## Mon Feb 16 20:50:27 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/GDHHQS2_bin.59.fa -m mmseqs --output GDHHQS2_bin.59 --output_dir /data/result/bins/wyx/eggqs50+/GDHHQS2_bin.59 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS2_k127_100534_0	234267.Acid_7087	2.879e-109	362.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
GDHHQS2_k127_100534_1	518766.Rmar_1377	4.047e-41	158.0	COG3019@1|root,COG3019@2|Bacteria,4P644@976|Bacteroidetes,1FJE9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
GDHHQS2_k127_100534_2	1379270.AUXF01000001_gene2468	1.123e-18	93.0	COG2318@1|root,COG2318@2|Bacteria,1ZV11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_100534_3	1101188.KI912155_gene3682	1.026e-12	77.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
GDHHQS2_k127_1017677_22	379066.GAU_1450	7.402e-46	167.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
GDHHQS2_k127_1017677_23	477974.Daud_2046	1.121e-34	138.0	COG0295@1|root,COG0319@1|root,COG0295@2|Bacteria,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
GDHHQS2_k127_1017677_17	379066.GAU_1452	2.241e-65	241.0	2F0K0@1|root,33TNP@2|Bacteria,1ZTJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1017677_18	861299.J421_3097	2.556e-63	233.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1017677_8	861299.J421_3098	1.018e-165	529.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_3098|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1017677_3	861299.J421_3101	6.358e-210	659.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS2_k127_1017677_5	861299.J421_3104	7.579e-192	620.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
GDHHQS2_k127_1017677_7	1379270.AUXF01000005_gene710	2.435e-169	541.0	COG0158@1|root,COG0158@2|Bacteria,1ZTAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
GDHHQS2_k127_1017677_0	861299.J421_3107	6.061e-254	792.0	COG1884@1|root,COG1884@2|Bacteria,1ZT5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS2_k127_1017677_27	861299.J421_3109	7.368e-19	92.0	COG2331@1|root,COG2331@2|Bacteria,1ZU2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1017677_2	379066.GAU_1467	1.793e-247	774.0	COG0018@1|root,COG0018@2|Bacteria,1ZT6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS2_k127_1017677_10	1379270.AUXF01000005_gene720	2.334e-152	486.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS2_k127_1017677_11	861299.J421_3112	3.021e-149	481.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_1017677_15	861299.J421_3113	6.641e-94	318.0	2F30H@1|root,33VVT@2|Bacteria,1ZTRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1017677_13	861299.J421_3114	3.677e-111	371.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS2_k127_1017677_16	1379270.AUXF01000005_gene724	1.796e-74	255.0	COG0307@1|root,COG0307@2|Bacteria,1ZTQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS2_k127_1017677_4	861299.J421_3116	3.171e-197	624.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GDHHQS2_k127_1017677_19	861299.J421_3117	1.616e-61	215.0	COG0054@1|root,COG0054@2|Bacteria,1ZTPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS2_k127_1017677_21	861299.J421_3118	3.131e-51	188.0	COG0781@1|root,COG0781@2|Bacteria,1ZTRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS2_k127_1017677_9	861299.J421_3119	1.005e-156	503.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1017677_12	379066.GAU_1477	2.274e-131	429.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
GDHHQS2_k127_1017677_25	861299.J421_3122	1.121e-28	120.0	COG2893@1|root,COG2893@2|Bacteria,1ZU41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
GDHHQS2_k127_1017677_20	861299.J421_3123	3.782e-60	218.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
GDHHQS2_k127_1017677_28	1144275.COCOR_07126	7.501e-05	53.0	COG3715@1|root,COG3715@2|Bacteria,1RHFJ@1224|Proteobacteria,42SZF@68525|delta/epsilon subdivisions,2WPSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PTS system	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
GDHHQS2_k127_1017677_14	861299.J421_3125	7.772e-97	336.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
GDHHQS2_k127_1017677_26	1379270.AUXF01000005_gene735	7.961e-26	117.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS2_k127_1017677_1	861299.J421_3127	1.903e-253	795.0	COG1080@1|root,COG1080@2|Bacteria,1ZT3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS2_k127_1017677_6	379066.GAU_1484	6.539e-183	581.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS2_k127_1043599_0	861299.J421_5976	3.217e-113	376.0	COG1533@1|root,COG1533@2|Bacteria,1ZUFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_1043599_3	861299.J421_4381	1.602e-35	139.0	COG2154@1|root,COG2154@2|Bacteria,1ZU5C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS2_k127_1043599_1	861299.J421_4380	1.157e-80	277.0	COG0670@1|root,COG0670@2|Bacteria	2|Bacteria	M	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
GDHHQS2_k127_1043599_2	379066.GAU_2722	6.718e-57	205.0	COG0546@1|root,COG0546@2|Bacteria,1ZU5R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FJ	Haloacid dehalogenase-like hydrolase	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS2_k127_1043599_4	1396141.BATP01000044_gene1490	1.536e-21	96.0	COG0274@1|root,COG0274@2|Bacteria,46SXF@74201|Verrucomicrobia,2IUM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	DeoC/LacD family aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DeoC
GDHHQS2_k127_1044230_11	765912.Thimo_3089	0.0001067	54.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX1E@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
GDHHQS2_k127_1044230_3	266117.Rxyl_1072	2.938e-92	319.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_1044230_4	861299.J421_3988	3.841e-86	302.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_1044230_2	1379698.RBG1_1C00001G1210	1.926e-133	440.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_1044230_10	1379270.AUXF01000002_gene1199	2.028e-17	88.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_1044230_9	861299.J421_6361	1.662e-24	115.0	2F5SD@1|root,33YB8@2|Bacteria,1ZUXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1044230_1	1379270.AUXF01000003_gene3394	1.925e-140	454.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS2_k127_1044230_5	1379270.AUXF01000003_gene3395	6.09e-49	184.0	COG3166@1|root,COG3166@2|Bacteria,1ZTR8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
GDHHQS2_k127_1044230_7	1379270.AUXF01000003_gene3396	2.263e-44	168.0	COG3167@1|root,COG3167@2|Bacteria,1ZTZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GDHHQS2_k127_1044230_8	1379270.AUXF01000003_gene3397	3.119e-37	150.0	2F6AC@1|root,33YU1@2|Bacteria,1ZTY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1044230_0	861299.J421_3976	1.104e-198	642.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
GDHHQS2_k127_1044230_6	861299.J421_3975	1.261e-47	183.0	COG3391@1|root,COG3391@2|Bacteria,1ZT90@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1048090_7	443144.GM21_2504	1.045e-42	158.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS2_k127_1048090_4	525903.Taci_0092	5.358e-83	286.0	COG1117@1|root,COG1117@2|Bacteria,3TA2P@508458|Synergistetes	508458|Synergistetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS2_k127_1048090_2	1131812.JQMS01000001_gene1241	9.478e-106	350.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia,2NSSM@237|Flavobacterium	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS2_k127_1048090_6	379066.GAU_2370	7.281e-71	250.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS2_k127_1048090_1	379066.GAU_2373	2.748e-146	470.0	COG0306@1|root,COG0306@2|Bacteria,1ZSZ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS2_k127_1048090_5	861299.J421_3846	9.8e-73	250.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS2_k127_1048090_3	215803.DB30_3898	1.41e-105	347.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_1048090_0	1379270.AUXF01000003_gene3556	1.01e-158	502.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS2_k127_106029_8	107635.AZUO01000001_gene431	2.767e-08	64.0	2DDTS@1|root,2ZJ8M@2|Bacteria,1NJS6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_106029_5	118168.MC7420_1914	5.735e-17	96.0	2DRBA@1|root,33B2N@2|Bacteria,1GAYX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_106029_4	1185652.USDA257_c53240	2.599e-21	110.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,4B8S4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GlcNAc transferase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
GDHHQS2_k127_106029_6	269799.Gmet_0284	1.213e-15	91.0	COG4319@1|root,COG4319@2|Bacteria,1P8UQ@1224|Proteobacteria,43384@68525|delta/epsilon subdivisions,2WY2X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_106029_7	547045.NEISICOT_02160	4.461e-14	86.0	29355@1|root,2ZQN9@2|Bacteria,1RFN1@1224|Proteobacteria,2VSAG@28216|Betaproteobacteria,2KR84@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_106029_0	379066.GAU_1229	4.6e-210	663.0	COG1028@1|root,COG1028@2|Bacteria,1ZT0F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS2_k127_106029_1	383372.Rcas_4129	7.181e-51	194.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_106029_3	1380386.JIAW01000026_gene6900	6.442e-25	110.0	29XQK@1|root,30JGA@2|Bacteria,2IGVS@201174|Actinobacteria,2390P@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_106029_2	118173.KB235914_gene817	9.414e-40	149.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1HGKE@1150|Oscillatoriales	1117|Cyanobacteria	O	Ribosomal RNA adenine dimethylase	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_1066437_0	861299.J421_1729	1.054e-190	622.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_1066437_1	882082.SaccyDRAFT_2363	5.035e-09	63.0	COG0662@1|root,COG0662@2|Bacteria,2IKY8@201174|Actinobacteria,4EC0T@85010|Pseudonocardiales	201174|Actinobacteria	G	domain-containing protein	sppH	-	-	ko:K14673	-	-	-	-	ko00000,ko01008	-	-	-	Cupin_2
GDHHQS2_k127_107797_4	595537.Varpa_3379	5.709e-16	85.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,4AAJQ@80864|Comamonadaceae	28216|Betaproteobacteria	H	TonB-dependent receptor plug	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_107797_0	760192.Halhy_1130	0.0	1270.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1IRCI@117747|Sphingobacteriia	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
GDHHQS2_k127_107797_2	379066.GAU_3906	3.391e-68	253.0	COG3055@1|root,COG3055@2|Bacteria,1ZUV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
GDHHQS2_k127_107797_1	861299.J421_1344	1.222e-101	333.0	COG0262@1|root,COG0262@2|Bacteria,1ZVA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_107797_3	404380.Gbem_1222	3.118e-53	195.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,42QQX@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
GDHHQS2_k127_107797_5	1297742.A176_04703	2.551e-12	73.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1095105_8	1109445.AGSX01000039_gene212	1.074e-09	62.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1Z0XJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	Nitric oxide reductase activation protein	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
GDHHQS2_k127_1095105_2	861299.J421_4384	5.96e-129	417.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
GDHHQS2_k127_1095105_0	323848.Nmul_A1255	2.436e-232	725.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,371TN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c oxidase, subunit I	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
GDHHQS2_k127_1095105_3	323848.Nmul_A1256	1.985e-115	377.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,2VQ50@28216|Betaproteobacteria,37328@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c	norC	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
GDHHQS2_k127_1095105_1	861299.J421_6137	7.536e-138	445.0	COG1171@1|root,COG1171@2|Bacteria,1ZU14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_1095105_6	1379270.AUXF01000001_gene2285	1.251e-89	301.0	COG3819@1|root,COG3819@2|Bacteria,1ZUCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
GDHHQS2_k127_1095105_5	1379270.AUXF01000001_gene2286	5.004e-112	374.0	COG3817@1|root,COG3817@2|Bacteria,1ZU8S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
GDHHQS2_k127_1095105_4	1254432.SCE1572_37770	2.47e-113	388.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
GDHHQS2_k127_1095639_3	379066.GAU_2003	1.001e-41	156.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS2_k127_1095639_5	1458357.BG58_00350	1.286e-25	121.0	COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,2VRR2@28216|Betaproteobacteria,1K15T@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM ATPase, BadF BadG BcrA BcrD type	nagK	-	2.7.1.8	ko:K18676	ko00520,ko01100,map00520,map01100	-	R01961	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
GDHHQS2_k127_1095639_1	861299.J421_3611	2.637e-162	524.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
GDHHQS2_k127_1095639_0	379066.GAU_2006	8.148e-242	755.0	COG0531@1|root,COG0531@2|Bacteria,1ZT2B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_1095639_2	1267535.KB906767_gene2605	3.09e-159	506.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS2_k127_1095639_4	446466.Cfla_1513	2.22e-33	130.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4F0E3@85016|Cellulomonadaceae	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS2_k127_1099895_3	861299.J421_3011	5.089e-143	458.0	COG0148@1|root,COG0148@2|Bacteria,1ZTAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS2_k127_1099895_6	861299.J421_3010	7.797e-86	295.0	COG0204@1|root,COG0204@2|Bacteria,1ZT6D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS2_k127_1099895_7	861299.J421_3009	1.926e-82	287.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_1099895_5	861299.J421_3008	1.923e-114	392.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1ZTAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GDHHQS2_k127_1099895_8	861299.J421_3006	3.556e-55	197.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1099895_0	379066.GAU_1295	2.568e-197	623.0	COG0112@1|root,COG0112@2|Bacteria,1ZT5K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS2_k127_1099895_9	379066.GAU_1294	1.563e-52	189.0	COG0698@1|root,COG0698@2|Bacteria,1ZUTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS2_k127_1099895_2	861299.J421_3004	4.872e-160	511.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS2_k127_1099895_1	861299.J421_3003	7.821e-178	563.0	COG1960@1|root,COG1960@2|Bacteria,1ZSRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_1099895_4	1379270.AUXF01000005_gene596	1.146e-126	416.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_1099895_10	861299.J421_3001	5.581e-29	119.0	COG1266@1|root,COG1266@2|Bacteria,1ZTXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_1107897_0	1280694.AUJQ01000005_gene1378	1.192e-101	341.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3NGTN@46205|Pseudobutyrivibrio	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS2_k127_1107897_1	861299.J421_2893	7.797e-86	295.0	2F044@1|root,33T7T@2|Bacteria	861299.J421_2893|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1107897_2	1379270.AUXF01000003_gene3844	5.532e-10	72.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_1109464_0	861299.J421_4121	1.271e-98	327.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS2_k127_1109464_1	861299.J421_4120	6.9e-74	256.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS2_k127_1109464_2	861299.J421_2739	3.343e-68	240.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	-	3.2.2.27	ko:K03648,ko:K21929	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
GDHHQS2_k127_1109464_3	1408813.AYMG01000028_gene2501	4.346e-05	49.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1IPKY@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_113611_5	861299.J421_3355	2.424e-09	58.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS2_k127_113611_4	861299.J421_3353	1.264e-36	143.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS2_k127_113611_1	861299.J421_3350	9.668e-155	497.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS2_k127_113611_0	861299.J421_3349	8.133e-296	919.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS2_k127_113611_2	861299.J421_3348	4.087e-121	393.0	COG0500@1|root,COG2226@2|Bacteria,1ZTCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_113611_3	861299.J421_3347	4.425e-69	236.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS2_k127_116392_3	1170562.Cal6303_4120	2.629e-88	304.0	COG0457@1|root,COG0457@2|Bacteria,1GE9K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
GDHHQS2_k127_116392_0	452637.Oter_1429	3.399e-166	534.0	COG1222@1|root,COG4235@1|root,COG1222@2|Bacteria,COG4235@2|Bacteria,46Z7P@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS2_k127_116392_2	492774.JQMB01000011_gene4527	3.102e-149	476.0	COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,2TRGD@28211|Alphaproteobacteria,4BBTW@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF817
GDHHQS2_k127_116392_1	1082933.MEA186_27600	3.374e-153	489.0	COG4271@1|root,COG4271@2|Bacteria,1R4Z7@1224|Proteobacteria	1224|Proteobacteria	K	nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like,cNMP_binding
GDHHQS2_k127_116392_4	861299.J421_3829	1.37e-17	82.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
GDHHQS2_k127_1176131_2	861299.J421_6306	1.071e-09	61.0	COG1734@1|root,COG1734@2|Bacteria,1ZV6D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1176131_1	2002.JOEQ01000022_gene6872	2.017e-25	106.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4EGQW@85012|Streptosporangiales	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_1176131_0	1163617.SCD_n00704	0.0	1071.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
GDHHQS2_k127_119088_1	861299.J421_0110	4.134e-107	361.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_119088_0	1089550.ATTH01000001_gene363	2.545e-146	488.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1FJXK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_120390_1	861299.J421_2909	2.375e-97	323.0	COG1012@1|root,COG1012@2|Bacteria,1ZUBM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_120390_0	861299.J421_3729	7.872e-220	695.0	COG0591@1|root,COG0591@2|Bacteria,1ZUAP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
GDHHQS2_k127_120390_3	861299.J421_3730	1.608e-34	138.0	2CFMM@1|root,347ZP@2|Bacteria,1ZV4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_120390_2	1379270.AUXF01000001_gene2287	1.447e-41	154.0	2C57D@1|root,2Z7RS@2|Bacteria,1ZUNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
GDHHQS2_k127_128344_1	861299.J421_1774	2.934e-74	255.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	2|Bacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_128344_0	379066.GAU_0050	2.086e-159	527.0	2C9ZY@1|root,33R5C@2|Bacteria,1ZSVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_128344_2	1278073.MYSTI_07565	2.372e-39	151.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria,2YW9J@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_4
GDHHQS2_k127_1283812_5	861299.J421_3553	4.942e-29	117.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_1283812_2	861299.J421_3552	3.109e-54	199.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
GDHHQS2_k127_1283812_0	861299.J421_3551	2.915e-118	394.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_1283812_4	379066.GAU_1940	4.504e-38	153.0	COG1729@1|root,COG1729@2|Bacteria,1ZTU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
GDHHQS2_k127_1283812_1	861299.J421_3548	1.117e-91	308.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS2_k127_1283812_3	379066.GAU_1938	1.091e-48	183.0	COG1452@1|root,COG1452@2|Bacteria,1ZT14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1313060_0	404380.Gbem_1024	1.588e-95	342.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS2_k127_1313060_1	861299.J421_4180	2.527e-62	224.0	COG1836@1|root,COG1836@2|Bacteria,1ZTT3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS2_k127_1394901_11	861299.J421_3366	1.27e-97	322.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_1394901_7	861299.J421_3367	3.342e-124	407.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS2_k127_1394901_14	1379270.AUXF01000006_gene162	2.824e-51	193.0	COG3605@1|root,COG3605@2|Bacteria,1ZT8P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
GDHHQS2_k127_1394901_8	861299.J421_3369	3.594e-110	361.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS2_k127_1394901_15	861299.J421_3370	2.796e-49	183.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023	2.2.1.2	ko:K00616,ko:K08313,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501	TAL_FSA
GDHHQS2_k127_1394901_4	379066.GAU_1730	4.197e-160	517.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_1394901_3	379066.GAU_1731	1.128e-216	686.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS2_k127_1394901_5	861299.J421_3374	1.38e-128	422.0	COG0152@1|root,COG0152@2|Bacteria,1ZT6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS2_k127_1394901_12	861299.J421_3375	1.581e-84	286.0	COG0688@1|root,COG0688@2|Bacteria,1ZU9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS2_k127_1394901_10	379066.GAU_1734	1.064e-103	346.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_1394901_17	1379270.AUXF01000006_gene155	7.319e-28	115.0	COG1828@1|root,COG1828@2|Bacteria,1ZU3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
GDHHQS2_k127_1394901_9	861299.J421_3378	2.437e-106	349.0	COG0047@1|root,COG0047@2|Bacteria,1ZTF8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GDHHQS2_k127_1394901_1	861299.J421_3380	0.0	1158.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_1394901_2	861299.J421_3381	1.699e-227	717.0	COG0034@1|root,COG0034@2|Bacteria,1ZTD7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6
GDHHQS2_k127_1394901_0	861299.J421_3382	0.0	1344.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS2_k127_1394901_13	290397.Adeh_2418	4.115e-83	290.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1394901_16	1122947.FR7_1481	3.029e-44	169.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
GDHHQS2_k127_1394901_21	693444.D782_3056	1.448e-05	57.0	COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,1RS5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	ybhN	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_1394901_6	278963.ATWD01000001_gene2473	2.322e-126	417.0	COG4232@1|root,COG4232@2|Bacteria,3Y771@57723|Acidobacteria	57723|Acidobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Thioredoxin_7
GDHHQS2_k127_1394901_19	379066.GAU_3166	5.821e-23	104.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS2_k127_1394901_18	2880.D7G6W2	9.25e-28	131.0	COG0457@1|root,KOG4658@1|root,KOG1840@2759|Eukaryota,KOG4658@2759|Eukaryota	2759|Eukaryota	S	ADP binding	-	-	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_16,TPR_4,TPR_7,TPR_8
GDHHQS2_k127_1394901_20	375286.mma_2474	2.327e-10	73.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria,475YZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular repeat, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
GDHHQS2_k127_1398684_4	1123037.AUDE01000001_gene1732	2.034e-06	58.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia	976|Bacteroidetes	M	Lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GDHHQS2_k127_1398684_3	861299.J421_1004	9.276e-19	95.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GDHHQS2_k127_1398684_2	861299.J421_2180	2.248e-19	98.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GDHHQS2_k127_1398684_1	379066.GAU_1905	4.877e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,1ZUKF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_1398684_0	1183438.GKIL_3719	1.63e-200	637.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GDHHQS2_k127_1400661_0	861299.J421_6243	1.059e-194	621.0	COG4888@1|root,COG4888@2|Bacteria,1ZURG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_1400661_2	861299.J421_1631	1.984e-24	107.0	COG4095@1|root,COG4095@2|Bacteria	2|Bacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
GDHHQS2_k127_1400661_1	234267.Acid_4350	4.747e-47	172.0	COG0560@1|root,COG0560@2|Bacteria,3Y6IV@57723|Acidobacteria	57723|Acidobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS2_k127_1412033_5	1379270.AUXF01000006_gene143	4.31e-59	209.0	COG0622@1|root,COG0622@2|Bacteria,1ZTPR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
GDHHQS2_k127_1412033_3	379066.GAU_1752	4.525e-136	454.0	COG0019@1|root,COG0019@2|Bacteria,1ZT6G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS2_k127_1412033_0	861299.J421_3390	9.235e-250	779.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GDHHQS2_k127_1412033_1	861299.J421_3391	2.166e-160	515.0	COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
GDHHQS2_k127_1412033_4	861299.J421_3392	1.961e-129	434.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
GDHHQS2_k127_1412033_2	379066.GAU_1756	1.394e-145	465.0	COG0777@1|root,COG0777@2|Bacteria,1ZSSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_1428518_7	1379270.AUXF01000002_gene1468	3.656e-71	244.0	COG0789@1|root,COG0789@2|Bacteria,1ZTHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_1428518_0	861299.J421_1403	0.0	1780.0	COG1201@1|root,COG1201@2|Bacteria,1ZTN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS2_k127_1428518_2	861299.J421_0459	1.333e-154	499.0	COG1502@1|root,COG1502@2|Bacteria,1ZTU6@142182|Gemmatimonadetes	2|Bacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GDHHQS2_k127_1428518_4	379066.GAU_0172	3.426e-122	397.0	COG5534@1|root,COG5534@2|Bacteria,1ZTEX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RPA
GDHHQS2_k127_1428518_1	861299.J421_0464	6.802e-194	619.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS2_k127_1428518_3	861299.J421_0472	3.427e-150	483.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_1428518_6	861299.J421_0497	2.149e-85	289.0	2EVAX@1|root,33NRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1428518_8	861299.J421_0499	4.139e-31	122.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_1428518_5	861299.J421_0599	1.322e-118	389.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS2_k127_1434976_1	861299.J421_3595	9.344e-135	438.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_1434976_7	379066.GAU_1992	4.857e-08	57.0	2AF2V@1|root,3151C@2|Bacteria,1ZVA0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1434976_6	1379270.AUXF01000003_gene3865	6.894e-27	117.0	2FHQX@1|root,349IG@2|Bacteria,1ZU2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1434976_2	861299.J421_3592	2.568e-97	325.0	COG0613@1|root,COG0613@2|Bacteria,1ZTHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GDHHQS2_k127_1434976_3	861299.J421_3591	3.663e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_1434976_4	1118054.CAGW01000046_gene1548	1.171e-83	289.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26QN5@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_1434976_5	861299.J421_3589	1.74e-78	275.0	COG0491@1|root,COG0491@2|Bacteria,1ZTMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_1434976_0	861299.J421_3587	1.704e-219	689.0	COG1027@1|root,COG1027@2|Bacteria,1ZSUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS2_k127_146537_0	1121123.AUAO01000003_gene2364	1.032e-189	611.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2KI6R@204458|Caulobacterales	204458|Caulobacterales	E	leukotriene A-4 hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS2_k127_146537_1	543728.Vapar_4999	1.791e-41	157.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_1471010_0	401053.AciPR4_0184	4.359e-54	192.0	COG0006@1|root,COG0006@2|Bacteria,3Y460@57723|Acidobacteria,2JI89@204432|Acidobacteriia	204432|Acidobacteriia	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_1471010_1	1500897.JQNA01000002_gene471	9.116e-45	178.0	COG2718@1|root,COG2718@2|Bacteria,1MVXE@1224|Proteobacteria,2VYMH@28216|Betaproteobacteria,1K5H8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
GDHHQS2_k127_1471010_4	1282876.BAOK01000002_gene822	1.412e-06	61.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,4BQBT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS2_k127_1471010_3	1380394.JADL01000008_gene3516	1.68e-09	59.0	COG0151@1|root,COG0151@2|Bacteria,1NEZN@1224|Proteobacteria,2UP1I@28211|Alphaproteobacteria,2JVQF@204441|Rhodospirillales	204441|Rhodospirillales	F	Phosphoribosylglycinamide synthetase, C domain	-	-	-	-	-	-	-	-	-	-	-	-	GARS_A
GDHHQS2_k127_1628115_1	365046.Rta_06020	9.019e-112	369.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1628115_6	1458427.BAWN01000012_gene707	2.154e-16	91.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,2VU9J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_1628115_0	349163.Acry_2829	3.735e-134	436.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2JRG6@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1628115_4	317936.Nos7107_2777	6.164e-60	216.0	COG3485@1|root,COG3485@2|Bacteria,1G538@1117|Cyanobacteria,1HQQI@1161|Nostocales	1117|Cyanobacteria	Q	COGs COG3485 Protocatechuate 3 4-dioxygenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
GDHHQS2_k127_1628115_5	309801.trd_A0609	4.949e-43	166.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_1628115_3	861299.J421_0377	1.518e-69	243.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.45,4.1.2.14,4.1.3.42	ko:K00874,ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R01541,R05605	RC00002,RC00017,RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS2_k127_1628115_2	1340493.JNIF01000003_gene1738	8.184e-73	253.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_1744535_0	861299.J421_3249	2.715e-127	413.0	COG0463@1|root,COG0463@2|Bacteria,1ZTEI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_1744535_1	861299.J421_3248	7.499e-111	371.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1744535_2	379066.GAU_1614	4.461e-50	192.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_181892_3	97139.C824_01933	0.0005941	48.0	COG1879@1|root,COG1879@2|Bacteria,1V607@1239|Firmicutes,24G4K@186801|Clostridia,36S34@31979|Clostridiaceae	186801|Clostridia	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_181892_1	1122214.AQWH01000005_gene1277	2.311e-36	150.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS2_k127_181892_0	439235.Dalk_3400	3.932e-86	310.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WMP9@28221|Deltaproteobacteria,2MPMH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GDHHQS2_k127_181892_2	1297742.A176_04659	2.459e-08	60.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_1837060_2	1379270.AUXF01000002_gene1820	4.43e-111	369.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_1837060_4	671143.DAMO_1287	2.129e-94	323.0	COG2801@1|root,COG2801@2|Bacteria,2NQ4I@2323|unclassified Bacteria	2|Bacteria	L	Homeodomain-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
GDHHQS2_k127_1837060_6	861299.J421_2399	7.436e-61	214.0	COG1832@1|root,COG1832@2|Bacteria,1ZTUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS2_k127_1837060_0	861299.J421_2400	1.574e-171	546.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
GDHHQS2_k127_1837060_8	909663.KI867150_gene1783	4.991e-46	177.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MQFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Lysin motif	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GDHHQS2_k127_1837060_9	1144275.COCOR_01613	2.071e-37	146.0	2CNQU@1|root,32SHJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
GDHHQS2_k127_1837060_7	1419583.V466_11210	3.059e-59	213.0	COG2173@1|root,COG3786@1|root,COG2173@2|Bacteria,COG3786@2|Bacteria,1RENK@1224|Proteobacteria,1S3SJ@1236|Gammaproteobacteria,1YR3J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GDHHQS2_k127_1837060_1	379066.GAU_0513	9.676e-161	541.0	COG2027@1|root,COG2027@2|Bacteria,1ZT1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS2_k127_1837060_10	861299.J421_2404	3.949e-34	139.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1837060_3	1379270.AUXF01000002_gene1829	1.757e-105	349.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GDHHQS2_k127_1837060_11	379066.GAU_0507	1.964e-31	126.0	2EKS3@1|root,33EFV@2|Bacteria,1ZTY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GDHHQS2_k127_1837060_5	379066.GAU_0506	2.161e-73	248.0	COG1845@1|root,COG1845@2|Bacteria,1ZT8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS2_k127_1863996_1	251221.35210834	2.256e-164	523.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_1863996_2	379066.GAU_2767	3.025e-20	96.0	2DWK2@1|root,340S5@2|Bacteria,1ZTSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1863996_0	861299.J421_4433	3.68e-317	980.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1868135_0	1267534.KB906759_gene1822	3.779e-105	362.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	mmpL3	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264	-	ko:K06994,ko:K07003,ko:K20466,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.5,2.A.6.5.6	-	-	MMPL
GDHHQS2_k127_1868135_3	1124991.MU9_2789	2.43e-16	94.0	2BZ6D@1|root,2ZC6J@2|Bacteria,1RBC8@1224|Proteobacteria,1S3G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1868135_1	1123252.ATZF01000003_gene3596	2.298e-40	166.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
GDHHQS2_k127_1868135_4	118163.Ple7327_1235	3.456e-08	64.0	COG2833@1|root,COG2833@2|Bacteria,1GQKS@1117|Cyanobacteria,3VIR2@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
GDHHQS2_k127_1868135_5	420662.Mpe_B0247	2.103e-05	55.0	COG1633@1|root,COG1633@2|Bacteria,1MXX8@1224|Proteobacteria,2VI3H@28216|Betaproteobacteria,1KJG3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1868135_2	575540.Isop_0332	2.846e-27	117.0	COG0172@1|root,COG0172@2|Bacteria,2J3SB@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1871957_4	861299.J421_3355	2.18e-142	459.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS2_k127_1871957_0	861299.J421_3356	1.493e-238	764.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_1871957_2	861299.J421_3358	8.196e-155	496.0	COG0820@1|root,COG0820@2|Bacteria,1ZTAJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
