961@2|Bacteria,2IYJH@203682|Planctomycetes	203682|Planctomycetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_4258307_1	909663.KI867149_gene3232	4.913e-38	149.0	29X4W@1|root,30ITV@2|Bacteria,1PD23@1224|Proteobacteria,437WM@68525|delta/epsilon subdivisions,2X36A@28221|Deltaproteobacteria,2MS4K@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2924
GDHHQS2_k127_4258307_2	1340493.JNIF01000003_gene2650	4.2e-35	150.0	COG1629@1|root,COG4771@2|Bacteria,3Y980@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4258307_0	1340493.JNIF01000003_gene2650	8.054e-92	320.0	COG1629@1|root,COG4771@2|Bacteria,3Y980@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4258307_3	1340493.JNIF01000004_gene597	5.215e-30	124.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4260623_0	234267.Acid_2031	2.195e-188	614.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
GDHHQS2_k127_4260623_3	221103.XP_007859414.1	1.812e-22	113.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3V5XN@5204|Basidiomycota,22D2C@155619|Agaricomycetes,3W9Q7@5338|Agaricales	4751|Fungi	M	Multiple ankyrin repeats single kh domain	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
GDHHQS2_k127_4260623_2	1340493.JNIF01000003_gene1475	2.205e-94	324.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4260623_4	234267.Acid_3279	1.949e-19	93.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	ASH,CarboxypepD_reg,DUF11,FlgD_ig,HYR,Laminin_G_3,Plug,TonB_dep_Rec
GDHHQS2_k127_4260623_5	768671.ThimaDRAFT_4529	1.375e-10	63.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
GDHHQS2_k127_4260623_1	1123508.JH636450_gene7160	1.04e-134	459.0	COG1506@1|root,COG1506@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS2_k127_4262348_0	1123508.JH636439_gene874	8.44e-139	456.0	COG2936@1|root,COG2936@2|Bacteria,2IYPJ@203682|Planctomycetes	203682|Planctomycetes	E	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_4262348_1	1267535.KB906767_gene3318	2.478e-113	379.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS2_k127_4262348_2	234267.Acid_6358	5.532e-64	225.0	COG0637@1|root,COG0637@2|Bacteria,3Y7V3@57723|Acidobacteria	57723|Acidobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_4262348_6	316274.Haur_4259	6.001e-07	63.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_4262348_4	1267535.KB906767_gene305	6.45e-43	162.0	2FHZ5@1|root,349S3@2|Bacteria,3Y8GI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4262348_3	234267.Acid_6487	2.899e-54	197.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_4263701_1	504472.Slin_4565	1.159e-82	284.0	COG1228@1|root,COG1228@2|Bacteria,4NKV0@976|Bacteroidetes,47TDT@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_4263701_0	234267.Acid_3073	1.721e-150	479.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_426855_0	1267535.KB906767_gene3825	2.017e-140	473.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4273377_2	1123024.AUII01000022_gene110	8.275e-27	115.0	COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4EF7E@85010|Pseudonocardiales	201174|Actinobacteria	LT	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
GDHHQS2_k127_4273377_1	521045.Kole_0088	1.759e-42	162.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
GDHHQS2_k127_4273377_0	204669.Acid345_0328	8.787e-94	316.0	COG3534@1|root,COG3534@2|Bacteria,3Y48A@57723|Acidobacteria,2JKQ1@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS2_k127_4278840_1	234267.Acid_0947	1.596e-62	239.0	COG4995@1|root,COG4995@2|Bacteria,3Y4TR@57723|Acidobacteria	57723|Acidobacteria	O	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
GDHHQS2_k127_4278840_3	1380356.JNIK01000018_gene662	6.91e-05	53.0	COG0265@1|root,COG0265@2|Bacteria,2IJFX@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4278840_0	1340493.JNIF01000003_gene4575	1.556e-177	587.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4278840_2	1210884.HG799465_gene11550	4.326e-20	93.0	COG4102@1|root,COG4102@2|Bacteria,2IX0F@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4279263_5	234267.Acid_0376	1.053e-17	87.0	COG0454@1|root,COG0456@2|Bacteria,3Y3VJ@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_4279263_1	234267.Acid_7248	1.22e-143	477.0	COG2041@1|root,COG2041@2|Bacteria,3Y7UP@57723|Acidobacteria	57723|Acidobacteria	C	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GDHHQS2_k127_4279263_2	1340493.JNIF01000004_gene905	7.923e-125	411.0	COG3437@1|root,COG3437@2|Bacteria,3Y6BB@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
GDHHQS2_k127_4279263_0	1340493.JNIF01000004_gene896	3.875e-266	830.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
GDHHQS2_k127_4279263_3	452637.Oter_1883	3.414e-50	201.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_4289037_4	234267.Acid_6051	6.637e-06	57.0	COG1075@1|root,COG1075@2|Bacteria,3Y8K4@57723|Acidobacteria	57723|Acidobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4289037_3	1267533.KB906740_gene137	1.61e-25	115.0	29Y1S@1|root,30JUQ@2|Bacteria,3Y90C@57723|Acidobacteria,2JNWN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4289037_0	1340493.JNIF01000004_gene791	1.416e-177	572.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene791|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4289037_1	448385.sce6263	1.524e-105	358.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
GDHHQS2_k127_4289037_2	309807.SRU_0977	8.176e-72	260.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4299821_0	234267.Acid_5310	2.587e-188	597.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_4299821_1	1267535.KB906767_gene4097	1.032e-28	120.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria,2JI3J@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4303177_2	234267.Acid_5009	6.856e-20	91.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4303177_0	234267.Acid_3690	7.459e-209	690.0	COG1629@1|root,COG1629@2|Bacteria,3Y9AK@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_4303177_1	1340493.JNIF01000003_gene1466	1.35e-60	215.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20866,ko:K21063	ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00947,R05287,R07280	RC00017,RC00078,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
GDHHQS2_k127_4307916_3	1340493.JNIF01000003_gene2956	3.711e-37	143.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
GDHHQS2_k127_4307916_0	234267.Acid_2984	9.539e-198	630.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	2|Bacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	dgoD	GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.1.2.21,4.2.1.6	ko:K01631,ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R01064,R03033	RC00307,RC00435,RC00543	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b4478,iB21_1397.B21_03519,iBWG_1329.BWG_3382,iEC042_1314.EC042_4048,iEC55989_1330.EC55989_4161,iECBD_1354.ECBD_0011,iECB_1328.ECB_03575,iECDH10B_1368.ECDH10B_3878,iECDH1ME8569_1439.ECDH1ME8569_3579,iECD_1391.ECD_03575,iECIAI1_1343.ECIAI1_3870,iECO103_1326.ECO103_4466,iECO111_1330.ECO111_4519,iECSE_1348.ECSE_3978,iECUMN_1333.ECUMN_4223,iECW_1372.ECW_m3991,iEKO11_1354.EKO11_0011,iETEC_1333.ETEC_3982,iEcDH1_1363.EcDH1_0011,iEcE24377_1341.EcE24377A_4201,iEcSMS35_1347.EcSMS35_4057,iEcolC_1368.EcolC_0011,iJO1366.b4478,iWFL_1372.ECW_m3991,iY75_1357.Y75_RS18645	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4307916_2	234267.Acid_2985	4.715e-99	334.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4307916_6	234267.Acid_7664	2.552e-11	70.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4307916_5	1340493.JNIF01000003_gene3561	6.382e-12	71.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4307916_7	1267533.KB906736_gene1155	1.365e-05	53.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZC@57723|Acidobacteria,2JK8R@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4307916_8	1267535.KB906767_gene942	1.502e-05	48.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4307916_4	1340493.JNIF01000003_gene4600	5.407e-22	100.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4307916_1	1340493.JNIF01000003_gene3949	2.219e-168	533.0	COG0463@1|root,COG0463@2|Bacteria,3Y30V@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_4312277_0	234267.Acid_0320	2.804e-125	405.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
GDHHQS2_k127_4312277_1	234267.Acid_0321	9.971e-43	157.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
GDHHQS2_k127_4312277_2	234267.Acid_0322	3.891e-42	156.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS2_k127_4312277_5	234267.Acid_0323	2.542e-32	130.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS2_k127_4312277_3	234267.Acid_0324	5.488e-41	157.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GDHHQS2_k127_4312277_4	1156937.MFUM_1010089	6.925e-39	154.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_4312277_6	1267535.KB906767_gene110	1.901e-24	106.0	2DF3Q@1|root,2ZQCR@2|Bacteria,3Y8YJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4312277_7	1267535.KB906767_gene2486	1.842e-23	101.0	2DWVU@1|root,3424P@2|Bacteria,3Y8CU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4313304_0	706587.Desti_5093	5.92e-230	730.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS2_k127_4313304_3	351160.LRC120	7.16e-58	218.0	arCOG02342@1|root,arCOG02342@2157|Archaea	2157|Archaea	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,HisKA_2,MCPsignal,PAS_3,PAS_9,dCache_1,sCache_3_3
GDHHQS2_k127_4313304_2	443144.GM21_3146	1.023e-76	281.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
GDHHQS2_k127_4313304_4	338966.Ppro_3011	3.364e-47	177.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,43CDX@68525|delta/epsilon subdivisions,2X7PU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4313304_5	309798.COPRO5265_0032	2.009e-27	130.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1UJ0B@1239|Firmicutes,25ESZ@186801|Clostridia,42J5S@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_3,PAS_4
GDHHQS2_k127_4313304_1	1521187.JPIM01000079_gene1531	8.001e-90	327.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3614@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3614@2|Bacteria,2GBJ0@200795|Chloroflexi,37648@32061|Chloroflexia	32061|Chloroflexia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,MASE1,PAS_4,Response_reg
GDHHQS2_k127_4316386_4	1267535.KB906767_gene3195	1.876e-32	128.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS2_k127_4316386_0	234267.Acid_0016	4.116e-107	353.0	COG1192@1|root,COG1192@2|Bacteria,3Y2Y2@57723|Acidobacteria	57723|Acidobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS2_k127_4316386_2	1340493.JNIF01000003_gene2685	1.74e-95	322.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS2_k127_4316386_1	886293.Sinac_5845	1.16e-100	337.0	COG1453@1|root,COG1453@2|Bacteria,2IZF3@203682|Planctomycetes	203682|Planctomycetes	S	aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_4316386_3	1340493.JNIF01000003_gene2669	5.76e-63	219.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS2_k127_4319570_3	886293.Sinac_5601	1.229e-26	116.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4319570_5	112098.XP_008620264.1	0.0001851	48.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,F-box,Ion_trans
GDHHQS2_k127_4319570_4	632335.Calkr_1515	3.744e-22	102.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
GDHHQS2_k127_4319570_2	1170562.Cal6303_2679	1.124e-40	166.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HRXU@1161|Nostocales	1117|Cyanobacteria	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
GDHHQS2_k127_4319570_1	1267535.KB906767_gene2709	2.158e-67	230.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS2_k127_4319570_0	1267535.KB906767_gene2708	1.858e-75	255.0	COG0049@1|root,COG0049@2|Bacteria,3Y3FF@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS2_k127_432853_0	1340493.JNIF01000004_gene924	1.786e-161	524.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,3Y2FR@57723|Acidobacteria	57723|Acidobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
GDHHQS2_k127_432853_1	1340493.JNIF01000004_gene925	7.709e-78	271.0	COG1305@1|root,COG1305@2|Bacteria,3Y3J9@57723|Acidobacteria	57723|Acidobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
GDHHQS2_k127_432853_3	946483.Cenrod_0650	8.179e-32	138.0	28PGD@1|root,2ZC77@2|Bacteria,1RBAH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_432853_2	1340493.JNIF01000003_gene1861	5.636e-40	155.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_4331425_0	234267.Acid_0848	5.287e-270	841.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,3Y2SH@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GDHHQS2_k127_4331425_2	1120956.JHZK01000010_gene2771	3.63e-33	143.0	COG4948@1|root,COG4948@2|Bacteria,1NJ4H@1224|Proteobacteria,2U0F7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4331425_1	411902.CLOBOL_01842	7.003e-43	175.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,21ZBJ@1506553|Lachnoclostridium	186801|Clostridia	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4331425_3	401053.AciPR4_1567	4.885e-17	85.0	COG1629@1|root,COG1629@2|Bacteria,3Y39P@57723|Acidobacteria,2JIP0@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4338306_11	1454202.PPBDW_140160___1	5.418e-05	46.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4338306_1	234267.Acid_7337	1.017e-267	841.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	yuxL	-	3.4.14.5,3.4.19.1	ko:K01278,ko:K01303	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_4338306_3	234267.Acid_5385	3.125e-129	423.0	COG1063@1|root,COG1063@2|Bacteria,3Y6GC@57723|Acidobacteria	57723|Acidobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_4338306_0	1340493.JNIF01000003_gene4374	3.92e-315	985.0	COG0058@1|root,COG0058@2|Bacteria,3Y65H@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS2_k127_4338306_7	1340493.JNIF01000003_gene4373	1.9e-49	184.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS2_k127_4338306_2	234267.Acid_7159	4.581e-227	713.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,3Y2Y4@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25,4.2.1.10	ko:K00014,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
GDHHQS2_k127_4338306_4	649747.HMPREF0083_05238	4.877e-106	353.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4338306_9	324057.Pjdr2_0828	3.783e-48	184.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,26TCG@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter permease	M1-956	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS2_k127_4338306_6	1423321.AS29_06450	4.23e-54	199.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus	91061|Bacilli	S	transport system, permease component	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS2_k127_4338306_5	1173021.ALWA01000039_gene1829	3.003e-89	312.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,PrsW-protease,zinc_ribbon_2
GDHHQS2_k127_4338306_10	1121085.AUCI01000001_gene3699	7.978e-28	127.0	COG0329@1|root,COG0329@2|Bacteria,1UBSQ@1239|Firmicutes,4IN7W@91061|Bacilli,1ZMZY@1386|Bacillus	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
GDHHQS2_k127_434124_2	234267.Acid_3957	9.831e-14	74.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
GDHHQS2_k127_434124_0	392499.Swit_1900	4.943e-254	801.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K1V6@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_434124_1	1267535.KB906767_gene1323	6.068e-15	75.0	COG2346@1|root,COG2346@2|Bacteria,3Y8TC@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS2_k127_434176_0	1242864.D187_008417	5.44e-42	171.0	COG0793@1|root,COG0793@2|Bacteria,1RCVK@1224|Proteobacteria	1224|Proteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_4342202_2	1189612.A33Q_2797	0.0001109	53.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_4342202_0	234267.Acid_4320	6.117e-85	288.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4342202_1	234267.Acid_4321	2.967e-75	267.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_4348653_0	234267.Acid_7763	1.995e-270	842.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS2_k127_4348653_3	234267.Acid_7762	4.56e-51	190.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria	57723|Acidobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
GDHHQS2_k127_4348653_2	234267.Acid_7135	7.004e-149	486.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria	57723|Acidobacteria	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GDHHQS2_k127_4348653_1	234267.Acid_7136	1.014e-168	538.0	COG0743@1|root,COG0743@2|Bacteria,3Y30J@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS2_k127_4348885_4	251221.35212645	5.183e-13	75.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
GDHHQS2_k127_4348885_2	1267535.KB906767_gene4790	4.216e-94	320.0	COG5285@1|root,COG5285@2|Bacteria,3Y7AJ@57723|Acidobacteria	57723|Acidobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
GDHHQS2_k127_4348885_0	234267.Acid_6381	8.904e-127	415.0	COG0859@1|root,COG0859@2|Bacteria,3Y6NF@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_4348885_1	234267.Acid_6383	1.347e-100	341.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_4348885_3	1267535.KB906767_gene442	2.155e-57	212.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJJZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_4355163_3	1267535.KB906767_gene5119	5.141e-12	66.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria,2JI4V@204432|Acidobacteriia	204432|Acidobacteriia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS2_k127_4355163_2	234267.Acid_7821	9.403e-46	172.0	COG1555@1|root,COG1555@2|Bacteria,3Y869@57723|Acidobacteria	57723|Acidobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS2_k127_4355163_0	234267.Acid_7820	2.125e-142	469.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_4355163_1	234267.Acid_7819	9.669e-79	270.0	COG2755@1|root,COG2755@2|Bacteria,3Y4BD@57723|Acidobacteria	57723|Acidobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_4360105_0	1340493.JNIF01000003_gene1800	0.0	1687.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4364592_3	1340493.JNIF01000003_gene2300	9.015e-98	326.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_4364592_4	234267.Acid_1719	3.964e-73	257.0	COG0136@1|root,COG0136@2|Bacteria,3Y395@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_4364592_6	1340493.JNIF01000003_gene2302	2.374e-51	187.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria	57723|Acidobacteria	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
GDHHQS2_k127_4364592_2	1340493.JNIF01000003_gene2303	3.76e-99	336.0	COG1466@1|root,COG1466@2|Bacteria,3Y2XE@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS2_k127_4364592_7	58344.JOEL01000013_gene6620	1.59e-48	186.0	COG0793@1|root,COG0793@2|Bacteria,2GNJA@201174|Actinobacteria	201174|Actinobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
GDHHQS2_k127_4364592_1	234267.Acid_3331	4.002e-174	555.0	COG0673@1|root,COG0673@2|Bacteria,3Y2KV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4364592_10	234267.Acid_5460	7.264e-06	52.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS2_k127_4364592_5	234267.Acid_1562	1.639e-51	191.0	COG0526@1|root,COG0526@2|Bacteria,3Y4UN@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS2_k127_4364592_0	234267.Acid_1055	7.837e-229	717.0	COG0277@1|root,COG0277@2|Bacteria,3Y68N@57723|Acidobacteria	57723|Acidobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS2_k127_4364592_8	573413.Spirs_2722	8.605e-41	163.0	COG0407@1|root,COG0407@2|Bacteria,2JAKQ@203691|Spirochaetes	203691|Spirochaetes	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS2_k127_4364592_9	1122919.KB905594_gene4240	1.875e-12	70.0	COG1053@1|root,COG1053@2|Bacteria,1TSG9@1239|Firmicutes,4HE2J@91061|Bacilli,26QE0@186822|Paenibacillaceae	91061|Bacilli	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_436994_0	234267.Acid_5676	3.25e-185	604.0	COG0515@1|root,COG1262@1|root,COG1506@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	1.14.99.50,2.7.11.1	ko:K01990,ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	M00254	R11013	RC03323,RC03324	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1	-	-	FGE-sulfatase,Peptidase_S15,Pkinase
GDHHQS2_k127_436994_1	234267.Acid_0871	1.008e-49	193.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	234267.Acid_0871|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_436994_2	1340493.JNIF01000004_gene281	2.599e-37	151.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene281|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_437076_0	1340493.JNIF01000004_gene284	9.74e-98	336.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase,Hepar_II_III,Hepar_II_III_N
GDHHQS2_k127_437076_1	379066.GAU_0974	6.456e-45	170.0	29KMP@1|root,307IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
GDHHQS2_k127_437076_4	379066.GAU_0974	0.0006667	44.0	29KMP@1|root,307IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
GDHHQS2_k127_437076_2	1340493.JNIF01000004_gene1098	4.468e-40	152.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_437076_3	1340493.JNIF01000004_gene369	4.984e-22	101.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
GDHHQS2_k127_4375013_2	1267533.KB906734_gene3997	4.41e-103	338.0	COG0782@1|root,COG0782@2|Bacteria,3Y351@57723|Acidobacteria	57723|Acidobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS2_k127_4375013_0	234267.Acid_5824	4.391e-163	518.0	COG0564@1|root,COG0564@2|Bacteria,3Y446@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
GDHHQS2_k127_4375013_7	1170562.Cal6303_5638	1.547e-26	114.0	COG3464@1|root,COG3464@2|Bacteria,1G6BF@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4375013_3	1340493.JNIF01000003_gene2887	3.758e-88	298.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HH@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4375013_4	1340493.JNIF01000003_gene1414	4.414e-73	258.0	COG2367@1|root,COG2367@2|Bacteria,3Y3UF@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS2_k127_4375013_1	234267.Acid_0957	3.967e-157	502.0	COG2255@1|root,COG2255@2|Bacteria,3Y2RP@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS2_k127_4375013_5	1120973.AQXL01000119_gene525	8.753e-36	145.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,278HS@186823|Alicyclobacillaceae	91061|Bacilli	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GDHHQS2_k127_4375013_6	745310.G432_13940	5.068e-32	133.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,2TUNP@28211|Alphaproteobacteria,2K1AW@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_4375910_1	234267.Acid_1263	3.809e-162	516.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_4375910_0	234267.Acid_1264	1.058e-171	546.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_4375910_2	234267.Acid_1265	1.54e-140	452.0	COG1562@1|root,COG1562@2|Bacteria,3Y3ZV@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Squalene phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
GDHHQS2_k127_4375910_3	1267535.KB906767_gene2365	8.907e-38	148.0	COG1562@1|root,COG1562@2|Bacteria,3Y3YX@57723|Acidobacteria,2JIHF@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
GDHHQS2_k127_4376427_3	56110.Oscil6304_1502	2.733e-20	94.0	COG3950@1|root,COG3950@2|Bacteria,1G2F1@1117|Cyanobacteria,1HDAP@1150|Oscillatoriales	1117|Cyanobacteria	S	ATP-binding protein involved in virulence	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
GDHHQS2_k127_4376427_1	1267535.KB906767_gene218	6.979e-75	256.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4376427_2	1267535.KB906767_gene310	6.993e-71	245.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_4376427_0	641524.ADICYQ_4182	1.908e-139	458.0	2DVXG@1|root,33XK4@2|Bacteria	2|Bacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4377737_0	861299.J421_0764	3.359e-90	310.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_4377737_1	1379698.RBG1_1C00001G0718	1.884e-66	246.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_4377737_4	1267535.KB906767_gene5194	1.177e-45	171.0	COG0494@1|root,COG0494@2|Bacteria,3Y4N9@57723|Acidobacteria,2JJ9X@204432|Acidobacteriia	204432|Acidobacteriia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_4377737_3	204669.Acid345_2119	2.628e-47	177.0	COG0727@1|root,COG0727@2|Bacteria,3Y4VW@57723|Acidobacteria,2JJKG@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
GDHHQS2_k127_4377737_2	1340493.JNIF01000003_gene3832	2.178e-57	203.0	COG1225@1|root,COG1225@2|Bacteria,3Y7Y4@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS2_k127_4377737_5	344747.PM8797T_02274	5.643e-44	163.0	COG1028@1|root,COG1028@2|Bacteria,2IYVH@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_4382576_0	1267535.KB906767_gene3483	7.272e-237	762.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4382576_1	1163617.SCD_n00861	5.94e-193	624.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GDHHQS2_k127_4383092_2	234267.Acid_5009	4.311e-68	246.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4383092_1	1397666.RS24_00079	3.011e-122	408.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,4BT88@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4383092_0	1267535.KB906767_gene4512	2.07e-292	921.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_438333_0	1340493.JNIF01000003_gene3022	2.731e-86	299.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_438333_1	234267.Acid_7664	4.099e-80	290.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_438333_2	1267535.KB906767_gene3483	2.359e-21	95.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_440037_1	234267.Acid_2549	2.01e-84	284.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria	57723|Acidobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS2_k127_440037_0	1267535.KB906767_gene3781	2.51e-117	391.0	COG0531@1|root,COG0531@2|Bacteria,3Y4PR@57723|Acidobacteria,2JJPB@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
GDHHQS2_k127_440037_2	234267.Acid_5356	2.761e-55	213.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_440037_3	1340493.JNIF01000003_gene1957	7.654e-11	67.0	2DB97@1|root,32TX2@2|Bacteria,3Y59S@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4402989_1	756272.Plabr_2687	5.907e-113	371.0	COG3119@1|root,COG3119@2|Bacteria,2J26D@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_4402989_0	690850.Desaf_2604	2.155e-153	497.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,431Z2@68525|delta/epsilon subdivisions,2WWQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS2_k127_4407034_0	1121090.KB894687_gene833	2.869e-77	263.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus	91061|Bacilli	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_4407034_1	384765.SIAM614_09638	4.33e-24	118.0	COG0747@1|root,COG0747@2|Bacteria,1MUEH@1224|Proteobacteria,2TSNC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_4407206_0	1379270.AUXF01000002_gene1393	5.575e-48	177.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS2_k127_4407206_1	234267.Acid_3104	1.136e-12	76.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4420809_2	335543.Sfum_1623	3.66e-49	191.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_4420809_0	1267533.KB906734_gene4380	5.589e-199	666.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,3Y6YV@57723|Acidobacteria,2JKEW@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_4420809_1	1396141.BATP01000002_gene4837	1.131e-52	198.0	COG3828@1|root,COG3828@2|Bacteria,46V1D@74201|Verrucomicrobia,2IUS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS2_k127_4421953_2	582515.KR51_00020250	2.198e-07	55.0	COG2380@1|root,COG2380@2|Bacteria,1GDAS@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4421953_1	99598.Cal7507_1758	2.27e-39	159.0	COG2380@1|root,COG2380@2|Bacteria,1GDAS@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4421953_0	1340493.JNIF01000003_gene3597	2.95e-48	181.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
GDHHQS2_k127_4428305_8	234267.Acid_0305	7.24e-12	78.0	2E7Z1@1|root,332DD@2|Bacteria,3Y91V@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4428305_6	330214.NIDE1183	1.029e-44	167.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4428305_9	926569.ANT_25800	0.000182	49.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4428305_1	234267.Acid_7040	2.076e-255	803.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria	57723|Acidobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS2_k127_4428305_0	575540.Isop_3282	0.0	1165.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_4428305_7	575540.Isop_3282	4.854e-41	157.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_4428305_3	1396418.BATQ01000163_gene1998	1.583e-218	687.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
GDHHQS2_k127_4428305_2	1267535.KB906767_gene1540	2.624e-243	789.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4428305_4	1144275.COCOR_02127	1.443e-108	378.0	COG1470@1|root,COG1470@2|Bacteria,1R2QR@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4428305_5	1267535.KB906767_gene2230	1.735e-97	333.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4445912_3	1121272.KB903292_gene3909	0.0006046	44.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4D9WU@85008|Micromonosporales	201174|Actinobacteria	C	conserved protein containing a ferredoxin-like domain	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
GDHHQS2_k127_4445912_0	234267.Acid_5761	1.822e-56	206.0	COG1556@1|root,COG1556@2|Bacteria,3Y5T6@57723|Acidobacteria	57723|Acidobacteria	S	Pfam:DUF162	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
GDHHQS2_k127_4445912_2	1501391.LG35_09525	2.094e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,2FMT6@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4452466_1	1408433.JHXV01000041_gene3590	3.806e-10	68.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
GDHHQS2_k127_4452466_0	234267.Acid_2975	8.106e-152	496.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4454844_0	234267.Acid_7817	1.438e-243	764.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
GDHHQS2_k127_445546_3	138119.DSY0993	1.648e-47	179.0	COG1145@1|root,COG1145@2|Bacteria,1UIDU@1239|Firmicutes,25EIV@186801|Clostridia,267A7@186807|Peptococcaceae	186801|Clostridia	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_445546_0	1346791.M529_04545	8.215e-169	542.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2TTHW@28211|Alphaproteobacteria,2K02B@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator Superfamily	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
GDHHQS2_k127_445546_2	1340493.JNIF01000003_gene3710	5.595e-115	375.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS2_k127_445546_1	1340493.JNIF01000003_gene3711	2.157e-150	482.0	COG0836@1|root,COG0836@2|Bacteria,3Y2W2@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS2_k127_4471806_8	234267.Acid_7345	6.02e-09	57.0	COG0500@1|root,COG2226@2|Bacteria,3Y44I@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_4471806_2	1267535.KB906767_gene5225	1.428e-223	699.0	COG0673@1|root,COG0673@2|Bacteria,3Y7B1@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4471806_3	1340493.JNIF01000003_gene2958	4.759e-127	417.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria	57723|Acidobacteria	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS2_k127_4471806_6	1340493.JNIF01000003_gene2959	6.089e-77	267.0	COG1266@1|root,COG1266@2|Bacteria,3Y4ED@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_4471806_5	234267.Acid_7366	2.951e-87	295.0	2D61V@1|root,32TKB@2|Bacteria,3Y5CF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4471806_0	1340493.JNIF01000004_gene1083	8.72e-258	818.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4471806_1	886293.Sinac_6931	2.495e-235	735.0	COG4102@1|root,COG4102@2|Bacteria,2IXNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4471806_4	1449063.JMLS01000020_gene5213	1.347e-101	348.0	COG5476@1|root,COG5476@2|Bacteria,1UY0D@1239|Firmicutes,4HDB2@91061|Bacilli,26VYS@186822|Paenibacillaceae	91061|Bacilli	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
GDHHQS2_k127_4471806_7	452637.Oter_2672	2.344e-70	255.0	COG2271@1|root,COG2271@2|Bacteria,46UQA@74201|Verrucomicrobia,3K8MQ@414999|Opitutae	414999|Opitutae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4476901_0	1340493.JNIF01000003_gene2575	1.348e-273	874.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4476901_2	1267535.KB906767_gene4920	8.427e-12	71.0	COG1629@1|root,COG4771@2|Bacteria,3Y7CC@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4476901_1	639030.JHVA01000001_gene3949	2.045e-12	71.0	2E19M@1|root,2ZCDB@2|Bacteria,3Y4DH@57723|Acidobacteria,2JJ2T@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4477896_1	278963.ATWD01000001_gene1304	6.107e-06	49.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4477896_0	234267.Acid_2658	5.096e-141	458.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2
GDHHQS2_k127_448325_3	234267.Acid_7677	3e-19	87.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_448325_1	1267533.KB906736_gene1246	2.015e-183	608.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_448325_2	1210884.HG799466_gene12834	1.829e-43	180.0	COG0412@1|root,COG1073@1|root,COG3386@1|root,COG0412@2|Bacteria,COG1073@2|Bacteria,COG3386@2|Bacteria,2IWX0@203682|Planctomycetes	203682|Planctomycetes	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS2_k127_448325_0	234267.Acid_5309	4.562e-184	583.0	COG0686@1|root,COG0686@2|Bacteria,3Y3Y9@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS2_k127_448325_4	1267535.KB906767_gene3232	6.117e-19	92.0	COG3409@1|root,COG3409@2|Bacteria,3Y5JQ@57723|Acidobacteria	57723|Acidobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
GDHHQS2_k127_4485516_1	234267.Acid_3073	3.307e-57	201.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_4485516_0	1340493.JNIF01000004_gene1098	0.0	1254.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4491875_1	886293.Sinac_1877	9.34e-48	185.0	COG0412@1|root,COG0412@2|Bacteria,2IXM6@203682|Planctomycetes	203682|Planctomycetes	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GDHHQS2_k127_4491875_0	1340493.JNIF01000003_gene1862	4.439e-156	510.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_4492301_1	234267.Acid_3484	4.32e-312	975.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS2_k127_4492301_0	1267535.KB906767_gene7	0.0	1059.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_4492301_2	234267.Acid_2796	2.393e-141	458.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_4495012_1	1340493.JNIF01000003_gene3743	1.095e-64	225.0	COG1172@1|root,COG1172@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS2_k127_4495012_0	1340493.JNIF01000003_gene3744	5.24e-203	643.0	COG1129@1|root,COG1129@2|Bacteria,3Y3UY@57723|Acidobacteria	57723|Acidobacteria	P	ABC transporter	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10562	ko02010,map02010	M00212,M00215,M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.9	-	-	ABC_tran
GDHHQS2_k127_4508564_1	234267.Acid_3554	3.713e-63	225.0	COG2870@1|root,COG2870@2|Bacteria,3Y680@57723|Acidobacteria	57723|Acidobacteria	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS2_k127_4508564_0	234267.Acid_2237	3.39e-73	256.0	COG0279@1|root,COG0279@2|Bacteria,3Y7D7@57723|Acidobacteria	57723|Acidobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GDHHQS2_k127_4508564_2	234267.Acid_5312	1.871e-29	118.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS2_k127_4508564_3	1267535.KB906767_gene313	7.575e-11	62.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GDHHQS2_k127_4512828_0	234267.Acid_2226	3.36e-132	441.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_4512828_1	933801.Ahos_2224	6.441e-40	149.0	COG2080@1|root,arCOG01925@2157|Archaea,2XQC1@28889|Crenarchaeota	28889|Crenarchaeota	C	2Fe-2S -binding domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114	1.2.5.3,1.2.99.8	ko:K03518,ko:K18022	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R10324,R11168	RC00242,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_4513471_1	234267.Acid_4059	1.434e-57	206.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4513471_0	234267.Acid_4060	1.66e-187	595.0	COG4102@1|root,COG4102@2|Bacteria,3Y6RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4513471_2	1340493.JNIF01000003_gene1892	5.975e-15	79.0	COG1629@1|root,COG4771@2|Bacteria,3Y6MN@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4515440_1	1267535.KB906767_gene5488	1.328e-151	486.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria,2JHR5@204432|Acidobacteriia	204432|Acidobacteriia	E	GXGXG motif	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS2_k127_4515440_0	234267.Acid_3815	9.269e-223	709.0	COG0493@1|root,COG0493@2|Bacteria,3Y2JM@57723|Acidobacteria	57723|Acidobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS2_k127_4516132_1	234267.Acid_1043	3.028e-119	386.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_4516132_3	1123242.JH636434_gene5302	4.529e-76	281.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4516132_0	1267535.KB906767_gene1410	9.726e-178	564.0	COG0126@1|root,COG0126@2|Bacteria,3Y2T7@57723|Acidobacteria,2JI0Z@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS2_k127_4516132_2	478741.JAFS01000001_gene1646	9.659e-110	365.0	COG0624@1|root,COG0624@2|Bacteria,46SJS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_4530868_0	1340493.JNIF01000004_gene600	8.114e-292	915.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4530868_1	1340493.JNIF01000004_gene601	1.138e-150	490.0	COG0666@1|root,COG0666@2|Bacteria,3Y8C5@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
GDHHQS2_k127_4530868_5	1267535.KB906767_gene4277	6.462e-60	212.0	COG0789@1|root,COG0789@2|Bacteria,3Y5EZ@57723|Acidobacteria,2JN9T@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_4530868_2	234267.Acid_2600	1.706e-142	458.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4530868_3	234267.Acid_3771	1.556e-126	416.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4530868_4	1340493.JNIF01000003_gene3900	1.006e-69	252.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4530868_6	234267.Acid_3417	1.001e-16	83.0	2EQAC@1|root,33HWH@2|Bacteria,3Y5W6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4530868_8	639030.JHVA01000001_gene2618	6.434e-06	55.0	COG2382@1|root,COG2382@2|Bacteria,3Y5EH@57723|Acidobacteria,2JJUH@204432|Acidobacteriia	204432|Acidobacteriia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_4530868_7	1340493.JNIF01000004_gene755	2.57e-14	79.0	COG2382@1|root,COG2382@2|Bacteria,3Y5EH@57723|Acidobacteria	57723|Acidobacteria	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_4533090_0	1267535.KB906767_gene4978	7.841e-147	471.0	COG0495@1|root,COG0495@2|Bacteria,3Y37K@57723|Acidobacteria,2JIGF@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS2_k127_4533090_1	584708.Apau_1828	1.131e-78	273.0	COG4637@1|root,COG4637@2|Bacteria,3TCHW@508458|Synergistetes	508458|Synergistetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4533090_2	314230.DSM3645_12901	1.325e-25	112.0	2E0WE@1|root,32WDE@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
GDHHQS2_k127_453514_2	1267535.KB906767_gene3656	1.281e-28	123.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_453514_4	204669.Acid345_1452	1.431e-23	106.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_453514_3	1267535.KB906767_gene2038	3.384e-26	111.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
GDHHQS2_k127_453514_0	1267534.KB906761_gene1211	2.134e-61	228.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria,2JMQC@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_453514_1	760192.Halhy_5620	8.887e-35	140.0	COG0477@1|root,COG2814@2|Bacteria,4PNZI@976|Bacteroidetes	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4535997_0	234267.Acid_1167	4.852e-195	615.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_4535997_3	234267.Acid_1168	1.869e-33	131.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria	57723|Acidobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS2_k127_4535997_1	1123242.JH636434_gene5302	1.923e-103	353.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4535997_2	1340493.JNIF01000003_gene4593	5.441e-99	342.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS2_k127_4538259_1	1267535.KB906767_gene3045	3.256e-18	91.0	2FHZB@1|root,349S8@2|Bacteria,3Y8KS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4538259_2	234267.Acid_3671	6.429e-13	78.0	COG1506@1|root,COG1506@2|Bacteria,3Y6P1@57723|Acidobacteria	57723|Acidobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_4538259_0	926566.Terro_1174	2.701e-138	467.0	COG1629@1|root,COG4771@2|Bacteria,3Y2M5@57723|Acidobacteria,2JMJB@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_454102_13	1095750.HMPREF9970_0146	1.407e-16	79.0	COG3335@1|root,COG3335@2|Bacteria,1UQRR@1239|Firmicutes,24BSD@186801|Clostridia,1HW90@1164882|Lachnoanaerobaculum	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GDHHQS2_k127_454102_18	395965.Msil_1888	0.0008778	50.0	2F681@1|root,33YRY@2|Bacteria,1NXVF@1224|Proteobacteria,2UTPE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Effector protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M91
GDHHQS2_k127_454102_2	1340493.JNIF01000003_gene4759	4.801e-166	530.0	COG2355@1|root,COG2355@2|Bacteria,3Y3RS@57723|Acidobacteria	57723|Acidobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_454102_4	1340493.JNIF01000003_gene2187	8.356e-130	425.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_454102_3	234267.Acid_2231	5.667e-153	499.0	COG1473@1|root,COG1473@2|Bacteria	2|Bacteria	S	N-acetyldiaminopimelate deacetylase activity	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_454102_5	661478.OP10G_0528	5.421e-117	400.0	COG1028@1|root,COG1028@2|Bacteria	661478.OP10G_0528|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_454102_8	234267.Acid_3183	2.741e-93	308.0	COG2316@1|root,COG2316@2|Bacteria,3Y4GI@57723|Acidobacteria	57723|Acidobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_454102_7	234267.Acid_5589	2.677e-94	316.0	COG1622@1|root,COG1622@2|Bacteria,3Y4UA@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GDHHQS2_k127_454102_1	234267.Acid_5590	1.179e-268	841.0	COG0843@1|root,COG0843@2|Bacteria,3Y2NS@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_454102_11	234267.Acid_5591	5.344e-54	196.0	COG1845@1|root,COG1845@2|Bacteria,3Y2KJ@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS2_k127_454102_10	234267.Acid_5592	1.492e-73	252.0	COG1845@1|root,COG1845@2|Bacteria,3Y5GJ@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS2_k127_454102_6	1382359.JIAL01000001_gene2516	1.344e-107	355.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria,2JK6X@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
GDHHQS2_k127_454102_15	1380386.JIAW01000008_gene6067	3.032e-12	71.0	2EEUI@1|root,338N1@2|Bacteria,2IS84@201174|Actinobacteria,23DYR@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_454102_9	234267.Acid_1586	1.249e-76	262.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
GDHHQS2_k127_454102_0	1267535.KB906767_gene5100	0.0	1029.0	COG1166@1|root,COG1166@2|Bacteria,3Y449@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GDHHQS2_k127_454102_12	1262449.CP6013_3373	1.395e-18	94.0	COG1595@1|root,COG1595@2|Bacteria,1V95F@1239|Firmicutes,24M65@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_454102_16	1298863.AUEP01000003_gene2968	2.123e-05	55.0	2C7PU@1|root,33JNE@2|Bacteria,2GZ9R@201174|Actinobacteria	201174|Actinobacteria	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
GDHHQS2_k127_4556151_4	1340493.JNIF01000003_gene2259	6.244e-71	244.0	COG2230@1|root,COG2230@2|Bacteria,3Y9AA@57723|Acidobacteria	57723|Acidobacteria	M	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_4556151_1	1267535.KB906767_gene247	3.1e-136	443.0	COG1820@1|root,COG1820@2|Bacteria,3Y3NQ@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_4556151_0	1267535.KB906767_gene943	5.792e-214	670.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	2|Bacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4556151_2	1267535.KB906767_gene3453	2.38e-81	285.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4556151_5	1380347.JNII01000006_gene1801	3.526e-34	136.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4EVV5@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_4556866_9	234267.Acid_6261	4.554e-09	70.0	COG3391@1|root,COG3391@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_4556866_10	1340493.JNIF01000003_gene4693	0.0003666	54.0	COG0652@1|root,COG5563@1|root,COG0652@2|Bacteria,COG5563@2|Bacteria,3Y8DZ@57723|Acidobacteria	57723|Acidobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS2_k127_4556866_3	1340493.JNIF01000003_gene2778	1.036e-83	286.0	COG1295@1|root,COG1295@2|Bacteria,3Y4P8@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ribonuclease	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS2_k127_4556866_4	1340493.JNIF01000003_gene2777	9.742e-80	286.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GDHHQS2_k127_4556866_6	1121403.AUCV01000002_gene474	2.225e-41	157.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
GDHHQS2_k127_4556866_0	933262.AXAM01000026_gene3073	2.492e-181	581.0	COG1672@1|root,COG1672@2|Bacteria,1R4NN@1224|Proteobacteria,42NMV@68525|delta/epsilon subdivisions,2WM2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,AAA_35
GDHHQS2_k127_4556866_8	243365.CV_3182	4.436e-31	129.0	COG5553@1|root,COG5553@2|Bacteria,1NXEP@1224|Proteobacteria	1224|Proteobacteria	C	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
GDHHQS2_k127_4556866_1	1122605.KB893649_gene3749	5.725e-161	522.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	2|Bacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4556866_5	1396141.BATP01000045_gene1809	1.482e-59	220.0	2DVY4@1|root,33XNN@2|Bacteria,46VB3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4556866_7	1122176.KB903531_gene2954	1.979e-32	145.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,PrcB_C,Prenyltrans,SLH,SQHop_cyclase_C
GDHHQS2_k127_4556866_2	278963.ATWD01000003_gene34	4.887e-118	400.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4558117_2	234267.Acid_7758	8.733e-122	410.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4558117_7	1340493.JNIF01000003_gene4189	7.979e-39	149.0	COG1430@1|root,COG1430@2|Bacteria,3Y5J5@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS2_k127_4558117_5	234267.Acid_7756	6.759e-52	196.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_7756|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4558117_9	234267.Acid_7755	2.62e-15	78.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
GDHHQS2_k127_4558117_1	234267.Acid_7754	2.996e-129	430.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS2_k127_4558117_4	234267.Acid_7753	9.549e-64	229.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS2_k127_4558117_0	234267.Acid_7752	5.862e-158	511.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
GDHHQS2_k127_4558117_3	234267.Acid_7751	7.247e-93	322.0	COG4655@1|root,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
GDHHQS2_k127_4558117_8	234267.Acid_7750	3.703e-32	132.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS2_k127_4570237_1	234267.Acid_0381	3.253e-39	149.0	COG4577@1|root,COG4577@2|Bacteria	234267.Acid_0381|-	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4570237_0	1295642.H839_02161	7.99e-134	444.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli,1WFP5@129337|Geobacillus	91061|Bacilli	C	Aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_4574925_1	1267535.KB906767_gene1184	4.511e-47	170.0	COG0247@1|root,COG0247@2|Bacteria,3Y3K8@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GDHHQS2_k127_4574925_0	234267.Acid_7674	1.864e-155	510.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria	57723|Acidobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GDHHQS2_k127_4575510_5	391625.PPSIR1_07173	1.275e-11	70.0	COG1881@1|root,COG1881@2|Bacteria	2|Bacteria	S	positive regulation of acetylcholine metabolic process	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	CBM_6,GSDH,PBP,Polyketide_cyc2,YHYH,fn3
GDHHQS2_k127_4575510_2	1267535.KB906767_gene5422	3.554e-114	385.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,3Y4NJ@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_4575510_3	1340493.JNIF01000003_gene2280	1.423e-83	302.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4575510_4	234267.Acid_2091	4.268e-83	291.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4575510_1	1340493.JNIF01000003_gene3752	7.255e-126	408.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	SGL
GDHHQS2_k127_4575510_0	335543.Sfum_1617	9.439e-145	473.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_4580719_1	234267.Acid_1024	2.053e-149	479.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,DUF2048,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_4580719_2	234267.Acid_1025	4.517e-110	368.0	COG0738@1|root,COG0738@2|Bacteria,3Y6YP@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4580719_0	234267.Acid_6424	6.121e-214	691.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria	57723|Acidobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS2_k127_4580719_3	886293.Sinac_1155	7.058e-28	114.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
GDHHQS2_k127_4606989_0	1340493.JNIF01000004_gene88	3.621e-280	895.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_4607572_0	452637.Oter_1726	2.689e-49	182.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_4607572_1	702437.HMPREF9432_01472	1.567e-25	113.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4H4K0@909932|Negativicutes	909932|Negativicutes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS2_k127_4607572_3	794903.OPIT5_26490	1.89e-17	87.0	2C4M3@1|root,2ZD1R@2|Bacteria,46WTA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_2
GDHHQS2_k127_4607572_2	404589.Anae109_3322	1.213e-23	102.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,433TY@68525|delta/epsilon subdivisions,2WWM0@28221|Deltaproteobacteria,2YVY5@29|Myxococcales	28221|Deltaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
GDHHQS2_k127_4609625_0	886293.Sinac_2713	4.261e-87	300.0	COG3828@1|root,COG3828@2|Bacteria,2IYPM@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS2_k127_461762_3	1128398.Curi_c07990	6.912e-09	59.0	COG2337@1|root,COG2337@2|Bacteria,1V6CM@1239|Firmicutes,24PG5@186801|Clostridia,26C2C@186813|unclassified Clostridiales	186801|Clostridia	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_461762_2	111780.Sta7437_4347	1.402e-16	81.0	COG2337@1|root,COG2337@2|Bacteria,1G7JA@1117|Cyanobacteria,3VKAN@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM PemK-like protein	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_461762_1	575540.Isop_2410	3.727e-77	272.0	COG1961@1|root,COG1961@2|Bacteria,2IXU9@203682|Planctomycetes	203682|Planctomycetes	L	DNA invertase Pin	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_461762_5	1279017.AQYJ01000026_gene22	0.0009726	42.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_461762_0	1038860.AXAP01000008_gene5969	3.195e-230	729.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2UQJ2@28211|Alphaproteobacteria,3K2BQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
GDHHQS2_k127_461762_4	1151122.AQYD01000007_gene638	4.534e-07	57.0	COG3170@1|root,COG3170@2|Bacteria,2IANU@201174|Actinobacteria	201174|Actinobacteria	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
GDHHQS2_k127_4620088_1	555079.Toce_0685	1.146e-71	250.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_4620088_0	478741.JAFS01000001_gene1889	2.37e-179	570.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,37G5G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS2_k127_4624866_1	1121481.AUAS01000005_gene1845	1.331e-76	268.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47ND1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4624866_0	357808.RoseRS_2562	8.997e-142	460.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS2_k127_4626415_2	234267.Acid_6602	1.706e-138	447.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,3Y2QH@57723|Acidobacteria	57723|Acidobacteria	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
GDHHQS2_k127_4626415_0	1340493.JNIF01000003_gene2872	5.275e-257	810.0	COG1449@1|root,COG1449@2|Bacteria,3Y36M@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
GDHHQS2_k127_4626415_3	449447.MAE_62230	1.085e-52	193.0	COG4636@1|root,COG4636@2|Bacteria,1G0G0@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_4626415_1	1340493.JNIF01000003_gene3565	3.058e-195	637.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_463168_0	926560.KE387027_gene713	4.159e-120	392.0	COG2303@1|root,COG2303@2|Bacteria,1WMTM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_463168_1	795666.MW7_0585	5.839e-86	294.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4644189_2	1340493.JNIF01000003_gene3561	2.731e-05	51.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4644189_0	234267.Acid_3331	2.29e-155	507.0	COG0673@1|root,COG0673@2|Bacteria,3Y2KV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4644189_1	234267.Acid_7505	4.315e-56	207.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367,LolA,LolA_like
GDHHQS2_k127_4645704_0	1340493.JNIF01000003_gene1861	2.555e-162	532.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_4645704_1	204669.Acid345_4244	1.223e-21	104.0	COG1595@1|root,COG1595@2|Bacteria,3Y58Z@57723|Acidobacteria,2JN7R@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
GDHHQS2_k127_4645704_2	204669.Acid345_4245	1.06e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,3Y85C@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4666315_0	1379270.AUXF01000001_gene1899	2.711e-100	338.0	COG0251@1|root,COG3391@1|root,COG0251@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP,VCBS
GDHHQS2_k127_4666315_2	204669.Acid345_1386	3.914e-44	168.0	2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4666315_1	1379698.RBG1_1C00001G0452	2.537e-96	317.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
GDHHQS2_k127_4671881_0	1128421.JAGA01000003_gene2870	5.176e-163	526.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
GDHHQS2_k127_4671881_2	234267.Acid_0489	1.466e-91	305.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS2_k127_4671881_1	861299.J421_2233	1.498e-130	426.0	COG4993@1|root,COG4993@2|Bacteria,1ZUDV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_4678369_1	690850.Desaf_0734	8.758e-52	192.0	COG0438@1|root,COG0438@2|Bacteria,1PERD@1224|Proteobacteria,42VK8@68525|delta/epsilon subdivisions,2WSBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4678369_0	697282.Mettu_3895	5.916e-104	347.0	COG1215@1|root,COG1215@2|Bacteria,1R4ZM@1224|Proteobacteria,1S1EG@1236|Gammaproteobacteria,1XFAH@135618|Methylococcales	135618|Methylococcales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_4685179_0	234267.Acid_1502	1.494e-153	501.0	COG0815@1|root,COG0815@2|Bacteria,3Y4FZ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GDHHQS2_k127_4685179_2	234267.Acid_1501	4.669e-136	440.0	COG0320@1|root,COG0320@2|Bacteria,3Y6DY@57723|Acidobacteria	57723|Acidobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS2_k127_4685179_4	1340493.JNIF01000003_gene4333	8.376e-24	110.0	COG3087@1|root,COG3087@2|Bacteria,3Y4WI@57723|Acidobacteria	57723|Acidobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GDHHQS2_k127_4685179_3	153721.MYP_2281	5.497e-93	323.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4685179_1	401053.AciPR4_1573	7.664e-137	477.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4685179_5	99598.Cal7507_2948	1.504e-11	66.0	COG3744@1|root,COG3744@2|Bacteria,1G9VS@1117|Cyanobacteria,1HQ0Y@1161|Nostocales	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_4692064_1	1169161.KB897727_gene979	4.563e-38	164.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
GDHHQS2_k127_4692064_0	234267.Acid_6696	9.859e-94	312.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GX@57723|Acidobacteria	57723|Acidobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4692064_3	1267535.KB906767_gene1696	3.459e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,3Y933@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_4692064_2	1267535.KB906767_gene1697	1.12e-22	109.0	2E98K@1|root,333GZ@2|Bacteria,3Y55V@57723|Acidobacteria,2JK78@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4693898_5	204669.Acid345_4234	2.687e-05	54.0	COG0745@1|root,COG0823@1|root,COG0745@2|Bacteria,COG0823@2|Bacteria,3Y7SS@57723|Acidobacteria,2JMXC@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_4693898_4	379066.GAU_0974	2.656e-05	54.0	29KMP@1|root,307IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
GDHHQS2_k127_4693898_6	1205680.CAKO01000017_gene27	8.172e-05	47.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2UFXF@28211|Alphaproteobacteria,2JTWC@204441|Rhodospirillales	204441|Rhodospirillales	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS2_k127_4693898_3	234267.Acid_3819	3.119e-52	201.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4693898_2	1340493.JNIF01000003_gene2146	2.464e-63	224.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_4693898_1	1449346.JQMO01000001_gene7043	4.193e-75	286.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
GDHHQS2_k127_4693898_0	234267.Acid_1599	9.973e-150	515.0	COG0793@1|root,COG0793@2|Bacteria,3Y6R0@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_4699232_2	1380394.JADL01000004_gene5747	5.811e-10	60.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd2	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS2_k127_4699232_1	443598.AUFA01000028_gene7138	1.595e-83	278.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS2_k127_4699232_0	1380394.JADL01000009_gene3376	1.474e-160	514.0	COG0605@1|root,COG0607@1|root,COG0605@2|Bacteria,COG0607@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Sod_Fe_C
GDHHQS2_k127_470198_4	1267535.KB906767_gene1486	3.94e-12	66.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS2_k127_470198_2	234267.Acid_1221	5.202e-19	90.0	COG3027@1|root,COG3027@2|Bacteria,3Y8Q5@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein ZapA	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GDHHQS2_k127_470198_0	234267.Acid_5816	1.395e-267	841.0	COG0339@1|root,COG0339@2|Bacteria,3Y3U9@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase	-	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS2_k127_470198_1	234267.Acid_0128	1.085e-76	263.0	COG0634@1|root,COG0634@2|Bacteria,3Y2FD@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_4703317_1	574376.BAMA_22255	2.948e-74	252.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS2_k127_4703317_2	1267535.KB906767_gene2141	1.909e-33	130.0	2CBEB@1|root,32STF@2|Bacteria,3Y5AC@57723|Acidobacteria,2JJNZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4703317_0	1267535.KB906767_gene676	6.617e-80	270.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_470454_4	1219035.NT2_01_05540	2.195e-74	264.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,2KCTY@204457|Sphingomonadales	204457|Sphingomonadales	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6,4.2.1.8,5.1.2.2	ko:K01684,ko:K01781,ko:K08323	ko00040,ko00052,ko00627,ko01100,ko01120,map00040,map00052,map00627,map01100,map01120	M00061,M00552	R03033,R03791,R04161,R05606	RC00543,RC00998	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_470454_2	886293.Sinac_4982	8.489e-99	328.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_470454_3	1346791.M529_07430	3.371e-92	317.0	COG3836@1|root,COG3836@2|Bacteria,1R9U6@1224|Proteobacteria,2TSTY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_470454_0	1340493.JNIF01000003_gene3433	4.149e-176	581.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_470454_1	1340493.JNIF01000003_gene4135	1.612e-161	526.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_470454_5	652103.Rpdx1_3915	8.536e-10	63.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JU23@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4716660_0	1340493.JNIF01000003_gene4144	8.62e-112	378.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4716824_3	1045855.DSC_03395	1.664e-88	298.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_4716824_7	1122604.JONR01000049_gene752	3.617e-05	53.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,1S7QH@1236|Gammaproteobacteria,1X5S6@135614|Xanthomonadales	135614|Xanthomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
GDHHQS2_k127_4716824_4	1267535.KB906767_gene3788	2.344e-64	225.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria,2JJ1A@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS2_k127_4716824_2	1267535.KB906767_gene3789	5.483e-93	309.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria,2JID7@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_4716824_0	234267.Acid_0307	1.979e-165	532.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria	57723|Acidobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GDHHQS2_k127_4716824_5	234267.Acid_0308	5.274e-52	189.0	COG3118@1|root,COG3118@2|Bacteria,3Y53D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS2_k127_4716824_1	1267535.KB906767_gene4528	7.657e-131	425.0	COG0078@1|root,COG0078@2|Bacteria,3Y4R3@57723|Acidobacteria,2JP1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS2_k127_4716824_6	234267.Acid_2504	1.524e-18	87.0	COG0165@1|root,COG0165@2|Bacteria,3Y36Y@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS2_k127_4718959_2	1340493.JNIF01000004_gene177	8.07e-26	121.0	COG1657@1|root,COG3391@1|root,COG1657@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14647,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	-
GDHHQS2_k127_4718959_1	1267534.KB906754_gene3764	1.003e-53	201.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GDHHQS2_k127_4718959_0	1267534.KB906754_gene3763	7.446e-271	862.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4727936_2	1121127.JAFA01000076_gene6471	3.113e-16	92.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2VTE1@28216|Betaproteobacteria,1K3TA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
GDHHQS2_k127_4727936_1	566466.NOR53_2804	2.255e-188	599.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J8JK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_4727936_0	1340493.JNIF01000004_gene277	2.195e-245	765.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4728601_4	270374.MELB17_08416	5.765e-08	59.0	COG5464@1|root,COG5464@2|Bacteria,1PXZD@1224|Proteobacteria,1RQBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GDHHQS2_k127_4728601_3	1227499.C493_09383	1.155e-60	237.0	2DZ85@1|root,2N5HN@2157|Archaea,2Y0TM@28890|Euryarchaeota,23Y9H@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
GDHHQS2_k127_4728601_0	204669.Acid345_3921	1.237e-191	615.0	COG0146@1|root,COG0146@2|Bacteria,3Y6W2@57723|Acidobacteria,2JKCE@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
GDHHQS2_k127_4728601_2	234267.Acid_5885	2.283e-64	232.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
GDHHQS2_k127_4728601_1	1382306.JNIM01000001_gene853	9.877e-87	302.0	COG1304@1|root,COG1304@2|Bacteria,2G84G@200795|Chloroflexi	200795|Chloroflexi	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
GDHHQS2_k127_4728922_4	1340493.JNIF01000003_gene1755	0.0009174	44.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4728922_1	330214.NIDE1190	7.841e-50	189.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_4728922_2	1267535.KB906767_gene209	8.548e-49	185.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GDHHQS2_k127_4728922_3	479434.Sthe_3302	1.405e-28	126.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GDHHQS2_k127_4728922_0	234267.Acid_2734	1.464e-212	697.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_4733694_2	1340493.JNIF01000003_gene2519	2.31e-77	269.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_4733694_1	234267.Acid_5196	2.281e-127	412.0	COG0500@1|root,COG2226@2|Bacteria,3Y4B3@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_4733694_0	1267535.KB906767_gene3806	0.0	1004.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS2_k127_4733694_3	234267.Acid_6223	1.028e-60	213.0	COG0054@1|root,COG0054@2|Bacteria,3Y3RR@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS2_k127_4733694_4	234267.Acid_6222	2.629e-42	160.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria	57723|Acidobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS2_k127_4737006_0	234267.Acid_3977	4.392e-153	510.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4738659_11	1267535.KB906767_gene2140	2.208e-71	244.0	COG0531@1|root,COG0531@2|Bacteria,3Y3SZ@57723|Acidobacteria,2JI7T@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_4738659_16	1340493.JNIF01000003_gene4296	1.039e-07	62.0	2DZRA@1|root,32VGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_4738659_17	1340493.JNIF01000003_gene4296	1.135e-07	56.0	2DZRA@1|root,32VGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_4738659_15	1385517.N800_00445	6.724e-21	108.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1PH1W@1224|Proteobacteria,1RRYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,P_proprotein,Reprolysin_3,Reprolysin_4
GDHHQS2_k127_4738659_13	1340493.JNIF01000003_gene2911	5.241e-31	141.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_4738659_4	1210884.HG799463_gene10143	7.869e-152	488.0	COG0673@1|root,COG0673@2|Bacteria,2J27T@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4738659_5	886293.Sinac_6663	8.158e-151	482.0	COG1082@1|root,COG1082@2|Bacteria,2IY42@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_4738659_14	1385517.N800_00445	1.286e-24	122.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1PH1W@1224|Proteobacteria,1RRYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,P_proprotein,Reprolysin_3,Reprolysin_4
GDHHQS2_k127_4738659_10	1444711.CCJF01000005_gene546	5.975e-114	406.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
GDHHQS2_k127_4738659_9	234267.Acid_7361	2.449e-114	385.0	COG1807@1|root,COG1807@2|Bacteria,3Y6PY@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4738659_6	234267.Acid_7362	1.634e-136	439.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
GDHHQS2_k127_4738659_3	378806.STAUR_8391	1.158e-164	550.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3TP@28221|Deltaproteobacteria,2YX2Z@29|Myxococcales	28221|Deltaproteobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS2_k127_4738659_8	234267.Acid_7265	4.751e-116	381.0	COG0564@1|root,COG0564@2|Bacteria,3Y3G8@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_4738659_7	234267.Acid_7266	3.889e-128	416.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
GDHHQS2_k127_4738659_12	1267535.KB906767_gene5516	1.464e-70	255.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
GDHHQS2_k127_4738659_1	1267535.KB906767_gene4734	2.616e-204	644.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS2_k127_4738659_2	234267.Acid_3250	6.351e-168	537.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	megL	-	2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8	ko:K01739,ko:K01740,ko:K01760,ko:K01761,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01287,R01288,R02408,R02508,R03217,R03260,R04770,R04859,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02821,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_4738659_0	234267.Acid_2648	8.056e-215	676.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.6.3.38	ko:K07214,ko:K09689	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101	-	-	Esterase,SGL