GDHHQS2_k127_1871957_10	861299.J421_3360	5.464e-70	241.0	COG0801@1|root,COG1713@1|root,COG0801@2|Bacteria,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS2_k127_1871957_9	1120960.ATXG01000011_gene3550	1.335e-72	256.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4FN3G@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS2_k127_1871957_6	313612.L8106_07696	5.144e-81	278.0	COG0413@1|root,COG0413@2|Bacteria,1G0SC@1117|Cyanobacteria,1H9II@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GDHHQS2_k127_1871957_11	1123300.AUIN01000009_gene303	1.79e-28	124.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GDHHQS2_k127_1871957_13	861299.J421_3361	1.227e-22	101.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB2	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
GDHHQS2_k127_1871957_7	1379270.AUXF01000006_gene170	1.725e-79	276.0	COG0159@1|root,COG0159@2|Bacteria,1ZSYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS2_k127_1871957_3	379066.GAU_1721	8.717e-145	477.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_1871957_5	1379270.AUXF01000006_gene168	4.854e-122	411.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_1871957_1	379066.GAU_1723	2.617e-196	618.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_1871957_12	637390.AFOH01000130_gene1959	2.499e-25	113.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,2NCVN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS2_k127_1871957_8	1379270.AUXF01000006_gene165	1.739e-73	257.0	COG0134@1|root,COG0134@2|Bacteria,1ZTMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS2_k127_189649_2	1075090.GOAMR_62_00460	5.271e-41	152.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4GCHV@85026|Gordoniaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaC	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_189649_0	861299.J421_5582	7.992e-117	382.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS2_k127_189649_1	517418.Ctha_2620	4.458e-56	200.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_1908625_5	1028800.RG540_PA05150	1.079e-08	58.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,4BETQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS2_k127_1908625_0	861299.J421_0488	2.111e-155	500.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_1908625_4	243231.GSU0698	5.781e-18	99.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_1908625_1	338963.Pcar_1179	9.046e-41	167.0	COG2206@1|root,COG2206@2|Bacteria,1RE2G@1224|Proteobacteria,42S6Z@68525|delta/epsilon subdivisions,2WNCP@28221|Deltaproteobacteria,43TC7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cyclic diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_1908625_3	379066.GAU_2523	2.171e-18	89.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_1908625_2	861299.J421_0291	1.772e-27	119.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS2_k127_1929729_1	1123508.JH636440_gene2636	6.36e-12	66.0	COG0467@1|root,COG0467@2|Bacteria,2IZBF@203682|Planctomycetes	203682|Planctomycetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS2_k127_1929729_2	483216.BACEGG_02343	9.884e-06	51.0	2DEHV@1|root,2ZN22@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1929729_0	1504672.669782768	8.566e-147	468.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
GDHHQS2_k127_1929909_1	1254432.SCE1572_02795	6.846e-88	299.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_1929909_2	861299.J421_6276	3.444e-71	263.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_6276|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1929909_4	911239.CF149_02229	1.302e-36	158.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_1929909_3	861299.J421_6162	1.117e-51	185.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_1929909_0	861299.J421_6163	3.321e-244	774.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_1935281_3	1267535.KB906767_gene3676	5.457e-44	169.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_1935281_1	861299.J421_5954	1.313e-103	342.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	-	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS2_k127_1935281_2	861299.J421_1380	7.505e-49	187.0	COG3142@1|root,COG3142@2|Bacteria,1ZTRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
GDHHQS2_k127_1935281_0	204669.Acid345_2325	5.46e-193	608.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_1942667_3	237727.NAP1_11743	1.655e-26	111.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,2KD9Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
GDHHQS2_k127_1942667_1	204669.Acid345_4011	1.447e-36	145.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1942667_2	1379270.AUXF01000002_gene1393	3.298e-29	124.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS2_k127_1942667_0	279714.FuraDRAFT_0324	8.833e-44	163.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KQ3F@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
GDHHQS2_k127_1943466_1	700598.Niako_1910	9.711e-12	65.0	COG0620@1|root,COG0620@2|Bacteria,4NJAH@976|Bacteroidetes,1IZXY@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0620 Methionine synthase II (cobalamin-independent)	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS2_k127_1943466_0	861299.J421_6016	6.043e-246	782.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1963713_1	861299.J421_1510	8.081e-161	516.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS2_k127_1963713_3	861299.J421_2323	5.019e-113	373.0	COG0157@1|root,COG0157@2|Bacteria,1ZSR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GDHHQS2_k127_1963713_0	1379270.AUXF01000002_gene1768	1.48e-162	517.0	COG0379@1|root,COG0379@2|Bacteria,1ZT10@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS2_k127_1963713_2	861299.J421_2321	2.151e-153	489.0	COG0029@1|root,COG0029@2|Bacteria,1ZT8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_1967677_3	861299.J421_4207	3.529e-137	442.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_1967677_5	861299.J421_4209	7.681e-98	329.0	COG1131@1|root,COG1131@2|Bacteria,1ZV6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
GDHHQS2_k127_1967677_6	861299.J421_4210	1.759e-53	205.0	COG0457@1|root,COG0457@2|Bacteria,1ZTZG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1967677_2	861299.J421_4211	1.218e-156	501.0	COG0457@1|root,COG0457@2|Bacteria,1ZSYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
GDHHQS2_k127_1967677_1	861299.J421_4222	3.831e-160	515.0	COG3844@1|root,COG3844@2|Bacteria,1ZTZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_1967677_4	861299.J421_4225	3.932e-122	403.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
GDHHQS2_k127_1967677_0	379066.GAU_2620	1.206e-314	976.0	COG1048@1|root,COG1048@2|Bacteria,1ZTE7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS2_k127_1973828_3	861299.J421_3834	9.151e-76	262.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_1973828_0	234267.Acid_4011	7.454e-112	376.0	COG3503@1|root,COG3503@2|Bacteria,3Y3XK@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS2_k127_1973828_2	204669.Acid345_4600	2.346e-86	303.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_1973828_5	861299.J421_3696	6.084e-31	124.0	COG0361@1|root,COG0361@2|Bacteria,1ZV5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS2_k127_1973828_4	861299.J421_1300	1.855e-36	139.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_1973828_1	497965.Cyan7822_1022	3.187e-97	328.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,3KHGC@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GDHHQS2_k127_1973828_7	379066.GAU_2612	3.48e-06	53.0	2AUA7@1|root,31JXQ@2|Bacteria,1ZV7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1973828_6	153721.MYP_3457	8.052e-27	116.0	COG2217@1|root,COG2217@2|Bacteria,4PKPG@976|Bacteroidetes,47XY3@768503|Cytophagia	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1978921_5	404380.Gbem_0063	1.486e-37	148.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43T46@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789,ko:K18138	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_1978921_4	1379270.AUXF01000002_gene1841	2.938e-82	287.0	COG0845@1|root,COG0845@2|Bacteria,1ZTJD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_1978921_3	861299.J421_6127	6.164e-93	324.0	COG1309@1|root,COG1538@1|root,COG1309@2|Bacteria,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	ttgC	-	-	-	-	-	-	-	-	-	-	-	OEP,TetR_N
GDHHQS2_k127_1978921_0	861299.J421_3325	3.343e-193	617.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
GDHHQS2_k127_1978921_1	1379270.AUXF01000006_gene199	2.287e-175	562.0	COG0260@1|root,COG0260@2|Bacteria,1ZSPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS2_k127_1978921_2	861299.J421_3323	4.819e-102	359.0	COG4206@1|root,COG4206@2|Bacteria,1ZT1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
GDHHQS2_k127_2006259_4	743719.PaelaDRAFT_1340	4.035e-22	102.0	2BWG6@1|root,32WUM@2|Bacteria,1VBBF@1239|Firmicutes,4HNFJ@91061|Bacilli,26UFI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2006259_3	379066.GAU_0541	3.881e-32	128.0	COG0730@1|root,COG0730@2|Bacteria,1ZU67@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_2006259_0	861299.J421_0094	3.305e-199	629.0	COG0520@1|root,COG0520@2|Bacteria,1ZT1P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_2006259_1	926549.KI421517_gene113	2.699e-112	376.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,47MHW@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2006259_5	1242864.D187_007276	8.291e-06	56.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_2021250_3	1379270.AUXF01000002_gene1566	7.057e-86	297.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1566|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_2021250_2	861299.J421_2698	1.187e-112	374.0	COG0454@1|root,COG0454@2|Bacteria,1ZSVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_2021250_0	861299.J421_2697	1.193e-251	807.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS2_k127_2021250_1	861299.J421_2696	7.206e-122	398.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GDHHQS2_k127_2037124_8	1379270.AUXF01000006_gene129	9.483e-36	138.0	COG0184@1|root,COG0184@2|Bacteria,1ZU0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS2_k127_2037124_0	379066.GAU_1764	0.0	1086.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS2_k127_2037124_5	861299.J421_3400	4.585e-163	523.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_2037124_3	861299.J421_3399	4.316e-192	604.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS2_k127_2037124_2	861299.J421_3398	8.695e-202	631.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS2_k127_2037124_6	379066.GAU_1760	1.912e-73	261.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS2_k127_2037124_7	861299.J421_3396	1.415e-54	199.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
GDHHQS2_k127_2037124_1	861299.J421_3395	5.31e-220	702.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS2_k127_2037124_4	379066.GAU_1757	3.411e-168	541.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_2039081_3	1267534.KB906759_gene1703	5.509e-45	176.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2039081_7	653733.Selin_1026	1.309e-05	57.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
GDHHQS2_k127_2039081_2	1121904.ARBP01000004_gene934	7.866e-46	183.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NEX2@976|Bacteroidetes,47NV4@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_2039081_0	404589.Anae109_3731	8.49e-151	510.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
GDHHQS2_k127_2039081_1	861299.J421_2546	5.986e-80	277.0	COG1597@1|root,COG1597@2|Bacteria,1ZU66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
GDHHQS2_k127_2039081_4	880072.Desac_0492	1.896e-41	158.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
GDHHQS2_k127_204346_0	861299.J421_1067	2.779e-127	420.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS2_k127_204346_1	861299.J421_1065	7.997e-69	243.0	COG2220@1|root,COG2220@2|Bacteria	861299.J421_1065|-	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2051250_1	1144932.ATTF01000022_gene31	3.923e-06	56.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,4BQC5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_2051250_0	861299.J421_0916	2.602e-160	509.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_2072797_0	1379270.AUXF01000004_gene3319	1.384e-124	408.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_2072797_2	631454.N177_0576	4.135e-28	117.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JNMS@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	cckA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_2072797_1	861299.J421_3625	1.387e-54	197.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
GDHHQS2_k127_2072797_3	56780.SYN_01761	3.205e-06	56.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02246,ko:K08084	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.15.2	-	-	GspH,N_methyl
GDHHQS2_k127_2086961_2	1089547.KB913013_gene3982	4.655e-102	352.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,47MSB@768503|Cytophagia	976|Bacteroidetes	S	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase,SGL
GDHHQS2_k127_2086961_4	629773.AORY01000002_gene1718	5.504e-52	189.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2TW76@28211|Alphaproteobacteria,2K4MG@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_2086961_3	861299.J421_4501	2.327e-59	220.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4501|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2086961_1	379066.GAU_3908	4.472e-118	407.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS2_k127_2086961_6	1038867.AXAY01000001_gene6544	6.735e-05	46.0	2EIK5@1|root,33CBF@2|Bacteria,1N844@1224|Proteobacteria,2UFRU@28211|Alphaproteobacteria,3K17C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2086961_0	1379270.AUXF01000002_gene1477	1.422e-237	740.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS2_k127_2097490_0	580332.Slit_2523	1.085e-268	839.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
GDHHQS2_k127_2097490_1	861299.J421_6272	4.497e-237	760.0	28MSW@1|root,2ZB15@2|Bacteria,1ZUI9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2097490_3	2423.NA23_0202175	7.021e-83	293.0	COG1653@1|root,COG1653@2|Bacteria,2GC1I@200918|Thermotogae	200918|Thermotogae	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_2097490_2	580331.Thit_0425	6.815e-92	311.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
GDHHQS2_k127_2097490_4	390874.Tpet_0956	3.491e-48	192.0	COG0395@1|root,COG0395@2|Bacteria,2GCIV@200918|Thermotogae	200918|Thermotogae	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_2101321_13	1379270.AUXF01000003_gene3462	8.074e-08	62.0	COG3897@1|root,COG3897@2|Bacteria,1ZTUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2101321_2	861299.J421_3927	3.067e-108	369.0	COG0303@1|root,COG0303@2|Bacteria,1ZT4D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS2_k127_2101321_1	861299.J421_3926	2.869e-114	383.0	COG2027@1|root,COG2027@2|Bacteria,1ZSQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS2_k127_2101321_5	861299.J421_3925	5.659e-59	207.0	COG0720@1|root,COG0720@2|Bacteria,1ZTRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS2_k127_2101321_6	861299.J421_3923	2.152e-43	170.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2101321_0	861299.J421_3922	2.644e-234	734.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GDHHQS2_k127_2101321_11	379066.GAU_2457	1.4e-25	115.0	2A37A@1|root,30RNW@2|Bacteria,1ZUP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2101321_4	379066.GAU_2456	3.879e-85	290.0	COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS2_k127_2101321_3	861299.J421_3921	2.039e-87	301.0	COG3108@1|root,COG3108@2|Bacteria,1ZT3M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS2_k127_2101321_9	861299.J421_3920	3.145e-27	117.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2101321_7	861299.J421_3919	6.961e-42	161.0	COG3339@1|root,COG3339@2|Bacteria,1ZTZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS2_k127_2101321_10	1541065.JRFE01000009_gene4504	4.776e-26	109.0	COG1598@1|root,COG1598@2|Bacteria,1G97T@1117|Cyanobacteria,3VKM4@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_2101321_12	373994.Riv7116_2882	1.704e-25	106.0	COG1724@1|root,COG1724@2|Bacteria,1G7R9@1117|Cyanobacteria,1HQ4C@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_213781_4	1333998.M2A_2344	2.272e-97	323.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_213781_1	1379270.AUXF01000005_gene395	7.974e-161	514.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_213781_7	861299.J421_2889	8.035e-61	216.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS2_k127_213781_2	861299.J421_2888	4.284e-155	506.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS2_k127_213781_6	379066.GAU_1117	9.133e-79	269.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_213781_3	379066.GAU_1116	1.659e-121	394.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
GDHHQS2_k127_213781_8	379066.GAU_1115	1.401e-59	210.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GDHHQS2_k127_213781_10	1379270.AUXF01000005_gene388	4.762e-18	87.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_213781_5	861299.J421_2883	1.501e-88	295.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GDHHQS2_k127_213781_9	861299.J421_2882	1.618e-36	140.0	COG0718@1|root,COG0718@2|Bacteria,1ZU1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS2_k127_213781_0	861299.J421_2881	1.813e-169	546.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS2_k127_214868_5	1379270.AUXF01000002_gene1767	8.007e-103	338.0	COG0029@1|root,COG0029@2|Bacteria,1ZT8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_214868_0	861299.J421_2318	2.013e-154	507.0	COG1744@1|root,COG1744@2|Bacteria,1ZTAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS2_k127_214868_3	519441.Smon_0504	6.548e-143	471.0	COG3845@1|root,COG3845@2|Bacteria,378EE@32066|Fusobacteria	32066|Fusobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS2_k127_214868_1	861299.J421_2316	3.489e-152	489.0	COG4603@1|root,COG4603@2|Bacteria,1ZTDA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_214868_4	861299.J421_2315	2.185e-115	391.0	COG1079@1|root,COG1079@2|Bacteria,1ZTFZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_214868_2	861299.J421_2314	9.172e-144	466.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_214868_6	379066.GAU_2277	3.657e-05	46.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS2_k127_2185361_2	861299.J421_2523	5.777e-138	447.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
GDHHQS2_k127_2185361_5	861299.J421_2524	3.115e-83	289.0	COG0277@1|root,COG0277@2|Bacteria,1ZTRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
GDHHQS2_k127_2185361_0	861299.J421_2525	6.795e-205	648.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS2_k127_2185361_6	861299.J421_2345	9.864e-60	222.0	COG1597@1|root,COG1597@2|Bacteria,1ZVAI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS2_k127_2185361_1	379066.GAU_0602	1.226e-151	483.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_2185361_8	861299.J421_2531	6.047e-30	129.0	COG3584@1|root,COG3584@2|Bacteria	2|Bacteria	T	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3,SLH
GDHHQS2_k127_2185361_3	861299.J421_2532	3.724e-120	396.0	COG0337@1|root,COG0337@2|Bacteria,1ZSS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS2_k127_2185361_4	1379270.AUXF01000004_gene3280	1.851e-87	291.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS2_k127_2185361_9	1379270.AUXF01000003_gene3376	2.405e-22	100.0	2DING@1|root,303QG@2|Bacteria,1ZV8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
GDHHQS2_k127_2185361_7	861299.J421_0688	4.027e-56	202.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	rimL	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS2_k127_2185361_11	861299.J421_2537	9.888e-10	59.0	COG0492@1|root,COG0492@2|Bacteria,1ZSM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_2193518_2	379066.GAU_2027	1.117e-62	224.0	COG1802@1|root,COG1802@2|Bacteria,1ZUBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_2193518_0	713586.KB900536_gene2395	1.178e-137	445.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
GDHHQS2_k127_2193518_4	861299.J421_0718	8.106e-41	159.0	2F4AY@1|root,33X1J@2|Bacteria,1ZTWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2193518_3	221288.JH992901_gene2489	1.891e-53	196.0	COG1670@1|root,COG1670@2|Bacteria,1G621@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_2193518_1	240015.ACP_2729	2.372e-117	385.0	COG0031@1|root,COG0031@2|Bacteria,3Y45Z@57723|Acidobacteria,2JHUN@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2193518_5	1230457.C476_04023	1.973e-32	134.0	COG2020@1|root,arCOG03580@2157|Archaea,2XXQD@28890|Euryarchaeota,23W11@183963|Halobacteria	183963|Halobacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_225454_3	861299.J421_3904	1.345e-63	231.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
GDHHQS2_k127_225454_1	861299.J421_3905	1.303e-107	358.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS2_k127_225454_0	861299.J421_3906	4.095e-263	817.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GDHHQS2_k127_225454_2	861299.J421_3907	6.977e-102	336.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_2257320_1	1379270.AUXF01000005_gene585	5.799e-154	492.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS2_k127_2257320_0	861299.J421_2988	1.372e-318	991.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2370310_0	929556.Solca_3465	5.9e-61	213.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_2370310_1	861299.J421_4375	7.425e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2370310_3	1442599.JAAN01000015_gene3199	8.37e-10	64.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_2412873_2	861299.J421_5698	4.933e-62	218.0	COG2197@1|root,COG2197@2|Bacteria,1ZUCS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2412873_1	290397.Adeh_0511	4.721e-96	334.0	COG0475@1|root,COG0475@2|Bacteria,1RA3J@1224|Proteobacteria,43EWJ@68525|delta/epsilon subdivisions,2WTW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS2_k127_2412873_5	1123278.KB893574_gene6167	1.045e-09	67.0	2DP97@1|root,3313P@2|Bacteria,4PP9H@976|Bacteroidetes,47SB2@768503|Cytophagia	976|Bacteroidetes	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GDHHQS2_k127_2412873_0	404589.Anae109_0941	5.841e-103	347.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,2YVBA@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
GDHHQS2_k127_2412873_3	861299.J421_6117	1.531e-26	115.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS2_k127_2412873_4	1443665.JACA01000049_gene5417	4.579e-22	103.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1I3KX@117743|Flavobacteriia,2YJ63@290174|Aquimarina	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
GDHHQS2_k127_2433500_0	1382356.JQMP01000004_gene107	2.297e-68	247.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS2_k127_2433500_2	529709.PYCH_12070	8.951e-37	146.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_2433500_1	204669.Acid345_3835	4.648e-57	213.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria,2JMCG@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_2435223_4	861299.J421_2402	1.708e-152	492.0	COG4299@1|root,COG4299@2|Bacteria,1ZT4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
GDHHQS2_k127_2435223_1	861299.J421_3607	1.726e-258	811.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
GDHHQS2_k127_2435223_3	1045855.DSC_13360	5.406e-182	583.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RRY3@1236|Gammaproteobacteria,1XBYN@135614|Xanthomonadales	135614|Xanthomonadales	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_2435223_6	861299.J421_6332	2.58e-135	443.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS2_k127_2435223_5	861299.J421_3604	9.205e-139	462.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS2_k127_2435223_0	468059.AUHA01000002_gene533	0.0	1368.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IPAN@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS2_k127_2435223_2	468059.AUHA01000002_gene532	3.528e-250	785.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,1IP72@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
GDHHQS2_k127_2435223_7	468059.AUHA01000002_gene531	1.129e-57	210.0	29Z06@1|root,30KX7@2|Bacteria,4NZNI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS2_k127_2436785_5	314230.DSM3645_17275	1.097e-36	142.0	COG2764@1|root,COG2764@2|Bacteria,2J060@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
GDHHQS2_k127_2436785_3	1379270.AUXF01000002_gene1586	2.973e-101	364.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1586|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2436785_4	502025.Hoch_1576	1.379e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_2436785_0	861299.J421_0619	1.879e-201	637.0	COG1858@1|root,COG1858@2|Bacteria,1ZV0F@142182|Gemmatimonadetes	2|Bacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
GDHHQS2_k127_2436785_2	1237149.C900_04278	2.454e-113	378.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,47KSC@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
GDHHQS2_k127_2436785_1	861299.J421_0783	3.304e-170	545.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS2_k127_2439565_21	56107.Cylst_2352	2.165e-40	152.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1G0WY@1117|Cyanobacteria,1HMIN@1161|Nostocales	1117|Cyanobacteria	CE	Glycine D-amino acid oxidase (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
GDHHQS2_k127_2439565_17	379066.GAU_1134	1.058e-55	202.0	COG1878@1|root,COG1878@2|Bacteria,1ZU2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS2_k127_2439565_0	861299.J421_1532	5.062e-318	988.0	COG0021@1|root,COG0021@2|Bacteria,1ZTA2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GDHHQS2_k127_2439565_13	266117.Rxyl_1054	2.291e-61	220.0	COG0400@1|root,COG0400@2|Bacteria,2INMY@201174|Actinobacteria,4CTAJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	DLH
GDHHQS2_k127_2439565_6	251229.Chro_1450	5.052e-116	381.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
GDHHQS2_k127_2439565_12	861299.J421_1595	3.507e-64	230.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
GDHHQS2_k127_2439565_9	926550.CLDAP_34140	1.642e-92	332.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
GDHHQS2_k127_2439565_11	861299.J421_0442	1.342e-69	240.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2439565_22	861299.J421_0441	2.392e-25	120.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_2439565_4	861299.J421_1669	1.536e-145	466.0	COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2439565_19	861299.J421_1705	1.219e-49	187.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2
GDHHQS2_k127_2439565_16	861299.J421_1707	7.627e-57	203.0	COG1514@1|root,COG1514@2|Bacteria,1ZTNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
GDHHQS2_k127_2439565_18	1379270.AUXF01000001_gene2184	1.713e-50	193.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_2439565_20	1267533.KB906734_gene4053	3.992e-49	186.0	2EFRH@1|root,339HI@2|Bacteria,3Y7RW@57723|Acidobacteria,2JN1K@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2439565_1	502025.Hoch_5309	2.058e-255	797.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS2_k127_2439565_25	240015.ACP_3398	1.753e-06	57.0	2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria,2JJW7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2439565_10	861299.J421_2327	1.227e-70	246.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
GDHHQS2_k127_2439565_7	861299.J421_5793	5.823e-115	380.0	COG1680@1|root,COG1680@2|Bacteria,1ZUWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2439565_3	937777.Deipe_2643	1.169e-168	541.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS2_k127_2439565_5	1227739.Hsw_1849	1.457e-140	462.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47TTT@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_2439565_14	1504981.KO116_1432	1.443e-60	218.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	abc transporter atp-binding protein	yehX	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iECED1_1282.ECED1_2573,iEcE24377_1341.EcE24377A_2418,iPC815.YPO1198	ABC_tran,CBS
GDHHQS2_k127_2439565_8	1265313.HRUBRA_02839	8.423e-100	346.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycine betaine	opuCC	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
GDHHQS2_k127_2439565_15	861299.J421_1866	2.02e-58	213.0	28P9J@1|root,2ZC30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2439565_2	379066.GAU_1432	2.542e-188	602.0	COG0531@1|root,COG0531@2|Bacteria,1ZSUB@142182|Gemmatimonadetes	2|Bacteria	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_2478745_3	861299.J421_4358	6.061e-18	88.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2478745_1	861299.J421_4361	5.041e-81	277.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS2_k127_2478745_2	1379270.AUXF01000001_gene2648	3.642e-52	195.0	COG0589@1|root,COG0589@2|Bacteria,1ZTUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_2478745_0	379066.GAU_2714	5.875e-191	602.0	COG1914@1|root,COG1914@2|Bacteria,1ZT3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
GDHHQS2_k127_2499792_1	1200792.AKYF01000010_gene2718	1.56e-41	159.0	COG4538@1|root,COG4538@2|Bacteria,1V7Q1@1239|Firmicutes,4HJ77@91061|Bacilli,272NS@186822|Paenibacillaceae	91061|Bacilli	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
GDHHQS2_k127_2499792_2	1234364.AMSF01000013_gene680	5.181e-24	106.0	2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria,1SDGA@1236|Gammaproteobacteria,1X89Q@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2499792_3	304371.MCP_1150	3.773e-13	78.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
GDHHQS2_k127_2499792_0	861299.J421_1674	5.637e-234	739.0	COG1472@1|root,COG1472@2|Bacteria,1ZUGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS2_k127_2506755_1	861299.J421_5713	1.546e-137	449.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2506755_3	861299.J421_6107	6.95e-39	152.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
GDHHQS2_k127_2506755_0	861299.J421_2986	2.514e-218	688.0	COG0008@1|root,COG0008@2|Bacteria,1ZSSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS2_k127_2506755_2	861299.J421_2985	3.626e-66	232.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_2506755_4	502025.Hoch_4319	1.185e-21	100.0	COG0346@1|root,COG0346@2|Bacteria,1NB98@1224|Proteobacteria	1224|Proteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_2506755_5	861299.J421_2984	7.921e-08	57.0	2FFNT@1|root,347K5@2|Bacteria,1ZTY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2517869_1	861299.J421_3198	4.353e-99	327.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
GDHHQS2_k127_2517869_5	861299.J421_3199	1.64e-44	167.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
GDHHQS2_k127_2517869_2	1379270.AUXF01000005_gene834	9.976e-85	306.0	COG0652@1|root,COG0652@2|Bacteria,1ZUUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS2_k127_2517869_4	861299.J421_3201	4.987e-58	207.0	2EPTK@1|root,33HE4@2|Bacteria,1ZTUK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
GDHHQS2_k127_2517869_3	861299.J421_3202	3.722e-60	213.0	COG0615@1|root,COG0615@2|Bacteria,1ZTPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GDHHQS2_k127_2517869_0	1379270.AUXF01000005_gene838	2.208e-111	364.0	COG0689@1|root,COG0689@2|Bacteria,1ZSYT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GDHHQS2_k127_2517869_6	379066.GAU_1572	5.241e-39	158.0	COG0127@1|root,COG0127@2|Bacteria,1ZTSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS2_k127_2551602_6	861299.J421_2341	8.941e-51	184.0	2F2MH@1|root,33VI3@2|Bacteria,1ZTMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2551602_4	1379270.AUXF01000002_gene1784	2.865e-186	597.0	COG1158@1|root,COG1158@2|Bacteria,1ZTA0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
GDHHQS2_k127_2551602_8	335543.Sfum_0758	4.699e-32	145.0	COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS2_k127_2551602_0	861299.J421_2339	0.0	1155.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS2_k127_2551602_2	658187.LDG_5060	6.701e-212	672.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,1JCZW@118969|Legionellales	118969|Legionellales	I	Acyl-CoA dehydrogenase, middle domain	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
GDHHQS2_k127_2551602_5	861299.J421_1663	7.454e-152	488.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GDHHQS2_k127_2551602_7	240292.Ava_3892	1.237e-40	159.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HM2J@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS2_k127_2551602_1	861299.J421_2337	4.076e-215	677.0	COG0624@1|root,COG0624@2|Bacteria,1ZT2K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_2551602_9	1246459.KB898379_gene3529	1.075e-26	113.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,4BESE@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS2_k127_2551602_3	861299.J421_2334	1.604e-196	625.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS2_k127_2576116_1	379066.GAU_0239	2.812e-05	46.0	2E0UX@1|root,32WC9@2|Bacteria,1ZUE1@142182|Gemmatimonadetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GDHHQS2_k127_2576116_0	861299.J421_4062	4.315e-150	494.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2597679_1	861299.J421_4433	1.032e-103	347.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2597679_3	937777.Deipe_0047	1.982e-42	162.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	GO:0003674,GO:0005488,GO:0005515,GO:0006275,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0042802,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:2000105,GO:2000112	2.7.1.167,2.7.1.33,2.7.7.70,5.3.1.28	ko:K03271,ko:K03272,ko:K03525,ko:K12961	ko00540,ko00770,ko01100,map00540,map00770,map01100	M00064,M00120	R02971,R03018,R04391,R05644,R05645,R05646,R09768,R09769	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
GDHHQS2_k127_2597679_2	1341151.ASZU01000025_gene2986	2.685e-49	189.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,27B0F@186824|Thermoactinomycetaceae	91061|Bacilli	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
GDHHQS2_k127_2597679_0	379066.GAU_2758	1.405e-177	568.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GDHHQS2_k127_2748011_10	861299.J421_3898	5.482e-13	72.0	COG0151@1|root,COG0151@2|Bacteria,1ZSY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
GDHHQS2_k127_2748011_3	861299.J421_3896	1.994e-196	619.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_2748011_2	861299.J421_3894	7.036e-208	657.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_2748011_0	379066.GAU_2427	3.166e-303	942.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS2_k127_2748011_7	861299.J421_3872	1.266e-56	203.0	COG1490@1|root,COG1490@2|Bacteria,1ZTVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS2_k127_2748011_6	861299.J421_3871	8.211e-69	239.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS2_k127_2748011_9	670487.Ocepr_0499	1.095e-24	111.0	COG1051@1|root,COG1051@2|Bacteria,1WNG1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_2748011_4	861299.J421_3870	1.051e-151	487.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_2748011_8	861299.J421_3869	8.979e-42	166.0	COG3642@1|root,COG3642@2|Bacteria,1ZTTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
GDHHQS2_k127_2748011_1	861299.J421_3867	1.455e-220	694.0	COG0147@1|root,COG0147@2|Bacteria,1ZSPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS2_k127_2748011_5	861299.J421_3866	8.531e-151	490.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2755907_1	861299.J421_3829	1.762e-137	449.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
GDHHQS2_k127_2755907_0	1040989.AWZU01000125_gene3972	1.052e-224	702.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
GDHHQS2_k127_2755907_3	1122137.AQXF01000001_gene2835	5.651e-18	87.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
GDHHQS2_k127_2755907_4	215803.DB30_8595	4.141e-06	57.0	COG3591@1|root,COG3591@2|Bacteria,1Q1GX@1224|Proteobacteria,439CQ@68525|delta/epsilon subdivisions,2X4M4@28221|Deltaproteobacteria,2YZ8H@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2755907_2	204669.Acid345_3584	3.35e-39	150.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_2758848_4	861299.J421_3313	4.321e-46	170.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS2_k127_2758848_2	861299.J421_3314	7.201e-100	330.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
GDHHQS2_k127_2758848_3	379066.GAU_1684	8.525e-100	331.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
GDHHQS2_k127_2758848_0	861299.J421_3316	2.641e-231	729.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
GDHHQS2_k127_2758848_1	379066.GAU_1686	3.147e-195	619.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS2_k127_2758848_5	316067.Geob_3525	5.607e-22	96.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_2767396_0	861299.J421_4119	1.554e-220	692.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS2_k127_2767396_1	379066.GAU_2138	3.337e-73	255.0	COG2859@1|root,COG2859@2|Bacteria,1ZUNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS2_k127_2767396_2	573065.Astex_2113	6.084e-31	124.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2KI6R@204458|Caulobacterales	204458|Caulobacterales	E	leukotriene A-4 hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS2_k127_2780605_1	1121324.CLIT_23c01000	6.967e-103	340.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25QFC@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GDHHQS2_k127_2780605_0	379066.GAU_2412	2.206e-145	473.0	COG0466@1|root,COG0466@2|Bacteria,1ZT5P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_281105_0	861299.J421_2767	0.0	2147.0	COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS2_k127_281105_3	861299.J421_2766	1.397e-45	168.0	COG0222@1|root,COG0222@2|Bacteria,1ZTTC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS2_k127_281105_2	861299.J421_2765	7.8e-67	239.0	COG0244@1|root,COG0244@2|Bacteria,1ZTQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GDHHQS2_k127_281105_1	861299.J421_2764	1.622e-112	368.0	COG0081@1|root,COG0081@2|Bacteria,1ZSS7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS2_k127_281105_4	861299.J421_2763	2.354e-08	55.0	COG0080@1|root,COG0080@2|Bacteria,1ZTQZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS2_k127_2811560_0	264198.Reut_B3494	5.873e-200	636.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria,1K08R@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_2811560_2	861299.J421_1419	1.253e-42	173.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2811560_1	861299.J421_2387	1.851e-119	395.0	COG1680@1|root,COG1680@2|Bacteria,1ZV34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2811560_5	1337936.IJ00_00910	6.072e-18	98.0	2EFPZ@1|root,339G0@2|Bacteria,1GCBN@1117|Cyanobacteria,1HIZK@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2811560_3	8496.XP_006262675.1	1.84e-36	150.0	COG1864@1|root,KOG3721@2759|Eukaryota,38E5K@33154|Opisthokonta,3BD2Y@33208|Metazoa,3CVAJ@33213|Bilateria,485XE@7711|Chordata,490AJ@7742|Vertebrata	33208|Metazoa	F	neuron death in response to oxidative stress	ENDOG	GO:0000001,GO:0000003,GO:0000737,GO:0001701,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004536,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006308,GO:0006309,GO:0006310,GO:0006401,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006996,GO:0007005,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009790,GO:0009792,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010604,GO:0010623,GO:0010941,GO:0010942,GO:0012501,GO:0016043,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022411,GO:0022412,GO:0022414,GO:0030154,GO:0030262,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032501,GO:0032502,GO:0032504,GO:0034097,GO:0034612,GO:0034641,GO:0034645,GO:0034655,GO:0035234,GO:0036477,GO:0042221,GO:0042802,GO:0042803,GO:0042981,GO:0043009,GO:0043025,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044297,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045935,GO:0046483,GO:0046677,GO:0046700,GO:0046983,GO:0048232,GO:0048308,GO:0048311,GO:0048468,GO:0048515,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0097194,GO:0097458,GO:0140097,GO:0140098,GO:1900117,GO:1900119,GO:1900407,GO:1900409,GO:1901031,GO:1901033,GO:1901298,GO:1901300,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576,GO:1902510,GO:1902512,GO:1902882,GO:1902884,GO:1903201,GO:1903205,GO:1903209,GO:1903624,GO:1903626,GO:1905206,GO:2001023,GO:2001025,GO:2001038,GO:2001040	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS2_k127_2811560_6	383372.Rcas_2650	7.375e-11	70.0	COG1864@1|root,COG1864@2|Bacteria	2|Bacteria	F	neuron death in response to oxidative stress	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclea_NS_2,Endonuclease_NS,Excalibur
GDHHQS2_k127_2811560_4	292564.Cyagr_1917	1.151e-23	111.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,Peptidase_C13,Peptidase_C14
GDHHQS2_k127_2811560_7	292564.Cyagr_2553	2.283e-05	49.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
GDHHQS2_k127_2811967_14	593750.Metfor_1391	1.048e-15	81.0	COG1970@1|root,arCOG05213@2157|Archaea,2XZ6U@28890|Euryarchaeota,2N9XV@224756|Methanomicrobia	224756|Methanomicrobia	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS2_k127_2811967_12	1038860.AXAP01000005_gene8006	8.871e-30	128.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TX72@28211|Alphaproteobacteria,3K3KE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
GDHHQS2_k127_2811967_9	1396418.BATQ01000005_gene1388	1.812e-45	177.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS2_k127_2811967_1	1379270.AUXF01000001_gene2645	1.34e-196	648.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GDHHQS2_k127_2811967_2	861299.J421_0892	4.507e-167	539.0	COG0076@1|root,COG0076@2|Bacteria,1ZTFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
GDHHQS2_k127_2811967_7	861299.J421_1157	7.918e-75	261.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GDHHQS2_k127_2811967_3	861299.J421_0110	8.339e-135	442.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2811967_0	1267535.KB906767_gene1077	3.83e-245	778.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria	57723|Acidobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_2811967_10	861299.J421_1942	3.049e-45	171.0	COG1937@1|root,COG1937@2|Bacteria,1ZTZF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS2_k127_2811967_11	379066.GAU_0242	1.214e-38	153.0	2F4AY@1|root,33YV0@2|Bacteria,1ZU13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2811967_13	1379270.AUXF01000001_gene2214	6.792e-22	97.0	2F75B@1|root,33ZKU@2|Bacteria,1ZTZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2811967_5	1210884.HG799466_gene13015	4.895e-102	340.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_2811967_8	754035.Mesau_04046	2.566e-52	192.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,43JN0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS2_k127_2811967_4	861299.J421_3797	1.497e-109	364.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS2_k127_2811967_6	861299.J421_3794	3.387e-76	261.0	COG0693@1|root,COG0693@2|Bacteria,1ZU4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS2_k127_2818246_3	1379270.AUXF01000001_gene2650	1.832e-08	56.0	COG4591@1|root,COG4591@2|Bacteria	1379270.AUXF01000001_gene2650|-	M	lipoprotein localization to outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2818246_0	861299.J421_4357	8.722e-124	407.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2818246_1	861299.J421_4356	2.779e-93	315.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_2818246_2	861299.J421_4355	7.409e-86	292.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2823926_1	861299.J421_2770	1.966e-81	272.0	COG0049@1|root,COG0049@2|Bacteria,1ZSQZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS2_k127_2823926_2	926560.KE387027_gene344	8.299e-38	153.0	COG3291@1|root,COG3291@2|Bacteria,1WMHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
GDHHQS2_k127_2823926_0	861299.J421_3037	1.288e-237	743.0	COG1012@1|root,COG1012@2|Bacteria,1ZUF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_2823926_3	34506.g3684	1.663e-05	48.0	COG0167@1|root,KOG1799@2759|Eukaryota,3AHGF@33154|Opisthokonta,3BDZE@33208|Metazoa,3CRSR@33213|Bilateria,40G0T@6231|Nematoda,1KY4F@119089|Chromadorea,40THS@6236|Rhabditida	33208|Metazoa	F	Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine	DPYD	GO:0000166,GO:0002054,GO:0002058,GO:0002061,GO:0003674,GO:0003824,GO:0004159,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006145,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006213,GO:0006214,GO:0006725,GO:0006807,GO:0007568,GO:0007584,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009116,GO:0009120,GO:0009164,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010181,GO:0014070,GO:0016491,GO:0016627,GO:0016628,GO:0017113,GO:0017144,GO:0019439,GO:0019859,GO:0019860,GO:0031667,GO:0031960,GO:0032502,GO:0032553,GO:0033993,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0042221,GO:0042493,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046113,GO:0046121,GO:0046125,GO:0046127,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048511,GO:0048545,GO:0050660,GO:0050661,GO:0050662,GO:0050896,GO:0051384,GO:0055086,GO:0055114,GO:0071704,GO:0071949,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	1.3.1.2	ko:K00207	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00978,R01415,R08226	RC00072,RC00123,RC02245	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_20,Fer4_21,NAD_binding_8,Pyr_redox_2
GDHHQS2_k127_2826797_0	378806.STAUR_7575	0.0	1722.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2Z3GS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2826797_9	867845.KI911784_gene2126	8.764e-50	182.0	COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi	200795|Chloroflexi	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
GDHHQS2_k127_2826797_5	861299.J421_0072	1.935e-97	332.0	COG0116@1|root,COG0116@2|Bacteria,1ZT80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	UPF0020
GDHHQS2_k127_2826797_1	861299.J421_0079	1.46e-223	702.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	2|Bacteria	L	RecQ zinc-binding	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,HRDC,Helicase_C,RecQ_Zn_bind
GDHHQS2_k127_2826797_11	1123368.AUIS01000030_gene1247	7.222e-44	166.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
GDHHQS2_k127_2826797_13	498848.TaqDRAFT_3718	9.626e-37	143.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS2_k127_2826797_8	1379270.AUXF01000002_gene1709	2.367e-55	197.0	COG2166@1|root,COG2166@2|Bacteria,1ZTPH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
GDHHQS2_k127_2826797_14	278963.ATWD01000001_gene1694	6.045e-29	121.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria,2JJNM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2826797_15	861299.J421_5835	2.7e-24	109.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_2826797_12	1449049.JONW01000011_gene2311	6.97e-37	148.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2826797_16	204669.Acid345_3258	1.782e-18	88.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS2_k127_2826797_6	861299.J421_2603	2.555e-79	269.0	COG0432@1|root,COG0432@2|Bacteria,1ZV8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS2_k127_2826797_10	861299.J421_0105	1.567e-45	173.0	28NRS@1|root,2ZBQZ@2|Bacteria,1ZV13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2826797_4	1297742.A176_01806	6.75e-108	360.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2826797_3	1128421.JAGA01000002_gene905	2.26e-137	451.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
GDHHQS2_k127_2826797_7	861299.J421_0149	9.958e-79	269.0	COG0122@1|root,COG0122@2|Bacteria,1ZTST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS2_k127_2826797_2	1382306.JNIM01000001_gene1966	4.571e-172	553.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS2_k127_2828182_1	861299.J421_2745	4.874e-39	148.0	COG1324@1|root,COG1324@2|Bacteria,1ZV6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS2_k127_2828182_0	861299.J421_3844	2.142e-52	188.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS2_k127_2837280_1	379066.GAU_3334	1.786e-35	140.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2837280_0	1123508.JH636439_gene1391	3.676e-134	465.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_2837280_3	1500894.JQNN01000001_gene4339	1.899e-05	56.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cu_amine_oxidN1,NHL,Pkinase
GDHHQS2_k127_2837280_2	1469557.JSWF01000014_gene2487	3.827e-27	114.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
GDHHQS2_k127_2846140_3	981369.JQMJ01000004_gene2626	1.58e-75	269.0	COG0121@1|root,COG4301@1|root,COG0121@2|Bacteria,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,2NGCU@228398|Streptacidiphilus	201174|Actinobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	GATase_6,Methyltransf_33
GDHHQS2_k127_2846140_0	266117.Rxyl_0687	1.774e-142	465.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
GDHHQS2_k127_2846140_4	266117.Rxyl_0513	4.299e-69	250.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4CQ62@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_2846140_6	861299.J421_5909	5.057e-57	224.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5909|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2846140_5	426117.M446_0742	6.562e-63	227.0	COG0063@1|root,COG0063@2|Bacteria,1RDYQ@1224|Proteobacteria,2U7VX@28211|Alphaproteobacteria,1JTN0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
GDHHQS2_k127_2846140_2	1123060.JONP01000014_gene4167	2.181e-89	303.0	COG0406@1|root,COG0406@2|Bacteria,1RAPQ@1224|Proteobacteria,2U0U1@28211|Alphaproteobacteria,2JVC1@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS2_k127_2846140_1	861299.J421_2320	3.45e-99	341.0	COG4783@1|root,COG4783@2|Bacteria,1ZT4T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2861817_7	1408427.JADB01000015_gene1457	3.866e-24	102.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,48TEI@772|Bartonellaceae	28211|Alphaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2861817_9	1122921.KB898209_gene2653	1.242e-05	49.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2861817_3	861299.J421_3205	8.287e-114	376.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GDHHQS2_k127_2861817_8	861299.J421_3206	2.577e-20	97.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
GDHHQS2_k127_2861817_5	1379270.AUXF01000006_gene314	1.026e-59	218.0	COG1159@1|root,COG1159@2|Bacteria,1ZU0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2861817_4	861299.J421_3209	4.959e-103	345.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS2_k127_2861817_6	1379270.AUXF01000006_gene311	4.797e-48	184.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
GDHHQS2_k127_2861817_1	1379270.AUXF01000006_gene310	1.956e-154	494.0	COG1186@1|root,COG1186@2|Bacteria,1ZTE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_2861817_0	379066.GAU_1579	3.065e-233	737.0	COG1190@1|root,COG1190@2|Bacteria,1ZT9X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_2861817_2	379066.GAU_1580	4.276e-125	411.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2879388_0	861299.J421_4036	9.708e-185	591.0	COG4774@1|root,COG4774@2|Bacteria,1ZTSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_2879388_3	861299.J421_2117	7.344e-113	373.0	COG0492@1|root,COG0492@2|Bacteria,1ZV3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GDHHQS2_k127_2879388_9	1247963.JPHU01000008_gene2779	1.081e-07	63.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	dop	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_2879388_8	861299.J421_2115	1.761e-19	96.0	2F7PW@1|root,34048@2|Bacteria,1ZTZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2879388_5	1379270.AUXF01000001_gene2409	1.866e-72	249.0	COG1595@1|root,COG1595@2|Bacteria,1ZTJF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2879388_1	861299.J421_2113	1.447e-159	514.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_2879388_6	861299.J421_2112	5.605e-41	154.0	COG2151@1|root,COG2151@2|Bacteria,1ZTUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS2_k127_2879388_2	1379270.AUXF01000001_gene2405	4.917e-158	506.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS2_k127_2879388_7	861299.J421_2107	3.353e-35	139.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2
GDHHQS2_k127_2879388_4	1379270.AUXF01000001_gene2402	5.02e-79	268.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_2883597_0	1120950.KB892767_gene5169	3.725e-25	107.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DTC9@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_2883597_1	204669.Acid345_2162	1.009e-09	70.0	COG1462@1|root,COG1462@2|Bacteria,3Y3KF@57723|Acidobacteria	57723|Acidobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS2_k127_2883597_2	861299.J421_3680	2.905e-06	53.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
GDHHQS2_k127_2889684_4	861299.J421_5988	5.583e-28	115.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS2_k127_2889684_1	861299.J421_5989	4.064e-102	337.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS2_k127_2889684_3	861299.J421_4305	3.269e-31	129.0	COG0614@1|root,COG0614@2|Bacteria,1ZV3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GDHHQS2_k127_2889684_0	861299.J421_0715	4.525e-159	518.0	COG0642@1|root,COG0642@2|Bacteria,1ZUEC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
GDHHQS2_k127_2889684_2	1454004.AW11_01694	2.683e-32	129.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria	1224|Proteobacteria	T	PFAM KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
GDHHQS2_k127_2895516_0	1379698.RBG1_1C00001G0629	7.131e-210	670.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
GDHHQS2_k127_2895516_1	861299.J421_3930	2.187e-139	456.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS2_k127_2895516_2	861299.J421_3931	1.543e-101	336.0	COG2086@1|root,COG2086@2|Bacteria,1ZT51@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS2_k127_2895516_3	861299.J421_0318	1.274e-21	106.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_2900397_8	1265502.KB905938_gene2432	4.722e-10	64.0	2DT41@1|root,33IK2@2|Bacteria,1NNPM@1224|Proteobacteria,2W6H7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2900397_3	1449976.KALB_3518	1.856e-47	182.0	COG0461@1|root,COG0461@2|Bacteria,2H5SI@201174|Actinobacteria,4EBR1@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_2900397_9	1265845.PWEIH_07006	3.596e-08	63.0	COG5350@1|root,COG5350@2|Bacteria,1VRYA@1239|Firmicutes,4HTIP@91061|Bacilli,26KFN@186820|Listeriaceae	91061|Bacilli	S	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
GDHHQS2_k127_2900397_2	861299.J421_0809	5.951e-54	199.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_2900397_5	1122179.KB890415_gene1985	2.995e-22	98.0	2A0AF@1|root,2ZQ9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2900397_1	663610.JQKO01000013_gene1806	2.238e-177	568.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,3N9Q5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
GDHHQS2_k127_2900397_6	1122927.KB895412_gene875	3.779e-22	100.0	COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli,26Z6R@186822|Paenibacillaceae	91061|Bacilli	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
GDHHQS2_k127_2900397_0	290317.Cpha266_2588	1.325e-182	588.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2904869_4	1379270.AUXF01000006_gene193	1.863e-14	74.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GDHHQS2_k127_2904869_2	1191523.MROS_1725	6.52e-121	406.0	COG1530@1|root,COG1530@2|Bacteria	2|Bacteria	J	ribonuclease E activity	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
GDHHQS2_k127_2904869_3	861299.J421_3339	2.73e-58	208.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_2904869_1	861299.J421_3340	2.667e-203	638.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_2904869_0	517418.Ctha_1907	1.321e-241	773.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_2926411_2	861299.J421_4248	2.765e-96	323.0	COG0603@1|root,COG0603@2|Bacteria,1ZT7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS2_k127_2926411_1	861299.J421_4249	1.019e-98	327.0	COG0602@1|root,COG0602@2|Bacteria,1ZT5J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	-
GDHHQS2_k127_2926411_0	1128421.JAGA01000003_gene2811	9.945e-148	478.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2926411_3	861299.J421_2433	5.811e-47	171.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_2931000_0	861299.J421_5841	1.356e-79	281.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like_2
GDHHQS2_k127_2931000_2	861299.J421_4229	1.741e-17	91.0	COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Caps_assemb_Wzi
GDHHQS2_k127_2931000_1	861299.J421_2638	1.485e-52	188.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2638|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2931000_3	861299.J421_2639	1.28e-14	76.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	2.6.1.85	ko:K13950,ko:K21025	ko00790,ko02025,map00790,map02025	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
GDHHQS2_k127_2959667_2	861299.J421_3570	6.762e-165	541.0	COG0399@1|root,COG0399@2|Bacteria,1ZT81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_2959667_1	1379270.AUXF01000003_gene3890	9.951e-180	567.0	COG0673@1|root,COG0673@2|Bacteria,1ZSQ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS2_k127_2959667_3	515635.Dtur_0577	2.378e-79	272.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
GDHHQS2_k127_2959667_0	861299.J421_3571	6.172e-315	974.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS2_k127_2972455_9	1267535.KB906767_gene3833	8.749e-36	139.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	2|Bacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_2972455_5	861299.J421_1337	1.547e-81	281.0	28K2C@1|root,2Z9RQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2972455_1	861299.J421_1338	3.47e-218	689.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_2972455_7	1179773.BN6_32750	2.428e-60	214.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4E3XG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2972455_0	1379270.AUXF01000001_gene2262	7.462e-297	917.0	COG2303@1|root,COG2303@2|Bacteria,1ZSZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_2972455_8	1379270.AUXF01000001_gene2261	5.656e-54	199.0	2CDAN@1|root,3134Z@2|Bacteria,1ZU58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS2_k127_2972455_2	929713.NIASO_05495	1.394e-116	383.0	COG2133@1|root,COG2133@2|Bacteria,4PNNH@976|Bacteroidetes	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_2972455_3	296591.Bpro_2932	2.813e-110	365.0	COG0715@1|root,COG0715@2|Bacteria,1PF0I@1224|Proteobacteria,2VZE8@28216|Betaproteobacteria,4AIXD@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
GDHHQS2_k127_2972455_4	1502852.FG94_03655	1.346e-92	311.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2VJ3H@28216|Betaproteobacteria,476TV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	tauC	-	-	ko:K02050,ko:K15552,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00435,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4	-	-	BPD_transp_1
GDHHQS2_k127_2972455_6	760117.JN27_01920	2.016e-72	252.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2W97I@28216|Betaproteobacteria,475FN@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_2977573_0	1380394.JADL01000008_gene3516	9.742e-177	563.0	COG0151@1|root,COG0151@2|Bacteria,1NEZN@1224|Proteobacteria,2UP1I@28211|Alphaproteobacteria,2JVQF@204441|Rhodospirillales	204441|Rhodospirillales	F	Phosphoribosylglycinamide synthetase, C domain	-	-	-	-	-	-	-	-	-	-	-	-	GARS_A
GDHHQS2_k127_2977573_3	426117.M446_1674	2.858e-49	189.0	COG2265@1|root,COG2265@2|Bacteria,1R06J@1224|Proteobacteria,2TYKF@28211|Alphaproteobacteria,1JX9J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_2977573_2	1380394.JADL01000002_gene1704	1.38e-64	229.0	COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,2U5RW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS2_k127_2977573_1	1288494.EBAPG3_30800	4.959e-160	514.0	COG0620@1|root,COG0620@2|Bacteria,1PWDP@1224|Proteobacteria,2WBYB@28216|Betaproteobacteria,3740I@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS2_k127_2986505_35	404589.Anae109_1512	1.224e-37	146.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_40	379066.GAU_1343	1.366e-31	133.0	COG0457@1|root,COG0457@2|Bacteria,1ZUVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS2_k127_2986505_44	1128421.JAGA01000001_gene2028	2.709e-25	113.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
GDHHQS2_k127_2986505_0	861299.J421_2847	0.0	1334.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
GDHHQS2_k127_2986505_1	861299.J421_2845	4.245e-272	871.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSWP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_2986505_22	861299.J421_2844	6.91e-117	396.0	COG0860@1|root,COG0860@2|Bacteria,1ZT6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS2_k127_2986505_32	1379270.AUXF01000004_gene2956	2.837e-63	227.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS2_k127_2986505_12	1173027.Mic7113_3322	4.623e-161	518.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1H9RK@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
GDHHQS2_k127_2986505_24	1379270.AUXF01000004_gene2957	9.151e-115	390.0	COG1472@1|root,COG1472@2|Bacteria,1ZST8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3
GDHHQS2_k127_2986505_14	861299.J421_2839	9.059e-149	479.0	COG2377@1|root,COG2377@2|Bacteria,1ZSZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
GDHHQS2_k127_2986505_20	861299.J421_2838	7.552e-118	387.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS2_k127_2986505_46	1379270.AUXF01000004_gene2960	1.634e-18	94.0	2BBF1@1|root,324YA@2|Bacteria,1ZUV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_7	1379270.AUXF01000004_gene2961	1.31e-197	632.0	COG0405@1|root,COG0405@2|Bacteria,1ZT0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_2986505_29	861299.J421_2835	4.922e-75	261.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_3	861299.J421_2834	2.664e-234	738.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_2986505_28	861299.J421_2833	3.5e-98	331.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_2833|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_48	375451.RD1_3462	3.203e-13	74.0	COG0745@1|root,COG0745@2|Bacteria,1NCKY@1224|Proteobacteria,2TRPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2986505_27	1232410.KI421421_gene3566	5.605e-99	353.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_2986505_45	861299.J421_2827	4.738e-24	108.0	2FCS2@1|root,344V7@2|Bacteria,1ZU5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_8	1144275.COCOR_00398	1.185e-188	594.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
GDHHQS2_k127_2986505_16	1379270.AUXF01000002_gene1601	2.119e-136	449.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS2_k127_2986505_10	1444309.JAQG01000005_gene4298	6.014e-167	552.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26R54@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS2_k127_2986505_19	861299.J421_2824	3.552e-122	401.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS2_k127_2986505_25	861299.J421_2823	2.259e-114	377.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2986505_23	379066.GAU_0922	7.635e-116	383.0	COG0598@1|root,COG0598@2|Bacteria,1ZSKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS2_k127_2986505_15	861299.J421_2819	6.441e-142	459.0	COG0123@1|root,COG0123@2|Bacteria,1ZSKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_2986505_47	379066.GAU_0914	1.799e-15	82.0	2C3VP@1|root,2ZRAS@2|Bacteria,1ZU7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_43	861299.J421_2817	3.725e-27	113.0	2FC5K@1|root,3449E@2|Bacteria,1ZU4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2986505_9	945713.IALB_0608	6.141e-168	552.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
GDHHQS2_k127_2986505_26	1128421.JAGA01000002_gene1381	1.726e-105	357.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
GDHHQS2_k127_2986505_11	861299.J421_2812	1.189e-165	536.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
GDHHQS2_k127_2986505_4	379066.GAU_0909	3.365e-233	727.0	COG0423@1|root,COG0423@2|Bacteria,1ZT4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
GDHHQS2_k127_2986505_17	861299.J421_2808	2.584e-135	439.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GDHHQS2_k127_2986505_5	861299.J421_2807	1.44e-224	702.0	COG0104@1|root,COG0104@2|Bacteria,1ZSNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS2_k127_2986505_2	861299.J421_0935	2.571e-242	770.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_2986505_36	861299.J421_0936	7.997e-36	139.0	arCOG03092@1|root,32YMQ@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS2_k127_2986505_39	861299.J421_0937	3.221e-32	128.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS2_k127_2986505_42	861299.J421_0938	1.834e-30	131.0	arCOG06390@1|root,330IR@2|Bacteria	2|Bacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle,GvpK
GDHHQS2_k127_2986505_50	1121422.AUMW01000016_gene2089	2.66e-05	55.0	2DJCY@1|root,305NK@2|Bacteria,1TYFT@1239|Firmicutes,256D7@186801|Clostridia,266HZ@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS2_k127_2986505_31	861299.J421_0941	8.089e-64	228.0	2C8AD@1|root,32RKP@2|Bacteria	2|Bacteria	S	Gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
GDHHQS2_k127_2986505_18	861299.J421_0944	3.389e-132	425.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS2_k127_2986505_34	379066.GAU_0906	2.136e-41	158.0	COG2839@1|root,COG2839@2|Bacteria,1ZUVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GDHHQS2_k127_2986505_13	861299.J421_2799	1.273e-155	497.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS2_k127_2986505_30	557598.LHK_00343	3.578e-69	247.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KQHE@206351|Neisseriales	206351|Neisseriales	G	Psort location Cytoplasmic, score 8.96	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_2986505_6	861299.J421_2797	2.182e-208	658.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,1ZT04@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS2_k127_2986505_49	765910.MARPU_13595	2.389e-05	53.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1WZI2@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_2986505_21	861299.J421_2796	1.23e-117	383.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS2_k127_2986505_41	379066.GAU_0894	2.566e-31	125.0	COG0563@1|root,COG0563@2|Bacteria,1ZTHC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
GDHHQS2_k127_3003430_2	246197.MXAN_2622	8.299e-41	155.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
GDHHQS2_k127_3003430_3	56107.Cylst_2200	3.573e-28	121.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HNP9@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GDHHQS2_k127_3003430_1	861299.J421_4188	6.847e-96	316.0	COG0221@1|root,COG0221@2|Bacteria,1ZTH9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
GDHHQS2_k127_3003430_0	42256.RradSPS_2139	1.69e-115	381.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_3007167_1	883126.HMPREF9710_00703	1.477e-47	178.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2VTYH@28216|Betaproteobacteria,4774B@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
GDHHQS2_k127_3007167_0	1183438.GKIL_3207	2.02e-79	283.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
GDHHQS2_k127_3007167_2	1121931.AUHG01000010_gene318	2.87e-47	177.0	COG3023@1|root,COG3876@1|root,COG3023@2|Bacteria,COG3876@2|Bacteria,4NIY6@976|Bacteroidetes,1I0U3@117743|Flavobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DUF1343