GDHHQS2_k127_4739124_0	234267.Acid_6871	1.71e-218	698.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4739124_2	234267.Acid_2730	3.506e-77	273.0	28PTH@1|root,2ZCER@2|Bacteria,3Y860@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4739124_1	234267.Acid_2729	2.786e-119	395.0	28K3C@1|root,2Z9SH@2|Bacteria,3Y7UF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4749569_3	1122223.KB890701_gene2301	0.0002048	53.0	COG2010@1|root,COG2010@2|Bacteria,1WJ3M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_4749569_0	420662.Mpe_A3660	5.338e-144	474.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VM62@28216|Betaproteobacteria,1KIUI@119065|unclassified Burkholderiales	1224|Proteobacteria	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.2.8,1.1.5.11,1.1.5.2,1.1.9.1	ko:K00114,ko:K00117,ko:K17760,ko:K20937	ko00010,ko00030,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R06620	RC00066,RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_4749569_1	1267535.KB906767_gene3329	1.31e-103	345.0	COG1533@1|root,COG1533@2|Bacteria,3Y2S5@57723|Acidobacteria,2JIC8@204432|Acidobacteriia	204432|Acidobacteriia	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_4749569_2	234267.Acid_4195	2.08e-20	94.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,3Y6CI@57723|Acidobacteria	57723|Acidobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_4750313_11	595460.RRSWK_06596	1.648e-19	89.0	COG2960@1|root,COG2960@2|Bacteria,2J2BT@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4750313_0	756272.Plabr_3745	3.491e-212	685.0	COG1020@1|root,COG1020@2|Bacteria,2J2QU@203682|Planctomycetes	203682|Planctomycetes	Q	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4750313_2	889378.Spiaf_0362	6.273e-119	424.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,2J6U2@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Reg_prop,Response_reg,dCache_1
GDHHQS2_k127_4750313_1	234267.Acid_2416	3.131e-173	557.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
GDHHQS2_k127_4750313_7	234267.Acid_6307	4.218e-73	251.0	COG0122@1|root,COG0122@2|Bacteria,3Y7N6@57723|Acidobacteria	57723|Acidobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS2_k127_4750313_12	1347086.CCBA010000012_gene2030	3.248e-07	52.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4750313_5	1340493.JNIF01000004_gene332	6.128e-93	312.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS2_k127_4750313_9	234267.Acid_6375	5.813e-50	184.0	COG0352@1|root,COG0352@2|Bacteria,3Y53Y@57723|Acidobacteria	57723|Acidobacteria	H	PFAM thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS2_k127_4750313_4	234267.Acid_6374	1.306e-95	316.0	COG2191@1|root,COG2191@2|Bacteria,3Y43J@57723|Acidobacteria	57723|Acidobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
GDHHQS2_k127_4750313_3	1340493.JNIF01000003_gene3601	8.652e-119	396.0	COG3842@1|root,COG3842@2|Bacteria,3Y4VR@57723|Acidobacteria	57723|Acidobacteria	E	PFAM ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
GDHHQS2_k127_4750313_6	1267535.KB906767_gene4846	1.732e-83	282.0	COG4149@1|root,COG4149@2|Bacteria,3Y4EA@57723|Acidobacteria,2JJ3Z@204432|Acidobacteriia	204432|Acidobacteriia	P	Molybdate ABC transporter	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
GDHHQS2_k127_4750313_8	1340493.JNIF01000003_gene4796	1.036e-57	217.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HDOD,Response_reg
GDHHQS2_k127_4750313_10	1519464.HY22_04135	5.94e-21	95.0	COG1309@1|root,COG1309@2|Bacteria,1FFPT@1090|Chlorobi	1090|Chlorobi	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GDHHQS2_k127_4753860_0	268407.PWYN_17820	2.033e-23	106.0	COG0500@1|root,COG2226@2|Bacteria,1V3HT@1239|Firmicutes,4HHUM@91061|Bacilli,26SSS@186822|Paenibacillaceae	91061|Bacilli	Q	(SAM)-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_4753860_1	56110.Oscil6304_5681	2.737e-15	90.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG3391@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G2N0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF4347,HemolysinCabind,Laminin_G_3,SBP_bac_3,VCBS
GDHHQS2_k127_475413_1	1340493.JNIF01000003_gene2186	6.718e-80	276.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
GDHHQS2_k127_475413_0	234267.Acid_2269	5.027e-144	484.0	COG3391@1|root,COG5555@1|root,COG3391@2|Bacteria,COG5555@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Metallophos
GDHHQS2_k127_4755445_4	234267.Acid_4323	4.936e-17	93.0	COG4219@1|root,COG4219@2|Bacteria,3Y5JT@57723|Acidobacteria	57723|Acidobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
GDHHQS2_k127_4755445_3	1245469.S58_42370	2.604e-35	139.0	COG3682@1|root,COG3682@2|Bacteria,1RFCA@1224|Proteobacteria,2U5GV@28211|Alphaproteobacteria,3JY0T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS2_k127_4755445_2	101510.RHA1_ro02599	6.222e-97	326.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FUVW@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS2_k127_4755445_1	234267.Acid_2815	5.523e-99	336.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_4755445_0	234267.Acid_6430	1.828e-223	705.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria	57723|Acidobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS2_k127_4755445_5	234267.Acid_7350	1.108e-08	62.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_4759467_0	234267.Acid_5413	3.096e-259	814.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y6AS@57723|Acidobacteria	57723|Acidobacteria	CG	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_4759467_2	1299327.I546_5559	1.887e-28	117.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32,LZ_Tnp_IS481
GDHHQS2_k127_4759467_1	1299327.I546_5558	1.857e-41	158.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,23B0M@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GDHHQS2_k127_4766883_0	1267535.KB906767_gene942	6.626e-103	359.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4766883_1	655815.ZPR_1048	2.758e-09	69.0	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes,1HY3I@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
GDHHQS2_k127_4770362_1	1340493.JNIF01000003_gene3565	2.041e-103	347.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4770362_0	682795.AciX8_3594	3.334e-113	382.0	COG1629@1|root,COG4771@2|Bacteria,3Y461@57723|Acidobacteria,2JHPM@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4772279_5	688245.CtCNB1_3349	2.17e-47	175.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9RE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4772279_2	596154.Alide2_3931	2.021e-83	287.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4772279_0	318996.AXAZ01000082_gene3071	3.06e-129	423.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JW3J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_4772279_1	357808.RoseRS_3083	1.027e-107	374.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_4772279_3	1713.JOFV01000003_gene1506	1.12e-66	241.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4F1N6@85016|Cellulomonadaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_4772279_4	1195236.CTER_1193	3.061e-59	218.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,247Z1@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_4773334_3	1205680.CAKO01000035_gene321	3.428e-30	124.0	COG5529@1|root,COG5529@2|Bacteria,1NN87@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4773334_1	1340493.JNIF01000003_gene2296	4.705e-143	465.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	ko:K18106	ko00040,ko01100,map00040,map01100	M00630	R07676,R10565	RC00108	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4773334_0	1340493.JNIF01000003_gene2295	4.38e-191	606.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS2_k127_4773334_2	234267.Acid_1594	1.666e-43	162.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GDHHQS2_k127_4773334_5	234267.Acid_1595	2.132e-08	58.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_4776512_9	234267.Acid_4321	3.208e-21	100.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_4776512_0	573370.DMR_38040	1.197e-199	651.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_4776512_11	489825.LYNGBM3L_46260	6.874e-15	83.0	2DNGM@1|root,32XE4@2|Bacteria,1G88Z@1117|Cyanobacteria,1HH8A@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4776512_12	234267.Acid_4740	7.142e-14	76.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_4740|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4776512_8	1160718.SU9_04076	1.04e-22	113.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K21256	ko01059,ko01130,map01059,map01130	M00833,M00834	R11414	RC01363	ko00000,ko00001,ko00002	-	-	-	Trp_halogenase
GDHHQS2_k127_4776512_10	391625.PPSIR1_26933	5.836e-20	94.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS2_k127_4776512_3	204669.Acid345_3942	1.079e-85	291.0	COG4117@1|root,COG4117@2|Bacteria,3Y4KG@57723|Acidobacteria,2JJC0@204432|Acidobacteriia	204432|Acidobacteriia	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GDHHQS2_k127_4776512_2	1267533.KB906735_gene4583	5.669e-89	324.0	COG2041@1|root,COG2041@2|Bacteria,3Y3AI@57723|Acidobacteria,2JHW2@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_4776512_7	929562.Emtol_0791	9.901e-30	135.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS2_k127_4776512_5	1267533.KB906735_gene4583	1.939e-74	267.0	COG2041@1|root,COG2041@2|Bacteria,3Y3AI@57723|Acidobacteria,2JHW2@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_4776512_4	204669.Acid345_3942	1.439e-77	265.0	COG4117@1|root,COG4117@2|Bacteria,3Y4KG@57723|Acidobacteria,2JJC0@204432|Acidobacteriia	204432|Acidobacteriia	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GDHHQS2_k127_4776512_1	1267535.KB906767_gene4901	7.642e-175	553.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_4776512_6	1122138.AQUZ01000003_gene642	5.257e-72	265.0	COG4188@1|root,COG4188@2|Bacteria,2I3KQ@201174|Actinobacteria,4DN0K@85009|Propionibacteriales	201174|Actinobacteria	O	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Chlorophyllase2
GDHHQS2_k127_4776512_13	671143.DAMO_0170	0.0003276	44.0	COG3391@1|root,COG3391@2|Bacteria,2NQ7V@2323|unclassified Bacteria	2|Bacteria	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,Phosphoesterase
GDHHQS2_k127_4777409_2	1210884.HG799464_gene10536	1.932e-100	342.0	COG1453@1|root,COG1453@2|Bacteria,2IZF3@203682|Planctomycetes	203682|Planctomycetes	S	aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_4777409_0	864051.BurJ1DRAFT_2775	1.573e-145	473.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2WEME@28216|Betaproteobacteria,1KN2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_4777409_1	861299.J421_1106	4.73e-128	422.0	COG2010@1|root,COG2010@2|Bacteria,1ZT07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,HupE_UreJ_2
GDHHQS2_k127_4778640_4	1123073.KB899241_gene2586	8.762e-43	181.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
GDHHQS2_k127_4778640_5	234267.Acid_6124	6.067e-18	91.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,PRiA4_ORF3
GDHHQS2_k127_4778640_8	1133850.SHJG_2428	0.0001671	51.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
GDHHQS2_k127_4778640_6	1123321.KB905813_gene959	4.504e-17	95.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
GDHHQS2_k127_4778640_3	1441629.PCH70_40260	2.385e-80	280.0	COG1633@1|root,COG1633@2|Bacteria,1QW2P@1224|Proteobacteria,1S4MR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ferritin-like	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin-like,SnoaL_2
GDHHQS2_k127_4778640_0	215803.DB30_0658	3.261e-178	580.0	2DBN3@1|root,2ZA1Q@2|Bacteria,1PXHC@1224|Proteobacteria,438NW@68525|delta/epsilon subdivisions,2X3WR@28221|Deltaproteobacteria,2YXD5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4778640_2	234267.Acid_6335	6.606e-118	391.0	COG2706@1|root,COG2706@2|Bacteria,3Y4KD@57723|Acidobacteria	57723|Acidobacteria	G	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
GDHHQS2_k127_4778640_1	1288963.ADIS_3302	7.458e-135	441.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,47VT1@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_4778640_7	1123240.ATVO01000005_gene1951	7.863e-09	62.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_4782938_0	595460.RRSWK_00612	9.941e-164	525.0	COG0654@1|root,COG2755@1|root,COG0654@2|Bacteria,COG2755@2|Bacteria,2J0Y1@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_4782938_1	240016.ABIZ01000001_gene4842	2.235e-110	366.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_4782938_3	1227457.C451_14600	4.004e-43	169.0	COG0115@1|root,arCOG02297@2157|Archaea,2XSUC@28890|Euryarchaeota,23RWU@183963|Halobacteria	183963|Halobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	pabC	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_4782938_2	1089553.Tph_c20550	2.559e-98	333.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FM5@68295|Thermoanaerobacterales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
GDHHQS2_k127_4790370_11	1267535.KB906767_gene457	6.871e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,3Y7U6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4790370_0	234267.Acid_3111	0.0	1341.0	COG1629@1|root,COG4771@2|Bacteria,3Y6MN@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4790370_8	1267535.KB906767_gene4507	6.214e-60	210.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria,2JJGG@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS2_k127_4790370_9	1267535.KB906767_gene4506	1.297e-55	203.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria,2JJ7P@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS2_k127_4790370_5	653733.Selin_1758	2.539e-84	288.0	COG0052@1|root,COG0052@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS2_k127_4790370_4	234267.Acid_0905	6.799e-92	305.0	COG0264@1|root,COG0264@2|Bacteria,3Y3BT@57723|Acidobacteria	57723|Acidobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS2_k127_4790370_3	1267535.KB906767_gene4503	1.011e-109	359.0	COG0528@1|root,COG0528@2|Bacteria,3Y2FI@57723|Acidobacteria,2JISS@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_4790370_7	234267.Acid_0903	8.608e-79	267.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS2_k127_4790370_2	234267.Acid_0468	1.247e-122	404.0	COG1609@1|root,COG1609@2|Bacteria,3Y44C@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_4790370_1	1267535.KB906767_gene3483	0.0	1108.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4790370_6	234267.Acid_0319	9.454e-80	274.0	COG0705@1|root,COG0705@2|Bacteria,3Y4GU@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
GDHHQS2_k127_4790370_10	670487.Ocepr_1363	9.083e-22	101.0	COG0010@1|root,COG0010@2|Bacteria,1WI2B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS2_k127_4795515_0	234267.Acid_7323	7.794e-212	694.0	COG5479@1|root,COG5492@1|root,COG5479@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K11045	-	-	-	-	ko00000,ko02042	-	-	-	Big_2,CAMP_factor,CHB_HEX_C_1,LGFP,SLH
GDHHQS2_k127_4795515_3	696747.NIES39_C02300	7.487e-20	100.0	COG5464@1|root,COG5464@2|Bacteria,1FZUW@1117|Cyanobacteria,1H72A@1150|Oscillatoriales	1117|Cyanobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GDHHQS2_k127_4795515_2	1267534.KB906757_gene845	2.793e-95	323.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
GDHHQS2_k127_4795515_1	1267535.KB906767_gene951	1.262e-132	427.0	COG1262@1|root,COG2010@1|root,COG1262@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase,PSCyt1
GDHHQS2_k127_4796645_0	401053.AciPR4_1573	1.291e-136	457.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria,2JKVQ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4796645_1	234267.Acid_3912	4.692e-90	306.0	COG0545@1|root,COG0545@2|Bacteria,3Y5EV@57723|Acidobacteria	57723|Acidobacteria	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
GDHHQS2_k127_4796645_2	1340493.JNIF01000004_gene779	1.134e-31	130.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_4796856_0	1123057.P872_08485	7.801e-129	429.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47MUU@768503|Cytophagia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_4796856_1	1132855.KB913035_gene1911	2.751e-68	235.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
GDHHQS2_k127_4799612_2	497964.CfE428DRAFT_3914	3.063e-58	207.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4799612_1	234267.Acid_0193	9.118e-125	409.0	COG4409@1|root,COG4409@2|Bacteria,3Y7HZ@57723|Acidobacteria	57723|Acidobacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
GDHHQS2_k127_4799612_4	365046.Rta_11140	1.084e-17	89.0	COG2002@1|root,COG2002@2|Bacteria,1QVJI@1224|Proteobacteria,2WH1Z@28216|Betaproteobacteria,4AEYD@80864|Comamonadaceae	28216|Betaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS2_k127_4799612_0	234267.Acid_3468	1.277e-246	770.0	COG1866@1|root,COG1866@2|Bacteria,3Y3U4@57723|Acidobacteria	57723|Acidobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
GDHHQS2_k127_4799612_3	234267.Acid_3467	3.69e-43	162.0	2F4XC@1|root,33XJD@2|Bacteria,3Y7TM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4804033_3	1121957.ATVL01000006_gene2952	7.848e-49	191.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS2_k127_4804033_2	1207076.ALAT01000204_gene1790	1.213e-65	230.0	COG1247@1|root,COG1247@2|Bacteria,1QU4K@1224|Proteobacteria,1T2Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_4804033_1	234267.Acid_1371	1.144e-138	453.0	COG0451@1|root,COG0451@2|Bacteria,3Y3T4@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_4804033_0	234267.Acid_1372	2.299e-209	662.0	COG0247@1|root,COG0247@2|Bacteria,3Y3K8@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GDHHQS2_k127_4806978_1	1340493.JNIF01000004_gene232	6.152e-189	608.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
GDHHQS2_k127_4806978_3	584708.Apau_2272	4.816e-08	58.0	COG4804@1|root,COG4804@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
GDHHQS2_k127_4806978_4	243277.VC_A0433	0.000369	46.0	COG0457@1|root,COG0457@2|Bacteria,1QXRG@1224|Proteobacteria,1T3HP@1236|Gammaproteobacteria,1Y35D@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
GDHHQS2_k127_4806978_0	1267535.KB906767_gene1680	5.076e-295	939.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_4806978_2	234267.Acid_5927	3.694e-66	237.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_4810747_1	68260.JOAY01000047_gene855	4.362e-90	308.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS2_k127_4810747_4	234267.Acid_2176	1.139e-38	150.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4810747_2	485917.Phep_3564	4.584e-55	204.0	COG0667@1|root,COG0667@2|Bacteria,4P099@976|Bacteroidetes,1IVJA@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_4810747_0	357808.RoseRS_1254	9.372e-186	592.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,3771Y@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS2_k127_4810747_3	298654.FraEuI1c_0484	2.868e-46	178.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
GDHHQS2_k127_4810747_5	1210884.HG799475_gene15229	5.479e-27	114.0	COG3119@1|root,COG3119@2|Bacteria,2IYGF@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4814203_0	1340493.JNIF01000003_gene2085	2.781e-136	458.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4814203_1	234267.Acid_1744	3.821e-64	235.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
GDHHQS2_k127_4820249_0	1340493.JNIF01000003_gene4144	3.648e-148	487.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4821574_2	1247726.MIM_c20840	1.904e-10	65.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2W1EH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4821574_3	1217718.ALOU01000005_gene1481	0.0001428	50.0	COG3181@1|root,COG3181@2|Bacteria,1MY36@1224|Proteobacteria,2VJK1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4821574_0	365528.KB891257_gene4784	3.483e-138	458.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_4821574_1	1123504.JQKD01000011_gene2411	4.477e-15	78.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJH2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_4822361_0	765910.MARPU_12740	1.452e-111	385.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXB4@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_4822361_1	1125863.JAFN01000001_gene1054	5.142e-23	108.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
GDHHQS2_k127_4822361_2	1121033.AUCF01000001_gene2487	2.43e-22	107.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2U16R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_4831955_5	886377.Murru_2673	2.504e-42	156.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
GDHHQS2_k127_4831955_0	1267535.KB906767_gene356	4.235e-228	730.0	COG2010@1|root,COG2010@2|Bacteria,3Y6P3@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4831955_1	1267535.KB906767_gene355	5.772e-205	651.0	COG3119@1|root,COG3119@2|Bacteria,3Y6Y5@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4831955_8	768710.DesyoDRAFT_1030	2.048e-12	74.0	COG2050@1|root,COG2050@2|Bacteria,1VJ9F@1239|Firmicutes,24T28@186801|Clostridia,262SI@186807|Peptococcaceae	186801|Clostridia	Q	PFAM thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
GDHHQS2_k127_4831955_4	1286632.P278_24970	1.178e-64	231.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1HXKC@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_4831955_3	331869.BAL199_28565	5.613e-145	469.0	COG1921@1|root,COG1921@2|Bacteria,1MW8F@1224|Proteobacteria,2TSR8@28211|Alphaproteobacteria,4BR1T@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
GDHHQS2_k127_4831955_2	1123508.JH636443_gene5077	4.957e-188	598.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
GDHHQS2_k127_4832102_0	497964.CfE428DRAFT_0997	2.14e-30	125.0	COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS2_k127_4832102_2	748280.NH8B_1148	1.175e-08	55.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4832102_3	760568.Desku_3207	4.623e-05	53.0	COG0553@1|root,COG1476@1|root,COG0553@2|Bacteria,COG1476@2|Bacteria,1TQ5E@1239|Firmicutes,25C98@186801|Clostridia,260VT@186807|Peptococcaceae	186801|Clostridia	L	PFAM DNA RNA helicase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
GDHHQS2_k127_4832102_1	1502724.FF80_01574	4.009e-15	80.0	COG0645@1|root,COG0645@2|Bacteria,1Q3U4@1224|Proteobacteria,2UIA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GDHHQS2_k127_4834786_1	234267.Acid_3181	2.699e-30	122.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3Y4W1@57723|Acidobacteria	57723|Acidobacteria	H	synthase	-	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS2_k127_4834786_0	41431.PCC8801_0005	1.3e-90	304.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GDHHQS2_k127_4834786_2	234267.Acid_5136	2.663e-19	91.0	2CM4K@1|root,2ZCYF@2|Bacteria,3Y96I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4835183_0	1340493.JNIF01000003_gene2191	6.412e-133	429.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS2_k127_4835183_1	234267.Acid_7345	7.612e-75	262.0	COG0500@1|root,COG2226@2|Bacteria,3Y44I@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_4837078_1	419610.Mext_3571	4.247e-15	82.0	COG2244@1|root,COG2244@2|Bacteria,1NIMS@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	pglK	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
GDHHQS2_k127_4837078_0	497964.CfE428DRAFT_2775	2.248e-52	199.0	COG0489@1|root,COG0489@2|Bacteria,46UJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
GDHHQS2_k127_4837691_1	1340493.JNIF01000004_gene234	1.424e-101	349.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4837691_0	1340493.JNIF01000003_gene3558	1.907e-283	880.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
GDHHQS2_k127_4837691_2	1267535.KB906767_gene209	1.463e-62	221.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GDHHQS2_k127_4851301_2	1267535.KB906767_gene976	3.601e-64	222.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS2_k127_4851301_1	1340493.JNIF01000004_gene624	2.094e-110	367.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
GDHHQS2_k127_4851301_0	234267.Acid_4289	7.996e-281	869.0	COG0673@1|root,COG0673@2|Bacteria,3Y6C9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4851816_2	234267.Acid_7651	8.913e-09	62.0	COG1637@1|root,COG1637@2|Bacteria,3Y5TD@57723|Acidobacteria	57723|Acidobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
GDHHQS2_k127_4851816_0	290397.Adeh_1165	8.619e-88	308.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
GDHHQS2_k127_4851816_1	1122165.AUHS01000006_gene633	2.884e-39	155.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1JCGB@118969|Legionellales	118969|Legionellales	IQ	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
GDHHQS2_k127_4855583_0	1267535.KB906767_gene5002	1.338e-182	588.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_4855583_1	1380600.AUYN01000009_gene1068	2.887e-166	547.0	COG3525@1|root,COG3525@2|Bacteria,4NH2R@976|Bacteroidetes,1I12J@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
GDHHQS2_k127_4855583_2	234267.Acid_3073	1.138e-147	473.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_4855583_3	1340493.JNIF01000003_gene4693	4.443e-24	107.0	COG0652@1|root,COG5563@1|root,COG0652@2|Bacteria,COG5563@2|Bacteria,3Y8DZ@57723|Acidobacteria	57723|Acidobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS2_k127_4855963_2	240015.ACP_2349	2.304e-62	219.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS2_k127_4855963_0	401053.AciPR4_4274	3.827e-106	362.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS2_k127_4855963_4	1410670.JHXF01000001_gene2569	5.11e-19	96.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GDHHQS2_k127_4855963_1	204669.Acid345_0217	2.552e-81	293.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria,2JI2B@204432|Acidobacteriia	204432|Acidobacteriia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS2_k127_4855963_3	504472.Slin_1083	5.576e-24	102.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,47RUP@768503|Cytophagia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS2_k127_4855963_5	1192034.CAP_5531	2.05e-10	67.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS2_k127_4855963_6	937777.Deipe_2584	4.318e-10	65.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS2_k127_4857155_1	344747.PM8797T_14594	9.723e-162	521.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4857155_2	1340493.JNIF01000003_gene1551	3.233e-59	210.0	COG2318@1|root,COG2318@2|Bacteria,3Y503@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4857155_0	234267.Acid_6976	2.178e-209	669.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4857558_0	1267535.KB906767_gene3823	9.137e-126	430.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_4860599_4	234267.Acid_6231	4.539e-81	278.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4860599_1	234267.Acid_6230	6.29e-119	395.0	COG0438@1|root,COG0438@2|Bacteria,3Y64B@57723|Acidobacteria	2|Bacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GDHHQS2_k127_4860599_5	1340493.JNIF01000003_gene2970	1.038e-72	258.0	COG0438@1|root,COG0438@2|Bacteria,3Y4B5@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4860599_8	1122604.JONR01000034_gene418	3.131e-08	63.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4860599_7	452637.Oter_2932	6.876e-17	92.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
GDHHQS2_k127_4860599_6	1267534.KB906757_gene1075	2.088e-62	222.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,3Y6YV@57723|Acidobacteria,2JKEW@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_4860599_0	1123242.JH636434_gene5367	1.621e-135	444.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4860599_2	204669.Acid345_3481	3.235e-103	349.0	COG1291@1|root,COG1291@2|Bacteria,3Y3Y8@57723|Acidobacteria,2JI9S@204432|Acidobacteriia	204432|Acidobacteriia	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
GDHHQS2_k127_4860599_3	234267.Acid_5889	9.271e-84	289.0	COG1360@1|root,COG1360@2|Bacteria,3Y47G@57723|Acidobacteria	57723|Acidobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
GDHHQS2_k127_4860599_9	231434.JQJH01000013_gene2952	1.571e-06	55.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2U2PF@28211|Alphaproteobacteria,3NCFI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
GDHHQS2_k127_4862081_1	1128421.JAGA01000002_gene809	1.718e-35	147.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02103,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
GDHHQS2_k127_4862081_0	1267535.KB906767_gene4920	1.583e-79	292.0	COG1629@1|root,COG4771@2|Bacteria,3Y7CC@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4862498_1	234267.Acid_7510	1.061e-240	766.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4862498_4	195250.CM001776_gene3974	0.0002575	49.0	COG4636@1|root,COG4636@2|Bacteria,1G269@1117|Cyanobacteria,1H0JC@1129|Synechococcus	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_4862498_2	530564.Psta_4506	2.712e-128	424.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_4862498_3	1121904.ARBP01000040_gene530	1.183e-82	292.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4862498_0	234267.Acid_7421	0.0	1195.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria	57723|Acidobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS2_k127_4871606_4	1267535.KB906767_gene2729	3.047e-18	87.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria,3Y388@57723|Acidobacteria	57723|Acidobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
GDHHQS2_k127_4871606_3	1340493.JNIF01000003_gene2837	3.074e-121	392.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS2_k127_4871606_0	234267.Acid_2410	0.0	1209.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS2_k127_4871606_1	234267.Acid_3576	2.575e-140	453.0	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
GDHHQS2_k127_4871606_2	234267.Acid_3573	5.669e-123	406.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_4873601_2	1340493.JNIF01000003_gene1475	1.473e-156	510.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4873601_1	1340493.JNIF01000003_gene1474	3.019e-200	653.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4873601_4	1340493.JNIF01000003_gene4382	4.478e-142	464.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4873601_7	401053.AciPR4_2737	5.442e-49	186.0	COG2159@1|root,COG2159@2|Bacteria,3Y7XT@57723|Acidobacteria,2JNXE@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_4873601_5	204669.Acid345_2910	1.185e-135	445.0	COG2271@1|root,COG2271@2|Bacteria,3Y2VG@57723|Acidobacteria,2JIWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_4873601_3	234267.Acid_7363	2.463e-153	499.0	COG3359@1|root,COG3359@2|Bacteria,3Y6WT@57723|Acidobacteria	57723|Acidobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GDHHQS2_k127_4873601_6	1449126.JQKL01000089_gene487	8.994e-85	300.0	COG4279@1|root,COG4279@2|Bacteria,1UZH3@1239|Firmicutes,24DEV@186801|Clostridia	186801|Clostridia	L	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
GDHHQS2_k127_4873601_0	1123508.JH636439_gene662	3.638e-228	717.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
GDHHQS2_k127_4879888_1	1340493.JNIF01000004_gene88	4.571e-133	431.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_4879888_0	234267.Acid_3066	3.05e-138	460.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_489357_5	794903.OPIT5_11955	2.146e-111	381.0	COG2327@1|root,COG2327@2|Bacteria,46YBH@74201|Verrucomicrobia,3K99B@414999|Opitutae	414999|Opitutae	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
GDHHQS2_k127_489357_4	330214.NIDE2011	1.743e-115	392.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria	2|Bacteria	S	type VI secretion protein	sciH	-	-	ko:K11900,ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
GDHHQS2_k127_489357_1	234267.Acid_0019	3.183e-200	646.0	2EY4D@1|root,33RD9@2|Bacteria,3Y6DM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_489357_3	234267.Acid_0020	1.422e-156	516.0	COG0457@1|root,COG0457@2|Bacteria,3Y6VN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_489357_7	102129.Lepto7375DRAFT_5630	1.372e-09	69.0	COG0484@1|root,COG0484@2|Bacteria,1G5QV@1117|Cyanobacteria,1HAZV@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
GDHHQS2_k127_489357_0	234267.Acid_1661	5.285e-236	741.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_489357_2	1340493.JNIF01000003_gene2455	2.061e-170	542.0	COG0075@1|root,COG0075@2|Bacteria,3Y3I6@57723|Acidobacteria	57723|Acidobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_4893636_3	234267.Acid_4171	1.868e-05	49.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_4893636_1	1267535.KB906767_gene2429	2.228e-81	276.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3,RraA-like
GDHHQS2_k127_4893636_2	326427.Cagg_3747	5.285e-31	126.0	COG0727@1|root,32S46@2|Bacteria,2G78K@200795|Chloroflexi,377J9@32061|Chloroflexia	32061|Chloroflexia	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GDHHQS2_k127_4893636_0	596154.Alide2_1766	1.55e-103	345.0	COG1388@1|root,COG1388@2|Bacteria,1MY1S@1224|Proteobacteria,2VZIM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
GDHHQS2_k127_4894564_5	1121451.DESAM_10078	1.771e-05	48.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_4894564_0	234267.Acid_5315	0.0	1427.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_4894564_3	706587.Desti_1430	2.6e-55	203.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2WQ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
GDHHQS2_k127_4894564_1	234267.Acid_1342	7.247e-93	322.0	COG1957@1|root,COG1957@2|Bacteria,3Y5WG@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
GDHHQS2_k127_4894564_2	234267.Acid_1117	9.566e-70	238.0	COG1301@1|root,COG1301@2|Bacteria,3Y2G6@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2	-	-	SDF
GDHHQS2_k127_4900821_2	234267.Acid_0689	6.528e-38	144.0	COG3093@1|root,COG3093@2|Bacteria,3Y5MG@57723|Acidobacteria	2|Bacteria	K	TIGRFAM Addiction module antidote protein, HigA	vapL	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
GDHHQS2_k127_4900821_0	1267535.KB906767_gene3199	7.347e-224	710.0	COG3250@1|root,COG3250@2|Bacteria,3Y48R@57723|Acidobacteria,2JKSM@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
GDHHQS2_k127_4900821_1	234267.Acid_6833	4.712e-56	211.0	COG0823@1|root,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_4907077_3	234267.Acid_2722	2.317e-06	53.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_4907077_1	1267535.KB906767_gene3277	2.116e-151	502.0	COG4122@1|root,COG4122@2|Bacteria,3Y33U@57723|Acidobacteria	57723|Acidobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4907077_0	1340493.JNIF01000004_gene178	3.837e-157	527.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,Reprolysin_3
GDHHQS2_k127_4907077_4	1384054.N790_01735	0.0008097	47.0	COG0346@1|root,COG0346@2|Bacteria,1NB98@1224|Proteobacteria,1SS2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_4910468_0	1047013.AQSP01000131_gene1840	8.987e-60	226.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS2_k127_4911653_1	234267.Acid_1227	3.314e-125	434.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1227|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4911653_4	234267.Acid_6216	1.939e-89	301.0	COG1212@1|root,COG1212@2|Bacteria,3Y4GZ@57723|Acidobacteria	57723|Acidobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS2_k127_4911653_0	1267535.KB906767_gene621	1.532e-296	917.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS2_k127_4911653_2	234267.Acid_6214	1.102e-115	383.0	COG2877@1|root,COG2877@2|Bacteria,3Y2WF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM DAHP synthetase I	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS2_k127_4911653_6	221288.JH992901_gene5628	1.002e-19	94.0	COG1598@1|root,COG1598@2|Bacteria,1G978@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4911653_3	1476583.DEIPH_ctg004orf0154	2.809e-95	321.0	COG1028@1|root,COG1028@2|Bacteria,1WJ80@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_4911653_7	661478.OP10G_2561	5.883e-15	78.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
GDHHQS2_k127_4911653_8	234267.Acid_2664	2.557e-08	59.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
GDHHQS2_k127_4911653_5	1340493.JNIF01000004_gene904	1.118e-21	97.0	2EMD6@1|root,33F24@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4914365_1	714943.Mucpa_2626	4.693e-14	77.0	COG0845@1|root,COG0845@2|Bacteria,4NH4Z@976|Bacteroidetes,1INZ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_4914365_0	234267.Acid_5518	0.0	1196.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_4916162_1	234267.Acid_1595	1.333e-97	323.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_4916162_7	1183438.GKIL_3544	2.873e-18	89.0	COG1716@1|root,COG1716@2|Bacteria,1G9NG@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
GDHHQS2_k127_4916162_5	448385.sce2478	5.08e-41	163.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123,FHA,GAF_2,Yop-YscD_cpl
GDHHQS2_k127_4916162_6	215803.DB30_6894	5.06e-40	149.0	COG5649@1|root,COG5649@2|Bacteria,1PCA0@1224|Proteobacteria,438XC@68525|delta/epsilon subdivisions,2X42P@28221|Deltaproteobacteria,2YY3P@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_4916162_2	1382356.JQMP01000001_gene964	3.578e-96	329.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi,27YY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_4916162_3	344747.PM8797T_03199	1.116e-86	305.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_4916162_4	485913.Krac_8169	2.085e-58	216.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_4916162_0	344747.PM8797T_03199	1.126e-98	334.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_4916162_8	234267.Acid_0194	4.217e-06	51.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_4916288_10	211165.AJLN01000050_gene5318	5.545e-07	54.0	COG1487@1|root,COG1487@2|Bacteria,1G8EC@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GDHHQS2_k127_4916288_2	234267.Acid_2559	1.175e-129	426.0	COG0786@1|root,COG0786@2|Bacteria	2|Bacteria	P	glutamate:sodium symporter activity	gltS	GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015501,GO:0015672,GO:0015711,GO:0015849,GO:0016020,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	iIT341.HP1506,iPC815.YPO0035,iZ_1308.Z5081	Glt_symporter
GDHHQS2_k127_4916288_0	234267.Acid_3945	2.361e-265	829.0	COG0043@1|root,COG0043@2|Bacteria,3Y3BY@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GDHHQS2_k127_4916288_5	1340493.JNIF01000004_gene817	2.513e-88	297.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	57723|Acidobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_4916288_3	314345.SPV1_04838	5.109e-107	364.0	COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria	1224|Proteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
GDHHQS2_k127_4916288_7	215803.DB30_1906	1.088e-51	203.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,439T1@68525|delta/epsilon subdivisions,2X563@28221|Deltaproteobacteria,2Z05Z@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
GDHHQS2_k127_4916288_8	234267.Acid_3219	2.102e-34	150.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4916288_6	886293.Sinac_1894	1.511e-67	245.0	29CVJ@1|root,2ZZTQ@2|Bacteria,2IZ72@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4916288_1	1340493.JNIF01000003_gene2893	3.03e-172	546.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
GDHHQS2_k127_4916288_9	1340493.JNIF01000003_gene3506	4.453e-10	61.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GDHHQS2_k127_4916843_2	497964.CfE428DRAFT_6228	2.014e-71	262.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	2|Bacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS2_k127_4916843_4	1121378.KB899695_gene3058	2.767e-05	51.0	COG0454@1|root,COG0456@2|Bacteria,1WKCN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_4916843_1	1340493.JNIF01000003_gene1841	1.902e-115	383.0	COG0810@1|root,COG0810@2|Bacteria,3Y3Q0@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_4916843_0	1267535.KB906767_gene99	0.0	1296.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS2_k127_4916843_3	1267535.KB906767_gene97	3.748e-23	101.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_4917466_3	1340493.JNIF01000004_gene349	8.261e-56	197.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS2_k127_4917466_2	1340493.JNIF01000004_gene350	1.93e-108	357.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GDHHQS2_k127_4917466_0	234267.Acid_0465	2.887e-264	820.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS2_k127_4917466_5	204669.Acid345_4331	1.674e-28	119.0	COG0355@1|root,COG0355@2|Bacteria,3Y515@57723|Acidobacteria,2JJJV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
GDHHQS2_k127_4917466_4	247490.KSU1_B0210	1.365e-37	143.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_32
GDHHQS2_k127_4917466_1	237609.PSAKL28_31720	8.186e-170	541.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_4922001_12	1313172.YM304_03450	4.034e-42	178.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	MA20_05265	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4922001_6	497964.CfE428DRAFT_3577	1.329e-101	342.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S9
GDHHQS2_k127_4922001_5	1267535.KB906767_gene3454	1.984e-121	400.0	COG4299@1|root,COG4299@2|Bacteria,3Y3Q4@57723|Acidobacteria	2|Bacteria	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
GDHHQS2_k127_4922001_0	886293.Sinac_5717	3.935e-245	769.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4922001_8	234267.Acid_5253	3.588e-86	294.0	COG0546@1|root,COG0546@2|Bacteria,3Y4RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS2_k127_4922001_7	314230.DSM3645_24005	3.673e-88	305.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_4922001_15	172088.AUGA01000020_gene3550	2.899e-07	57.0	COG1705@1|root,COG1705@2|Bacteria,1Q6GA@1224|Proteobacteria,2VCM5@28211|Alphaproteobacteria,3K56M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MNU	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4922001_11	682795.AciX8_1480	1.584e-48	188.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GDHHQS2_k127_4922001_16	2903.EOD12488	1.373e-05	59.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_4,TPR_7,TPR_8
GDHHQS2_k127_4922001_1	1340493.JNIF01000003_gene3445	5.903e-200	646.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4922001_2	1340493.JNIF01000003_gene3446	1.065e-174	559.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4922001_10	926566.Terro_0838	1.508e-52	194.0	COG3403@1|root,COG3403@2|Bacteria,3Y7H4@57723|Acidobacteria	57723|Acidobacteria	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4922001_3	1267535.KB906767_gene1287	7.533e-169	545.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_4922001_14	234267.Acid_3123	1.767e-32	136.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_4922001_9	13690.CP98_04247	1.252e-82	290.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,2U55E@28211|Alphaproteobacteria,2K2ZN@204457|Sphingomonadales	204457|Sphingomonadales	G	Sugar (and other) transporter	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_4922001_4	497964.CfE428DRAFT_0149	1.012e-155	502.0	COG0644@1|root,COG0644@2|Bacteria,46SNN@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_492265_2	1267535.KB906767_gene4947	1.532e-92	311.0	COG0076@1|root,COG0076@2|Bacteria,3Y2SW@57723|Acidobacteria,2JMFG@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS2_k127_492265_3	234267.Acid_0555	3.905e-84	291.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GDHHQS2_k127_492265_0	448385.sce5134	0.0	1120.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42Z54@68525|delta/epsilon subdivisions,2WUB9@28221|Deltaproteobacteria,2YYC4@29|Myxococcales	28221|Deltaproteobacteria	J	Anticodon-binding domain of tRNA	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS2_k127_492265_1	234267.Acid_7731	1.221e-129	417.0	COG2022@1|root,COG2022@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
GDHHQS2_k127_492265_7	1397666.RS24_01174	3.446e-16	85.0	2F81H@1|root,340EZ@2|Bacteria,1N5WY@1224|Proteobacteria,2UEF2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_492265_4	204669.Acid345_4011	1.9e-35	139.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_492265_6	158500.BV97_04222	8.84e-26	113.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UF2T@28211|Alphaproteobacteria,2K65Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
GDHHQS2_k127_492265_5	861299.J421_5889	1.271e-34	139.0	2DSP1@1|root,33GVU@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
GDHHQS2_k127_492265_8	1444770.AF72_04570	1.155e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,1RP3U@1236|Gammaproteobacteria,1X5KU@135614|Xanthomonadales	135614|Xanthomonadales	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
GDHHQS2_k127_4923059_4	1123269.NX02_13500	2.632e-20	106.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_4923059_2	234267.Acid_4320	2.46e-76	271.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4923059_1	234267.Acid_4321	1.393e-97	343.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_4923059_3	234267.Acid_0838	2.614e-68	237.0	COG0243@1|root,COG0243@2|Bacteria,3Y7US@57723|Acidobacteria	57723|Acidobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
GDHHQS2_k127_4923059_0	1123487.KB892834_gene3003	1.039e-204	652.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,2KU82@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS2_k127_4934099_0	1267535.KB906767_gene765	3.681e-174	557.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_4934099_1	234267.Acid_4307	4.536e-85	286.0	COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria	57723|Acidobacteria	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_4935290_1	1121479.AUBS01000004_gene2442	1.63e-06	60.0	COG2518@1|root,COG2518@2|Bacteria,1R9VH@1224|Proteobacteria,2U6AJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Met_10,Methyltransf_21
GDHHQS2_k127_4935290_0	1484460.JSWG01000007_gene3087	2.071e-12	78.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS2_k127_4935701_0	153721.MYP_2286	5.158e-99	340.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47ND1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_4935701_1	1340493.JNIF01000003_gene4261	2.619e-45	171.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
GDHHQS2_k127_4935701_2	1089547.KB913013_gene114	3.534e-17	91.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS2_k127_4938008_0	497321.C664_15398	3.299e-53	207.0	COG3468@1|root,COG3468@2|Bacteria,1MXH3@1224|Proteobacteria,2WHV1@28216|Betaproteobacteria,2KZQD@206389|Rhodocyclales	206389|Rhodocyclales	MU	Nidogen-like	-	-	-	-	-	-	-	-	-	-	-	-	NIDO,VPEP
GDHHQS2_k127_4938328_2	1340493.JNIF01000003_gene3743	4.681e-67	229.0	COG1172@1|root,COG1172@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS2_k127_4938328_0	1340493.JNIF01000003_gene1534	2.46e-278	868.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	BNR,BNR_2,CBM_2,RicinB_lectin_2
GDHHQS2_k127_4938328_3	861299.J421_2505	3.329e-58	212.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS2_k127_4938328_1	234267.Acid_5471	9.324e-118	407.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_4938328_4	234267.Acid_5471	6.21e-21	99.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_4939968_5	344747.PM8797T_00522	1.866e-22	97.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
GDHHQS2_k127_4939968_2	517722.AEUE01000003_gene1465	1.122e-139	457.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,HYR,VCBS
GDHHQS2_k127_4939968_6	1005048.CFU_0548	6.117e-08	57.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2VSZ8@28216|Betaproteobacteria,47701@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
GDHHQS2_k127_4939968_0	1333998.M2A_0880	1.713e-178	589.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
GDHHQS2_k127_4939968_3	1144275.COCOR_05087	5.772e-138	456.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42QAU@68525|delta/epsilon subdivisions,2WMD2@28221|Deltaproteobacteria,2YUNE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_4939968_1	1267535.KB906767_gene5356	1.774e-148	480.0	COG1641@1|root,COG1641@2|Bacteria,3Y42R@57723|Acidobacteria,2JI6G@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GDHHQS2_k127_4939968_4	234267.Acid_7056	7.849e-79	268.0	COG0846@1|root,COG0846@2|Bacteria,3Y4T9@57723|Acidobacteria	57723|Acidobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS2_k127_4944811_5	234267.Acid_5171	6.353e-06	50.0	COG0438@1|root,COG0438@2|Bacteria,3Y7XP@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4944811_2	234267.Acid_5172	3.169e-82	281.0	COG1989@1|root,COG1989@2|Bacteria,3Y4VX@57723|Acidobacteria	57723|Acidobacteria	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS2_k127_4944811_1	1340493.JNIF01000004_gene1008	1.923e-177	567.0	COG1207@1|root,COG1207@2|Bacteria,3Y3SI@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS2_k127_4944811_3	189753.AXAS01000001_gene3584	1.865e-51	198.0	COG1409@1|root,COG1409@2|Bacteria,1NA5Y@1224|Proteobacteria,2V984@28211|Alphaproteobacteria,3K1J3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_4944811_0	234267.Acid_7597	1.137e-272	857.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bgaB	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
GDHHQS2_k127_4944811_4	765911.Thivi_2393	4.751e-11	73.0	COG5464@1|root,COG5464@2|Bacteria,1PXZD@1224|Proteobacteria,1RQBS@1236|Gammaproteobacteria,1WXJI@135613|Chromatiales	135613|Chromatiales	S	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GDHHQS2_k127_4945075_0	234267.Acid_2982	2.964e-246	781.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4945075_4	234267.Acid_5424	2.861e-49	188.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
GDHHQS2_k127_4945075_5	485913.Krac_5638	1.221e-30	135.0	COG1503@1|root,COG1503@2|Bacteria,2G6UJ@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4945075_3	1267535.KB906767_gene2762	3.021e-54	197.0	COG2197@1|root,COG2197@2|Bacteria,3Y8CY@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4945075_2	234267.Acid_1587	6.272e-143	471.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS2_k127_4945075_1	1340493.JNIF01000003_gene2091	2.502e-150	487.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_494551_4	760192.Halhy_2301	4.393e-19	93.0	COG1595@1|root,COG1595@2|Bacteria,4NK4D@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
GDHHQS2_k127_494551_2	1489678.RDMS_09680	3.196e-32	129.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_494551_6	402881.Plav_1338	0.0001577	49.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2UEV4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
GDHHQS2_k127_494551_3	32057.KB217478_gene2274	3.473e-20	93.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_494551_0	234267.Acid_0689	2.67e-39	148.0	COG3093@1|root,COG3093@2|Bacteria,3Y5MG@57723|Acidobacteria	2|Bacteria	K	TIGRFAM Addiction module antidote protein, HigA	vapL	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
GDHHQS2_k127_494551_1	234267.Acid_0688	2.903e-34	133.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS2_k127_4951420_3	1134413.ANNK01000096_gene686	3.244e-14	76.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
GDHHQS2_k127_4951420_1	1125973.JNLC01000010_gene1874	8.424e-70	243.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2TV1R@28211|Alphaproteobacteria,3K6GG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GDHHQS2_k127_4951420_0	639030.JHVA01000001_gene3197	1.201e-269	867.0	COG1629@1|root,COG4771@2|Bacteria,3Y6PD@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_4951420_2	234267.Acid_2606	7.104e-35	135.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	celD	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calycin_like,CelD_N,DUF1080,Glyco_hydro_9,PCMD
GDHHQS2_k127_4951752_2	886293.Sinac_5965	6.684e-10	64.0	COG0526@1|root,COG2010@1|root,COG0526@2|Bacteria,COG2010@2|Bacteria,2IWVQ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C
GDHHQS2_k127_4951752_1	1035191.HMPREF0185_00318	2.758e-118	391.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,2TTUZ@28211|Alphaproteobacteria,2KFTZ@204458|Caulobacterales	204458|Caulobacterales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
GDHHQS2_k127_4951752_3	398578.Daci_4515	1.384e-09	72.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
GDHHQS2_k127_4951752_0	344747.PM8797T_24121	9.598e-145	476.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	2|Bacteria	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_4952365_2	243090.RB8150	0.0001411	45.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4952365_0	234267.Acid_4748	1.821e-81	290.0	COG1858@1|root,COG1858@2|Bacteria,3Y7FY@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
GDHHQS2_k127_4952365_1	1267533.KB906733_gene3215	2.357e-72	260.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_4958965_2	864069.MicloDRAFT_00009890	5.983e-31	129.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,1JTF0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
GDHHQS2_k127_4958965_0	189753.AXAS01000041_gene2534	6.131e-70	249.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
GDHHQS2_k127_4958965_1	296591.Bpro_4079	9.21e-34	131.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2VJA3@28216|Betaproteobacteria,4ABMN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_4959313_2	234267.Acid_0174	7.517e-50	181.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_4959313_1	234267.Acid_7029	9.956e-78	274.0	COG1295@1|root,COG1295@2|Bacteria,3Y3AJ@57723|Acidobacteria	57723|Acidobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS2_k127_4959313_0	314230.DSM3645_24380	1.414e-107	354.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_4959313_3	1379698.RBG1_1C00001G0930	4.566e-10	69.0	COG0432@1|root,COG0432@2|Bacteria,2NPB7@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS2_k127_4965455_0	234267.Acid_3952	2.678e-286	904.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_4965455_4	1267534.KB906755_gene4530	2.775e-07	53.0	COG1695@1|root,COG1695@2|Bacteria,3Y55J@57723|Acidobacteria,2JJQ9@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_4965455_3	29581.BW37_04120	5.138e-25	115.0	COG2159@1|root,COG2159@2|Bacteria,1R73N@1224|Proteobacteria,2VQVU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_4965455_1	29581.BW37_04120	1.899e-40	161.0	COG2159@1|root,COG2159@2|Bacteria,1R73N@1224|Proteobacteria,2VQVU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_4965455_2	158190.SpiGrapes_2538	5.654e-37	151.0	COG1864@1|root,COG1864@2|Bacteria,2J7IP@203691|Spirochaetes	203691|Spirochaetes	V	DNA RNA non-specific endonuclease	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_4965455_5	234267.Acid_0944	1.934e-05	48.0	2E1AY@1|root,32WQW@2|Bacteria,3Y8WG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4967159_1	234267.Acid_5825	6.733e-52	188.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
GDHHQS2_k127_4967159_0	1267535.KB906767_gene423	0.0	1124.0	COG1649@1|root,COG1649@2|Bacteria,3Y6SC@57723|Acidobacteria,2JM8G@204432|Acidobacteriia	204432|Acidobacteriia	S	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
GDHHQS2_k127_4970358_0	1403819.BATR01000162_gene5413	7.52e-128	418.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_4971177_0	234267.Acid_5958	1.458e-191	604.0	COG4952@1|root,COG4952@2|Bacteria,3Y3J5@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Xylose isomerase	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_4971405_6	32057.KB217480_gene8180	1.142e-12	75.0	COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1HK8V@1161|Nostocales	1117|Cyanobacteria	J	TIGRFAM endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_4971405_1	234267.Acid_6148	4.106e-112	381.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4971405_0	1340493.JNIF01000003_gene2948	2.987e-142	459.0	COG0167@1|root,COG0167@2|Bacteria,3Y2K1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS2_k127_4971405_5	204669.Acid345_0174	7.397e-48	174.0	COG0251@1|root,COG0251@2|Bacteria,3Y5DN@57723|Acidobacteria,2JN2R@204432|Acidobacteriia	204432|Acidobacteriia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_4971405_2	234267.Acid_5283	1.023e-108	363.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS2_k127_4971405_4	1117108.PAALTS15_17566	2.12e-57	208.0	COG1028@1|root,COG1028@2|Bacteria,1V05R@1239|Firmicutes,4HDCM@91061|Bacilli,26S71@186822|Paenibacillaceae	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	yusR	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
GDHHQS2_k127_4971405_3	1340493.JNIF01000003_gene2622	7.631e-84	284.0	COG1105@1|root,COG1105@2|Bacteria,3Y5F9@57723|Acidobacteria	57723|Acidobacteria	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS2_k127_4983466_0	330084.JNYZ01000001_gene3252	5.278e-44	178.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_5009638_0	234267.Acid_4618	2.439e-160	516.0	COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria	57723|Acidobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GDHHQS2_k127_5009638_1	1280954.HPO_10135	6.105e-37	142.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,43XXW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS2_k127_5013127_2	1267535.KB906767_gene1234	4.439e-07	56.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
GDHHQS2_k127_5013127_0	1038866.KB902824_gene1251	1.143e-130	428.0	COG1804@1|root,COG1804@2|Bacteria,1MVK4@1224|Proteobacteria,2TWRE@28211|Alphaproteobacteria,3JSRH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	MA20_17775	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS2_k127_5013127_1	234267.Acid_1642	1.036e-108	376.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1642|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5030239_0	1267535.KB906767_gene3083	7.381e-204	650.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5030239_2	1267535.KB906767_gene289	1.069e-09	71.0	297M3@1|root,2ZUU3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5030239_1	1303518.CCALI_00896	6.523e-34	147.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_5031312_0	234267.Acid_0776	2.022e-97	335.0	COG0300@1|root,COG0300@2|Bacteria,3Y5F6@57723|Acidobacteria	57723|Acidobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_5031312_2	1267535.KB906767_gene4292	5.732e-58	209.0	COG2802@1|root,COG2802@2|Bacteria,3Y7UX@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LON_substr_bdg
GDHHQS2_k127_5031312_1	234267.Acid_0773	1.594e-74	260.0	COG1011@1|root,COG1011@2|Bacteria,3Y4BM@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS2_k127_5031312_3	479434.Sthe_3117	1.248e-07	61.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_503364_0	1045855.DSC_03395	6.966e-63	227.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_503364_1	234267.Acid_4418	2.969e-45	177.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5037538_0	234267.Acid_7341	8.271e-176	559.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_5037538_1	237727.NAP1_07485	3.261e-26	117.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,2UG7N@28211|Alphaproteobacteria,2K47E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5037538_2	1340493.JNIF01000003_gene2191	6.23e-13	73.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS2_k127_5039423_1	234267.Acid_0798	2.112e-156	505.0	COG4805@1|root,COG4805@2|Bacteria,3Y468@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS2_k127_5039423_5	234267.Acid_3431	1.098e-66	232.0	COG0727@1|root,COG0727@2|Bacteria,3Y7XA@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GDHHQS2_k127_5039423_3	204669.Acid345_3127	2.995e-78	268.0	COG0500@1|root,COG2226@2|Bacteria,3Y8WR@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_5039423_2	234267.Acid_5351	4.741e-93	312.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria	57723|Acidobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS2_k127_5039423_6	1340493.JNIF01000003_gene1539	1.675e-43	166.0	COG0597@1|root,COG0597@2|Bacteria,3Y55H@57723|Acidobacteria	57723|Acidobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS2_k127_5039423_0	234267.Acid_5353	0.0	1338.0	COG0060@1|root,COG0060@2|Bacteria,3Y3JW@57723|Acidobacteria	57723|Acidobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
GDHHQS2_k127_5039423_7	357808.RoseRS_1474	2.823e-42	162.0	COG0758@1|root,COG0758@2|Bacteria	2|Bacteria	LU	DNA mediated transformation	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS2_k127_5039423_4	883158.HMPREF9140_00968	1.663e-71	257.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,2FQ1D@200643|Bacteroidia	976|Bacteroidetes	L	COG1002 Type II restriction enzyme methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
GDHHQS2_k127_5040662_2	886293.Sinac_7120	3.194e-104	356.0	COG3386@1|root,COG3386@2|Bacteria,2IXCR@203682|Planctomycetes	203682|Planctomycetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_5040662_6	234267.Acid_7667	6.174e-49	191.0	COG1310@1|root,COG1310@2|Bacteria,3Y8K0@57723|Acidobacteria	57723|Acidobacteria	S	metal-dependent protease of the Pad1 Jab1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5040662_0	234267.Acid_1405	3.493e-146	473.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS2_k127_5040662_4	234267.Acid_1404	5.798e-64	226.0	COG0315@1|root,COG0315@2|Bacteria,3Y4IY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS2_k127_5040662_5	234267.Acid_1403	9.634e-56	206.0	COG0521@1|root,COG0521@2|Bacteria,3Y504@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM molybdenum cofactor synthesis	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
GDHHQS2_k127_5040662_3	1340493.JNIF01000003_gene3658	4.084e-103	351.0	COG1240@1|root,COG1240@2|Bacteria,3Y474@57723|Acidobacteria	57723|Acidobacteria	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_5040662_7	278957.ABEA03000095_gene4585	0.0003352	48.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_5040662_1	1206777.B195_18006	9.521e-109	372.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1ZA50@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_5043656_0	1267535.KB906767_gene766	3.99e-142	473.0	COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria	57723|Acidobacteria	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_5043656_1	926569.ANT_25800	5.577e-88	301.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5046793_0	1382306.JNIM01000001_gene1553	8.709e-36	139.0	COG1506@1|root,COG1506@2|Bacteria,2GA6W@200795|Chloroflexi	200795|Chloroflexi	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_5046793_4	457429.ABJI02000018_gene1102	1.171e-06	51.0	COG2133@1|root,COG2133@2|Bacteria,2GRVP@201174|Actinobacteria	201174|Actinobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,DUF1080,PA14
GDHHQS2_k127_5046793_3	187303.BN69_2195	1.097e-09	64.0	arCOG09463@1|root,2Z8U6@2|Bacteria,1NHE7@1224|Proteobacteria,2U24C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DNA-sulfur modification-associated	-	-	-	ko:K19169	-	-	-	-	ko00000,ko02048	-	-	-	DndB
GDHHQS2_k127_5046793_2	1173023.KE650771_gene2128	5.771e-13	73.0	COG2442@1|root,COG2442@2|Bacteria,1G9A4@1117|Cyanobacteria,1JMGK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_5046793_1	1173023.KE650771_gene1228	1.376e-28	118.0	COG4634@1|root,COG4634@2|Bacteria,1G7AE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_10	1267535.KB906767_gene1560	2.745e-45	168.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria,2JIPA@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS2_k127_5061569_7	234267.Acid_0601	4.822e-91	310.0	COG1912@1|root,COG1912@2|Bacteria,3Y50E@57723|Acidobacteria	57723|Acidobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
GDHHQS2_k127_5061569_1	234267.Acid_1908	5.636e-162	517.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3Y339@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GDHHQS2_k127_5061569_12	1340493.JNIF01000003_gene3933	1.423e-43	168.0	COG1286@1|root,COG1286@2|Bacteria,3Y59W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
GDHHQS2_k127_5061569_2	234267.Acid_5250	9.63e-133	428.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria	57723|Acidobacteria	F	PFAM SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS2_k127_5061569_8	1267535.KB906767_gene4993	3.939e-75	258.0	COG0652@1|root,COG0652@2|Bacteria,3Y4CX@57723|Acidobacteria,2JJ67@204432|Acidobacteriia	204432|Acidobacteriia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS2_k127_5061569_5	1267535.KB906767_gene1797	1.452e-100	335.0	COG1735@1|root,COG1735@2|Bacteria,3Y646@57723|Acidobacteria,2JM01@204432|Acidobacteriia	204432|Acidobacteriia	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_18	870187.Thini_3184	0.0008562	43.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria,1ST82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_16	1229780.BN381_210013	3.365e-17	87.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS2_k127_5061569_6	234267.Acid_1600	1.441e-98	343.0	COG1450@1|root,COG1450@2|Bacteria,3Y6Z6@57723|Acidobacteria	57723|Acidobacteria	NU	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
GDHHQS2_k127_5061569_0	1340493.JNIF01000003_gene2437	2.789e-195	617.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_5061569_17	234267.Acid_3394	7.556e-06	53.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_3394|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_14	761193.Runsl_3999	2.001e-27	122.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5061569_4	1379270.AUXF01000002_gene1297	5.748e-104	346.0	COG0596@1|root,COG0596@2|Bacteria,1ZUZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_3	1340493.JNIF01000003_gene4303	3.718e-118	391.0	COG3616@1|root,COG3616@2|Bacteria,3Y7EX@57723|Acidobacteria	57723|Acidobacteria	E	Putative serine dehydratase domain	-	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS2_k127_5061569_13	1340493.JNIF01000003_gene4304	1.335e-41	161.0	2FHG9@1|root,349AB@2|Bacteria,3Y8GZ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_15	1340493.JNIF01000003_gene3708	1.449e-24	106.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5061569_9	234267.Acid_2565	3.68e-74	257.0	COG0164@1|root,COG0164@2|Bacteria,3Y49K@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS2_k127_5061569_11	1267535.KB906767_gene3059	6.864e-44	160.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS2_k127_5065046_2	1267535.KB906767_gene3470	1.423e-130	422.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_5065046_1	234267.Acid_5545	2.427e-174	554.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_5065046_4	234267.Acid_0704	2.363e-17	91.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_5065046_0	234267.Acid_6646	7.075e-193	609.0	COG0641@1|root,COG0641@2|Bacteria,3Y8KB@57723|Acidobacteria	57723|Acidobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
GDHHQS2_k127_5065046_3	456442.Mboo_0012	5.886e-36	145.0	COG4912@1|root,arCOG05122@2157|Archaea,2XWYV@28890|Euryarchaeota,2N9IE@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_5065489_5	234267.Acid_1073	3.458e-88	293.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_5065489_7	1267535.KB906767_gene2647	3.633e-31	131.0	COG0721@1|root,COG0721@2|Bacteria,3Y5QA@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS2_k127_5065489_8	234267.Acid_1075	4.653e-19	101.0	COG5512@1|root,COG5512@2|Bacteria,3Y95D@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