GDHHQS2_k127_3007167_3	468059.AUHA01000002_gene531	1.119e-21	97.0	29Z06@1|root,30KX7@2|Bacteria,4NZNI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS2_k127_300851_5	861299.J421_3454	1.001e-25	111.0	COG2172@1|root,COG2172@2|Bacteria,1ZU34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS2_k127_300851_4	861299.J421_3455	7.113e-54	190.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS2_k127_300851_1	861299.J421_3456	2.469e-87	297.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GDHHQS2_k127_300851_3	1379270.AUXF01000006_gene73	2.442e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,1ZTTQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS2_k127_300851_2	861299.J421_3458	7.507e-59	214.0	COG0742@1|root,COG0742@2|Bacteria,1ZTVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS2_k127_300851_0	1379270.AUXF01000006_gene71	4.197e-183	585.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS2_k127_3011134_2	1538295.JY96_08700	4.758e-84	287.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KJ8G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
GDHHQS2_k127_3011134_1	1128421.JAGA01000002_gene1230	2.872e-106	367.0	COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria	2|Bacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
GDHHQS2_k127_3011134_0	383372.Rcas_4148	9.341e-224	706.0	COG0467@1|root,COG0467@2|Bacteria,2G8TX@200795|Chloroflexi,376XI@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Circadian clock protein KaiC central region	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS2_k127_303172_4	1172186.KB911464_gene4940	8.766e-10	63.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,233HY@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
GDHHQS2_k127_303172_2	547163.BN979_02517	1.305e-30	125.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,233HY@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
GDHHQS2_k127_303172_0	1265502.KB905960_gene289	5.55e-142	461.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VHQF@28216|Betaproteobacteria,4ACST@80864|Comamonadaceae	28216|Betaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_303172_1	1150626.PHAMO_270280	2.615e-50	188.0	COG4122@1|root,COG4122@2|Bacteria,1N29F@1224|Proteobacteria,2UH13@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_303172_3	1249627.D779_4222	5.589e-15	76.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,1WWD7@135613|Chromatiales	135613|Chromatiales	GK	pfam rok	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
GDHHQS2_k127_3039180_0	1117108.PAALTS15_25134	2.786e-82	293.0	COG1672@1|root,COG1672@2|Bacteria,1VFHR@1239|Firmicutes,4HVCH@91061|Bacilli	91061|Bacilli	L	COG0470 ATPase involved in DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
GDHHQS2_k127_3039180_3	1453500.AT05_03710	7.732e-25	105.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
GDHHQS2_k127_3039180_2	661478.OP10G_3508	2.934e-52	193.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_3039180_1	429009.Adeg_1726	7.338e-78	270.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,42FCG@68295|Thermoanaerobacterales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_3039230_3	1320556.AVBP01000013_gene1464	2.55e-38	154.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U35E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
GDHHQS2_k127_3039230_5	1379270.AUXF01000007_gene892	8.019e-26	116.0	COG1246@1|root,COG1246@2|Bacteria,1ZTT2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GDHHQS2_k127_3039230_0	861299.J421_1419	1.229e-102	350.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3039230_1	861299.J421_1418	4.116e-75	278.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	2|Bacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT,HEAT_2,Paired_CXXCH_1,Peptidase_M56,TPR_19,TPR_8
GDHHQS2_k127_3039230_2	861299.J421_0308	1.494e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_3039991_0	1379270.AUXF01000005_gene790	7.208e-101	332.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS2_k127_3039991_1	379066.GAU_2223	6.149e-48	190.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1ZU32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
GDHHQS2_k127_3049096_6	861299.J421_1780	2.189e-33	133.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
GDHHQS2_k127_3049096_0	861299.J421_1779	4.378e-116	394.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_3049096_4	861299.J421_1778	4.36e-89	304.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS2_k127_3049096_1	861299.J421_1777	9.358e-116	389.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3049096_3	861299.J421_1776	1.172e-103	353.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3049096_2	861299.J421_1775	1.145e-109	376.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_3049096_5	861299.J421_1774	2.173e-48	184.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	2|Bacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_3066725_18	469383.Cwoe_1767	1.312e-56	205.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS2_k127_3066725_16	234267.Acid_6140	1.006e-67	237.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_25
GDHHQS2_k127_3066725_4	401053.AciPR4_1363	5.754e-209	657.0	COG0666@1|root,COG0666@2|Bacteria,3Y3EY@57723|Acidobacteria	57723|Acidobacteria	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_12	861299.J421_4544	2.105e-87	299.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_3066725_24	861299.J421_3990	1.292e-36	143.0	COG1186@1|root,COG1186@2|Bacteria,1ZTZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GDHHQS2_k127_3066725_11	1254432.SCE1572_33565	7.468e-91	311.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GDHHQS2_k127_3066725_13	204669.Acid345_0284	2.994e-85	289.0	COG1131@1|root,COG1131@2|Bacteria,3Y4CW@57723|Acidobacteria,2JMQR@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3066725_26	861299.J421_3991	5.881e-35	143.0	29F5I@1|root,30238@2|Bacteria,1ZU4C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_5	861299.J421_2044	4.131e-189	616.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_2	861299.J421_2060	1.347e-251	794.0	COG1012@1|root,COG1012@2|Bacteria,1ZSRK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS2_k127_3066725_22	861299.J421_2061	9.463e-41	160.0	2F7IP@1|root,33ZZA@2|Bacteria,1ZTTA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_33	682795.AciX8_4517	4.681e-06	57.0	COG1629@1|root,COG1629@2|Bacteria,3Y9BW@57723|Acidobacteria,2JP0H@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_3066725_8	861299.J421_2063	1.738e-118	387.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS2_k127_3066725_27	1247726.MIM_c09640	7.004e-30	124.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,3T4K8@506|Alcaligenaceae	28216|Betaproteobacteria	B	SWIB/MDM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
GDHHQS2_k127_3066725_9	861299.J421_2065	9.823e-116	379.0	COG0681@1|root,COG0681@2|Bacteria,1ZTFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS2_k127_3066725_28	861299.J421_2067	8.609e-28	121.0	2BYRT@1|root,345RZ@2|Bacteria,1ZU2R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_17	861299.J421_2070	5.85e-58	204.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
GDHHQS2_k127_3066725_10	379066.GAU_3054	3.846e-112	376.0	COG1668@1|root,COG1668@2|Bacteria,1ZTID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_3066725_7	861299.J421_2075	1.318e-154	494.0	COG4152@1|root,COG4152@2|Bacteria,1ZSSG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS2_k127_3066725_15	670292.JH26_03880	3.58e-70	246.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS2_k127_3066725_23	755732.Fluta_0862	1.54e-37	145.0	2C4H4@1|root,32CX0@2|Bacteria,4NX86@976|Bacteroidetes,1I5D2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_20	379066.GAU_0945	5.815e-55	205.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS2_k127_3066725_19	861299.J421_5956	1.937e-55	201.0	2CDAN@1|root,3134Z@2|Bacteria,1ZU58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS2_k127_3066725_0	861299.J421_5957	3.578e-309	955.0	COG2303@1|root,COG2303@2|Bacteria,1ZSZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_3066725_3	395495.Lcho_1954	4.672e-229	719.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KJ6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
GDHHQS2_k127_3066725_14	1379270.AUXF01000001_gene2755	3.128e-71	263.0	2EZKR@1|root,33SRW@2|Bacteria,1ZSQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066725_32	1144275.COCOR_01500	2.736e-14	74.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,42XZ1@68525|delta/epsilon subdivisions,2WTGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
GDHHQS2_k127_3066725_25	861299.J421_0746	1.782e-35	141.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_3066725_21	861299.J421_2084	2.983e-45	168.0	COG0822@1|root,COG0822@2|Bacteria,1ZTSD@142182|Gemmatimonadetes	2|Bacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS2_k127_3066725_6	861299.J421_2085	2.718e-186	589.0	COG0520@1|root,COG0520@2|Bacteria,1ZSYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_3066725_31	67257.JODR01000012_gene6086	6.941e-20	95.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS2_k127_3066725_1	861299.J421_2090	6.263e-266	823.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_3066725_30	78245.Xaut_4468	4.423e-22	99.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,3EYYW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	ATPases associated with a variety of cellular activities	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS2_k127_3077666_7	861299.J421_2881	2.811e-57	201.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS2_k127_3077666_6	861299.J421_2878	8.475e-102	340.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS2_k127_3077666_8	861299.J421_2877	9.571e-32	129.0	COG4980@1|root,COG4980@2|Bacteria,1ZU46@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS2_k127_3077666_1	861299.J421_2876	2.753e-189	603.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_3077666_0	379066.GAU_1107	8.624e-203	640.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
GDHHQS2_k127_3077666_2	861299.J421_2873	7.398e-184	585.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS2_k127_3077666_5	1379270.AUXF01000005_gene378	5.193e-102	340.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
GDHHQS2_k127_3077666_3	379066.GAU_1104	9.361e-184	592.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS2_k127_3077666_4	861299.J421_2867	4.112e-163	521.0	COG0176@1|root,COG0176@2|Bacteria,1ZSZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS2_k127_3077666_10	452637.Oter_2363	2.593e-15	79.0	2CFSQ@1|root,32S2E@2|Bacteria,46VN9@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3085397_4	1379270.AUXF01000002_gene1817	1.957e-97	326.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GDHHQS2_k127_3085397_3	1340493.JNIF01000003_gene3871	3.725e-98	340.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_3085397_7	234267.Acid_4549	2.943e-60	219.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3085397_5	316067.Geob_3393	2.145e-79	272.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_3085397_2	760192.Halhy_6459	3.651e-105	356.0	COG1680@1|root,COG1680@2|Bacteria,4PP29@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
GDHHQS2_k127_3085397_0	262724.TT_C1950	3.288e-188	595.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS2_k127_3085397_8	1122223.KB890687_gene2443	5.376e-58	203.0	COG0347@1|root,COG0347@2|Bacteria,1WJZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS2_k127_3085397_1	383372.Rcas_4246	6.37e-177	570.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,376G5@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS2_k127_3085397_9	323848.Nmul_A0637	5.098e-11	73.0	COG3103@1|root,COG3103@2|Bacteria,1NQ5X@1224|Proteobacteria,2WA5G@28216|Betaproteobacteria,372RR@32003|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM SH3, type 3	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS2_k127_3085397_6	1266925.JHVX01000003_gene499	1.537e-78	283.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WGWX@28216|Betaproteobacteria,37279@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
GDHHQS2_k127_3112420_12	743719.PaelaDRAFT_1340	9.386e-50	191.0	2BWG6@1|root,32WUM@2|Bacteria,1VBBF@1239|Firmicutes,4HNFJ@91061|Bacilli,26UFI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3112420_6	861299.J421_2514	2.805e-120	398.0	COG0477@1|root,COG2814@2|Bacteria,1ZSUR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS2_k127_3112420_0	861299.J421_2513	1.182e-222	700.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_3112420_11	546414.Deide_21390	3.196e-54	203.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GDHHQS2_k127_3112420_5	666685.R2APBS1_3302	5.432e-133	443.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1X5RA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_3112420_7	472759.Nhal_2486	4.609e-112	386.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS2_k127_3112420_9	861299.J421_1920	8.359e-90	301.0	COG2197@1|root,COG2197@2|Bacteria,1ZSRV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_3112420_13	1382356.JQMP01000003_gene1429	1.172e-45	184.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS2_k127_3112420_1	861299.J421_1919	1.915e-171	544.0	COG2132@1|root,COG2132@2|Bacteria,1ZTWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS2_k127_3112420_8	379066.GAU_2543	4.62e-109	373.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS2_k127_3112420_28	497965.Cyan7822_5120	1.901e-07	57.0	2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria,3KIS1@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3112420_21	379066.GAU_2093	1.377e-33	138.0	COG3467@1|root,COG3467@2|Bacteria,1ZU4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS2_k127_3112420_16	765420.OSCT_0546	1.718e-37	154.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_3112420_2	1379270.AUXF01000003_gene3360	4.427e-158	522.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	2|Bacteria	P	E1-E2 ATPase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
GDHHQS2_k127_3112420_23	1379270.AUXF01000007_gene905	4.678e-31	134.0	COG0589@1|root,COG0589@2|Bacteria,1ZUGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335,Usp
GDHHQS2_k127_3112420_29	936455.KI421499_gene1793	3.192e-05	55.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,3JYKK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS2_k127_3112420_20	379066.GAU_2093	7.843e-34	143.0	COG3467@1|root,COG3467@2|Bacteria,1ZU4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS2_k127_3112420_3	1288963.ADIS_2413	1.751e-144	479.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47N8C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3112420_25	861299.J421_5746	1.704e-23	109.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_3112420_14	479434.Sthe_1412	7.083e-45	171.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS2_k127_3112420_17	649638.Trad_0418	3.876e-37	152.0	COG2386@1|root,COG2386@2|Bacteria,1WIH9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ABC-type transport system involved in cytochrome c biogenesis permease component	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS2_k127_3112420_10	1144275.COCOR_03000	3.316e-58	210.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS2_k127_3112420_19	498848.TaqDRAFT_5116	6.907e-34	135.0	COG2332@1|root,COG2332@2|Bacteria,1WJVR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GDHHQS2_k127_3112420_4	1313172.YM304_09640	1.112e-138	467.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CMX6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS2_k127_3112420_22	40571.JOEA01000041_gene4666	5.509e-32	135.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4E3DR@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
GDHHQS2_k127_3112420_24	671143.DAMO_1586	9.013e-24	108.0	COG3088@1|root,COG3088@2|Bacteria,2NRBD@2323|unclassified Bacteria	2|Bacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH
GDHHQS2_k127_3112420_18	861299.J421_0446	5.102e-37	149.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3112420_26	1191523.MROS_2048	5.488e-19	101.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
GDHHQS2_k127_3112420_15	589924.Ferp_2107	9.922e-39	159.0	arCOG06549@1|root,arCOG06549@2157|Archaea,2Y31C@28890|Euryarchaeota,246R3@183980|Archaeoglobi	183980|Archaeoglobi	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
GDHHQS2_k127_3115623_0	861299.J421_2545	6.765e-307	983.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS2_k127_3115623_1	861299.J421_2544	1.119e-182	601.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS2_k127_3134794_1	861299.J421_3939	5.533e-11	64.0	COG2879@1|root,COG2879@2|Bacteria,1ZU6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
GDHHQS2_k127_3134794_0	861299.J421_5612	6.107e-70	248.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
GDHHQS2_k127_3136867_0	1123278.KB893433_gene672	3.46e-78	276.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,47NUC@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS2_k127_3136867_4	1340493.JNIF01000003_gene1683	0.0003132	49.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	CsgG,FlgT_C
GDHHQS2_k127_3136867_2	290397.Adeh_3812	1.579e-40	153.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,43AM1@68525|delta/epsilon subdivisions,2X616@28221|Deltaproteobacteria,2Z388@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_3136867_1	378806.STAUR_7457	1.057e-74	257.0	COG3832@1|root,COG3832@2|Bacteria,1MZXG@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_3136867_3	401053.AciPR4_0237	5.85e-14	72.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_3186_0	379066.GAU_1700	1.842e-171	549.0	COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
GDHHQS2_k127_3186_2	861299.J421_3337	5.811e-31	124.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GDHHQS2_k127_3186_1	497965.Cyan7822_1303	3.483e-31	124.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,3KI4G@43988|Cyanothece	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GDHHQS2_k127_3186_3	290317.Cpha266_2639	1.805e-23	104.0	2DNS7@1|root,32YWC@2|Bacteria,1FFKA@1090|Chlorobi	1090|Chlorobi	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_3186_4	861299.J421_3334	8.836e-21	93.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	861299.J421_3334|-	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3275381_3	861299.J421_4200	7.018e-41	154.0	COG0596@1|root,COG0596@2|Bacteria,1ZTSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_3275381_1	1379270.AUXF01000001_gene2790	5.868e-61	219.0	COG1651@1|root,COG1651@2|Bacteria,1ZTKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS2_k127_3275381_4	861299.J421_4261	1.527e-17	91.0	COG4243@1|root,COG4243@2|Bacteria,1ZTVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GDHHQS2_k127_3275381_2	861299.J421_4197	4.316e-46	169.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3275381_0	1267534.KB906759_gene1822	6.195e-71	249.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	mmpL3	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264	-	ko:K06994,ko:K07003,ko:K20466,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.5,2.A.6.5.6	-	-	MMPL
GDHHQS2_k127_3329113_2	32057.KB217478_gene7011	4.81e-115	379.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1HR77@1161|Nostocales	1117|Cyanobacteria	EU	Prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_3329113_1	861299.J421_4435	6.566e-168	533.0	COG0205@1|root,COG0205@2|Bacteria,1ZTAR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS2_k127_3329113_7	997346.HMPREF9374_0031	9.129e-08	55.0	COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,4HR9S@91061|Bacilli	91061|Bacilli	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS2_k127_3329113_3	1379698.RBG1_1C00001G0798	2.617e-109	382.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
GDHHQS2_k127_3329113_6	861299.J421_4437	5.602e-20	94.0	COG4970@1|root,COG4970@2|Bacteria,1ZU5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Tfp pilus assembly protein FimT	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3329113_0	1379270.AUXF01000001_gene2562	1.672e-181	577.0	COG0513@1|root,COG0513@2|Bacteria,1ZSX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS2_k127_3329113_5	861299.J421_4443	2.441e-60	219.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GDHHQS2_k127_3329113_4	1379270.AUXF01000001_gene2561	1.593e-104	352.0	2EW3S@1|root,33PH0@2|Bacteria,1ZTQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3457888_0	861299.J421_3778	9.862e-225	711.0	COG1132@1|root,COG1132@2|Bacteria,1ZSZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_3457888_2	861299.J421_3777	1.491e-96	323.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS2_k127_3457888_6	1379270.AUXF01000003_gene3675	3.319e-13	74.0	2CFMP@1|root,2ZEHG@2|Bacteria,1ZU7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3457888_3	234267.Acid_5343	3.956e-71	248.0	COG4430@1|root,COG4430@2|Bacteria,3Y88Z@57723|Acidobacteria	57723|Acidobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS2_k127_3457888_1	379066.GAU_2123	2.471e-176	560.0	COG3185@1|root,COG3185@2|Bacteria,1ZT62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
GDHHQS2_k127_3457888_4	379066.GAU_2122	3.115e-45	165.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS2_k127_3665725_2	379066.GAU_1285	3.018e-09	58.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS2_k127_3665725_1	215803.DB30_8674	7.858e-109	367.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YUIF@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3665725_0	861299.J421_0859	3.545e-124	405.0	COG0346@1|root,COG0346@2|Bacteria,1ZTUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_3680083_9	1500301.JQMF01000013_gene4515	1.208e-05	48.0	COG2879@1|root,COG2879@2|Bacteria,1N6TY@1224|Proteobacteria,2UJT3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
GDHHQS2_k127_3680083_1	1379270.AUXF01000003_gene3439	1.791e-273	873.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
GDHHQS2_k127_3680083_6	1379270.AUXF01000007_gene855	1.516e-59	215.0	2C4IX@1|root,32RE1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS2_k127_3680083_0	265729.GS18_0219715	9.856e-279	872.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus	91061|Bacilli	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
GDHHQS2_k127_3680083_4	861299.J421_3936	7.041e-133	428.0	COG1409@1|root,COG1409@2|Bacteria,1ZTQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_3680083_5	861299.J421_3935	2.844e-63	224.0	2C421@1|root,33VAH@2|Bacteria,1ZTQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
GDHHQS2_k127_3680083_3	861299.J421_3934	3.335e-208	654.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_3680083_7	1207076.ALAT01000225_gene700	3.943e-17	90.0	COG0467@1|root,COG0467@2|Bacteria,1RK1W@1224|Proteobacteria,1T9X6@1236|Gammaproteobacteria,1Z3R0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS
GDHHQS2_k127_3680083_2	861299.J421_0318	4.302e-232	749.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_3685314_3	861299.J421_3454	4.346e-34	136.0	COG2172@1|root,COG2172@2|Bacteria,1ZU34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS2_k127_3685314_0	861299.J421_3453	2.488e-166	540.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS2_k127_3685314_1	379066.GAU_1882	3.614e-80	275.0	COG0030@1|root,COG0030@2|Bacteria,1ZT2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS2_k127_3685314_2	379066.GAU_1881	8.895e-77	263.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS2_k127_3685314_4	1168034.FH5T_12350	6.739e-25	111.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,2FRKB@200643|Bacteroidia	976|Bacteroidetes	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
GDHHQS2_k127_3691494_64	861299.J421_2579	3.024e-05	47.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS2_k127_3691494_39	861299.J421_2580	1.249e-64	227.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS2_k127_3691494_26	861299.J421_2581	3.62e-98	327.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GDHHQS2_k127_3691494_62	379066.GAU_0637	7.104e-07	57.0	29FAB@1|root,3027Z@2|Bacteria,1ZUYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_1	861299.J421_2582	1.52e-277	866.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
GDHHQS2_k127_3691494_2	861299.J421_2583	2.637e-210	680.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_3691494_41	861299.J421_2584	2.582e-61	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GDHHQS2_k127_3691494_44	335543.Sfum_0374	2.844e-52	194.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MRJB@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_3691494_52	861299.J421_0320	3.469e-32	131.0	2DKY3@1|root,32UFX@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_3691494_13	211165.AJLN01000116_gene3438	2.593e-145	470.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_3691494_16	306281.AJLK01000062_gene4979	1.052e-135	439.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria,1JK84@1189|Stigonemataceae	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_3691494_40	323097.Nham_3038	5.775e-63	220.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,2U5TI@28211|Alphaproteobacteria,3K6DR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GDHHQS2_k127_3691494_60	1033734.CAET01000016_gene4084	6.77e-14	83.0	COG4641@1|root,COG4641@2|Bacteria,1TRY6@1239|Firmicutes,4HJAS@91061|Bacilli,1ZARJ@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,LysM
GDHHQS2_k127_3691494_19	861299.J421_2586	1.972e-127	413.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS2_k127_3691494_17	861299.J421_2587	3.01e-128	415.0	COG1173@1|root,COG1173@2|Bacteria,1ZT0U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS2_k127_3691494_18	861299.J421_2864	6.94e-128	421.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
GDHHQS2_k127_3691494_53	861299.J421_0429	2.925e-30	128.0	294MB@1|root,2ZS0S@2|Bacteria,1ZU7M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_33	365046.Rta_15000	1.294e-79	274.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GDHHQS2_k127_3691494_55	861299.J421_0551	4.7e-30	126.0	2DNQD@1|root,32YJR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
GDHHQS2_k127_3691494_49	1267533.KB906733_gene2915	6.121e-40	151.0	COG0346@1|root,COG0346@2|Bacteria,3Y7XQ@57723|Acidobacteria,2JMYD@204432|Acidobacteriia	204432|Acidobacteriia	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_9	861299.J421_2590	3.001e-165	529.0	COG0162@1|root,COG0162@2|Bacteria,1ZT43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS2_k127_3691494_0	379066.GAU_0644	1.369e-282	889.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS2_k127_3691494_15	861299.J421_2593	1.92e-136	448.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_3691494_25	861299.J421_2213	8.322e-106	358.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_2213|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_21	868131.MSWAN_2422	1.881e-114	378.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23NNK@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_3691494_27	861299.J421_2594	3.943e-95	321.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS2_k127_3691494_42	861299.J421_2595	4.025e-61	217.0	2F73W@1|root,33ZJG@2|Bacteria,1ZTT7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_24	861299.J421_2596	8.272e-107	362.0	2EW4E@1|root,33PHK@2|Bacteria,1ZT53@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_5	1379270.AUXF01000004_gene3232	1.317e-184	587.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_3691494_22	1379270.AUXF01000004_gene3229	3.395e-113	379.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_3691494_10	861299.J421_2605	1.544e-161	530.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GDHHQS2_k127_3691494_38	861299.J421_2606	2.288e-65	231.0	COG2094@1|root,COG2094@2|Bacteria,1ZTNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS2_k127_3691494_4	861299.J421_2609	2.315e-193	610.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Beta-eliminating lyase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_3691494_7	861299.J421_2612	6.274e-178	563.0	COG1063@1|root,COG1063@2|Bacteria,1ZSWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_3691494_34	1254432.SCE1572_09415	5.302e-78	276.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS2_k127_3691494_28	378806.STAUR_3780	4.462e-92	314.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria,2YV2D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
GDHHQS2_k127_3691494_63	1379270.AUXF01000004_gene3222	2.073e-05	48.0	2AF2N@1|root,31516@2|Bacteria,1ZV9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_31	861299.J421_2615	1.01e-83	284.0	COG4123@1|root,COG4123@2|Bacteria,1ZTJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_58	1382303.JPOM01000001_gene738	4.044e-17	90.0	COG0745@1|root,COG3920@1|root,COG0745@2|Bacteria,COG3920@2|Bacteria,1NWAF@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	3.1.4.52	ko:K13246	ko05111,map05111	-	R08991	RC00296	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,GerE,HD,HTH_18,HWE_HK,HisKA_2,PAS,PAS_3,PAS_9,Response_reg,SpoIIE,Trans_reg_C
GDHHQS2_k127_3691494_57	399739.Pmen_1563	6.866e-20	98.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,1S7UX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	luxR family	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS2_k127_3691494_47	1131553.JIBI01000023_gene323	1.986e-44	171.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K17071	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,AAA_25,CHAT,HTH_17,MEDS,NB-ARC,TPR_12
GDHHQS2_k127_3691494_37	861299.J421_2616	7.666e-71	248.0	COG0266@1|root,COG0266@2|Bacteria,1ZTMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS2_k127_3691494_6	861299.J421_2617	3.973e-178	565.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS2_k127_3691494_29	861299.J421_2619	3.601e-88	298.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG	-	-	ko:K02030,ko:K06950,ko:K07814,ko:K09749,ko:K16923	-	M00236,M00582	-	-	ko00000,ko00002,ko02000,ko02022	3.A.1.28,3.A.1.3	-	-	GAF_2,GGDEF,HD,HD_5,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_3691494_54	1158318.ATXC01000001_gene861	3.196e-30	127.0	COG0352@1|root,COG0352@2|Bacteria,2G43B@200783|Aquificae	200783|Aquificae	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS2_k127_3691494_23	861299.J421_2620	2.961e-110	370.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS2_k127_3691494_48	379066.GAU_0666	2.051e-42	164.0	COG0816@1|root,COG0816@2|Bacteria,1ZTWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS2_k127_3691494_3	861299.J421_2622	6.198e-204	643.0	COG1158@1|root,COG1158@2|Bacteria,1ZSXH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS2_k127_3691494_45	861299.J421_2623	1.945e-46	181.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD,OmpA
GDHHQS2_k127_3691494_14	1382356.JQMP01000004_gene541	2.902e-138	449.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS2_k127_3691494_51	479434.Sthe_1946	3.55e-33	143.0	COG3288@1|root,COG3288@2|Bacteria,2GBAD@200795|Chloroflexi,27YI1@189775|Thermomicrobia	189775|Thermomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
GDHHQS2_k127_3691494_11	373994.Riv7116_0186	1.321e-155	504.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1HII6@1161|Nostocales	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
GDHHQS2_k127_3691494_30	1121920.AUAU01000013_gene1716	3.873e-84	287.0	COG4313@1|root,COG4313@2|Bacteria,3Y7K3@57723|Acidobacteria	57723|Acidobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_20	1122138.AQUZ01000001_gene1866	2.753e-124	411.0	COG2132@1|root,COG2132@2|Bacteria,2GPUP@201174|Actinobacteria,4DT49@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
GDHHQS2_k127_3691494_32	266117.Rxyl_0084	4.712e-81	293.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria,4CSVK@84995|Rubrobacteria	84995|Rubrobacteria	P	Mediates zinc uptake. May also transport other divalent cations	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3691494_8	861299.J421_1971	1.426e-177	565.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
GDHHQS2_k127_3691494_12	485918.Cpin_4405	9.697e-155	505.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IVAH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
GDHHQS2_k127_3691494_46	1123508.JH636452_gene6965	6.188e-45	166.0	COG0640@1|root,COG0640@2|Bacteria,2IZUJ@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GDHHQS2_k127_3691494_43	639030.JHVA01000001_gene1931	6.731e-56	205.0	COG3832@1|root,COG3832@2|Bacteria,3Y7X4@57723|Acidobacteria,2JNZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_3691494_36	338969.Rfer_4108	4.118e-72	245.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VSAQ@28216|Betaproteobacteria,4AEGJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GDHHQS2_k127_3691494_35	84531.JMTZ01000031_gene109	2.131e-77	269.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,1T116@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_3691494_50	639283.Snov_0503	1.171e-36	147.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,3F0C5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS2_k127_3697390_1	861299.J421_3333	5.745e-73	251.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3697390_4	379066.GAU_1696	5.083e-52	192.0	COG0584@1|root,COG0584@2|Bacteria,1ZTTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS2_k127_3697390_2	861299.J421_3331	5.67e-61	215.0	COG1595@1|root,COG1595@2|Bacteria,1ZTKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_3697390_6	861299.J421_3330	7.44e-08	61.0	2AETF@1|root,314QF@2|Bacteria,1ZU7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_3697390_5	861299.J421_3329	1.336e-21	100.0	297VI@1|root,2ZV24@2|Bacteria,1ZU61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3697390_0	379066.GAU_0522	0.0	1129.0	COG0841@1|root,COG0841@2|Bacteria,1ZT98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_3697390_3	99598.Cal7507_2315	7.604e-53	193.0	COG0845@1|root,COG0845@2|Bacteria,1G49W@1117|Cyanobacteria,1HR9W@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS2_k127_3707503_4	1379270.AUXF01000004_gene3085	6.861e-79	267.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS2_k127_3707503_5	861299.J421_2718	2.42e-72	252.0	COG0457@1|root,COG0457@2|Bacteria,1ZTR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3707503_6	861299.J421_2716	2.93e-71	242.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3707503_3	861299.J421_2715	5.532e-123	404.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_3707503_0	861299.J421_2714	1.753e-266	839.0	COG0272@1|root,COG0272@2|Bacteria,1ZT5Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS2_k127_3707503_11	1379270.AUXF01000004_gene3089	3.398e-27	120.0	COG1719@1|root,COG1719@2|Bacteria,1ZU65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3707503_7	861299.J421_2712	4.193e-71	244.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GDHHQS2_k127_3707503_9	861299.J421_2711	1.32e-56	201.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