GDHHQS2_k127_5065489_1	1340493.JNIF01000004_gene88	2.048e-279	898.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_5065489_3	909663.KI867150_gene786	2.788e-143	476.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_5065489_6	1395516.PMO01_11405	8.824e-83	282.0	COG1432@1|root,COG1432@2|Bacteria,1R9SC@1224|Proteobacteria,1S5WX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
GDHHQS2_k127_5065489_4	1267535.KB906767_gene2614	1.372e-133	434.0	COG0673@1|root,COG0673@2|Bacteria,3Y32B@57723|Acidobacteria,2JIB3@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_5065489_0	234267.Acid_3731	0.0	1341.0	2EXAB@1|root,33QKZ@2|Bacteria,3Y6WS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5065489_2	1340493.JNIF01000004_gene551	8.802e-155	494.0	COG2304@1|root,COG2304@2|Bacteria,3Y6RY@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_5065489_9	1340493.JNIF01000003_gene2168	5.662e-15	77.0	2E23W@1|root,32XB6@2|Bacteria,3Y5B9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_506898_0	234267.Acid_7044	2.732e-85	297.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,3Y4NJ@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_506898_1	1340493.JNIF01000003_gene1379	2.612e-72	254.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,DUF5122,He_PIG,NHL
GDHHQS2_k127_5094703_0	497964.CfE428DRAFT_3131	9.763e-88	299.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,ThuA
GDHHQS2_k127_5096983_1	861299.J421_5946	1.619e-107	365.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_5096983_3	717772.THIAE_02795	3.664e-33	132.0	COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,1S95Z@1236|Gammaproteobacteria,462M5@72273|Thiotrichales	72273|Thiotrichales	M	SprA-related family	-	-	-	-	-	-	-	-	-	-	-	-	SprA-related
GDHHQS2_k127_5096983_2	509635.N824_00675	3.161e-73	261.0	COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,1IUSW@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme, N-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5096983_0	886293.Sinac_0922	2.711e-157	512.0	COG2271@1|root,COG2271@2|Bacteria,2IYNX@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5096983_4	1340493.JNIF01000003_gene4593	1.873e-32	139.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS2_k127_5097587_0	502025.Hoch_2041	3.473e-49	187.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5101577_1	1340493.JNIF01000003_gene2457	1.224e-12	68.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS2_k127_5101577_0	234267.Acid_5471	8.484e-124	423.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_5106485_1	379066.GAU_0070	7.583e-112	386.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZUF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5106485_3	234267.Acid_7677	3.055e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_5106485_0	1267535.KB906767_gene825	1.753e-118	391.0	COG1940@1|root,COG1940@2|Bacteria,3Y4DD@57723|Acidobacteria,2JJ4T@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_5106485_2	383372.Rcas_0916	4.503e-106	358.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_5106630_1	616991.JPOO01000001_gene4160	1.388e-13	82.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1HY6W@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_5106630_0	886293.Sinac_2212	8.347e-121	393.0	COG3293@1|root,COG3293@2|Bacteria,2IY34@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
GDHHQS2_k127_5117481_6	234267.Acid_4118	4.135e-07	56.0	297ZP@1|root,2ZV5T@2|Bacteria,3Y972@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5117481_5	234267.Acid_4119	1.345e-18	89.0	28VY7@1|root,2ZHZF@2|Bacteria,3Y97D@57723|Acidobacteria	57723|Acidobacteria	S	Conserved hypothetical protein 2217 (DUF2460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
GDHHQS2_k127_5117481_4	234267.Acid_4120	1.7e-29	127.0	28VY7@1|root,3470P@2|Bacteria,3Y8J4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5117481_0	234267.Acid_4121	0.0	1077.0	COG4733@1|root,COG4733@2|Bacteria,3Y67A@57723|Acidobacteria	57723|Acidobacteria	S	Putative phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage-tail_3
GDHHQS2_k127_5117481_1	234267.Acid_4122	8.615e-310	974.0	COG4386@1|root,COG4386@2|Bacteria,3Y65A@57723|Acidobacteria	57723|Acidobacteria	S	tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5117481_3	234267.Acid_1810	2.557e-91	308.0	COG1119@1|root,COG1119@2|Bacteria,3Y2Z4@57723|Acidobacteria	57723|Acidobacteria	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS2_k127_5117481_2	1267535.KB906767_gene1145	1.193e-209	661.0	COG0008@1|root,COG0008@2|Bacteria,3Y465@57723|Acidobacteria,2JHZW@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS2_k127_5117481_7	234267.Acid_5013	3.356e-06	49.0	COG2192@1|root,COG2192@2|Bacteria,3Y6AX@57723|Acidobacteria	57723|Acidobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS2_k127_5123217_5	639030.JHVA01000001_gene2972	8.637e-21	99.0	COG1629@1|root,COG4771@2|Bacteria,3Y6HD@57723|Acidobacteria,2JKQR@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5123217_0	1267535.KB906767_gene4658	5.529e-239	749.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,3Y3TK@57723|Acidobacteria,2JIM5@204432|Acidobacteriia	204432|Acidobacteriia	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
GDHHQS2_k127_5123217_1	1267535.KB906767_gene4657	1.759e-143	469.0	COG3852@1|root,COG3852@2|Bacteria,3Y3JR@57723|Acidobacteria,2JIY1@204432|Acidobacteriia	204432|Acidobacteriia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
GDHHQS2_k127_5123217_2	204669.Acid345_2986	7.696e-116	378.0	COG0580@1|root,COG0580@2|Bacteria,3Y3AE@57723|Acidobacteria,2JIP3@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
GDHHQS2_k127_5123217_7	1340493.JNIF01000003_gene2900	2.374e-09	68.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07004,ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	ASH,CHU_C,DUF11,SGL
GDHHQS2_k127_5123217_4	118173.KB235910_gene4983	7.045e-49	184.0	COG0671@1|root,COG0671@2|Bacteria,1GHH3@1117|Cyanobacteria,1HI2U@1150|Oscillatoriales	1117|Cyanobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PAP2
GDHHQS2_k127_5123217_6	1267533.KB906740_gene279	2.507e-20	106.0	COG3710@1|root,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
GDHHQS2_k127_5123217_3	234267.Acid_3680	2.15e-76	276.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5128324_5	1205680.CAKO01000038_gene1626	2.045e-80	273.0	28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,2JRUJ@204441|Rhodospirillales	204441|Rhodospirillales	E	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
GDHHQS2_k127_5128324_7	316056.RPC_2750	6.17e-34	141.0	2E3CR@1|root,32YC0@2|Bacteria,1N9Q9@1224|Proteobacteria,2UF5B@28211|Alphaproteobacteria,3JYQP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitrile hydratase beta subunit	MA20_29595	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
GDHHQS2_k127_5128324_8	937777.Deipe_2314	2.894e-33	139.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2062c	CobN-Mg_chel
GDHHQS2_k127_5128324_10	234267.Acid_5132	4.215e-25	110.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_5128324_13	1367847.JCM7686_2813	1.209e-13	78.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,2PY8U@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
GDHHQS2_k127_5128324_14	313628.LNTAR_21860	1.333e-07	63.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C,DUF1080,GSDH,HEAT_2
GDHHQS2_k127_5128324_6	118161.KB235922_gene5791	2.296e-38	156.0	COG0500@1|root,COG2226@2|Bacteria,1G1ZW@1117|Cyanobacteria,3VHXB@52604|Pleurocapsales	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_5128324_2	234267.Acid_1577	1.874e-113	373.0	COG1082@1|root,COG1082@2|Bacteria,3Y8GU@57723|Acidobacteria	2|Bacteria	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5128324_1	1267535.KB906767_gene1678	3.915e-122	397.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_5128324_0	756272.Plabr_3240	3.123e-135	443.0	COG3119@1|root,COG3386@1|root,COG3119@2|Bacteria,COG3386@2|Bacteria,2J1T1@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5128324_4	1267535.KB906767_gene2598	5.94e-81	276.0	COG0266@1|root,COG0266@2|Bacteria,3Y39U@57723|Acidobacteria,2JI11@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS2_k127_5128324_11	234267.Acid_6699	1.933e-24	107.0	COG2146@1|root,COG2146@2|Bacteria,3Y5NP@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Rieske 2Fe-2S	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GDHHQS2_k127_5128324_3	1340493.JNIF01000004_gene762	1.119e-90	308.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_5128324_9	234267.Acid_1618	6.089e-29	129.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GDHHQS2_k127_5128324_12	1267535.KB906767_gene1210	2.194e-24	108.0	COG4932@1|root,COG4932@2|Bacteria,3Y3KQ@57723|Acidobacteria,2JMAN@204432|Acidobacteriia	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5133164_2	234267.Acid_7326	9.999e-36	146.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS2_k127_5133164_0	756272.Plabr_4160	7.93e-154	501.0	COG3119@1|root,COG3119@2|Bacteria,2J25A@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5133164_5	388413.ALPR1_06385	0.0008386	48.0	2CD06@1|root,32XE0@2|Bacteria,4NSY1@976|Bacteroidetes,47RT2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5133164_1	1192124.LIG30_4709	1.852e-49	179.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2VV4U@28216|Betaproteobacteria,1K83F@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
GDHHQS2_k127_5133164_4	448385.sce1895	9.751e-13	69.0	2EEHD@1|root,338B8@2|Bacteria,1R0C1@1224|Proteobacteria,42W5S@68525|delta/epsilon subdivisions,2WRR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5134510_2	234267.Acid_1210	4.001e-06	54.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amino_oxidase,Ank,Ank_2,Ank_3,Ank_4,Ank_5,PSCyt1,Peptidase_C14,Prenyltrans,SQHop_cyclase_C
GDHHQS2_k127_5134510_1	234267.Acid_1210	5.375e-59	209.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amino_oxidase,Ank,Ank_2,Ank_3,Ank_4,Ank_5,PSCyt1,Peptidase_C14,Prenyltrans,SQHop_cyclase_C
GDHHQS2_k127_5134510_0	1267535.KB906767_gene1677	1.845e-133	438.0	COG3474@1|root,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02305,ko:K08738	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,HEAT_2
GDHHQS2_k127_513840_1	1340493.JNIF01000004_gene776	8.436e-51	186.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_513840_0	1340493.JNIF01000004_gene777	3.667e-270	846.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5140392_1	945713.IALB_2027	7.064e-08	64.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1,Sulfotransfer_3
GDHHQS2_k127_5140392_0	946483.Cenrod_0355	5.466e-112	376.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,4AEXG@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, family 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glycos_transf_2
GDHHQS2_k127_5143273_0	1340493.JNIF01000003_gene2798	1.209e-195	640.0	COG1344@1|root,COG1344@2|Bacteria,3Y4AW@57723|Acidobacteria	57723|Acidobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
GDHHQS2_k127_5143273_2	1121033.AUCF01000003_gene3412	1.014e-136	460.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2JPYC@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS2_k127_5143273_1	1380394.JADL01000014_gene269	2.852e-141	462.0	COG2227@1|root,COG2227@2|Bacteria,1MWY9@1224|Proteobacteria,2TU55@28211|Alphaproteobacteria,2JTPJ@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_14,Methyltransf_23
GDHHQS2_k127_5143273_3	1340493.JNIF01000003_gene2801	1.194e-108	367.0	COG1345@1|root,COG1345@2|Bacteria,3Y3NV@57723|Acidobacteria	57723|Acidobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
GDHHQS2_k127_5149951_2	215803.DB30_8307	2.198e-161	527.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
GDHHQS2_k127_5149951_9	1198114.AciX9_1275	9.089e-09	63.0	COG1629@1|root,COG1629@2|Bacteria,3Y9BI@57723|Acidobacteria,2JHTY@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5149951_3	234267.Acid_5869	9.591e-141	486.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5149951_4	1340493.JNIF01000004_gene737	1.85e-119	390.0	COG0329@1|root,COG0329@2|Bacteria,3Y7AU@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
GDHHQS2_k127_5149951_0	1340493.JNIF01000003_gene4451	7.048e-216	677.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria	2|Bacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_5149951_1	1267535.KB906767_gene3054	7.393e-214	673.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria,2JHSM@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS2_k127_5149951_6	1267535.KB906767_gene3055	8.694e-35	134.0	COG0228@1|root,COG0228@2|Bacteria,3Y56G@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS2_k127_5149951_8	234267.Acid_2571	2.497e-31	124.0	COG1837@1|root,COG1837@2|Bacteria,3Y5N5@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS2_k127_5149951_7	1267535.KB906767_gene3057	2.749e-32	135.0	COG0806@1|root,COG0806@2|Bacteria,3Y51G@57723|Acidobacteria	57723|Acidobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS2_k127_5149951_5	1267535.KB906767_gene3058	3.867e-96	320.0	COG0336@1|root,COG0336@2|Bacteria,3Y3CS@57723|Acidobacteria,2JHUJ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS2_k127_5150756_8	1267535.KB906767_gene2223	3.464e-12	70.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
GDHHQS2_k127_5150756_2	743525.TSC_c02960	3.968e-97	330.0	COG0438@1|root,COG0438@2|Bacteria,1WJN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5150756_4	404589.Anae109_1412	1.466e-50	186.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS2_k127_5150756_5	1340493.JNIF01000004_gene261	2.246e-44	167.0	COG2318@1|root,COG2318@2|Bacteria,3Y8BV@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS2_k127_5150756_6	1340493.JNIF01000003_gene2581	5.152e-35	140.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
GDHHQS2_k127_5150756_0	469383.Cwoe_1088	1.229e-198	626.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_5150756_1	1340493.JNIF01000004_gene521	6.177e-143	464.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_5150756_3	234267.Acid_2475	9.632e-75	261.0	COG0697@1|root,COG0697@2|Bacteria,3Y3CN@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_5150756_7	234267.Acid_2476	1.431e-33	135.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_515933_8	234267.Acid_7512	3.981e-53	196.0	COG1538@1|root,COG1538@2|Bacteria,3Y54R@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_515933_3	291112.PAU_00119	3.8e-108	370.0	COG2131@1|root,COG2131@2|Bacteria,1QDAH@1224|Proteobacteria,1RRDW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Deoxycytidylate deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GDHHQS2_k127_515933_0	1340493.JNIF01000003_gene2023	1.146e-214	691.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
GDHHQS2_k127_515933_4	234267.Acid_7785	1.559e-99	344.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	-	-	-	ko:K02461,ko:K02662	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilM_2,PilN,T2SSL
GDHHQS2_k127_515933_6	234267.Acid_7784	1.91e-72	259.0	COG3156@1|root,COG3156@2|Bacteria	2|Bacteria	U	protein secretion	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
GDHHQS2_k127_515933_10	234267.Acid_7782	6.177e-40	153.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	CP_1053	-	-	ko:K02456,ko:K02458,ko:K02459,ko:K10927	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GDHHQS2_k127_515933_9	234267.Acid_7780	2.24e-52	188.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspG	-	-	ko:K02246,ko:K02456,ko:K02458	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
GDHHQS2_k127_515933_1	1340493.JNIF01000003_gene2033	1.561e-174	559.0	COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
GDHHQS2_k127_515933_2	706587.Desti_3124	6.751e-145	476.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MQ93@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
GDHHQS2_k127_515933_5	234267.Acid_7775	1.495e-72	248.0	COG1595@1|root,COG1595@2|Bacteria,3Y7WY@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5167242_3	234267.Acid_2608	9.222e-62	221.0	COG1661@1|root,COG1661@2|Bacteria	2|Bacteria	O	DNA-binding protein with PD1-like DNA-binding motif	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296,Glutaredoxin
GDHHQS2_k127_5167242_4	35754.JNYJ01000023_gene8308	4.241e-32	131.0	COG1506@1|root,COG1506@2|Bacteria,2H90U@201174|Actinobacteria,4D8UC@85008|Micromonosporales	201174|Actinobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_5167242_2	234267.Acid_0995	2.288e-64	231.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5167242_0	1340493.JNIF01000003_gene1440	0.0	1056.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
GDHHQS2_k127_5167242_1	234267.Acid_0264	7.997e-125	415.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
GDHHQS2_k127_5177184_1	1095769.CAHF01000022_gene253	3.531e-117	400.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_5177184_3	234267.Acid_6305	4.056e-94	325.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_09690	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5177184_0	1340493.JNIF01000003_gene2866	7.237e-204	640.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5177184_4	1173028.ANKO01000044_gene791	1.338e-52	201.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47,GNAT_acetyltran
GDHHQS2_k127_5177184_5	234267.Acid_3653	1.557e-12	79.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
GDHHQS2_k127_5177591_1	234267.Acid_5749	1.296e-40	163.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5177591_0	234267.Acid_5749	8.737e-170	563.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5177591_2	1379270.AUXF01000002_gene1760	9.124e-35	134.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZU9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_5177591_3	1379270.AUXF01000002_gene1760	8.168e-32	125.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZU9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_518258_0	1340493.JNIF01000004_gene564	4.861e-316	1004.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_518258_7	1330700.JQNC01000001_gene2250	0.0006171	45.0	COG2026@1|root,COG2026@2|Bacteria,1WN9J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_518258_5	1299327.I546_1392	5.964e-05	49.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
GDHHQS2_k127_518258_1	1340493.JNIF01000004_gene1055	2.585e-193	612.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_518258_2	234267.Acid_7352	4.395e-132	437.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07709,ko:K07710	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_10,PAS_4
GDHHQS2_k127_518258_3	1340493.JNIF01000004_gene1058	4.16e-74	269.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,Peptidase_S74
GDHHQS2_k127_518258_6	160860.XP_007352766.1	0.0004395	45.0	KOG0266@1|root,KOG0266@2759|Eukaryota,38B6D@33154|Opisthokonta,3NZ4C@4751|Fungi,3V464@5204|Basidiomycota,224XH@155619|Agaricomycetes,3H0W7@355688|Agaricomycetes incertae sedis	4751|Fungi	U	WD40 repeat-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,C2,NACHT,WD40
GDHHQS2_k127_5187202_0	926569.ANT_16180	3.241e-90	305.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS2_k127_5187202_3	266265.Bxe_B0307	4.364e-07	58.0	COG0834@1|root,COG3258@1|root,COG0834@2|Bacteria,COG3258@2|Bacteria,1MVR7@1224|Proteobacteria,2WG58@28216|Betaproteobacteria,1KI9X@119060|Burkholderiaceae	28216|Betaproteobacteria	CET	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	Cytochrome_CBB3,SBP_bac_3
GDHHQS2_k127_5187202_1	861299.J421_1105	2.61e-20	96.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS2_k127_5187202_2	1380347.JNII01000006_gene1196	6.351e-09	66.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4ERGQ@85013|Frankiales	201174|Actinobacteria	M	PFAM glycosyl transferase, family 51	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
GDHHQS2_k127_5187202_4	880073.Calab_2440	0.0002798	45.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_5195079_2	292415.Tbd_0089	5.945e-06	49.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS2_k127_5195079_1	1120965.AUBV01000004_gene719	1.345e-58	226.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,47NMX@768503|Cytophagia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
GDHHQS2_k127_5195079_0	234267.Acid_4566	1.076e-162	532.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16,TPR_4
GDHHQS2_k127_519534_3	1340493.JNIF01000003_gene4600	7.414e-46	174.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_519534_5	56107.Cylst_1612	4.824e-18	86.0	COG4637@1|root,COG4637@2|Bacteria,1G3KQ@1117|Cyanobacteria,1HP4S@1161|Nostocales	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
GDHHQS2_k127_519534_2	1254432.SCE1572_17850	1.11e-54	208.0	COG2960@1|root,COG2960@2|Bacteria,1R494@1224|Proteobacteria,43CJP@68525|delta/epsilon subdivisions,2X7U1@28221|Deltaproteobacteria,2YXZK@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_519534_1	1192034.CAP_9004	1.812e-93	332.0	COG5297@1|root,COG5297@2|Bacteria,1PG5N@1224|Proteobacteria,439EZ@68525|delta/epsilon subdivisions,2X4Q8@28221|Deltaproteobacteria,2YZDX@29|Myxococcales	28221|Deltaproteobacteria	G	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_519534_6	1244869.H261_14725	7.518e-15	74.0	COG3514@1|root,COG3514@2|Bacteria,1N7KA@1224|Proteobacteria,2UGW1@28211|Alphaproteobacteria,2JUGY@204441|Rhodospirillales	204441|Rhodospirillales	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
GDHHQS2_k127_519534_4	1173029.JH980292_gene1682	5.749e-23	102.0	COG3440@1|root,COG3440@2|Bacteria,1G680@1117|Cyanobacteria,1HBA3@1150|Oscillatoriales	1117|Cyanobacteria	L	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
GDHHQS2_k127_519534_0	204669.Acid345_4118	4.406e-160	535.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_5204565_1	234267.Acid_7400	6.811e-28	119.0	COG2318@1|root,COG2318@2|Bacteria,3Y8J8@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_5204565_0	234267.Acid_2975	7.088e-232	751.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5206373_13	234267.Acid_6300	2e-07	52.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25,Methyltransf_31,TehB
GDHHQS2_k127_5206373_4	1267535.KB906767_gene4620	3.399e-85	292.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_5206373_14	1307436.PBF_15649	0.0005673	46.0	COG0346@1|root,COG0346@2|Bacteria,1VXII@1239|Firmicutes,4HX0Q@91061|Bacilli,1ZIMX@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_5206373_7	1192868.CAIU01000027_gene3703	2.178e-51	187.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,43R40@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_5206373_1	504832.OCAR_7507	1.875e-175	582.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JRND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_5206373_9	1185876.BN8_02276	3.672e-34	138.0	2BW4G@1|root,2ZAQH@2|Bacteria,4NRKB@976|Bacteroidetes,47QKV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
GDHHQS2_k127_5206373_0	1207063.P24_05304	3.101e-185	584.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2U0W7@28211|Alphaproteobacteria,2JW88@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5206373_10	1340493.JNIF01000003_gene4150	3.483e-24	118.0	COG1470@1|root,COG4625@1|root,COG1470@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
GDHHQS2_k127_5206373_3	234267.Acid_0027	3.032e-107	355.0	COG1082@1|root,COG1082@2|Bacteria,3Y6EB@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_5206373_2	234267.Acid_7871	5.261e-127	424.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria	57723|Acidobacteria	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS2_k127_5206373_12	1340493.JNIF01000003_gene4009	1.848e-07	56.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K07577,ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N,Lactamase_B_2,RMMBL
GDHHQS2_k127_5206373_11	1340493.JNIF01000003_gene4009	8.191e-21	94.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K07577,ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N,Lactamase_B_2,RMMBL
GDHHQS2_k127_5206373_5	1303518.CCALI_00300	1.444e-79	278.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GDHHQS2_k127_5206373_8	1340493.JNIF01000003_gene2739	1.021e-39	152.0	COG4818@1|root,COG4818@2|Bacteria,3Y8T8@57723|Acidobacteria	57723|Acidobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5206373_6	457429.ABJI02000040_gene3857	5.681e-77	268.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
GDHHQS2_k127_5211497_2	861299.J421_4147	2.651e-05	58.0	COG2319@1|root,COG4409@1|root,COG2319@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,F5_F8_type_C,TIR_2,WD40
GDHHQS2_k127_5211497_3	1256908.HMPREF0373_02696	3.493e-05	57.0	COG4870@1|root,COG5434@1|root,COG4870@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3,Peptidase_C1
GDHHQS2_k127_5211497_0	1340493.JNIF01000003_gene1774	1.472e-184	598.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
GDHHQS2_k127_5211497_1	234267.Acid_0229	4.011e-70	258.0	COG2890@1|root,COG2890@2|Bacteria,3Y8Q3@57723|Acidobacteria	57723|Acidobacteria	J	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5215523_0	1267535.KB906767_gene942	1.669e-76	279.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5216402_1	449447.MAE_39720	4.726e-06	55.0	COG1403@1|root,COG1403@2|Bacteria,1G76A@1117|Cyanobacteria	1117|Cyanobacteria	V	TIGRFAM TIGR02646 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5216402_0	234267.Acid_7841	5.749e-284	902.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5224617_1	234267.Acid_6540	1.212e-239	747.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5224617_0	234267.Acid_6541	0.0	1255.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5224617_2	595460.RRSWK_01499	1.449e-14	79.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5224617_4	324925.Ppha_2348	0.0005664	51.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GDHHQS2_k127_5224617_3	331869.BAL199_01174	3.193e-09	68.0	29ISC@1|root,2Z7VE@2|Bacteria,1MWUK@1224|Proteobacteria,2TTFU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
GDHHQS2_k127_5226746_2	234267.Acid_7476	3.969e-93	311.0	COG0381@1|root,COG0381@2|Bacteria,3Y50B@57723|Acidobacteria	57723|Acidobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS2_k127_5226746_0	1340493.JNIF01000003_gene2953	1.072e-190	604.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_5226746_3	234267.Acid_3123	2.225e-36	151.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_5226746_1	639030.JHVA01000001_gene3793	9.593e-105	361.0	COG4993@1|root,COG4993@2|Bacteria,3Y708@57723|Acidobacteria,2JMES@204432|Acidobacteriia	204432|Acidobacteriia	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_52282_1	234267.Acid_6855	7.182e-220	692.0	COG3119@1|root,COG3119@2|Bacteria,3Y7MP@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_52282_7	234267.Acid_2277	6.112e-86	291.0	COG1136@1|root,COG1136@2|Bacteria,3Y412@57723|Acidobacteria	57723|Acidobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GDHHQS2_k127_52282_0	1340493.JNIF01000003_gene1805	0.0	1416.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS2_k127_52282_5	671143.DAMO_1779	9.562e-103	352.0	COG0784@1|root,COG2199@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_52282_4	1267535.KB906767_gene2340	3.474e-122	404.0	COG0470@1|root,COG0470@2|Bacteria,3Y6V7@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS2_k127_52282_11	765914.ThisiDRAFT_0043	6.627e-07	60.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,1WVWK@135613|Chromatiales	135613|Chromatiales	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_52282_2	234267.Acid_0024	2.034e-166	555.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_52282_8	1379698.RBG1_1C00001G0781	2.008e-44	168.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
GDHHQS2_k127_52282_3	1379698.RBG1_1C00001G0780	1.092e-133	434.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
GDHHQS2_k127_52282_6	671143.DAMO_0822	3.611e-100	341.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GDHHQS2_k127_52282_10	1125863.JAFN01000001_gene1841	1.857e-31	137.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
GDHHQS2_k127_52282_12	330214.NIDE3888	9.84e-05	52.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
GDHHQS2_k127_52282_9	234267.Acid_5749	1.244e-32	132.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5234908_10	234267.Acid_2671	2.871e-22	102.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,3Y7VX@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
GDHHQS2_k127_5234908_7	697303.Thewi_2114	1.696e-65	231.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS2_k127_5234908_6	264732.Moth_2102	3.438e-106	355.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS2_k127_5234908_8	1209984.BN978_03698	1.014e-40	159.0	COG2186@1|root,COG2186@2|Bacteria,2I90D@201174|Actinobacteria,236Z8@1762|Mycobacteriaceae	201174|Actinobacteria	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_5234908_5	258594.RPA1579	4.74e-110	369.0	COG1804@1|root,COG1804@2|Bacteria,1MWPB@1224|Proteobacteria,2U1YE@28211|Alphaproteobacteria,3JS2K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	MA20_04610	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GDHHQS2_k127_5234908_4	5762.XP_002670100.1	6.411e-121	398.0	COG0183@1|root,KOG1391@2759|Eukaryota	2759|Eukaryota	I	negative regulation of mitochondrial membrane permeability involved in apoptotic process	-	-	2.3.1.16	ko:K07508	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_5234908_0	234267.Acid_0041	2.934e-215	687.0	COG4122@1|root,COG4122@2|Bacteria,3Y33U@57723|Acidobacteria	57723|Acidobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5234908_2	1123242.JH636434_gene5367	2.403e-133	447.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5234908_3	401053.AciPR4_1061	1.65e-126	409.0	COG1028@1|root,COG1028@2|Bacteria,3Y67C@57723|Acidobacteria,2JM0Y@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_5234908_1	1340493.JNIF01000003_gene1399	1.021e-157	506.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_5234908_9	1267534.KB906756_gene541	5.716e-27	115.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS2_k127_5237653_1	1267535.KB906767_gene3739	3.106e-51	181.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
GDHHQS2_k127_5237653_0	886293.Sinac_0326	6.014e-52	204.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_5239524_2	324602.Caur_2138	6.552e-21	96.0	COG3880@1|root,COG3880@2|Bacteria,2G79C@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
GDHHQS2_k127_5239524_0	1123242.JH636434_gene5252	6.401e-68	243.0	2BT55@1|root,32N9W@2|Bacteria,2J2NS@203682|Planctomycetes	203682|Planctomycetes	S	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5239524_3	861299.J421_2199	0.0003881	44.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_2199|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5239524_1	497964.CfE428DRAFT_1132	1.312e-44	164.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
GDHHQS2_k127_5241637_3	314230.DSM3645_21082	5.187e-38	152.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_5241637_2	1396418.BATQ01000138_gene3923	4.275e-180	572.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_5241637_1	1396418.BATQ01000138_gene3922	9.86e-318	994.0	COG2010@1|root,COG2010@2|Bacteria,46UH6@74201|Verrucomicrobia,2IWNW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_5241637_0	1267535.KB906767_gene3159	0.0	1709.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS2_k127_5245003_2	234267.Acid_1391	3.743e-42	158.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CTP_transf_3,HNH_4,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_5245003_1	234267.Acid_1392	3.34e-64	231.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	3.6.3.38,3.6.3.40	ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,LysM,Wzt_C
GDHHQS2_k127_5247348_11	240016.ABIZ01000001_gene771	1.879e-26	112.0	28IED@1|root,2Z8GE@2|Bacteria,46VP7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
GDHHQS2_k127_5247348_7	595460.RRSWK_04509	7.66e-74	263.0	COG0673@1|root,COG0673@2|Bacteria,2J321@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_5247348_4	1267535.KB906767_gene2192	6.666e-103	340.0	COG1028@1|root,COG1028@2|Bacteria,3Y2JR@57723|Acidobacteria,2JJ3M@204432|Acidobacteriia	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_5247348_13	1040987.AZUY01000024_gene5604	0.0005033	50.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2U93G@28211|Alphaproteobacteria,43K75@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
GDHHQS2_k127_5247348_2	234267.Acid_1458	9.025e-139	452.0	COG2017@1|root,COG2017@2|Bacteria,3Y3D2@57723|Acidobacteria	57723|Acidobacteria	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
GDHHQS2_k127_5247348_1	1340493.JNIF01000004_gene859	1.054e-162	527.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_5247348_14	290397.Adeh_2379	0.0005362	51.0	COG5662@1|root,COG5662@2|Bacteria,1PC36@1224|Proteobacteria,4387X@68525|delta/epsilon subdivisions,2X3HP@28221|Deltaproteobacteria,2YW5D@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_5247348_6	234267.Acid_0293	1.044e-75	268.0	COG0251@1|root,COG0251@2|Bacteria,3Y810@57723|Acidobacteria	57723|Acidobacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5247348_3	344747.PM8797T_14594	3.748e-137	461.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5247348_9	330214.NIDE1891	4.097e-40	171.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
GDHHQS2_k127_5247348_5	1340493.JNIF01000003_gene2850	6.213e-91	313.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5247348_8	536227.CcarbDRAFT_0601	1.899e-57	220.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,36DRS@31979|Clostridiaceae	186801|Clostridia	M	Peptidase, S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_5247348_10	1267535.KB906767_gene2621	1.716e-36	147.0	2985T@1|root,2ZVBP@2|Bacteria,3Y971@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5247348_0	1340493.JNIF01000003_gene1756	1.141e-173	565.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_5247348_12	1340493.JNIF01000003_gene1755	1.786e-20	91.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5252692_0	234267.Acid_1149	1.411e-261	814.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y639@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
GDHHQS2_k127_5257634_0	1123242.JH636435_gene2066	2.032e-65	244.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_5257634_1	1123242.JH636435_gene2066	6.401e-25	113.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_5257666_0	391038.Bphy_5030	1.528e-57	219.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,2VMKQ@28216|Betaproteobacteria,1K5CU@119060|Burkholderiaceae	28216|Betaproteobacteria	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_5265195_6	1379698.RBG1_1C00001G0607	7.182e-22	104.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS2_k127_5265195_5	391625.PPSIR1_16130	4.953e-25	108.0	COG3039@1|root,COG3039@2|Bacteria,1R70H@1224|Proteobacteria,42Y58@68525|delta/epsilon subdivisions,2WTVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
GDHHQS2_k127_5265195_4	1267535.KB906767_gene1985	5.498e-44	165.0	COG0640@1|root,COG0640@2|Bacteria,3Y5ZP@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_5265195_2	1304275.C41B8_09816	1.824e-128	416.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,1RQQ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	hsdl2	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
GDHHQS2_k127_5265195_0	234267.Acid_1911	3.302e-160	518.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_5265195_8	483218.BACPEC_02937	1.089e-05	57.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,26BU0@186813|unclassified Clostridiales	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS2_k127_5265195_3	234267.Acid_1909	7.586e-79	273.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
GDHHQS2_k127_5265195_1	1340493.JNIF01000003_gene3916	2.689e-149	481.0	COG2006@1|root,COG2006@2|Bacteria,3Y6M1@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS2_k127_5272630_2	1313265.JNIE01000005_gene358	4.777e-11	63.0	COG3255@1|root,COG3255@2|Bacteria,2G5AQ@200783|Aquificae	200783|Aquificae	I	PFAM Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GDHHQS2_k127_5272630_0	582744.Msip34_2161	1.179e-130	432.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,2KKSH@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
GDHHQS2_k127_5272630_1	870187.Thini_2258	1.092e-14	74.0	COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,1S4I3@1236|Gammaproteobacteria,462TD@72273|Thiotrichales	72273|Thiotrichales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
GDHHQS2_k127_5281294_2	1123242.JH636435_gene1206	1.811e-56	200.0	COG3291@1|root,COG3291@2|Bacteria,2J3CN@203682|Planctomycetes	203682|Planctomycetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5281294_0	1340493.JNIF01000004_gene823	1.016e-155	496.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GDHHQS2_k127_5281294_1	1541065.JRFE01000058_gene5490	8.198e-140	458.0	COG2132@1|root,COG2132@2|Bacteria,1G2BC@1117|Cyanobacteria,3VIIQ@52604|Pleurocapsales	1117|Cyanobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GDHHQS2_k127_5281294_3	1123073.KB899245_gene23	3.565e-35	152.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_528800_1	234267.Acid_7087	2.055e-97	327.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
GDHHQS2_k127_528800_0	234267.Acid_0844	1.374e-116	381.0	COG0673@1|root,COG0673@2|Bacteria,3Y6RA@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
GDHHQS2_k127_5288281_1	1380346.JNIH01000022_gene3891	1.294e-21	108.0	COG3170@1|root,COG3209@1|root,COG3210@1|root,COG3170@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Tox-HNH-EHHH
GDHHQS2_k127_5288281_0	1183438.GKIL_3544	2.934e-31	127.0	COG1716@1|root,COG1716@2|Bacteria,1G9NG@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
GDHHQS2_k127_5288495_1	391600.ABRU01000042_gene2465	5.269e-12	70.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TY7Z@28211|Alphaproteobacteria,2KJVR@204458|Caulobacterales	204458|Caulobacterales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_5288495_0	234267.Acid_1210	2.429e-84	302.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amino_oxidase,Ank,Ank_2,Ank_3,Ank_4,Ank_5,PSCyt1,Peptidase_C14,Prenyltrans,SQHop_cyclase_C
GDHHQS2_k127_5290085_3	314230.DSM3645_28727	3.013e-44	179.0	COG0613@1|root,COG0613@2|Bacteria,2IZFJ@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5290085_6	1267535.KB906767_gene1312	1.179e-05	52.0	297GA@1|root,2ZUPK@2|Bacteria,3Y8WK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5290085_1	1340493.JNIF01000003_gene3853	2.527e-146	469.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS2_k127_5290085_5	452637.Oter_0807	8.309e-15	80.0	COG2010@1|root,COG2010@2|Bacteria,46TBB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS2_k127_5290085_2	234267.Acid_7234	1.906e-120	397.0	COG0457@1|root,COG0457@2|Bacteria,3Y5ID@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5290085_4	1382359.JIAL01000001_gene1881	7.157e-42	173.0	COG1188@1|root,COG1188@2|Bacteria,3Y5C6@57723|Acidobacteria,2JJNN@204432|Acidobacteriia	204432|Acidobacteriia	J	RNA-binding S4 domain protein	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
GDHHQS2_k127_5290085_0	1267535.KB906767_gene2350	4.768e-280	876.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_5301942_1	234267.Acid_0041	2.6e-61	216.0	COG4122@1|root,COG4122@2|Bacteria,3Y33U@57723|Acidobacteria	57723|Acidobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5301942_0	795666.MW7_1725	5.218e-79	284.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNBG@28216|Betaproteobacteria,1K297@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5301942_2	644968.DFW101_2543	1.357e-58	218.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria,2MC5V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS2_k127_530204_2	518766.Rmar_0288	3.832e-26	113.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4NI98@976|Bacteroidetes	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS2_k127_530204_0	1122605.KB893637_gene3269	6.923e-101	360.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_530204_4	401053.AciPR4_2718	3.302e-20	98.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
GDHHQS2_k127_530204_1	522306.CAP2UW1_1195	7.817e-92	318.0	COG1067@1|root,COG1067@2|Bacteria,1NDS0@1224|Proteobacteria	1224|Proteobacteria	O	ATP-dependent peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5302288_0	861299.J421_0887	8.523e-192	619.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5302288_1	204669.Acid345_0011	6.246e-100	333.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
GDHHQS2_k127_5304922_0	861299.J421_2921	4.496e-49	183.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS2_k127_5304922_1	1379270.AUXF01000005_gene739	3.992e-23	111.0	COG2010@1|root,COG2010@2|Bacteria,1ZT9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5304922_2	1535422.ND16A_3834	1.396e-18	91.0	COG1999@1|root,COG2010@1|root,COG1999@2|Bacteria,COG2010@2|Bacteria,1R725@1224|Proteobacteria,1S1UW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	SCO1 SenC	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,SCO1-SenC
GDHHQS2_k127_5304922_3	580332.Slit_0264	8.964e-09	67.0	2AFYG@1|root,31628@2|Bacteria,1PWQT@1224|Proteobacteria,2WC9D@28216|Betaproteobacteria,44VMT@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5306086_1	395495.Lcho_0045	1.694e-90	310.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
GDHHQS2_k127_5306086_2	395495.Lcho_0046	5.011e-36	141.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VVWD@28216|Betaproteobacteria,1KPCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_5306086_0	1385519.N801_15195	1.734e-96	325.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_5312509_6	234267.Acid_0006	8.467e-11	70.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,3Y5CC@57723|Acidobacteria	57723|Acidobacteria	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
GDHHQS2_k127_5312509_5	632335.Calkr_2472	6.415e-23	109.0	COG2520@1|root,COG2520@2|Bacteria,1VNBP@1239|Firmicutes	1239|Firmicutes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_5312509_3	1267535.KB906767_gene1058	2.66e-47	177.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
GDHHQS2_k127_5312509_1	1340493.JNIF01000004_gene501	3.312e-100	329.0	COG1435@1|root,COG1435@2|Bacteria,3Y4XG@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GDHHQS2_k127_5312509_0	345341.KUTG_09562	7.066e-217	685.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZ4K@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_5312509_2	530564.Psta_3944	7.994e-84	287.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_5312509_4	204669.Acid345_0294	1.614e-40	155.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_5316041_1	663610.JQKO01000003_gene1473	4.237e-40	153.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UBP8@28211|Alphaproteobacteria,3NBJ7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS2_k127_5316041_0	234267.Acid_7008	2.29e-181	573.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5322137_1	861299.J421_2134	7.722e-28	120.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	socC	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5322137_0	234267.Acid_5013	1.78e-202	639.0	COG2192@1|root,COG2192@2|Bacteria,3Y6AX@57723|Acidobacteria	57723|Acidobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS2_k127_532688_3	234267.Acid_1568	1.311e-10	63.0	COG3391@1|root,COG3391@2|Bacteria,3Y99Z@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIG
GDHHQS2_k127_532688_1	234267.Acid_1569	1.316e-47	175.0	COG1267@1|root,COG1267@2|Bacteria,3Y4T1@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
GDHHQS2_k127_532688_2	204669.Acid345_2143	8.38e-12	68.0	COG3024@1|root,COG3024@2|Bacteria,3Y5P1@57723|Acidobacteria,2JK03@204432|Acidobacteriia	204432|Acidobacteriia	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	-	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
GDHHQS2_k127_532688_0	278963.ATWD01000001_gene1650	8.391e-142	462.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS2_k127_5335009_1	1168289.AJKI01000041_gene3249	3.182e-79	274.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,3XINE@558415|Marinilabiliaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_5335009_0	497964.CfE428DRAFT_4769	1.89e-131	427.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5335009_2	1267533.KB906734_gene4416	0.0002368	47.0	COG4099@1|root,COG4099@2|Bacteria,3Y5YX@57723|Acidobacteria,2JMZ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_5336453_3	886293.Sinac_0335	3.55e-05	51.0	COG3387@1|root,COG3387@2|Bacteria,2J4DB@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5336453_0	1340493.JNIF01000004_gene603	4.633e-166	536.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7
GDHHQS2_k127_5336453_1	1340493.JNIF01000004_gene885	6.865e-120	388.0	COG0745@1|root,COG0745@2|Bacteria	1340493.JNIF01000004_gene885|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5336453_2	497964.CfE428DRAFT_5247	2.422e-10	68.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_5337292_3	1267535.KB906767_gene3478	3.202e-26	111.0	COG1847@1|root,COG1847@2|Bacteria,3Y52C@57723|Acidobacteria,2JJF9@204432|Acidobacteriia	204432|Acidobacteriia	S	R3H domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	R3H
GDHHQS2_k127_5337292_0	234267.Acid_1088	1.005e-181	578.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria	57723|Acidobacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS2_k127_5337292_2	1267535.KB906767_gene4647	1.065e-49	189.0	COG4449@1|root,COG4449@2|Bacteria,3Y84G@57723|Acidobacteria	57723|Acidobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_5337292_1	1340493.JNIF01000004_gene505	3.483e-173	550.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GDHHQS2_k127_5337292_4	1340493.JNIF01000003_gene3788	3.455e-08	59.0	COG1344@1|root,COG1344@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgL	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
GDHHQS2_k127_5350278_1	1340493.JNIF01000004_gene528	9.329e-124	406.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,HlyD_3,PSCyt1,PSCyt2,PSD1,RNA_pol_Rpb1_5
GDHHQS2_k127_5350278_0	1340493.JNIF01000004_gene527	4.453e-182	582.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5350278_3	1340493.JNIF01000004_gene464	1.057e-39	160.0	COG3395@1|root,COG3395@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
GDHHQS2_k127_5350278_2	1267535.KB906767_gene1817	7.815e-118	384.0	COG1995@1|root,COG1995@2|Bacteria,3Y37Q@57723|Acidobacteria	57723|Acidobacteria	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
GDHHQS2_k127_5357268_4	234267.Acid_2796	5.39e-19	94.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_5357268_0	234267.Acid_2799	7.464e-141	458.0	COG1181@1|root,COG1181@2|Bacteria,3Y3HW@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS2_k127_5357268_1	234267.Acid_2800	2.565e-131	424.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria	57723|Acidobacteria	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS2_k127_5357268_3	234267.Acid_6765	2.727e-27	116.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS2_k127_5357268_2	1028801.RG1141_PA05170	3.057e-43	160.0	COG2337@1|root,COG2337@2|Bacteria,1RH4Z@1224|Proteobacteria,2UAHY@28211|Alphaproteobacteria,4BHX4@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	pemK	-	-	ko:K18841	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_5368306_3	1210884.HG799463_gene10170	1.135e-155	509.0	COG2271@1|root,COG2271@2|Bacteria,2IXXA@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5368306_5	1123242.JH636435_gene2135	7.513e-117	383.0	COG1028@1|root,COG1028@2|Bacteria,2J2DG@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_5368306_1	1210884.HG799463_gene10171	2.362e-296	923.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2IYRX@203682|Planctomycetes	203682|Planctomycetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_5368306_8	1210884.HG799463_gene10172	1.061e-95	325.0	COG0508@1|root,COG0508@2|Bacteria,2IXCU@203682|Planctomycetes	203682|Planctomycetes	C	e3 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_5368306_11	671143.DAMO_2322	7.519e-11	67.0	COG2865@1|root,COG2865@2|Bacteria,2NRI7@2323|unclassified Bacteria	2|Bacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,DUF4365,HATPase_c_4
GDHHQS2_k127_5368306_4	1267535.KB906767_gene3133	7.77e-138	477.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5368306_0	1340493.JNIF01000003_gene4293	0.0	1247.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5368306_6	234267.Acid_2874	5.054e-104	349.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS2_k127_5368306_10	1340493.JNIF01000003_gene2260	2.823e-45	172.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	CBM_6,Cadherin,DUF1929,HemolysinCabind,Malectin,Metallophos,PA14,Pur_ac_phosph_N
GDHHQS2_k127_5368306_9	452637.Oter_1690	1.856e-87	308.0	COG1680@1|root,COG1680@2|Bacteria,46V0A@74201|Verrucomicrobia,3K85Q@414999|Opitutae	414999|Opitutae	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_5368306_7	100226.SCO3475	4.431e-97	332.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6,4.2.1.8	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	M00061,M00552	R03033,R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5368306_2	1267535.KB906767_gene4118	1.304e-157	509.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
GDHHQS2_k127_5368306_12	1510531.JQJJ01000012_gene1764	2.611e-10	69.0	COG0346@1|root,COG0346@2|Bacteria,1RB65@1224|Proteobacteria,2U7DP@28211|Alphaproteobacteria,3JYA1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_35640	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_5370335_2	1267535.KB906767_gene1304	2.733e-68	237.0	COG1131@1|root,COG1131@2|Bacteria,3Y394@57723|Acidobacteria,2JINE@204432|Acidobacteriia	204432|Acidobacteriia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_5370335_1	1267535.KB906767_gene1239	1.53e-145	471.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
GDHHQS2_k127_5370335_0	234267.Acid_7399	1.759e-222	704.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS2_k127_5370335_5	1340493.JNIF01000003_gene3012	8.013e-21	98.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria	57723|Acidobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS2_k127_5370335_3	1123073.KB899245_gene23	1.162e-41	179.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_5370335_6	234267.Acid_0064	6.821e-18	100.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc,PEGA
GDHHQS2_k127_5370335_4	1340493.JNIF01000003_gene2911	1.847e-32	149.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_5371002_3	234267.Acid_1476	1.637e-16	82.0	COG0013@1|root,COG0013@2|Bacteria,3Y4AR@57723|Acidobacteria	57723|Acidobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS2_k127_5371002_4	234267.Acid_5372	1.18e-14	81.0	COG0745@1|root,COG0745@2|Bacteria,3Y53N@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_5371002_0	1340493.JNIF01000003_gene2092	6.842e-311	959.0	COG2303@1|root,COG2303@2|Bacteria,3Y41Y@57723|Acidobacteria	2|Bacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_5371002_1	450851.PHZ_c1163	1.304e-94	332.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWFB@28211|Alphaproteobacteria,2KFH9@204458|Caulobacterales	204458|Caulobacterales	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
GDHHQS2_k127_5372442_0	1185876.BN8_01991	6.676e-54	196.0	COG1434@1|root,COG1434@2|Bacteria,4NI3S@976|Bacteroidetes,47NUZ@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_5372442_2	639030.JHVA01000001_gene3707	9.039e-09	64.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5372442_1	1267535.KB906767_gene942	6.335e-31	134.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5374298_0	1122604.JONR01000006_gene2702	1.37e-33	141.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1X78Y@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_5375759_3	1123242.JH636437_gene6095	2.231e-31	125.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GDHHQS2_k127_5375759_0	234267.Acid_6696	1.781e-102	344.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GX@57723|Acidobacteria	57723|Acidobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_5375759_1	234267.Acid_7948	2.131e-46	180.0	2E6AH@1|root,330YD@2|Bacteria,3Y8MQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5375759_2	234267.Acid_5431	2.563e-45	169.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5385767_0	1123487.KB892834_gene2883	5.683e-117	381.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,2VH1P@28216|Betaproteobacteria,2KUKG@206389|Rhodocyclales	206389|Rhodocyclales	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS2_k127_5385767_1	313628.LNTAR_22304	2.436e-89	311.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5395716_2	1267535.KB906767_gene1045	5.482e-128	409.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_5395716_9	1170562.Cal6303_0444	5.735e-08	55.0	COG1309@1|root,COG1309@2|Bacteria,1G5HM@1117|Cyanobacteria,1HMGJ@1161|Nostocales	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_C_13,TetR_C_6,TetR_N
GDHHQS2_k127_5395716_7	1380394.JADL01000002_gene1665	2.09e-12	73.0	COG0627@1|root,COG0627@2|Bacteria,1R4M6@1224|Proteobacteria,2U4X7@28211|Alphaproteobacteria,2JXF4@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS2_k127_5395716_1	234267.Acid_2635	6.707e-200	632.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria	2|Bacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_5395716_4	234267.Acid_4321	5.575e-81	293.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_5395716_3	234267.Acid_4320	1.431e-84	289.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_5395716_10	886293.Sinac_4414	2.035e-06	60.0	COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SBP_bac_10
GDHHQS2_k127_5395716_0	1267535.KB906767_gene4757	2.888e-212	666.0	COG2115@1|root,COG2115@2|Bacteria,3Y841@57723|Acidobacteria,2JNHR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the xylose isomerase family	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_5395716_11	107635.AZUO01000001_gene2472	0.0002582	46.0	2DQNW@1|root,337UD@2|Bacteria,1QW56@1224|Proteobacteria,2TWMY@28211|Alphaproteobacteria,370ND@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_5395716_6	107636.JQNK01000009_gene1484	2.548e-32	132.0	COG1487@1|root,COG1487@2|Bacteria,1RD5N@1224|Proteobacteria,2U73N@28211|Alphaproteobacteria,36ZYM@31993|Methylocystaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS2_k127_5395716_8	1297570.MESS4_640150	1.717e-10	63.0	COG1487@1|root,COG1487@2|Bacteria,1RD5N@1224|Proteobacteria,2U73N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS2_k127_5395716_5	661478.OP10G_1956	6.307e-37	151.0	COG0405@1|root,COG0405@2|Bacteria	2|Bacteria	E	Gamma-glutamyltransferase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_5400666_0	1267534.KB906757_gene956	3.544e-144	483.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Trans_reg_C,WD40
GDHHQS2_k127_5400666_1	234267.Acid_5940	1.31e-41	155.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5416168_1	69395.JQLZ01000015_gene4098	4.255e-56	207.0	arCOG06613@1|root,2Z7VT@2|Bacteria,1MVIU@1224|Proteobacteria,2TV9A@28211|Alphaproteobacteria,2KHK7@204458|Caulobacterales	204458|Caulobacterales	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
GDHHQS2_k127_5416168_2	246197.MXAN_3603	2.579e-35	148.0	arCOG12551@1|root,2Z9WJ@2|Bacteria,1R6MT@1224|Proteobacteria,42VPP@68525|delta/epsilon subdivisions,2WVS7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative  PD-(D/E)XK family member, (DUF4420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4420
GDHHQS2_k127_5416168_0	1509405.GV67_00115	2.7e-306	964.0	COG1100@1|root,COG1100@2|Bacteria,1MWZW@1224|Proteobacteria,2TTBM@28211|Alphaproteobacteria,4BCX5@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
GDHHQS2_k127_5420697_1	1049564.TevJSym_bb00040	1.791e-124	406.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS2_k127_5420697_0	1049564.TevJSym_bb00050	5.941e-246	785.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS2_k127_5420697_9	756272.Plabr_4631	7.529e-07	52.0	COG2010@1|root,COG2010@2|Bacteria,2J21K@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5420697_2	886293.Sinac_5029	1.048e-102	339.0	COG1878@1|root,COG1878@2|Bacteria,2IZXG@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS2_k127_5420697_6	1229780.BN381_70076	2.686e-14	87.0	COG1404@1|root,COG1404@2|Bacteria,2H8Y3@201174|Actinobacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,Big_3_2,Flg_new,PKD,RCC1,RCC1_2,SLH
GDHHQS2_k127_5420697_8	316273.XCV4444	3.398e-10	73.0	COG0739@1|root,COG4625@1|root,COG0739@2|Bacteria,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
GDHHQS2_k127_5420697_5	1340493.JNIF01000003_gene3557	2.452e-20	102.0	COG3386@1|root,COG4625@1|root,COG3386@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	1.15.1.1,3.4.21.50	ko:K01337,ko:K04565,ko:K20276,ko:K21449	ko02024,ko04146,ko04213,ko05014,ko05016,ko05020,map02024,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,He_PIG,SGL
GDHHQS2_k127_5420697_4	1267535.KB906767_gene749	1.462e-65	235.0	COG1947@1|root,COG1947@2|Bacteria,3Y55D@57723|Acidobacteria,2JP3B@204432|Acidobacteriia	204432|Acidobacteriia	I	GHMP kinases C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C
GDHHQS2_k127_5420697_7	1041142.ATTP01000026_gene5081	2.729e-13	74.0	COG0671@1|root,COG0671@2|Bacteria,1R91F@1224|Proteobacteria,2U31R@28211|Alphaproteobacteria,4BCD3@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	3.1.3.2	ko:K09474	ko00740,ko01100,ko02020,map00740,map01100,map02020	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	PAP2
GDHHQS2_k127_5420697_3	1340493.JNIF01000003_gene3048	2.337e-71	259.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5437762_0	1519464.HY22_04890	8.181e-122	419.0	COG1629@1|root,COG4771@2|Bacteria,1FEFM@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS2_k127_5444012_0	234267.Acid_3066	0.0	1910.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5444012_1	1267535.KB906767_gene2982	1.395e-186	589.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
GDHHQS2_k127_5444012_4	1033730.CAHG01000008_gene3045	1.164e-25	119.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4DNCS@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
GDHHQS2_k127_5444012_2	1340493.JNIF01000004_gene528	4.332e-134	439.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,HlyD_3,PSCyt1,PSCyt2,PSD1,RNA_pol_Rpb1_5
GDHHQS2_k127_5445438_1	234267.Acid_1802	1.958e-94	313.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
GDHHQS2_k127_5445438_3	1267535.KB906767_gene2296	1.318e-56	216.0	COG4585@1|root,COG4585@2|Bacteria,3Y59R@57723|Acidobacteria	2|Bacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA_3,PAS,PAS_9,Pkinase
GDHHQS2_k127_5445438_2	234267.Acid_2426	5.159e-71	248.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
GDHHQS2_k127_5445438_0	1340493.JNIF01000003_gene1813	2.15e-155	503.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5445501_2	643473.KB235930_gene3551	3.212e-81	275.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria,1HJ3E@1161|Nostocales	1117|Cyanobacteria	S	PFAM O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
GDHHQS2_k127_5445501_6	118168.MC7420_5228	1.952e-25	117.0	COG3350@1|root,COG3350@2|Bacteria,1G6RV@1117|Cyanobacteria,1HBTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Yhs domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS2_k127_5445501_4	1267535.KB906767_gene2483	2.518e-50	188.0	COG1028@1|root,COG1028@2|Bacteria,3Y822@57723|Acidobacteria	57723|Acidobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_5445501_0	234267.Acid_4267	6.234e-166	552.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5445501_3	1123400.KB904765_gene1379	1.449e-58	222.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0438 Glycosyltransferase	VP1463	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,NAD_binding_8
GDHHQS2_k127_5445501_1	498761.HM1_1142	1.392e-89	305.0	COG0451@1|root,COG0451@2|Bacteria,1UK7W@1239|Firmicutes,25FPT@186801|Clostridia	186801|Clostridia	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
GDHHQS2_k127_5445501_7	1121035.AUCH01000018_gene2819	1.301e-05	57.0	COG0535@1|root,COG0535@2|Bacteria,1QUYT@1224|Proteobacteria,2VZN1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5445515_0	1267535.KB906767_gene4610	1.428e-190	604.0	COG1157@1|root,COG1157@2|Bacteria,3Y32E@57723|Acidobacteria,2JI3N@204432|Acidobacteriia	204432|Acidobacteriia	NU	ATP synthase alpha/beta family, nucleotide-binding domain	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS2_k127_5445515_1	234267.Acid_0341	7.972e-108	353.0	COG1536@1|root,COG1536@2|Bacteria,3Y2U7@57723|Acidobacteria	57723|Acidobacteria	N	flagellar motor switch protein FliG	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
GDHHQS2_k127_5451995_3	234267.Acid_0922	4.13e-43	159.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,3Y7VB@57723|Acidobacteria	57723|Acidobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
GDHHQS2_k127_5451995_0	234267.Acid_0921	1.924e-319	984.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5451995_5	1183438.GKIL_1494	0.0001086	45.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	mloB	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
GDHHQS2_k127_5451995_2	1173027.Mic7113_2076	6.065e-54	198.0	COG0262@1|root,COG0262@2|Bacteria,1G4ME@1117|Cyanobacteria,1HAT3@1150|Oscillatoriales	1117|Cyanobacteria	H	dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_5451995_4	1192034.CAP_7471	1.332e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
GDHHQS2_k127_5451995_1	1267535.KB906767_gene3809	4.644e-131	429.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3809|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5455817_2	234267.Acid_4585	1.015e-49	185.0	COG0518@1|root,COG0518@2|Bacteria,3Y5C2@57723|Acidobacteria	57723|Acidobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
GDHHQS2_k127_5455817_1	1340493.JNIF01000003_gene1730	6.587e-102	341.0	COG2199@1|root,COG3706@2|Bacteria,3Y7SF@57723|Acidobacteria	57723|Acidobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_5455817_0	1267535.KB906767_gene879	1.594e-150	494.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5455817_3	1469607.KK073768_gene2776	2.837e-49	190.0	COG0612@1|root,COG0612@2|Bacteria,1G303@1117|Cyanobacteria,1HJ8Q@1161|Nostocales	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5462582_2	234267.Acid_2982	2.702e-30	123.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5462582_1	1267535.KB906767_gene562	3.074e-36	147.0	COG1438@1|root,COG1438@2|Bacteria,3Y551@57723|Acidobacteria	57723|Acidobacteria	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
GDHHQS2_k127_5462582_0	234267.Acid_2504	2.154e-170	542.0	COG0165@1|root,COG0165@2|Bacteria,3Y36Y@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS2_k127_5463973_3	234267.Acid_2420	1.296e-18	87.0	COG1529@1|root,COG1529@2|Bacteria,3Y2ME@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_5463973_1	234267.Acid_2419	5.591e-83	280.0	COG2080@1|root,COG2080@2|Bacteria,3Y4DP@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2,TAT_signal
GDHHQS2_k127_5463973_0	521674.Plim_3949	1.82e-151	491.0	COG3119@1|root,COG3119@2|Bacteria,2J2HU@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5463973_2	234267.Acid_7510	4.369e-56	212.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5466289_4	864069.MicloDRAFT_00004300	9.142e-10	63.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_23,HTH_Tnp_4,rve
GDHHQS2_k127_5466289_3	485913.Krac_11000	2.608e-47	175.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5	-	-	DDE_Tnp_ISAZ013,Peripla_BP_3
GDHHQS2_k127_5466289_1	298653.Franean1_1779	4.817e-103	351.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4ERCG@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E2 component	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_5466289_2	1340493.JNIF01000004_gene488	2.683e-73	255.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
GDHHQS2_k127_5466289_0	234267.Acid_0912	4.986e-218	684.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria	57723|Acidobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_5469211_0	1121459.AQXE01000001_gene2755	2.054e-72	265.0	28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,42YXC@68525|delta/epsilon subdivisions,2WTJ0@28221|Deltaproteobacteria,2M9DF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
GDHHQS2_k127_5469211_2	1158150.KB906242_gene222	2.833e-05	54.0	2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,1SPVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage T7 capsid assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T7_Capsid
GDHHQS2_k127_5469211_1	1121459.AQXE01000001_gene2751	6.431e-07	60.0	28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,42Z7V@68525|delta/epsilon subdivisions,2WTZ3@28221|Deltaproteobacteria,2M8NA@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5470719_0	1267535.KB906767_gene1683	2.23e-173	563.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim,Prenyltrans
GDHHQS2_k127_5470719_3	1227739.Hsw_2577	2.553e-11	72.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia	976|Bacteroidetes	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_5470719_1	502025.Hoch_4014	8.321e-160	528.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria,1PEGY@1224|Proteobacteria,4345A@68525|delta/epsilon subdivisions,2X3ZH@28221|Deltaproteobacteria,2YXPP@29|Myxococcales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_5470719_2	1173026.Glo7428_3606	1.398e-33	143.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
GDHHQS2_k127_547395_1	880072.Desac_1270	4.995e-87	305.0	COG1061@1|root,COG1061@2|Bacteria,1R1EJ@1224|Proteobacteria	1224|Proteobacteria	KL	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
GDHHQS2_k127_547395_0	886293.Sinac_7090	2.125e-125	426.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5475420_1	234267.Acid_5307	1.071e-73	256.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria	57723|Acidobacteria	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,E1_dh,OxoGdeHyase_C,Transket_pyr
GDHHQS2_k127_5475420_2	1267535.KB906767_gene5101	3.258e-63	229.0	COG0565@1|root,COG0565@2|Bacteria,3Y4F6@57723|Acidobacteria,2JJ6S@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM tRNA rRNA methyltransferase, SpoU	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS2_k127_5475420_3	344747.PM8797T_13433	2.103e-35	139.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5475420_0	344747.PM8797T_00067	1.023e-134	444.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5475420_4	1340493.JNIF01000003_gene2735	4.527e-06	53.0	COG2304@1|root,COG2304@2|Bacteria,3Y8A4@57723|Acidobacteria	57723|Acidobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_5478736_0	344747.PM8797T_00644	5.148e-189	617.0	COG2010@1|root,COG2010@2|Bacteria,2IWY5@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PA14,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5478736_1	234267.Acid_3126	8.81e-15	77.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5479174_1	452637.Oter_2583	2.24e-137	440.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS2_k127_5487013_2	1192034.CAP_2547	7.138e-05	47.0	2EHQB@1|root,33BG3@2|Bacteria,1R2TB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5487013_0	234267.Acid_1308	7.254e-161	519.0	COG2308@1|root,COG2308@2|Bacteria,3Y6VU@57723|Acidobacteria	57723|Acidobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5487013_3	927677.ALVU02000005_gene485	0.0009726	42.0	COG1961@1|root,COG1961@2|Bacteria,1GARG@1117|Cyanobacteria	1117|Cyanobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Resolvase
GDHHQS2_k127_5487013_1	234267.Acid_3690	1.178e-112	388.0	COG1629@1|root,COG1629@2|Bacteria,3Y9AK@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_5496941_0	234267.Acid_1640	9.165e-300	936.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_5504861_1	1340493.JNIF01000004_gene52	7.335e-117	379.0	COG0362@1|root,COG0362@2|Bacteria,3Y990@57723|Acidobacteria	57723|Acidobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS2_k127_5504861_2	497964.CfE428DRAFT_2562	3.672e-95	322.0	COG0657@1|root,COG0657@2|Bacteria,46VFE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS2_k127_5504861_0	1267535.KB906767_gene2310	1.341e-206	653.0	COG4948@1|root,COG4948@2|Bacteria,3Y4P2@57723|Acidobacteria,2JP41@204432|Acidobacteriia	204432|Acidobacteriia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5504861_3	909663.KI867150_gene2770	1.035e-27	112.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS2_k127_5506728_8	234267.Acid_3444	3.347e-102	359.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5506728_12	1340493.JNIF01000003_gene1826	5.715e-88	314.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Phosphodiest
GDHHQS2_k127_5506728_6	234267.Acid_3693	8.515e-124	431.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_5506728_2	234267.Acid_6537	1.231e-173	562.0	COG1073@1|root,COG1073@2|Bacteria,3Y6M5@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5506728_0	414684.RC1_0547	1.241e-220	705.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GDHHQS2_k127_5506728_15	278963.ATWD01000001_gene3409	1.143e-38	148.0	COG3695@1|root,COG3695@2|Bacteria,3Y5FU@57723|Acidobacteria,2JK0H@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
GDHHQS2_k127_5506728_19	224911.27351000	8.938e-09	64.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U0ZD@28211|Alphaproteobacteria,3JY8Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.52	ko:K22213	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_2
GDHHQS2_k127_5506728_21	1469607.KK073769_gene6107	7.086e-07	58.0	COG0864@1|root,COG0864@2|Bacteria,1G9E4@1117|Cyanobacteria,1HPW8@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5506728_16	933262.AXAM01000028_gene3322	1.635e-33	133.0	COG2337@1|root,COG2337@2|Bacteria,1RIPH@1224|Proteobacteria,42UKM@68525|delta/epsilon subdivisions,2WQZB@28221|Deltaproteobacteria,2MMDH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_5506728_7	1123242.JH636435_gene1598	1.354e-109	364.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_5506728_3	234267.Acid_4125	2.757e-171	554.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5506728_5	1340493.JNIF01000003_gene4681	1.781e-150	494.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5506728_9	234267.Acid_4127	7.011e-101	338.0	COG0429@1|root,COG0429@2|Bacteria,3Y3MP@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_5506728_10	1267535.KB906767_gene1314	8.285e-96	319.0	COG3605@1|root,COG3707@1|root,COG3605@2|Bacteria,COG3707@2|Bacteria,3Y72Q@57723|Acidobacteria,2JP7X@204432|Acidobacteriia	2|Bacteria	T	GAF domain	nasR	-	4.6.1.1	ko:K01768,ko:K02584,ko:K07183,ko:K22010	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00839	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03000	-	-	-	ANTAR,GAF_2,Response_reg
GDHHQS2_k127_5506728_13	1340493.JNIF01000003_gene3797	6.844e-49	178.0	COG0745@1|root,COG0745@2|Bacteria,3Y55U@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_5506728_14	234267.Acid_5367	1.478e-43	170.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
GDHHQS2_k127_5506728_22	1121033.AUCF01000008_gene5611	0.0001724	51.0	COG0835@1|root,COG0835@2|Bacteria,1N7QA@1224|Proteobacteria,2UF8V@28211|Alphaproteobacteria,2JUIA@204441|Rhodospirillales	204441|Rhodospirillales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_5506728_1	1210884.HG799462_gene9180	7.35e-205	659.0	COG2217@1|root,COG2217@2|Bacteria,2IWRY@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
GDHHQS2_k127_5506728_18	215803.DB30_7169	3.301e-14	73.0	COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,43C27@68525|delta/epsilon subdivisions,2X7CS@28221|Deltaproteobacteria,2YZQH@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_5506728_20	1037409.BJ6T_33830	2.744e-07	60.0	2A6U5@1|root,30VND@2|Bacteria,1RANQ@1224|Proteobacteria,2U6DY@28211|Alphaproteobacteria,3JYH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5506728_17	234267.Acid_4171	8.151e-16	86.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_5506728_4	1267535.KB906767_gene248	3.452e-152	488.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_5506728_11	1144310.PMI07_005783	4.484e-95	331.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
GDHHQS2_k127_5520094_2	1297742.A176_06444	1.222e-32	140.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5520094_1	240016.ABIZ01000001_gene875	2.235e-127	421.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_5520094_0	234267.Acid_1749	1.327e-183	597.0	COG1073@1|root,COG3250@1|root,COG1073@2|Bacteria,COG3250@2|Bacteria,3Y652@57723|Acidobacteria	57723|Acidobacteria	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5520094_5	1144275.COCOR_02141	2.58e-11	72.0	COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS2_k127_5520094_4	866536.Belba_2348	7.684e-12	74.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,47RAX@768503|Cytophagia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS2_k127_5520094_3	338963.Pcar_1382	8.445e-15	81.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
GDHHQS2_k127_5520094_6	1121438.JNJA01000024_gene4027	0.0003798	44.0	COG4644@1|root,COG4644@2|Bacteria,1MUIU@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
GDHHQS2_k127_5527929_0	1340493.JNIF01000004_gene1098	8.901e-165	554.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5527929_1	1125863.JAFN01000001_gene3134	8.703e-56	214.0	COG2050@1|root,COG3303@1|root,COG2050@2|Bacteria,COG3303@2|Bacteria,1R0AE@1224|Proteobacteria,43CSS@68525|delta/epsilon subdivisions,2WU2I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
GDHHQS2_k127_5531844_2	886293.Sinac_2838	7.336e-66	229.0	COG0673@1|root,COG0673@2|Bacteria,2IY5Y@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5531844_1	313628.LNTAR_22304	1.108e-126	419.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_5531844_3	886293.Sinac_4651	1.94e-22	109.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
GDHHQS2_k127_5531844_0	234267.Acid_6431	3.258e-248	781.0	COG0155@1|root,COG0155@2|Bacteria,3Y2R8@57723|Acidobacteria	57723|Acidobacteria	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
GDHHQS2_k127_5531844_4	1267535.KB906767_gene1940	9.227e-21	93.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	VY92_08690	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
GDHHQS2_k127_5534903_0	234267.Acid_3529	3.846e-113	370.0	COG0169@1|root,COG0169@2|Bacteria,3Y2Y4@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K00014,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
GDHHQS2_k127_5534903_1	452637.Oter_3715	6.013e-51	193.0	COG3132@1|root,COG3132@2|Bacteria,46VIH@74201|Verrucomicrobia,3K85I@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
GDHHQS2_k127_5534903_2	1500301.JQMF01000012_gene5288	1.227e-35	137.0	COG0454@1|root,COG0454@2|Bacteria,1RDGT@1224|Proteobacteria,2TRF5@28211|Alphaproteobacteria,4BP39@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_553540_1	1340493.JNIF01000003_gene2974	1.701e-51	186.0	COG1253@1|root,COG1253@2|Bacteria,3Y2KE@57723|Acidobacteria	57723|Acidobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_553540_0	234267.Acid_6443	0.0	1264.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS2_k127_5536643_0	278963.ATWD01000001_gene1304	3.243e-317	999.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5537788_5	536019.Mesop_0670	1.82e-27	126.0	COG5427@1|root,COG5427@2|Bacteria,1R7G0@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
GDHHQS2_k127_5537788_4	1121957.ATVL01000014_gene1467	1.162e-47	193.0	2DXH7@1|root,3450G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5537788_3	349521.HCH_06120	2.361e-53	193.0	2DVDS@1|root,33VER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5537788_0	234267.Acid_5471	5.61e-183	603.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_5537788_1	234267.Acid_7048	7.646e-154	491.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS2_k127_5537788_2	234267.Acid_7049	3.756e-74	256.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria	57723|Acidobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5564126_1	240016.ABIZ01000001_gene5926	8.477e-67	242.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
GDHHQS2_k127_5564126_5	1267534.KB906755_gene4275	4.949e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria,2JI8K@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_5564126_2	247490.KSU1_B0364	7.976e-44	180.0	COG4191@1|root,COG4191@2|Bacteria,2J2BM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_5564126_0	234267.Acid_0743	4.344e-154	500.0	COG0304@1|root,COG0304@2|Bacteria,3Y2NT@57723|Acidobacteria	57723|Acidobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_5564126_4	1340493.JNIF01000003_gene2927	2.884e-20	92.0	COG0236@1|root,COG0236@2|Bacteria,3Y8JV@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS2_k127_5564126_3	234267.Acid_0745	2.52e-36	142.0	COG0726@1|root,COG0726@2|Bacteria,3Y4FK@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
GDHHQS2_k127_5565678_0	234267.Acid_7283	5.587e-167	532.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria	57723|Acidobacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5565678_9	765913.ThidrDRAFT_4186	8.587e-31	123.0	COG1598@1|root,COG1598@2|Bacteria,1NFAZ@1224|Proteobacteria,1SFC1@1236|Gammaproteobacteria,1WZCW@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5565678_1	1267535.KB906767_gene4273	2.926e-100	334.0	COG1028@1|root,COG1028@2|Bacteria,3Y7U3@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_5565678_6	234267.Acid_7091	3.404e-56	199.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria	57723|Acidobacteria	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS2_k127_5565678_7	1267535.KB906767_gene744	1.33e-45	169.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria	57723|Acidobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS2_k127_5565678_8	1267535.KB906767_gene745	2.422e-42	161.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS2_k127_5565678_4	234267.Acid_7094	8.942e-71	244.0	COG0193@1|root,COG0193@2|Bacteria,3Y48V@57723|Acidobacteria	57723|Acidobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS2_k127_5565678_3	1267535.KB906767_gene747	3.536e-75	261.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS2_k127_5565678_5	344747.PM8797T_02199	6.818e-65	229.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5567886_1	794903.OPIT5_17425	1.913e-14	84.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
GDHHQS2_k127_5567886_0	1396418.BATQ01000019_gene5003	1.549e-231	747.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS2_k127_556804_0	234267.Acid_5749	4.648e-108	358.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_556804_2	234267.Acid_7063	3.525e-33	129.0	COG1724@1|root,COG1724@2|Bacteria,3Y91A@57723|Acidobacteria	57723|Acidobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_556804_3	234267.Acid_7062	4.335e-28	114.0	COG1598@1|root,COG1598@2|Bacteria,3Y5Z9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_556804_1	1192034.CAP_2547	6.824e-53	196.0	2EHQB@1|root,33BG3@2|Bacteria,1R2TB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5568574_3	886293.Sinac_2442	2.209e-120	396.0	COG2010@1|root,COG2010@2|Bacteria,2IXDW@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5568574_1	1340493.JNIF01000004_gene233	3.047e-193	614.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5568574_5	644966.Tmar_0713	5.37e-05	52.0	COG1569@1|root,COG1569@2|Bacteria,1VCZ6@1239|Firmicutes,24Q32@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS2_k127_5568574_0	234267.Acid_7035	0.0	1289.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS2_k127_5568574_2	1123020.AUIE01000031_gene2763	4.033e-169	541.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,1YD63@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5568574_4	234267.Acid_2595	1.192e-24	107.0	COG1082@1|root,COG1082@2|Bacteria,3Y7BC@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5572766_3	1340493.JNIF01000003_gene4642	5.624e-09	61.0	COG1629@1|root,COG4771@2|Bacteria	1340493.JNIF01000003_gene4642|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5572766_0	234267.Acid_2974	1.404e-250	814.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5572766_1	1340493.JNIF01000003_gene3781	3.798e-95	317.0	COG0084@1|root,COG0084@2|Bacteria,3Y4DK@57723|Acidobacteria	57723|Acidobacteria	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS2_k127_5572766_4	1121930.AQXG01000007_gene531	0.0004561	52.0	COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1IXHS@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_5572766_2	118166.JH976537_gene1470	5.916e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
GDHHQS2_k127_5578036_1	1187851.A33M_4207	7.206e-13	70.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
GDHHQS2_k127_5578036_0	1187851.A33M_4208	1.37e-219	688.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
GDHHQS2_k127_5578051_0	1267535.KB906767_gene7	6.989e-237	758.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_5580167_1	234267.Acid_0229	2.437e-66	243.0	COG2890@1|root,COG2890@2|Bacteria,3Y8Q3@57723|Acidobacteria	57723|Acidobacteria	J	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5580167_0	234267.Acid_0227	3.271e-186	591.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZF@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
GDHHQS2_k127_5580167_2	1268072.PSAB_07645	9.211e-26	123.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,26VD8@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_5584206_0	234267.Acid_5749	2.679e-105	364.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5585338_0	1340493.JNIF01000003_gene3570	1.049e-130	424.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5585338_2	649638.Trad_0085	8.123e-19	89.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_5585338_1	1340493.JNIF01000004_gene597	9.479e-56	204.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5586243_4	234267.Acid_1031	8.004e-11	63.0	COG3682@1|root,COG3682@2|Bacteria,3Y8B7@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS2_k127_5586243_2	234267.Acid_1032	1.24e-100	351.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
GDHHQS2_k127_5586243_1	234267.Acid_0004	3.361e-144	473.0	COG0457@1|root,COG0457@2|Bacteria,3Y3D1@57723|Acidobacteria	57723|Acidobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5586243_0	234267.Acid_3631	5.034e-291	916.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,3Y2UC@57723|Acidobacteria	57723|Acidobacteria	V	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343,SSF
GDHHQS2_k127_5586243_3	1267535.KB906767_gene2482	1.053e-32	128.0	COG2154@1|root,COG2154@2|Bacteria,3Y8RH@57723|Acidobacteria	57723|Acidobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS2_k127_5592025_0	395493.BegalDRAFT_2517	1.956e-64	246.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
GDHHQS2_k127_5594130_4	1123242.JH636435_gene1733	1.935e-18	94.0	2C6TH@1|root,33MU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5594130_0	682795.AciX8_3718	2.611e-223	730.0	COG1629@1|root,COG3188@1|root,COG3188@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,CarbopepD_reg_2,CarboxypepD_reg,DUF11,Plug,TonB_dep_Rec
GDHHQS2_k127_5594130_3	861299.J421_5854	1.886e-30	123.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_5594130_2	1267535.KB906767_gene263	2.568e-33	130.0	COG2128@1|root,COG2128@2|Bacteria,3Y7M3@57723|Acidobacteria	57723|Acidobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_5594130_1	234267.Acid_7856	1.685e-188	598.0	COG0305@1|root,COG0305@2|Bacteria,3Y335@57723|Acidobacteria	57723|Acidobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS2_k127_5594260_0	234267.Acid_5518	2.257e-296	921.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_5594260_1	234267.Acid_5886	1.089e-146	478.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_5594260_5	234267.Acid_1209	1.498e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_5594260_3	1340493.JNIF01000003_gene4448	7.263e-80	289.0	COG5267@1|root,COG5492@1|root,COG5267@2|Bacteria,COG5492@2|Bacteria,3Y6EE@57723|Acidobacteria	57723|Acidobacteria	N	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_5594260_4	1198452.Jab_1c20410	2.786e-65	233.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VJD4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_5594260_2	1340493.JNIF01000003_gene4447	2.804e-132	433.0	COG4102@1|root,COG4102@2|Bacteria,3Y6D8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5599078_2	204669.Acid345_2716	3.934e-08	63.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5599078_1	204669.Acid345_4117	1.342e-20	99.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS2_k127_5599078_0	1267535.KB906767_gene4469	0.0	2449.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS2_k127_5600078_2	1499967.BAYZ01000013_gene6453	2.539e-09	66.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5600078_0	1395571.TMS3_0100965	2.893e-26	112.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
GDHHQS2_k127_5600078_3	555779.Dthio_PD3181	2.357e-05	53.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5603189_4	552398.HMPREF0866_03105	1.354e-07	61.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24MKW@186801|Clostridia,3WP9N@541000|Ruminococcaceae	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS2_k127_5603189_0	1267535.KB906767_gene784	2.254e-30	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5603189_1	1487953.JMKF01000095_gene5143	7.84e-19	100.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1H8W3@1150|Oscillatoriales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5606215_5	1340493.JNIF01000003_gene2671	6.323e-41	155.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria	57723|Acidobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS2_k127_5606215_0	1340493.JNIF01000003_gene1317	2.284e-179	574.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5606215_2	234267.Acid_0850	9.623e-171	545.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS2_k127_5606215_4	1267535.KB906767_gene2445	1.765e-81	282.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia	204432|Acidobacteriia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
GDHHQS2_k127_5606215_1	234267.Acid_6670	3.706e-175	556.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria	57723|Acidobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_5606215_3	234267.Acid_6671	8.053e-133	428.0	COG3872@1|root,COG3872@2|Bacteria,3Y66K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
GDHHQS2_k127_5606915_3	765952.PUV_00440	9.518e-61	222.0	COG5459@1|root,COG5459@2|Bacteria,2JG3Q@204428|Chlamydiae	204428|Chlamydiae	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
GDHHQS2_k127_5606915_6	1449976.KALB_5005	4.284e-06	53.0	COG0500@1|root,COG0500@2|Bacteria,2I450@201174|Actinobacteria,4E505@85010|Pseudonocardiales	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
GDHHQS2_k127_5606915_4	329726.AM1_2393	6.966e-19	91.0	COG0500@1|root,COG0500@2|Bacteria,1GQRZ@1117|Cyanobacteria	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TPMT
GDHHQS2_k127_5606915_2	1340493.JNIF01000004_gene1042	2.319e-112	373.0	2DUZM@1|root,33T72@2|Bacteria,3Y7AK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5606915_0	886293.Sinac_0947	2.145e-180	581.0	COG2010@1|root,COG2010@2|Bacteria,2IY86@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5606915_1	1340493.JNIF01000004_gene773	4.28e-167	537.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5606915_5	234267.Acid_5024	4.199e-10	61.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5608652_2	1340493.JNIF01000004_gene339	1.095e-61	223.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
GDHHQS2_k127_5608652_3	234267.Acid_0365	3.954e-27	119.0	2957Q@1|root,2ZSK6@2|Bacteria,3Y95H@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5608652_4	1267535.KB906767_gene4120	5.278e-11	72.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JP0E@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5608652_0	234267.Acid_7665	3.91e-99	344.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_5608652_1	234267.Acid_7666	7.962e-69	256.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5608652_6	1382359.JIAL01000001_gene1258	0.0001175	47.0	COG1487@1|root,COG1487@2|Bacteria,3Y5YU@57723|Acidobacteria,2JK5K@204432|Acidobacteriia	204432|Acidobacteriia	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_5608652_5	1267535.KB906767_gene5331	2.418e-07	56.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria,2JP26@204432|Acidobacteriia	204432|Acidobacteriia	PQ	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5620449_0	1210884.HG799464_gene10885	2.13e-188	600.0	COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes	203682|Planctomycetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_5623266_0	1340493.JNIF01000004_gene819	1.266e-206	655.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5628721_4	234267.Acid_1804	1.986e-15	78.0	COG0571@1|root,COG0571@2|Bacteria,3Y4M2@57723|Acidobacteria	57723|Acidobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS2_k127_5628721_3	1340493.JNIF01000004_gene260	4.573e-28	122.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	MA20_44825	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_5628721_5	273677.BW34_01268	3.251e-15	85.0	COG0627@1|root,COG2340@1|root,COG3250@1|root,COG3979@1|root,COG0627@2|Bacteria,COG2340@2|Bacteria,COG3250@2|Bacteria,COG3979@2|Bacteria,2I5RD@201174|Actinobacteria,4FSB1@85023|Microbacteriaceae	201174|Actinobacteria	G	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Esterase
GDHHQS2_k127_5628721_2	1267533.KB906739_gene2502	1.073e-47	189.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_5628721_6	880070.Cycma_1902	1.673e-14	81.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5628721_1	641524.ADICYQ_3837	5.839e-169	554.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5628721_0	1340493.JNIF01000003_gene2746	6.661e-269	839.0	COG5492@1|root,COG5492@2|Bacteria,3Y7DV@57723|Acidobacteria	57723|Acidobacteria	N	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_5629888_4	765914.ThisiDRAFT_1936	2.849e-66	230.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_8,RnfC_N,SLBB
GDHHQS2_k127_5629888_0	1027273.GZ77_25355	4.206e-137	444.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XH3W@135619|Oceanospirillales	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
GDHHQS2_k127_5629888_5	987059.RBXJA2T_04968	5.207e-50	186.0	COG4659@1|root,COG4659@2|Bacteria,1R6FE@1224|Proteobacteria,2VZVP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FMN_bind	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
GDHHQS2_k127_5629888_1	519989.ECTPHS_08988	8.181e-79	271.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1WW5Q@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
GDHHQS2_k127_5629888_3	1250005.PHEL85_1699	1.57e-68	246.0	COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
GDHHQS2_k127_5629888_2	382464.ABSI01000002_gene4368	1.104e-77	267.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02287,ko:K02641,ko:K15511	ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,Fer4,NAD_binding_1
GDHHQS2_k127_5631820_1	240016.ABIZ01000001_gene4025	2.108e-27	113.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS2_k127_5631820_0	1047013.AQSP01000125_gene2637	1.646e-69	259.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
GDHHQS2_k127_5631980_3	886293.Sinac_0062	4.782e-77	270.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_5631980_2	1123508.JH636448_gene7625	1.268e-88	301.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_5631980_4	1340493.JNIF01000003_gene2266	1.019e-50	182.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,HTH_18
GDHHQS2_k127_5631980_7	1125863.JAFN01000001_gene1054	1.098e-11	73.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
GDHHQS2_k127_5631980_1	1123508.JH636450_gene7211	1.852e-120	415.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
GDHHQS2_k127_5631980_0	204669.Acid345_1524	1.302e-222	718.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,3Y40G@57723|Acidobacteria,2JIXP@204432|Acidobacteriia	204432|Acidobacteriia	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
GDHHQS2_k127_5631980_5	1123242.JH636434_gene4224	2.954e-43	164.0	COG0835@1|root,COG0835@2|Bacteria,2IZN1@203682|Planctomycetes	203682|Planctomycetes	NT	CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_5631980_6	935866.JAER01000040_gene520	7.02e-41	160.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	GAF_2,HAMP,MCPsignal,PAS_3,PAS_4
GDHHQS2_k127_5640922_3	1340493.JNIF01000003_gene4065	8.317e-12	72.0	COG1426@1|root,COG1426@2|Bacteria,3Y5KP@57723|Acidobacteria	57723|Acidobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GDHHQS2_k127_5640922_0	234267.Acid_6302	8.03e-122	400.0	COG1216@1|root,COG1216@2|Bacteria,3Y5FE@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_5640922_1	234267.Acid_6301	6.863e-113	377.0	COG2227@1|root,COG2227@2|Bacteria,3Y8XU@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS2_k127_5640922_2	234267.Acid_6300	7.8e-67	239.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25,Methyltransf_31,TehB
GDHHQS2_k127_5641025_0	1267535.KB906767_gene3810	4.685e-130	433.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5641025_1	1267534.KB906757_gene845	3.075e-72	248.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
GDHHQS2_k127_5644031_0	234267.Acid_4577	1.131e-191	610.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_5644031_1	234267.Acid_3661	1.301e-06	50.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_5666049_1	234267.Acid_4321	3.447e-83	298.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_5666049_2	234267.Acid_4320	4.022e-80	277.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_5666049_3	1047013.AQSP01000125_gene2637	2.624e-41	174.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
GDHHQS2_k127_5666049_5	1267535.KB906767_gene1320	1.424e-11	68.0	COG1629@1|root,COG1629@2|Bacteria,3Y99Y@57723|Acidobacteria,2JP0X@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_5666049_4	234267.Acid_4290	1.511e-34	150.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.5.1.23	ko:K12349	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00099	R01494	RC00064,RC00328	ko00000,ko00001,ko00002,ko01000	-	-	-	Ceramidase_alk,Ceramidse_alk_C
GDHHQS2_k127_5666049_0	344747.PM8797T_23009	1.635e-190	622.0	COG2730@1|root,COG3405@1|root,COG3979@1|root,COG4305@1|root,COG2730@2|Bacteria,COG3405@2|Bacteria,COG3979@2|Bacteria,COG4305@2|Bacteria,2J4DH@203682|Planctomycetes	203682|Planctomycetes	G	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
GDHHQS2_k127_5666049_6	272844.PAB0642	1.912e-10	74.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTXF@28890|Euryarchaeota,243GB@183968|Thermococci	183968|Thermococci	T	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GDHHQS2_k127_5666049_7	1158318.ATXC01000001_gene986	1.003e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_5666130_4	931626.Awo_c15210	2.195e-14	77.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_5666130_2	1267535.KB906767_gene1147	4.539e-74	265.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_5666130_5	1177179.A11A3_15457	0.0007059	49.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
GDHHQS2_k127_5666130_0	234267.Acid_7297	1.281e-111	371.0	COG0322@1|root,COG0322@2|Bacteria,3Y3HU@57723|Acidobacteria	57723|Acidobacteria	L	excinuclease ABC activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5666130_1	234267.Acid_7296	2.897e-104	349.0	COG0667@1|root,COG0667@2|Bacteria,3Y7UC@57723|Acidobacteria	57723|Acidobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_5666130_3	1340493.JNIF01000003_gene3561	2.218e-22	107.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5670472_5	1267535.KB906767_gene1481	9.246e-15	74.0	COG1028@1|root,COG1028@2|Bacteria	1267535.KB906767_gene1481|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5670472_1	234267.Acid_5130	3.046e-68	241.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GDHHQS2_k127_5670472_3	1144275.COCOR_03626	5.427e-61	236.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
GDHHQS2_k127_5670472_0	1131269.AQVV01000048_gene2100	6.636e-113	384.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000048_gene2100|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5670472_2	1340493.JNIF01000003_gene2354	3.545e-68	241.0	COG2360@1|root,COG2360@2|Bacteria,3Y8G4@57723|Acidobacteria	57723|Acidobacteria	O	Leucyl/phenylalanyl-tRNA protein transferase	-	-	-	-	-	-	-	-	-	-	-	-	Leu_Phe_trans
GDHHQS2_k127_5670472_6	243233.MCA0338	5.963e-06	57.0	COG3291@1|root,COG3291@2|Bacteria,1R5MQ@1224|Proteobacteria,1TI1G@1236|Gammaproteobacteria,1XGA7@135618|Methylococcales	135618|Methylococcales	C	Cytochrome c5530 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5670472_4	234267.Acid_4088	7.604e-41	163.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_5673228_2	1267535.KB906767_gene2119	1.487e-62	219.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
GDHHQS2_k127_5673228_0	234267.Acid_6981	1.81e-108	359.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GDHHQS2_k127_5673228_3	46234.ANA_C13083	1.394e-45	172.0	COG4636@1|root,COG4636@2|Bacteria,1GJ1J@1117|Cyanobacteria,1HRIH@1161|Nostocales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5673228_1	1267535.KB906767_gene4977	3.988e-91	308.0	COG0648@1|root,COG0648@2|Bacteria,3Y35C@57723|Acidobacteria,2JI8X@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS2_k127_5678904_0	1340493.JNIF01000003_gene4529	2.656e-139	463.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_568654_4	941449.dsx2_1131	2.799e-18	96.0	COG2242@1|root,COG2242@2|Bacteria,1MYGE@1224|Proteobacteria,42VGU@68525|delta/epsilon subdivisions,2WS5G@28221|Deltaproteobacteria,2M91U@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_568654_0	1267535.KB906767_gene3810	2.935e-135	452.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_568654_6	1125863.JAFN01000001_gene1706	2.241e-15	90.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	NACHT,PDZ_2,TPR_16,Trypsin_2
GDHHQS2_k127_568654_1	1340493.JNIF01000003_gene3160	7.123e-57	206.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
GDHHQS2_k127_568654_7	1192034.CAP_3219	4.474e-10	73.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_568654_5	448385.sce7839	1.506e-15	88.0	COG0845@1|root,COG0845@2|Bacteria,1R8YY@1224|Proteobacteria,42RI2@68525|delta/epsilon subdivisions,2WNRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_568654_2	448385.sce4692	8.749e-49	183.0	COG1285@1|root,COG1285@2|Bacteria,1RAIG@1224|Proteobacteria,42T1T@68525|delta/epsilon subdivisions,2WPMM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
GDHHQS2_k127_568654_3	448385.sce4691	1.602e-27	122.0	COG5036@1|root,COG5036@2|Bacteria	2|Bacteria	P	cellular response to phosphate starvation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
GDHHQS2_k127_5686929_9	234267.Acid_7123	2.938e-21	94.0	COG0438@1|root,COG0438@2|Bacteria,3Y867@57723|Acidobacteria	57723|Acidobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5686929_2	234267.Acid_7122	8.926e-137	455.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_7122|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5686929_4	234267.Acid_7120	1.882e-100	336.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
GDHHQS2_k127_5686929_3	234267.Acid_7119	1.887e-111	369.0	COG1216@1|root,COG1216@2|Bacteria,3Y7YU@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5686929_6	234267.Acid_1395	5.261e-43	168.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
GDHHQS2_k127_5686929_10	1267535.KB906767_gene4298	3.689e-21	100.0	2FE1U@1|root,34620@2|Bacteria,3Y8MC@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5686929_5	240016.ABIZ01000001_gene4025	1.529e-45	168.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS2_k127_5686929_0	1123508.JH636446_gene6244	1.231e-174	562.0	COG3653@1|root,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_5686929_1	1340493.JNIF01000003_gene3981	8.006e-149	475.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
GDHHQS2_k127_5686929_11	1340493.JNIF01000004_gene155	6.659e-06	59.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,He_PIG,Laminin_G_3,NHL,SGL
GDHHQS2_k127_5691574_6	234267.Acid_7914	4.288e-54	201.0	COG0457@1|root,COG0457@2|Bacteria,3Y7TN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5691574_5	1452718.JBOY01000032_gene44	8.411e-63	229.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	yhbE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_5691574_4	344747.PM8797T_13173	2.132e-75	262.0	COG0657@1|root,COG0657@2|Bacteria,2J37Q@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS2_k127_5691574_0	234267.Acid_2982	0.0	1218.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5691574_3	1267535.KB906767_gene3845	1.072e-87	298.0	COG1090@1|root,COG1090@2|Bacteria,3Y4IA@57723|Acidobacteria,2JKY0@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS2_k127_5691574_1	1340493.JNIF01000003_gene2831	3.667e-193	613.0	COG0415@1|root,COG0415@2|Bacteria,3Y31R@57723|Acidobacteria	57723|Acidobacteria	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
GDHHQS2_k127_5691574_2	234267.Acid_5354	6.75e-110	369.0	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,3Y49J@57723|Acidobacteria	57723|Acidobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
GDHHQS2_k127_5691574_7	331869.BAL199_14207	7.049e-06	49.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,4BS1H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_35850	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5697729_1	1340493.JNIF01000003_gene4796	7.161e-44	172.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HDOD,Response_reg
GDHHQS2_k127_5697729_0	1340493.JNIF01000003_gene4575	7.879e-206	670.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5705077_7	1379270.AUXF01000003_gene3682	4.363e-33	140.0	COG4206@1|root,COG4206@2|Bacteria,1ZSN0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5705077_8	373994.Riv7116_2894	3.145e-26	113.0	COG4636@1|root,COG4636@2|Bacteria,1G13A@1117|Cyanobacteria,1HJ80@1161|Nostocales	1117|Cyanobacteria	S	COGs COG4636 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5705077_2	1121405.dsmv_0281	1.464e-121	405.0	COG0457@1|root,COG0457@2|Bacteria,1R4UV@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5705077_1	234267.Acid_6412	1.061e-159	539.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5705077_9	234267.Acid_6775	1.584e-16	89.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KD@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5705077_5	1131813.AQVT01000001_gene1900	1.54e-47	176.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2U05J@28211|Alphaproteobacteria,1JT3M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
GDHHQS2_k127_5705077_0	1340493.JNIF01000004_gene235	2.658e-183	608.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5705077_6	234267.Acid_3052	2.395e-35	145.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	tdhA	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,STN,TonB_dep_Rec
GDHHQS2_k127_5705077_3	234267.Acid_7889	9.629e-67	233.0	COG0135@1|root,COG0135@2|Bacteria,3Y50K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS2_k127_5705077_4	234267.Acid_7890	2.055e-53	191.0	COG0134@1|root,COG0134@2|Bacteria,3Y3TH@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS2_k127_5713750_0	1267535.KB906767_gene7	8.577e-168	549.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
GDHHQS2_k127_5713937_2	1521187.JPIM01000144_gene3345	1.187e-52	193.0	COG4636@1|root,COG4636@2|Bacteria,2G98P@200795|Chloroflexi,3772T@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5713937_1	251229.Chro_4274	1.078e-83	293.0	COG2133@1|root,COG2133@2|Bacteria,1G06W@1117|Cyanobacteria,3VJXP@52604|Pleurocapsales	1117|Cyanobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_5713937_0	234267.Acid_2748	4.433e-148	478.0	COG1364@1|root,COG1364@2|Bacteria,3Y2PH@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
GDHHQS2_k127_5714620_7	63737.Npun_R6547	1.39e-05	52.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria,1HMNR@1161|Nostocales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_5714620_6	234267.Acid_2675	6.897e-06	51.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS2_k127_5714620_0	234267.Acid_5749	1.538e-231	745.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5714620_2	497964.CfE428DRAFT_2702	2.315e-110	365.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS2_k127_5714620_1	278963.ATWD01000002_gene750	4.768e-153	518.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria,2JM5C@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_5714620_3	886293.Sinac_0380	2e-80	278.0	COG3391@1|root,COG3391@2|Bacteria,2IYVS@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_5714620_5	234267.Acid_4367	2.243e-11	66.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin,YafQ_toxin
GDHHQS2_k127_5714620_4	639030.JHVA01000001_gene1886	1.074e-66	237.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5716061_4	1211115.ALIQ01000032_gene1963	2.899e-28	128.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2U18Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
GDHHQS2_k127_5716061_6	234267.Acid_4077	6.133e-20	96.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_4077|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5716061_7	1340493.JNIF01000003_gene2160	0.0004295	47.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5716061_3	234267.Acid_2221	1.174e-37	148.0	COG1989@1|root,COG1989@2|Bacteria,3Y9FS@57723|Acidobacteria	57723|Acidobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
GDHHQS2_k127_5716061_1	335543.Sfum_1628	1.314e-124	412.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_5716061_0	1340493.JNIF01000003_gene1759	5.412e-182	576.0	COG0673@1|root,COG0673@2|Bacteria,3Y63X@57723|Acidobacteria	57723|Acidobacteria	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_5716061_2	1379270.AUXF01000005_gene352	8.671e-43	158.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	4CL	-	6.2.1.12	ko:K01904	ko00130,ko00360,ko00940,ko01100,ko01110,map00130,map00360,map00940,map01100,map01110	M00039,M00137,M00350	R01616,R01943,R02194,R02221,R02255,R06583	RC00004,RC00131	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_5731656_4	234267.Acid_2549	4.858e-54	193.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria	57723|Acidobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS2_k127_5731656_6	234267.Acid_7598	1.123e-32	131.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	MA20_44825	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_5731656_7	1306174.JODP01000006_gene3725	1.904e-06	61.0	2DMJ5@1|root,32RXW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15
GDHHQS2_k127_5731656_0	234267.Acid_0709	6.116e-180	572.0	COG4656@1|root,COG4656@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
GDHHQS2_k127_5731656_3	234267.Acid_0708	5.198e-78	264.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GDHHQS2_k127_5731656_5	234267.Acid_5970	1.54e-46	185.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT,PGAP1
GDHHQS2_k127_5731656_1	234267.Acid_3066	8.204e-108	372.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5731656_2	234267.Acid_3066	1.233e-93	324.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5762548_2	234267.Acid_4475	1.384e-225	722.0	COG1629@1|root,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
GDHHQS2_k127_5762548_6	504472.Slin_1069	1.145e-84	293.0	COG1312@1|root,COG1312@2|Bacteria,4NIMS@976|Bacteroidetes,47JVK@768503|Cytophagia	976|Bacteroidetes	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_5762548_0	204669.Acid345_0515	0.0	1205.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_5762548_4	471854.Dfer_2051	2.489e-124	413.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47ND1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5762548_14	204536.SULAZ_0839	1.796e-18	95.0	COG5464@1|root,COG5464@2|Bacteria,2G54G@200783|Aquificae	200783|Aquificae	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5762548_5	1380355.JNIJ01000102_gene3019	3.227e-114	377.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3K3JQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS2_k127_5762548_8	1340493.JNIF01000003_gene4598	1.001e-71	261.0	COG2271@1|root,COG2271@2|Bacteria,3Y6U9@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5762548_7	1231057.AMGD01000004_gene2899	3.238e-79	273.0	COG0363@1|root,COG0363@2|Bacteria,1TQK7@1239|Firmicutes	1239|Firmicutes	G	Psort location Cytoplasmic, score 8.87	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS2_k127_5762548_17	1449351.RISW2_00025	5.238e-07	59.0	COG5485@1|root,COG5485@2|Bacteria,1NG9D@1224|Proteobacteria,2UH77@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GDHHQS2_k127_5762548_1	1340493.JNIF01000003_gene3756	1.142e-256	809.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_5762548_3	1340493.JNIF01000003_gene3755	1.223e-213	672.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_5762548_12	234267.Acid_5940	5.108e-23	105.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5762548_10	794903.OPIT5_25030	5.03e-26	112.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
GDHHQS2_k127_5762548_15	706587.Desti_4430	1.103e-15	79.0	COG1669@1|root,COG1669@2|Bacteria,1NABR@1224|Proteobacteria,42WE0@68525|delta/epsilon subdivisions,2WRWK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS2_k127_5762548_13	234267.Acid_3325	8.225e-23	102.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5765046_1	886293.Sinac_3870	6.666e-167	537.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5765046_2	1122137.AQXF01000003_gene2094	2.316e-141	478.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,2VGDT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_5765046_5	317619.ANKN01000111_gene1542	7.001e-41	157.0	COG4636@1|root,COG4636@2|Bacteria,1G5EI@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG4636 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5765046_0	1340493.JNIF01000003_gene3515	1.632e-186	595.0	COG2939@1|root,COG2939@2|Bacteria,3Y3DM@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
GDHHQS2_k127_5765046_3	1340493.JNIF01000004_gene755	5.79e-131	427.0	COG2382@1|root,COG2382@2|Bacteria,3Y5EH@57723|Acidobacteria	57723|Acidobacteria	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_5765046_4	1267535.KB906767_gene3264	1.693e-41	161.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS2_k127_5775282_1	886293.Sinac_0682	3.265e-130	434.0	COG0627@1|root,COG0627@2|Bacteria,2J56R@203682|Planctomycetes	203682|Planctomycetes	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5775282_2	1408254.T458_19885	1.45e-77	267.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_5775282_0	246197.MXAN_2141	4.14e-146	487.0	COG2356@1|root,COG3591@1|root,COG2356@2|Bacteria,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_1,Endonuclease_NS,Exo_endo_phos,Peptidase_S46,Trypsin_2
GDHHQS2_k127_5775282_6	1340493.JNIF01000003_gene3985	5.616e-10	67.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria	57723|Acidobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
GDHHQS2_k127_5775282_4	1232410.KI421418_gene2213	2.791e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2WNWA@28221|Deltaproteobacteria,43SHN@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5775282_5	1379270.AUXF01000005_gene358	3.464e-12	70.0	COG2261@1|root,COG2261@2|Bacteria,1ZU62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_5775282_3	1123508.JH636448_gene7645	7.991e-29	118.0	COG2764@1|root,COG2764@2|Bacteria,2IZTY@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_5779722_11	1385517.N800_00445	5.272e-23	116.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1PH1W@1224|Proteobacteria,1RRYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,P_proprotein,Reprolysin_3,Reprolysin_4
GDHHQS2_k127_5779722_4	926560.KE387027_gene1021	1.743e-118	417.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5779722_10	1267535.KB906767_gene1491	5.819e-34	133.0	COG2127@1|root,COG2127@2|Bacteria,3Y85A@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
GDHHQS2_k127_5779722_1	234267.Acid_7718	1.245e-281	891.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS2_k127_5779722_6	234267.Acid_7717	1.961e-53	194.0	COG1051@1|root,COG1051@2|Bacteria,3Y5BM@57723|Acidobacteria	57723|Acidobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_5779722_3	234267.Acid_5848	1.242e-135	462.0	COG2982@1|root,COG2982@2|Bacteria,3Y3Z4@57723|Acidobacteria	57723|Acidobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
GDHHQS2_k127_5779722_8	234267.Acid_5849	4.071e-43	170.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS2_k127_5779722_2	234267.Acid_5850	1.001e-140	456.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS2_k127_5779722_9	1192034.CAP_7194	3.282e-40	166.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS2_k127_5779722_0	1254432.SCE1572_17235	0.0	1138.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS2_k127_5779722_5	234267.Acid_4998	3.29e-59	212.0	COG2017@1|root,COG2017@2|Bacteria,3Y7G9@57723|Acidobacteria	57723|Acidobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
GDHHQS2_k127_5783642_0	234267.Acid_6854	2.151e-215	710.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5783642_1	234267.Acid_2463	3.771e-95	319.0	COG2133@1|root,COG2133@2|Bacteria,3Y81J@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_5785383_1	671143.DAMO_2591	6.107e-23	109.0	2E0UX@1|root,32WC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GDHHQS2_k127_5785383_0	1125863.JAFN01000001_gene873	4.255e-119	394.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
GDHHQS2_k127_5785383_2	1267534.KB906761_gene1214	2.782e-17	83.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria,2JHUP@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_5786418_4	69395.JQLZ01000005_gene3819	9.64e-62	214.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_5786418_2	378806.STAUR_6365	5.864e-84	285.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria,438WP@68525|delta/epsilon subdivisions,2X9RW@28221|Deltaproteobacteria,2YY15@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
GDHHQS2_k127_5786418_0	661478.OP10G_0931	1.425e-213	679.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	ompA	-	-	ko:K02557,ko:K03640,ko:K12216	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.A.30.1,2.C.1.2,3.A.7.9.1	-	-	OmpA
GDHHQS2_k127_5786418_1	661478.OP10G_0930	2.194e-92	314.0	COG0600@1|root,COG0600@2|Bacteria	2|Bacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	MA20_34185	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS2_k127_5786418_3	760192.Halhy_4286	2.316e-82	293.0	COG1116@1|root,COG1116@2|Bacteria,4NNV0@976|Bacteroidetes,1IY1G@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1116 ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	3.6.3.25	ko:K02045,ko:K02049	ko00920,ko02010,map00920,map02010	M00185,M00188	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran
GDHHQS2_k127_5787330_1	570967.JMLV01000002_gene1584	1.008e-49	186.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2JRRJ@204441|Rhodospirillales	204441|Rhodospirillales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS2_k127_5787330_2	1163617.SCD_n02116	1.009e-17	87.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
GDHHQS2_k127_5787330_3	883126.HMPREF9710_05108	0.0005426	49.0	COG3134@1|root,COG3134@2|Bacteria,1N0SK@1224|Proteobacteria,2WIIM@28216|Betaproteobacteria,474FG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
GDHHQS2_k127_5787330_0	323848.Nmul_A1509	6.729e-52	194.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,373MJ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Pfam:UPF0118	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS2_k127_579306_2	234267.Acid_3977	1.176e-17	87.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_579306_4	1340493.JNIF01000004_gene564	4.849e-05	48.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_579306_3	1340493.JNIF01000004_gene564	2.738e-06	50.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_579306_1	1133849.O3I_036940	1.162e-148	478.0	COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria,4FZXS@85025|Nocardiaceae	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_579306_0	234267.Acid_7897	1.154e-205	660.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5794311_2	1267535.KB906767_gene4517	4.061e-22	97.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	gbd	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_5794311_0	1267535.KB906767_gene4516	1.957e-188	599.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
GDHHQS2_k127_5794311_1	1267535.KB906767_gene4514	2.318e-153	493.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_5798919_4	1340493.JNIF01000003_gene3819	8.867e-15	78.0	COG0267@1|root,COG0267@2|Bacteria,3Y8W0@57723|Acidobacteria	57723|Acidobacteria	J	TIGRFAM ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GDHHQS2_k127_5798919_3	1122134.KB893650_gene746	1.637e-28	115.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1XKMF@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
GDHHQS2_k127_5798919_1	234267.Acid_1244	1.656e-179	571.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_5798919_0	234267.Acid_1243	0.0	1035.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_5798919_2	1123242.JH636434_gene5302	2.205e-61	222.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5800215_0	234267.Acid_3405	5.917e-283	878.0	COG2303@1|root,COG2303@2|Bacteria,3Y6FS@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_5800215_4	1340493.JNIF01000003_gene2412	1.641e-41	159.0	COG0251@1|root,COG0251@2|Bacteria,3Y8KT@57723|Acidobacteria	57723|Acidobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_5800215_1	1340493.JNIF01000003_gene2600	1.858e-215	689.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria	57723|Acidobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
GDHHQS2_k127_5800215_2	234267.Acid_3413	4.187e-214	672.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_5800215_3	861299.J421_4344	1.294e-60	215.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
GDHHQS2_k127_5800215_6	1210884.HG799465_gene11339	1.437e-21	98.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_5800215_7	1340493.JNIF01000003_gene1861	3.81e-14	76.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
GDHHQS2_k127_5800848_4	251221.35210737	0.0004185	44.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G065@1117|Cyanobacteria	1117|Cyanobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
GDHHQS2_k127_5800848_3	509635.N824_19145	3.261e-07	59.0	COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_5800848_0	886293.Sinac_0686	4.602e-106	372.0	28JXN@1|root,2Z9N3@2|Bacteria,2IXIH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS2_k127_5800848_1	1123070.KB899268_gene2418	6.206e-86	312.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA,VCBS
GDHHQS2_k127_5800848_2	234267.Acid_0296	2.036e-76	262.0	COG1194@1|root,COG1194@2|Bacteria,3Y50Y@57723|Acidobacteria	57723|Acidobacteria	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
GDHHQS2_k127_5802540_4	682795.AciX8_4085	4.176e-18	92.0	COG0823@1|root,COG0823@2|Bacteria,3Y4FU@57723|Acidobacteria,2JJ6C@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_5802540_0	1340493.JNIF01000003_gene4471	4.927e-205	663.0	COG2304@1|root,COG2304@2|Bacteria,3Y5S3@57723|Acidobacteria	57723|Acidobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GDHHQS2_k127_5802540_1	1340493.JNIF01000003_gene3565	4.711e-203	673.0	COG1984@1|root,COG1984@2|Bacteria,3Y9AB@57723|Acidobacteria	57723|Acidobacteria	E	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5802540_6	566466.NOR53_2766	3.276e-07	63.0	COG2010@1|root,COG3420@1|root,COG2010@2|Bacteria,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,1T2I7@1236|Gammaproteobacteria,1J4SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3420 Nitrous oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
GDHHQS2_k127_5802540_5	1150864.MILUP08_44115	2.043e-08	67.0	COG5563@1|root,COG5563@2|Bacteria,2GRWY@201174|Actinobacteria,4DMB3@85008|Micromonosporales	201174|Actinobacteria	S	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5802540_2	1267535.KB906767_gene4240	2.57e-117	404.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
GDHHQS2_k127_5802540_3	1340493.JNIF01000003_gene1451	4.045e-34	143.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
GDHHQS2_k127_5802805_1	1408254.T458_12950	1.712e-08	57.0	COG1595@1|root,COG1595@2|Bacteria,1VIG7@1239|Firmicutes,4HTNK@91061|Bacilli,26U1D@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5802805_0	215803.DB30_2987	1.579e-120	409.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,42QGZ@68525|delta/epsilon subdivisions,2WKE6@28221|Deltaproteobacteria,2YYP7@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
GDHHQS2_k127_5823137_0	1082931.KKY_123	1.092e-41	162.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5824118_0	105420.BBPO01000125_gene4714	3.713e-55	209.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,2NHJ4@228398|Streptacidiphilus	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
GDHHQS2_k127_5824118_1	886293.Sinac_5031	1.048e-15	81.0	COG0526@1|root,COG3170@1|root,COG0526@2|Bacteria,COG3170@2|Bacteria,2J1AY@203682|Planctomycetes	203682|Planctomycetes	CO	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5828057_0	1267535.KB906767_gene2325	2.381e-212	668.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_5828057_3	234267.Acid_0485	9.139e-37	142.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_0485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5828057_1	1340493.JNIF01000003_gene2495	3.718e-165	529.0	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS2_k127_5828057_2	1267535.KB906767_gene3335	4.694e-39	152.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,NMT1,SBP_bac_3
GDHHQS2_k127_5831113_0	234267.Acid_5660	8.538e-140	453.0	COG0285@1|root,COG0285@2|Bacteria,3Y3ZA@57723|Acidobacteria	57723|Acidobacteria	H	Mur ligase, middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_5831113_2	1340493.JNIF01000004_gene174	3.585e-15	90.0	2DTNA@1|root,33M1Q@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
GDHHQS2_k127_5833756_4	861299.J421_5716	1.446e-11	74.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5833756_1	234267.Acid_4024	7.331e-116	393.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XC@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5833756_3	234267.Acid_4023	6.324e-35	136.0	COG1695@1|root,COG1695@2|Bacteria,3Y7SR@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_5833756_0	1183438.GKIL_3395	6.698e-147	507.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_5833756_2	234267.Acid_3878	5.274e-95	341.0	COG1045@1|root,COG1045@2|Bacteria,3Y4HF@57723|Acidobacteria	57723|Acidobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
GDHHQS2_k127_5833756_5	1410674.JNKU01000002_gene2330	2.812e-05	46.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae	91061|Bacilli	F	ComE operon protein 2	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GDHHQS2_k127_5836533_3	1238182.C882_4545	1.244e-33	134.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2TRJE@28211|Alphaproteobacteria,2JPPB@204441|Rhodospirillales	204441|Rhodospirillales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
GDHHQS2_k127_5836533_2	234267.Acid_2498	9.925e-110	369.0	COG2307@1|root,COG2307@2|Bacteria,3Y3AM@57723|Acidobacteria	57723|Acidobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
GDHHQS2_k127_5836533_0	234267.Acid_2499	3.673e-240	751.0	COG2308@1|root,COG2308@2|Bacteria,3Y2FR@57723|Acidobacteria	57723|Acidobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
GDHHQS2_k127_5836533_1	1340493.JNIF01000004_gene480	3.72e-196	621.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_5837120_3	234267.Acid_2355	1.752e-41	154.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_5837120_1	1340493.JNIF01000003_gene2816	3.711e-75	264.0	COG1561@1|root,COG1561@2|Bacteria,3Y2HQ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GDHHQS2_k127_5837120_2	1267535.KB906767_gene1436	1.217e-74	261.0	COG0194@1|root,COG0194@2|Bacteria,3Y2JW@57723|Acidobacteria,2JJ0I@204432|Acidobacteriia	204432|Acidobacteriia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS2_k127_5837120_4	1340493.JNIF01000003_gene2811	1.703e-21	98.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
GDHHQS2_k127_5837120_0	234267.Acid_2351	2.725e-153	492.0	COG0452@1|root,COG0452@2|Bacteria,3Y2QJ@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS2_k127_5840779_3	1118054.CAGW01000062_gene2301	4.996e-43	165.0	COG2124@1|root,COG2124@2|Bacteria,1TSC5@1239|Firmicutes,4HBG5@91061|Bacilli,26TAC@186822|Paenibacillaceae	91061|Bacilli	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS2_k127_5840779_2	886293.Sinac_5965	8.414e-104	354.0	COG0526@1|root,COG2010@1|root,COG0526@2|Bacteria,COG2010@2|Bacteria,2IWVQ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C
GDHHQS2_k127_5840779_0	1267535.KB906767_gene74	4.363e-162	524.0	COG1032@1|root,COG1032@2|Bacteria,3Y7DR@57723|Acidobacteria	57723|Acidobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_5840779_1	1267535.KB906767_gene75	4.675e-107	356.0	COG1181@1|root,COG1181@2|Bacteria,3Y7GI@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
GDHHQS2_k127_5849363_3	234267.Acid_1306	2.785e-100	346.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5849363_1	1267535.KB906767_gene1681	1.542e-158	512.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_5849363_2	234267.Acid_0692	3.677e-133	436.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria	57723|Acidobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_5849363_0	234267.Acid_0691	1.734e-160	512.0	COG0012@1|root,COG0012@2|Bacteria,3Y3D9@57723|Acidobacteria	57723|Acidobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS2_k127_5852372_6	1267535.KB906767_gene903	2.35e-113	376.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA2	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_5852372_10	1267535.KB906767_gene500	2.316e-27	123.0	29DWE@1|root,300UA@2|Bacteria,3Y9FG@57723|Acidobacteria,2JP7R@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
GDHHQS2_k127_5852372_1	404589.Anae109_0573	1.87e-248	785.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS2_k127_5852372_5	1340493.JNIF01000003_gene3308	3.437e-136	440.0	COG0451@1|root,COG0451@2|Bacteria,3Y5IZ@57723|Acidobacteria	57723|Acidobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_5852372_2	1340493.JNIF01000003_gene3309	1.046e-238	745.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria	57723|Acidobacteria	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GDHHQS2_k127_5852372_7	1267535.KB906767_gene3339	2.08e-112	369.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
GDHHQS2_k127_5852372_4	1267535.KB906767_gene1567	3.126e-152	490.0	COG3391@1|root,COG3391@2|Bacteria,3Y7A2@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
GDHHQS2_k127_5852372_13	234267.Acid_4404	8.07e-12	75.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GDHHQS2_k127_5852372_11	1267535.KB906767_gene2461	9.014e-27	119.0	2CB8T@1|root,349A2@2|Bacteria,3Y8JH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
GDHHQS2_k127_5852372_9	326424.FRAAL0581	7.155e-48	181.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_5852372_3	404380.Gbem_3035	1.144e-165	544.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
GDHHQS2_k127_5852372_0	314230.DSM3645_17480	0.0	1043.0	COG0542@1|root,COG0542@2|Bacteria,2IWVE@203682|Planctomycetes	203682|Planctomycetes	O	TIGRFAM type VI secretion ATPase, ClpV1 family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
GDHHQS2_k127_5852372_8	1267535.KB906767_gene2498	2.212e-48	176.0	COG3520@1|root,COG3520@2|Bacteria,3Y49W@57723|Acidobacteria,2JMM9@204432|Acidobacteriia	204432|Acidobacteriia	S	type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
GDHHQS2_k127_585909_1	1188256.BASI01000005_gene2035	3.469e-16	91.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2TR9F@28211|Alphaproteobacteria,3FE41@34008|Rhodovulum	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N
GDHHQS2_k127_586057_2	1123276.KB893251_gene3657	1.51e-123	406.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_586057_0	1297865.APJD01000003_gene6058	7.288e-182	587.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,3JVJZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_586057_1	234267.Acid_7606	1.831e-141	466.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5860936_0	1267535.KB906767_gene2278	1.602e-142	467.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_5860936_1	1267535.KB906767_gene942	7.801e-37	144.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5861173_1	1379270.AUXF01000002_gene1719	2.854e-41	163.0	COG1044@1|root,COG1044@2|Bacteria	2|Bacteria	M	lipid A biosynthetic process	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
GDHHQS2_k127_5861173_3	373994.Riv7116_5909	0.0009088	51.0	COG2230@1|root,COG4122@1|root,COG2230@2|Bacteria,COG4122@2|Bacteria,1GK4H@1117|Cyanobacteria,1HRBS@1161|Nostocales	1117|Cyanobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_5861173_0	240016.ABIZ01000001_gene2839	5.993e-67	246.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Mg_trans_NIPA
GDHHQS2_k127_5861173_2	671143.DAMO_0917	8.415e-26	109.0	COG0615@1|root,COG0615@2|Bacteria,2NRS5@2323|unclassified Bacteria	2|Bacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS2_k127_5863099_0	234267.Acid_1317	4.551e-185	591.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
GDHHQS2_k127_5865458_2	1340493.JNIF01000003_gene2874	1.272e-87	290.0	COG0407@1|root,COG0407@2|Bacteria,3Y44R@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS2_k127_5865458_1	234267.Acid_5204	7.744e-152	492.0	COG1232@1|root,COG1232@2|Bacteria,3Y2X5@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS2_k127_5865458_3	234267.Acid_4321	7.491e-09	67.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_5865458_4	1137269.AZWL01000034_gene2458	8.13e-08	59.0	COG1848@1|root,COG1848@2|Bacteria,2IPKR@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_5865458_0	234267.Acid_3444	5.792e-155	522.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5868944_1	1120950.KB892778_gene1023	1.013e-95	322.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,4DUDP@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotriesterase family	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
GDHHQS2_k127_5868944_7	429009.Adeg_0155	0.0001288	50.0	28QQ1@1|root,2ZD5J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5868944_0	309801.trd_A0425	3.041e-120	404.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
GDHHQS2_k127_5868944_5	926560.KE387023_gene2287	9.154e-12	69.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_5868944_6	234267.Acid_0310	1.156e-11	74.0	2DZHS@1|root,32VB2@2|Bacteria,3Y54X@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
GDHHQS2_k127_5868944_2	234267.Acid_0312	2.432e-79	269.0	COG1595@1|root,COG1595@2|Bacteria,3Y2V2@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5868944_3	234267.Acid_0313	1.598e-47	173.0	COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria	57723|Acidobacteria	C	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS2_k127_5876896_3	1340493.JNIF01000004_gene785	3.77e-96	322.0	COG0115@1|root,COG0115@2|Bacteria,3Y6HY@57723|Acidobacteria	57723|Acidobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_5876896_4	234267.Acid_1392	2.393e-90	312.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	3.6.3.38,3.6.3.40	ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,LysM,Wzt_C
GDHHQS2_k127_5876896_0	234267.Acid_1122	9.224e-151	485.0	COG1506@1|root,COG1506@2|Bacteria,3Y3MA@57723|Acidobacteria	57723|Acidobacteria	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS2_k127_5876896_2	234267.Acid_5230	1.283e-112	369.0	COG0489@1|root,COG0489@2|Bacteria,3Y38H@57723|Acidobacteria	57723|Acidobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS2_k127_5876896_6	543728.Vapar_0895	0.0003116	44.0	28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,2VI2S@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5887518_0	234267.Acid_6854	2.867e-159	532.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5887518_1	1267533.KB906735_gene4668	4.772e-06	53.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_589218_0	946483.Cenrod_0168	1.997e-173	552.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria,4AJXR@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10,PAS_4
GDHHQS2_k127_589218_1	234267.Acid_3583	3.091e-106	373.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_589252_7	1380391.JIAS01000005_gene2416	3.022e-10	63.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_589252_8	504472.Slin_3517	2.705e-05	49.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_589252_1	234267.Acid_0701	3.562e-91	305.0	COG1413@1|root,COG1413@2|Bacteria,3Y7N7@57723|Acidobacteria	57723|Acidobacteria	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_589252_9	1268635.Loa_01400	0.0003668	51.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria,1JC79@118969|Legionellales	118969|Legionellales	S	Haloacid dehalogenase-like hydrolase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS2_k127_589252_6	118163.Ple7327_2772	1.617e-12	70.0	COG4634@1|root,COG4634@2|Bacteria,1G79I@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GDHHQS2_k127_589252_2	234267.Acid_5681	2.137e-23	105.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GDHHQS2_k127_589252_5	1121116.KB894784_gene40	1.587e-15	78.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,2VKPT@28216|Betaproteobacteria,4ABS0@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS2_k127_589252_0	1267535.KB906767_gene942	1.062e-150	506.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5892577_0	1173023.KE650772_gene5633	1.354e-73	265.0	COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1JK0D@1189|Stigonemataceae	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_5908830_0	661478.OP10G_2561	2.463e-36	141.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