GDHHQS2_k127_3707503_2	861299.J421_2710	2.007e-123	399.0	COG0455@1|root,COG0455@2|Bacteria,1ZTAN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS2_k127_3707503_13	379066.GAU_0785	3.182e-19	99.0	2AEY4@1|root,314VZ@2|Bacteria,1ZUUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3707503_1	1379270.AUXF01000004_gene3094	3.4e-262	820.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS2_k127_3707503_10	861299.J421_2706	1.165e-35	143.0	2FCPE@1|root,344SN@2|Bacteria,1ZU2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3707503_8	1379270.AUXF01000004_gene3096	6.793e-57	206.0	COG4221@1|root,COG4221@2|Bacteria,1ZTPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_3707503_12	861299.J421_2704	3.274e-20	90.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS2_k127_3745427_5	1121472.AQWN01000002_gene2268	6.137e-10	61.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,260AE@186807|Peptococcaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
GDHHQS2_k127_3745427_2	861299.J421_2990	1.584e-58	209.0	COG0299@1|root,COG0299@2|Bacteria,1ZTKJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS2_k127_3745427_3	861299.J421_2991	6.695e-45	171.0	COG0241@1|root,COG0241@2|Bacteria,1ZTT8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GDHHQS2_k127_3745427_0	1121430.JMLG01000005_gene718	1.748e-124	414.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS2_k127_3745427_1	861299.J421_2993	6.94e-62	231.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	DUF2141,MipA
GDHHQS2_k127_3745427_4	702437.HMPREF9432_00416	3.442e-10	63.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4H21Q@909932|Negativicutes	909932|Negativicutes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS2_k127_3775730_17	1379270.AUXF01000003_gene3826	2.875e-07	54.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3775730_13	861299.J421_3627	2.552e-66	236.0	COG2010@1|root,COG2010@2|Bacteria,1ZTPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS2_k127_3775730_11	861299.J421_3628	8.595e-71	246.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GDHHQS2_k127_3775730_2	861299.J421_3629	1.505e-249	779.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS2_k127_3775730_0	861299.J421_3630	0.0	1310.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GDHHQS2_k127_3775730_9	861299.J421_3631	1.731e-74	254.0	COG2010@1|root,COG2010@2|Bacteria,1ZTKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS2_k127_3775730_8	861299.J421_3635	1.841e-87	296.0	COG0565@1|root,COG0565@2|Bacteria,1ZT19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	SpoU rRNA Methylase family	-	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS2_k127_3775730_14	479434.Sthe_0634	1.164e-47	178.0	COG5483@1|root,COG5483@2|Bacteria,2G8NZ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS2_k127_3775730_6	861299.J421_2858	1.255e-112	375.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS2_k127_3775730_10	379066.GAU_2047	1.445e-71	248.0	COG0586@1|root,COG0586@2|Bacteria,1ZTJB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS2_k127_3775730_7	379066.GAU_2048	2.238e-101	333.0	COG0605@1|root,COG0605@2|Bacteria,1ZT7S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS2_k127_3775730_1	861299.J421_3647	1.62e-321	994.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GDHHQS2_k127_3775730_12	1297742.A176_03628	1.467e-69	240.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
GDHHQS2_k127_3775730_4	404589.Anae109_3607	2.646e-154	496.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS2_k127_3775730_5	861299.J421_3021	1.602e-149	487.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1ZT0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
GDHHQS2_k127_3775730_3	234267.Acid_4487	1.57e-207	664.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_3786362_9	379066.GAU_3581	1.7e-28	118.0	COG1609@1|root,COG1609@2|Bacteria,1ZTYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_3786362_3	379066.GAU_2691	2.31e-83	293.0	2CCCP@1|root,33QJX@2|Bacteria,1ZTIZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3786362_2	234267.Acid_4499	8.814e-106	354.0	COG0451@1|root,COG0451@2|Bacteria,3Y91Q@57723|Acidobacteria	57723|Acidobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3786362_5	1173027.Mic7113_1687	4.156e-52	206.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria,1H7J1@1150|Oscillatoriales	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
GDHHQS2_k127_3786362_6	378806.STAUR_2193	4.555e-41	156.0	COG3631@1|root,COG3631@2|Bacteria,1NAUM@1224|Proteobacteria,4383T@68525|delta/epsilon subdivisions,2X9WN@28221|Deltaproteobacteria,2YVM6@29|Myxococcales	28221|Deltaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS2_k127_3786362_12	1123073.KB899243_gene729	1.815e-15	81.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1SGZZ@1236|Gammaproteobacteria,1XC0C@135614|Xanthomonadales	135614|Xanthomonadales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS2_k127_3786362_10	84531.JMTZ01000042_gene1168	6.507e-22	101.0	291D5@1|root,2ZP00@2|Bacteria,1PCY6@1224|Proteobacteria,1SY3T@1236|Gammaproteobacteria,1X76U@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3786362_14	243164.DET1552	0.0001275	48.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_3786362_1	861299.J421_4331	1.55e-127	415.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS2_k127_3786362_7	861299.J421_4333	5.52e-37	152.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GDHHQS2_k127_3786362_4	861299.J421_4334	1.218e-65	238.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS2_k127_3786362_8	861299.J421_4335	8.487e-32	136.0	2F1E3@1|root,33UEU@2|Bacteria,1ZTQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3786362_0	861299.J421_4336	5.028e-136	449.0	COG1306@1|root,COG1306@2|Bacteria	2|Bacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS2_k127_3786362_13	1121324.CLIT_20c00250	4.076e-08	57.0	COG2608@1|root,COG2608@2|Bacteria,1VIRN@1239|Firmicutes,25CYU@186801|Clostridia	186801|Clostridia	P	PFAM Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
GDHHQS2_k127_3813321_0	1278073.MYSTI_06593	7.696e-120	409.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,437YB@68525|delta/epsilon subdivisions,2X387@28221|Deltaproteobacteria,2YVXR@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_3813321_2	706587.Desti_5411	3.833e-41	156.0	COG2050@1|root,COG2050@2|Bacteria,1NGFY@1224|Proteobacteria,42UY5@68525|delta/epsilon subdivisions,2WSY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
GDHHQS2_k127_3813321_3	870187.Thini_0382	2.746e-29	121.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales	72273|Thiotrichales	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
GDHHQS2_k127_3813321_1	234267.Acid_7338	8.707e-80	280.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3825073_3	670292.JH26_25465	2.998e-77	263.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,1JV9X@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_3825073_2	215803.DB30_2889	1.821e-101	337.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,43A1M@68525|delta/epsilon subdivisions,2X25R@28221|Deltaproteobacteria,2YUPF@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_3825073_11	1183438.GKIL_2277	8.325e-09	66.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
GDHHQS2_k127_3825073_10	1380391.JIAS01000019_gene1266	8.402e-13	81.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
GDHHQS2_k127_3825073_7	1174504.AJTN02000217_gene3143	2.624e-37	156.0	COG3577@1|root,COG3577@2|Bacteria,1VKN9@1239|Firmicutes	1239|Firmicutes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
GDHHQS2_k127_3825073_6	13035.Dacsa_2599	4.946e-59	209.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GDHHQS2_k127_3825073_4	379066.GAU_2670	2.129e-65	235.0	COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3825073_0	379066.GAU_2120	6.482e-180	578.0	COG1649@1|root,COG1649@2|Bacteria,1ZSWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS2_k127_3825073_12	497965.Cyan7822_0539	0.0004867	48.0	28YS9@1|root,2ZKJQ@2|Bacteria,1GH2X@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3825073_1	754035.Mesau_05451	2.531e-154	497.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS2_k127_3825073_8	497965.Cyan7822_0541	2.438e-26	112.0	COG1873@1|root,COG1873@2|Bacteria,1GEUB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3825073_9	497965.Cyan7822_0542	8.271e-22	99.0	2EM7X@1|root,33EX1@2|Bacteria,1GEMJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3825073_5	448385.sce5973	5e-61	214.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_3832523_9	861299.J421_4342	7.066e-05	46.0	2CCCN@1|root,2ZG14@2|Bacteria,1ZU5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3832523_1	861299.J421_4346	2.825e-180	578.0	COG2239@1|root,COG2239@2|Bacteria,1ZT3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS2_k127_3832523_2	861299.J421_1756	1.403e-164	533.0	COG0624@1|root,COG0624@2|Bacteria,1ZUA4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_3832523_8	365046.Rta_16920	1.845e-19	94.0	2AWDT@1|root,32ZDK@2|Bacteria,1NE1B@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
GDHHQS2_k127_3832523_0	404589.Anae109_2419	1.415e-205	662.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_3832523_5	861299.J421_4349	2.515e-48	181.0	COG3346@1|root,COG3346@2|Bacteria,1ZTTS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SURF1 family	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
GDHHQS2_k127_3832523_7	1116472.MGMO_55c00340	5.822e-20	94.0	2B0DW@1|root,31SR8@2|Bacteria,1RHKN@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
GDHHQS2_k127_3832523_4	204669.Acid345_1150	1.013e-65	231.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3832523_3	861299.J421_4352	5.488e-119	388.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS2_k127_3832523_6	886293.Sinac_0383	1.818e-46	175.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS2_k127_3841153_0	861299.J421_3412	1.742e-83	280.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS2_k127_3841153_2	861299.J421_3413	1.943e-60	210.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS2_k127_3841153_1	1379270.AUXF01000006_gene117	3.63e-70	241.0	COG0102@1|root,COG0102@2|Bacteria,1ZTIS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS2_k127_3841153_4	861299.J421_3415	1.545e-49	185.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS2_k127_3841153_3	861299.J421_3416	1.387e-54	197.0	COG2265@1|root,COG2265@2|Bacteria,1ZSPC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
GDHHQS2_k127_3850557_9	1379270.AUXF01000006_gene233	1.345e-63	227.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS2_k127_3850557_1	861299.J421_3292	3.387e-239	744.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS2_k127_3850557_7	861299.J421_3293	9.808e-102	340.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS2_k127_3850557_6	1379270.AUXF01000006_gene230	2.906e-106	348.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS2_k127_3850557_16	497964.CfE428DRAFT_4575	8.541e-14	77.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS2_k127_3850557_8	379066.GAU_1663	8.619e-100	330.0	COG0717@1|root,COG0717@2|Bacteria,1ZSN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS2_k127_3850557_5	861299.J421_3298	1.964e-120	392.0	COG0479@1|root,COG0479@2|Bacteria,1ZT02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS2_k127_3850557_0	1128421.JAGA01000003_gene2923	0.0	1067.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_3850557_10	861299.J421_3300	3.534e-62	220.0	2CAZH@1|root,2Z7RU@2|Bacteria,1ZTQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
GDHHQS2_k127_3850557_3	861299.J421_3301	7.009e-165	523.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS2_k127_3850557_4	1379270.AUXF01000006_gene220	8.71e-144	462.0	COG2896@1|root,COG2896@2|Bacteria,1ZSMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GDHHQS2_k127_3850557_12	1379270.AUXF01000006_gene219	3.196e-40	153.0	COG0314@1|root,COG0314@2|Bacteria,1ZU08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
GDHHQS2_k127_3850557_15	861299.J421_3304	1.558e-18	87.0	COG1977@1|root,COG1977@2|Bacteria,1ZU69@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_3850557_11	861299.J421_3305	4.665e-50	180.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS2_k127_3850557_2	861299.J421_3306	5.065e-180	574.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS2_k127_3850557_14	379066.GAU_1676	6.841e-32	128.0	COG1314@1|root,COG1314@2|Bacteria,1ZTZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS2_k127_3850557_13	861299.J421_3308	2.586e-35	138.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS2_k127_3883106_1	861299.J421_2569	1.438e-169	538.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS2_k127_3883106_8	379066.GAU_0626	2.702e-35	137.0	COG1862@1|root,COG1862@2|Bacteria,1ZU5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS2_k127_3883106_6	861299.J421_2567	6.822e-63	224.0	COG0242@1|root,COG0242@2|Bacteria,1ZTPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS2_k127_3883106_3	861299.J421_2566	6.642e-107	355.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS2_k127_3883106_9	1382358.JHVN01000015_gene655	1.902e-32	137.0	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,21WTY@150247|Anoxybacillus	91061|Bacilli	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3,5.3.99.10	ko:K00788,ko:K10810	ko00730,ko01100,map00730,map01100	M00127	R03223,R09977,R10712	RC00224,RC02766,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	TMP-TENI
GDHHQS2_k127_3883106_11	1336208.JADY01000002_gene343	3.662e-08	64.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria	1224|Proteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_3883106_4	243231.GSU0588	6.491e-92	309.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS2_k127_3883106_0	1379270.AUXF01000004_gene3261	1.073e-172	558.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
GDHHQS2_k127_3883106_10	1125718.HMPREF1318_0369	2.006e-24	113.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3IX@85005|Actinomycetales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS2_k127_3883106_5	861299.J421_2563	1.125e-87	304.0	COG0036@1|root,COG0036@2|Bacteria,1ZSP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS2_k127_3883106_7	379066.GAU_0620	1.684e-57	205.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_3883106_2	861299.J421_2560	8.109e-156	497.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS2_k127_3891019_0	861299.J421_3334	1.121e-173	554.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	861299.J421_3334|-	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3891019_1	861299.J421_3333	1.098e-171	542.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3898907_5	861299.J421_3261	1.311e-81	276.0	COG0512@1|root,COG0512@2|Bacteria,1ZTK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS2_k127_3898907_2	861299.J421_3262	9.685e-150	479.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_3898907_7	861299.J421_3263	1.337e-42	163.0	COG0586@1|root,COG0586@2|Bacteria,1ZTVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_3898907_6	379066.GAU_1631	4.396e-60	214.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GDHHQS2_k127_3898907_0	861299.J421_3265	2.268e-190	600.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS2_k127_3898907_3	861299.J421_3266	1.304e-119	389.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS2_k127_3898907_1	1379270.AUXF01000006_gene256	9.598e-182	576.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS2_k127_3898907_4	1379270.AUXF01000006_gene255	1.204e-108	356.0	COG0304@1|root,COG0304@2|Bacteria,1ZSPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_3916097_3	379066.GAU_1623	1.011e-78	265.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS2_k127_3916097_1	1379270.AUXF01000006_gene268	2.336e-127	417.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
GDHHQS2_k127_3916097_5	861299.J421_3253	2.823e-42	162.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
GDHHQS2_k127_3916097_2	861299.J421_3252	4.239e-108	367.0	2F01D@1|root,33T57@2|Bacteria,1ZTGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3916097_0	861299.J421_3251	2.341e-164	529.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
GDHHQS2_k127_3916097_4	861299.J421_3250	7.249e-73	250.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GDHHQS2_k127_3933815_2	251221.35214309	6.017e-88	315.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS2_k127_3933815_6	861299.J421_5622	8.145e-65	241.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5622|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3933815_3	1267533.KB906735_gene4691	3.314e-82	286.0	COG3186@1|root,COG3186@2|Bacteria,3Y3K5@57723|Acidobacteria,2JHN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Biopterin-dependent aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
GDHHQS2_k127_3933815_9	1379270.AUXF01000002_gene1799	7.34e-35	139.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS2_k127_3933815_7	861299.J421_1839	3.819e-57	220.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS2_k127_3933815_0	1379270.AUXF01000003_gene3738	2.421e-251	803.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_3933815_4	714943.Mucpa_5289	3.248e-78	276.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1IP20@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3933815_5	861299.J421_3686	1.367e-65	236.0	COG2755@1|root,COG2755@2|Bacteria,1ZTN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_3933815_1	861299.J421_3685	2.473e-102	336.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS2_k127_3933815_8	1379270.AUXF01000003_gene3745	1.421e-50	185.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_3937140_4	379066.GAU_1544	1.741e-127	417.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS2_k127_3937140_0	861299.J421_3175	8.785e-179	568.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS2_k127_3937140_10	861299.J421_3174	4.689e-21	100.0	2FES0@1|root,346R1@2|Bacteria,1ZU3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3937140_9	861299.J421_3172	3.96e-51	186.0	COG0745@1|root,COG0745@2|Bacteria,1ZU0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_3937140_2	861299.J421_3171	1.032e-135	440.0	COG0836@1|root,COG0836@2|Bacteria,1ZT5Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_3937140_3	861299.J421_3170	1.567e-133	438.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
GDHHQS2_k127_3937140_7	861299.J421_3169	8.266e-66	234.0	COG1235@1|root,COG1235@2|Bacteria,1ZTN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS2_k127_3937140_8	861299.J421_2234	2.73e-58	208.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
GDHHQS2_k127_3937140_5	861299.J421_1517	9.091e-68	246.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3937140_1	1500890.JQNL01000001_gene1099	1.49e-159	513.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X4AH@135614|Xanthomonadales	135614|Xanthomonadales	E	cystathionine	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_3937140_6	1384056.N787_12445	1.304e-66	239.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RXCB@1236|Gammaproteobacteria,1X4WJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the AB hydrolase superfamily. MetX family	metXS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GDHHQS2_k127_3941548_3	1379270.AUXF01000001_gene2535	2.359e-243	758.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_3941548_1	861299.J421_4453	9.041e-260	816.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1ZTC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS2_k127_3941548_2	861299.J421_4452	3.837e-256	812.0	COG0744@1|root,COG0744@2|Bacteria,1ZSRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS2_k127_3941548_0	1379270.AUXF01000001_gene2553	0.0	1312.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_3941548_4	861299.J421_4449	3.016e-182	590.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_3941548_5	1118054.CAGW01000082_gene3065	3.474e-76	270.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,26T8W@186822|Paenibacillaceae	91061|Bacilli	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS2_k127_3950843_3	1267533.KB906737_gene1757	3.929e-32	131.0	COG1680@1|root,COG1680@2|Bacteria,3Y889@57723|Acidobacteria,2JNBM@204432|Acidobacteriia	204432|Acidobacteriia	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_3950843_0	1379270.AUXF01000002_gene1241	2.058e-251	797.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZTK4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
GDHHQS2_k127_3950843_1	1313421.JHBV01000020_gene5241	5.019e-43	163.0	COG2318@1|root,COG2318@2|Bacteria,4P4A6@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_3950843_2	1123248.KB893354_gene2294	5.851e-42	159.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1IRU4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS2_k127_3950999_0	1379270.AUXF01000004_gene3177	7.639e-121	391.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS2_k127_3950999_1	379066.GAU_0713	6.568e-73	255.0	COG2207@1|root,COG2207@2|Bacteria,1ZUCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_3950999_2	861299.J421_2627	4.652e-32	125.0	COG0056@1|root,COG0056@2|Bacteria,1ZSNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS2_k127_4005968_1	1089547.KB913013_gene73	6.438e-48	180.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS2_k127_4005968_0	861299.J421_5977	6.713e-117	388.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS2_k127_401663_1	945713.IALB_3087	5.423e-117	385.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
GDHHQS2_k127_401663_0	1242864.D187_000199	3.976e-210	675.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
GDHHQS2_k127_403523_0	1038867.AXAY01000062_gene4409	3.141e-95	320.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,2UEXR@28211|Alphaproteobacteria,3K36S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
GDHHQS2_k127_403523_3	1121920.AUAU01000009_gene1868	5.19e-18	93.0	COG0454@1|root,COG0456@2|Bacteria,3Y5Y6@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_403523_1	861299.J421_0325	8.717e-95	320.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_403523_2	861299.J421_2231	5.748e-71	244.0	COG3568@1|root,COG3568@2|Bacteria,1ZV66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS2_k127_4127649_9	861299.J421_6223	8.315e-58	207.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4127649_7	861299.J421_0340	2.232e-77	267.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
GDHHQS2_k127_4127649_13	861299.J421_3379	2.551e-24	106.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
GDHHQS2_k127_4127649_1	1452718.JBOY01000054_gene1977	1.689e-157	516.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
GDHHQS2_k127_4127649_15	1379270.AUXF01000003_gene3388	7.099e-20	94.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_4127649_3	861299.J421_1003	3.491e-116	393.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_4127649_2	596151.DesfrDRAFT_3682	1.068e-156	514.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria,2MARP@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
GDHHQS2_k127_4127649_4	1267535.KB906767_gene2627	1.435e-108	368.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS2_k127_4127649_10	1123393.KB891316_gene2013	1.715e-38	151.0	COG0025@1|root,COG0025@2|Bacteria,1QTZ5@1224|Proteobacteria,2WGIC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
GDHHQS2_k127_4127649_14	1386089.N865_20590	2.699e-21	100.0	2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4FHK1@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4127649_5	479434.Sthe_0342	2.781e-102	339.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS2_k127_4127649_6	479434.Sthe_0341	2.061e-96	318.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_4127649_0	204669.Acid345_1748	1.154e-202	645.0	COG0492@1|root,COG0492@2|Bacteria,3Y3SH@57723|Acidobacteria,2JI51@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_4127649_11	861299.J421_2331	1.19e-34	146.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667,HlyD_3
GDHHQS2_k127_4127649_12	861299.J421_3138	4.874e-34	139.0	2F4AY@1|root,33YV0@2|Bacteria,1ZU13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4127649_8	861299.J421_1786	3.132e-59	217.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS2_k127_4127649_16	1415778.JQMM01000001_gene2084	0.0007807	45.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_413925_0	1382306.JNIM01000001_gene665	0.0	1394.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS2_k127_413925_1	1379270.AUXF01000004_gene3330	1.09e-294	916.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS2_k127_413925_3	760192.Halhy_4503	6.441e-29	123.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS2_k127_413925_4	45157.CMH050CT	2.108e-28	118.0	COG2138@1|root,2RXIW@2759|Eukaryota	2759|Eukaryota	S	sirohydrochlorin cobaltochelatase activity	-	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
GDHHQS2_k127_413925_2	379066.GAU_0555	1.793e-117	385.0	COG1960@1|root,COG1960@2|Bacteria,1ZT6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_4142944_8	861299.J421_2639	7.714e-80	281.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	2.6.1.85	ko:K13950,ko:K21025	ko00790,ko02025,map00790,map02025	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
GDHHQS2_k127_4142944_11	861299.J421_2640	6.304e-59	220.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
GDHHQS2_k127_4142944_4	861299.J421_2641	9.104e-133	437.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
GDHHQS2_k127_4142944_12	861299.J421_2642	6.793e-57	206.0	COG1651@1|root,COG1651@2|Bacteria,1ZTVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS2_k127_4142944_9	861299.J421_2643	4.866e-72	252.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GDHHQS2_k127_4142944_7	861299.J421_2644	5.269e-84	291.0	COG1708@1|root,COG1708@2|Bacteria,1ZTN5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4142944_10	861299.J421_2645	8.666e-61	215.0	COG1704@1|root,COG1704@2|Bacteria,1ZTQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS2_k127_4142944_2	1297742.A176_02902	3.26e-207	679.0	COG4206@1|root,COG4206@2|Bacteria,1QXUW@1224|Proteobacteria,43C7J@68525|delta/epsilon subdivisions,2X7HV@28221|Deltaproteobacteria,2YU5W@29|Myxococcales	28221|Deltaproteobacteria	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS2_k127_4142944_13	379066.GAU_1463	3.609e-55	211.0	28II1@1|root,2Z8J7@2|Bacteria,1ZUX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
GDHHQS2_k127_4142944_0	861299.J421_0487	0.0	1031.0	COG2936@1|root,COG2936@2|Bacteria,1ZUE2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_4142944_14	1379270.AUXF01000001_gene2088	2.118e-07	59.0	2DDI2@1|root,2ZI6I@2|Bacteria,1ZVAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4142944_1	861299.J421_2653	4.926e-221	695.0	COG0143@1|root,COG0143@2|Bacteria,1ZTDB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
GDHHQS2_k127_4142944_5	1379270.AUXF01000004_gene3143	8.178e-132	429.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS2_k127_4142944_3	861299.J421_2655	1.622e-157	501.0	COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
GDHHQS2_k127_4142944_6	861299.J421_2656	1.401e-89	301.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GDHHQS2_k127_4201958_2	1379270.AUXF01000002_gene1431	3.386e-122	403.0	COG4992@1|root,COG4992@2|Bacteria,1ZTEJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_4201958_4	379066.GAU_0158	2.709e-69	243.0	COG0548@1|root,COG0548@2|Bacteria,1ZTJI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_4201958_3	861299.J421_1328	1.052e-120	395.0	COG0002@1|root,COG0002@2|Bacteria,1ZSV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_4201958_5	861299.J421_1325	2.46e-54	195.0	COG1438@1|root,COG1438@2|Bacteria,1ZU02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
GDHHQS2_k127_4201958_0	861299.J421_1323	5.295e-214	670.0	COG0137@1|root,COG0137@2|Bacteria,1ZTYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS2_k127_4201958_1	861299.J421_1322	4.52e-203	640.0	COG0165@1|root,COG0165@2|Bacteria,1ZSM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS2_k127_4264614_1	861299.J421_3258	8.523e-76	260.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS2_k127_4264614_0	861299.J421_3257	1.191e-289	897.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS2_k127_4264614_2	1379270.AUXF01000006_gene266	9.041e-67	229.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS2_k127_4350322_4	289376.THEYE_A2098	4.012e-26	109.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS2_k127_4350322_0	379066.GAU_1164	3.155e-168	543.0	COG0606@1|root,COG0606@2|Bacteria,1ZSXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS2_k127_4350322_7	1379698.RBG1_1C00001G0272	6.949e-16	85.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF2505
GDHHQS2_k127_4350322_2	1254432.SCE1572_21210	9.803e-49	185.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4350322_1	234267.Acid_5756	2.086e-60	223.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_4350322_3	861299.J421_2916	4.426e-47	177.0	28R18@1|root,2ZDFV@2|Bacteria,1ZU2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4350322_5	861299.J421_2917	2.733e-25	112.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_4471351_10	861299.J421_4471	4.168e-117	378.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_4471351_21	861299.J421_4473	2.932e-07	63.0	2F33T@1|root,33VYR@2|Bacteria,1ZTS4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
GDHHQS2_k127_4471351_12	1128421.JAGA01000004_gene2517	5.509e-107	355.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS2_k127_4471351_18	861299.J421_4479	2.593e-28	117.0	2FCBU@1|root,344FF@2|Bacteria,1ZU39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4471351_19	861299.J421_1124	3.386e-17	84.0	2EPV2@1|root,33HFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4471351_14	861299.J421_4482	4.637e-48	174.0	COG3411@1|root,COG3411@2|Bacteria,1ZU0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4471351_5	861299.J421_4484	3.311e-146	469.0	COG2897@1|root,COG2897@2|Bacteria,1ZTF6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS2_k127_4471351_16	861299.J421_4485	4.896e-32	140.0	COG1765@1|root,COG1765@2|Bacteria,1ZTV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS2_k127_4471351_11	379066.GAU_2851	4.161e-110	364.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
GDHHQS2_k127_4471351_17	861299.J421_4532	2.747e-31	128.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4471351_6	861299.J421_4533	3.982e-140	453.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS2_k127_4471351_2	861299.J421_4536	1.289e-166	541.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_4471351_0	379066.GAU_2856	4.371e-266	842.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GDHHQS2_k127_4471351_1	379066.GAU_2857	1.494e-204	643.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_4471351_9	861299.J421_1546	1.08e-118	394.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1ZTKM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18
GDHHQS2_k127_4471351_15	1267534.KB906756_gene299	4.268e-42	163.0	29PQU@1|root,30AP1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
GDHHQS2_k127_4471351_4	483219.LILAB_09765	1.333e-153	501.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GDHHQS2_k127_4471351_13	861299.J421_0057	1.202e-65	228.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS2_k127_4471351_3	251221.35211608	1.148e-163	527.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS2_k127_4471351_7	861299.J421_0058	1.284e-136	443.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_4471351_8	861299.J421_0060	2.206e-124	414.0	COG1524@1|root,COG1524@2|Bacteria,1ZT33@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_448281_0	379066.GAU_2360	1.253e-146	484.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_448281_1	1191523.MROS_1073	3.318e-06	59.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K09476	ko01501,ko02020,map01501,map02020	M00746	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.1.1.1	-	-	Porin_4
GDHHQS2_k127_45560_1	1449065.JMLL01000014_gene3356	1.256e-126	409.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,43JXC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
GDHHQS2_k127_45560_2	313606.M23134_01907	1.748e-70	250.0	COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes,47PRW@768503|Cytophagia	976|Bacteroidetes	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N,TPR_2
GDHHQS2_k127_45560_0	861299.J421_5944	6.686e-216	674.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_4558457_11	511051.CSE_08200	7.793e-24	105.0	COG0295@1|root,COG0295@2|Bacteria	2|Bacteria	F	cytidine deaminase activity	cdd	-	2.4.2.2,3.5.4.5	ko:K00756,ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01570,R01876,R01878,R02296,R02484,R02485,R08221	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
GDHHQS2_k127_4558457_3	861299.J421_3094	6.426e-178	565.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
GDHHQS2_k127_4558457_10	379066.GAU_1449	2.931e-76	269.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS2_k127_4558457_7	861299.J421_3092	3.294e-102	342.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