GDHHQS2_k127_5908830_1	278957.ABEA03000041_gene2041	9.738e-18	89.0	COG1848@1|root,COG1848@2|Bacteria,46XWY@74201|Verrucomicrobia,3K8HY@414999|Opitutae	414999|Opitutae	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_5908830_3	794903.OPIT5_01990	1.286e-07	56.0	COG4118@1|root,COG4118@2|Bacteria,46XWT@74201|Verrucomicrobia,3K8HF@414999|Opitutae	414999|Opitutae	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_5908830_2	1396141.BATP01000001_gene5356	4.22e-16	83.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_5910866_4	1340493.JNIF01000004_gene819	9.262e-44	162.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5910866_1	1340493.JNIF01000004_gene818	4.586e-228	713.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5910866_6	234267.Acid_7860	4.01e-09	62.0	COG1595@1|root,COG1595@2|Bacteria,3Y4FY@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_5910866_0	1340493.JNIF01000004_gene20	4.716e-237	741.0	COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_5910866_3	317936.Nos7107_1353	6.209e-59	208.0	COG2128@1|root,COG2128@2|Bacteria,1G8U8@1117|Cyanobacteria,1HN6W@1161|Nostocales	1117|Cyanobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS2_k127_5910866_5	1123279.ATUS01000003_gene506	2.751e-21	108.0	COG2234@1|root,COG2234@2|Bacteria,1R2N8@1224|Proteobacteria,1T5U9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5910866_2	1340493.JNIF01000004_gene907	4.554e-87	290.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria	57723|Acidobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS2_k127_5912132_1	1340493.JNIF01000003_gene4447	1.124e-45	174.0	COG4102@1|root,COG4102@2|Bacteria,3Y6D8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5912132_0	1340493.JNIF01000003_gene4448	3.216e-122	424.0	COG5267@1|root,COG5492@1|root,COG5267@2|Bacteria,COG5492@2|Bacteria,3Y6EE@57723|Acidobacteria	57723|Acidobacteria	N	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_5912319_7	1267535.KB906767_gene2204	1.353e-18	102.0	COG0454@1|root,COG0456@2|Bacteria,3Y5KS@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS2_k127_5912319_2	234267.Acid_2118	1.011e-156	529.0	COG0438@1|root,COG0438@2|Bacteria,3Y64B@57723|Acidobacteria	2|Bacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GDHHQS2_k127_5912319_4	234267.Acid_2117	4.168e-101	342.0	COG2271@1|root,COG2271@2|Bacteria,3Y6CQ@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS2_k127_5912319_6	344747.PM8797T_04990	7.684e-69	243.0	COG3618@1|root,COG3618@2|Bacteria,2IY4K@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_5912319_3	1123242.JH636435_gene1206	6.053e-150	481.0	COG3291@1|root,COG3291@2|Bacteria,2J3CN@203682|Planctomycetes	203682|Planctomycetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5912319_0	1340493.JNIF01000004_gene735	0.0	1259.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5912319_1	1340493.JNIF01000004_gene734	5.121e-264	817.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5912319_5	886293.Sinac_7229	9.928e-78	267.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5914924_0	234267.Acid_0830	6.758e-261	817.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_5914924_4	234267.Acid_5322	2.298e-121	399.0	COG3802@1|root,COG3802@2|Bacteria,3Y6GZ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5914924_6	1123023.JIAI01000008_gene1271	4.823e-52	201.0	COG0715@1|root,COG0715@2|Bacteria,2GNMC@201174|Actinobacteria,4E006@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_5914924_10	1173028.ANKO01000117_gene5934	2.742e-07	54.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GDHHQS2_k127_5914924_7	243230.DR_1612	4.455e-27	115.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	DUF4388,Robl_LC7
GDHHQS2_k127_5914924_11	595460.RRSWK_05890	4.662e-07	57.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5914924_3	530564.Psta_1325	8.431e-123	408.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_5914924_1	1340493.JNIF01000003_gene4121	2.496e-253	795.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5914924_2	234267.Acid_1510	4.553e-143	473.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5914924_8	234267.Acid_6154	5.625e-25	107.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_5917440_0	1347392.CCEZ01000044_gene595	6.428e-271	848.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,36EHS@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_5917440_2	383372.Rcas_4027	1.158e-44	163.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi,375U3@32061|Chloroflexia	32061|Chloroflexia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GDHHQS2_k127_5917440_1	479434.Sthe_1036	1.091e-74	256.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,27XVD@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GDHHQS2_k127_5917440_3	309801.trd_0983	6.779e-12	67.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,27XF6@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GDHHQS2_k127_5921273_0	234267.Acid_5749	1.667e-147	492.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5926505_0	1340493.JNIF01000004_gene278	2.823e-299	931.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PD40,PSCyt1,PSCyt2,PSD1,WD40
GDHHQS2_k127_5931014_1	1340493.JNIF01000004_gene597	2.125e-91	313.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5931014_0	234267.Acid_0024	7.416e-189	621.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_5931014_3	326427.Cagg_2103	3.975e-13	76.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Glycos_transf_2,HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_5931014_2	1121957.ATVL01000008_gene4538	3.335e-18	91.0	COG2067@1|root,COG2067@2|Bacteria,4NJB3@976|Bacteroidetes,47JGU@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
GDHHQS2_k127_5941893_2	1242864.D187_003284	4.141e-49	179.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_5941893_4	388467.A19Y_2309	1.063e-35	156.0	COG4249@1|root,COG4249@2|Bacteria,1G9TD@1117|Cyanobacteria	1117|Cyanobacteria	KLT	protein containing caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
GDHHQS2_k127_5941893_6	1111069.TCCBUS3UF1_1100	4.651e-08	57.0	COG1414@1|root,COG1414@2|Bacteria,1WIBR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GDHHQS2_k127_5941893_1	1037409.BJ6T_46980	7.377e-91	315.0	COG0329@1|root,COG0329@2|Bacteria,1PE99@1224|Proteobacteria,2TSAK@28211|Alphaproteobacteria,3JWWX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_5941893_7	247490.KSU1_D0502	6.353e-06	50.0	COG3415@1|root,COG3415@2|Bacteria,2J51E@203682|Planctomycetes	203682|Planctomycetes	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS2_k127_5941893_3	1267535.KB906767_gene3443	3.575e-38	151.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5941893_5	1340493.JNIF01000003_gene2575	2.289e-31	133.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_5941893_0	1267535.KB906767_gene310	2.566e-139	454.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_5944760_8	1123242.JH636434_gene3519	1.541e-68	239.0	COG1136@1|root,COG1136@2|Bacteria,2IZ2X@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
GDHHQS2_k127_5944760_0	344747.PM8797T_12748	1.7e-195	649.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2IYHP@203682|Planctomycetes	203682|Planctomycetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5944760_3	929562.Emtol_2237	2.438e-119	389.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_5944760_11	1469607.KK073768_gene4045	1.654e-24	105.0	COG3502@1|root,COG3502@2|Bacteria,1G99N@1117|Cyanobacteria,1HP7D@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF952)	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
GDHHQS2_k127_5944760_7	1122919.KB905549_gene2079	9.582e-79	273.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,26TEW@186822|Paenibacillaceae	91061|Bacilli	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS2_k127_5944760_5	448385.sce6976	2.557e-101	357.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
GDHHQS2_k127_5944760_6	234267.Acid_6156	1.252e-97	333.0	28KEJ@1|root,2ZA0T@2|Bacteria,3Y6AA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5944760_9	118161.KB235922_gene4299	1.866e-58	212.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria,3VHKB@52604|Pleurocapsales	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_5944760_1	234267.Acid_7740	3.26e-186	586.0	COG1082@1|root,COG1082@2|Bacteria,3Y2JS@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_5944760_4	234267.Acid_7742	5.389e-104	343.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
GDHHQS2_k127_5944760_2	682795.AciX8_1445	1.445e-177	569.0	COG0154@1|root,COG0154@2|Bacteria,3Y6E5@57723|Acidobacteria,2JKCM@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_5944760_12	234267.Acid_0890	5.573e-13	74.0	2C9DB@1|root,2ZU09@2|Bacteria,3Y8XC@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5944760_10	344747.PM8797T_00512	1.073e-52	192.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_5961855_0	1379698.RBG1_1C00001G1218	4.7e-94	319.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
GDHHQS2_k127_5961855_1	1267535.KB906767_gene265	4.487e-11	66.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,RNase_Zc3h12a
GDHHQS2_k127_596872_3	682795.AciX8_3444	3.002e-60	220.0	COG1409@1|root,COG1409@2|Bacteria,3Y6VA@57723|Acidobacteria,2JM69@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase	-	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
GDHHQS2_k127_596872_0	234267.Acid_0594	2.226e-159	509.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_596872_1	1123023.JIAI01000010_gene8397	4.8e-103	344.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS2_k127_596872_2	1267535.KB906767_gene2307	1.155e-85	314.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	asmA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
GDHHQS2_k127_596872_6	204669.Acid345_4155	0.0004688	46.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_596872_4	401053.AciPR4_0060	1.553e-36	149.0	COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria,2JNEB@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_5971326_1	1340493.JNIF01000004_gene818	3.991e-221	695.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5971326_0	1340493.JNIF01000004_gene819	1.294e-256	809.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5971326_2	1340493.JNIF01000003_gene3435	4.132e-61	225.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS2_k127_5971326_3	517417.Cpar_0972	3.684e-27	115.0	COG0847@1|root,COG0847@2|Bacteria,1FDW7@1090|Chlorobi	1090|Chlorobi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS2_k127_5974296_0	401053.AciPR4_1439	2.247e-152	504.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5975744_0	1537994.JQFW01000056_gene798	9.975e-110	374.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria,46CR9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_5975744_1	232721.Ajs_2262	6.437e-06	49.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VNKF@28216|Betaproteobacteria,4AATQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS2_k127_5982881_1	234267.Acid_1108	8.678e-109	381.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	2|Bacteria	I	Ankyrin repeats (many copies)	-	-	3.5.1.81	ko:K06015,ko:K06867,ko:K06886	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Prenyltrans,SQHop_cyclase_C,YkuD
GDHHQS2_k127_5982881_0	234267.Acid_0196	4.895e-212	696.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Z6@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5984422_2	1170562.Cal6303_2768	5.575e-46	175.0	COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_5984422_3	101510.RHA1_ro07227	6.779e-10	64.0	COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5984422_0	1379270.AUXF01000001_gene2132	2.957e-164	536.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_5984422_1	234267.Acid_3978	1.194e-76	282.0	COG2271@1|root,COG2271@2|Bacteria,3Y638@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5987132_4	234267.Acid_0871	2.255e-114	391.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	234267.Acid_0871|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_5987132_0	234267.Acid_2845	0.0	1969.0	COG1201@1|root,COG1201@2|Bacteria,3Y3XA@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
GDHHQS2_k127_5987132_2	1340493.JNIF01000003_gene3115	2.726e-244	760.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5987132_1	886293.Sinac_7009	0.0	1344.0	COG2010@1|root,COG2010@2|Bacteria,2IY6K@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_5987132_5	596152.DesU5LDRAFT_3431	3.899e-69	242.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,42S1Q@68525|delta/epsilon subdivisions,2WNNS@28221|Deltaproteobacteria,2MAY7@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
GDHHQS2_k127_5987132_6	1267535.KB906767_gene2483	8.459e-52	191.0	COG1028@1|root,COG1028@2|Bacteria,3Y822@57723|Acidobacteria	57723|Acidobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_5987132_7	1346791.M529_07235	6.047e-26	118.0	COG1917@1|root,COG1917@2|Bacteria,1NTJ5@1224|Proteobacteria,2UP17@28211|Alphaproteobacteria,2K9RX@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_5987132_3	234267.Acid_1761	5.194e-143	464.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria	57723|Acidobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GDHHQS2_k127_5993917_5	456442.Mboo_0096	5.524e-17	90.0	arCOG01788@1|root,arCOG01788@2157|Archaea,2XXVU@28890|Euryarchaeota,2NAW7@224756|Methanomicrobia	224756|Methanomicrobia	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
GDHHQS2_k127_5993917_1	234267.Acid_1496	7.56e-84	284.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_5993917_3	1192759.AKIB01000088_gene2323	1.104e-54	207.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
GDHHQS2_k127_5993917_0	1340493.JNIF01000003_gene1970	1.121e-98	335.0	COG0684@1|root,COG0684@2|Bacteria,3Y3TT@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS2_k127_5993917_4	234267.Acid_2690	1.568e-48	181.0	COG3391@1|root,COG3391@2|Bacteria,3Y7IA@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5997635_4	1267535.KB906767_gene690	1.071e-13	73.0	COG1028@1|root,COG1028@2|Bacteria,3Y6TA@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_5997635_2	234267.Acid_4627	7.985e-41	164.0	COG2199@1|root,COG2199@2|Bacteria,3Y6RG@57723|Acidobacteria	57723|Acidobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS2_k127_5997635_3	1267535.KB906767_gene2546	1.633e-36	142.0	2E8MJ@1|root,32S5J@2|Bacteria,3Y53W@57723|Acidobacteria,2JNZ2@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
GDHHQS2_k127_5997635_1	1267535.KB906767_gene619	1.483e-52	190.0	COG2165@1|root,COG2165@2|Bacteria,3Y4X6@57723|Acidobacteria	57723|Acidobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
GDHHQS2_k127_5997635_0	1340493.JNIF01000003_gene4493	1.187e-52	193.0	COG1360@1|root,COG1360@2|Bacteria,3Y4KZ@57723|Acidobacteria	57723|Acidobacteria	N	PFAM OmpA	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
GDHHQS2_k127_6003600_7	1267534.KB906755_gene4692	1.498e-39	153.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6003600_4	234267.Acid_4320	1.345e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_6003600_5	1047013.AQSP01000125_gene2637	2.436e-63	242.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
GDHHQS2_k127_6003600_10	234267.Acid_4367	3.749e-05	51.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin,YafQ_toxin
GDHHQS2_k127_6003600_11	234267.Acid_4366	4.901e-05	49.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS2_k127_6003600_9	40571.JOEA01000007_gene6630	1.048e-10	70.0	COG0398@1|root,COG0398@2|Bacteria,2GYCV@201174|Actinobacteria,4EAJB@85010|Pseudonocardiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_6003600_1	189753.AXAS01000036_gene7799	1.612e-168	549.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_6003600_2	1460634.JCM19037_2096	3.833e-122	405.0	COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli	91061|Bacilli	EG	COG2610 H gluconate symporter and related permeases	XK27_05475	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
GDHHQS2_k127_6003600_6	595460.RRSWK_06974	1.579e-50	199.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
GDHHQS2_k127_6003600_8	234267.Acid_0222	3.696e-13	79.0	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6010700_0	1340493.JNIF01000004_gene507	5.373e-170	553.0	COG1472@1|root,COG1472@2|Bacteria,3Y6UR@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GDHHQS2_k127_6010700_2	1340493.JNIF01000004_gene359	3.602e-127	422.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6010700_4	1210884.HG799462_gene8216	1.417e-48	195.0	COG1793@1|root,COG1793@2|Bacteria,2IYJZ@203682|Planctomycetes	203682|Planctomycetes	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_6010700_1	234267.Acid_0089	7.18e-146	483.0	COG2755@1|root,COG2755@2|Bacteria,3Y61E@57723|Acidobacteria	57723|Acidobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_6010700_3	234267.Acid_2734	1.627e-53	209.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6012844_5	1268240.ATFI01000004_gene4429	2.567e-18	87.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,2FRG0@200643|Bacteroidia,4AP5A@815|Bacteroidaceae	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_6012844_1	1340493.JNIF01000004_gene864	1.717e-143	470.0	COG1816@1|root,COG1816@2|Bacteria,3Y3TN@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS2_k127_6012844_4	530564.Psta_3954	1.909e-45	171.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
GDHHQS2_k127_6012844_2	1123242.JH636434_gene5302	1.503e-70	258.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6012844_3	1120983.KB894575_gene610	6.853e-69	243.0	COG2220@1|root,COG2220@2|Bacteria,1NNZA@1224|Proteobacteria,2U6PV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Beta-lactamase superfamily domain	-	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	LMWPc,Lactamase_B_2,Lactamase_B_3
GDHHQS2_k127_6012844_0	1267535.KB906767_gene3375	2.11e-279	873.0	COG1297@1|root,COG1297@2|Bacteria,3Y2UT@57723|Acidobacteria,2JHIU@204432|Acidobacteriia	204432|Acidobacteriia	S	Oligopeptide transporter OPT	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS2_k127_6021468_2	1340493.JNIF01000003_gene1862	1.005e-127	414.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_6021468_4	1144275.COCOR_02127	2.554e-74	282.0	COG1470@1|root,COG1470@2|Bacteria,1R2QR@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6021468_0	1340493.JNIF01000003_gene2575	0.0	1184.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6021468_3	234267.Acid_4592	2.064e-79	271.0	COG4445@1|root,COG4445@2|Bacteria,3Y8RX@57723|Acidobacteria	57723|Acidobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
GDHHQS2_k127_6021468_5	416591.Tlet_1391	1.232e-20	95.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6021468_1	1340493.JNIF01000003_gene4090	4.617e-239	774.0	COG0860@1|root,COG3227@1|root,COG0860@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783	3.4.24.28,3.5.1.28	ko:K01400,ko:K01417,ko:K01448,ko:K20274	ko01503,ko02024,map01503,map02024	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	-	-	Amidase_3,Peptidase_M36
GDHHQS2_k127_6030707_1	234267.Acid_0194	5.625e-71	252.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6030707_0	1340493.JNIF01000003_gene1961	2.938e-270	859.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
GDHHQS2_k127_6036487_0	234267.Acid_5952	8.56e-295	942.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6036487_4	765911.Thivi_4338	3.385e-20	94.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,1RPX7@1236|Gammaproteobacteria,1X0UU@135613|Chromatiales	135613|Chromatiales	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
GDHHQS2_k127_6036487_5	1125863.JAFN01000001_gene2308	9.582e-16	79.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS2_k127_6036487_2	1340493.JNIF01000003_gene3766	1.638e-72	265.0	296JB@1|root,2ZTUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6036487_3	234267.Acid_1016	7.41e-38	147.0	2DNWY@1|root,32UJU@2|Bacteria,3Y584@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
GDHHQS2_k127_6036487_1	234267.Acid_1017	8.587e-112	365.0	COG0312@1|root,COG0312@2|Bacteria,3Y39N@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS2_k127_6039931_2	1163409.UUA_08346	3.133e-57	224.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_6039931_0	344747.PM8797T_23916	5.975e-81	283.0	COG2355@1|root,COG2355@2|Bacteria,2IXYG@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_6039931_5	388467.A19Y_2459	1.278e-13	72.0	COG1598@1|root,COG1598@2|Bacteria,1G9W5@1117|Cyanobacteria,1HGUF@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6039931_4	195253.Syn6312_1482	1.237e-18	87.0	COG1724@1|root,COG1724@2|Bacteria,1GA72@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_6039931_1	1340493.JNIF01000003_gene3088	1.064e-64	236.0	COG4269@1|root,COG4269@2|Bacteria	2|Bacteria	T	membrane	yjgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF898
GDHHQS2_k127_6039931_3	330214.NIDE0306	1.72e-26	119.0	COG4783@1|root,COG4783@2|Bacteria,3J19Q@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_604064_6	1340493.JNIF01000003_gene3753	1.739e-20	102.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,Big_3_5,Glyco_hydro_25,Glyco_hydro_92,SLH,WD40,fn3
GDHHQS2_k127_604064_0	498761.HM1_1141	2.756e-140	451.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS2_k127_604064_2	498761.HM1_1151	2.164e-109	368.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_604064_3	498761.HM1_1150	1.927e-87	315.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_23
GDHHQS2_k127_604064_1	498761.HM1_1148	1.359e-136	440.0	COG0451@1|root,COG0451@2|Bacteria,1V8JZ@1239|Firmicutes,24UBU@186801|Clostridia	186801|Clostridia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_604064_4	1382303.JPOM01000001_gene1508	9.763e-44	171.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,2KG4X@204458|Caulobacterales	204458|Caulobacterales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_6,Hydrolase_like,NTP_transferase
GDHHQS2_k127_604064_5	395964.KE386496_gene2311	5.895e-24	104.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UBP8@28211|Alphaproteobacteria,3NBJ7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS2_k127_6043451_6	395961.Cyan7425_1024	1.802e-26	115.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
GDHHQS2_k127_6043451_2	357808.RoseRS_1354	3.233e-158	507.0	COG4948@1|root,COG4948@2|Bacteria,2G83T@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6043451_5	204669.Acid345_4302	1.721e-35	138.0	COG0346@1|root,COG0346@2|Bacteria,3Y8DH@57723|Acidobacteria,2JNIW@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_6043451_4	234267.Acid_7342	9.672e-55	203.0	COG2207@1|root,COG2207@2|Bacteria,3Y8UC@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
GDHHQS2_k127_6043451_7	234267.Acid_0293	4.069e-21	105.0	COG0251@1|root,COG0251@2|Bacteria,3Y810@57723|Acidobacteria	57723|Acidobacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6043451_3	234267.Acid_4780	6.656e-110	383.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS2_k127_6043451_1	234267.Acid_1822	5.852e-172	551.0	COG0531@1|root,COG0531@2|Bacteria,3Y7AX@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_6043451_8	449447.MAE_32540	6.076e-21	98.0	2F900@1|root,341BR@2|Bacteria,1GEHQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6043451_9	102125.Xen7305DRAFT_00048510	3.248e-15	81.0	2F563@1|root,33XSZ@2|Bacteria,1GDX8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6043451_0	1267535.KB906767_gene3524	7.622e-227	725.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6044190_3	1034769.KB910518_gene5131	1.291e-18	89.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,26R1A@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_6044190_0	278963.ATWD01000001_gene3283	3.507e-165	549.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6044190_1	234267.Acid_7863	9.64e-106	351.0	COG0179@1|root,COG0179@2|Bacteria,3Y30T@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GDHHQS2_k127_6044190_2	671143.DAMO_1264	1.836e-95	325.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_6044953_7	204669.Acid345_2887	3.816e-26	119.0	COG0746@1|root,COG0746@2|Bacteria,3Y5GH@57723|Acidobacteria,2JJWH@204432|Acidobacteriia	204432|Acidobacteriia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS2_k127_6044953_3	234267.Acid_4589	9.975e-120	394.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria	57723|Acidobacteria	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS2_k127_6044953_1	1267535.KB906767_gene3656	4.17e-187	619.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_6044953_2	1120949.KB903312_gene609	1.064e-173	570.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria,4DC47@85008|Micromonosporales	201174|Actinobacteria	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_6044953_0	861299.J421_5645	8.585e-250	796.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
GDHHQS2_k127_6044953_5	765420.OSCT_2507	2.034e-40	156.0	COG4636@1|root,COG4636@2|Bacteria,2G9UV@200795|Chloroflexi,37786@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6044953_6	661478.OP10G_3031	5.764e-32	130.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6044953_9	1173022.Cri9333_0929	3.02e-06	52.0	COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,1H9Q5@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6044953_8	471854.Dfer_4778	4.544e-07	55.0	COG4636@1|root,COG4636@2|Bacteria,4NQ9M@976|Bacteroidetes,47QMK@768503|Cytophagia	976|Bacteroidetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6044953_4	234267.Acid_3938	1.364e-48	194.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6047726_3	234267.Acid_5820	8.271e-101	338.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
GDHHQS2_k127_6047726_0	1340493.JNIF01000004_gene211	8.041e-225	721.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria	57723|Acidobacteria	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
GDHHQS2_k127_6047726_4	909663.KI867150_gene2770	8.727e-23	99.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS2_k127_6047726_1	1267535.KB906767_gene1540	2.09e-200	664.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6047726_2	1229172.JQFA01000002_gene3201	1.54e-190	605.0	COG0017@1|root,COG0017@2|Bacteria,1G015@1117|Cyanobacteria,1H7PZ@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_6047726_5	1403313.AXBR01000014_gene2203	3.749e-05	48.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6051934_5	1210884.HG799464_gene11097	1.307e-48	196.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
GDHHQS2_k127_6051934_1	1123242.JH636434_gene3693	1.749e-184	587.0	COG4102@1|root,COG4102@2|Bacteria,2IYN9@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6051934_0	1123242.JH636434_gene3694	1.352e-278	890.0	COG2010@1|root,COG2010@2|Bacteria,2IYF6@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6051934_4	1260251.SPISAL_05400	3.825e-52	185.0	COG1553@1|root,COG1553@2|Bacteria,1NB8E@1224|Proteobacteria,1SR7X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6051934_3	234267.Acid_6304	9.059e-71	245.0	COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_6051934_2	1267535.KB906767_gene4617	1.671e-155	501.0	COG2262@1|root,COG2262@2|Bacteria,3Y2FK@57723|Acidobacteria,2JI0F@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS2_k127_6051934_6	1267535.KB906767_gene4616	9.116e-39	147.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria	57723|Acidobacteria	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
GDHHQS2_k127_6055792_1	234267.Acid_4749	1.013e-109	359.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6055792_2	1382303.JPOM01000001_gene1755	3.292e-109	365.0	COG0863@1|root,COG0863@2|Bacteria,1PCSX@1224|Proteobacteria,2VDM9@28211|Alphaproteobacteria,2KJFE@204458|Caulobacterales	204458|Caulobacterales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GDHHQS2_k127_6055792_0	234267.Acid_7215	6.27e-219	687.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_6055792_3	1297742.A176_05966	2.396e-96	327.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,1R49D@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
GDHHQS2_k127_6055792_5	113395.AXAI01000030_gene2674	9.668e-69	244.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria,3JWU3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
GDHHQS2_k127_6055792_4	1185876.BN8_05316	3.196e-79	284.0	COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,47P83@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_6055792_6	215803.DB30_2889	7.052e-35	140.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,43A1M@68525|delta/epsilon subdivisions,2X25R@28221|Deltaproteobacteria,2YUPF@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_6071837_1	1340493.JNIF01000004_gene597	1.3e-137	464.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6071837_0	1265313.HRUBRA_01849	4.345e-193	624.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
GDHHQS2_k127_6071837_2	1499967.BAYZ01000080_gene929	8.217e-122	411.0	COG4409@1|root,COG4409@2|Bacteria,2NQRQ@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	neu	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
GDHHQS2_k127_6071837_3	1267533.KB906735_gene4449	3.629e-19	102.0	COG5492@1|root,COG5492@2|Bacteria,3Y97M@57723|Acidobacteria,2JMQ8@204432|Acidobacteriia	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,PKD,SLH,SprB
GDHHQS2_k127_6072809_1	234267.Acid_1807	2.348e-145	468.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
GDHHQS2_k127_6072809_3	1267535.KB906767_gene427	5.238e-86	289.0	2F161@1|root,33U75@2|Bacteria,3Y7M8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6072809_10	78398.KS43_02255	4.834e-06	56.0	2AIFV@1|root,318XE@2|Bacteria,1QF2N@1224|Proteobacteria,1TC4K@1236|Gammaproteobacteria,1MRI5@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6072809_0	1267533.KB906733_gene3215	3.326e-186	612.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6072809_9	344747.PM8797T_14579	3.327e-15	82.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6072809_5	1267535.KB906767_gene311	4.643e-54	193.0	COG0251@1|root,COG0251@2|Bacteria,3Y4PU@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_6072809_4	344747.PM8797T_04040	1.099e-80	289.0	COG0627@1|root,COG0627@2|Bacteria,2J2ID@203682|Planctomycetes	203682|Planctomycetes	G	Putative esterase	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase
GDHHQS2_k127_6072809_7	1403819.BATR01000191_gene6542	4.533e-30	136.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
GDHHQS2_k127_6072809_8	1210884.HG799475_gene15287	2.095e-27	129.0	COG3064@1|root,COG3064@2|Bacteria,2IWVN@203682|Planctomycetes	203682|Planctomycetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PPC
GDHHQS2_k127_6072809_2	1396141.BATP01000005_gene6037	3.995e-112	375.0	COG4102@1|root,COG4102@2|Bacteria,46TYB@74201|Verrucomicrobia,2IVHN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6072809_6	497964.CfE428DRAFT_2768	1.384e-48	183.0	COG5492@1|root,COG5492@2|Bacteria,46TTH@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_6075690_2	864051.BurJ1DRAFT_3266	9.743e-07	60.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM,fn3
GDHHQS2_k127_6075690_1	1183438.GKIL_3396	8.258e-40	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
GDHHQS2_k127_6075690_0	234267.Acid_7287	4.348e-85	286.0	COG0461@1|root,COG0461@2|Bacteria,3Y6JQ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_6078534_0	1267535.KB906767_gene3434	1.109e-268	856.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria,2JIVS@204432|Acidobacteriia	204432|Acidobacteriia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6078534_6	1267535.KB906767_gene2327	8.991e-86	287.0	COG0500@1|root,COG2226@2|Bacteria,3Y752@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6078534_3	344747.PM8797T_04565	9.889e-113	383.0	COG0673@1|root,COG0673@2|Bacteria,2IXYP@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6078534_2	1267535.KB906767_gene218	3.98e-133	438.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6078534_5	234267.Acid_2141	2.433e-109	362.0	COG0111@1|root,COG0111@2|Bacteria,3Y3VD@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
GDHHQS2_k127_6078534_9	234267.Acid_1749	1.078e-26	116.0	COG1073@1|root,COG3250@1|root,COG1073@2|Bacteria,COG3250@2|Bacteria,3Y652@57723|Acidobacteria	57723|Acidobacteria	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6078534_4	344747.PM8797T_07534	1.185e-112	371.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6078534_7	234267.Acid_0043	1.267e-47	180.0	COG2834@1|root,COG2834@2|Bacteria,3Y4XE@57723|Acidobacteria	57723|Acidobacteria	M	outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GDHHQS2_k127_6078534_8	234267.Acid_4660	5.078e-39	153.0	COG0250@1|root,COG0250@2|Bacteria,3Y83Z@57723|Acidobacteria	57723|Acidobacteria	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
GDHHQS2_k127_6078534_1	344747.PM8797T_17137	1.64e-187	599.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Sulfatase
GDHHQS2_k127_6078534_10	1121904.ARBP01000029_gene2184	8.057e-09	58.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6084589_1	682795.AciX8_0950	1.764e-47	190.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6084589_0	1328313.DS2_18318	7.157e-118	392.0	COG3119@1|root,COG3119@2|Bacteria,1RFP7@1224|Proteobacteria,1SJTS@1236|Gammaproteobacteria,469VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6086313_0	497964.CfE428DRAFT_0438	1.956e-127	424.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
GDHHQS2_k127_6086313_1	714943.Mucpa_1441	8.787e-13	74.0	COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NHHA@976|Bacteroidetes,1J194@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
GDHHQS2_k127_6097172_0	358220.C380_05915	1.423e-131	426.0	COG3391@1|root,COG3391@2|Bacteria,1MVXR@1224|Proteobacteria,2VJPF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	40-residue yvtn family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_6097172_1	192952.MM_0232	4.78e-24	117.0	COG3324@1|root,arCOG04946@2157|Archaea,2Y3YR@28890|Euryarchaeota,2NB03@224756|Methanomicrobia	224756|Methanomicrobia	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_6097172_2	1532557.JL37_02620	0.0005231	44.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJG@28216|Betaproteobacteria,3T5UZ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_6102192_2	1125863.JAFN01000001_gene562	1.834e-42	163.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS2_k127_6102192_3	234267.Acid_5653	3.992e-20	98.0	2EE9W@1|root,3384B@2|Bacteria	2|Bacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
GDHHQS2_k127_6102192_1	290397.Adeh_3087	3.894e-80	278.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
GDHHQS2_k127_6102192_0	1379698.RBG1_1C00001G0297	5.496e-133	436.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
GDHHQS2_k127_61024_4	316056.RPC_3165	1.65e-08	59.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,3JSBD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_32450	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_61024_1	204669.Acid345_4155	2.662e-60	233.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_61024_0	234267.Acid_0596	8.755e-105	352.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS2_k127_61024_2	1340493.JNIF01000003_gene3829	2.564e-39	152.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6109635_5	215803.DB30_3861	3.281e-11	69.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2YYMZ@29|Myxococcales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS2_k127_6109635_3	395961.Cyan7425_2280	7.56e-17	82.0	COG2433@1|root,COG2433@2|Bacteria,1G2BH@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS2_k127_6109635_2	324925.Ppha_2192	4.989e-22	103.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,1FEK9@1090|Chlorobi	1090|Chlorobi	T	NACHT nucleoside triphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NACHT
GDHHQS2_k127_6109635_4	247490.KSU1_B0531	6.999e-16	89.0	COG1262@1|root,COG1262@2|Bacteria,2J3GG@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_6109635_1	649831.L083_1685	2.36e-25	123.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
GDHHQS2_k127_6109635_0	1340493.JNIF01000003_gene3109	7.917e-157	503.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_6109847_0	189753.AXAS01000041_gene2534	5.737e-76	265.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
GDHHQS2_k127_6109847_1	1266909.AUAG01000035_gene1154	5.966e-30	124.0	COG1848@1|root,COG1848@2|Bacteria,1NH4K@1224|Proteobacteria,1SINK@1236|Gammaproteobacteria,1X22T@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_6112778_1	240015.ACP_2163	5.787e-88	295.0	COG2865@1|root,COG2865@2|Bacteria,3Y5XB@57723|Acidobacteria,2JNPH@204432|Acidobacteriia	204432|Acidobacteriia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_4
GDHHQS2_k127_6112778_0	1380600.AUYN01000001_gene2885	2.651e-247	792.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
GDHHQS2_k127_6112778_3	158189.SpiBuddy_0338	4.577e-05	51.0	COG1373@1|root,COG1373@2|Bacteria,2J5MK@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_6112778_2	555779.Dthio_PD2123	3.272e-09	62.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria,42R19@68525|delta/epsilon subdivisions,2WMNW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
GDHHQS2_k127_6123800_0	234267.Acid_7415	4.055e-212	683.0	COG3188@1|root,COG3188@2|Bacteria,3Y42P@57723|Acidobacteria	57723|Acidobacteria	NU	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6129664_4	1340493.JNIF01000004_gene385	4.454e-84	281.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_6129664_0	234267.Acid_5975	5.732e-300	940.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	2|Bacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	ptpA_1	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
GDHHQS2_k127_6129664_6	1144305.PMI02_01782	2.976e-50	190.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2K2S7@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_6129664_5	1357279.N018_24270	5.829e-68	238.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,1SYDI@1236|Gammaproteobacteria,1Z4QK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	iJN746.PP_0100	Pro_CA
GDHHQS2_k127_6129664_7	1191523.MROS_1578	2.44e-24	121.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GHL10
GDHHQS2_k127_6129664_1	926549.KI421517_gene1092	1.115e-252	811.0	COG3420@1|root,COG3420@2|Bacteria,4P1XP@976|Bacteroidetes,47UIA@768503|Cytophagia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6129664_2	1340493.JNIF01000004_gene1020	1.355e-167	537.0	COG2223@1|root,COG2223@2|Bacteria,3Y3PZ@57723|Acidobacteria	57723|Acidobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6129664_3	234267.Acid_6692	2.709e-95	327.0	COG4191@1|root,COG4191@2|Bacteria,3Y4SZ@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
GDHHQS2_k127_6130028_2	1340493.JNIF01000003_gene3056	1.961e-57	209.0	COG1729@1|root,COG1729@2|Bacteria,3Y3H6@57723|Acidobacteria	57723|Acidobacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
GDHHQS2_k127_6130028_1	1340493.JNIF01000003_gene3057	8.278e-111	366.0	COG4146@1|root,COG4146@2|Bacteria	2|Bacteria	S	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_6130028_3	234267.Acid_0515	2.878e-38	153.0	COG0274@1|root,COG0274@2|Bacteria,3Y2Q4@57723|Acidobacteria	2|Bacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS2_k127_6130028_0	1340493.JNIF01000003_gene4293	2.83e-124	434.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6138336_2	234267.Acid_6234	2.652e-33	139.0	COG1682@1|root,COG1682@2|Bacteria,3Y8HI@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GDHHQS2_k127_6138336_0	234267.Acid_6233	2.173e-278	872.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS2_k127_6140561_4	641524.ADICYQ_3013	9.664e-33	134.0	COG0673@1|root,COG3733@1|root,COG0673@2|Bacteria,COG3733@2|Bacteria,4NN43@976|Bacteroidetes,47UBC@768503|Cytophagia	976|Bacteroidetes	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6140561_0	1340493.JNIF01000003_gene3872	1.082e-212	670.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343,SSF
GDHHQS2_k127_6140561_1	1340493.JNIF01000003_gene3871	7.205e-189	601.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_6140561_2	234267.Acid_1276	1.455e-171	545.0	COG0343@1|root,COG0343@2|Bacteria,3Y3CP@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS2_k127_6140561_3	234267.Acid_3066	1.665e-148	490.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6144130_1	1144275.COCOR_03006	2.977e-52	202.0	COG0438@1|root,COG0438@2|Bacteria,1NKTC@1224|Proteobacteria,430RQ@68525|delta/epsilon subdivisions,2WW6Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6144130_0	290397.Adeh_2639	5.059e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42UIR@68525|delta/epsilon subdivisions,2WTWT@28221|Deltaproteobacteria,2Z2XU@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6144130_2	1499967.BAYZ01000123_gene2532	1.709e-49	186.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_614418_1	1163408.UU9_06509	1.11e-09	69.0	COG3637@1|root,COG3637@2|Bacteria,1RJ11@1224|Proteobacteria,1SXRG@1236|Gammaproteobacteria,1X6MR@135614|Xanthomonadales	135614|Xanthomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_614418_0	234267.Acid_4498	5.184e-56	202.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6145833_1	1267535.KB906767_gene836	2.588e-128	418.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria,2JM3M@204432|Acidobacteriia	204432|Acidobacteriia	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6145833_0	1267535.KB906767_gene837	1.425e-223	700.0	COG3119@1|root,COG3119@2|Bacteria,3Y683@57723|Acidobacteria,2JM4A@204432|Acidobacteriia	204432|Acidobacteriia	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6153249_7	1283299.AUKG01000002_gene4009	2.251e-05	52.0	COG5607@1|root,COG5607@2|Bacteria,2HP53@201174|Actinobacteria,4CQGX@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
GDHHQS2_k127_6153249_4	234267.Acid_5425	3.089e-59	211.0	COG0427@1|root,COG0427@2|Bacteria,3Y3BI@57723|Acidobacteria	57723|Acidobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GDHHQS2_k127_6153249_2	234267.Acid_5425	2.583e-96	320.0	COG0427@1|root,COG0427@2|Bacteria,3Y3BI@57723|Acidobacteria	57723|Acidobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GDHHQS2_k127_6153249_6	234267.Acid_1872	1.004e-26	111.0	COG1146@1|root,COG1146@2|Bacteria,3Y8V9@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS2_k127_6153249_1	234267.Acid_1871	1.633e-142	462.0	COG0674@1|root,COG0674@2|Bacteria,3Y3NB@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.7	ko:K00186	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS2_k127_6153249_0	234267.Acid_1870	6.17e-173	561.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,3Y3G3@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.7	ko:K00187	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	POR,TPP_enzyme_C
GDHHQS2_k127_6153249_3	1382306.JNIM01000001_gene3516	1.107e-89	308.0	COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_6153249_5	1267535.KB906767_gene2875	1.767e-42	166.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_6155966_7	1340493.JNIF01000003_gene4475	2.003e-42	161.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_6155966_2	402777.KB235903_gene2334	1.946e-101	349.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1H72B@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_6155966_0	234267.Acid_0353	8.027e-160	508.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_6155966_1	234267.Acid_0352	7.922e-148	474.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS2_k127_6155966_5	234267.Acid_6713	1.21e-56	201.0	COG0864@1|root,COG0864@2|Bacteria,3Y83A@57723|Acidobacteria	57723|Acidobacteria	K	NikR C terminal nickel binding domain	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
GDHHQS2_k127_6155966_3	234267.Acid_6714	7.749e-94	316.0	COG0310@1|root,COG0310@2|Bacteria,3Y8I6@57723|Acidobacteria	57723|Acidobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
GDHHQS2_k127_6155966_6	234267.Acid_6715	7.13e-46	178.0	COG0619@1|root,COG0619@2|Bacteria,3Y92N@57723|Acidobacteria	57723|Acidobacteria	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
GDHHQS2_k127_6155966_4	234267.Acid_6716	3.702e-77	264.0	COG1122@1|root,COG1122@2|Bacteria,3Y84B@57723|Acidobacteria	57723|Acidobacteria	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
GDHHQS2_k127_6164352_1	1382359.JIAL01000001_gene986	3.364e-74	260.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_6164352_0	204669.Acid345_0146	2.434e-141	461.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_6169018_3	1267535.KB906767_gene4514	7.043e-44	162.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_6169018_1	1434325.AZQN01000002_gene946	1.736e-74	269.0	COG0673@1|root,COG0673@2|Bacteria,4NHDS@976|Bacteroidetes,47K92@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6169018_0	649638.Trad_1837	4.268e-99	339.0	COG4948@1|root,COG4948@2|Bacteria,1WMNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mandelate racemase muconate lactonizing enzyme	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6169018_4	1492738.FEM21_28300	1.018e-26	128.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,1IEXU@117743|Flavobacteriia,2NYKK@237|Flavobacterium	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
GDHHQS2_k127_6169018_2	880070.Cycma_4055	1.504e-71	273.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6179622_2	234267.Acid_6548	3.059e-219	688.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6179622_5	1340493.JNIF01000003_gene3658	5.53e-31	136.0	COG1240@1|root,COG1240@2|Bacteria,3Y474@57723|Acidobacteria	57723|Acidobacteria	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_6179622_6	1340493.JNIF01000004_gene877	7.172e-28	124.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
GDHHQS2_k127_6179622_1	1340493.JNIF01000004_gene878	1.62e-220	704.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,Peptidase_C14,TPR_2,WD40
GDHHQS2_k127_6179622_3	1267533.KB906741_gene552	1.779e-98	332.0	COG0523@1|root,COG0523@2|Bacteria,3Y69S@57723|Acidobacteria	57723|Acidobacteria	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
GDHHQS2_k127_6179622_0	234267.Acid_5570	0.0	1160.0	COG4354@1|root,COG4354@2|Bacteria,3Y2ZY@57723|Acidobacteria	57723|Acidobacteria	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
GDHHQS2_k127_6180017_5	1340493.JNIF01000003_gene2146	2.926e-65	228.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_6180017_2	1340493.JNIF01000003_gene3439	1.045e-141	463.0	COG4948@1|root,COG4948@2|Bacteria,3Y403@57723|Acidobacteria	2|Bacteria	M	mandelate racemase muconate lactonizing	-	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6180017_12	682795.AciX8_1696	6.35e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,3Y58Z@57723|Acidobacteria,2JN7R@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
GDHHQS2_k127_6180017_14	1121033.AUCF01000020_gene698	5.004e-06	61.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,2JT2W@204441|Rhodospirillales	204441|Rhodospirillales	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_4,TPR_7
GDHHQS2_k127_6180017_13	1121272.KB903289_gene4096	3.279e-11	76.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4D9E2@85008|Micromonosporales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
GDHHQS2_k127_6180017_9	1267535.KB906767_gene4622	2.013e-20	95.0	COG0571@1|root,COG0571@2|Bacteria,3Y8QY@57723|Acidobacteria	57723|Acidobacteria	K	ribonuclease III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6180017_1	1267535.KB906767_gene4852	5.493e-189	601.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	alfA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
GDHHQS2_k127_6180017_6	234267.Acid_2706	5.773e-65	235.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_6180017_0	573370.DMR_38040	1.175e-207	704.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_6180017_11	234267.Acid_6577	3.799e-15	91.0	COG1470@1|root,COG3210@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,He_PIG,PATR,SLH
GDHHQS2_k127_6180017_10	595536.ADVE02000001_gene1183	7.58e-19	104.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1MU3S@1224|Proteobacteria,2U4GD@28211|Alphaproteobacteria,370TQ@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8
GDHHQS2_k127_6180017_8	234267.Acid_7268	1.443e-22	100.0	COG1254@1|root,COG1254@2|Bacteria,3Y55N@57723|Acidobacteria	57723|Acidobacteria	C	acylphosphatase activity	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS2_k127_6180017_3	234267.Acid_7098	1.973e-74	253.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GDHHQS2_k127_6180017_4	1121875.KB907547_gene3379	8.758e-69	250.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1HZVC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
GDHHQS2_k127_6199253_0	1340493.JNIF01000003_gene1814	1.026e-120	419.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6199499_1	234267.Acid_7573	7.796e-75	266.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6199499_0	234267.Acid_7108	5.359e-150	484.0	COG3867@1|root,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	3.2.1.23,3.2.1.89	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_4,DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_53,He_PIG,RicinB_lectin_2,SLH
GDHHQS2_k127_6200305_3	234267.Acid_1760	5.155e-68	234.0	COG0566@1|root,COG0566@2|Bacteria,3Y4WG@57723|Acidobacteria	57723|Acidobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
GDHHQS2_k127_6200305_0	234267.Acid_2635	1.582e-103	340.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria	2|Bacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_6200305_1	886293.Sinac_5304	3.823e-93	310.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
GDHHQS2_k127_6200305_2	1045855.DSC_03395	3.196e-71	250.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_6202536_1	1267535.KB906767_gene1521	2.403e-72	258.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_6202536_0	1340493.JNIF01000003_gene4144	7.701e-149	479.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6204090_0	1340493.JNIF01000004_gene907	8.374e-219	688.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria	57723|Acidobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS2_k127_6204424_0	234267.Acid_5073	1.227e-22	104.0	COG1918@1|root,COG1918@2|Bacteria,3Y92B@57723|Acidobacteria	57723|Acidobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
GDHHQS2_k127_6204424_2	1396418.BATQ01000049_gene436	7.497e-08	58.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6204424_1	886293.Sinac_2390	6.194e-22	97.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6204424_3	335543.Sfum_2156	5.857e-07	58.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,42U6J@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	PFAM sulfatase	-	-	3.1.6.1,3.1.6.6	ko:K01130,ko:K01133	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Choline_sulf_C,DUF4976,HemolysinCabind,Sulfatase
GDHHQS2_k127_6211_4	1340493.JNIF01000004_gene404	5.8e-51	182.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_6211_3	1340493.JNIF01000004_gene401	1.531e-96	323.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_6211_6	446462.Amir_1749	3.354e-12	78.0	2EE91@1|root,3383F@2|Bacteria,2IAWN@201174|Actinobacteria,4EA0R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6211_5	118161.KB235922_gene2633	1.231e-36	143.0	COG0232@1|root,COG0232@2|Bacteria,1G32E@1117|Cyanobacteria,3VIG3@52604|Pleurocapsales	1117|Cyanobacteria	F	TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	iJN678.dgt	HD,HD_assoc
GDHHQS2_k127_6211_1	234267.Acid_5749	3.51e-167	556.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6211_2	399739.Pmen_3228	6.913e-135	445.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1YDPH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_6211_0	414684.RC1_0547	8.468e-227	722.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GDHHQS2_k127_6212920_2	344747.PM8797T_05840	4.264e-39	149.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_6212920_0	1340493.JNIF01000004_gene838	1.852e-64	228.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS2_k127_6212920_1	234267.Acid_6265	3.058e-56	211.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6221739_4	234267.Acid_7201	8.063e-151	488.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_6221739_1	1340493.JNIF01000004_gene871	2.987e-194	614.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_6221739_6	1340493.JNIF01000003_gene4413	4.034e-137	442.0	COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria	57723|Acidobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
GDHHQS2_k127_6221739_7	234267.Acid_0895	8.977e-133	435.0	COG1332@1|root,COG1332@2|Bacteria,3Y71E@57723|Acidobacteria	57723|Acidobacteria	L	RAMP superfamily	-	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
GDHHQS2_k127_6221739_9	1340493.JNIF01000003_gene4415	1.416e-88	304.0	COG1567@1|root,COG1567@2|Bacteria	2|Bacteria	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
GDHHQS2_k127_6221739_8	1267535.KB906767_gene2608	1.557e-130	421.0	COG1337@1|root,COG1337@2|Bacteria,3Y6QK@57723|Acidobacteria	57723|Acidobacteria	L	RAMP superfamily	-	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
GDHHQS2_k127_6221739_11	1267535.KB906767_gene2609	1.007e-66	230.0	COG1421@1|root,COG1421@2|Bacteria,3Y7KM@57723|Acidobacteria	57723|Acidobacteria	L	Pfam:DUF310	-	-	-	-	-	-	-	-	-	-	-	-	Csm2_III-A
GDHHQS2_k127_6221739_3	234267.Acid_0891	6.327e-155	507.0	COG1353@1|root,COG1353@2|Bacteria,3Y6EG@57723|Acidobacteria	57723|Acidobacteria	S	crispr-associated protein	-	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	-
GDHHQS2_k127_6221739_10	1267533.KB906733_gene3471	3.219e-78	278.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
GDHHQS2_k127_6221739_0	401053.AciPR4_1439	2.441e-212	697.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6221739_5	1123508.JH636440_gene2840	3.825e-140	460.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6221739_2	1267535.KB906767_gene2200	4.814e-194	612.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_6228177_1	314230.DSM3645_14945	2.484e-56	204.0	COG0673@1|root,COG0673@2|Bacteria,2IXUF@203682|Planctomycetes	2|Bacteria	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6228177_0	234267.Acid_1317	6.088e-122	402.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
GDHHQS2_k127_6235485_1	234267.Acid_5979	1.326e-77	266.0	COG2366@1|root,COG2366@2|Bacteria,3Y2PX@57723|Acidobacteria	2|Bacteria	S	PFAM peptidase S45 penicillin amidase	penA	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_6235485_0	497964.CfE428DRAFT_5247	5.395e-223	725.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_6235485_2	1267535.KB906767_gene2784	3.019e-68	238.0	COG3387@1|root,COG3387@2|Bacteria,3Y3QW@57723|Acidobacteria,2JIEZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF5127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127
GDHHQS2_k127_6241661_4	926569.ANT_29930	5.841e-74	252.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
GDHHQS2_k127_6241661_3	234267.Acid_2127	6.178e-86	317.0	COG4447@1|root,COG4447@2|Bacteria,3Y2XZ@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6241661_1	1340493.JNIF01000004_gene375	2.694e-114	404.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
GDHHQS2_k127_6241661_2	639030.JHVA01000001_gene2540	1.666e-91	314.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_6241661_0	886293.Sinac_7090	8.86e-149	501.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6241661_5	671143.DAMO_1180	4.126e-17	96.0	COG3177@1|root,COG3177@2|Bacteria,2NREB@2323|unclassified Bacteria	2|Bacteria	S	Filamentation induced by cAMP protein fic	fic	-	-	-	-	-	-	-	-	-	-	-	Fic
GDHHQS2_k127_6242759_1	234267.Acid_7026	5.822e-47	176.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6242759_0	234267.Acid_0593	5.082e-124	407.0	28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS2_k127_6242759_2	1123073.KB899245_gene23	1.864e-44	185.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_6247235_4	234267.Acid_6303	8.932e-08	59.0	COG1426@1|root,COG1426@2|Bacteria,3Y5KP@57723|Acidobacteria	57723|Acidobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GDHHQS2_k127_6247235_2	395963.Bind_0647	6.426e-38	156.0	COG2059@1|root,COG2059@2|Bacteria,1RCDP@1224|Proteobacteria,2U6CH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS2_k127_6247235_3	595536.ADVE02000001_gene2973	4.938e-26	115.0	COG2059@1|root,COG2059@2|Bacteria,1RGZC@1224|Proteobacteria,2UBKX@28211|Alphaproteobacteria,36ZY4@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS2_k127_6247235_0	234267.Acid_4046	8.354e-87	298.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_4046|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6247235_1	234267.Acid_1717	4.279e-85	289.0	COG0688@1|root,COG0688@2|Bacteria,3Y4AZ@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS2_k127_6248915_3	1117379.BABA_23690	1.013e-44	178.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,1ZB2I@1386|Bacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6248915_0	1267535.KB906767_gene1746	8.943e-274	862.0	COG0072@1|root,COG0072@2|Bacteria,3Y353@57723|Acidobacteria,2JIM2@204432|Acidobacteriia	204432|Acidobacteriia	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB
GDHHQS2_k127_6248915_1	1267535.KB906767_gene1733	1.014e-165	526.0	COG0016@1|root,COG0016@2|Bacteria,3Y3NJ@57723|Acidobacteria,2JIN8@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS2_k127_6248915_2	234267.Acid_2837	2.112e-89	308.0	COG0823@1|root,COG0823@2|Bacteria,3Y89F@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40
GDHHQS2_k127_6248915_5	240016.ABIZ01000001_gene5926	1.28e-06	54.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
GDHHQS2_k127_6248915_4	595460.RRSWK_04276	6.247e-07	53.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
GDHHQS2_k127_6249663_7	1144275.COCOR_04737	8.636e-11	72.0	COG2374@1|root,COG2374@2|Bacteria,1QTNH@1224|Proteobacteria,43809@68525|delta/epsilon subdivisions,2X3AA@28221|Deltaproteobacteria,2YV3X@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6249663_4	595460.RRSWK_07140	2.303e-112	376.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_6249663_1	497964.CfE428DRAFT_3913	5.884e-161	519.0	COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6249663_0	926550.CLDAP_02700	1.447e-292	915.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS2_k127_6249663_6	234267.Acid_7334	1.711e-84	290.0	COG1816@1|root,COG1816@2|Bacteria,3Y2R0@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS2_k127_6249663_3	497964.CfE428DRAFT_4235	6.314e-113	373.0	COG0673@1|root,COG0673@2|Bacteria,46UK6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6259219_1	1198114.AciX9_0376	5.538e-106	353.0	COG4591@1|root,COG4591@2|Bacteria,3Y3DS@57723|Acidobacteria,2JHS5@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6259219_3	1340493.JNIF01000003_gene4384	1.084e-82	282.0	COG1136@1|root,COG1136@2|Bacteria,3Y2QD@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6259219_4	234267.Acid_0316	1.335e-68	239.0	COG2094@1|root,COG2094@2|Bacteria,3Y5DM@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS2_k127_6259219_5	1007103.AFHW01000029_gene1633	7.046e-56	210.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,26T7K@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
GDHHQS2_k127_6259219_0	1267535.KB906767_gene4267	1.041e-115	375.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria,2JP4G@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_6259219_2	234267.Acid_2165	3.252e-99	334.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3Y6RV@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_6274526_0	344747.PM8797T_21598	6.782e-165	532.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_6274526_1	1122603.ATVI01000008_gene2258	5.233e-82	284.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria,1X3ZS@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
GDHHQS2_k127_6274526_2	1333998.M2A_1430	7.051e-42	164.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,4BQ7A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS2_k127_6281166_4	1550073.JROH01000003_gene2419	2.085e-51	190.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
GDHHQS2_k127_6281166_2	1550073.JROH01000003_gene2422	9.729e-74	260.0	COG0030@1|root,COG0030@2|Bacteria,1R1XJ@1224|Proteobacteria,2TZ6Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_6281166_0	1550073.JROH01000003_gene2421	4.246e-143	462.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,2U3JJ@28211|Alphaproteobacteria,2K6N2@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6281166_1	1550073.JROH01000003_gene2420	1.145e-94	335.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,2TUG6@28211|Alphaproteobacteria,2K1Z7@204457|Sphingomonadales	204457|Sphingomonadales	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6281166_3	522306.CAP2UW1_0955	7.24e-63	224.0	COG2242@1|root,COG2242@2|Bacteria,1RI7P@1224|Proteobacteria,2VU2N@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_6282758_6	234267.Acid_5899	4.853e-50	207.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS2_k127_6282758_1	234267.Acid_3524	4.745e-217	680.0	COG4948@1|root,COG4948@2|Bacteria,3Y403@57723|Acidobacteria	57723|Acidobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6282758_3	1340493.JNIF01000003_gene4705	2.769e-88	297.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
GDHHQS2_k127_6282758_4	234267.Acid_4237	1.765e-81	282.0	COG2386@1|root,COG2386@2|Bacteria,3Y3G1@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c-type biogenesis protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS2_k127_6282758_2	234267.Acid_4236	1.087e-92	316.0	COG1131@1|root,COG1131@2|Bacteria,3Y4M9@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS2_k127_6282758_5	234267.Acid_4235	2.764e-76	269.0	28K54@1|root,2Z9TW@2|Bacteria,3Y3Z7@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6282758_8	1267535.KB906767_gene3998	1.06e-38	155.0	2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6282758_10	1267535.KB906767_gene3999	4.554e-14	78.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
GDHHQS2_k127_6282758_0	234267.Acid_4232	7.528e-311	964.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS2_k127_6282758_7	234267.Acid_4231	2.716e-47	172.0	COG2332@1|root,COG2332@2|Bacteria,3Y57C@57723|Acidobacteria	57723|Acidobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GDHHQS2_k127_6283193_2	357808.RoseRS_2240	1.632e-31	132.0	COG1249@1|root,COG1249@2|Bacteria,2G7VE@200795|Chloroflexi	200795|Chloroflexi	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_6283193_1	1123242.JH636434_gene3975	3.136e-82	288.0	28KEJ@1|root,2ZA0T@2|Bacteria,2IZ9S@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6283193_0	234267.Acid_2721	6.237e-118	401.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_6283193_4	1330700.JQNC01000003_gene1553	2.561e-05	56.0	COG1082@1|root,COG1082@2|Bacteria,1WI0M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6289190_4	395019.Bmul_0910	2.845e-09	59.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS2_k127_6289190_1	234267.Acid_7435	2.857e-206	648.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GDHHQS2_k127_6289190_2	234267.Acid_7436	2.26e-137	449.0	COG2227@1|root,COG3206@1|root,COG2227@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K03561,ko:K07011,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.A.30.2.1,4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_6289190_0	234267.Acid_7437	6.348e-297	930.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,3Y79C@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GDHHQS2_k127_6289190_3	234267.Acid_4090	2.347e-50	184.0	COG1187@1|root,COG1187@2|Bacteria,3Y6Y9@57723|Acidobacteria	57723|Acidobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_6291852_2	1267535.KB906767_gene5220	5.875e-21	96.0	2C5RF@1|root,33T7W@2|Bacteria,3Y6IQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6291852_0	1340493.JNIF01000004_gene1022	7.276e-115	385.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6291852_1	234267.Acid_1209	1.256e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_6294606_2	143224.JQMD01000002_gene3609	7.109e-111	370.0	COG3119@1|root,COG3386@1|root,COG3119@2|Bacteria,COG3386@2|Bacteria,4NETT@976|Bacteroidetes,1HX4V@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	SGL,Sulfatase
GDHHQS2_k127_6294606_0	1267535.KB906767_gene3313	6.12e-175	561.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
GDHHQS2_k127_6294606_1	1267535.KB906767_gene3313	9.725e-114	375.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
GDHHQS2_k127_6295337_2	1185876.BN8_01972	1.761e-101	343.0	COG4948@1|root,COG4948@2|Bacteria,4NGZF@976|Bacteroidetes,47NF7@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6295337_4	1123020.AUIE01000001_gene2462	2.827e-76	267.0	COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S13Q@1236|Gammaproteobacteria,1YCZ2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_6295337_0	234267.Acid_4577	1.512e-165	540.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_6295337_5	1267535.KB906767_gene1286	7.101e-36	145.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_6295337_6	682795.AciX8_3700	2.129e-28	119.0	COG0662@1|root,COG0662@2|Bacteria,3Y8MJ@57723|Acidobacteria	57723|Acidobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6295337_1	596152.DesU5LDRAFT_3543	2.586e-109	362.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2WJH4@28221|Deltaproteobacteria,2M8II@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_6295337_3	1340493.JNIF01000003_gene1328	5.721e-88	296.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GDHHQS2_k127_629654_12	1123075.AUDP01000001_gene2335	5.283e-15	81.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3WGSP@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS2_k127_629654_9	234267.Acid_5186	5.416e-34	141.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria	2|Bacteria	S	PFAM ABC transporter	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran
GDHHQS2_k127_629654_6	234267.Acid_3830	4.495e-103	343.0	COG0395@1|root,COG0395@2|Bacteria,3Y7HR@57723|Acidobacteria	57723|Acidobacteria	G	Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
GDHHQS2_k127_629654_1	867845.KI911784_gene3137	1.38e-135	439.0	COG0330@1|root,COG0330@2|Bacteria,2GAMW@200795|Chloroflexi,3772P@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_629654_2	234267.Acid_7078	1.91e-123	402.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_629654_5	234267.Acid_2377	3.255e-116	380.0	COG0388@1|root,COG0388@2|Bacteria,3Y7FJ@57723|Acidobacteria	57723|Acidobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_629654_7	234267.Acid_3344	7.567e-95	319.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS2_k127_629654_0	1297569.MESS2_770013	5.818e-163	531.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_629654_4	1123367.C666_02100	2.947e-116	389.0	COG1234@1|root,COG2333@1|root,COG1234@2|Bacteria,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2W4KD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	tRNA 3'-trailer cleavage	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_629654_8	234267.Acid_5692	5.688e-80	276.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
GDHHQS2_k127_629654_3	1499967.BAYZ01000089_gene5014	4.209e-122	404.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GDHHQS2_k127_629654_11	1305735.JAFT01000005_gene1346	1.181e-20	97.0	COG5340@1|root,COG5340@2|Bacteria,1R80Q@1224|Proteobacteria,2U4TW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	AbiEi antitoxin C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
GDHHQS2_k127_629654_10	478741.JAFS01000001_gene1461	7.499e-28	118.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
GDHHQS2_k127_6303583_3	1353537.TP2_16275	5.596e-11	66.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,1QYHB@1224|Proteobacteria,2TXR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IK	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE,Hydrolase_4,Trans_reg_C
GDHHQS2_k127_6303583_1	1244869.H261_13179	4.988e-45	180.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria,2JZ9I@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS2_k127_6303583_0	319003.Bra1253DRAFT_07121	2.066e-67	246.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1QXEH@1224|Proteobacteria,2TX96@28211|Alphaproteobacteria,3K6W1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,FHA,Guanylate_cyc
GDHHQS2_k127_6303583_2	243231.GSU1113	4.872e-37	143.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
GDHHQS2_k127_6307367_0	886293.Sinac_7090	5.725e-122	408.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6307367_1	234267.Acid_1337	8.383e-84	285.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
GDHHQS2_k127_6307367_2	1121904.ARBP01000001_gene5553	4.769e-55	207.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
GDHHQS2_k127_6307367_3	1331060.RLDS_03315	3.222e-41	156.0	2DGG3@1|root,32U75@2|Bacteria,1RJCY@1224|Proteobacteria,2UAFV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6307460_11	926566.Terro_1186	1.55e-61	227.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Z9@57723|Acidobacteria,2JKTJ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6307460_9	1122917.KB899660_gene1601	7.512e-65	252.0	COG2273@1|root,COG2931@1|root,COG3507@1|root,COG2273@2|Bacteria,COG2931@2|Bacteria,COG3507@2|Bacteria,1TQA7@1239|Firmicutes,4HU59@91061|Bacilli,26T4N@186822|Paenibacillaceae	91061|Bacilli	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9
GDHHQS2_k127_6307460_12	926566.Terro_3180	1.891e-42	180.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pectinesterase
GDHHQS2_k127_6307460_7	264198.Reut_B3663	2.7e-92	309.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2VP8F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_6307460_2	344747.PM8797T_18876	2.82e-136	447.0	COG3119@1|root,COG3119@2|Bacteria,2J2DZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_6307460_5	234267.Acid_2255	2.047e-109	365.0	COG3618@1|root,COG3618@2|Bacteria,3Y4FF@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_6307460_8	1124780.ANNU01000071_gene1021	1.028e-84	297.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_6307460_3	204669.Acid345_3430	8.824e-135	437.0	COG0673@1|root,COG0673@2|Bacteria,3Y3FR@57723|Acidobacteria,2JKWF@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6307460_10	1267533.KB906739_gene2502	1.305e-63	241.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_6307460_13	1183438.GKIL_2277	6.011e-26	115.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
GDHHQS2_k127_6307460_4	518766.Rmar_0017	3.799e-131	434.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes	976|Bacteroidetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GDHHQS2_k127_6307460_6	518766.Rmar_0018	4.218e-108	355.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_6307460_1	880070.Cycma_1913	2.2e-151	491.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia	976|Bacteroidetes	P	Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6307460_0	1267535.KB906767_gene4405	1.104e-245	780.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6316393_0	1123508.JH636439_gene1117	1.099e-68	243.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_6316393_2	1267535.KB906767_gene1023	8.16e-22	102.0	COG4636@1|root,COG4636@2|Bacteria,3Y7WQ@57723|Acidobacteria,2JN0R@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6316393_1	1396141.BATP01000045_gene1809	1.9e-41	166.0	2DVY4@1|root,33XNN@2|Bacteria,46VB3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6316882_1	1244869.H261_06606	1.908e-117	388.0	COG1352@1|root,COG2201@1|root,COG2433@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2433@2|Bacteria,1NQTI@1224|Proteobacteria,2TRH8@28211|Alphaproteobacteria,2JQ72@204441|Rhodospirillales	204441|Rhodospirillales	NT	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
GDHHQS2_k127_6316882_0	614083.AWQR01000028_gene3128	1.294e-166	551.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VMCI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_8,PAS_9
GDHHQS2_k127_6319107_0	1267535.KB906767_gene2199	1.915e-86	295.0	COG2259@1|root,COG2259@2|Bacteria,3Y7PU@57723|Acidobacteria	57723|Acidobacteria	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6319107_1	1123023.JIAI01000008_gene1271	9.85e-84	290.0	COG0715@1|root,COG0715@2|Bacteria,2GNMC@201174|Actinobacteria,4E006@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_6329028_2	1197130.BAFM01000020_gene2797	4.754e-53	196.0	COG1028@1|root,arCOG01259@2157|Archaea,2XUXR@28890|Euryarchaeota,23TZM@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_6329028_3	864702.OsccyDRAFT_2446	6.317e-09	64.0	COG0457@1|root,COG2520@1|root,COG0457@2|Bacteria,COG2520@2|Bacteria,1G193@1117|Cyanobacteria,1HE9A@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_6329028_1	756067.MicvaDRAFT_4379	3.745e-62	231.0	COG1408@1|root,COG1408@2|Bacteria,1GQUH@1117|Cyanobacteria,1HAMV@1150|Oscillatoriales	1117|Cyanobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6329028_0	756067.MicvaDRAFT_4379	2.596e-64	236.0	COG1408@1|root,COG1408@2|Bacteria,1GQUH@1117|Cyanobacteria,1HAMV@1150|Oscillatoriales	1117|Cyanobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6330171_5	1340493.JNIF01000004_gene88	3.708e-31	125.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6330171_0	1267535.KB906767_gene448	7.485e-279	865.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria,2JI53@204432|Acidobacteriia	204432|Acidobacteriia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GDHHQS2_k127_6330171_8	278963.ATWD01000001_gene2890	0.0001291	46.0	COG3169@1|root,COG3169@2|Bacteria,3Y8QV@57723|Acidobacteria	57723|Acidobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	-	-	-	-	-	-	-	-	-	DMT_6
GDHHQS2_k127_6330171_9	1123253.AUBD01000014_gene870	0.0007031	47.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1X6P3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
GDHHQS2_k127_6330171_2	1340493.JNIF01000004_gene1048	2.339e-247	769.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6330171_1	1340493.JNIF01000004_gene1047	1.343e-251	792.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6330171_3	1340493.JNIF01000004_gene1066	2.932e-246	770.0	COG1473@1|root,COG1473@2|Bacteria	2|Bacteria	S	N-acetyldiaminopimelate deacetylase activity	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_6330171_4	1288963.ADIS_3630	6.4e-36	152.0	COG0584@1|root,COG0584@2|Bacteria,4NMIW@976|Bacteroidetes	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
GDHHQS2_k127_6330171_6	1340493.JNIF01000003_gene1452	5.629e-21	100.0	COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria	57723|Acidobacteria	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
GDHHQS2_k127_6330171_7	402881.Plav_1537	3.413e-12	70.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,2UIAY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GDHHQS2_k127_6336502_4	1151122.AQYD01000007_gene638	2.494e-34	145.0	COG3170@1|root,COG3170@2|Bacteria,2IANU@201174|Actinobacteria	201174|Actinobacteria	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
GDHHQS2_k127_6336502_5	1298880.AUEV01000015_gene169	7.568e-16	88.0	COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_6336502_2	981369.JQMJ01000004_gene4889	1.988e-45	177.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,2NH27@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_6336502_1	497964.CfE428DRAFT_4864	5.643e-60	215.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6336502_3	675812.VHA_001365	2.368e-39	165.0	COG1555@1|root,COG1555@2|Bacteria,1QWR7@1224|Proteobacteria	1224|Proteobacteria	L	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
GDHHQS2_k127_6336502_0	234267.Acid_2975	7.766e-268	857.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6338382_3	1100720.ALKN01000040_gene2252	4.701e-13	70.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria,4AD6W@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_6338382_2	926550.CLDAP_36900	8.37e-27	114.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi	200795|Chloroflexi	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS2_k127_6338382_0	1276756.AUEX01000001_gene1151	4.21e-80	278.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS2_k127_6338382_1	1122918.KB907249_gene3885	1.809e-44	176.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,4HE6D@91061|Bacilli,26RGF@186822|Paenibacillaceae	91061|Bacilli	M	enzyme of poly-gamma-glutamate biosynthesis (Capsule formation)	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS2_k127_6343625_0	926569.ANT_27490	1.261e-109	377.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,Response_reg
GDHHQS2_k127_6343625_1	234267.Acid_4321	5.933e-20	103.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_6346963_3	1340493.JNIF01000004_gene740	1.83e-77	260.0	COG0059@1|root,COG0059@2|Bacteria,3Y34M@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
GDHHQS2_k127_6346963_0	234267.Acid_0177	1.247e-283	884.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS2_k127_6346963_2	313628.LNTAR_09801	4.008e-108	366.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.12	ko:K01135,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_6346963_1	1123242.JH636435_gene1778	2.084e-170	549.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_6352672_3	234267.Acid_7665	3.334e-92	326.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_6352672_5	1340493.JNIF01000003_gene1755	1.205e-58	221.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6352672_6	330214.NIDE3451	9.328e-50	188.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_6352672_1	1267535.KB906767_gene3449	1.714e-148	481.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
GDHHQS2_k127_6352672_0	234267.Acid_7160	1.898e-188	599.0	COG0154@1|root,COG0154@2|Bacteria,3Y6WA@57723|Acidobacteria	57723|Acidobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GDHHQS2_k127_6352672_4	234267.Acid_1939	1.541e-89	313.0	COG0457@1|root,COG3303@1|root,COG0457@2|Bacteria,COG3303@2|Bacteria,3Y6HC@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16
GDHHQS2_k127_6352672_2	1267535.KB906767_gene3768	3.209e-96	337.0	COG1629@1|root,COG1629@2|Bacteria,3Y2K8@57723|Acidobacteria,2JKEC@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6355379_1	234267.Acid_1559	5.432e-207	649.0	COG0498@1|root,COG0498@2|Bacteria,3Y3G4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_6355379_0	639030.JHVA01000001_gene3707	1.599e-248	807.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6355379_3	1267535.KB906767_gene3186	2.508e-16	82.0	COG1401@1|root,COG1401@2|Bacteria	2|Bacteria	V	restriction endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF3578,DUF3883
GDHHQS2_k127_6355379_2	742726.HMPREF9448_02737	8.015e-122	408.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,2FNB7@200643|Bacteroidia,22X71@171551|Porphyromonadaceae	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS2_k127_6355379_4	278963.ATWD01000001_gene3023	5.415e-10	72.0	COG1741@1|root,COG1741@2|Bacteria,3Y4MS@57723|Acidobacteria,2JKK8@204432|Acidobacteriia	204432|Acidobacteriia	S	Pirin C-terminal cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
GDHHQS2_k127_6358106_0	234267.Acid_5783	2.176e-244	762.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_6358106_1	671143.DAMO_1527	2.589e-98	331.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GDHHQS2_k127_6358106_2	682795.AciX8_1556	2.058e-39	156.0	COG2318@1|root,COG2318@2|Bacteria,3Y4U3@57723|Acidobacteria,2JJEH@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_6360199_2	512565.AMIS_27400	4.301e-12	80.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
GDHHQS2_k127_6360199_5	103733.JNYO01000008_gene5417	2.484e-09	71.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2HEQP@201174|Actinobacteria,4DYQU@85010|Pseudonocardiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_6360199_1	234267.Acid_0721	5.144e-14	86.0	COG2373@1|root,COG2755@1|root,COG2931@1|root,COG3391@1|root,COG2373@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	psrP1	GO:0000272,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0017144,GO:0042737,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0045491,GO:0045493,GO:0046555,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884	-	ko:K12548,ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,DUF11,Lipase_GDSL_2
GDHHQS2_k127_6360199_0	1267533.KB906737_gene1923	3.072e-30	125.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
GDHHQS2_k127_6360199_3	345219.Bcoa_0910	8.855e-10	67.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,1ZB1J@1386|Bacillus	91061|Bacilli	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
GDHHQS2_k127_6365535_2	1502850.FG91_00516	4.1e-49	190.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6365535_0	1385935.N836_13420	1.101e-63	240.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1H8UK@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_6365535_4	585531.HMPREF0063_12587	4.448e-24	113.0	COG1493@1|root,COG1493@2|Bacteria,2I704@201174|Actinobacteria,4DT1I@85009|Propionibacteriales	201174|Actinobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6365535_5	797114.C475_01297	6.227e-08	64.0	arCOG03838@1|root,arCOG03838@2157|Archaea,2Y1S5@28890|Euryarchaeota,23YNA@183963|Halobacteria	183963|Halobacteria	H	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS2_k127_6365535_1	1125863.JAFN01000001_gene303	3.028e-53	214.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding
GDHHQS2_k127_6365535_3	1340493.JNIF01000003_gene4090	9.651e-41	158.0	COG0860@1|root,COG3227@1|root,COG0860@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783	3.4.24.28,3.5.1.28	ko:K01400,ko:K01417,ko:K01448,ko:K20274	ko01503,ko02024,map01503,map02024	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	-	-	Amidase_3,Peptidase_M36
GDHHQS2_k127_6376577_1	1267535.KB906767_gene2350	2.017e-24	102.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_6376577_0	1267535.KB906767_gene4615	2.304e-84	289.0	COG0053@1|root,COG0053@2|Bacteria,3Y6ZG@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_6376577_2	1144319.PMI16_03688	2.638e-08	60.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VRNF@28216|Betaproteobacteria,478SK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_6383508_2	156889.Mmc1_1108	1.341e-13	76.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria	1224|Proteobacteria	N	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_6383508_0	1340493.JNIF01000003_gene3439	2.998e-205	655.0	COG4948@1|root,COG4948@2|Bacteria,3Y403@57723|Acidobacteria	2|Bacteria	M	mandelate racemase muconate lactonizing	-	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6383508_1	1340493.JNIF01000003_gene2321	6.356e-115	389.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6385914_1	886293.Sinac_6931	1.823e-203	645.0	COG4102@1|root,COG4102@2|Bacteria,2IXNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6385914_0	682795.AciX8_2919	5.198e-261	826.0	COG1643@1|root,COG1643@2|Bacteria,3Y38N@57723|Acidobacteria,2JHKA@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
GDHHQS2_k127_6385914_2	1267535.KB906767_gene221	4.364e-122	406.0	COG1082@1|root,COG1082@2|Bacteria,3Y65C@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6385914_3	1267535.KB906767_gene219	3.278e-68	242.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_6394507_0	32057.KB217483_gene9237	9.097e-138	451.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	ychM	-	-	-	-	-	-	-	-	-	-	-	STAS_2,Sulfate_transp
GDHHQS2_k127_6394507_2	234267.Acid_6462	7.561e-67	244.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4
GDHHQS2_k127_6394507_1	1340493.JNIF01000004_gene438	2.105e-79	270.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_6394507_3	1382359.JIAL01000001_gene2561	3.032e-25	113.0	2AC2T@1|root,311KW@2|Bacteria,3Y4QM@57723|Acidobacteria,2JMHZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6400535_4	316057.RPD_0713	2.229e-28	114.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,3JRAJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS2_k127_6400535_3	78398.KS43_00025	3.339e-40	157.0	arCOG06916@1|root,30456@2|Bacteria,1R83C@1224|Proteobacteria,1RQ5P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
GDHHQS2_k127_6400535_2	1121889.AUDM01000018_gene1247	8.14e-109	362.0	COG4637@1|root,COG4637@2|Bacteria,4NFTD@976|Bacteroidetes,1HY8M@117743|Flavobacteriia,2NWA4@237|Flavobacterium	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
GDHHQS2_k127_6400535_0	1340493.JNIF01000003_gene1874	1.056e-244	763.0	COG0137@1|root,COG0137@2|Bacteria,3Y4Y9@57723|Acidobacteria	57723|Acidobacteria	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS2_k127_6400535_1	929703.KE386491_gene1630	1.464e-127	426.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_640067_5	1340493.JNIF01000004_gene934	1.035e-75	262.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	axeA	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,SASA
GDHHQS2_k127_640067_6	234267.Acid_7472	7.384e-49	177.0	COG1917@1|root,COG1917@2|Bacteria,3Y596@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_640067_2	234267.Acid_0997	1.182e-207	657.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD36	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K12429,ko:K18660,ko:K18661,ko:K18662	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_640067_3	886293.Sinac_0388	4.968e-92	317.0	COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_640067_0	234267.Acid_4034	4.095e-278	896.0	COG1629@1|root,COG5266@1|root,COG4771@2|Bacteria,COG5266@2|Bacteria,3Y42A@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_640067_1	234267.Acid_4033	2.226e-224	736.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_640067_4	234267.Acid_2556	6.229e-92	306.0	COG2252@1|root,COG2252@2|Bacteria,3Y2I3@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
GDHHQS2_k127_6401228_2	1303518.CCALI_02909	3.025e-39	154.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
GDHHQS2_k127_6401228_0	1267535.KB906767_gene5238	1.605e-49	185.0	2DZX2@1|root,32VM6@2|Bacteria,3Y88Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6401228_1	1267535.KB906767_gene5240	4.496e-44	163.0	COG3379@1|root,COG3379@2|Bacteria,3Y7CR@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_6401349_1	1267535.KB906767_gene2230	8.468e-136	458.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6401349_5	1382359.JIAL01000001_gene3034	1.442e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,3Y6T5@57723|Acidobacteria,2JMN9@204432|Acidobacteriia	204432|Acidobacteriia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_6401349_6	316056.RPC_3289	1.641e-07	56.0	28QM9@1|root,2ZD31@2|Bacteria,1NUK0@1224|Proteobacteria,2URK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
GDHHQS2_k127_6401349_2	1187851.A33M_1310	1.309e-40	155.0	28QM9@1|root,2ZD31@2|Bacteria,1NUK0@1224|Proteobacteria,2URK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
GDHHQS2_k127_6401349_3	1267535.KB906767_gene1296	2.19e-33	143.0	COG2264@1|root,COG2264@2|Bacteria,3Y5SG@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS2_k127_6401349_0	234267.Acid_1107	2.317e-216	687.0	COG0591@1|root,COG0591@2|Bacteria,3Y6FC@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS2_k127_6401349_4	234267.Acid_2315	6.336e-19	86.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_6401570_0	234267.Acid_4491	2.75e-226	706.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_6412425_0	1340493.JNIF01000004_gene649	8.44e-90	306.0	COG3266@1|root,COG3266@2|Bacteria,3Y4N4@57723|Acidobacteria	57723|Acidobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS2_k127_6412425_1	1267533.KB906742_gene676	9.243e-16	79.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria,2JM2J@204432|Acidobacteriia	204432|Acidobacteriia	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
GDHHQS2_k127_6414700_3	756272.Plabr_0480	1.485e-136	440.0	COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_6414700_2	314230.DSM3645_09722	1.382e-163	528.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6414700_1	1340493.JNIF01000003_gene4639	2.398e-249	780.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,FAD_oxidored,Fer4,NAD_binding_8,Pyr_redox_2
GDHHQS2_k127_6414700_5	234267.Acid_3780	2.442e-55	200.0	COG1496@1|root,COG1496@2|Bacteria,3Y3J1@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS2_k127_6414700_0	234267.Acid_4298	1.226e-260	814.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,3Y3DA@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_6414700_6	234267.Acid_4299	2.362e-43	162.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria	57723|Acidobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS2_k127_6414700_4	234267.Acid_4300	6.301e-63	222.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
GDHHQS2_k127_6414700_7	309799.DICTH_0560	5.708e-19	96.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_6414700_9	644107.SL1157_0664	2.995e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,4N9XG@97050|Ruegeria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	MA20_42300	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS2_k127_6414700_8	1144305.PMI02_00918	1.139e-06	57.0	COG2519@1|root,COG2519@2|Bacteria,1REXK@1224|Proteobacteria,2U905@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_6416284_2	234267.Acid_2205	3.061e-82	282.0	COG0274@1|root,COG0274@2|Bacteria,3Y2Q4@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS2_k127_6416284_3	234267.Acid_2204	1.001e-68	241.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
GDHHQS2_k127_6416284_1	234267.Acid_2371	1.951e-117	398.0	COG2215@1|root,COG2215@2|Bacteria,3Y73Y@57723|Acidobacteria	2|Bacteria	P	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	DsbD_2,NicO
GDHHQS2_k127_6416284_0	344747.PM8797T_09494	1.822e-197	634.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_09690	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6425800_6	234267.Acid_6287	0.0003164	47.0	COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF11,DUF1349,Peptidase_S8,fn3
GDHHQS2_k127_6425800_3	1210884.HG799464_gene10790	6.896e-125	412.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS2_k127_6425800_2	497964.CfE428DRAFT_4945	9.602e-127	426.0	COG1541@1|root,COG1541@2|Bacteria,46SVW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
GDHHQS2_k127_6425800_1	497964.CfE428DRAFT_5041	1.102e-162	524.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
GDHHQS2_k127_6425800_0	240016.ABIZ01000001_gene3202	1.287e-164	528.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_6425800_4	1128421.JAGA01000001_gene2345	5.716e-27	128.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3
GDHHQS2_k127_6425800_5	1177179.A11A3_06061	3.925e-12	80.0	COG3386@1|root,COG3386@2|Bacteria,1R8NE@1224|Proteobacteria,1S1N9@1236|Gammaproteobacteria,1XNUM@135619|Oceanospirillales	135619|Oceanospirillales	G	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	ASH
GDHHQS2_k127_6426043_0	1267535.KB906767_gene265	4.109e-169	543.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,RNase_Zc3h12a
GDHHQS2_k127_6426043_1	234267.Acid_4937	2.278e-144	467.0	COG0387@1|root,COG0387@2|Bacteria,3Y66M@57723|Acidobacteria	57723|Acidobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GDHHQS2_k127_6426043_4	655815.ZPR_1397	7.641e-22	102.0	COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1I28C@117743|Flavobacteriia	976|Bacteroidetes	J	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_6426043_3	234267.Acid_7896	3.799e-105	348.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS2_k127_6426043_2	234267.Acid_7895	3.575e-120	411.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6426738_2	1380390.JIAT01000014_gene6288	9.436e-10	72.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
GDHHQS2_k127_6426738_0	1340493.JNIF01000003_gene2896	8.548e-166	529.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6426738_1	204669.Acid345_2365	7.848e-93	315.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS2_k127_6427394_0	1340493.JNIF01000004_gene88	2.979e-230	748.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6442069_1	234267.Acid_1306	1.883e-85	306.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6442069_0	1267535.KB906767_gene425	0.0	1279.0	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS2_k127_6443627_0	251221.35213536	2.5e-102	372.0	COG0443@1|root,COG0443@2|Bacteria,1G1EM@1117|Cyanobacteria	1117|Cyanobacteria	O	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6443627_1	251221.35213535	2.201e-41	168.0	COG0206@1|root,COG0206@2|Bacteria,1G357@1117|Cyanobacteria	1117|Cyanobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
GDHHQS2_k127_6450972_0	596153.Alide_1658	9.568e-40	151.0	COG1672@1|root,COG1672@2|Bacteria,1MWQD@1224|Proteobacteria,2VK8E@28216|Betaproteobacteria,4ADU1@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
GDHHQS2_k127_6450972_1	1297863.APJF01000007_gene2673	1.567e-39	160.0	2EH3D@1|root,33AVD@2|Bacteria,1QR7N@1224|Proteobacteria,2TUZ2@28211|Alphaproteobacteria,3JXFI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GDHHQS2_k127_6462239_8	1340493.JNIF01000003_gene2091	3.49e-43	162.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_6462239_4	1089550.ATTH01000001_gene1968	4.746e-75	266.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1FJUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_6462239_7	1121430.JMLG01000022_gene2433	2.563e-45	181.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,261XD@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
GDHHQS2_k127_6462239_0	690850.Desaf_3621	6.132e-304	963.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_6462239_6	234267.Acid_7898	3.086e-47	175.0	COG5483@1|root,COG5483@2|Bacteria,3Y4X5@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS2_k127_6462239_3	326427.Cagg_0270	1.763e-78	274.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS2_k127_6462239_5	240016.ABIZ01000001_gene5281	6.677e-50	183.0	COG3871@1|root,COG3871@2|Bacteria,46VIW@74201|Verrucomicrobia,2IVPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
GDHHQS2_k127_6462239_1	234267.Acid_3088	2.95e-107	357.0	COG3291@1|root,COG3291@2|Bacteria,3Y76G@57723|Acidobacteria	2|Bacteria	S	Domain of Unknown Function (DUF1080)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	DUF1080,LRR_5,PKD
GDHHQS2_k127_6462239_2	1340493.JNIF01000004_gene175	7.466e-85	282.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH
GDHHQS2_k127_64629_2	1157634.KB912984_gene294	0.0002093	49.0	COG2755@1|root,COG3209@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PT-HINT,RHS_repeat
GDHHQS2_k127_64629_0	1123508.JH636440_gene2214	1.215e-81	284.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_64629_1	595460.RRSWK_00595	4.844e-67	235.0	COG1454@1|root,COG1454@2|Bacteria,2IXD7@203682|Planctomycetes	203682|Planctomycetes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_6477508_1	1340493.JNIF01000003_gene3066	5.464e-177	566.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS2_k127_6477508_2	234267.Acid_7937	2.424e-119	405.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6477508_3	1340493.JNIF01000003_gene2563	1.451e-115	376.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_6477508_4	1128421.JAGA01000003_gene2869	9.941e-88	294.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrome_C7,GSu_C4xC__C2xCH,UVR
GDHHQS2_k127_6477508_0	234267.Acid_0490	0.0	1039.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
GDHHQS2_k127_6477508_6	204669.Acid345_3002	3.504e-08	59.0	COG5557@1|root,COG5557@2|Bacteria,3Y3NS@57723|Acidobacteria,2JHIK@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS2_k127_6488086_1	680198.SCAB_18701	0.0006981	51.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Muraidase,PG_binding_1
GDHHQS2_k127_6488086_0	234267.Acid_7267	9.284e-80	285.0	COG4485@1|root,COG4485@2|Bacteria,3Y74P@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS2_k127_6489087_7	234267.Acid_5870	7.006e-28	115.0	COG1082@1|root,COG1082@2|Bacteria,3Y7AM@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6489087_0	234267.Acid_2834	2.815e-190	605.0	COG1236@1|root,COG1236@2|Bacteria,3Y6U0@57723|Acidobacteria	57723|Acidobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GDHHQS2_k127_6489087_8	35754.JNYJ01000021_gene532	2.986e-20	95.0	28XA8@1|root,2ZJ8A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6489087_4	1395587.P364_0119645	8.996e-88	299.0	COG4188@1|root,COG4188@2|Bacteria,1TREG@1239|Firmicutes,4HECF@91061|Bacilli,26WIB@186822|Paenibacillaceae	91061|Bacilli	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
GDHHQS2_k127_6489087_3	1267535.KB906767_gene5504	1.916e-116	384.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6489087_2	1267534.KB906758_gene2254	2.218e-127	414.0	COG0823@1|root,COG3828@1|root,COG0823@2|Bacteria,COG3828@2|Bacteria,3Y6DB@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_6489087_1	234267.Acid_3677	1.761e-188	596.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6489087_5	401053.AciPR4_2818	3.719e-65	229.0	COG0591@1|root,COG0591@2|Bacteria,3Y6NZ@57723|Acidobacteria,2JMN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_6495496_0	234267.Acid_7679	5.55e-92	326.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6495496_1	251221.35214645	3.298e-50	184.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
GDHHQS2_k127_6495496_2	864051.BurJ1DRAFT_3700	3.667e-21	109.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
GDHHQS2_k127_6495785_1	1382359.JIAL01000001_gene61	1.042e-113	372.0	COG1484@1|root,COG1484@2|Bacteria,3Y4QK@57723|Acidobacteria,2JNWI@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
GDHHQS2_k127_6495785_0	671143.DAMO_0032	1.469e-172	555.0	COG4584@1|root,COG4584@2|Bacteria,2NRIK@2323|unclassified Bacteria	2|Bacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS2_k127_6496653_1	1380390.JIAT01000009_gene1093	5.158e-112	368.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4CSYM@84995|Rubrobacteria	84995|Rubrobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS2_k127_6496653_0	633149.Bresu_2127	9.677e-222	695.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	-	ko:K15064	ko00627,ko01120,map00627,map01120	-	R09270	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_6506696_4	641491.DND132_3186	4.037e-40	167.0	COG4409@1|root,COG4409@2|Bacteria,1PNKY@1224|Proteobacteria,42YPA@68525|delta/epsilon subdivisions,2WTIT@28221|Deltaproteobacteria,2M7SI@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_6506696_3	314230.DSM3645_24005	6.709e-87	305.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_6506696_0	1267535.KB906767_gene5003	4.043e-244	765.0	COG1574@1|root,COG1574@2|Bacteria,3Y7EK@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_6506696_7	682795.AciX8_1248	1.816e-06	53.0	COG3668@1|root,COG3668@2|Bacteria,3Y8UY@57723|Acidobacteria,2JNNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Plasmid stabilization system	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_6506696_6	388467.A19Y_1069	2.175e-09	61.0	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
GDHHQS2_k127_6506696_5	1089553.Tph_c23990	1.439e-32	138.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,25CH0@186801|Clostridia	186801|Clostridia	H	Pfam:Methyltransf_6	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
GDHHQS2_k127_6506696_1	1123508.JH636439_gene1019	6.463e-179	568.0	COG1063@1|root,COG1063@2|Bacteria,2J0AD@203682|Planctomycetes	203682|Planctomycetes	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_6506696_2	1123368.AUIS01000005_gene309	5.435e-91	316.0	COG2271@1|root,COG2271@2|Bacteria,1QV3V@1224|Proteobacteria	1224|Proteobacteria	G	response to oxidative stress	yaaU	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K08368	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
GDHHQS2_k127_6510287_0	1340493.JNIF01000003_gene3829	0.0	1091.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6510287_5	313596.RB2501_14909	1.782e-121	404.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_6510287_9	1267535.KB906767_gene3783	8.396e-44	170.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria,2JJ6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS2_k127_6510287_3	234267.Acid_0434	7.536e-176	574.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,FAD_oxidored,GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_6510287_10	1267535.KB906767_gene3467	5.611e-42	158.0	COG1366@1|root,COG1366@2|Bacteria,3Y83J@57723|Acidobacteria	57723|Acidobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS2_k127_6510287_6	1340493.JNIF01000003_gene2217	2.802e-74	257.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.3.1.157,2.7.7.13,2.7.7.23,5.4.2.8	ko:K04042,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00416,R00885,R01818,R05332	RC00002,RC00004,RC00166,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GDHHQS2_k127_6510287_4	1123242.JH636435_gene1858	1.336e-134	443.0	COG4409@1|root,COG4409@2|Bacteria,2J4T9@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_6510287_1	1340493.JNIF01000003_gene3902	3.206e-242	775.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6510287_2	1340493.JNIF01000003_gene3903	2.603e-191	606.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6510287_7	1267580.AF6_0987	4.264e-52	199.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,4HG4T@91061|Bacilli,21WXP@150247|Anoxybacillus	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
GDHHQS2_k127_6510287_8	234267.Acid_0941	2.627e-48	173.0	COG5606@1|root,COG5606@2|Bacteria,3Y5KT@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
GDHHQS2_k127_6510287_12	234267.Acid_0940	1.7e-06	50.0	COG4679@1|root,COG4679@2|Bacteria,3Y5UF@57723|Acidobacteria	57723|Acidobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_6510287_11	234267.Acid_0940	1.528e-07	55.0	COG4679@1|root,COG4679@2|Bacteria,3Y5UF@57723|Acidobacteria	57723|Acidobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_6515293_1	234267.Acid_0040	1.092e-176	556.0	COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_6515293_10	1267535.KB906767_gene3052	1.422e-23	108.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Y7@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6515293_3	234267.Acid_7827	8.512e-142	457.0	COG1085@1|root,COG1085@2|Bacteria,3Y3TR@57723|Acidobacteria	57723|Acidobacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
GDHHQS2_k127_6515293_6	309800.C498_01345	9.566e-71	252.0	COG3386@1|root,arCOG05370@2157|Archaea	2157|Archaea	G	SMP-30 Gluconolaconase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
GDHHQS2_k127_6515293_8	1122919.KB905573_gene3576	5.597e-61	218.0	COG1028@1|root,COG1028@2|Bacteria,1TSCT@1239|Firmicutes,4HD4Z@91061|Bacilli,26S0W@186822|Paenibacillaceae	91061|Bacilli	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_6515293_4	234267.Acid_7842	1.345e-111	369.0	COG1273@1|root,COG1273@2|Bacteria,3Y4E7@57723|Acidobacteria	57723|Acidobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS2_k127_6515293_0	234267.Acid_1582	0.0	1041.0	COG2936@1|root,COG2936@2|Bacteria,3Y684@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_6515293_9	1038858.AXBA01000054_gene364	1.403e-29	138.0	COG1807@1|root,COG1807@2|Bacteria,1RIH5@1224|Proteobacteria,2UMSQ@28211|Alphaproteobacteria,3F19B@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6515293_7	886293.Sinac_6613	4.402e-64	248.0	COG1216@1|root,COG1216@2|Bacteria,2IZFD@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_6515293_2	373994.Riv7116_6903	7.734e-158	512.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1HMK8@1161|Nostocales	1117|Cyanobacteria	H	PFAM Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_6515293_5	1340493.JNIF01000002_gene1252	1.343e-78	265.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_6523483_3	1267535.KB906767_gene5042	5.969e-15	83.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZC@57723|Acidobacteria,2JK8R@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6523483_0	1267535.KB906767_gene1814	1.06e-181	601.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria,2JM2Q@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6523483_2	502025.Hoch_2959	1.444e-123	405.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS2_k127_6523483_1	234267.Acid_6265	3.49e-155	516.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6524806_7	1340493.JNIF01000003_gene2881	4.368e-17	91.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria	57723|Acidobacteria	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
GDHHQS2_k127_6524806_1	1267535.KB906767_gene640	6.977e-216	678.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS2_k127_6524806_8	1382303.JPOM01000001_gene2215	0.0007843	43.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,2KFNH@204458|Caulobacterales	204458|Caulobacterales	Q	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
GDHHQS2_k127_6524806_0	234267.Acid_7188	9.533e-253	805.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria	57723|Acidobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
GDHHQS2_k127_6524806_4	234267.Acid_3334	6.274e-67	245.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_6524806_6	1121904.ARBP01000021_gene3593	4.2e-44	181.0	COG3794@1|root,COG3794@2|Bacteria,4NG61@976|Bacteroidetes,47MGM@768503|Cytophagia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6524806_2	1340493.JNIF01000003_gene3848	6.999e-170	538.0	COG0524@1|root,COG0524@2|Bacteria,3Y6VV@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS2_k127_6524806_3	1340493.JNIF01000003_gene3849	5.83e-135	440.0	COG2304@1|root,COG2304@2|Bacteria,3Y6QE@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GDHHQS2_k127_6524806_5	234267.Acid_0295	7.926e-56	205.0	COG1974@1|root,COG1974@2|Bacteria,3Y813@57723|Acidobacteria	57723|Acidobacteria	KT	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6526124_4	234267.Acid_1210	2.336e-67	242.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amino_oxidase,Ank,Ank_2,Ank_3,Ank_4,Ank_5,PSCyt1,Peptidase_C14,Prenyltrans,SQHop_cyclase_C
GDHHQS2_k127_6526124_3	1267535.KB906767_gene4231	1.547e-134	442.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	2|Bacteria	C	Trehalose utilisation	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
GDHHQS2_k127_6526124_5	1123242.JH636434_gene4027	1.623e-42	162.0	COG4886@1|root,COG4886@2|Bacteria,2J0RN@203682|Planctomycetes	203682|Planctomycetes	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
GDHHQS2_k127_6526124_6	1267535.KB906767_gene4319	1.032e-30	130.0	COG2076@1|root,COG2076@2|Bacteria,3Y8G8@57723|Acidobacteria	57723|Acidobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6526124_7	234267.Acid_4551	1.028e-27	118.0	COG2076@1|root,COG2076@2|Bacteria,3Y93B@57723|Acidobacteria	57723|Acidobacteria	P	Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6526124_0	330214.NIDE0577	6.757e-297	930.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
GDHHQS2_k127_6526124_1	530564.Psta_3017	3.755e-278	868.0	COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_6526124_2	1340493.JNIF01000003_gene4600	2.419e-159	512.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_654272_0	296591.Bpro_0276	5.847e-75	256.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2VKQ8@28216|Betaproteobacteria,4AFYK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS2_k127_654272_1	883078.HMPREF9695_04664	3.211e-59	212.0	COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2TSQ8@28211|Alphaproteobacteria,3JSCA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_6543831_0	1089550.ATTH01000001_gene148	6.341e-57	215.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6543831_1	143224.JQMD01000002_gene2981	9.356e-22	103.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_654441_3	886293.Sinac_2838	8.021e-109	359.0	COG0673@1|root,COG0673@2|Bacteria,2IY5Y@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_654441_0	314230.DSM3645_11382	9.78e-193	618.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_654441_2	1123242.JH636434_gene4287	1.196e-119	393.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_654441_1	234267.Acid_1306	1.216e-159	537.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6546925_10	1267535.KB906767_gene4988	1.996e-13	69.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_6546925_7	1037409.BJ6T_37060	4.061e-66	234.0	COG0223@1|root,COG0223@2|Bacteria,1RFNX@1224|Proteobacteria,2VGI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
GDHHQS2_k127_6546925_6	234267.Acid_4857	1.055e-96	329.0	COG0438@1|root,COG0438@2|Bacteria,3Y5Q4@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6546925_1	1267535.KB906767_gene4368	1.288e-158	510.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria	57723|Acidobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_6546925_2	1267535.KB906767_gene2215	4.202e-138	458.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_6546925_9	1340493.JNIF01000003_gene4396	1.522e-28	130.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
GDHHQS2_k127_6546925_0	234267.Acid_6201	2.581e-162	520.0	COG0624@1|root,COG0624@2|Bacteria,3Y3J0@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_6546925_8	1267535.KB906767_gene3039	3.99e-63	219.0	COG0764@1|root,COG0764@2|Bacteria,3Y4CG@57723|Acidobacteria,2JJ97@204432|Acidobacteriia	204432|Acidobacteriia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS2_k127_6546925_4	234267.Acid_6203	2.875e-111	365.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GDHHQS2_k127_6546925_3	234267.Acid_6204	4.014e-113	370.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
GDHHQS2_k127_6546925_5	234267.Acid_6205	1.063e-110	372.0	COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6546925_11	234267.Acid_6206	2.064e-09	63.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
GDHHQS2_k127_6548766_1	234267.Acid_4451	1.186e-188	595.0	COG0673@1|root,COG0673@2|Bacteria,3Y71T@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6548766_3	234267.Acid_1892	1.986e-90	322.0	COG1335@1|root,COG1335@2|Bacteria,3Y67T@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS2_k127_6548766_2	1123242.JH636438_gene5875	2.097e-126	423.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_6548766_4	1340493.JNIF01000003_gene2984	5.109e-26	110.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_6548766_5	234267.Acid_7608	7.417e-14	74.0	COG3316@1|root,COG3316@2|Bacteria,3Y888@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
GDHHQS2_k127_6548766_0	1340493.JNIF01000003_gene3464	1.248e-302	947.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6549103_1	1267535.KB906767_gene1738	2.39e-54	196.0	COG3829@1|root,COG3829@2|Bacteria,3Y6K2@57723|Acidobacteria	57723|Acidobacteria	KT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
GDHHQS2_k127_6549103_0	1340493.JNIF01000004_gene897	5.563e-211	663.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
GDHHQS2_k127_6549103_2	234267.Acid_7365	1.567e-33	139.0	2EQJB@1|root,33I5C@2|Bacteria,3Y5WN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6559727_0	234267.Acid_7074	8.349e-244	758.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria	57723|Acidobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS2_k127_6559727_1	234267.Acid_7073	7.352e-79	269.0	COG0546@1|root,COG0546@2|Bacteria,3Y7CE@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS2_k127_6559727_2	886293.Sinac_0548	9.08e-64	223.0	COG3644@1|root,COG3644@2|Bacteria,2IZT1@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
GDHHQS2_k127_6561666_0	1499967.BAYZ01000153_gene1544	1.27e-70	244.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35
GDHHQS2_k127_6561666_1	1267533.KB906739_gene2502	1.634e-45	179.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	204432|Acidobacteriia	GKT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_6562429_3	234267.Acid_7454	1.255e-60	221.0	COG4786@1|root,COG4786@2|Bacteria,3Y2HI@57723|Acidobacteria	57723|Acidobacteria	N	basal body rod protein	-	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS2_k127_6562429_2	1267535.KB906767_gene3912	3.365e-125	406.0	COG4786@1|root,COG4786@2|Bacteria,3Y3K1@57723|Acidobacteria,2JIER@204432|Acidobacteriia	204432|Acidobacteriia	N	flagellar basal-body rod protein FlgG	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS2_k127_6562429_5	234267.Acid_7452	1.009e-27	124.0	COG1261@1|root,COG1261@2|Bacteria,3Y8G9@57723|Acidobacteria	57723|Acidobacteria	NO	Chaperone for flagella basal body P-ring formation	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
GDHHQS2_k127_6562429_4	234267.Acid_7451	3.76e-60	215.0	COG2063@1|root,COG2063@2|Bacteria,3Y3D6@57723|Acidobacteria	57723|Acidobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
GDHHQS2_k127_6562429_1	234267.Acid_7450	3.933e-138	448.0	COG1706@1|root,COG1706@2|Bacteria,3Y2UQ@57723|Acidobacteria	57723|Acidobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
GDHHQS2_k127_6562429_6	1137799.GZ78_20965	0.0007555	45.0	COG3951@1|root,COG3951@2|Bacteria	2|Bacteria	MNO	Flagellar rod assembly protein muramidase FlgJ	flgJ	GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
GDHHQS2_k127_6562429_0	234267.Acid_0120	1.373e-194	617.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS2_k127_6570071_0	234267.Acid_2982	1.228e-187	605.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6570448_0	1340493.JNIF01000004_gene554	1.348e-101	341.0	COG1052@1|root,COG1052@2|Bacteria,3Y2MD@57723|Acidobacteria	2|Bacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_6570448_1	1340493.JNIF01000004_gene553	9.907e-97	322.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
GDHHQS2_k127_6570448_2	452637.Oter_1874	5.085e-13	81.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6570448_3	1313172.YM304_03450	8.431e-11	72.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	MA20_05265	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_657121_3	1267535.KB906767_gene3353	7.941e-24	101.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS2_k127_657121_1	234267.Acid_3692	7.263e-70	248.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_657121_0	1340493.JNIF01000003_gene4516	3.095e-120	390.0	COG0463@1|root,COG0463@2|Bacteria,3Y34G@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_657121_2	1267535.KB906767_gene2286	7.535e-61	222.0	COG0438@1|root,COG0438@2|Bacteria,3Y7XP@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6575380_1	1267535.KB906767_gene2189	7.024e-57	201.0	28NYH@1|root,2ZBVN@2|Bacteria,3Y4V7@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0403 family	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
GDHHQS2_k127_6575380_2	404589.Anae109_0813	1.131e-34	139.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
GDHHQS2_k127_6575380_0	290397.Adeh_0766	1.962e-126	416.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
GDHHQS2_k127_6575639_0	573370.DMR_p1_00570	6.516e-38	149.0	COG4644@1|root,COG4644@2|Bacteria,1MUIU@1224|Proteobacteria,431XM@68525|delta/epsilon subdivisions,2WWEI@28221|Deltaproteobacteria,2M9ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
GDHHQS2_k127_6575639_2	1122179.KB890420_gene2433	0.0004832	49.0	COG3291@1|root,COG3591@1|root,COG4733@1|root,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4733@2|Bacteria,4NG2K@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
GDHHQS2_k127_6575639_1	1123274.KB899411_gene3195	2.074e-05	58.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Cu_amine_oxidN1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
GDHHQS2_k127_6582362_2	1267534.KB906755_gene4156	6.488e-117	380.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Z2@57723|Acidobacteria,2JMN3@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6582362_1	234267.Acid_4123	2.022e-118	393.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_6582362_7	1340493.JNIF01000003_gene3925	3.542e-36	151.0	COG2062@1|root,COG2062@2|Bacteria,3Y5YQ@57723|Acidobacteria	57723|Acidobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GDHHQS2_k127_6582362_4	1396418.BATQ01000025_gene5258	4.47e-82	286.0	COG0657@1|root,COG0657@2|Bacteria,46ZMC@74201|Verrucomicrobia,2IVRI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS2_k127_6582362_8	1242864.D187_002936	3.473e-35	138.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,42Y4G@68525|delta/epsilon subdivisions,2WTC4@28221|Deltaproteobacteria,2YV68@29|Myxococcales	28221|Deltaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_6582362_0	452637.Oter_0253	2.058e-121	406.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_6582362_9	237368.SCABRO_01795	1.264e-34	151.0	COG0457@1|root,COG0498@1|root,COG0457@2|Bacteria,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,PALP,TIR_2,TPR_12,TPR_8
GDHHQS2_k127_6582362_6	234267.Acid_5541	4.855e-65	230.0	COG0030@1|root,COG0030@2|Bacteria,3Y3RQ@57723|Acidobacteria	57723|Acidobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS2_k127_6582362_10	204669.Acid345_3851	2.858e-26	118.0	COG5662@1|root,COG5662@2|Bacteria,3Y4JS@57723|Acidobacteria,2JJ7U@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_6582362_5	1340493.JNIF01000003_gene2787	5.231e-75	258.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_6582362_3	1123278.KB893590_gene5410	2.287e-91	335.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_6584254_3	234267.Acid_2710	5.258e-05	49.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,3Y2UJ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
GDHHQS2_k127_6584254_1	234267.Acid_2709	2.764e-32	139.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	damX	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_10,SPOR
GDHHQS2_k127_6584254_2	1410613.JNKF01000010_gene628	7.428e-15	86.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,2FP40@200643|Bacteroidia	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_6584254_0	1340493.JNIF01000004_gene405	4.018e-40	160.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6588493_2	1340493.JNIF01000004_gene1083	6.398e-86	292.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6588493_6	570268.ANBB01000056_gene56	1.651e-23	108.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4EIS5@85012|Streptosporangiales	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
GDHHQS2_k127_6588493_5	2002.JOEQ01000087_gene566	6.731e-32	142.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TIR_2,WD40
GDHHQS2_k127_6588493_3	1123277.KB893184_gene4089	4.951e-75	258.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,47NR0@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS2_k127_6588493_1	1267535.KB906767_gene4077	1.339e-142	464.0	COG2239@1|root,COG2239@2|Bacteria,3Y3WD@57723|Acidobacteria,2JI0X@204432|Acidobacteriia	204432|Acidobacteriia	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
GDHHQS2_k127_6588493_0	234267.Acid_6728	5.567e-191	603.0	COG1914@1|root,COG1914@2|Bacteria,3Y3EU@57723|Acidobacteria	57723|Acidobacteria	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS2_k127_6588493_9	314278.NB231_02733	6.098e-08	57.0	COG1598@1|root,COG1598@2|Bacteria,1N00D@1224|Proteobacteria,1TK9Z@1236|Gammaproteobacteria,1X0XS@135613|Chromatiales	135613|Chromatiales	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
GDHHQS2_k127_6588493_7	1198452.Jab_1c12200	2.892e-14	77.0	COG1598@1|root,COG1598@2|Bacteria,1N00D@1224|Proteobacteria,2VXGB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB,HicB_lk_antitox
GDHHQS2_k127_6588493_10	686340.Metal_2809	3.194e-07	55.0	2DS0K@1|root,33DZ7@2|Bacteria,1NKVW@1224|Proteobacteria,1SGDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_6588493_8	1267535.KB906767_gene4499	1.294e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_6588493_4	344747.PM8797T_07699	4.262e-57	205.0	COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes	203682|Planctomycetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
GDHHQS2_k127_6588620_0	234267.Acid_7665	1.849e-177	577.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_6588620_1	234267.Acid_7666	7.903e-147	479.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6589542_0	518766.Rmar_1703	2.129e-136	478.0	COG0784@1|root,COG3292@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
GDHHQS2_k127_6589542_1	1123242.JH636435_gene2360	3.269e-130	431.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_6592925_0	234267.Acid_7252	0.0	1024.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS2_k127_6595395_0	627192.SLG_30030	3.473e-157	534.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1NTSI@1224|Proteobacteria,2UNXM@28211|Alphaproteobacteria,2K1IF@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6595395_1	497964.CfE428DRAFT_5426	1.515e-139	455.0	COG1680@1|root,COG1680@2|Bacteria,46WGY@74201|Verrucomicrobia	74201|Verrucomicrobia	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6598787_0	1340493.JNIF01000003_gene4764	5.84e-174	563.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6598787_1	1210884.HG799466_gene12570	2.838e-123	402.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6598787_2	204669.Acid345_1384	7.954e-116	376.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_6600195_2	234267.Acid_5744	1.86e-144	473.0	COG2304@1|root,COG2304@2|Bacteria,3Y6TM@57723|Acidobacteria	57723|Acidobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
GDHHQS2_k127_6600195_3	1267535.KB906767_gene3460	3.145e-118	386.0	COG1721@1|root,COG1721@2|Bacteria,3Y6DV@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_6600195_1	234267.Acid_5746	3.899e-149	477.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria	57723|Acidobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_6600195_4	234267.Acid_1195	3.076e-50	188.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria	57723|Acidobacteria	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GDHHQS2_k127_6600195_0	1267534.KB906754_gene3673	4.007e-211	676.0	28HBM@1|root,2Z7NK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6600195_5	1267535.KB906767_gene3571	2.098e-31	131.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6602467_1	1340493.JNIF01000003_gene1631	4.693e-41	169.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GDHHQS2_k127_6602467_4	1121385.AQXW01000004_gene1098	0.0003054	47.0	2E4Q9@1|root,32ZIV@2|Bacteria,2II59@201174|Actinobacteria,1ZW8G@145357|Dermacoccaceae	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
GDHHQS2_k127_6602467_0	1340493.JNIF01000003_gene2297	0.0	1141.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,3Y61D@57723|Acidobacteria	57723|Acidobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
GDHHQS2_k127_6602467_3	1267533.KB906742_gene696	4.392e-13	73.0	COG4775@1|root,COG4775@2|Bacteria,3Y2NP@57723|Acidobacteria,2JIUP@204432|Acidobacteriia	204432|Acidobacteriia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6607391_0	1340493.JNIF01000004_gene448	4.16e-275	855.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_6607391_2	880070.Cycma_2424	2.456e-117	384.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47TIE@768503|Cytophagia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_6607391_1	234267.Acid_3675	1.753e-148	482.0	COG1921@1|root,COG1921@2|Bacteria,3Y39V@57723|Acidobacteria	57723|Acidobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS2_k127_6607391_3	234267.Acid_0334	5.325e-79	273.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
GDHHQS2_k127_6613249_0	1267535.KB906767_gene3106	5.746e-126	422.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6614218_0	861299.J421_6226	1.21e-65	235.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6614218_1	1379270.AUXF01000004_gene2987	9.719e-55	199.0	COG4247@1|root,COG4247@2|Bacteria	2|Bacteria	I	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	phy	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	NHL,Phytase
GDHHQS2_k127_6615878_2	1121012.AUKX01000001_gene1196	1.132e-06	62.0	2BZ4R@1|root,3344Z@2|Bacteria,4NX0J@976|Bacteroidetes,1I7U3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6615878_1	234267.Acid_3872	6.293e-44	162.0	2CIU6@1|root,32S8H@2|Bacteria,3Y8IT@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6615878_0	234267.Acid_3874	2.547e-120	389.0	COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria	57723|Acidobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS2_k127_6616829_0	1210884.HG799464_gene11164	5.731e-120	405.0	COG0551@1|root,COG0551@2|Bacteria,2IXB2@203682|Planctomycetes	203682|Planctomycetes	L	Ca-dependent carbohydrate-binding module xylan-binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_6616829_1	521674.Plim_0128	4.08e-18	88.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_6616845_5	1340493.JNIF01000004_gene772	1.33e-20	91.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6616845_1	1267535.KB906767_gene348	3.418e-157	503.0	COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria,2JIFQ@204432|Acidobacteriia	204432|Acidobacteriia	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
GDHHQS2_k127_6616845_2	143224.JQMD01000002_gene121	2.701e-98	338.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,1HZ00@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6616845_4	1340493.JNIF01000003_gene2955	2.871e-22	102.0	2FIG5@1|root,34A8B@2|Bacteria,3Y8GN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6616845_0	234267.Acid_4059	2.761e-251	806.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6616845_3	1340493.JNIF01000004_gene556	2.253e-94	316.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6629156_9	290317.Cpha266_2183	6.46e-08	63.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_6629156_1	1267535.KB906767_gene2769	1.594e-222	716.0	COG0577@1|root,COG0577@2|Bacteria,3Y6DT@57723|Acidobacteria,2JKDM@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6629156_6	84531.JMTZ01000031_gene109	8.061e-42	157.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,1T116@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_6629156_5	1267535.KB906767_gene2981	7.495e-49	182.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	psbV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02720	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	iJN678.psbV	Cytochrom_C,Cytochrom_C550,Cytochrom_CIII,Cytochrome_C7
GDHHQS2_k127_6629156_0	1340493.JNIF01000004_gene435	4.308e-246	772.0	COG2303@1|root,COG2303@2|Bacteria,3Y6FS@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_6629156_4	478741.JAFS01000001_gene1893	1.18e-75	267.0	COG0707@1|root,COG0707@2|Bacteria,46SRU@74201|Verrucomicrobia,37G9Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
GDHHQS2_k127_6629156_2	234267.Acid_3990	4.116e-108	359.0	COG2755@1|root,COG2755@2|Bacteria,3Y4BD@57723|Acidobacteria	57723|Acidobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_6629156_7	1267535.KB906767_gene1286	5.186e-38	152.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_6629156_3	670307.HYPDE_29643	1.067e-89	303.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3N7HK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_6630386_4	1108045.GORHZ_066_00010	1.308e-05	52.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS2_k127_6630386_3	266117.Rxyl_2863	4.303e-19	92.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
GDHHQS2_k127_6630386_0	1340493.JNIF01000004_gene779	3.063e-86	305.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_6630386_1	234267.Acid_0955	7.302e-65	230.0	COG1385@1|root,COG1385@2|Bacteria,3Y3XJ@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GDHHQS2_k127_6630386_2	234267.Acid_1266	1.217e-23	103.0	COG1562@1|root,COG1562@2|Bacteria,3Y3YX@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
GDHHQS2_k127_6631886_1	675635.Psed_3943	1.515e-63	227.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4DYUN@85010|Pseudonocardiales	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
GDHHQS2_k127_6631886_0	35754.JNYJ01000005_gene5643	1.203e-172	556.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_6635583_2	234267.Acid_5912	4.608e-38	147.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS2_k127_6635583_4	525368.HMPREF0591_4418	3.208e-07	58.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria,23BD7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_6635583_3	1122239.AULS01000001_gene1711	8.886e-08	58.0	COG4118@1|root,COG4118@2|Bacteria,2GQNI@201174|Actinobacteria,4FSWS@85023|Microbacteriaceae	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_6635583_1	1267535.KB906767_gene2645	5.552e-62	222.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria	57723|Acidobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS2_k127_6635583_0	886293.Sinac_7090	8.357e-106	359.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6644318_0	344747.PM8797T_11626	7.371e-131	434.0	2EZBQ@1|root,33SH2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6644318_3	1123399.AQVE01000001_gene654	5.388e-15	78.0	COG4456@1|root,COG4456@2|Bacteria	2|Bacteria	-	-	vapB1	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
GDHHQS2_k127_6644318_2	1340493.JNIF01000004_gene282	4.085e-57	205.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
GDHHQS2_k127_6644318_1	1267533.KB906734_gene4361	6.567e-107	352.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria,2JP12@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_6648984_3	1340493.JNIF01000003_gene1750	1.621e-145	470.0	COG0183@1|root,COG0183@2|Bacteria,3Y7RP@57723|Acidobacteria	57723|Acidobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_6648984_6	1340493.JNIF01000003_gene3680	5.401e-104	356.0	COG1792@1|root,COG1792@2|Bacteria,3Y3CK@57723|Acidobacteria	57723|Acidobacteria	M	Rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS2_k127_6648984_10	1267535.KB906767_gene755	1.565e-46	183.0	2CM1I@1|root,32SDF@2|Bacteria,3Y571@57723|Acidobacteria	57723|Acidobacteria	S	shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
GDHHQS2_k127_6648984_2	401053.AciPR4_0883	2.522e-172	560.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria,2JHRD@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS2_k127_6648984_4	234267.Acid_4179	2.333e-128	421.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria	57723|Acidobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_6648984_8	754477.Q7C_590	2.043e-96	347.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales	72273|Thiotrichales	J	ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
GDHHQS2_k127_6648984_11	1168059.KB899087_gene3133	6.743e-13	69.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_6648984_9	234267.Acid_4580	9.14e-56	203.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
GDHHQS2_k127_6648984_7	234267.Acid_4580	7.492e-103	341.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
GDHHQS2_k127_6648984_13	1340493.JNIF01000003_gene1928	1.741e-06	53.0	COG1629@1|root,COG1629@2|Bacteria,3Y2FQ@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6648984_0	234267.Acid_6875	0.0	1034.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6648984_12	1382359.JIAL01000001_gene1577	2.158e-07	60.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
GDHHQS2_k127_6648984_1	663610.JQKO01000008_gene201	6.64e-317	978.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,3N9Y2@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	dihydroxy-acid dehydratase activity	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_6648984_5	1340493.JNIF01000003_gene2335	2.94e-111	366.0	COG1082@1|root,COG1082@2|Bacteria,3Y7IK@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6653468_2	243231.GSU1638	6.03e-17	87.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
GDHHQS2_k127_6653468_0	1340493.JNIF01000003_gene2879	5.565e-57	203.0	COG0629@1|root,COG0629@2|Bacteria,3Y4D2@57723|Acidobacteria	57723|Acidobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS2_k127_6653468_1	1532558.JL39_21870	3.793e-25	111.0	COG1321@1|root,COG1321@2|Bacteria,1N90S@1224|Proteobacteria,2UES8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,LexA_DNA_bind
GDHHQS2_k127_6659010_2	1454004.AW11_03240	2.731e-24	121.0	COG3210@1|root,COG3210@2|Bacteria,1QVC2@1224|Proteobacteria,2VSG1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act,VPEP
GDHHQS2_k127_6659010_0	234267.Acid_6881	8.578e-100	361.0	COG1361@1|root,COG3534@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3534@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,DUF4347,Glyco_hydro_43,He_PIG,P_proprotein,Peptidase_S8,TIG
GDHHQS2_k127_6659010_1	1267535.KB906767_gene3133	7.517e-68	244.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6661520_0	405948.SACE_5008	1.858e-75	263.0	28I5G@1|root,2Z88U@2|Bacteria,2IBY7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6661520_1	63737.Npun_R5915	4.854e-33	138.0	COG2837@1|root,COG2837@2|Bacteria,1G5Q6@1117|Cyanobacteria,1HSP0@1161|Nostocales	1117|Cyanobacteria	C	TIGRFAM Dyp-type peroxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Dyp_perox
GDHHQS2_k127_6662170_0	1054213.HMPREF9946_00179	1.12e-65	239.0	COG0477@1|root,COG2814@2|Bacteria,1R7EW@1224|Proteobacteria,2TXMM@28211|Alphaproteobacteria,2JW1M@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6662170_1	713587.THITH_04565	7.662e-41	154.0	COG1598@1|root,COG1598@2|Bacteria,1N00D@1224|Proteobacteria,1TK9Z@1236|Gammaproteobacteria,1X0XS@135613|Chromatiales	135613|Chromatiales	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
GDHHQS2_k127_6662170_2	987059.RBXJA2T_03186	1.569e-08	56.0	2DS0K@1|root,33DZ7@2|Bacteria,1NKVW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_6664347_0	401053.AciPR4_2317	2.129e-58	224.0	COG2132@1|root,COG2132@2|Bacteria,3Y65V@57723|Acidobacteria,2JMCT@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM multicopper oxidase type 2	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GDHHQS2_k127_6664347_1	136993.KB900626_gene2783	9.215e-44	172.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,2U42A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
GDHHQS2_k127_6671827_0	234267.Acid_1306	1.079e-185	621.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6671827_1	1407650.BAUB01000001_gene44	2.876e-69	254.0	COG0591@1|root,COG0591@2|Bacteria,1G3Y2@1117|Cyanobacteria,1H418@1129|Synechococcus	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS2_k127_6671827_2	1123060.JONP01000001_gene1583	5.878e-37	152.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2JPJS@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_667185_0	1340493.JNIF01000003_gene4693	2.717e-06	60.0	COG0652@1|root,COG5563@1|root,COG0652@2|Bacteria,COG5563@2|Bacteria,3Y8DZ@57723|Acidobacteria	57723|Acidobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS2_k127_6673927_0	1382359.JIAL01000001_gene2838	1.126e-118	387.0	KOG1573@1|root,2Z822@2|Bacteria,3Y3AN@57723|Acidobacteria,2JKNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Myo-inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
GDHHQS2_k127_6673927_2	1278073.MYSTI_06086	4.744e-51	188.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,2YV2X@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS2_k127_6673927_1	1121481.AUAS01000005_gene1845	7.128e-118	392.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47ND1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6677492_3	1340493.JNIF01000003_gene2327	2.132e-37	143.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