GDHHQS2_k127_4558457_8	1185876.BN8_06034	4.102e-91	318.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,47N0P@768503|Cytophagia	976|Bacteroidetes	O	proteinase inhibitor I4 serpin	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS2_k127_4558457_1	1379270.AUXF01000005_gene701	3.112e-208	664.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_4558457_4	1392498.JQLH01000001_gene912	3.595e-132	436.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia,2PH19@252356|Maribacter	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_4558457_6	861299.J421_3088	2.617e-113	384.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_4558457_0	861299.J421_3084	0.0	1027.0	COG1200@1|root,COG1200@2|Bacteria,1ZT3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS2_k127_4558457_5	861299.J421_3083	3.93e-122	399.0	COG0552@1|root,COG0552@2|Bacteria,1ZTBT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS2_k127_4558457_9	861299.J421_3081	3.922e-83	288.0	COG0739@1|root,COG0739@2|Bacteria,1ZSUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_4558457_2	861299.J421_3080	2.072e-191	604.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS2_k127_4610556_22	1123508.JH636441_gene3757	2.438e-14	74.0	COG4877@1|root,COG4877@2|Bacteria,2J4M8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4610556_14	379066.GAU_3596	2.02e-101	338.0	COG0330@1|root,COG0330@2|Bacteria,1ZUIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_4610556_1	861299.J421_3751	0.0	1028.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
GDHHQS2_k127_4610556_12	861299.J421_3752	9.243e-113	373.0	COG0859@1|root,COG0859@2|Bacteria,1ZSYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS2_k127_4610556_7	861299.J421_3753	3.013e-148	478.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_4610556_8	1379270.AUXF01000003_gene3691	3.234e-134	434.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4610556_11	861299.J421_3755	2.476e-117	385.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4610556_19	1379270.AUXF01000003_gene3689	5.734e-48	179.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4610556_21	1379270.AUXF01000003_gene3688	8.664e-19	90.0	298RJ@1|root,2ZVVV@2|Bacteria,1ZU7B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Molydop_binding
GDHHQS2_k127_4610556_5	861299.J421_3758	7.62e-167	534.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_4610556_16	861299.J421_3759	1.386e-86	294.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
GDHHQS2_k127_4610556_15	861299.J421_3760	6.966e-92	309.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
GDHHQS2_k127_4610556_13	1379270.AUXF01000003_gene3684	6.678e-112	383.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_4610556_6	1101192.KB910516_gene93	8.124e-160	517.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,1JT2Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Acts as a magnesium transporter	mgtE	GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS2_k127_4610556_18	1379698.RBG1_1C00001G0109	8.905e-66	235.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
GDHHQS2_k127_4610556_17	247490.KSU1_D0783	1.457e-86	295.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
GDHHQS2_k127_4610556_10	247490.KSU1_D0782	5.592e-119	398.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4610556_0	861299.J421_3771	0.0	1183.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1ZT01@142182|Gemmatimonadetes	2|Bacteria	C	Phosphate acetyl/butaryl transferase	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
GDHHQS2_k127_4610556_2	379066.GAU_2166	5.082e-276	856.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
GDHHQS2_k127_4610556_4	861299.J421_3775	2.918e-172	552.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
GDHHQS2_k127_4610556_20	886293.Sinac_4724	4.53e-33	134.0	COG2340@1|root,COG2340@2|Bacteria,2J0UH@203682|Planctomycetes	203682|Planctomycetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GDHHQS2_k127_4610556_3	379066.GAU_2126	2.632e-258	815.0	COG0365@1|root,COG0365@2|Bacteria,1ZSSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS2_k127_4610556_9	1379270.AUXF01000003_gene3729	1.063e-119	385.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS2_k127_4630100_12	1379270.AUXF01000005_gene670	7.641e-13	74.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS2_k127_4630100_11	383372.Rcas_1731	2.241e-34	141.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS2_k127_4630100_9	861299.J421_3059	1.648e-81	275.0	COG1100@1|root,COG1100@2|Bacteria,1ZTK3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
GDHHQS2_k127_4630100_8	1379270.AUXF01000005_gene674	5.559e-88	306.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
GDHHQS2_k127_4630100_7	861299.J421_3062	7.611e-89	304.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GDHHQS2_k127_4630100_5	1379270.AUXF01000005_gene676	5.65e-104	349.0	COG2201@1|root,COG2201@2|Bacteria,1ZUFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS2_k127_4630100_3	1248916.ANFY01000005_gene2779	2.067e-156	501.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2K275@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_4630100_13	861299.J421_3066	1.766e-10	65.0	2DENK@1|root,2ZNKE@2|Bacteria,1ZV91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4630100_4	861299.J421_3067	1.614e-104	361.0	COG0457@1|root,COG0457@2|Bacteria,1ZSXZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4630100_6	379066.GAU_1420	1.988e-103	344.0	COG0275@1|root,COG0275@2|Bacteria,1ZT4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS2_k127_4630100_0	861299.J421_3070	6.52e-186	605.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GDHHQS2_k127_4630100_1	861299.J421_3071	1.404e-182	583.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_4630100_2	861299.J421_3072	1.168e-173	556.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_4630100_10	1379270.AUXF01000005_gene687	5.771e-39	149.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
GDHHQS2_k127_4631512_2	861299.J421_2696	3.355e-52	187.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GDHHQS2_k127_4631512_3	379066.GAU_0773	4.093e-25	117.0	2FF43@1|root,34729@2|Bacteria,1ZTX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4631512_0	861299.J421_2694	3e-323	998.0	COG0433@1|root,COG0433@2|Bacteria,1ZURZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_4631512_1	861299.J421_2693	3.789e-91	310.0	COG2380@1|root,COG2380@2|Bacteria,1ZUZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4631512_4	861299.J421_2691	6.495e-25	104.0	COG1522@1|root,COG1522@2|Bacteria,1ZU0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS2_k127_4646562_0	378806.STAUR_8168	8.249e-281	893.0	COG1629@1|root,COG4771@2|Bacteria,1QX6X@1224|Proteobacteria,43BZN@68525|delta/epsilon subdivisions,2X7AF@28221|Deltaproteobacteria,2Z3EM@29|Myxococcales	28221|Deltaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
GDHHQS2_k127_4646562_1	246197.MXAN_4747	1.071e-133	441.0	COG3193@1|root,COG3193@2|Bacteria,1QX6Y@1224|Proteobacteria,43BZP@68525|delta/epsilon subdivisions,2X7AG@28221|Deltaproteobacteria,2YU0D@29|Myxococcales	28221|Deltaproteobacteria	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
GDHHQS2_k127_4651866_3	379066.GAU_2720	0.0006651	43.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
GDHHQS2_k127_4651866_0	379066.GAU_2721	1.51e-88	320.0	COG0553@1|root,COG0553@2|Bacteria,1ZUB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
GDHHQS2_k127_4651866_1	861299.J421_3651	6.823e-45	172.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	yqjI	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_4651866_2	1173022.Cri9333_2515	4.079e-11	67.0	COG2199@1|root,COG2203@1|root,COG3290@1|root,COG3300@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3300@2|Bacteria,1GQQT@1117|Cyanobacteria,1HHYP@1150|Oscillatoriales	1117|Cyanobacteria	T	SPTR Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) (Modular protein)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
GDHHQS2_k127_4664847_4	861299.J421_1204	2.551e-18	89.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS2_k127_4664847_3	1122605.KB893648_gene3540	9.472e-33	135.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
GDHHQS2_k127_4664847_0	379066.GAU_0818	2.397e-207	658.0	COG0554@1|root,COG0554@2|Bacteria,1ZTX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_4664847_1	861299.J421_2733	2.657e-123	405.0	COG3569@1|root,COG3569@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	MA20_25110	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
GDHHQS2_k127_4664847_2	1379270.AUXF01000004_gene3079	8.034e-56	198.0	COG1024@1|root,COG1024@2|Bacteria,1ZT76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS2_k127_4672809_16	861299.J421_1140	1.362e-49	183.0	28JRZ@1|root,2Z9HI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GDHHQS2_k127_4672809_14	861299.J421_0700	4.987e-58	207.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55,5.5.1.4	ko:K01858,ko:K03207,ko:K03574	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
GDHHQS2_k127_4672809_3	379066.GAU_0170	9.549e-146	471.0	COG0823@1|root,COG0823@2|Bacteria,1ZTFG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_4672809_1	861299.J421_1048	8.976e-302	951.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS2_k127_4672809_12	1379270.AUXF01000003_gene3470	7.292e-65	236.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS2_k127_4672809_20	1123261.AXDW01000007_gene2155	8.442e-14	85.0	COG1018@1|root,COG2373@1|root,COG4932@1|root,COG1018@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,1QW47@1224|Proteobacteria,1RQU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
GDHHQS2_k127_4672809_18	1232410.KI421422_gene2088	3.275e-45	173.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS2_k127_4672809_2	649747.HMPREF0083_01283	2.027e-174	557.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,26QU4@186822|Paenibacillaceae	91061|Bacilli	EG	Gluconate	gntP	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
GDHHQS2_k127_4672809_15	296591.Bpro_3525	2.327e-54	200.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,2VSY0@28216|Betaproteobacteria,4AEM1@80864|Comamonadaceae	28216|Betaproteobacteria	F	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,SKI
GDHHQS2_k127_4672809_13	861299.J421_3139	1.253e-64	225.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
GDHHQS2_k127_4672809_0	379066.GAU_1492	0.0	1296.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS2_k127_4672809_17	1379270.AUXF01000005_gene746	1.005e-46	173.0	COG2866@1|root,COG2866@2|Bacteria,1ZTUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4672809_5	1121468.AUBR01000016_gene2302	2.697e-110	380.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,42F9D@68295|Thermoanaerobacterales	186801|Clostridia	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS2_k127_4672809_8	861299.J421_3135	1.421e-83	284.0	COG1381@1|root,COG1381@2|Bacteria,1ZTHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS2_k127_4672809_4	861299.J421_3134	1.196e-143	480.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_4672809_7	861299.J421_3133	6.207e-90	308.0	COG1120@1|root,COG1120@2|Bacteria,1ZTB9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS2_k127_4672809_6	861299.J421_3132	3.714e-106	354.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS2_k127_4672809_9	861299.J421_3131	1.337e-80	278.0	COG0614@1|root,COG0614@2|Bacteria,1ZTIM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS2_k127_4672809_10	861299.J421_3130	5.455e-71	251.0	COG2010@1|root,COG2010@2|Bacteria,1ZT9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4672809_11	861299.J421_3129	3.396e-65	226.0	COG1259@1|root,COG1259@2|Bacteria,1ZTKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS2_k127_4672809_21	379066.GAU_1484	1.838e-11	64.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS2_k127_4678241_3	861299.J421_1725	1.428e-20	95.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1725|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4678241_0	196367.JNFG01000008_gene6532	1.834e-192	616.0	COG3829@1|root,COG3852@1|root,COG4191@1|root,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KGEM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS2_k127_4678241_2	1267535.KB906767_gene1910	9.006e-50	181.0	COG4566@1|root,COG4566@2|Bacteria,3Y58V@57723|Acidobacteria,2JJQJ@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4678241_1	196367.JNFG01000008_gene6541	1.754e-84	284.0	COG4566@1|root,COG4566@2|Bacteria,1RAWG@1224|Proteobacteria,2WEM4@28216|Betaproteobacteria,1K7J4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4678241_4	478741.JAFS01000002_gene434	7.436e-11	72.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4678241_5	1267534.KB906755_gene4673	8.608e-10	67.0	COG2273@1|root,COG2273@2|Bacteria,3Y6GF@57723|Acidobacteria,2JKH1@204432|Acidobacteriia	204432|Acidobacteriia	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4686849_3	1267534.KB906755_gene4673	1.203e-05	49.0	COG2273@1|root,COG2273@2|Bacteria,3Y6GF@57723|Acidobacteria,2JKH1@204432|Acidobacteriia	204432|Acidobacteriia	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4686849_2	1227352.C173_05521	1.78e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,1VDV4@1239|Firmicutes,4IPUE@91061|Bacilli,26X10@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4686849_1	317655.Sala_0129	2.085e-09	61.0	COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,2U6HM@28211|Alphaproteobacteria,2K8YU@204457|Sphingomonadales	204457|Sphingomonadales	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4686849_0	2074.JNYD01000003_gene3439	2.807e-196	622.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4E9Y4@85010|Pseudonocardiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GDHHQS2_k127_4703581_5	861299.J421_2691	1.068e-10	68.0	COG1522@1|root,COG1522@2|Bacteria,1ZU0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS2_k127_4703581_1	861299.J421_2689	2.112e-108	370.0	COG0513@1|root,COG0513@2|Bacteria,1ZTQP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DbpA
GDHHQS2_k127_4703581_2	861299.J421_2688	2.868e-95	318.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GDHHQS2_k127_4703581_3	861299.J421_2687	7.709e-73	255.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GDHHQS2_k127_4703581_4	1379270.AUXF01000004_gene3114	3.031e-48	176.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS2_k127_4703581_0	861299.J421_2251	6.172e-167	531.0	COG3525@1|root,COG3525@2|Bacteria,1ZUG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
GDHHQS2_k127_4704801_16	861299.J421_6097	1.716e-08	58.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14,Peptidase_M56
GDHHQS2_k127_4704801_15	861299.J421_4079	6.243e-13	78.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_4079|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS2_k127_4704801_1	1379270.AUXF01000007_gene888	6.098e-158	509.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_4704801_4	42256.RradSPS_3006	1.804e-108	356.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_4704801_8	861299.J421_2257	4.969e-32	131.0	COG1246@1|root,COG1246@2|Bacteria,1ZV2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GDHHQS2_k127_4704801_2	861299.J421_2256	5.281e-119	390.0	COG0500@1|root,COG2226@2|Bacteria,1ZSM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS2_k127_4704801_9	861299.J421_2255	8.348e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,1ZV07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS2_k127_4704801_10	1382304.JNIL01000001_gene50	7.049e-29	125.0	COG4549@1|root,COG4549@2|Bacteria,1V509@1239|Firmicutes,4HH2V@91061|Bacilli,279V7@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unkown function (DUF1775)	ycnI	-	-	-	-	-	-	-	-	-	-	-	DUF1775
GDHHQS2_k127_4704801_12	357808.RoseRS_1500	1.96e-24	118.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi,377H2@32061|Chloroflexia	32061|Chloroflexia	P	copper resistance D domain protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GDHHQS2_k127_4704801_7	379066.GAU_3093	1.005e-43	166.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_4704801_3	861299.J421_2015	8.279e-116	392.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS2_k127_4704801_5	861299.J421_2016	4.112e-108	363.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_4704801_0	861299.J421_2017	0.0	1316.0	COG0841@1|root,COG0841@2|Bacteria,1ZTEK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS2_k127_4704801_6	1234364.AMSF01000027_gene3499	1.396e-70	247.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,1S3D2@1236|Gammaproteobacteria,1X3MK@135614|Xanthomonadales	135614|Xanthomonadales	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
GDHHQS2_k127_4704801_13	1207063.P24_15871	2.997e-23	102.0	COG0614@1|root,COG0614@2|Bacteria,1PK1K@1224|Proteobacteria,2V7TQ@28211|Alphaproteobacteria,2JUUN@204441|Rhodospirillales	204441|Rhodospirillales	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS2_k127_4704878_0	861299.J421_0438	0.0	1045.0	COG3968@1|root,COG3968@2|Bacteria,1ZSPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
GDHHQS2_k127_4722481_3	886293.Sinac_2104	1.785e-52	203.0	COG1680@1|root,COG1680@2|Bacteria,2IWSV@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_4722481_2	861299.J421_4030	2.76e-126	419.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
GDHHQS2_k127_4722481_1	861299.J421_4031	2.907e-305	949.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
GDHHQS2_k127_4722481_4	604354.TSIB_1211	3.189e-50	190.0	arCOG09492@1|root,arCOG09492@2157|Archaea,2Y3AH@28890|Euryarchaeota,244X9@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4722481_0	861299.J421_4032	0.0	1534.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4032|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4722481_5	1379270.AUXF01000001_gene2274	5.825e-33	130.0	28M5H@1|root,2ZAJ9@2|Bacteria,1ZUWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4741673_0	663610.JQKO01000009_gene477	1.851e-174	554.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3NAVA@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
GDHHQS2_k127_4741673_3	1379270.AUXF01000001_gene2572	4.56e-26	119.0	COG0589@1|root,COG0589@2|Bacteria,1ZUMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_4741673_2	861299.J421_0407	1.218e-41	159.0	COG3278@1|root,COG3278@2|Bacteria,1ZU6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
GDHHQS2_k127_4741673_5	1449346.JQMO01000002_gene173	0.0002882	52.0	COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4741673_4	69395.JQLZ01000002_gene1191	2.739e-23	109.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEC@28211|Alphaproteobacteria,2KHNG@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_4741673_1	1123054.KB907735_gene3306	1.356e-62	219.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD binding domain	-	-	1.3.1.72	ko:K09828	ko00100,ko01100,ko01110,map00100,map01100,map01110	M00101	R01457,R03689,R05703,R07488,R07493,R07498,R07499,R07507,R11096	RC00522,RC01887,RC02419	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,Acetyltransf_1,FAD_binding_4,Methyltransf_11
GDHHQS2_k127_4774845_9	861299.J421_1330	1.871e-54	194.0	COG4992@1|root,COG4992@2|Bacteria,1ZTEJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_4774845_10	379066.GAU_0162	2.385e-43	166.0	2CM4I@1|root,340QM@2|Bacteria,1ZTV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4774845_0	861299.J421_1389	3.747e-282	884.0	COG2234@1|root,COG2234@2|Bacteria,1ZSQ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nicastrin	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS2_k127_4774845_7	861299.J421_0519	1.863e-62	224.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	MA20_24885	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K07001,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Acetyltransf_3,cNMP_binding
GDHHQS2_k127_4774845_8	861299.J421_0517	4.076e-59	215.0	COG1647@1|root,COG1647@2|Bacteria,1ZTVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GDHHQS2_k127_4774845_5	861299.J421_0510	8.308e-107	361.0	COG2220@1|root,COG2220@2|Bacteria,1ZUY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS2_k127_4774845_4	861299.J421_0507	1.367e-111	372.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
GDHHQS2_k127_4774845_3	861299.J421_0504	2.298e-145	462.0	COG1398@1|root,COG1398@2|Bacteria,1ZT9N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	-
GDHHQS2_k127_4774845_11	1379270.AUXF01000002_gene1441	2.387e-42	156.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
GDHHQS2_k127_4774845_2	1379270.AUXF01000004_gene2878	6.662e-165	541.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS2_k127_4774845_6	861299.J421_0502	6.143e-73	252.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS2_k127_4774845_1	153721.MYP_1412	1.667e-169	563.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS2_k127_4789284_2	861299.J421_4025	4.085e-105	349.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
GDHHQS2_k127_4789284_0	861299.J421_4024	1.53e-130	434.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_4789284_1	861299.J421_4023	1.674e-109	356.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
GDHHQS2_k127_4789284_3	595460.RRSWK_00672	0.0004509	46.0	COG0367@1|root,COG0367@2|Bacteria,2IYMU@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
GDHHQS2_k127_479148_4	1379270.AUXF01000004_gene3114	1.926e-47	173.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS2_k127_479148_1	861299.J421_2251	6.658e-191	610.0	COG3525@1|root,COG3525@2|Bacteria,1ZUG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
GDHHQS2_k127_479148_0	861299.J421_2685	0.0	1419.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GDHHQS2_k127_479148_3	861299.J421_2684	8.869e-66	233.0	COG0095@1|root,COG0095@2|Bacteria,1ZTY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS2_k127_479148_2	861299.J421_2683	1.623e-76	268.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_4795316_1	1122176.KB903554_gene3791	3.687e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,4NKQV@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4795316_0	861299.J421_0666	2.08e-182	578.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4795316_2	861299.J421_0665	3.769e-18	92.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
GDHHQS2_k127_48512_2	861299.J421_2683	8.681e-95	321.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_48512_1	861299.J421_2682	1.316e-101	340.0	COG0601@1|root,COG0601@2|Bacteria,1ZTP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_48512_3	861299.J421_2681	1.235e-89	304.0	COG1173@1|root,COG1173@2|Bacteria,1ZTMP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_48512_0	861299.J421_2680	1.332e-159	511.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_48637_12	671143.DAMO_2364	8.408e-17	89.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	prhJ	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_48637_8	1408224.SAMCCGM7_c6010	1.51e-40	156.0	2D7A9@1|root,32TNM@2|Bacteria,1RJFR@1224|Proteobacteria,2UAED@28211|Alphaproteobacteria,4BJAM@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_48637_7	1232410.KI421413_gene884	3.141e-46	174.0	COG3794@1|root,COG3794@2|Bacteria,1RGHH@1224|Proteobacteria	1224|Proteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
GDHHQS2_k127_48637_9	1134912.AJTV01000006_gene1241	1.31e-33	133.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2UCUJ@28211|Alphaproteobacteria,36YN3@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS2_k127_48637_5	266117.Rxyl_2566	5.984e-63	221.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	yjbH	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_5
GDHHQS2_k127_48637_6	861299.J421_5670	3.013e-51	192.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_48637_13	931277.C448_03656	5.975e-07	61.0	COG0589@1|root,arCOG02053@2157|Archaea,2XWQF@28890|Euryarchaeota,23VDK@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_48637_0	1382306.JNIM01000001_gene2762	1.971e-159	517.0	COG2079@1|root,COG2079@2|Bacteria,2G8X4@200795|Chloroflexi	200795|Chloroflexi	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GDHHQS2_k127_48637_1	266117.Rxyl_2563	9.093e-132	426.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4CRSB@84995|Rubrobacteria	84995|Rubrobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
GDHHQS2_k127_48637_10	266117.Rxyl_2821	9.526e-26	110.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS2_k127_48637_3	861299.J421_5675	2.14e-101	335.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS2_k127_48637_2	1158292.JPOE01000005_gene1052	1.043e-113	374.0	COG3892@1|root,COG3892@2|Bacteria	2|Bacteria	G	5-dehydro-2-deoxygluconokinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF2090,PfkB
GDHHQS2_k127_48637_4	1266925.JHVX01000001_gene2478	8.638e-100	336.0	COG0122@1|root,COG0122@2|Bacteria,1PDQF@1224|Proteobacteria,2VH56@28216|Betaproteobacteria,373RN@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HhH-GPD superfamily base excision DNA repair protein	alkA	-	3.2.2.21	ko:K01247,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlkA_N,HhH-GPD
GDHHQS2_k127_4866769_0	580332.Slit_2525	1.822e-265	827.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS2_k127_4866769_1	861299.J421_5670	5.214e-38	158.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4887412_4	504728.K649_01455	5.753e-19	96.0	COG2706@1|root,COG2931@1|root,COG5492@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG5492@2|Bacteria,1WNFY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NQ	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS2_k127_4887412_0	360094.PXO_01740	1.239e-44	167.0	COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria,1S826@1236|Gammaproteobacteria,1X74A@135614|Xanthomonadales	135614|Xanthomonadales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS2_k127_4887412_5	330214.NIDE1608	1.572e-15	85.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS2_k127_4887412_6	381764.Fnod_1180	3.036e-06	59.0	COG0296@1|root,COG0296@2|Bacteria,2GD7U@200918|Thermotogae	200918|Thermotogae	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
GDHHQS2_k127_4887412_2	379066.GAU_0474	5.254e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4887412_3	380358.XALC_2530	8.655e-33	131.0	2BH75@1|root,32B8F@2|Bacteria,1QB6K@1224|Proteobacteria,1T6QF@1236|Gammaproteobacteria,1X7EX@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4887412_1	861299.J421_1078	2.372e-38	144.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	ramA	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_4887596_6	861299.J421_6109	6.457e-45	166.0	COG3279@1|root,COG3279@2|Bacteria,1ZUZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS2_k127_4887596_0	234267.Acid_3931	0.0	1264.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_4887596_1	861299.J421_0900	0.0	1013.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS2_k127_4887596_10	1250232.JQNJ01000001_gene2672	3.322e-18	93.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4887596_3	861299.J421_1806	3.737e-64	231.0	COG3258@1|root,COG3258@2|Bacteria,1ZUR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS2_k127_4887596_4	257310.BB4478	7.046e-56	210.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2VQ3S@28216|Betaproteobacteria,3T1BU@506|Alcaligenaceae	28216|Betaproteobacteria	E	Allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B
GDHHQS2_k127_4887596_5	926569.ANT_23220	8.807e-48	180.0	COG2049@1|root,COG2049@2|Bacteria,2G7CU@200795|Chloroflexi	200795|Chloroflexi	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
GDHHQS2_k127_4887596_2	580340.Tlie_0278	7.789e-75	259.0	COG1540@1|root,COG1540@2|Bacteria,3T9Q0@508458|Synergistetes	508458|Synergistetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
GDHHQS2_k127_4887596_7	1038859.AXAU01000015_gene933	4.033e-34	132.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,2UDCH@28211|Alphaproteobacteria,3K0FK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4887596_12	1121373.KB903665_gene3086	4.511e-11	76.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS2_k127_4906883_7	861299.J421_3057	6.74e-95	336.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS2_k127_4906883_18	1379270.AUXF01000005_gene669	3.728e-47	178.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
GDHHQS2_k127_4906883_4	1379270.AUXF01000005_gene668	9.7e-123	411.0	COG0643@1|root,COG0643@2|Bacteria,1ZT7R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	P2 response regulator binding domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
GDHHQS2_k127_4906883_15	1379270.AUXF01000005_gene667	1.348e-56	199.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_4906883_19	592015.HMPREF1705_00008	6.35e-16	85.0	COG0835@1|root,COG0835@2|Bacteria,3TBA6@508458|Synergistetes	508458|Synergistetes	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_4906883_3	861299.J421_3052	1.262e-134	437.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_4906883_17	1379270.AUXF01000005_gene663	3.986e-52	193.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS2_k127_4906883_11	861299.J421_3049	1.089e-67	232.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
GDHHQS2_k127_4906883_0	861299.J421_3048	0.0	1382.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS2_k127_4906883_16	379066.GAU_1397	1.148e-55	199.0	COG3599@1|root,COG3599@2|Bacteria,1ZUSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
GDHHQS2_k127_4906883_8	861299.J421_3047	1.007e-89	300.0	COG0325@1|root,COG3599@1|root,COG0325@2|Bacteria,COG3599@2|Bacteria,1ZTJZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS2_k127_4906883_20	710111.FraQA3DRAFT_2664	8.789e-14	79.0	COG4758@1|root,COG4758@2|Bacteria,2HP3D@201174|Actinobacteria,4EX1Q@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
GDHHQS2_k127_4906883_9	379066.GAU_1769	7.417e-87	302.0	COG0750@1|root,COG0750@2|Bacteria,1ZSKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,Peptidase_M50
GDHHQS2_k127_4906883_1	861299.J421_3406	3.746e-171	546.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS2_k127_4906883_6	861299.J421_3407	7.099e-103	341.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS2_k127_4906883_10	861299.J421_3409	9.427e-71	243.0	COG0233@1|root,COG0233@2|Bacteria,1ZTI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS2_k127_4906883_5	1379270.AUXF01000006_gene121	1.574e-108	355.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_4906883_13	1125863.JAFN01000001_gene969	3.7e-65	229.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS2_k127_4906883_2	861299.J421_3412	2.275e-139	449.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS2_k127_4906883_14	861299.J421_3413	6.19e-57	205.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS2_k127_4906883_12	1379270.AUXF01000006_gene117	3.761e-66	227.0	COG0102@1|root,COG0102@2|Bacteria,1ZTIS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS2_k127_4911860_0	518766.Rmar_1738	2.76e-227	717.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1FJXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GMC oxidoreductase	betA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_4911860_5	1121920.AUAU01000006_gene301	1.921e-49	182.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4911860_1	221288.JH992901_gene2013	6.826e-157	510.0	COG0477@1|root,COG0477@2|Bacteria,1G155@1117|Cyanobacteria,1JK0M@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_4911860_6	1123393.KB891327_gene316	4.089e-16	80.0	2E5C5@1|root,33046@2|Bacteria,1NNAA@1224|Proteobacteria,2W6KD@28216|Betaproteobacteria,1KT4P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS2_k127_4911860_3	1267534.KB906755_gene4573	3.473e-79	274.0	COG0842@1|root,COG0842@2|Bacteria,3Y6GQ@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS2_k127_4911860_2	234267.Acid_6967	4.487e-128	415.0	COG1131@1|root,COG1131@2|Bacteria,3Y78D@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4911860_4	1121423.JONT01000014_gene1270	8.073e-52	199.0	COG0702@1|root,COG0702@2|Bacteria,1UNU6@1239|Firmicutes	1239|Firmicutes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4970271_4	861299.J421_3164	2.461e-169	538.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS2_k127_4970271_21	1379270.AUXF01000005_gene789	1.327e-42	159.0	COG0234@1|root,COG0234@2|Bacteria,1ZTZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS2_k127_4970271_19	767817.Desgi_0313	5.118e-57	211.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS2_k127_4970271_18	379066.GAU_1534	2.576e-61	220.0	COG0340@1|root,COG0340@2|Bacteria,1ZTQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
GDHHQS2_k127_4970271_13	379066.GAU_1533	4.676e-94	322.0	COG1968@1|root,COG1968@2|Bacteria,1ZU3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS2_k127_4970271_5	861299.J421_3157	3.135e-167	535.0	COG0438@1|root,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4970271_11	1379270.AUXF01000005_gene785	1.164e-99	333.0	COG0324@1|root,COG0324@2|Bacteria,1ZTBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS2_k127_4970271_0	861299.J421_3155	1.193e-229	726.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS2_k127_4970271_7	861299.J421_3153	1.339e-142	476.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS2_k127_4970271_9	861299.J421_1138	4.627e-125	409.0	COG2304@1|root,COG2304@2|Bacteria,1ZSVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1194)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS2_k127_4970271_20	379066.GAU_1526	2.376e-47	183.0	29X7F@1|root,30IWP@2|Bacteria,1ZTUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4970271_8	861299.J421_3151	1.211e-131	427.0	COG1721@1|root,COG1721@2|Bacteria,1ZSKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_4970271_6	861299.J421_3150	1.226e-161	514.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_4970271_14	861299.J421_3149	8.965e-93	320.0	COG1187@1|root,COG1187@2|Bacteria,1ZT5B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_4970271_24	1536774.H70357_23930	5.83e-30	126.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,26SV4@186822|Paenibacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS2_k127_4970271_12	1379270.AUXF01000005_gene775	1.4e-95	325.0	COG1354@1|root,COG1354@2|Bacteria,1ZT1G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS2_k127_4970271_15	379066.GAU_1520	1.57e-92	310.0	COG1994@1|root,COG1994@2|Bacteria,1ZTIB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_4970271_26	861299.J421_3145	1.288e-20	94.0	COG0268@1|root,COG0268@2|Bacteria,1ZU6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS2_k127_4970271_25	861299.J421_3144	4.796e-22	106.0	COG1196@1|root,COG1196@2|Bacteria,1ZU4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4970271_1	861299.J421_3143	2.041e-208	672.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_4970271_3	861299.J421_3142	5.414e-172	544.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS2_k127_4970271_16	379066.GAU_1514	1.352e-78	266.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GDHHQS2_k127_4970271_17	1300345.LF41_1458	3.257e-69	250.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,Peptidase_M29