GDHHQS2_k127_6677492_1	1340493.JNIF01000003_gene2326	3.905e-168	550.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_6677492_0	1340493.JNIF01000003_gene2325	1.462e-211	663.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	macB_1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6677492_2	1340493.JNIF01000003_gene2324	7.432e-168	546.0	COG1538@1|root,COG1538@2|Bacteria,3Y7Q2@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_6677492_4	1123242.JH636435_gene2360	2.141e-06	53.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GDHHQS2_k127_6678487_3	1501230.ET33_29155	1.289e-05	53.0	COG4675@1|root,COG4675@2|Bacteria,1V6CH@1239|Firmicutes,4HK20@91061|Bacilli,26YUI@186822|Paenibacillaceae	91061|Bacilli	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
GDHHQS2_k127_6678487_0	886293.Sinac_0696	2.236e-157	507.0	COG3119@1|root,COG3119@2|Bacteria,2J2HU@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6678487_2	234267.Acid_3567	1.391e-103	345.0	COG0739@1|root,COG0739@2|Bacteria,3Y3N4@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_6678487_1	1340493.JNIF01000003_gene4604	1.923e-111	370.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
GDHHQS2_k127_6688851_8	234267.Acid_6247	9.125e-58	212.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6688851_2	234267.Acid_0194	8.36e-159	537.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6688851_9	1267533.KB906736_gene1100	6.41e-38	147.0	29WUP@1|root,30IG4@2|Bacteria,3Y82K@57723|Acidobacteria	57723|Acidobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6688851_6	880073.Calab_1912	2.088e-68	244.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_6688851_7	1267533.KB906736_gene1169	4.789e-68	255.0	COG2208@1|root,COG3250@1|root,COG2208@2|Bacteria,COG3250@2|Bacteria,3Y3S8@57723|Acidobacteria,2JI1T@204432|Acidobacteriia	2|Bacteria	GKT	Sigma factor PP2C-like phosphatases	prpB12	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_6688851_11	565033.GACE_0089	8.806e-35	138.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_6688851_15	204669.Acid345_1733	5.182e-11	72.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	2|Bacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_6688851_16	234267.Acid_7874	1.748e-05	50.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_6688851_1	1267535.KB906767_gene2162	7.671e-235	737.0	COG1069@1|root,COG1069@2|Bacteria,3Y3B6@57723|Acidobacteria,2JI84@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Carbohydrate kinase	-	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_6688851_5	1396141.BATP01000019_gene1647	7.576e-73	248.0	COG3832@1|root,COG3832@2|Bacteria,46XRK@74201|Verrucomicrobia,2IWFC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_6688851_10	1267535.KB906767_gene4024	6.533e-37	145.0	COG0640@1|root,COG0640@2|Bacteria,3Y7UZ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_6688851_14	1267534.KB906757_gene993	7.525e-13	76.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	MA20_35850	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6688851_13	1267534.KB906757_gene993	1.99e-13	74.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	MA20_35850	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6688851_12	929562.Emtol_1728	1.321e-29	125.0	COG1999@1|root,COG1999@2|Bacteria,4NMTA@976|Bacteroidetes,47Q9J@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS2_k127_6688851_4	497964.CfE428DRAFT_0984	1.369e-76	269.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6688851_0	234267.Acid_4918	6.87e-306	949.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
GDHHQS2_k127_6688851_3	234267.Acid_6834	1.917e-84	290.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6692794_1	9258.ENSOANP00000025144	4.694e-05	49.0	COG0457@1|root,KOG0548@2759|Eukaryota,39SZH@33154|Opisthokonta,3BF8D@33208|Metazoa,3CX0N@33213|Bilateria,48CMA@7711|Chordata,495ZT@7742|Vertebrata,3JNKQ@40674|Mammalia	33208|Metazoa	O	tetratricopeptide repeat	TTC31	-	-	-	-	-	-	-	-	-	-	-	RRM_1,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_6692794_0	234267.Acid_3066	2.293e-304	974.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6693827_0	330214.NIDE3386	2.809e-175	559.0	COG4198@1|root,COG4198@2|Bacteria,3J0IE@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GDHHQS2_k127_6693827_2	635013.TherJR_0336	1.518e-50	185.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,26152@186807|Peptococcaceae	186801|Clostridia	S	pfam ammecr1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
GDHHQS2_k127_6693827_1	330214.NIDE3385	7.315e-157	502.0	COG0142@1|root,COG0142@2|Bacteria,3J0H0@40117|Nitrospirae	40117|Nitrospirae	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_6693827_3	330214.NIDE3384	5.854e-08	55.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,3J0SV@40117|Nitrospirae	40117|Nitrospirae	C	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS2_k127_6697397_0	234267.Acid_0841	1.419e-268	837.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_6697397_1	1210884.HG799465_gene11824	5.935e-246	764.0	COG2960@1|root,COG2960@2|Bacteria,2IXW9@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS2_k127_6697397_2	344747.PM8797T_27317	3.291e-100	338.0	COG0673@1|root,COG0673@2|Bacteria,2J1QN@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_670035_1	1267535.KB906767_gene5096	2.859e-62	215.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria,2JI2H@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_670035_0	1267535.KB906767_gene5095	3.918e-136	442.0	COG2957@1|root,COG2957@2|Bacteria,3Y2W5@57723|Acidobacteria,2JIKF@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
GDHHQS2_k127_670035_2	1403819.BATR01000018_gene603	2.248e-51	188.0	COG2010@1|root,COG2010@2|Bacteria,46TII@74201|Verrucomicrobia,2IV5F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6706712_1	1340493.JNIF01000004_gene614	9.566e-102	335.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6706712_2	1267533.KB906735_gene4694	4.572e-66	231.0	COG1853@1|root,COG1853@2|Bacteria,3Y51K@57723|Acidobacteria,2JMFE@204432|Acidobacteriia	204432|Acidobacteriia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS2_k127_6706712_0	234267.Acid_7026	3.24e-104	357.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6709870_2	1340493.JNIF01000003_gene1908	4.621e-28	120.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
GDHHQS2_k127_6709870_1	1340493.JNIF01000003_gene1909	1.862e-75	267.0	COG4585@1|root,COG4585@2|Bacteria,3Y8CF@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
GDHHQS2_k127_6709870_0	1267535.KB906767_gene5245	1.65e-157	523.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6713192_8	1038862.KB893837_gene1626	1.171e-09	63.0	COG3668@1|root,COG3668@2|Bacteria,1NE95@1224|Proteobacteria,2UICW@28211|Alphaproteobacteria,3K20C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_6713192_0	1123248.KB893381_gene962	6.492e-246	796.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4P2AE@976|Bacteroidetes	976|Bacteroidetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
GDHHQS2_k127_6713192_2	234267.Acid_2222	7.697e-146	472.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_6713192_4	583355.Caka_0226	2.793e-121	396.0	COG1028@1|root,COG1028@2|Bacteria,46U4E@74201|Verrucomicrobia,3K7SN@414999|Opitutae	414999|Opitutae	IQ	short-chain dehydrogenase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_6713192_3	339670.Bamb_4792	5.201e-125	415.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,1K6IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6713192_5	1337936.IJ00_07850	1.145e-110	378.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
GDHHQS2_k127_6713192_7	28072.Nos7524_5376	3.834e-27	120.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HMSA@1161|Nostocales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS2_k127_6713192_1	1183438.GKIL_1818	1.626e-199	666.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Formyl_trans_N,Methyltransf_12,PP-binding,PilZ
GDHHQS2_k127_6713192_6	1340493.JNIF01000003_gene4693	3.291e-89	304.0	COG0652@1|root,COG5563@1|root,COG0652@2|Bacteria,COG5563@2|Bacteria,3Y8DZ@57723|Acidobacteria	57723|Acidobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
GDHHQS2_k127_6713323_0	234267.Acid_7841	2.286e-190	618.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6713323_1	1267534.KB906754_gene3169	2.311e-37	154.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	aglU	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Trans_reg_C,WD40
GDHHQS2_k127_6720716_3	1267535.KB906767_gene3771	1.011e-138	450.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria,2JIZB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6720716_2	1340493.JNIF01000004_gene758	8.837e-140	463.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
GDHHQS2_k127_6720716_1	1267535.KB906767_gene3665	5.568e-168	544.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,AP_endonuc_2_N,VCBS
GDHHQS2_k127_6720716_0	234267.Acid_1065	1.955e-179	566.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria	57723|Acidobacteria	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS2_k127_6720716_6	234267.Acid_1066	1.898e-50	190.0	28MK6@1|root,33VBX@2|Bacteria,3Y7JM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6720716_5	1340493.JNIF01000004_gene910	4.05e-65	237.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS2_k127_6720716_4	504487.JCM19302_3590	1.505e-101	344.0	COG2271@1|root,COG2271@2|Bacteria,4NGCR@976|Bacteroidetes,1HWZ4@117743|Flavobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6720716_9	521098.Aaci_0942	1.961e-05	53.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS2_k127_6720716_8	1434325.AZQN01000001_gene38	3.595e-10	63.0	COG2271@1|root,COG2271@2|Bacteria,4NGCR@976|Bacteroidetes,47JNU@768503|Cytophagia	976|Bacteroidetes	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6720716_7	234267.Acid_6265	1.059e-49	179.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6723692_0	1122604.JONR01000015_gene125	1.018e-232	738.0	COG0154@1|root,COG0154@2|Bacteria	2|Bacteria	J	amidase activity	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,SLH
GDHHQS2_k127_6726034_3	234267.Acid_0643	8.323e-37	145.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_6726034_1	861299.J421_6284	7.485e-78	269.0	COG4242@1|root,COG4242@2|Bacteria,1ZTBM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS2_k127_6726034_0	1340493.JNIF01000003_gene1928	8.653e-276	887.0	COG1629@1|root,COG1629@2|Bacteria,3Y2FQ@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6726034_2	234267.Acid_4750	3.798e-40	153.0	COG1917@1|root,COG1917@2|Bacteria,3Y5JM@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_6726273_1	1340493.JNIF01000003_gene1927	4.178e-105	351.0	COG4932@1|root,COG4932@2|Bacteria,3Y6EM@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6726273_7	749414.SBI_08688	5.469e-11	76.0	COG0596@1|root,COG0596@2|Bacteria,2I96Q@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_6726273_2	1403819.BATR01000135_gene4814	2.136e-71	263.0	COG4409@1|root,COG4409@2|Bacteria,46WX2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GDHHQS2_k127_6726273_0	234267.Acid_6601	1.358e-162	545.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,RibD_C,SpoIIE
GDHHQS2_k127_6726273_5	941449.dsx2_2106	1.772e-58	217.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2M80N@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS2_k127_6726273_3	1487923.DP73_10970	7.166e-67	239.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS2_k127_6726273_6	596151.DesfrDRAFT_3871	3.039e-55	218.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2M80N@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GDHHQS2_k127_6726273_4	1304284.L21TH_1894	5.227e-66	252.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_6728202_1	234267.Acid_7706	5.588e-79	274.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_7706|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6728202_0	234267.Acid_0811	1.464e-111	369.0	COG1082@1|root,COG1082@2|Bacteria,3Y88X@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6732502_1	1267535.KB906767_gene1082	2.8e-59	215.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat,TonB_dep_Rec
GDHHQS2_k127_6732502_3	1340493.JNIF01000003_gene2321	3.555e-13	75.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6732502_2	1123487.KB892834_gene2888	1.302e-55	201.0	COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,2VR68@28216|Betaproteobacteria,2KWFZ@206389|Rhodocyclales	206389|Rhodocyclales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_6732502_0	1123487.KB892834_gene2887	1.213e-178	576.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VNMX@28216|Betaproteobacteria,2KUGJ@206389|Rhodocyclales	206389|Rhodocyclales	I	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
GDHHQS2_k127_6742781_2	861299.J421_5614	7.742e-76	263.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GDHHQS2_k127_6742781_0	926566.Terro_1216	5.019e-279	884.0	COG2183@1|root,COG2183@2|Bacteria,3Y2QM@57723|Acidobacteria,2JIB9@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA binding	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GDHHQS2_k127_6742781_7	864051.BurJ1DRAFT_1921	3.222e-28	123.0	2C73B@1|root,330Z7@2|Bacteria,1N4FW@1224|Proteobacteria,2W6GV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6742781_3	1110502.TMO_2894	6.722e-70	249.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2TS7X@28211|Alphaproteobacteria,2JSRS@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_6742781_1	1123508.JH636439_gene959	1.541e-235	744.0	COG2936@1|root,COG2936@2|Bacteria,2IY51@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_6742781_5	880073.Calab_1890	2.368e-29	123.0	COG2172@1|root,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
GDHHQS2_k127_6742781_6	518766.Rmar_2330	3.864e-29	120.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_6742781_4	518766.Rmar_0663	1.158e-51	208.0	COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes	976|Bacteroidetes	KT	PFAM Stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_6742781_8	1220534.B655_1282	1.493e-18	100.0	COG2208@1|root,arCOG06893@2157|Archaea,2Y2MD@28890|Euryarchaeota,23PHZ@183925|Methanobacteria	183925|Methanobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,SpoIIE
GDHHQS2_k127_6752508_3	1340493.JNIF01000003_gene1862	8.005e-38	143.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_6752508_1	1340493.JNIF01000003_gene2088	3.423e-320	1005.0	COG4772@1|root,COG4772@2|Bacteria,3Y47K@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_6752508_2	1267535.KB906767_gene220	9.939e-77	271.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria,2JKWG@204432|Acidobacteriia	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS2_k127_6752508_0	234267.Acid_5869	0.0	1041.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6752508_4	1306174.JODP01000013_gene7620	8.253e-38	147.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_6755507_3	159087.Daro_1851	1.204e-36	147.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KYCC@206389|Rhodocyclales	206389|Rhodocyclales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS2_k127_6755507_1	1380355.JNIJ01000070_gene5806	3.3e-94	319.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2U0H3@28211|Alphaproteobacteria,3JR1E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	2.7.10.2,3.3.2.9	ko:K01253,ko:K08253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GDHHQS2_k127_6755507_2	948106.AWZT01000025_gene4809	2.147e-65	229.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2WH63@28216|Betaproteobacteria,1KII6@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_6755507_0	240292.Ava_4664	6.363e-267	843.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1HIIK@1161|Nostocales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GDHHQS2_k127_6768861_1	293826.Amet_3891	7.558e-95	325.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,36DMW@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
GDHHQS2_k127_6768861_0	639030.JHVA01000001_gene1797	8.595e-275	883.0	COG1629@1|root,COG1629@2|Bacteria,3Y39E@57723|Acidobacteria,2JIU9@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_677506_0	234267.Acid_5623	1.76e-172	557.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_677506_1	234267.Acid_1399	4.212e-114	379.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
GDHHQS2_k127_6775880_0	278963.ATWD01000001_gene2919	8.463e-79	285.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6776966_4	102129.Lepto7375DRAFT_2755	5.157e-14	83.0	COG3170@1|root,COG3170@2|Bacteria,1GAGM@1117|Cyanobacteria	1117|Cyanobacteria	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
GDHHQS2_k127_6776966_0	234267.Acid_1474	1.053e-115	385.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6776966_1	234267.Acid_1473	9.246e-115	384.0	COG0477@1|root,COG2814@2|Bacteria,3Y99X@57723|Acidobacteria	57723|Acidobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS2_k127_6776966_3	1144275.COCOR_07802	5.334e-27	121.0	2C80W@1|root,330EI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6776966_2	1144275.COCOR_07801	4.131e-78	281.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42WVB@68525|delta/epsilon subdivisions,2WT41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6776966_6	1121127.JAFA01000045_gene6763	0.000148	53.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria,1K1TE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
GDHHQS2_k127_6780379_4	1340493.JNIF01000004_gene939	1.699e-10	62.0	COG0460@1|root,COG0460@2|Bacteria,3Y2VY@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS2_k127_6780379_1	234267.Acid_0525	6.456e-63	225.0	COG4798@1|root,COG4798@2|Bacteria	2|Bacteria	E	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FAD_binding_4,Methyltransf_11,Methyltransf_25,Methyltransf_31,SAM_MT
GDHHQS2_k127_6780379_0	1267535.KB906767_gene626	2.043e-147	472.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria,2JI3W@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS2_k127_6780379_2	1122919.KB905549_gene1984	2.776e-49	193.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,26QAN@186822|Paenibacillaceae	91061|Bacilli	S	Zn-dependent hydrolases, including glyoxylases	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_6780379_3	234267.Acid_4090	3.682e-40	153.0	COG1187@1|root,COG1187@2|Bacteria,3Y6Y9@57723|Acidobacteria	57723|Acidobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_6782415_0	1123508.JH636444_gene5165	6.811e-97	330.0	COG1073@1|root,COG1073@2|Bacteria,2J53C@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6782415_1	388467.A19Y_3368	5.62e-60	220.0	28J0S@1|root,2Z8XX@2|Bacteria,1G3N4@1117|Cyanobacteria,1HE4I@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6787247_4	344747.PM8797T_10979	2.827e-15	79.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_6787247_2	1340493.JNIF01000004_gene241	5.514e-50	188.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria	57723|Acidobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_6787247_0	1267535.KB906767_gene2507	6.287e-278	885.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS2_k127_6787247_1	1267535.KB906767_gene2508	1.272e-69	250.0	COG1597@1|root,COG1597@2|Bacteria,3Y58A@57723|Acidobacteria,2JP23@204432|Acidobacteriia	204432|Acidobacteriia	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS2_k127_6787247_3	234267.Acid_2715	1.397e-22	111.0	COG1988@1|root,COG1988@2|Bacteria,3Y305@57723|Acidobacteria	57723|Acidobacteria	S	membrane-bound metal-dependent hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS2_k127_67933_4	1340493.JNIF01000004_gene597	1.92e-14	75.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_67933_2	1267535.KB906767_gene1540	6.465e-23	103.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_67933_5	401053.AciPR4_0638	5.411e-12	72.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Y0@57723|Acidobacteria,2JIYU@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_67933_0	278963.ATWD01000001_gene1304	0.0	1039.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_67933_1	204669.Acid345_4148	4.944e-38	149.0	COG2944@1|root,COG2944@2|Bacteria,3Y8RN@57723|Acidobacteria,2JNU8@204432|Acidobacteriia	204432|Acidobacteriia	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
GDHHQS2_k127_67933_3	204669.Acid345_4147	1.456e-15	76.0	2D16E@1|root,32NB1@2|Bacteria,3Y945@57723|Acidobacteria,2JNQE@204432|Acidobacteriia	204432|Acidobacteriia	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
GDHHQS2_k127_6800158_1	545276.KB898727_gene497	3.211e-13	81.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales	135613|Chromatiales	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
GDHHQS2_k127_6800158_0	234267.Acid_1288	1.497e-50	181.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS2_k127_6805066_0	265072.Mfla_0887	0.0	1800.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
GDHHQS2_k127_6805433_2	795359.TOPB45_0383	3.201e-28	124.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS2_k127_6805433_3	215803.DB30_2276	5.706e-28	124.0	2EDTI@1|root,337NU@2|Bacteria,1Q2MU@1224|Proteobacteria,4388F@68525|delta/epsilon subdivisions,2X3I4@28221|Deltaproteobacteria,2YW70@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6805433_0	518766.Rmar_2102	4.84e-181	586.0	COG0464@1|root,COG0464@2|Bacteria,4P1Y0@976|Bacteroidetes,1FIZT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_6805433_1	234267.Acid_0200	2.376e-109	362.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6809052_2	1340493.JNIF01000003_gene3464	5.907e-157	524.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6809052_3	1267535.KB906767_gene1439	7.664e-07	57.0	COG2442@1|root,COG2442@2|Bacteria,3Y8U9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_6809052_1	682795.AciX8_0952	4.111e-249	805.0	COG1629@1|root,COG4771@2|Bacteria,3Y9DR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6809052_0	1340493.JNIF01000003_gene4196	1.55e-291	915.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_6815558_0	497964.CfE428DRAFT_2360	6.507e-124	405.0	COG4102@1|root,COG4102@2|Bacteria,46UQM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6815558_5	329726.AM1_3687	1.072e-10	67.0	2EJ72@1|root,33CY7@2|Bacteria,1GB8K@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6815558_6	935866.JAER01000053_gene2968	6.324e-06	55.0	2EJ72@1|root,33CY7@2|Bacteria,2GXXX@201174|Actinobacteria,4DVHD@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6815558_3	497964.CfE428DRAFT_5059	2.794e-68	239.0	COG4675@1|root,COG4675@2|Bacteria,46T2Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Tail Collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
GDHHQS2_k127_6815558_2	1040983.AXAE01000038_gene2561	2.456e-72	248.0	COG4675@1|root,COG4675@2|Bacteria,1RINS@1224|Proteobacteria,2VFFG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
GDHHQS2_k127_6815558_1	266835.14024494	1.798e-73	252.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2U8Y9@28211|Alphaproteobacteria,43PNV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
GDHHQS2_k127_6815558_4	118173.KB235914_gene764	2.697e-45	169.0	COG0454@1|root,COG0456@2|Bacteria,1G6J0@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6820613_2	234267.Acid_6577	1.738e-82	310.0	COG1470@1|root,COG3210@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,He_PIG,PATR,SLH
GDHHQS2_k127_6820613_0	639030.JHVA01000001_gene2494	1.573e-132	436.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria,2JIM6@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
GDHHQS2_k127_6820613_1	234267.Acid_3566	7.391e-83	286.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
GDHHQS2_k127_6820613_3	502025.Hoch_3142	9.957e-33	130.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,431FU@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
GDHHQS2_k127_6820613_5	1122214.AQWH01000007_gene1860	5.304e-10	61.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,2PM7E@255475|Aurantimonadaceae	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GDHHQS2_k127_6826647_8	1123508.JH636441_gene3779	8.869e-66	233.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Hepar_II_III
GDHHQS2_k127_6826647_0	234267.Acid_5273	3.767e-269	833.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria	57723|Acidobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS2_k127_6826647_6	234267.Acid_5272	1.712e-108	363.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,3Y7FH@57723|Acidobacteria	57723|Acidobacteria	K	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
GDHHQS2_k127_6826647_9	234267.Acid_0823	3.39e-29	119.0	COG1278@1|root,COG1278@2|Bacteria,3Y8IF@57723|Acidobacteria	57723|Acidobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_6826647_7	234267.Acid_4909	3.401e-102	345.0	COG1082@1|root,COG1082@2|Bacteria,3Y72F@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6826647_5	234267.Acid_4908	3.016e-116	383.0	COG0673@1|root,COG0673@2|Bacteria,3Y6XR@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6826647_4	234267.Acid_4804	3.718e-125	417.0	COG2008@1|root,COG2008@2|Bacteria,3Y7Q8@57723|Acidobacteria	57723|Acidobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS2_k127_6826647_1	234267.Acid_7663	6.668e-169	532.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_6826647_3	682795.AciX8_2687	3.528e-145	473.0	COG0493@1|root,COG0493@2|Bacteria,3Y3EA@57723|Acidobacteria,2JJCC@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R10159,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS2_k127_6826647_2	234267.Acid_7660	4.875e-156	495.0	COG0167@1|root,COG1149@1|root,COG0167@2|Bacteria,COG1149@2|Bacteria,3Y3D8@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM Dihydroorotate dehydrogenase	-	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
GDHHQS2_k127_6839753_2	1267535.KB906767_gene2721	3.595e-139	447.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_6839753_5	234267.Acid_3185	8.795e-103	342.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	afr	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6839753_8	234267.Acid_0534	5.074e-78	275.0	COG3480@1|root,COG3509@1|root,COG3480@2|Bacteria,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	lon	-	-	ko:K03932,ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	CE1	-	Esterase_phd,Lon_C,PDZ_2
GDHHQS2_k127_6839753_10	1267535.KB906767_gene5190	1.114e-71	254.0	COG0457@1|root,COG0457@2|Bacteria,3Y4RD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
GDHHQS2_k127_6839753_6	1340493.JNIF01000003_gene4564	9.082e-90	311.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181	ko:K00568,ko:K18827	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781,R10657,R10658	RC00002,RC00003,RC00078,RC00392,RC01895,RC03220	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_6839753_4	886293.Sinac_5999	8.767e-107	362.0	COG5476@1|root,COG5476@2|Bacteria,2IY2W@203682|Planctomycetes	203682|Planctomycetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
GDHHQS2_k127_6839753_1	1396418.BATQ01000078_gene592	2.622e-156	499.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
GDHHQS2_k127_6839753_13	234267.Acid_2865	5.343e-49	184.0	COG1028@1|root,COG1028@2|Bacteria,3Y801@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_6839753_0	1267535.KB906767_gene3474	1.462e-182	575.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_6839753_11	357808.RoseRS_2514	7.247e-71	247.0	COG4821@1|root,COG4821@2|Bacteria,2G6XP@200795|Chloroflexi	200795|Chloroflexi	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
GDHHQS2_k127_6839753_7	234267.Acid_2864	1.547e-81	281.0	COG1940@1|root,COG1940@2|Bacteria,3Y7MC@57723|Acidobacteria	57723|Acidobacteria	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_6839753_14	1313172.YM304_01250	1.737e-07	61.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_6839753_9	1078020.KEK_09157	7.314e-72	256.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,2362Z@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_6839753_3	1380390.JIAT01000001_gene5084	8.034e-120	397.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_6839753_12	1267535.KB906767_gene2875	7.887e-54	199.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_6839753_15	1382356.JQMP01000004_gene559	6.06e-06	50.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi,27YII@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS2_k127_6842146_2	234267.Acid_2609	6.387e-37	142.0	2A5Y1@1|root,30UQ2@2|Bacteria,3Y7MH@57723|Acidobacteria	57723|Acidobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GDHHQS2_k127_6842146_0	1340493.JNIF01000003_gene2930	2.665e-120	398.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS2_k127_6842146_3	518766.Rmar_2158	7.152e-19	94.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6842146_1	1174684.EBMC1_16159	1.223e-56	205.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2TTI5@28211|Alphaproteobacteria,2K1R1@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6845947_1	1396418.BATQ01000151_gene2365	1.449e-25	108.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
GDHHQS2_k127_6845947_0	1403819.BATR01000083_gene2428	1.197e-98	328.0	COG0580@1|root,COG0580@2|Bacteria,46UTI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Major intrinsic protein	-	-	-	-	-	-	-	-	-	-	-	-	MIP
GDHHQS2_k127_6845947_2	1183438.GKIL_0141	9.388e-17	91.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CAP,HemolysinCabind,LGFP,VanY
GDHHQS2_k127_6858990_1	1340493.JNIF01000003_gene1952	2.908e-70	241.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
GDHHQS2_k127_6858990_0	1340493.JNIF01000003_gene1952	3.209e-138	456.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
GDHHQS2_k127_6858990_2	231434.JQJH01000013_gene2937	4.543e-27	114.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2U1NF@28211|Alphaproteobacteria,3NBIR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
GDHHQS2_k127_6859186_0	1340493.JNIF01000003_gene1507	0.0	1132.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS2_k127_6862613_2	1340493.JNIF01000004_gene757	5.246e-81	289.0	COG5002@1|root,COG5002@2|Bacteria,3Y9FP@57723|Acidobacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,MASE1,MHYT,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,SBP_bac_3
GDHHQS2_k127_6862613_0	1340493.JNIF01000003_gene4211	1.432e-144	472.0	COG0513@1|root,COG0513@2|Bacteria,3Y2M6@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS2_k127_6862613_3	234267.Acid_7083	1.076e-78	267.0	COG1778@1|root,COG1778@2|Bacteria,3Y5BY@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
GDHHQS2_k127_6862613_1	234267.Acid_7417	1.313e-106	374.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	DUF3367,PMT_2
GDHHQS2_k127_6862613_4	234267.Acid_3965	5.97e-27	118.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,CUB,Calx-beta,DUF3739,Haemagg_act,SdrD_B
GDHHQS2_k127_6865272_0	1340493.JNIF01000003_gene4600	6.354e-237	773.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6865272_1	279238.Saro_1583	7.46e-52	197.0	COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6865272_2	234267.Acid_3357	8.083e-26	112.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6865703_0	909663.KI867150_gene2397	7.477e-40	167.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2MQF2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg
GDHHQS2_k127_686717_0	1267535.KB906767_gene1536	3.008e-179	594.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6873948_1	379066.GAU_2306	2.172e-148	483.0	COG0534@1|root,COG0534@2|Bacteria,1ZT3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS2_k127_6873948_4	1340493.JNIF01000003_gene2630	1.785e-70	246.0	COG1482@1|root,COG1482@2|Bacteria,3Y44Q@57723|Acidobacteria	57723|Acidobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
GDHHQS2_k127_6873948_0	234267.Acid_7274	3.074e-189	597.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_6873948_6	234267.Acid_7275	1.042e-62	223.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria	57723|Acidobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS2_k127_6873948_3	1340493.JNIF01000003_gene2627	5.29e-93	316.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6873948_2	234267.Acid_6104	3.184e-113	373.0	COG4632@1|root,COG4632@2|Bacteria,3Y8TM@57723|Acidobacteria	57723|Acidobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GDHHQS2_k127_6873948_10	1206735.BAGG01000046_gene1993	2.794e-10	70.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4FXIS@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_6873948_9	204669.Acid345_0782	1.052e-22	101.0	2CDT8@1|root,33C3R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6873948_5	196490.AUEZ01000036_gene6081	9.153e-66	242.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
GDHHQS2_k127_6873948_8	234267.Acid_3517	2.588e-35	145.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
GDHHQS2_k127_6873948_7	234267.Acid_2380	3.555e-52	193.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
GDHHQS2_k127_6874432_2	1267533.KB906740_gene287	1.398e-19	94.0	COG0457@1|root,COG0823@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	DUF4214,SBBP,TPR_19
GDHHQS2_k127_6874432_0	234267.Acid_4601	1.209e-150	483.0	COG0524@1|root,COG0524@2|Bacteria,3Y3GE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS2_k127_6874432_1	234267.Acid_4600	1.84e-140	463.0	COG1807@1|root,COG1807@2|Bacteria,3Y3BJ@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_687665_0	1340493.JNIF01000003_gene1814	2.556e-81	293.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_68790_1	1340493.JNIF01000003_gene2736	1.421e-146	479.0	COG2755@1|root,COG2755@2|Bacteria,3Y7PE@57723|Acidobacteria	57723|Acidobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_68790_0	1340493.JNIF01000003_gene2737	9.911e-168	539.0	COG1696@1|root,COG1696@2|Bacteria,3Y4ZP@57723|Acidobacteria	57723|Acidobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
GDHHQS2_k127_68790_2	1379270.AUXF01000001_gene2450	1.268e-42	157.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6881742_7	234267.Acid_7127	2.219e-29	117.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria	57723|Acidobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GDHHQS2_k127_6881742_5	1120950.KB892720_gene1876	1.735e-43	161.0	COG3254@1|root,COG3254@2|Bacteria,2IQ69@201174|Actinobacteria,4DRUW@85009|Propionibacteriales	201174|Actinobacteria	S	L-rhamnose mutarotase	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
GDHHQS2_k127_6881742_6	1123073.KB899245_gene23	5.679e-43	178.0	COG3291@1|root,COG4102@1|root,COG3291@2|Bacteria,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cleaved_Adhesin,Reprolysin_4
GDHHQS2_k127_6881742_8	497964.CfE428DRAFT_5423	4.269e-29	122.0	2EPF9@1|root,33H1X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6881742_3	1123508.JH636452_gene7045	1.371e-93	324.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6881742_9	204669.Acid345_2059	4.867e-17	83.0	COG1923@1|root,COG1923@2|Bacteria,3Y5PK@57723|Acidobacteria,2JJYT@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
GDHHQS2_k127_6881742_2	234267.Acid_5909	7.039e-125	407.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_6881742_10	1121926.AXWO01000018_gene2546	4.596e-08	63.0	COG0500@1|root,COG2226@2|Bacteria,2HF1V@201174|Actinobacteria,4F0BC@85014|Glycomycetales	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_6881742_1	1408473.JHXO01000005_gene1746	1.61e-134	442.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_6881742_4	697282.Mettu_2234	1.44e-71	261.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_6881742_0	1340493.JNIF01000004_gene88	3.137e-150	499.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6883381_0	497964.CfE428DRAFT_4464	7.363e-131	428.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_6887270_4	467661.RKLH11_646	7.547e-05	49.0	2DX1G@1|root,342Z1@2|Bacteria,1NYIP@1224|Proteobacteria,2USYV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6887270_0	748280.NH8B_1819	2.549e-77	267.0	COG1018@1|root,COG1018@2|Bacteria,1RAS4@1224|Proteobacteria,2VQ3I@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
GDHHQS2_k127_6887270_1	638303.Thal_0236	1.237e-15	81.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	zf-CDGSH
GDHHQS2_k127_6887270_2	472759.Nhal_3413	8.244e-13	69.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X250@135613|Chromatiales	135613|Chromatiales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_688825_0	1209072.ALBT01000044_gene2518	1.25e-65	227.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,1S7AB@1236|Gammaproteobacteria,1FI97@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_688825_1	1095769.CAHF01000005_gene1539	3.366e-27	121.0	COG0671@1|root,COG0671@2|Bacteria,1N80J@1224|Proteobacteria,2WB8Z@28216|Betaproteobacteria,4759Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Protein of unknown function (DUF3703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3703
GDHHQS2_k127_688825_2	1333856.L686_18705	5.956e-27	115.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S5JT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
GDHHQS2_k127_6891090_11	1122921.KB898185_gene3648	4.675e-30	124.0	COG2764@1|root,COG2764@2|Bacteria,1V3WE@1239|Firmicutes,4HJQB@91061|Bacilli,275UJ@186822|Paenibacillaceae	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
GDHHQS2_k127_6891090_9	234267.Acid_3108	3.129e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,3Y5V6@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6891090_0	518766.Rmar_0690	6.739e-152	494.0	COG1457@1|root,COG1457@2|Bacteria,4NHHC@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6891090_4	1340493.JNIF01000003_gene1790	8.479e-85	291.0	COG1162@1|root,COG1162@2|Bacteria	2|Bacteria	S	GTPase activity	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
GDHHQS2_k127_6891090_2	927677.ALVU02000001_gene4596	1.105e-104	368.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1GAED@1117|Cyanobacteria	1117|Cyanobacteria	C	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS2_k127_6891090_8	234267.Acid_4829	1.043e-58	210.0	COG1057@1|root,COG1057@2|Bacteria,3Y5D2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS2_k127_6891090_1	1340493.JNIF01000004_gene948	3.531e-106	351.0	COG0157@1|root,COG0157@2|Bacteria,3Y2H5@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GDHHQS2_k127_6891090_6	1267535.KB906767_gene4716	7.031e-66	235.0	COG0340@1|root,COG0340@2|Bacteria,3Y4PB@57723|Acidobacteria,2JJAU@204432|Acidobacteriia	204432|Acidobacteriia	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
GDHHQS2_k127_6891090_3	234267.Acid_7558	2.891e-104	346.0	COG1521@1|root,COG1521@2|Bacteria,3Y398@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS2_k127_6891090_5	234267.Acid_7557	3.886e-74	256.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6891090_10	234267.Acid_6760	1.124e-44	172.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS2_k127_6891090_7	886293.Sinac_2845	1.509e-63	228.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
GDHHQS2_k127_6892018_0	234267.Acid_6265	5.992e-118	404.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_6892018_1	234267.Acid_5940	2.36e-40	152.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6894611_0	1340493.JNIF01000003_gene3433	2.261e-209	666.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_6901594_3	1267535.KB906767_gene3692	1.007e-08	66.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
GDHHQS2_k127_6901594_0	1267535.KB906767_gene3693	2.152e-178	572.0	COG0248@1|root,COG0248@2|Bacteria,3Y3H5@57723|Acidobacteria,2JIDG@204432|Acidobacteriia	204432|Acidobacteriia	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
GDHHQS2_k127_6901594_1	1340493.JNIF01000003_gene1469	5.546e-119	400.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria	57723|Acidobacteria	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
GDHHQS2_k127_6901594_2	1340493.JNIF01000003_gene1468	8.444e-24	102.0	COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria	57723|Acidobacteria	S	nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
GDHHQS2_k127_6905356_3	231434.JQJH01000013_gene2952	1.058e-10	63.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2U2PF@28211|Alphaproteobacteria,3NCFI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
GDHHQS2_k127_6905356_1	768671.ThimaDRAFT_1778	5.594e-73	257.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
GDHHQS2_k127_6905356_2	383372.Rcas_2746	3.772e-40	155.0	COG0622@1|root,COG0622@2|Bacteria,2G7DJ@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
GDHHQS2_k127_6905356_0	1340493.JNIF01000003_gene3500	1.634e-199	626.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	dgoD	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_6909895_7	234267.Acid_7396	3.735e-16	81.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808,ko:K05809	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
GDHHQS2_k127_6909895_1	234267.Acid_7395	1.611e-119	390.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria	57723|Acidobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
GDHHQS2_k127_6909895_2	929703.KE386491_gene3265	1.557e-38	155.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,47Y1I@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS2_k127_6909895_3	1197906.CAJQ02000021_gene4544	5.93e-33	134.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,3K009@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,Cupin_7,DUF4437
GDHHQS2_k127_6909895_6	406124.ACPC01000007_gene3387	9.711e-22	100.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	MA20_35785	-	2.5.1.18	ko:K00799,ko:K04750	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1
GDHHQS2_k127_6909895_5	1123073.KB899242_gene1024	8.615e-26	111.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,1S9NT@1236|Gammaproteobacteria,1X7N9@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_6909895_4	234267.Acid_7805	5.046e-32	128.0	COG2346@1|root,COG2346@2|Bacteria,3Y8WS@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS2_k127_6909895_0	1340493.JNIF01000004_gene789	2.318e-149	486.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepPQ	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_691427_1	234267.Acid_3957	7.606e-66	233.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
GDHHQS2_k127_691427_2	234267.Acid_1247	0.0002708	49.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	pph2	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_691427_0	682795.AciX8_4746	8.597e-89	329.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria,2JICG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6915836_0	1340493.JNIF01000003_gene1756	8.678e-168	546.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
GDHHQS2_k127_6915836_1	1340493.JNIF01000003_gene1755	3.683e-80	271.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6919506_1	1458462.JNLK01000001_gene773	1.802e-45	186.0	COG3391@1|root,COG5263@1|root,COG3391@2|Bacteria,COG5263@2|Bacteria,1UV67@1239|Firmicutes,24AV9@186801|Clostridia,27TEP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Cadherin-like
GDHHQS2_k127_6919506_0	344747.PM8797T_06205	8.668e-265	827.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_6922717_3	1267535.KB906767_gene3910	2.341e-08	59.0	COG2063@1|root,COG2063@2|Bacteria,3Y3D6@57723|Acidobacteria,2JIIJ@204432|Acidobacteriia	204432|Acidobacteriia	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
GDHHQS2_k127_6922717_2	234267.Acid_7452	6.64e-39	158.0	COG1261@1|root,COG1261@2|Bacteria,3Y8G9@57723|Acidobacteria	57723|Acidobacteria	NO	Chaperone for flagella basal body P-ring formation	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
GDHHQS2_k127_6922717_0	234267.Acid_7453	4.939e-128	414.0	COG4786@1|root,COG4786@2|Bacteria,3Y3K1@57723|Acidobacteria	57723|Acidobacteria	N	flagellar basal-body rod protein FlgG	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS2_k127_6922717_1	234267.Acid_7454	8.876e-69	242.0	COG4786@1|root,COG4786@2|Bacteria,3Y2HI@57723|Acidobacteria	57723|Acidobacteria	N	basal body rod protein	-	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
GDHHQS2_k127_6924649_11	96561.Dole_2594	1.043e-17	85.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WJS7@28221|Deltaproteobacteria,2MIWA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6924649_10	338966.Ppro_0061	1.602e-24	108.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,43T12@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_6924649_1	1267535.KB906767_gene4813	9.226e-201	636.0	COG0554@1|root,COG0554@2|Bacteria,3Y37H@57723|Acidobacteria,2JHWC@204432|Acidobacteriia	204432|Acidobacteriia	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_6924649_8	234267.Acid_1752	2.786e-42	160.0	2CBQR@1|root,32RTV@2|Bacteria,3Y57Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6924649_2	595460.RRSWK_06791	1.725e-183	593.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Sulfatase
GDHHQS2_k127_6924649_12	401053.AciPR4_3351	6.976e-05	50.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_6924649_7	1340493.JNIF01000003_gene3303	1.439e-79	273.0	COG1018@1|root,COG1018@2|Bacteria,3Y4SB@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS2_k127_6924649_9	234267.Acid_7485	6.229e-31	126.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
GDHHQS2_k127_6924649_3	944480.ATUV01000001_gene504	1.687e-167	546.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2M6EX@213113|Desulfurellales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_6924649_5	1340493.JNIF01000003_gene1463	9.944e-122	402.0	2CH0S@1|root,341IR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6924649_6	717605.Theco_3215	1.452e-90	310.0	COG0667@1|root,COG0667@2|Bacteria,1TRIU@1239|Firmicutes,4HCJC@91061|Bacilli,26QUS@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_6924649_4	234267.Acid_7692	2.15e-159	511.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria	57723|Acidobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS2_k127_6924649_0	234267.Acid_7693	7.835e-297	922.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
GDHHQS2_k127_6928015_1	1340493.JNIF01000003_gene4590	4.014e-67	239.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_6928015_2	748247.AZKH_1286	1.22e-06	57.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria,2KUB7@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS2_k127_6928015_0	886293.Sinac_3870	8.832e-154	499.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6931821_0	240016.ABIZ01000001_gene2585	3.502e-149	490.0	COG0477@1|root,COG0477@2|Bacteria,46TEM@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
GDHHQS2_k127_6931821_1	1298880.AUEV01000002_gene1751	2.018e-50	180.0	COG1914@1|root,COG1914@2|Bacteria,2GMUT@201174|Actinobacteria	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6934522_0	682795.AciX8_0334	6.608e-169	582.0	COG0457@1|root,COG0457@2|Bacteria	682795.AciX8_0334|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6934522_2	265072.Mfla_2494	3.838e-06	54.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,2KM2T@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS2_k127_6935015_6	234267.Acid_2180	2.28e-49	185.0	COG0500@1|root,COG2226@2|Bacteria,3Y7D3@57723|Acidobacteria	57723|Acidobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_6935015_10	234267.Acid_1723	2.627e-21	95.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS2_k127_6935015_1	234267.Acid_1533	0.0	1054.0	COG2866@1|root,COG2866@2|Bacteria,3Y416@57723|Acidobacteria	57723|Acidobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_6935015_2	234267.Acid_6472	7.143e-253	789.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria	57723|Acidobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS2_k127_6935015_4	1121381.JNIV01000146_gene4057	5.057e-91	317.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1WJ0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS2_k127_6935015_9	1234364.AMSF01000015_gene3208	8.669e-29	121.0	COG1765@1|root,COG1765@2|Bacteria,1N1RR@1224|Proteobacteria,1S3KI@1236|Gammaproteobacteria,1X77I@135614|Xanthomonadales	135614|Xanthomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS2_k127_6935015_3	234267.Acid_4739	4.067e-190	599.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS2_k127_6935015_5	1340493.JNIF01000003_gene2135	6.95e-85	288.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_6935015_0	234267.Acid_3358	0.0	1359.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6935015_11	330214.NIDE2342	9.661e-14	76.0	COG1516@1|root,COG1516@2|Bacteria,3J1A2@40117|Nitrospirae	40117|Nitrospirae	N	Flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
GDHHQS2_k127_6935015_12	123214.PERMA_1619	2.697e-06	53.0	COG1334@1|root,COG1334@2|Bacteria,2G4BI@200783|Aquificae	200783|Aquificae	N	flagellar protein FlaG	-	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
GDHHQS2_k127_6935015_7	1267535.KB906767_gene5038	1.535e-39	166.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_6935015_8	76114.c1A220	4.612e-37	157.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_6935253_0	1123278.KB893565_gene3538	9.796e-185	603.0	COG2866@1|root,COG2866@2|Bacteria,4NF3D@976|Bacteroidetes,47UEQ@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_6935253_3	502025.Hoch_4783	2.053e-25	117.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria,2Z1AY@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_6935253_1	234267.Acid_4697	2.027e-114	383.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS2_k127_6935253_2	1340493.JNIF01000003_gene4811	5.673e-67	234.0	COG0760@1|root,COG0760@2|Bacteria,3Y42Z@57723|Acidobacteria	57723|Acidobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
GDHHQS2_k127_6936456_2	502025.Hoch_2503	1.486e-38	152.0	29R44@1|root,2ZYCT@2|Bacteria,1PV4Q@1224|Proteobacteria,43551@68525|delta/epsilon subdivisions,2WZG1@28221|Deltaproteobacteria,2Z22D@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6936456_1	1267535.KB906767_gene4948	1.509e-72	255.0	COG0329@1|root,COG0329@2|Bacteria,3Y7V6@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_6936456_0	1267535.KB906767_gene4947	1.101e-93	315.0	COG0076@1|root,COG0076@2|Bacteria,3Y2SW@57723|Acidobacteria,2JMFG@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS2_k127_6940942_0	909663.KI867150_gene786	2.826e-143	477.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_6940942_1	595537.Varpa_4165	1.102e-50	189.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria,4AC0W@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_6940942_2	323261.Noc_0167	6.455e-37	139.0	COG1476@1|root,COG1476@2|Bacteria,1QWRE@1224|Proteobacteria,1T2XD@1236|Gammaproteobacteria,1X0ZS@135613|Chromatiales	135613|Chromatiales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS2_k127_6945608_2	666686.B1NLA3E_13575	1.574e-28	122.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4HCAN@91061|Bacilli,1ZDW9@1386|Bacillus	91061|Bacilli	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
GDHHQS2_k127_6945608_0	1095769.CAHF01000023_gene511	7.078e-58	205.0	COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,2VKTG@28216|Betaproteobacteria,477GC@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GDHHQS2_k127_6945608_1	265072.Mfla_1454	5.819e-36	138.0	2E86T@1|root,332K1@2|Bacteria,1N2IR@1224|Proteobacteria,2W3G0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6949057_3	314230.DSM3645_13770	9.417e-82	283.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6949057_0	240016.ABIZ01000001_gene1451	4.96e-159	514.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_6949057_1	314230.DSM3645_16435	2.744e-144	467.0	COG1541@1|root,COG1541@2|Bacteria,2IWUR@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6949057_2	1123242.JH636434_gene5302	2.203e-102	350.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6949057_5	1340493.JNIF01000003_gene1845	7.164e-30	120.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
GDHHQS2_k127_6952250_2	401053.AciPR4_2768	4.196e-06	52.0	COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6952250_0	1340493.JNIF01000004_gene88	4.28e-308	980.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6952250_1	1347342.BN863_18240	7.309e-75	272.0	COG2730@1|root,COG2730@2|Bacteria,4PKHG@976|Bacteroidetes,1I0J9@117743|Flavobacteriia	976|Bacteroidetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
GDHHQS2_k127_6953404_0	309807.SRU_0297	1.765e-77	284.0	COG0793@1|root,COG4219@1|root,COG0793@2|Bacteria,COG4219@2|Bacteria,4NEK8@976|Bacteroidetes	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_6953404_1	1340493.JNIF01000004_gene292	3.003e-45	175.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6953669_1	1340493.JNIF01000003_gene3739	1.732e-115	376.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_6953669_0	234267.Acid_4148	1.825e-299	929.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS2_k127_6953669_2	1353529.M899_1409	4.846e-86	295.0	COG2227@1|root,COG2227@2|Bacteria,1PEUM@1224|Proteobacteria,42VXF@68525|delta/epsilon subdivisions,2MUGQ@213481|Bdellovibrionales,2X20Q@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Methionine biosynthesis protein MetW	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS2_k127_6953669_5	1353529.M899_1410	1.495e-26	125.0	COG0637@1|root,COG0637@2|Bacteria,1RC0Z@1224|Proteobacteria,42Q7Y@68525|delta/epsilon subdivisions,2X5M6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_6953669_3	1340493.JNIF01000002_gene1250	5.122e-60	228.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS2_k127_6953669_4	1340493.JNIF01000002_gene1251	5.829e-31	124.0	COG0391@1|root,COG1215@1|root,COG0391@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K11740,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glycos_transf_2,UPF0052
GDHHQS2_k127_6957392_3	1267535.KB906767_gene457	4.885e-26	109.0	COG0457@1|root,COG0457@2|Bacteria,3Y7U6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6957392_0	234267.Acid_3255	4.351e-153	494.0	COG0282@1|root,COG0282@2|Bacteria,3Y6AP@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	-	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
GDHHQS2_k127_6957392_4	1089550.ATTH01000001_gene731	2.662e-19	98.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_6957392_2	234267.Acid_0471	5.166e-30	130.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
GDHHQS2_k127_6957492_1	234267.Acid_2720	4.017e-173	557.0	COG0624@1|root,COG0624@2|Bacteria,3Y2UM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_6957492_0	234267.Acid_0959	3.392e-205	655.0	COG0514@1|root,COG0514@2|Bacteria,3Y2KM@57723|Acidobacteria	57723|Acidobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RecQ_Zn_bind
GDHHQS2_k127_6957492_2	234267.Acid_0159	1.133e-100	331.0	COG1707@1|root,COG1707@2|Bacteria,3Y6KK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_6970624_3	1144275.COCOR_01560	2.801e-20	94.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_6970624_2	1340493.JNIF01000003_gene4764	5.952e-139	462.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6970624_0	1340493.JNIF01000004_gene277	1.068e-265	829.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6970624_1	1340493.JNIF01000004_gene278	1.182e-141	453.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PD40,PSCyt1,PSCyt2,PSD1,WD40
GDHHQS2_k127_6971392_1	1340493.JNIF01000003_gene1755	3.298e-82	290.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6971392_2	604331.AUHY01000033_gene2397	8.189e-11	76.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria,1WKKN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,SBBP
GDHHQS2_k127_6971392_0	234267.Acid_0738	2.917e-89	303.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
GDHHQS2_k127_6985063_0	234267.Acid_6834	6.409e-81	281.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6985063_1	234267.Acid_1154	5.376e-43	177.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_6986267_0	234267.Acid_0463	6.626e-238	741.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS2_k127_6986267_6	234267.Acid_0462	1.574e-40	156.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GDHHQS2_k127_6986267_7	234267.Acid_0461	5.941e-26	115.0	COG0711@1|root,COG0711@2|Bacteria,3Y4UJ@57723|Acidobacteria	57723|Acidobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS2_k127_6986267_8	234267.Acid_0460	5.746e-25	110.0	COG0711@1|root,COG0711@2|Bacteria,3Y4WK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the ATPase B chain family	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS2_k127_6986267_14	316055.RPE_1402	0.0009065	44.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,2U6PP@28211|Alphaproteobacteria,3K0DW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS2_k127_6986267_13	743836.AYNA01000147_gene537	1.848e-07	56.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,2U6PP@28211|Alphaproteobacteria,370FU@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS2_k127_6986267_12	316055.RPE_1403	8.984e-08	57.0	COG4453@1|root,COG4453@2|Bacteria,1N71W@1224|Proteobacteria,2UI0F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
GDHHQS2_k127_6986267_10	491952.Mar181_2179	6.038e-17	91.0	COG1082@1|root,COG1082@2|Bacteria,1MUQ0@1224|Proteobacteria,1RRXZ@1236|Gammaproteobacteria,1XHB2@135619|Oceanospirillales	135619|Oceanospirillales	G	Xylose isomerase	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_6986267_2	234267.Acid_5876	3.708e-146	473.0	COG0667@1|root,COG0667@2|Bacteria,3Y3KW@57723|Acidobacteria	57723|Acidobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_6986267_5	234267.Acid_7737	1.805e-41	164.0	COG0662@1|root,COG0662@2|Bacteria,3Y7HE@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_6986267_1	234267.Acid_4726	2.817e-185	590.0	COG0308@1|root,COG0308@2|Bacteria,3Y3ZS@57723|Acidobacteria	57723|Acidobacteria	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
GDHHQS2_k127_6986267_3	234267.Acid_6502	5.341e-103	340.0	COG0149@1|root,COG0149@2|Bacteria,3Y2YS@57723|Acidobacteria	57723|Acidobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS2_k127_6986267_11	999419.HMPREF1077_00547	6.652e-13	74.0	2DS8J@1|root,33F07@2|Bacteria,4P102@976|Bacteroidetes,2FW7R@200643|Bacteroidia,22ZDI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6988209_1	234267.Acid_0720	1.142e-111	370.0	COG2333@1|root,COG2333@2|Bacteria,3Y323@57723|Acidobacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_6988209_0	1340493.JNIF01000003_gene3616	2.769e-191	606.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene3616|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_699377_0	1267535.KB906767_gene3187	2.241e-120	399.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CarbopepD_reg_2,Plug
GDHHQS2_k127_699377_1	1047013.AQSP01000070_gene43	2.083e-24	105.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_699377_2	63737.Npun_R4600	7.101e-22	95.0	COG1724@1|root,COG1724@2|Bacteria,1GEWB@1117|Cyanobacteria,1HSYA@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_6995894_1	1040989.AWZU01000056_gene3841	6.162e-46	170.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,2V74D@28211|Alphaproteobacteria,3K3QZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_6995894_0	533247.CRD_00150	1.735e-117	400.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1HK6A@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_6997703_6	1340493.JNIF01000004_gene374	3.428e-19	91.0	297M3@1|root,2ZUU3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6997703_5	1340493.JNIF01000004_gene374	3.124e-33	134.0	297M3@1|root,2ZUU3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6997703_0	1267535.KB906767_gene5043	1.674e-158	511.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
GDHHQS2_k127_6997703_3	234267.Acid_2708	1.046e-78	273.0	COG4221@1|root,COG4221@2|Bacteria,3Y4DX@57723|Acidobacteria	57723|Acidobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_6997703_2	1267535.KB906767_gene5046	1.302e-85	291.0	COG4137@1|root,COG4137@2|Bacteria,3Y9FX@57723|Acidobacteria,2JP17@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS2_k127_6997703_1	1267535.KB906767_gene5047	7.888e-150	488.0	COG0373@1|root,COG0373@2|Bacteria,3Y3DQ@57723|Acidobacteria,2JHR3@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS2_k127_6997703_4	234267.Acid_3179	2.244e-42	160.0	COG0181@1|root,COG0181@2|Bacteria,3Y3RY@57723|Acidobacteria	57723|Acidobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS2_k127_7007072_3	234267.Acid_7724	1.059e-60	222.0	COG0127@1|root,COG0127@2|Bacteria,3Y7Z7@57723|Acidobacteria	57723|Acidobacteria	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS2_k127_7007072_0	1267535.KB906767_gene1411	5.124e-133	440.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
GDHHQS2_k127_7007072_1	234267.Acid_7723	3.212e-99	336.0	COG0689@1|root,COG0689@2|Bacteria,3Y2FP@57723|Acidobacteria	57723|Acidobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GDHHQS2_k127_7007072_4	1343158.SACS_1559	4.059e-13	83.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2JR0F@204441|Rhodospirillales	204441|Rhodospirillales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS2_k127_7007072_2	234267.Acid_0334	7.085e-80	279.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
GDHHQS2_k127_7012435_0	1166018.FAES_5039	4.998e-175	559.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,47NX7@768503|Cytophagia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_702045_8	1267535.KB906767_gene1468	0.0001373	48.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_702045_1	204669.Acid345_0663	1.808e-166	561.0	COG1629@1|root,COG1629@2|Bacteria,3Y3G2@57723|Acidobacteria,2JKEK@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_702045_5	1382359.JIAL01000001_gene60	1.611e-09	61.0	COG4584@1|root,COG4584@2|Bacteria,3Y7RI@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
GDHHQS2_k127_702045_7	861299.J421_1346	4.196e-06	52.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_702045_0	1267535.KB906767_gene1795	2.594e-224	730.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_702045_3	1123277.KB893174_gene5952	2.183e-115	390.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
GDHHQS2_k127_702045_6	234267.Acid_5471	2.506e-08	61.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_702045_4	234267.Acid_3764	1.11e-12	75.0	2DYGW@1|root,349NG@2|Bacteria,3Y8PG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7025374_2	1449076.JOOE01000004_gene156	1.987e-23	111.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,2K00G@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_7025374_1	1117379.BABA_10586	1.681e-84	301.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus	91061|Bacilli	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_7025374_0	234267.Acid_7510	5.09e-103	345.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7027121_4	1340493.JNIF01000003_gene1706	2.038e-57	208.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
GDHHQS2_k127_7027121_3	234267.Acid_0046	1.01e-73	258.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria	57723|Acidobacteria	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GDHHQS2_k127_7027121_0	234267.Acid_0045	5.174e-292	902.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS2_k127_7027121_1	234267.Acid_0044	2.281e-158	509.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS2_k127_7027121_6	1267535.KB906767_gene3604	4.259e-18	89.0	COG1582@1|root,COG1582@2|Bacteria,3Y5M5@57723|Acidobacteria	57723|Acidobacteria	N	PFAM flagellar FlbD family protein	-	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
GDHHQS2_k127_7027121_2	234267.Acid_0332	6.676e-90	303.0	COG1291@1|root,COG1291@2|Bacteria,3Y2VA@57723|Acidobacteria	57723|Acidobacteria	N	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
GDHHQS2_k127_7027121_7	1109445.AGSX01000070_gene91	4.42e-10	61.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1Z16N@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
GDHHQS2_k127_7027300_17	243090.RB7196	0.0001028	47.0	COG4636@1|root,COG4636@2|Bacteria,2J0RA@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_7027300_14	234267.Acid_3938	1.952e-12	71.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_7027300_11	234267.Acid_1884	4.684e-65	229.0	COG5649@1|root,COG5649@2|Bacteria,3Y4QH@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_7027300_8	344747.PM8797T_29862	3.828e-99	343.0	COG1082@1|root,COG1082@2|Bacteria,2J0ZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_7027300_7	1340493.JNIF01000003_gene2371	1.373e-103	342.0	COG1028@1|root,COG1028@2|Bacteria,3Y6NJ@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_7027300_15	204669.Acid345_4754	1.776e-07	59.0	COG1651@1|root,COG1651@2|Bacteria,3Y4S8@57723|Acidobacteria,2JJCA@204432|Acidobacteriia	204432|Acidobacteriia	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS2_k127_7027300_2	929556.Solca_3240	2.487e-214	686.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_7027300_1	234267.Acid_7444	8.87e-222	703.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria	57723|Acidobacteria	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS2_k127_7027300_12	1267534.KB906757_gene928	9.552e-17	84.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7027300_3	1267535.KB906767_gene3137	1.175e-212	686.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_7027300_4	234267.Acid_5231	2.289e-210	663.0	COG0213@1|root,COG0213@2|Bacteria,3Y44B@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS2_k127_7027300_5	1267535.KB906767_gene3243	1.537e-174	561.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria,2JIKE@204432|Acidobacteriia	204432|Acidobacteriia	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
GDHHQS2_k127_7027300_6	234267.Acid_5233	6.205e-120	393.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MB@57723|Acidobacteria	57723|Acidobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_7027300_9	234267.Acid_2976	1.335e-82	289.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_7027300_13	314230.DSM3645_02348	1.799e-15	82.0	COG1977@1|root,COG1977@2|Bacteria,2J1I1@203682|Planctomycetes	203682|Planctomycetes	H	COG1977 Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_7027300_0	926550.CLDAP_06490	2.565e-300	938.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_7027300_10	926550.CLDAP_06500	5.64e-70	239.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_7033612_1	1340493.JNIF01000003_gene3464	3.144e-152	507.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7033612_0	234267.Acid_5471	1.882e-155	522.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_7036293_0	234267.Acid_6506	7.986e-134	437.0	COG3503@1|root,COG3503@2|Bacteria,3Y73K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS2_k127_7036293_1	1340493.JNIF01000004_gene799	2.742e-51	189.0	COG2834@1|root,COG2834@2|Bacteria,3Y51N@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA,LolA_like
GDHHQS2_k127_7037322_1	533240.CRC_01020	3.398e-21	109.0	COG1404@1|root,COG2931@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3121@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
GDHHQS2_k127_7037322_0	278957.ABEA03000027_gene1659	6.384e-98	334.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
GDHHQS2_k127_7043287_5	234267.Acid_6209	1.65e-55	197.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GDHHQS2_k127_7043287_0	234267.Acid_6208	9.036e-233	730.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_B
GDHHQS2_k127_7043287_2	1000565.METUNv1_03581	2.495e-147	487.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2W9QE@28216|Betaproteobacteria,2KZ9H@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_7043287_4	420662.Mpe_A1451	2.089e-104	353.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Twin-arginine translocation pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
GDHHQS2_k127_7043287_1	234267.Acid_4372	6.041e-194	611.0	COG0448@1|root,COG0448@2|Bacteria,3Y35M@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_7043287_6	234267.Acid_4787	5.605e-24	104.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria	57723|Acidobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS2_k127_7043287_3	234267.Acid_5257	3.16e-143	465.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidase S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_7046947_3	483219.LILAB_20800	9.669e-05	54.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_7046947_0	1047013.AQSP01000121_gene2697	1.944e-257	818.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_7046947_1	1173027.Mic7113_5969	2.073e-68	240.0	COG4104@1|root,COG4104@2|Bacteria,1G6FA@1117|Cyanobacteria,1HFMG@1150|Oscillatoriales	1117|Cyanobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
GDHHQS2_k127_7046947_2	234267.Acid_3432	4.345e-05	54.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
GDHHQS2_k127_7053004_3	1144319.PMI16_03016	1.305e-47	178.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2VKPD@28216|Betaproteobacteria,474PY@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_7053004_0	234267.Acid_3659	2.162e-142	462.0	2DBK2@1|root,2Z9Q1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7053004_2	266835.14023081	1.699e-100	341.0	COG2041@1|root,COG2041@2|Bacteria,1NR5V@1224|Proteobacteria,2UQ6F@28211|Alphaproteobacteria,43R8Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GDHHQS2_k127_7053004_1	234267.Acid_4830	2.191e-116	413.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7058218_0	1267535.KB906767_gene2701	2.389e-146	466.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria,2JI2K@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
GDHHQS2_k127_7058218_3	234267.Acid_5114	7.812e-45	164.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria	57723|Acidobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
GDHHQS2_k127_7058218_2	234267.Acid_5113	5.491e-45	170.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria	57723|Acidobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
GDHHQS2_k127_7058218_1	234267.Acid_5112	3.951e-129	418.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
GDHHQS2_k127_7058218_4	1267535.KB906767_gene2697	5.345e-42	154.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria	57723|Acidobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
GDHHQS2_k127_7058462_1	706587.Desti_0504	2.282e-42	164.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,2MRTF@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS2_k127_7058462_0	1267535.KB906767_gene3083	3.53e-142	467.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7063444_0	234267.Acid_1227	1.01e-57	219.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1227|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7073923_4	1267535.KB906767_gene4164	4.049e-17	83.0	COG1722@1|root,COG1722@2|Bacteria,3Y5RT@57723|Acidobacteria	57723|Acidobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS2_k127_7073923_0	234267.Acid_1114	1.607e-115	380.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_7073923_3	497964.CfE428DRAFT_5378	1.81e-73	254.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS2_k127_7073923_1	1267535.KB906767_gene30	1.409e-111	370.0	COG0061@1|root,COG0061@2|Bacteria,3Y3E6@57723|Acidobacteria,2JIH5@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS2_k127_7073923_2	234267.Acid_1117	9.865e-89	301.0	COG1301@1|root,COG1301@2|Bacteria,3Y2G6@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2	-	-	SDF
GDHHQS2_k127_7074808_0	533240.CRC_01020	6.79e-71	273.0	COG1404@1|root,COG2931@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3121@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
GDHHQS2_k127_7075047_2	243090.RB2098	3.841e-150	496.0	COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,2IY88@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Beta-lactamase
GDHHQS2_k127_7075047_0	1122605.KB893637_gene3269	6.365e-184	608.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_7075047_4	344747.PM8797T_16675	7.194e-88	308.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_7075047_6	234267.Acid_2867	4.576e-39	154.0	2EIAS@1|root,33C26@2|Bacteria,3Y5X7@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7075047_3	1340493.JNIF01000003_gene3721	1.611e-137	449.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria	57723|Acidobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS2_k127_7075047_1	1267535.KB906767_gene2558	2.444e-156	505.0	COG0849@1|root,COG0849@2|Bacteria,3Y432@57723|Acidobacteria,2JI1Q@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS2_k127_7075047_7	234267.Acid_7309	1.379e-09	60.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS2_k127_7081267_0	1340493.JNIF01000004_gene927	2.785e-210	669.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_7088890_0	234267.Acid_1005	7.382e-45	174.0	COG1073@1|root,COG1073@2|Bacteria,3Y5MV@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
GDHHQS2_k127_7090713_2	234267.Acid_0583	1.522e-51	187.0	COG3191@1|root,COG3191@2|Bacteria,3Y6EN@57723|Acidobacteria	57723|Acidobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GDHHQS2_k127_7090713_3	502025.Hoch_2462	1.409e-50	182.0	COG0346@1|root,COG0346@2|Bacteria,1RCGK@1224|Proteobacteria,43375@68525|delta/epsilon subdivisions,2WYIM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_7090713_4	639030.JHVA01000001_gene3437	2.448e-34	137.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
GDHHQS2_k127_7090713_5	1267535.KB906767_gene449	6.172e-09	61.0	2EQAC@1|root,33HWH@2|Bacteria,3Y5W6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7090713_0	886293.Sinac_5994	8.872e-111	388.0	COG3119@1|root,COG3119@2|Bacteria,2IYSH@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_7090713_1	234267.Acid_7405	8.408e-72	253.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS2_k127_7090713_6	28072.Nos7524_4290	0.0003561	48.0	COG4634@1|root,COG4634@2|Bacteria,1G7AE@1117|Cyanobacteria,1HPMX@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092157_1	234267.Acid_0922	1.371e-77	261.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,3Y7VB@57723|Acidobacteria	57723|Acidobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
GDHHQS2_k127_7092157_2	1267535.KB906767_gene1750	7.593e-29	119.0	COG0184@1|root,COG0184@2|Bacteria,3Y5R5@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal_S15	-	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS2_k127_7092157_0	1267535.KB906767_gene1751	1.377e-98	328.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS2_k127_7092496_2	234267.Acid_6001	1.867e-67	245.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,3Y5BB@57723|Acidobacteria	57723|Acidobacteria	N	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
GDHHQS2_k127_7092496_0	929556.Solca_2421	3.319e-257	809.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_7092496_3	1185876.BN8_03041	1.658e-41	156.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,47QED@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
GDHHQS2_k127_7092496_1	234267.Acid_7276	1.395e-206	657.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria	2|Bacteria	EH	PFAM Thiamine pyrophosphate	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_709529_1	1123242.JH636434_gene5302	1.897e-87	305.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_709529_2	555793.WSK_2015	2.13e-20	92.0	COG4974@1|root,COG4974@2|Bacteria,1P6SG@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_709529_0	861299.J421_1876	1.199e-104	346.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_7100417_0	926550.CLDAP_19940	6.134e-198	632.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GDHHQS2_k127_7106391_1	886293.Sinac_7086	9.119e-145	486.0	COG0330@1|root,COG2217@1|root,COG0330@2|Bacteria,COG2217@2|Bacteria,2IWRY@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	Band_7,E1-E2_ATPase,Hydrolase
GDHHQS2_k127_7106391_0	1267535.KB906767_gene4432	2.009e-232	749.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7108145_2	926569.ANT_04490	2.846e-25	106.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
GDHHQS2_k127_7108145_0	926569.ANT_04500	1.11e-171	545.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS2_k127_7108145_1	926569.ANT_04510	1.631e-132	425.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS2_k127_7111204_0	221288.JH992901_gene1091	7.26e-135	437.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,Glyco_hydro_63
GDHHQS2_k127_7111204_1	1396141.BATP01000034_gene4198	2.321e-22	108.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
GDHHQS2_k127_71149_0	1121481.AUAS01000003_gene3781	2.228e-63	228.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_71149_1	344747.PM8797T_19071	1.325e-53	196.0	COG0673@1|root,COG0673@2|Bacteria,2IX5C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_7121534_2	195253.Syn6312_3586	1.084e-40	161.0	COG0226@1|root,COG0226@2|Bacteria,1G0SW@1117|Cyanobacteria,1GYE5@1129|Synechococcus	1117|Cyanobacteria	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS2_k127_7121534_4	316057.RPD_2255	4.597e-27	119.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria,2U0F4@28211|Alphaproteobacteria,3JVIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7121534_1	1123258.AQXZ01000019_gene3630	1.126e-63	232.0	COG1414@1|root,COG1414@2|Bacteria,2I3CC@201174|Actinobacteria,4FWJM@85025|Nocardiaceae	201174|Actinobacteria	K	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS2_k127_7121534_3	234267.Acid_4211	5.251e-30	132.0	2DFMP@1|root,2ZSBB@2|Bacteria,3Y8UP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7121534_0	639030.JHVA01000001_gene590	9.909e-120	411.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7123549_1	234267.Acid_3917	5.759e-88	295.0	COG2220@1|root,COG2220@2|Bacteria,3Y4RK@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS2_k127_7123549_0	1340493.JNIF01000002_gene1241	1.058e-171	579.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	2|Bacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
GDHHQS2_k127_7123549_2	1340493.JNIF01000003_gene2143	8.795e-66	240.0	COG0438@1|root,COG0438@2|Bacteria,3Y8IN@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_7123549_3	1121378.KB899745_gene3737	3.871e-24	108.0	COG0582@1|root,COG0582@2|Bacteria,1WM1D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
GDHHQS2_k127_7124231_2	1267535.KB906767_gene4252	5.408e-158	505.0	COG3119@1|root,COG3119@2|Bacteria,3Y7FV@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF229)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_7124231_1	1340493.JNIF01000003_gene3611	2.572e-184	582.0	COG0505@1|root,COG0505@2|Bacteria,3Y31Y@57723|Acidobacteria	57723|Acidobacteria	EF	TIGRFAM Carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS2_k127_7124231_0	1267535.KB906767_gene717	0.0	1729.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria,2JIJZ@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS2_k127_7124231_3	234267.Acid_7075	1.688e-103	354.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria	57723|Acidobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS2_k127_7124231_4	234267.Acid_5547	5.649e-79	276.0	COG0392@1|root,COG0392@2|Bacteria,3Y7S6@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GDHHQS2_k127_7124231_5	1267535.KB906767_gene3468	6.602e-27	113.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,3Y2RB@57723|Acidobacteria,2JIRW@204432|Acidobacteriia	204432|Acidobacteriia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GDHHQS2_k127_7125453_0	886293.Sinac_0947	5.86e-297	937.0	COG2010@1|root,COG2010@2|Bacteria,2IY86@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_7125453_4	1433126.BN938_1424	5.571e-31	135.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
GDHHQS2_k127_7125453_2	234267.Acid_7833	1.579e-64	233.0	COG1309@1|root,COG1309@2|Bacteria,3Y4QT@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_7125453_5	886293.Sinac_1891	5.145e-29	123.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
GDHHQS2_k127_7125453_3	886293.Sinac_1890	1.507e-39	151.0	2DN6W@1|root,32UIF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7125453_1	383372.Rcas_1067	1.066e-80	274.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
GDHHQS2_k127_7125453_6	1122951.ATUE01000006_gene1187	1.712e-27	113.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,3NN1M@468|Moraxellaceae	1236|Gammaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
GDHHQS2_k127_7130785_0	278963.ATWD01000001_gene2919	2.414e-79	284.0	COG1629@1|root,COG4771@2|Bacteria,3Y778@57723|Acidobacteria,2JKG8@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7131151_3	234267.Acid_3432	1.812e-128	427.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
GDHHQS2_k127_7131151_6	309801.trd_1072	4.527e-39	156.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	hpaG	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,RraA-like
GDHHQS2_k127_7131151_2	234267.Acid_2026	4.561e-225	706.0	COG1219@1|root,COG1219@2|Bacteria,3Y3MR@57723|Acidobacteria	57723|Acidobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GDHHQS2_k127_7131151_0	234267.Acid_2027	0.0	1309.0	COG0466@1|root,COG0466@2|Bacteria,3Y3DI@57723|Acidobacteria	57723|Acidobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_7131151_5	234267.Acid_2028	2.019e-59	213.0	COG0218@1|root,COG0218@2|Bacteria,3Y4H6@57723|Acidobacteria	57723|Acidobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
GDHHQS2_k127_7131151_1	1267535.KB906767_gene3177	1.449e-250	788.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS2_k127_7131151_4	1340493.JNIF01000003_gene2328	4.129e-115	392.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_7134670_1	234267.Acid_7539	9.347e-29	121.0	COG0724@1|root,COG0724@2|Bacteria,3Y59V@57723|Acidobacteria	57723|Acidobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS2_k127_7134670_0	234267.Acid_0979	1.322e-256	807.0	COG0654@1|root,COG0654@2|Bacteria	2|Bacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_7134670_3	240016.ABIZ01000001_gene2858	4.101e-15	89.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GDHHQS2_k127_7134670_2	1206731.BAGB01000063_gene7395	5.598e-23	109.0	COG3618@1|root,COG3618@2|Bacteria,2IE24@201174|Actinobacteria,4G6M7@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_7136247_1	926550.CLDAP_09900	5.598e-26	127.0	COG3391@1|root,COG3391@2|Bacteria,2G9E4@200795|Chloroflexi	200795|Chloroflexi	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7136247_0	1089547.KB913013_gene3595	4.23e-42	181.0	COG3203@1|root,COG3203@2|Bacteria,4PM6S@976|Bacteroidetes,47Y33@768503|Cytophagia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GDHHQS2_k127_7146908_1	1123242.JH636434_gene5306	2.486e-82	277.0	COG4102@1|root,COG4102@2|Bacteria,2IY8C@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_7146908_2	1173020.Cha6605_2589	9.3e-16	84.0	COG3668@1|root,COG3668@2|Bacteria,1G90A@1117|Cyanobacteria	1117|Cyanobacteria	S	Plasmid stabilization system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_7146908_3	163908.KB235896_gene1557	1.559e-06	53.0	COG3609@1|root,COG3609@2|Bacteria,1G98M@1117|Cyanobacteria,1HPZQ@1161|Nostocales	1117|Cyanobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
GDHHQS2_k127_7146908_0	1123508.JH636439_gene1018	3.692e-120	389.0	COG3391@1|root,COG3391@2|Bacteria,2J27D@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_7146955_0	886293.Sinac_6095	5.851e-159	521.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GDHHQS2_k127_7161853_0	358220.C380_21200	1.417e-75	262.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2VKV6@28216|Betaproteobacteria,4AD8I@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_7161853_1	693986.MOC_1062	1.648e-47	177.0	COG0727@1|root,COG0727@2|Bacteria,1RJ0V@1224|Proteobacteria,2U8AG@28211|Alphaproteobacteria,1JTB8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7161896_0	1089439.KB902272_gene2269	8.589e-85	316.0	COG4990@1|root,COG4990@2|Bacteria,1R7K3@1224|Proteobacteria,1SEAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7162983_3	1144310.PMI07_006353	0.0002746	48.0	COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,4B8IY@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	antirestriction protein	ardC	-	-	-	-	-	-	-	-	-	-	-	DUF1738
GDHHQS2_k127_7162983_0	234267.Acid_2982	6.877e-194	649.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_2982|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7162983_2	234267.Acid_2840	9.83e-10	62.0	COG3485@1|root,COG3485@2|Bacteria,3Y3VM@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_7162983_1	1121396.KB893120_gene3067	4.34e-56	201.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7163160_0	234267.Acid_7841	1.666e-108	364.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_7163160_1	330214.NIDE0009	5.408e-68	244.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GDHHQS2_k127_7163701_0	639030.JHVA01000001_gene603	4.662e-265	837.0	COG1629@1|root,COG1629@2|Bacteria,3Y2JN@57723|Acidobacteria,2JI08@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7163701_2	502025.Hoch_1576	1.417e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_7163701_1	1340493.JNIF01000003_gene2949	7.706e-153	498.0	COG0642@1|root,COG0642@2|Bacteria,3Y9DC@57723|Acidobacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_7171903_0	1340493.JNIF01000003_gene3464	3.736e-178	598.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7171903_1	222984.JNCS01000002_gene882	4.161e-16	81.0	2E4PM@1|root,2N5ZN@2157|Archaea,2XY56@28890|Euryarchaeota,23W7K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7182842_0	234267.Acid_6693	1.291e-62	222.0	COG3794@1|root,COG3794@2|Bacteria,3Y4UD@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7182842_1	1267535.KB906767_gene1699	3.481e-22	103.0	COG4191@1|root,COG4191@2|Bacteria,3Y4SZ@57723|Acidobacteria,2JK9S@204432|Acidobacteriia	204432|Acidobacteriia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
GDHHQS2_k127_7187798_7	1120950.KB892767_gene5169	1.618e-19	90.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DTC9@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_7187798_4	1183438.GKIL_0967	4.89e-41	155.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_7187798_6	1183438.GKIL_0966	3.317e-20	92.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_7187798_1	204669.Acid345_0112	1.772e-174	561.0	COG1232@1|root,COG1232@2|Bacteria,3Y3KX@57723|Acidobacteria	57723|Acidobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS2_k127_7187798_0	1340493.JNIF01000004_gene667	3.233e-219	690.0	COG4262@1|root,COG4262@2|Bacteria,3Y3M2@57723|Acidobacteria	57723|Acidobacteria	S	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GDHHQS2_k127_7187798_8	1340493.JNIF01000004_gene666	1.945e-16	82.0	2EGTE@1|root,301RU@2|Bacteria,3Y93P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
GDHHQS2_k127_7187798_9	204669.Acid345_0109	3.092e-10	62.0	291F4@1|root,2ZP1Y@2|Bacteria,3Y93Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7187798_2	204669.Acid345_0108	1.15e-122	407.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS2_k127_7187798_3	204669.Acid345_0107	5.988e-79	268.0	COG1379@1|root,COG1379@2|Bacteria,3Y7H3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
GDHHQS2_k127_7187798_5	1340493.JNIF01000004_gene662	3.705e-35	139.0	COG1586@1|root,COG1586@2|Bacteria,3Y8GM@57723|Acidobacteria	57723|Acidobacteria	E	S-adenosylmethionine decarboxylase	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GDHHQS2_k127_7187798_10	1340493.JNIF01000004_gene661	0.0003166	44.0	COG4260@1|root,COG4260@2|Bacteria,3Y3NF@57723|Acidobacteria	57723|Acidobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
GDHHQS2_k127_7190891_0	234267.Acid_3848	3.798e-212	672.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_7190891_3	1340493.JNIF01000003_gene1435	8.935e-31	129.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_7190891_1	234267.Acid_3846	1.912e-53	195.0	2FCIR@1|root,344N3@2|Bacteria,3Y8MF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7190891_2	1340493.JNIF01000003_gene2637	3.694e-34	140.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,TonB_C
GDHHQS2_k127_7196508_1	234267.Acid_5004	1.596e-211	700.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_7196508_2	886293.Sinac_4622	6.828e-146	474.0	COG3119@1|root,COG3119@2|Bacteria,2IYNZ@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_7196508_4	234267.Acid_6210	9.46e-33	132.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_7196508_3	234267.Acid_7300	3.252e-56	200.0	COG0432@1|root,COG0432@2|Bacteria,3Y4YD@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS2_k127_7196508_0	671143.DAMO_1991	1.602e-238	752.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
GDHHQS2_k127_7198155_1	196490.AUEZ01000036_gene6081	3.582e-58	220.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
GDHHQS2_k127_7198155_0	402777.KB235904_gene4630	3.171e-137	450.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS2_k127_7199753_0	1340493.JNIF01000003_gene3063	0.0	1531.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GDHHQS2_k127_7199753_1	1340493.JNIF01000003_gene3064	1.988e-120	396.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
GDHHQS2_k127_7199753_2	331869.BAL199_24894	5.577e-116	383.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,4BSDH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	comC	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
GDHHQS2_k127_7199753_3	1502851.FG93_02359	9.403e-69	243.0	COG2362@1|root,COG2362@2|Bacteria,1QH4F@1224|Proteobacteria,2U3TC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GDHHQS2_k127_7199753_4	1340493.JNIF01000003_gene4327	1.226e-45	171.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
GDHHQS2_k127_7199753_5	1340493.JNIF01000003_gene4326	9.747e-44	165.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_7199753_6	1340493.JNIF01000003_gene4325	1.221e-31	129.0	2EJEF@1|root,33D5F@2|Bacteria,3Y5WQ@57723|Acidobacteria	57723|Acidobacteria	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7199753_10	926556.Echvi_1223	2.646e-11	71.0	COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_7199753_11	682795.AciX8_2512	2.47e-09	66.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7199921_4	1267533.KB906735_gene4807	8.057e-45	163.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	fabB	-	2.3.1.179,2.3.1.180	ko:K09458,ko:K18473	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00082,M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R10707	RC00004,RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_7199921_3	234267.Acid_6315	1.019e-77	280.0	COG2234@1|root,COG2234@2|Bacteria,3Y341@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_7199921_6	1033991.RLEG12_02100	4.993e-06	57.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,2TSU5@28211|Alphaproteobacteria,4B9W0@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
GDHHQS2_k127_7199921_0	1267535.KB906767_gene470	6.318e-183	581.0	COG0247@1|root,COG0247@2|Bacteria,3Y6NT@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
GDHHQS2_k127_7199921_2	234267.Acid_0451	3.259e-109	364.0	COG0277@1|root,COG0277@2|Bacteria,3Y6TT@57723|Acidobacteria	57723|Acidobacteria	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
GDHHQS2_k127_7199921_5	234267.Acid_1968	3.286e-08	64.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
GDHHQS2_k127_7199921_1	234267.Acid_6265	6.252e-158	524.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS2_k127_7211336_4	1340493.JNIF01000003_gene1288	1.132e-25	118.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS2_k127_7211336_1	281090.Lxx10605	9.947e-31	129.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4FP8X@85023|Microbacteriaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_7211336_0	309807.SRU_1258	3.183e-128	425.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS2_k127_7211336_2	234267.Acid_7573	7.772e-28	117.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7211336_3	234267.Acid_7573	1.744e-26	123.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7211336_6	401053.AciPR4_3580	4.067e-10	69.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_7211863_2	886293.Sinac_6485	2.26e-32	130.0	COG0613@1|root,COG0613@2|Bacteria,2IY27@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7211863_0	1396141.BATP01000009_gene2639	6.409e-191	602.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_7211863_1	1267535.KB906767_gene1680	4.83e-87	299.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
GDHHQS2_k127_7228508_1	1267535.KB906767_gene1738	2.17e-51	190.0	COG3829@1|root,COG3829@2|Bacteria,3Y6K2@57723|Acidobacteria	57723|Acidobacteria	KT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
GDHHQS2_k127_7228508_0	1267533.KB906739_gene2501	3.379e-107	359.0	COG2208@1|root,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_7235757_0	1121904.ARBP01000008_gene3334	2.78e-163	520.0	COG1878@1|root,COG1878@2|Bacteria,4NIR3@976|Bacteroidetes	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS2_k127_7235757_1	351016.RAZWK3B_09896	7.327e-38	149.0	COG3473@1|root,COG3473@2|Bacteria,1RKZQ@1224|Proteobacteria,2U13U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS2_k127_7236_0	330214.NIDE1291	8.39e-222	696.0	COG0210@1|root,COG0210@2|Bacteria,3J0VX@40117|Nitrospirae	40117|Nitrospirae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS2_k127_7239477_2	1205680.CAKO01000002_gene2495	5.252e-52	186.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
GDHHQS2_k127_7239477_0	143224.JQMD01000002_gene1596	8.968e-137	457.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1HZA1@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_7239477_1	234267.Acid_5313	8.325e-105	355.0	COG0845@1|root,COG0845@2|Bacteria,3Y760@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_7239477_3	234267.Acid_5314	1.055e-44	168.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_7249122_1	1340493.JNIF01000003_gene3336	6.391e-42	160.0	COG3595@1|root,COG3595@2|Bacteria,3Y5MS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_7249122_0	234267.Acid_5645	0.0	1767.0	COG1038@1|root,COG1038@2|Bacteria,3Y6UX@57723|Acidobacteria	57723|Acidobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
GDHHQS2_k127_7249122_2	313612.L8106_00900	3.919e-27	116.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2461@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_7255357_0	1122605.KB893637_gene3269	3.812e-168	557.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_7255357_1	1340493.JNIF01000004_gene502	2.527e-58	215.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_726058_3	880070.Cycma_2024	5.238e-37	145.0	2DZG0@1|root,32V9P@2|Bacteria,4NTFA@976|Bacteroidetes,47RQH@768503|Cytophagia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS2_k127_726058_2	1340493.JNIF01000003_gene2286	1.008e-55	211.0	COG5266@1|root,COG5266@2|Bacteria	2|Bacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
GDHHQS2_k127_726058_4	234267.Acid_2357	5.497e-24	101.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
GDHHQS2_k127_726058_1	1340493.JNIF01000003_gene2818	3.39e-99	332.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_726058_0	1340493.JNIF01000003_gene2817	6.736e-139	458.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_7273210_2	1122605.KB893637_gene3269	3.536e-50	197.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
GDHHQS2_k127_7273210_0	1123248.KB893381_gene946	1.37e-204	662.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes	976|Bacteroidetes	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Hydrolase_4
GDHHQS2_k127_7273210_1	639030.JHVA01000001_gene2668	1.909e-102	335.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_7273236_6	497964.CfE428DRAFT_3922	8.766e-10	63.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14588	-	-	-	-	ko00000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
GDHHQS2_k127_7273236_1	485917.Phep_0336	1.242e-126	425.0	COG2133@1|root,COG2133@2|Bacteria,4NI97@976|Bacteroidetes,1IWTQ@117747|Sphingobacteriia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_7273236_2	1120792.JAFV01000001_gene3508	6.541e-85	294.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid aldolase or racemase	dhaa	-	4.1.3.41	ko:K18425	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS2_k127_7273236_4	1123242.JH636434_gene4748	6.694e-67	238.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_7273236_5	1123229.AUBC01000004_gene3011	1.012e-50	192.0	COG1063@1|root,COG1063@2|Bacteria,1NYF5@1224|Proteobacteria,2UTGH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
GDHHQS2_k127_7273236_3	1340493.JNIF01000003_gene3499	9.691e-81	281.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_7273236_0	1267535.KB906767_gene5169	2.29e-177	569.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_7273236_7	1210884.HG799463_gene9344	1.764e-08	59.0	COG1028@1|root,COG1028@2|Bacteria,2J2P0@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_7274566_1	1340493.JNIF01000003_gene2953	6.354e-126	407.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_7274566_0	234267.Acid_3523	1.5e-322	1024.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_7282351_0	1232437.KL661985_gene3563	3.518e-127	424.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,42RYP@68525|delta/epsilon subdivisions,2WNDE@28221|Deltaproteobacteria,2MK5X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,3.5.1.99	ko:K01426,ko:K19176	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS2_k127_7286626_0	344747.PM8797T_19819	1.622e-160	520.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_7286626_1	344747.PM8797T_15948	2.092e-87	296.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_7288531_0	234267.Acid_0871	3.058e-47	176.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	234267.Acid_0871|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_7288531_2	886293.Sinac_6975	1.214e-16	93.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7288531_1	1267535.KB906767_gene3986	5.531e-27	123.0	COG0720@1|root,COG0720@2|Bacteria,3Y4K2@57723|Acidobacteria,2JJD0@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS2_k127_7290244_0	330214.NIDE3786	6.432e-96	324.0	COG0474@1|root,COG0474@2|Bacteria,3J0WH@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS2_k127_7290244_1	330214.NIDE3783	3.31e-30	125.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,GGDEF
GDHHQS2_k127_7290244_2	330214.NIDE0866	1.493e-07	54.0	COG2854@1|root,COG2854@2|Bacteria,3J13Z@40117|Nitrospirae	40117|Nitrospirae	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
GDHHQS2_k127_7290244_3	330214.NIDE3775	1.674e-06	49.0	COG2010@1|root,COG2010@2|Bacteria,3J1AX@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
GDHHQS2_k127_729075_0	234267.Acid_0841	1.066e-226	719.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS2_k127_729075_2	401053.AciPR4_0369	8.874e-41	163.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS2_k127_729075_1	861299.J421_6282	2.996e-155	504.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
GDHHQS2_k127_7296846_0	234267.Acid_3066	6.406e-101	355.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_743939_3	234267.Acid_6875	1.323e-19	93.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_743939_2	1123504.JQKD01000030_gene4621	4.947e-21	100.0	COG3409@1|root,COG3409@2|Bacteria,1NQDV@1224|Proteobacteria	1224|Proteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_743939_1	1267535.KB906767_gene5301	1.531e-37	147.0	COG4636@1|root,COG4636@2|Bacteria,3Y7WQ@57723|Acidobacteria,2JN0R@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_743939_0	1220535.IMCC14465_18640	2.427e-115	387.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,4BT88@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS2_k127_754485_2	1298863.AUEP01000003_gene2720	0.0004742	44.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
GDHHQS2_k127_754485_1	1163617.SCD_n01370	3.662e-62	218.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,2VYEF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_754485_0	314345.SPV1_02292	4.664e-260	805.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria	1224|Proteobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,Pyr_redox_3
GDHHQS2_k127_759203_0	1121957.ATVL01000010_gene356	4.486e-97	324.0	2CCP0@1|root,2Z7XN@2|Bacteria,4NPNV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_759203_1	1267533.KB906740_gene280	7.553e-64	239.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,CBM_4_9,DUF3466,FG-GAP_2
GDHHQS2_k127_759203_2	861299.J421_0617	2.893e-21	100.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_759203_3	1394178.AWOO02000102_gene8257	2.106e-09	63.0	COG3386@1|root,COG3386@2|Bacteria,2HDRT@201174|Actinobacteria,4EG50@85012|Streptosporangiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
GDHHQS2_k127_759640_1	234267.Acid_7666	2.898e-105	351.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_759640_0	1123073.KB899241_gene2108	1.612e-263	846.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
GDHHQS2_k127_76210_0	1123278.KB893615_gene5179	5.09e-123	419.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_76210_1	234267.Acid_1104	4.765e-14	74.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_768718_0	1192034.CAP_8450	5.054e-77	269.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
GDHHQS2_k127_769610_1	1340493.JNIF01000004_gene969	5.181e-171	545.0	COG4206@1|root,COG4206@2|Bacteria,3Y30M@57723|Acidobacteria	57723|Acidobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_769610_0	234267.Acid_6871	1.348e-179	603.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_769610_4	1499967.BAYZ01000007_gene5399	3.79e-54	201.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS2_k127_769610_5	926566.Terro_1167	2.199e-52	195.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_769610_3	234267.Acid_6723	4.762e-86	289.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS2_k127_769610_2	234267.Acid_6722	1.689e-137	446.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_771603_3	1313172.YM304_03450	3.587e-09	71.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	MA20_05265	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_771603_2	237368.SCABRO_02775	1.57e-09	72.0	COG1361@1|root,COG3023@1|root,COG3064@1|root,COG3266@1|root,COG4412@1|root,COG1361@2|Bacteria,COG3023@2|Bacteria,COG3064@2|Bacteria,COG3266@2|Bacteria,COG4412@2|Bacteria,2J4CI@203682|Planctomycetes	203682|Planctomycetes	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
GDHHQS2_k127_771603_1	1340493.JNIF01000003_gene2911	1.391e-25	125.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_771603_0	316274.Haur_3299	5.156e-69	266.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CAP,HemolysinCabind,LGFP,VanY
GDHHQS2_k127_779075_3	886293.Sinac_0976	2.181e-07	55.0	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
GDHHQS2_k127_779075_2	886293.Sinac_0977	1.03e-15	80.0	COG3668@1|root,COG3668@2|Bacteria,2J4SU@203682|Planctomycetes	2|Bacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_779075_0	1123242.JH636435_gene3077	1.052e-164	523.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS2_k127_779075_1	1122194.AUHU01000004_gene1454	6.267e-144	470.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,4662I@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Protein of unknown function (DUF3417)	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS2_k127_77948_0	204669.Acid345_3887	5.49e-194	631.0	COG0577@1|root,COG0577@2|Bacteria,3Y36E@57723|Acidobacteria,2JHJ3@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_77948_2	240015.ACP_2126	1.78e-35	149.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_77948_1	234267.Acid_1508	2.299e-125	408.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GDHHQS2_k127_780581_3	395493.BegalDRAFT_2540	3.17e-36	143.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,461A5@72273|Thiotrichales	72273|Thiotrichales	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
GDHHQS2_k127_780581_4	1340493.JNIF01000003_gene3187	5.228e-09	63.0	2EFVI@1|root,339MS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_780581_0	1247726.MIM_c34270	5.666e-131	431.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2WA0B@28216|Betaproteobacteria,3T4XD@506|Alcaligenaceae	28216|Betaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
GDHHQS2_k127_780581_1	1247726.MIM_c34280	2.619e-89	303.0	2EMGW@1|root,33F5I@2|Bacteria,1R5ZH@1224|Proteobacteria	1224|Proteobacteria	L	Restriction endonuclease NotI	-	-	-	-	-	-	-	-	-	-	-	-	NotI
GDHHQS2_k127_780581_2	234267.Acid_1687	5.016e-52	186.0	COG3727@1|root,COG3727@2|Bacteria,3Y5S2@57723|Acidobacteria	57723|Acidobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
GDHHQS2_k127_780581_5	234267.Acid_0470	3.972e-07	54.0	COG1361@1|root,COG3391@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
GDHHQS2_k127_781753_0	652103.Rpdx1_3844	0.0	1223.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	aldehyde-lyase activity	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
GDHHQS2_k127_781753_7	215803.DB30_6428	1.045e-28	130.0	2EEXH@1|root,338QV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
GDHHQS2_k127_781753_1	234267.Acid_2208	4.173e-210	663.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria	57723|Acidobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
GDHHQS2_k127_781753_2	1267535.KB906767_gene4008	3.117e-186	589.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS2_k127_781753_6	1382359.JIAL01000001_gene130	3.846e-40	153.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria,2JJNM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_781753_4	1340493.JNIF01000004_gene730	4.713e-100	339.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
GDHHQS2_k127_781753_3	1340493.JNIF01000004_gene731	2.744e-148	492.0	COG0642@1|root,COG4252@1|root,COG2205@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	phoR_2	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,PAS_4
GDHHQS2_k127_781753_5	1278073.MYSTI_01220	1.119e-97	334.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla28	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_785413_0	1340493.JNIF01000003_gene3710	4.786e-124	402.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS2_k127_785413_2	1340493.JNIF01000003_gene3710	4.671e-17	82.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS2_k127_785413_1	234267.Acid_4553	1.56e-80	273.0	COG0836@1|root,COG0836@2|Bacteria,3Y2W2@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS2_k127_787243_0	1340493.JNIF01000003_gene4598	4.483e-140	453.0	COG2271@1|root,COG2271@2|Bacteria,3Y6U9@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_787243_1	1340493.JNIF01000003_gene4600	1.523e-133	438.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_796504_0	234267.Acid_4577	1.766e-177	567.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
GDHHQS2_k127_796504_2	367336.OM2255_05550	5.085e-36	147.0	COG3971@1|root,COG3971@2|Bacteria	2|Bacteria	Q	2-oxopent-4-enoate hydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_796504_1	309800.C498_02470	4.677e-116	391.0	COG3534@1|root,arCOG10185@2157|Archaea,2XUX4@28890|Euryarchaeota,23TE1@183963|Halobacteria	183963|Halobacteria	G	COG3534 Alpha-L-arabinofuranosidase	xsa	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
GDHHQS2_k127_799464_2	530564.Psta_2300	2.039e-73	258.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_799464_1	886293.Sinac_3795	1.505e-73	267.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GDHHQS2_k127_799464_4	1121875.KB907559_gene534	2.533e-59	219.0	COG0657@1|root,COG0657@2|Bacteria,4NZNT@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GDHHQS2_k127_799464_5	1137271.AZUM01000004_gene4083	6.211e-15	79.0	COG0346@1|root,COG0346@2|Bacteria,2IHR7@201174|Actinobacteria,4E4UI@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_799464_0	234267.Acid_5133	5.506e-111	376.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	serA5	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_799464_3	1380394.JADL01000007_gene4450	5.558e-70	256.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,2JYB7@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_799464_7	1510531.JQJJ01000012_gene1764	0.0004255	52.0	COG0346@1|root,COG0346@2|Bacteria,1RB65@1224|Proteobacteria,2U7DP@28211|Alphaproteobacteria,3JYA1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_35640	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_799464_6	929558.SMGD1_2593	0.0002141	51.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,42MHA@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
GDHHQS2_k127_808634_4	234267.Acid_6512	2.317e-153	487.0	COG0175@1|root,COG0175@2|Bacteria,3Y36I@57723|Acidobacteria	57723|Acidobacteria	EH	TIGRFAM sulfate adenylyltransferase, small subunit	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
GDHHQS2_k127_808634_3	234267.Acid_6513	4.327e-179	576.0	COG2895@1|root,COG2895@2|Bacteria,3Y3AW@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
GDHHQS2_k127_808634_5	869210.Marky_1868	6.463e-91	304.0	COG0175@1|root,COG0175@2|Bacteria,1WJU2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EH	Reduction of activated sulfate into sulfite	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
GDHHQS2_k127_808634_6	743525.TSC_c11750	1.974e-60	218.0	COG0730@1|root,COG0730@2|Bacteria,1WI3T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_808634_0	234267.Acid_4539	0.0	1079.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
GDHHQS2_k127_808634_2	1123072.AUDH01000033_gene1991	4.867e-198	627.0	COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,2U2ED@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
GDHHQS2_k127_808634_1	234267.Acid_4983	2.024e-203	651.0	COG1620@1|root,COG1620@2|Bacteria,3Y2ZA@57723|Acidobacteria	57723|Acidobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
GDHHQS2_k127_818002_0	240016.ABIZ01000001_gene3608	0.0	1263.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,2ITTI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS2_k127_818002_2	1250232.JQNJ01000001_gene1869	5.285e-166	543.0	COG4733@1|root,COG4733@2|Bacteria,4PNY1@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
GDHHQS2_k127_818002_3	1267535.KB906767_gene4678	1.184e-145	471.0	COG1092@1|root,COG1092@2|Bacteria,3Y2PV@57723|Acidobacteria,2JICM@204432|Acidobacteriia	204432|Acidobacteriia	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS2_k127_818002_5	1267535.KB906767_gene2673	4.402e-109	359.0	COG0501@1|root,COG0501@2|Bacteria,3Y3EZ@57723|Acidobacteria,2JIIZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS2_k127_818002_6	1336243.JAEA01000006_gene368	5.464e-28	123.0	COG2885@1|root,COG2885@2|Bacteria,1PE6U@1224|Proteobacteria,2UBKQ@28211|Alphaproteobacteria,1JWQF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS2_k127_818002_1	1340493.JNIF01000004_gene419	9.354e-205	651.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS2_k127_818002_4	1340493.JNIF01000003_gene1816	4.936e-119	389.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	He_PIG,NHL,SGL
GDHHQS2_k127_827605_0	234267.Acid_3106	1.072e-261	818.0	28HBM@1|root,2Z7NK@2|Bacteria,3Y6H0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_827605_2	234267.Acid_2234	8.798e-165	555.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	aspB1	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS2_k127_827605_3	1267535.KB906767_gene2038	1.625e-07	56.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
GDHHQS2_k127_827605_1	234267.Acid_4431	2.162e-210	683.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_831244_1	234267.Acid_6834	6.415e-70	256.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_831244_0	234267.Acid_5471	1.247e-132	450.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS2_k127_831374_0	1340493.JNIF01000003_gene3464	4.955e-114	385.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_831374_2	1267535.KB906767_gene223	5.806e-06	53.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_831374_1	306281.AJLK01000032_gene1577	1.737e-08	55.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_832251_0	1267535.KB906767_gene3524	2.918e-211	696.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_832251_1	1038866.KB902774_gene2221	0.0001018	47.0	COG4932@1|root,COG5563@1|root,COG4932@2|Bacteria,COG5563@2|Bacteria,1N5JV@1224|Proteobacteria,2UD1J@28211|Alphaproteobacteria,3K0ME@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_84244_0	760117.JN27_17825	7.902e-151	486.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VI1T@28216|Betaproteobacteria,47403@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
GDHHQS2_k127_84244_2	667632.KB890187_gene3218	3.344e-55	200.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2VRNU@28216|Betaproteobacteria,1KG4I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_84244_3	1336243.JAEA01000001_gene1725	9.756e-33	140.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,2U21F@28211|Alphaproteobacteria,1JW99@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
GDHHQS2_k127_84244_1	1340493.JNIF01000004_gene405	1.167e-116	379.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_843908_7	593117.TGAM_0774	2.145e-06	55.0	COG3291@1|root,arCOG03396@2157|Archaea,2Y2XK@28890|Euryarchaeota,242ST@183968|Thermococci	183968|Thermococci	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GDHHQS2_k127_843908_6	204669.Acid345_4048	3.906e-16	80.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_843908_5	1340493.JNIF01000003_gene4745	5.572e-26	109.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_843908_2	1267535.KB906767_gene5233	9.148e-53	198.0	COG2823@1|root,COG2823@2|Bacteria,3Y7GR@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_843908_3	234267.Acid_6975	1.906e-43	164.0	2CBEY@1|root,33YTG@2|Bacteria,3Y88I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_843908_4	1267535.KB906767_gene5098	7.489e-42	158.0	2FGSP@1|root,348N1@2|Bacteria,3Y8G3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_843908_1	234267.Acid_1522	6.371e-103	338.0	COG2041@1|root,COG2041@2|Bacteria,3Y85H@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_843908_8	765911.Thivi_4348	0.0001598	51.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,1RNUW@1236|Gammaproteobacteria,1WVWK@135613|Chromatiales	135613|Chromatiales	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GDHHQS2_k127_843908_0	1340493.JNIF01000004_gene1083	1.488e-136	459.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_856505_0	234267.Acid_4384	2.805e-70	244.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_865652_0	314230.DSM3645_08942	3.155e-179	569.0	COG0405@1|root,COG0405@2|Bacteria,2IWWP@203682|Planctomycetes	203682|Planctomycetes	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_865652_1	502025.Hoch_1577	1.309e-27	120.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_868841_0	234267.Acid_3122	4.02e-113	387.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	2|Bacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_868841_1	1340493.JNIF01000003_gene2735	1.171e-92	321.0	COG2304@1|root,COG2304@2|Bacteria,3Y8A4@57723|Acidobacteria	57723|Acidobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_868841_2	1267534.KB906755_gene4541	5.001e-52	205.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y2PF@57723|Acidobacteria,2JIIF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_876290_1	1267535.KB906767_gene904	9.484e-84	290.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
GDHHQS2_k127_876290_5	1254432.SCE1572_00290	0.0005136	48.0	COG0517@1|root,COG0517@2|Bacteria,1QZT1@1224|Proteobacteria,43CN4@68525|delta/epsilon subdivisions,2X7VC@28221|Deltaproteobacteria,2Z3IG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_876290_3	502025.Hoch_4458	9.401e-16	87.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
GDHHQS2_k127_876290_2	1254432.SCE1572_00290	1.398e-17	86.0	COG0517@1|root,COG0517@2|Bacteria,1QZT1@1224|Proteobacteria,43CN4@68525|delta/epsilon subdivisions,2X7VC@28221|Deltaproteobacteria,2Z3IG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_876290_0	234267.Acid_6976	5.042e-188	608.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_876290_4	1201293.AKXQ01000002_gene1850	1.288e-10	66.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
GDHHQS2_k127_876472_1	1340493.JNIF01000003_gene1501	1.545e-107	371.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,VIT,VWA_3
GDHHQS2_k127_876472_2	1340493.JNIF01000003_gene1500	1.753e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_876472_0	1340493.JNIF01000003_gene3556	4.324e-191	605.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_879939_3	1047013.AQSP01000106_gene1763	7.682e-06	55.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_879939_1	1267535.KB906767_gene4768	2.006e-142	465.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_879939_0	886293.Sinac_6825	1.047e-167	537.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS2_k127_879939_2	234267.Acid_7510	1.01e-90	325.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_891395_1	8479.XP_005293092.2	8.725e-08	61.0	COG0666@1|root,KOG4177@2759|Eukaryota,39TNQ@33154|Opisthokonta,3BCVG@33208|Metazoa,3D33I@33213|Bilateria,47ZV4@7711|Chordata,494QG@7742|Vertebrata,4CCY9@8459|Testudines	33208|Metazoa	M	ankyrin repeat	ANKRD65	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
GDHHQS2_k127_891395_0	1267535.KB906767_gene4711	3.597e-269	861.0	COG4932@1|root,COG4932@2|Bacteria,3Y6EM@57723|Acidobacteria,2JKUS@204432|Acidobacteriia	204432|Acidobacteriia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_892246_2	107635.AZUO01000001_gene1405	2.777e-34	136.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2UEV4@28211|Alphaproteobacteria,370A0@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
GDHHQS2_k127_892246_0	234267.Acid_3496	4.272e-225	710.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_892246_1	344747.PM8797T_08574	1.066e-68	237.0	COG4225@1|root,COG4225@2|Bacteria,2IZFK@203682|Planctomycetes	203682|Planctomycetes	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
GDHHQS2_k127_914604_2	886293.Sinac_4683	4.636e-48	179.0	COG0457@1|root,COG0457@2|Bacteria	886293.Sinac_4683|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
GDHHQS2_k127_914604_1	582744.Msip34_1286	2.469e-151	492.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
GDHHQS2_k127_914604_0	313603.FB2170_05385	1.324e-173	570.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia,2PIWB@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_914651_2	1340493.JNIF01000004_gene404	7.394e-167	528.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
GDHHQS2_k127_914651_4	1123229.AUBC01000031_gene255	1.028e-13	74.0	COG2131@1|root,COG2131@2|Bacteria,1PMV0@1224|Proteobacteria,2U2JZ@28211|Alphaproteobacteria,3K3N5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GDHHQS2_k127_914651_1	240015.ACP_0733	3.01e-189	604.0	COG2759@1|root,COG2759@2|Bacteria,3Y338@57723|Acidobacteria,2JMF8@204432|Acidobacteriia	204432|Acidobacteriia	H	Formate--tetrahydrofolate ligase	-	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
GDHHQS2_k127_914651_0	1340493.JNIF01000003_gene3571	4.039e-214	671.0	COG4948@1|root,COG4948@2|Bacteria,3Y624@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_914651_3	1210884.HG799468_gene13605	3.416e-111	389.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
GDHHQS2_k127_919433_1	1242864.D187_002269	1.038e-82	282.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2WM9T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Peptidase M20	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_919433_0	530564.Psta_3103	4.109e-95	321.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_920592_0	1267535.KB906767_gene711	0.0	1257.0	COG4932@1|root,COG4932@2|Bacteria,3Y6EM@57723|Acidobacteria,2JKUS@204432|Acidobacteriia	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS2_k127_920592_3	1267535.KB906767_gene657	2.987e-80	274.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria,2JHRB@204432|Acidobacteriia	2|Bacteria	G	Inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K05602,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_920592_5	1340493.JNIF01000003_gene4552	6.811e-70	246.0	COG0266@1|root,COG0266@2|Bacteria,3Y39U@57723|Acidobacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS2_k127_920592_2	204669.Acid345_1464	4.065e-198	640.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria,2JKP3@204432|Acidobacteriia	204432|Acidobacteriia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_920592_8	596152.DesU5LDRAFT_0796	0.0004154	50.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
GDHHQS2_k127_920592_1	1340493.JNIF01000003_gene3464	5.665e-237	773.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Q@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_920592_4	1340493.JNIF01000003_gene4459	4.823e-72	249.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	tdcF2	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
GDHHQS2_k127_927001_3	1340493.JNIF01000003_gene3642	6.898e-122	398.0	COG0489@1|root,COG0489@2|Bacteria,3Y66Z@57723|Acidobacteria	57723|Acidobacteria	D	AAA domain	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS2_k127_927001_1	1340493.JNIF01000003_gene3643	9.256e-139	460.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	GNVR,Wzz
GDHHQS2_k127_927001_7	1340493.JNIF01000003_gene3644	2.76e-58	211.0	COG1596@1|root,COG1596@2|Bacteria,3Y51C@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS2_k127_927001_8	234267.Acid_2578	1.337e-46	171.0	COG2947@1|root,COG2947@2|Bacteria,3Y54W@57723|Acidobacteria	57723|Acidobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS2_k127_927001_4	452662.SJA_C2-00890	2.48e-114	385.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U3G1@28211|Alphaproteobacteria,2K3ZD@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_927001_6	1267535.KB906767_gene5198	1.038e-61	222.0	COG2071@1|root,COG2071@2|Bacteria,3Y5MA@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS2_k127_927001_2	234267.Acid_7065	4.303e-123	404.0	28M67@1|root,31CRD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_927001_9	1408813.AYMG01000027_gene5295	1.05e-24	112.0	COG2318@1|root,COG2318@2|Bacteria,4NX8X@976|Bacteroidetes,1IU1A@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_927001_5	1254432.SCE1572_04430	4.401e-93	321.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
GDHHQS2_k127_927001_0	448385.sce0660	3.05e-140	470.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
GDHHQS2_k127_927001_10	163908.KB235896_gene608	5.656e-17	91.0	COG2337@1|root,COG2337@2|Bacteria,1GIQZ@1117|Cyanobacteria,1HPA0@1161|Nostocales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_927001_11	234267.Acid_1341	8.966e-10	61.0	COG0454@1|root,COG0456@2|Bacteria,3Y5H6@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_927498_2	1340493.JNIF01000003_gene2530	5.754e-163	526.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GDHHQS2_k127_927498_0	234267.Acid_3964	3.679e-296	940.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y7IX@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HAMP,Pkinase
GDHHQS2_k127_927498_4	1340493.JNIF01000004_gene502	1.168e-86	296.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_927498_1	221288.JH992901_gene3895	2.77e-174	554.0	COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria	1117|Cyanobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
GDHHQS2_k127_927498_6	1391646.AVSU01000001_gene205	8.741e-22	106.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,248TA@186801|Clostridia	186801|Clostridia	CP	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,Abi
GDHHQS2_k127_927498_7	797114.C475_21899	1.01e-12	76.0	COG1661@1|root,arCOG04212@2157|Archaea,2XWU3@28890|Euryarchaeota,23V52@183963|Halobacteria	183963|Halobacteria	S	DNA-binding protein with PD1-like DNA-binding motif	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
GDHHQS2_k127_927498_5	1267535.KB906767_gene4919	3.274e-74	271.0	COG0745@1|root,COG0745@2|Bacteria,3Y67W@57723|Acidobacteria	57723|Acidobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_927498_3	1340493.JNIF01000003_gene4600	2.81e-104	350.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_930059_3	234267.Acid_3225	1.841e-16	87.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
GDHHQS2_k127_930059_1	298653.Franean1_4088	1.272e-19	105.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cu_amine_oxidN1,NHL,Pkinase
GDHHQS2_k127_930059_0	88036.EFJ18964	2.937e-25	120.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
GDHHQS2_k127_930059_2	88036.EFJ16006	8.458e-17	94.0	2CNBU@1|root,2QV2U@2759|Eukaryota,37T4I@33090|Viridiplantae,3GFEA@35493|Streptophyta	35493|Streptophyta	S	Leucine-rich repeat (LRR) family protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,LRR_8
GDHHQS2_k127_938368_6	237368.SCABRO_03102	1.02e-21	103.0	COG1262@1|root,COG1262@2|Bacteria,2J4RS@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_938368_2	886293.Sinac_3304	2.132e-114	385.0	COG4102@1|root,COG4102@2|Bacteria,2IXDD@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_938368_0	1210884.HG799470_gene14286	6.412e-162	535.0	COG5492@1|root,COG5492@2|Bacteria,2J1SU@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_938368_1	344747.PM8797T_15706	2.471e-155	517.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_938368_5	1254432.SCE1572_32985	1.977e-58	227.0	COG3591@1|root,COG3591@2|Bacteria,1N5ID@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
GDHHQS2_k127_938368_7	1340493.JNIF01000004_gene670	7.081e-05	56.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,Calx-beta,Laminin_G_3,PA14,VPEP
GDHHQS2_k127_938368_4	1340493.JNIF01000003_gene4051	1.703e-73	252.0	COG0615@1|root,COG0615@2|Bacteria,3Y5F4@57723|Acidobacteria	57723|Acidobacteria	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GDHHQS2_k127_938368_3	1267535.KB906767_gene1342	7.91e-94	319.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS2_k127_940386_0	1267535.KB906767_gene2487	3.859e-285	898.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	57723|Acidobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS2_k127_940386_1	1340493.JNIF01000003_gene3823	4.644e-80	274.0	COG0457@1|root,COG0457@2|Bacteria,3Y5A8@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_941898_4	234267.Acid_7548	2.354e-05	48.0	COG1453@1|root,COG1453@2|Bacteria,3Y6QH@57723|Acidobacteria	57723|Acidobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_941898_0	1340493.JNIF01000003_gene4600	9.576e-232	758.0	COG1629@1|root,COG4771@2|Bacteria,3Y66U@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_941898_5	714943.Mucpa_7167	0.0006163	49.0	COG1208@1|root,COG3420@1|root,COG5184@1|root,COG5492@1|root,COG1208@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NMRB@976|Bacteroidetes,1ITFX@117747|Sphingobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,Flg_new
GDHHQS2_k127_941898_2	1340493.JNIF01000004_gene94	5.428e-106	358.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_941898_1	530564.Psta_2567	2.709e-121	397.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GDHHQS2_k127_941898_3	1267535.KB906767_gene748	1.236e-36	140.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria,2JHTF@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS2_k127_943152_2	234267.Acid_1017	4.889e-52	192.0	COG0312@1|root,COG0312@2|Bacteria,3Y39N@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS2_k127_943152_1	1267535.KB906767_gene4537	3.848e-68	233.0	COG0328@1|root,COG1057@1|root,COG0328@2|Bacteria,COG1057@2|Bacteria,3Y5D2@57723|Acidobacteria,2JJNT@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS2_k127_943152_3	1123508.JH636439_gene1117	4.736e-48	185.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_943152_5	1198114.AciX9_2866	3.909e-42	165.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_943152_6	204669.Acid345_0871	2.289e-25	117.0	COG3058@1|root,COG3058@2|Bacteria,3Y87B@57723|Acidobacteria	57723|Acidobacteria	O	protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
GDHHQS2_k127_943152_4	204669.Acid345_0870	2.354e-44	168.0	COG2864@1|root,COG2864@2|Bacteria,3Y884@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
GDHHQS2_k127_943152_0	243233.MCA1209	3.634e-101	335.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1RNFG@1236|Gammaproteobacteria,1XFU7@135618|Methylococcales	135618|Methylococcales	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Form-deh_trans
GDHHQS2_k127_94531_0	278963.ATWD01000002_gene750	7.866e-261	824.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Q2@57723|Acidobacteria,2JM5C@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_948063_1	886293.Sinac_0399	1.319e-18	87.0	COG0657@1|root,COG0657@2|Bacteria,2IWRZ@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
GDHHQS2_k127_948063_0	1267534.KB906756_gene590	7.918e-262	811.0	COG0174@1|root,COG0174@2|Bacteria,3Y2P8@57723|Acidobacteria,2JHXX@204432|Acidobacteriia	204432|Acidobacteriia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS2_k127_948936_7	234267.Acid_7424	7.917e-52	186.0	COG0607@1|root,COG0607@2|Bacteria,3Y5RG@57723|Acidobacteria	57723|Acidobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_948936_2	234267.Acid_6725	7.314e-184	596.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_948936_4	234267.Acid_6726	7.05e-130	421.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS2_k127_948936_0	234267.Acid_2270	3.722e-311	985.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_948936_3	1340493.JNIF01000003_gene3299	1.063e-131	427.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_948936_5	1340493.JNIF01000003_gene3298	6.337e-114	379.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS2_k127_948936_1	1340493.JNIF01000003_gene3297	1.226e-238	741.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS2_k127_950390_2	1510531.JQJJ01000008_gene3255	1.586e-63	224.0	COG4104@1|root,COG4104@2|Bacteria,1RDB0@1224|Proteobacteria,2U8I2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
GDHHQS2_k127_950390_4	234267.Acid_1280	4.935e-44	173.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_950390_1	1267535.KB906767_gene1422	3.603e-92	306.0	COG0262@1|root,COG0262@2|Bacteria,3Y4XB@57723|Acidobacteria,2JMVD@204432|Acidobacteriia	204432|Acidobacteriia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_950390_3	1173022.Cri9333_0955	5.458e-54	196.0	COG4636@1|root,COG4636@2|Bacteria,1G13A@1117|Cyanobacteria,1H8G1@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_950390_7	357808.RoseRS_1412	1.163e-19	94.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_950390_5	1267535.KB906767_gene4941	4.859e-39	152.0	COG1595@1|root,COG1595@2|Bacteria,3Y5K8@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_950390_6	1267535.KB906767_gene4943	3.298e-23	108.0	291QZ@1|root,2ZPB0@2|Bacteria,3Y92F@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_950390_0	1123242.JH636434_gene4912	1.032e-138	461.0	COG1053@1|root,COG1053@2|Bacteria,2J3SP@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
GDHHQS2_k127_950390_8	234267.Acid_0472	8.787e-13	72.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
GDHHQS2_k127_951620_1	234267.Acid_0870	2.142e-48	182.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
GDHHQS2_k127_951620_0	1267533.KB906733_gene3472	6.464e-150	510.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
GDHHQS2_k127_954896_0	234267.Acid_7679	3.845e-112	397.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_954913_3	497964.CfE428DRAFT_0240	4.278e-08	58.0	COG4102@1|root,COG4102@2|Bacteria,46UFC@74201|Verrucomicrobia	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_954913_1	1048339.KB913029_gene1811	1.402e-30	126.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria,4EWYP@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_954913_0	234267.Acid_4060	4.668e-149	476.0	COG4102@1|root,COG4102@2|Bacteria,3Y6RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_954941_0	278963.ATWD01000001_gene1304	2.092e-135	458.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_962580_0	234267.Acid_0751	1.239e-254	812.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS2_k127_971133_0	234267.Acid_6547	4.098e-250	794.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_971133_2	251221.35212708	2.048e-13	74.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
GDHHQS2_k127_971133_1	234267.Acid_6678	9.432e-53	194.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_976126_2	1340493.JNIF01000004_gene1050	9.667e-89	299.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_976126_0	926556.Echvi_1434	6.469e-131	427.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GDHHQS2_k127_976126_1	1267535.KB906767_gene4416	6.683e-123	400.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
GDHHQS2_k127_976126_4	1382359.JIAL01000001_gene2207	1.753e-46	171.0	COG2905@1|root,COG2905@2|Bacteria,3Y5NG@57723|Acidobacteria,2JN0N@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_976126_3	1340493.JNIF01000004_gene980	2.041e-48	180.0	COG2823@1|root,COG2823@2|Bacteria,3Y41W@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_982402_1	1480694.DC28_01060	1.992e-10	75.0	COG1470@1|root,COG1470@2|Bacteria,2JAW0@203691|Spirochaetes	203691|Spirochaetes	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
GDHHQS2_k127_982402_0	234267.Acid_4576	3.729e-26	120.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_984611_0	357808.RoseRS_1479	9.293e-142	457.0	COG0553@1|root,COG0553@2|Bacteria,2G6I4@200795|Chloroflexi,376H9@32061|Chloroflexia	32061|Chloroflexia	KL	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2
GDHHQS2_k127_984611_1	357808.RoseRS_1478	5.247e-45	168.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2G84A@200795|Chloroflexi,376BB@32061|Chloroflexia	200795|Chloroflexi	LV	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_986150_0	1340493.JNIF01000003_gene3902	1.046e-250	794.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GDHHQS2_k127_993482_0	682795.AciX8_3257	7.985e-135	447.0	COG3485@1|root,COG3485@2|Bacteria,3Y3R9@57723|Acidobacteria,2JHNH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_993482_1	1123508.JH636439_gene499	1.834e-94	320.0	COG2010@1|root,COG2010@2|Bacteria,2IXUQ@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
GDHHQS2_k127_996481_1	671143.DAMO_2078	3.462e-36	147.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_996481_0	861299.J421_2622	4.74e-151	483.0	COG1158@1|root,COG1158@2|Bacteria,1ZSXH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS2_k127_99801_4	1210884.HG799463_gene10110	1.832e-07	57.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
GDHHQS2_k127_99801_0	1123508.JH636440_gene2035	1.587e-124	406.0	COG0451@1|root,COG0451@2|Bacteria,2IXJ5@203682|Planctomycetes	203682|Planctomycetes	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_99801_1	1210884.HG799463_gene10111	1.222e-93	337.0	COG0438@1|root,COG0438@2|Bacteria,2IYFU@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_99801_3	215803.DB30_1976	7.12e-57	225.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2YVJ5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GDHHQS2_k127_99801_2	886293.Sinac_2477	4.321e-64	226.0	COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
## 7057 queries scanned
## Total time (seconds): 32.635438680648804
## Rate: 216.24 q/s