GDHHQS2_k127_4970271_22	1379270.AUXF01000002_gene1484	1.087e-38	153.0	2B3Y0@1|root,31WN1@2|Bacteria,1ZUEY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4970271_10	861299.J421_4341	1.633e-103	344.0	COG2084@1|root,COG2084@2|Bacteria,1ZT54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS2_k127_4970271_2	378806.STAUR_1231	4.158e-194	615.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YZ0Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_4970271_23	861299.J421_4441	1.042e-36	147.0	COG1434@1|root,COG1434@2|Bacteria,1ZV4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_4972196_0	861299.J421_4196	0.0	1111.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS2_k127_4972196_3	1379270.AUXF01000001_gene2793	1.038e-70	249.0	COG1131@1|root,COG1131@2|Bacteria,1ZTRV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS2_k127_4972196_2	861299.J421_4191	4.447e-92	308.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS2_k127_4972196_6	644968.DFW101_1115	2.815e-05	49.0	2ARU2@1|root,31H5K@2|Bacteria,1QEUQ@1224|Proteobacteria,4362C@68525|delta/epsilon subdivisions,2X9EZ@28221|Deltaproteobacteria,2MCP3@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4972196_4	861299.J421_4190	1.048e-69	246.0	COG0755@1|root,COG0755@2|Bacteria,1ZTJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS2_k127_4972196_1	1303518.CCALI_01058	2.932e-149	482.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS2_k127_4972196_5	266117.Rxyl_1977	2.505e-53	198.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS2_k127_5001940_4	639030.JHVA01000001_gene3713	2.345e-62	223.0	COG2823@1|root,COG2823@2|Bacteria,3Y7T6@57723|Acidobacteria,2JN0K@204432|Acidobacteriia	204432|Acidobacteriia	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_5001940_3	483219.LILAB_29390	6.841e-67	236.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2X0CC@28221|Deltaproteobacteria,2Z0IE@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS2_k127_5001940_0	1173024.KI912151_gene2146	5.252e-188	596.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
GDHHQS2_k127_5001940_2	693986.MOC_4620	3.221e-75	259.0	COG0412@1|root,COG0412@2|Bacteria,1R6AF@1224|Proteobacteria,2U0YG@28211|Alphaproteobacteria,1JUW3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_5001940_11	1094980.Mpsy_1166	1.089e-21	101.0	COG0517@1|root,arCOG00606@2157|Archaea,2XZ85@28890|Euryarchaeota,2N9UA@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_5001940_1	1392490.JHZX01000001_gene2235	2.844e-104	344.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_5001940_13	749222.Nitsa_1475	6.743e-15	80.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS2_k127_5001940_7	525904.Tter_2724	3.511e-38	147.0	COG3439@1|root,COG3439@2|Bacteria,2NPV1@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GDHHQS2_k127_5001940_9	78245.Xaut_1403	4.291e-34	138.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2U9JR@28211|Alphaproteobacteria,3EZV0@335928|Xanthobacteraceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5001940_17	477974.Daud_1641	0.0002106	53.0	COG0589@1|root,COG0589@2|Bacteria,1VF2J@1239|Firmicutes,24SWJ@186801|Clostridia	186801|Clostridia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_5001940_6	861299.J421_5747	4.004e-60	217.0	2AEQK@1|root,314M5@2|Bacteria,1ZTRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
GDHHQS2_k127_5001940_14	1210908.HSB1_47760	4.458e-09	61.0	COG0701@1|root,arCOG02712@2157|Archaea,2XU5I@28890|Euryarchaeota,23T00@183963|Halobacteria	183963|Halobacteria	S	metal ion permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,YHS
GDHHQS2_k127_5001940_5	1117943.SFHH103_02774	8.053e-62	230.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_5001940_10	1382356.JQMP01000003_gene1440	4.253e-30	132.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_5001940_16	379066.GAU_2766	7.494e-05	46.0	COG2132@1|root,COG2132@2|Bacteria,1ZUZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
GDHHQS2_k127_5001940_12	330214.NIDE1139	2.404e-21	98.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,DUF3565
GDHHQS2_k127_5001940_8	1210884.HG799465_gene11637	4.944e-38	149.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
GDHHQS2_k127_5028315_0	1304874.JAFY01000002_gene144	9.678e-61	218.0	COG0745@1|root,COG0745@2|Bacteria,3TATD@508458|Synergistetes	508458|Synergistetes	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_5028315_4	1342301.JASD01000008_gene3188	5.342e-07	57.0	2C5FY@1|root,33BY6@2|Bacteria,1NH37@1224|Proteobacteria,2UJVQ@28211|Alphaproteobacteria,3ZY7Q@60136|Sulfitobacter	28211|Alphaproteobacteria	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
GDHHQS2_k127_5028315_3	1132855.KB913035_gene232	2.301e-10	62.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,2KKH2@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS2_k127_5028315_1	1122604.JONR01000017_gene4315	1.389e-47	175.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1X6GE@135614|Xanthomonadales	135614|Xanthomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
GDHHQS2_k127_5028315_2	1286631.X805_01660	7.64e-20	93.0	COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,2VXNU@28216|Betaproteobacteria,1KN77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS2_k127_5029402_1	1379270.AUXF01000001_gene2274	6.488e-80	279.0	28M5H@1|root,2ZAJ9@2|Bacteria,1ZUWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5029402_0	1379270.AUXF01000001_gene2272	2.643e-87	294.0	COG1524@1|root,COG1524@2|Bacteria,1ZUMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_5063930_1	861299.J421_2683	2.885e-156	510.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_5063930_5	330214.NIDE4014	4.794e-42	171.0	2EUIU@1|root,33N0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5063930_3	861299.J421_0834	8.629e-88	301.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	MA20_24580	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS2_k127_5063930_2	1242864.D187_002504	5.729e-117	383.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_5063930_6	861299.J421_1299	5.499e-28	121.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
GDHHQS2_k127_5063930_0	1379270.AUXF01000001_gene2826	1.89e-185	586.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS2_k127_5063930_4	861299.J421_4157	3.469e-51	184.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS2_k127_5071693_1	861299.J421_3779	6.067e-30	122.0	COG2261@1|root,COG2261@2|Bacteria,1ZU62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_5071693_2	1396418.BATQ01000056_gene243	1.022e-21	97.0	COG2261@1|root,COG2261@2|Bacteria,46YR6@74201|Verrucomicrobia,2IW8G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_5071693_0	861299.J421_3780	1.382e-210	661.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS2_k127_5087876_0	1379270.AUXF01000006_gene304	1.216e-166	527.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS2_k127_5087876_1	1123508.JH636445_gene6811	7.031e-80	286.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
GDHHQS2_k127_5087876_3	1379270.AUXF01000006_gene306	9.464e-52	187.0	COG3880@1|root,COG3880@2|Bacteria,1ZTPQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
GDHHQS2_k127_5087876_2	861299.J421_3214	1.162e-59	209.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GDHHQS2_k127_5100716_4	861299.J421_3018	2.099e-07	53.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	2|Bacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GDHHQS2_k127_5100716_3	379066.GAU_2486	1.031e-49	181.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_5100716_0	861299.J421_3942	5.978e-151	485.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_5100716_2	861299.J421_3940	1.453e-59	218.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_5100716_1	861299.J421_3940	6.494e-74	254.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_5132064_3	861299.J421_1574	1.149e-111	375.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS2_k127_5132064_7	861299.J421_2126	4.447e-07	59.0	2C5K1@1|root,2ZR6Y@2|Bacteria,1ZV9C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5132064_5	861299.J421_3723	1.538e-22	109.0	COG0457@1|root,COG2206@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE6_C,DICT,GerE,HD,HD_5
GDHHQS2_k127_5132064_8	379066.GAU_1034	2.933e-06	58.0	2C5K1@1|root,2ZR6Y@2|Bacteria,1ZV9C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5132064_6	1463864.JOGO01000026_gene2756	7.294e-11	74.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
GDHHQS2_k127_5132064_4	880073.Calab_1265	3.709e-82	286.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_5132064_2	861299.J421_1574	6.602e-127	425.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS2_k127_5132064_1	861299.J421_2683	3.53e-160	524.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_5132064_0	1379270.AUXF01000003_gene3556	5.714e-270	836.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS2_k127_522888_5	1379270.AUXF01000003_gene3853	3.274e-133	430.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS2_k127_522888_8	861299.J421_3606	1.878e-56	198.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
GDHHQS2_k127_522888_1	251221.35214024	7.347e-208	663.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS2_k127_522888_4	379066.GAU_1999	4.935e-147	479.0	COG3876@1|root,COG3876@2|Bacteria,1ZUBN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
GDHHQS2_k127_522888_7	861299.J421_5981	6.357e-69	250.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5981|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_522888_6	861299.J421_3602	1.222e-70	245.0	COG0558@1|root,COG0558@2|Bacteria,1ZTIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_522888_0	861299.J421_3601	1.217e-256	794.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GDHHQS2_k127_522888_11	379066.GAU_1996	2.093e-29	132.0	296W8@1|root,2ZU51@2|Bacteria,1ZU4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_522888_10	1379270.AUXF01000003_gene3861	1.346e-31	131.0	2FD8C@1|root,345AC@2|Bacteria,1ZTXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_522888_3	861299.J421_3598	7.921e-174	554.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_522888_2	861299.J421_3597	3.189e-178	564.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_522888_13	379066.GAU_1994	2.457e-19	97.0	293YK@1|root,2ZRDM@2|Bacteria,1ZU6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_522888_9	861299.J421_3595	1.215e-33	135.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_526884_6	861299.J421_3564	3.775e-64	220.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS2_k127_526884_1	861299.J421_3563	0.0	1087.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS2_k127_526884_0	861299.J421_3561	0.0	1097.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS2_k127_526884_7	861299.J421_3560	2.087e-57	203.0	COG0802@1|root,COG0802@2|Bacteria,1ZTY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
GDHHQS2_k127_526884_8	861299.J421_3559	1.04e-35	145.0	COG1214@1|root,COG1214@2|Bacteria,1ZU16@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GDHHQS2_k127_526884_9	861299.J421_3558	1.193e-31	134.0	COG0454@1|root,COG0456@2|Bacteria,1ZU09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS2_k127_526884_5	861299.J421_3557	1.888e-66	231.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS2_k127_526884_13	1122603.ATVI01000006_gene615	1.174e-13	83.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1X3I7@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS2_k127_526884_12	1125863.JAFN01000001_gene1124	9.013e-22	105.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS2_k127_526884_11	326427.Cagg_1264	1.035e-26	120.0	COG1010@1|root,COG1648@1|root,COG2073@1|root,COG1010@2|Bacteria,COG1648@2|Bacteria,COG2073@2|Bacteria,2G7UU@200795|Chloroflexi,376JW@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	1.3.1.76,2.1.1.131,3.7.1.12,4.99.1.4	ko:K02304,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05180,R05809,R07772	RC00003,RC01012,RC01034,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid,NAD_binding_7,TP_methylase
GDHHQS2_k127_526884_3	644966.Tmar_1263	4.868e-90	312.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS2_k127_526884_2	379066.GAU_1946	1.23e-127	417.0	COG1087@1|root,COG1087@2|Bacteria,1ZSX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_526884_4	861299.J421_3554	1.726e-82	282.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS2_k127_526884_10	1379270.AUXF01000006_gene15	1.543e-30	122.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_5343501_3	861299.J421_4386	1.191e-129	421.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_5343501_4	661478.OP10G_3097	3.663e-116	390.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
GDHHQS2_k127_5343501_1	861299.J421_1994	3.012e-188	605.0	COG2989@1|root,COG2989@2|Bacteria,1ZUAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative peptidoglycan binding domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GDHHQS2_k127_5343501_0	861299.J421_1043	1.263e-229	722.0	COG0467@1|root,COG0467@2|Bacteria,1ZUWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS2_k127_5343501_2	861299.J421_1044	6.592e-175	568.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1044|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5343501_5	644966.Tmar_2012	1.579e-104	348.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_5402559_0	1379270.AUXF01000002_gene1567	1.731e-112	382.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5402559_1	1379270.AUXF01000007_gene1044	1.564e-36	153.0	COG0077@1|root,COG0077@2|Bacteria,1ZTXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
GDHHQS2_k127_5402559_2	1121423.JONT01000008_gene823	2.654e-28	128.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,262D3@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GDHHQS2_k127_5480391_2	1379270.AUXF01000005_gene487	4.898e-79	278.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS2_k127_5480391_0	357808.RoseRS_1753	1.255e-166	533.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,374V4@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_5480391_1	861299.J421_2927	4.545e-87	293.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS2_k127_5482257_5	378806.STAUR_7458	3.571e-45	166.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,43AM1@68525|delta/epsilon subdivisions,2X616@28221|Deltaproteobacteria,2Z388@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_5482257_2	290397.Adeh_3813	2.511e-76	259.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_5482257_6	861299.J421_3646	8.745e-32	134.0	2ENGP@1|root,33G46@2|Bacteria,1ZU71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS2_k127_5482257_0	861299.J421_0062	7.964e-173	552.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_5482257_1	1329516.JPST01000003_gene1162	1.492e-87	300.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS2_k127_5493794_1	880073.Calab_0881	5.423e-101	363.0	COG0210@1|root,COG0210@2|Bacteria,2NQHW@2323|unclassified Bacteria	2|Bacteria	L	3' exoribonuclease, RNase T-like	-	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RNase_T,UvrD-helicase,UvrD_C
GDHHQS2_k127_5493794_4	1267535.KB906767_gene3090	2.677e-35	138.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
GDHHQS2_k127_5493794_5	1267534.KB906760_gene1554	1.975e-07	59.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5493794_2	861299.J421_1951	1.297e-50	189.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS2_k127_5493794_0	861299.J421_4060	0.0	1161.0	COG2352@1|root,COG2352@2|Bacteria,1ZSSH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
GDHHQS2_k127_5493794_3	861299.J421_2231	1e-35	139.0	COG3568@1|root,COG3568@2|Bacteria,1ZV66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS2_k127_5520249_5	861299.J421_3442	8.548e-24	107.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GDHHQS2_k127_5520249_0	1379270.AUXF01000006_gene86	5.024e-232	743.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS2_k127_5520249_1	861299.J421_3445	9.395e-134	434.0	COG0016@1|root,COG0016@2|Bacteria,1ZSQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS2_k127_5520249_3	861299.J421_3446	1.156e-51	184.0	COG0292@1|root,COG0292@2|Bacteria,1ZTUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS2_k127_5520249_7	1379270.AUXF01000006_gene83	1.457e-19	90.0	COG0291@1|root,COG0291@2|Bacteria,1ZU3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS2_k127_5520249_2	379066.GAU_1878	2.332e-79	268.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS2_k127_5520249_6	1267534.KB906754_gene3149	5.095e-23	103.0	COG0346@1|root,COG0346@2|Bacteria,3Y5G5@57723|Acidobacteria,2JJZG@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_5520249_4	861299.J421_3449	4.91e-43	158.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_5536969_0	861299.J421_1204	1.524e-213	672.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS2_k127_5536969_1	861299.J421_1205	1.455e-169	557.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD3	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
GDHHQS2_k127_5536969_3	1146883.BLASA_1918	2.855e-38	150.0	COG2905@1|root,COG2905@2|Bacteria,2I5MP@201174|Actinobacteria,4EXD4@85013|Frankiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_5536969_2	1210884.HG799464_gene10502	4.612e-72	265.0	COG0515@1|root,COG2203@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_5550379_1	1379270.AUXF01000001_gene2417	8.514e-66	235.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS2_k127_5550379_2	489825.LYNGBM3L_21480	2.356e-20	96.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HGCH@1150|Oscillatoriales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_5550379_0	1095769.CAHF01000005_gene1469	2.745e-76	259.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
GDHHQS2_k127_5559288_1	861299.J421_2334	5.463e-75	258.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS2_k127_5559288_0	379066.GAU_0440	4.87e-105	347.0	COG1960@1|root,COG1960@2|Bacteria,1ZUHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_5559981_1	861299.J421_2445	1.335e-111	371.0	COG0596@1|root,COG0596@2|Bacteria,1ZTAV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
GDHHQS2_k127_5559981_0	1379270.AUXF01000004_gene3355	5.104e-160	514.0	COG1363@1|root,COG1363@2|Bacteria,1ZTF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS2_k127_5559981_3	1519464.HY22_05730	5.196e-70	260.0	COG3975@1|root,COG3975@2|Bacteria,1FEP2@1090|Chlorobi	1090|Chlorobi	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
GDHHQS2_k127_5559981_2	379066.GAU_0555	4.664e-75	253.0	COG1960@1|root,COG1960@2|Bacteria,1ZT6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_5561828_4	861299.J421_3073	4.505e-139	447.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
GDHHQS2_k127_5561828_2	861299.J421_3074	2.76e-159	515.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_5561828_3	861299.J421_3075	6.361e-143	463.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_5561828_5	861299.J421_3076	6.748e-131	427.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS2_k127_5561828_1	861299.J421_3077	6.795e-171	548.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_5561828_6	861299.J421_3078	4.893e-59	214.0	COG1589@1|root,COG1589@2|Bacteria,1ZTRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
GDHHQS2_k127_5561828_0	1379270.AUXF01000005_gene693	5.662e-179	571.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS2_k127_5591100_9	521098.Aaci_2608	0.0003189	45.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes	1239|Firmicutes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
GDHHQS2_k127_5591100_7	861299.J421_2941	1.457e-47	179.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GDHHQS2_k127_5591100_2	379066.GAU_1191	4.444e-159	507.0	COG2876@1|root,COG2876@2|Bacteria,1ZTB0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS2_k127_5591100_0	861299.J421_2945	0.0	1245.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS2_k127_5591100_5	861299.J421_2946	1.67e-68	251.0	COG3087@1|root,COG3087@2|Bacteria,1ZTII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GDHHQS2_k127_5591100_3	861299.J421_2947	2.755e-116	391.0	COG3087@1|root,COG3087@2|Bacteria,1ZSYS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GDHHQS2_k127_5591100_1	861299.J421_2948	0.0	1135.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
GDHHQS2_k127_5591100_8	861299.J421_2949	2.628e-46	171.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS2_k127_5591100_6	379066.GAU_1203	3.884e-65	226.0	COG0359@1|root,COG0359@2|Bacteria,1ZTNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS2_k127_5591100_4	861299.J421_2951	1.62e-69	247.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
GDHHQS2_k127_5602002_0	861299.J421_2504	2.238e-220	692.0	COG0372@1|root,COG0372@2|Bacteria,1ZT4W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_5602002_1	1146883.BLASA_1778	1.153e-171	549.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EVYU@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GDHHQS2_k127_5602342_2	861299.J421_4200	1.526e-62	220.0	COG0596@1|root,COG0596@2|Bacteria,1ZTSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_5602342_4	861299.J421_4201	5.607e-25	106.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5602342_3	861299.J421_4203	2.921e-37	157.0	COG0558@1|root,COG0558@2|Bacteria,1ZTUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_5602342_1	861299.J421_4205	1.349e-125	419.0	2EY14@1|root,33RA2@2|Bacteria,1ZSR5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5602342_0	861299.J421_4207	2.704e-189	607.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5603503_4	632245.CLP_0353	1.847e-47	179.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,36IUU@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
GDHHQS2_k127_5603503_5	1385510.N781_00780	3.415e-23	101.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,4HKWM@91061|Bacilli	91061|Bacilli	K	Transcriptional	sdpR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS2_k127_5603503_1	234267.Acid_2458	5.567e-124	406.0	COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria	57723|Acidobacteria	H	PFAM delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
GDHHQS2_k127_5603503_2	379066.GAU_2594	6.337e-99	332.0	COG0181@1|root,COG0181@2|Bacteria,1ZTQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS2_k127_5603503_0	266117.Rxyl_1977	1.493e-141	471.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS2_k127_5603503_3	1142394.PSMK_27530	1.28e-84	285.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS2_k127_5611263_2	1089550.ATTH01000001_gene2186	3.111e-57	205.0	COG5340@1|root,COG5340@2|Bacteria,4NSQC@976|Bacteroidetes	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
GDHHQS2_k127_5611263_3	1267535.KB906767_gene3584	5.673e-30	131.0	29WUK@1|root,30IG1@2|Bacteria,3Y5ZU@57723|Acidobacteria,2JNSB@204432|Acidobacteriia	204432|Acidobacteriia	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
GDHHQS2_k127_5611263_4	1035308.AQYY01000002_gene145	4.325e-26	120.0	2DEQR@1|root,2ZNVU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5611263_1	351348.Maqu_3188	2.258e-78	274.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	istB3	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
GDHHQS2_k127_5611263_0	768671.ThimaDRAFT_4865	2.281e-164	533.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS2_k127_5614261_0	861299.J421_2672	1.122e-144	466.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5614261_2	379066.GAU_1207	2.657e-82	283.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
GDHHQS2_k127_5614261_1	861299.J421_2674	2.707e-84	286.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
GDHHQS2_k127_5614261_3	1125863.JAFN01000001_gene535	9.85e-57	212.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5614261_4	1303518.CCALI_01736	9.811e-55	201.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS2_k127_5614261_5	861299.J421_2677	1.91e-48	182.0	COG4775@1|root,COG4775@2|Bacteria,1ZTG1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5616127_2	760117.JN27_07085	3.884e-37	143.0	COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2VTBE@28216|Betaproteobacteria,475Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_5616127_1	861299.J421_1752	4.497e-43	171.0	2DWGD@1|root,3407S@2|Bacteria,1ZV24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5616127_3	700598.Niako_2458	4.649e-17	83.0	2E328@1|root,32Y2G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5616127_0	1379270.AUXF01000002_gene1577	5.868e-137	459.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5616343_11	84531.JMTZ01000068_gene1720	2.338e-05	57.0	COG1409@1|root,COG1409@2|Bacteria,1N44U@1224|Proteobacteria,1RY17@1236|Gammaproteobacteria,1X3WN@135614|Xanthomonadales	135614|Xanthomonadales	S	calcineurin phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
GDHHQS2_k127_5616343_1	861299.J421_4541	9.184e-47	177.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_5616343_5	330214.NIDE1608	1.38e-18	94.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS2_k127_5616343_2	861299.J421_4538	8.075e-38	157.0	2C9AW@1|root,2ZVNX@2|Bacteria,1ZUAK@142182|Gemmatimonadetes	861299.J421_4538|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5616343_9	861299.J421_1305	7.72e-10	69.0	28YSJ@1|root,343H2@2|Bacteria,1ZU2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5616343_6	861299.J421_1152	4.43e-16	87.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_5616343_0	1192124.LIG30_4270	1.305e-50	192.0	COG0332@1|root,COG0332@2|Bacteria,1RARU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM 3-oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS2_k127_5616343_4	877455.Metbo_0278	7.969e-29	132.0	COG0451@1|root,COG1022@1|root,arCOG01369@2157|Archaea,arCOG04199@2157|Archaea,2XT0U@28890|Euryarchaeota	28890|Euryarchaeota	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS2_k127_5616343_8	1121946.AUAX01000002_gene93	3.405e-14	80.0	COG0172@1|root,COG0172@2|Bacteria,2GKVE@201174|Actinobacteria,4DFWQ@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2b
GDHHQS2_k127_5636244_5	861299.J421_6331	1.351e-45	166.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS2_k127_5636244_0	1095769.CAHF01000005_gene1477	3.549e-112	375.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,475FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
GDHHQS2_k127_5636244_3	1242864.D187_003015	4.856e-99	349.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4
GDHHQS2_k127_5636244_4	234267.Acid_1844	1.008e-52	192.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_5636244_7	1479239.JQMU01000001_gene1659	1.4e-26	117.0	COG5528@1|root,COG5528@2|Bacteria,1MYF3@1224|Proteobacteria,2VGW5@28211|Alphaproteobacteria,2K5ER@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GDHHQS2_k127_5636244_2	379066.GAU_2793	1.436e-103	344.0	COG2321@1|root,COG2321@2|Bacteria,1ZSN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS2_k127_5636244_1	926560.KE387023_gene2723	1.704e-104	349.0	COG3437@1|root,COG3437@2|Bacteria,1WM50@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
GDHHQS2_k127_5636244_6	1210884.HG799466_gene12816	1.067e-29	132.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_5691606_2	861299.J421_2433	3.172e-55	195.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_5691606_0	861299.J421_1125	8.428e-156	500.0	COG0208@1|root,COG0208@2|Bacteria,1ZTAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
GDHHQS2_k127_5691606_4	323848.Nmul_A1488	2.271e-13	77.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,2VY5U@28216|Betaproteobacteria,373KS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
GDHHQS2_k127_5691606_1	861299.J421_1044	1.458e-60	222.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1044|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5691606_3	861299.J421_3035	5.701e-48	175.0	COG0526@1|root,COG0526@2|Bacteria,1ZU4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
GDHHQS2_k127_5694724_0	861299.J421_2352	9.997e-198	625.0	COG4102@1|root,COG4102@2|Bacteria,1ZSZ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_5694724_1	861299.J421_2353	1.982e-189	609.0	COG5267@1|root,COG5267@2|Bacteria,1ZSPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_5694724_3	379066.GAU_0674	1.933e-109	372.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUFI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_5694724_5	1254432.SCE1572_17210	2.285e-40	156.0	COG0454@1|root,COG0454@2|Bacteria,1QZHM@1224|Proteobacteria,43CIQ@68525|delta/epsilon subdivisions,2WWHV@28221|Deltaproteobacteria,2Z207@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_5694724_6	1403819.BATR01000184_gene6379	3.729e-13	76.0	2EH3D@1|root,33AVD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GDHHQS2_k127_5694724_7	1453505.JASY01000003_gene2003	1.642e-12	75.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,1I2VX@117743|Flavobacteriia,2NWSB@237|Flavobacterium	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
GDHHQS2_k127_5694724_4	631454.N177_2972	2.628e-63	228.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,2U5TK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS2_k127_5694724_2	861299.J421_1695	1.207e-183	589.0	COG0457@1|root,COG0457@2|Bacteria,1ZV58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5694724_8	591157.SSLG_00792	2.415e-09	60.0	COG0637@1|root,COG0637@2|Bacteria,2GNX0@201174|Actinobacteria	201174|Actinobacteria	V	TIGRFAM HAD-superfamily hydrolase subfamily IA, variant 3	yfbT	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
GDHHQS2_k127_5718195_4	1294273.roselon_01710	6.467e-69	252.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS2_k127_5718195_7	592029.DDD_0935	2.346e-51	192.0	COG5266@1|root,COG5266@2|Bacteria,4NI88@976|Bacteroidetes,1I0C0@117743|Flavobacteriia,3HKZW@363408|Nonlabens	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
GDHHQS2_k127_5718195_8	637905.SVI_2131	1.439e-16	89.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QAS3@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidase inhibitor I9	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PPC,Peptidase_S8
GDHHQS2_k127_5718195_6	1379270.AUXF01000004_gene3157	8.102e-63	231.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5718195_0	1379270.AUXF01000004_gene3156	0.0	1085.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1ZTBA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_5718195_3	1379270.AUXF01000004_gene3155	3.181e-124	419.0	28PJE@1|root,2ZC90@2|Bacteria,1ZTV5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
GDHHQS2_k127_5718195_2	1379270.AUXF01000004_gene3158	1.147e-144	480.0	COG2755@1|root,COG2755@2|Bacteria,1ZUW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_5718195_9	998674.ATTE01000001_gene3668	2.61e-14	74.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,1SHN2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5718195_12	82654.Pse7367_2151	9.515e-05	50.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria,1HB8R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5718195_1	861299.J421_6044	4.089e-247	776.0	COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS2_k127_5718195_5	1379270.AUXF01000004_gene3043	4.85e-66	228.0	COG0048@1|root,COG0048@2|Bacteria,1ZTN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS2_k127_5718195_10	861299.J421_2770	9.551e-13	72.0	COG0049@1|root,COG0049@2|Bacteria,1ZSQZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS2_k127_5719001_7	1379270.AUXF01000004_gene3358	6.623e-34	135.0	2C4KS@1|root,30283@2|Bacteria,1ZUZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5719001_1	861299.J421_2444	6.178e-218	690.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1ZTG4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5
GDHHQS2_k127_5719001_3	379066.GAU_0535	1.932e-77	287.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GDHHQS2_k127_5719001_5	1379270.AUXF01000002_gene1856	6.35e-66	228.0	COG0652@1|root,COG0652@2|Bacteria,1ZTQ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS2_k127_5719001_6	861299.J421_2438	1.104e-52	194.0	COG1309@1|root,COG1309@2|Bacteria,1ZTT6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GDHHQS2_k127_5719001_4	861299.J421_2432	7.532e-71	243.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5719001_13	861299.J421_2430	3.199e-08	62.0	298DU@1|root,2ZVJ1@2|Bacteria,1ZU76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5719001_14	1112217.PPL19_15474	1.225e-05	51.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_5719001_0	861299.J421_2428	1.074e-245	773.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GDHHQS2_k127_5719001_8	1379270.AUXF01000003_gene3372	3.556e-33	133.0	COG1188@1|root,COG1188@2|Bacteria,1ZTXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
GDHHQS2_k127_5719001_11	861299.J421_2918	1.143e-13	79.0	2FCTB@1|root,344W9@2|Bacteria,1ZU4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5719001_9	379066.GAU_0520	4.056e-26	119.0	COG0265@1|root,COG0265@2|Bacteria,1ZTV0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
GDHHQS2_k127_5719001_2	945713.IALB_0512	8.707e-113	375.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GDHHQS2_k127_5719001_10	543526.Htur_0026	5.902e-20	101.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,23TMB@183963|Halobacteria	183963|Halobacteria	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS2_k127_5719368_11	861299.J421_2941	4.486e-22	99.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GDHHQS2_k127_5719368_10	1123399.AQVE01000007_gene1152	5.116e-27	123.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,1S847@1236|Gammaproteobacteria,463HS@72273|Thiotrichales	72273|Thiotrichales	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GDHHQS2_k127_5719368_0	861299.J421_2940	6.113e-175	565.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
GDHHQS2_k127_5719368_6	861299.J421_2939	1.247e-57	211.0	COG0125@1|root,COG0125@2|Bacteria,1ZTPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS2_k127_5719368_7	861299.J421_2938	1.38e-42	158.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
GDHHQS2_k127_5719368_4	861299.J421_2937	1.734e-82	284.0	COG2890@1|root,COG2890@2|Bacteria,1ZTQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
GDHHQS2_k127_5719368_1	379066.GAU_1184	4.216e-145	467.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_5719368_8	269799.Gmet_0377	4.223e-27	112.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS2_k127_5719368_5	296591.Bpro_0708	1.543e-63	238.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1PF0H@1224|Proteobacteria,2W8ZC@28216|Betaproteobacteria,4AI7H@80864|Comamonadaceae	28216|Betaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,MASE1
GDHHQS2_k127_5719368_9	1469245.JFBG01000083_gene257	4.451e-27	119.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GDHHQS2_k127_5719368_3	861299.J421_2931	4.201e-116	388.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
GDHHQS2_k127_5719368_2	861299.J421_2930	2.947e-141	456.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_5738033_0	1173025.GEI7407_2021	5.635e-19	93.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5278@2|Bacteria,1G13T@1117|Cyanobacteria,1HI4W@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_5786107_1	29581.BW37_03287	1.075e-93	317.0	COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2VTBE@28216|Betaproteobacteria,475Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS2_k127_5786107_0	861299.J421_3960	8.203e-148	475.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS2_k127_5786107_3	1313421.JHBV01000007_gene4227	2.395e-23	115.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
GDHHQS2_k127_5786107_5	1120965.AUBV01000015_gene1141	1.221e-15	91.0	COG3291@1|root,COG4935@1|root,COG5184@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB
GDHHQS2_k127_5786107_4	1485545.JQLW01000010_gene1493	1.051e-21	110.0	COG1572@1|root,COG3386@1|root,COG1572@2|Bacteria,COG3386@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
GDHHQS2_k127_5786107_2	861299.J421_3958	3.944e-59	209.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
GDHHQS2_k127_5786107_6	1379270.AUXF01000003_gene3419	1.156e-12	71.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_5789273_4	383372.Rcas_0743	3.931e-34	147.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8QT@200795|Chloroflexi,376YD@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS2_k127_5789273_6	378806.STAUR_8052	1.778e-05	53.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5789273_0	861299.J421_3743	1.842e-148	492.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS2_k127_5789273_1	269799.Gmet_1918	3.027e-132	445.0	COG2197@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2197@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_5789273_3	497964.CfE428DRAFT_0676	5.856e-61	217.0	COG0745@1|root,COG0745@2|Bacteria,46Z7M@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_5789273_2	269799.Gmet_0011	4.708e-113	392.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,43C40@68525|delta/epsilon subdivisions,2X7EG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	fgrK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_5789273_5	883.DvMF_0064	1.612e-06	51.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Hpt,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_5792248_2	379066.GAU_3703	1.268e-47	173.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_5792248_0	1147.D082_21510	9.105e-116	385.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	yteR	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
GDHHQS2_k127_5792248_1	1207076.ALAT01000184_gene2792	1.294e-73	255.0	2DMRI@1|root,32T77@2|Bacteria,1N4QH@1224|Proteobacteria,1S9U1@1236|Gammaproteobacteria,1Z0R9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GDHHQS2_k127_5792248_4	398767.Glov_3470	2.402e-28	130.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_5792248_3	861299.J421_2129	3.623e-46	179.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_5792248_5	378806.STAUR_0350	7.512e-08	55.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,4382M@68525|delta/epsilon subdivisions,2X3CP@28221|Deltaproteobacteria,2YVFV@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_5843678_5	861299.J421_0897	1.702e-94	311.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS2_k127_5843678_10	1379270.AUXF01000002_gene1159	7.202e-28	122.0	COG0810@1|root,COG0810@2|Bacteria,1ZV4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_5843678_0	861299.J421_0903	0.0	1112.0	COG0249@1|root,COG0249@2|Bacteria,1ZST5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS2_k127_5843678_7	1379270.AUXF01000002_gene1165	3.964e-39	160.0	COG1729@1|root,COG3087@1|root,COG1729@2|Bacteria,COG3087@2|Bacteria,1ZTSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_6
GDHHQS2_k127_5843678_3	379066.GAU_3913	7.621e-112	372.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS2_k127_5843678_9	861299.J421_0906	5.357e-30	126.0	2FFVA@1|root,347SB@2|Bacteria,1ZTX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5843678_4	861299.J421_0907	3.556e-109	357.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5843678_6	861299.J421_0908	3.21e-80	271.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_5843678_2	861299.J421_0915	1.017e-138	455.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5843678_1	861299.J421_0916	1.28e-188	605.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5843678_8	1541065.JRFE01000004_gene5334	1.74e-30	132.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,3VJ50@52604|Pleurocapsales	1117|Cyanobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,PhoPQ_related
GDHHQS2_k127_5855158_6	1038859.AXAU01000026_gene2342	1.993e-20	94.0	COG3795@1|root,COG3795@2|Bacteria,1RH6U@1224|Proteobacteria,2U5GH@28211|Alphaproteobacteria,3JY8B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS2_k127_5855158_1	1192034.CAP_5993	2.585e-59	206.0	COG0640@1|root,COG0640@2|Bacteria,1RGYC@1224|Proteobacteria,43A8G@68525|delta/epsilon subdivisions,2X2F4@28221|Deltaproteobacteria,2Z0IN@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_5855158_0	448385.sce6313	1.836e-75	255.0	COG3832@1|root,COG3832@2|Bacteria,1RA7N@1224|Proteobacteria,4390C@68525|delta/epsilon subdivisions,2X45E@28221|Deltaproteobacteria,2Z00U@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_5855158_4	1122604.JONR01000001_gene1860	1.082e-27	116.0	2E54V@1|root,32ZXS@2|Bacteria,1N6QG@1224|Proteobacteria,1SUWW@1236|Gammaproteobacteria,1X8X7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5855158_2	1123242.JH636436_gene366	5.929e-55	200.0	COG5649@1|root,COG5649@2|Bacteria,2IYNG@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_5855158_5	1122176.KB903537_gene1604	1.205e-26	117.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
GDHHQS2_k127_5855158_3	468059.AUHA01000002_gene1379	2.094e-38	153.0	COG0500@1|root,COG2226@2|Bacteria,4NNDT@976|Bacteroidetes,1IRYR@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_5857166_8	861299.J421_3835	1.601e-59	210.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_5857166_6	935837.JAEK01000022_gene1125	1.469e-73	256.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1ZCQT@1386|Bacillus	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
GDHHQS2_k127_5857166_4	861299.J421_3834	9.595e-92	310.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS2_k127_5857166_7	861299.J421_3833	2.993e-68	240.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS2_k127_5857166_5	1379270.AUXF01000003_gene3576	5.359e-88	301.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS2_k127_5857166_3	379066.GAU_2350	2.655e-103	363.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5857166_0	861299.J421_3828	0.0	1250.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS2_k127_5857166_1	861299.J421_3827	6.758e-221	691.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS2_k127_5857166_11	1379270.AUXF01000003_gene3591	3.086e-35	137.0	COG0228@1|root,COG0228@2|Bacteria,1ZTWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S16	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS2_k127_5857166_10	861299.J421_3825	4.491e-36	148.0	COG0806@1|root,COG0806@2|Bacteria,1ZU43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS2_k127_5857166_2	379066.GAU_2332	5.994e-106	347.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS2_k127_5857166_14	443152.MDG893_03545	5.504e-06	54.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,46BZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5857166_13	377629.TERTU_0630	4.771e-06	55.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,2PPQT@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5857166_9	861299.J421_3822	2.585e-56	199.0	COG0335@1|root,COG0335@2|Bacteria,1ZTUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS2_k127_5857166_12	379066.GAU_2295	3.857e-26	111.0	COG0164@1|root,COG0164@2|Bacteria,1ZTHY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS2_k127_5882612_4	861299.J421_4175	2.182e-23	108.0	COG3794@1|root,COG3794@2|Bacteria,1ZTXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_5882612_0	861299.J421_2451	1.64e-221	700.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_5882612_3	596152.DesU5LDRAFT_2637	3.586e-28	126.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2WPUI@28221|Deltaproteobacteria,2MAQQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1
GDHHQS2_k127_5882612_1	861299.J421_4178	7.265e-163	521.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GDHHQS2_k127_5882612_2	861299.J421_4179	1.602e-51	189.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_591229_1	861299.J421_2997	2.054e-227	721.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS2_k127_591229_2	861299.J421_2996	4.882e-61	235.0	2FBQ3@1|root,343V1@2|Bacteria,1ZU1R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS2_k127_591229_0	861299.J421_2994	0.0	1069.0	COG0525@1|root,COG0525@2|Bacteria,1ZSXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS2_k127_5916232_3	861299.J421_2732	5.063e-75	254.0	COG1024@1|root,COG1024@2|Bacteria,1ZT76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS2_k127_5916232_0	861299.J421_2731	2.309e-140	456.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GDHHQS2_k127_5916232_5	743720.Psefu_1217	1.402e-49	182.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,1S6E4@1236|Gammaproteobacteria,1YXI0@136845|Pseudomonas putida group	1236|Gammaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS2_k127_5916232_6	452637.Oter_1309	5.16e-45	167.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
GDHHQS2_k127_5916232_2	886293.Sinac_3436	5.154e-86	291.0	COG3228@1|root,COG3228@2|Bacteria,2IZES@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
GDHHQS2_k127_5916232_1	290397.Adeh_0051	1.173e-94	316.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
GDHHQS2_k127_5916232_4	379066.GAU_3212	3.195e-61	218.0	COG0006@1|root,COG0006@2|Bacteria,1ZUGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
GDHHQS2_k127_5958580_1	525897.Dbac_1184	2.487e-170	545.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
GDHHQS2_k127_5958580_0	861299.J421_6152	0.0	3280.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS2_k127_5958580_7	1123248.KB893370_gene5112	7.16e-32	136.0	COG2120@1|root,COG2120@2|Bacteria,4P6M2@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_5958580_4	153948.NAL212_2209	1.286e-61	229.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
GDHHQS2_k127_5958580_3	861299.J421_0860	4.144e-63	222.0	COG2353@1|root,COG2353@2|Bacteria,1ZV1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_5958580_6	469371.Tbis_2088	2.858e-32	131.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4E5MM@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GDHHQS2_k127_5958580_5	861299.J421_0893	1.814e-60	211.0	COG0780@1|root,COG0780@2|Bacteria,1ZTKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GDHHQS2_k127_5958580_2	379066.GAU_3894	8.169e-67	237.0	COG0705@1|root,COG0705@2|Bacteria,1ZSWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_5964514_1	861299.J421_3346	2.662e-268	836.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS2_k127_5964514_2	861299.J421_3345	2.214e-242	757.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS2_k127_5964514_4	861299.J421_3344	3.45e-54	192.0	2CIU6@1|root,32S8H@2|Bacteria,1ZTUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5964514_5	1267534.KB906755_gene4755	1.052e-46	181.0	COG1024@1|root,COG1024@2|Bacteria,3Y3SE@57723|Acidobacteria,2JIII@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_5964514_3	661478.OP10G_0723	8.937e-96	322.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_5964514_0	861299.J421_3341	5.397e-275	861.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
GDHHQS2_k127_5964514_6	1379270.AUXF01000004_gene3139	2.699e-42	159.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5973902_0	861299.J421_4070	6.709e-314	970.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
GDHHQS2_k127_5973902_6	861299.J421_4072	1.328e-47	177.0	COG2010@1|root,COG2010@2|Bacteria,1ZU6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
GDHHQS2_k127_5973902_8	1197906.CAJQ02000047_gene4077	3.997e-23	103.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5973902_3	861299.J421_4220	9.041e-110	365.0	COG2367@1|root,COG2367@2|Bacteria,1ZT83@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS2_k127_5973902_4	756067.MicvaDRAFT_0903	1.087e-71	250.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE2,HAMP,PAS,PAS_9,SpoIIE,dCache_1
GDHHQS2_k127_5973902_10	1266925.JHVX01000002_gene754	3.341e-16	87.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,373S6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
GDHHQS2_k127_5973902_5	756067.MicvaDRAFT_2416	1.188e-67	237.0	COG0546@1|root,COG0546@2|Bacteria,1G1NK@1117|Cyanobacteria,1H8PP@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_5973902_7	1268072.PSAB_16215	1.664e-33	134.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_5973902_1	861299.J421_1944	3.67e-221	700.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
GDHHQS2_k127_5973902_2	929556.Solca_3465	1.535e-219	690.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_5982358_0	1234364.AMSF01000085_gene2934	1.937e-172	554.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,1X3Q6@135614|Xanthomonadales	135614|Xanthomonadales	E	Dipeptidyl carboxypeptidase	dcp2	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS2_k127_5982358_2	1245469.S58_42410	3.284e-05	48.0	2AFMZ@1|root,313VJ@2|Bacteria,1N8AX@1224|Proteobacteria,2UH2P@28211|Alphaproteobacteria,3K1GV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5982358_1	1041930.Mtc_1962	1.554e-28	120.0	COG0526@1|root,arCOG01976@2157|Archaea	2157|Archaea	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	TPR_16,Thioredoxin_2,Thioredoxin_7
GDHHQS2_k127_6038146_4	1379270.AUXF01000001_gene2822	1.811e-25	116.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_6038146_1	861299.J421_4162	3.366e-126	426.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS2_k127_6038146_0	861299.J421_4163	5.882e-140	454.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS2_k127_6038146_2	861299.J421_4164	5.29e-93	316.0	COG0767@1|root,COG0767@2|Bacteria,1ZSUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS2_k127_6038146_3	1379270.AUXF01000001_gene2817	2.1e-70	252.0	COG1463@1|root,COG1463@2|Bacteria,1ZTI5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS2_k127_6060681_2	379066.GAU_1079	8.732e-42	158.0	COG1228@1|root,COG1228@2|Bacteria,1ZSME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_6060681_0	1132509.C447_09085	5.321e-136	440.0	COG0451@1|root,arCOG03019@2157|Archaea,2XVZH@28890|Euryarchaeota,23U95@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_6060681_3	1123256.KB907925_gene1491	3.181e-10	69.0	COG3453@1|root,COG3453@2|Bacteria,1N919@1224|Proteobacteria,1SEMT@1236|Gammaproteobacteria,1X8A2@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
GDHHQS2_k127_6060681_1	398527.Bphyt_4138	5.405e-80	267.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VKRT@28216|Betaproteobacteria,1K4CU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS2_k127_6088842_2	234267.Acid_5562	1.022e-44	164.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_6088842_0	861299.J421_2344	3.545e-257	810.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS2_k127_6088842_1	1379270.AUXF01000002_gene1787	1.391e-63	226.0	COG0726@1|root,COG0726@2|Bacteria,1ZSTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS2_k127_6095008_0	1121920.AUAU01000027_gene1480	5.11e-172	570.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000027_gene1480|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6111530_2	861299.J421_2968	1.107e-59	217.0	COG1947@1|root,COG1947@2|Bacteria,1ZTM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
GDHHQS2_k127_6111530_0	861299.J421_2969	9.782e-97	326.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_6111530_3	861299.J421_2970	1.748e-24	113.0	2CB0K@1|root,343GC@2|Bacteria,1ZU4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
GDHHQS2_k127_6111530_1	379066.GAU_1247	1.725e-91	306.0	COG0854@1|root,COG0854@2|Bacteria,1ZSPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
GDHHQS2_k127_6111530_4	379066.GAU_1248	8.539e-07	55.0	28ZEQ@1|root,2ZM6A@2|Bacteria,1ZU2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6195261_7	997346.HMPREF9374_2151	5.053e-58	218.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS2_k127_6195261_6	861299.J421_0063	6.812e-103	347.0	COG3842@1|root,COG3842@2|Bacteria,1ZU03@142182|Gemmatimonadetes	2|Bacteria	E	ABC transporter	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_6195261_5	1329516.JPST01000003_gene1164	1.576e-113	378.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HABY@91061|Bacilli,27CM5@186824|Thermoactinomycetaceae	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
GDHHQS2_k127_6195261_2	861299.J421_0065	3.637e-217	699.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_6195261_1	379066.GAU_0390	0.0	1155.0	COG0567@1|root,COG0567@2|Bacteria,1ZSVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
GDHHQS2_k127_6195261_3	861299.J421_0068	8.141e-159	514.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
GDHHQS2_k127_6195261_8	861299.J421_0069	1.119e-54	201.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS2_k127_6195261_4	861299.J421_0070	9.298e-135	435.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GDHHQS2_k127_6195261_0	861299.J421_0071	0.0	1350.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	2.7.13.3	ko:K03407,ko:K12257	ko02020,ko02024,ko02030,ko03060,ko03070,map02020,map02024,map02030,map03060,map03070	M00335,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	2.A.6.4	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_629003_0	1379270.AUXF01000001_gene2822	0.0	1753.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_629003_4	1434325.AZQN01000003_gene1924	2.519e-56	209.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_629003_3	379066.GAU_0426	5.947e-136	443.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_629003_5	861299.J421_4159	2.348e-24	108.0	COG1555@1|root,COG1555@2|Bacteria,1ZV96@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS2_k127_629003_1	861299.J421_4158	1.114e-277	865.0	COG2804@1|root,COG2804@2|Bacteria,1ZSSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS2_k127_629003_2	861299.J421_4157	7.43e-156	497.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS2_k127_6380625_4	1042163.BRLA_c006640	4.694e-48	186.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,26T5Z@186822|Paenibacillaceae	91061|Bacilli	E	Glycine oxidase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS2_k127_6380625_1	1379270.AUXF01000004_gene3127	7.105e-174	548.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS2_k127_6380625_2	861299.J421_2668	2.726e-145	472.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS2_k127_6380625_0	379066.GAU_0749	8.391e-175	557.0	COG0022@1|root,COG0022@2|Bacteria,1ZTA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_6380625_3	1242864.D187_006054	1.777e-90	313.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42RDN@68525|delta/epsilon subdivisions,2WMR0@28221|Deltaproteobacteria,2YUAJ@29|Myxococcales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_6405759_6	198467.NP92_00120	4.11e-89	303.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,21V76@150247|Anoxybacillus	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_6405759_3	861299.J421_3180	1.938e-191	619.0	COG0064@1|root,COG0064@2|Bacteria,1ZTCB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS2_k127_6405759_4	861299.J421_3181	1.961e-129	421.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
GDHHQS2_k127_6405759_12	1379270.AUXF01000005_gene816	1e-13	79.0	2A100@1|root,30P5D@2|Bacteria,1ZUX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6405759_2	114615.BRADO0005	2.397e-208	656.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,3JVEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS2_k127_6405759_7	861299.J421_3184	1.383e-82	281.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS2_k127_6405759_5	861299.J421_5728	9.261e-122	415.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_6405759_8	1379270.AUXF01000005_gene819	7.852e-41	155.0	COG0779@1|root,COG0779@2|Bacteria,1ZTX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
GDHHQS2_k127_6405759_0	1379270.AUXF01000005_gene820	2.465e-216	682.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
GDHHQS2_k127_6405759_10	861299.J421_3187	1.443e-26	112.0	COG1358@1|root,COG1358@2|Bacteria,1ZU1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
GDHHQS2_k127_6405759_1	518766.Rmar_1309	2.533e-215	698.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1FIVX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GDHHQS2_k127_6405759_9	1379270.AUXF01000005_gene823	1.572e-36	141.0	COG0858@1|root,COG0858@2|Bacteria,1ZTWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS2_k127_6405759_11	1382359.JIAL01000001_gene2819	3.784e-20	95.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria,2JIGA@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
GDHHQS2_k127_6411878_2	861299.J421_2677	1.151e-89	308.0	COG4775@1|root,COG4775@2|Bacteria,1ZTG1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6411878_3	1090319.KE386571_gene2121	3.027e-25	114.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS2_k127_6411878_0	861299.J421_2678	4.539e-203	644.0	COG3104@1|root,COG3104@2|Bacteria,1ZSRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GDHHQS2_k127_6411878_1	861299.J421_2679	3.897e-175	554.0	COG4608@1|root,COG4608@2|Bacteria,1ZSTB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_6426323_0	861299.J421_2541	1.14e-209	664.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_6426323_1	861299.J421_2540	3.97e-146	467.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_6435461_10	861299.J421_2907	5.946e-36	154.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS2_k127_6435461_9	861299.J421_2906	2.748e-83	286.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_6435461_6	861299.J421_2904	3.044e-124	415.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS2_k127_6435461_3	379066.GAU_1147	3.058e-156	503.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GDHHQS2_k127_6435461_5	1379270.AUXF01000005_gene457	1.906e-134	434.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6435461_4	379066.GAU_3472	1.234e-154	505.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6435461_0	379066.GAU_3473	2.492e-180	578.0	COG0577@1|root,COG0577@2|Bacteria,1ZT67@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6435461_7	861299.J421_6166	3.982e-105	353.0	COG0628@1|root,COG0628@2|Bacteria,1ZSY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS2_k127_6435461_1	861299.J421_1415	2.418e-176	561.0	COG0577@1|root,COG0577@2|Bacteria,1ZUG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6435461_2	1379270.AUXF01000005_gene449	6.736e-164	529.0	COG0577@1|root,COG0577@2|Bacteria,1ZUCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_6435461_8	861299.J421_2896	1.534e-84	284.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS2_k127_6437472_0	379066.GAU_2144	7.366e-314	969.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_6437472_1	1089552.KI911559_gene1481	4.912e-74	266.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,2JRGG@204441|Rhodospirillales	204441|Rhodospirillales	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS2_k127_6437472_2	861299.J421_3989	9.751e-64	230.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_6447840_10	861299.J421_3587	4.927e-15	75.0	COG1027@1|root,COG1027@2|Bacteria,1ZSUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS2_k127_6447840_3	379066.GAU_1983	5.181e-70	240.0	COG1959@1|root,COG1959@2|Bacteria,1ZTRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS2_k127_6447840_5	861299.J421_1728	1.28e-64	238.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_6447840_8	861299.J421_3584	3.612e-59	208.0	COG0691@1|root,COG0691@2|Bacteria,1ZTQN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS2_k127_6447840_0	1379270.AUXF01000003_gene3876	3.294e-99	339.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS2_k127_6447840_1	861299.J421_3582	1.257e-97	325.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS2_k127_6447840_4	1379270.AUXF01000003_gene3879	5.289e-69	242.0	COG0284@1|root,COG0284@2|Bacteria,1ZTQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS2_k127_6447840_9	379066.GAU_1977	3.261e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS2_k127_6447840_6	1379270.AUXF01000003_gene3880	2.532e-62	217.0	COG0099@1|root,COG0099@2|Bacteria,1ZTNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS2_k127_6447840_7	1379270.AUXF01000003_gene3881	2.892e-62	219.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS2_k127_6447840_2	861299.J421_3577	2.095e-89	296.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS2_k127_6450247_4	1122604.JONR01000067_gene4214	3.271e-73	256.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1X6I7@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
GDHHQS2_k127_6450247_6	861299.J421_2106	1.199e-43	161.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
GDHHQS2_k127_6450247_9	861299.J421_2103	7.121e-34	137.0	COG1534@1|root,COG1534@2|Bacteria,1ZU26@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
GDHHQS2_k127_6450247_8	1379270.AUXF01000001_gene2399	1.141e-35	144.0	COG0739@1|root,COG0739@2|Bacteria,1ZTXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS2_k127_6450247_1	1487953.JMKF01000043_gene2596	1.067e-196	625.0	COG0422@1|root,COG0422@2|Bacteria,1G2N9@1117|Cyanobacteria,1H931@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
GDHHQS2_k127_6450247_13	1207075.PputUW4_01882	8.574e-08	59.0	2E3S2@1|root,32YPN@2|Bacteria,1NDK1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6450247_10	682795.AciX8_1075	3.074e-23	107.0	COG1476@1|root,COG1476@2|Bacteria,3Y5P8@57723|Acidobacteria,2JJXV@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS2_k127_6450247_5	861299.J421_2835	6.304e-65	233.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6450247_7	1379270.AUXF01000001_gene2240	1.248e-36	147.0	COG4875@1|root,COG4875@2|Bacteria,1ZTYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GDHHQS2_k127_6450247_11	1396141.BATP01000051_gene3338	2.68e-17	85.0	2EKH8@1|root,33E79@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6450247_14	383372.Rcas_2521	2.897e-07	59.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_6450247_2	861299.J421_2088	8.171e-133	443.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_6450247_3	1379270.AUXF01000001_gene2395	5.952e-125	406.0	COG0396@1|root,COG0396@2|Bacteria,1ZSRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS2_k127_6450247_0	861299.J421_2090	2.167e-241	749.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_6452056_0	861299.J421_3231	1.117e-252	789.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
GDHHQS2_k127_6452056_3	861299.J421_3230	2.902e-170	556.0	COG0728@1|root,COG0728@2|Bacteria,1ZTCM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS2_k127_6452056_4	861299.J421_3229	6.159e-141	464.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
GDHHQS2_k127_6452056_11	1118054.CAGW01000016_gene4534	9.77e-53	195.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HGZ2@91061|Bacilli,26SJY@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_6452056_12	379066.GAU_1595	1.3e-51	186.0	COG1576@1|root,COG1576@2|Bacteria,1ZTQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
GDHHQS2_k127_6452056_1	861299.J421_3227	4.727e-226	706.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS2_k127_6452056_9	861299.J421_3226	2.292e-87	299.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
GDHHQS2_k127_6452056_13	1379270.AUXF01000006_gene296	3.564e-45	173.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
GDHHQS2_k127_6452056_5	861299.J421_3224	1.018e-135	441.0	COG0763@1|root,COG0763@2|Bacteria,1ZTAD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS2_k127_6452056_6	861299.J421_3223	1.864e-128	419.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6452056_8	861299.J421_3222	1.197e-108	357.0	COG1043@1|root,COG1043@2|Bacteria,1ZT7T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GDHHQS2_k127_6452056_2	861299.J421_3221	7.314e-187	591.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
GDHHQS2_k127_6452056_7	861299.J421_3220	3.397e-113	376.0	COG1044@1|root,COG1044@2|Bacteria,1ZSRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS2_k127_6452056_14	379066.GAU_1586	2.927e-29	126.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
GDHHQS2_k127_6452056_10	379066.GAU_1585	6.205e-78	265.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS2_k127_6452534_3	861299.J421_3619	1.007e-66	230.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_6452534_6	861299.J421_3618	1.811e-35	144.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_6452534_2	861299.J421_3618	9.412e-77	263.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS2_k127_6452534_1	861299.J421_3617	9.651e-116	376.0	COG0811@1|root,COG0811@2|Bacteria,1ZTH1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS2_k127_6452534_5	1379270.AUXF01000003_gene3846	1.904e-47	175.0	COG0848@1|root,COG0848@2|Bacteria,1ZTTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS2_k127_6452534_7	279238.Saro_0014	3.749e-05	51.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS2_k127_6452534_4	861299.J421_3614	8.353e-48	182.0	2C803@1|root,33Q52@2|Bacteria,1ZTK6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6452534_0	204669.Acid345_3285	6.295e-157	510.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS2_k127_6464487_0	1379270.AUXF01000001_gene2613	2.773e-120	395.0	COG0467@1|root,COG0467@2|Bacteria,1ZUWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS2_k127_6464487_1	861299.J421_2721	1.168e-88	314.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_2721|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6464487_2	861299.J421_5614	4.757e-79	267.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GDHHQS2_k127_6476651_2	861299.J421_6361	9.208e-13	79.0	2F5SD@1|root,33YB8@2|Bacteria,1ZUXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6476651_3	382464.ABSI01000013_gene1773	7.027e-05	55.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6476651_0	861299.J421_3620	9.824e-112	365.0	COG0745@1|root,COG0745@2|Bacteria,1ZT8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_6476651_1	861299.J421_3619	1.238e-55	207.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_6478215_0	861299.J421_2748	0.0	1103.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS2_k127_6478215_4	161528.ED21_20779	5.839e-22	109.0	2FGC9@1|root,3488G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
GDHHQS2_k127_6478215_5	1123278.KB893398_gene4245	2.642e-21	106.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,47NSY@768503|Cytophagia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
GDHHQS2_k127_6478215_3	1242864.D187_005262	9.178e-75	265.0	COG1409@1|root,COG1409@2|Bacteria,1RJ6Z@1224|Proteobacteria	1224|Proteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_6478215_1	861299.J421_3843	6.144e-195	621.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1ZTH0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FPT	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GDHHQS2_k127_6478215_2	379066.GAU_2372	8.753e-139	447.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS2_k127_6489381_3	861299.J421_6256	7.308e-67	256.0	COG0515@1|root,COG0515@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
GDHHQS2_k127_6489381_7	861299.J421_0886	5.684e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,1ZUWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_6489381_5	926554.KI912671_gene275	3.683e-56	209.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
GDHHQS2_k127_6489381_6	926554.KI912671_gene275	5.278e-52	187.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
GDHHQS2_k127_6489381_2	861299.J421_3773	1.23e-72	257.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_6489381_0	861299.J421_4469	0.0	1057.0	COG1913@1|root,COG1913@2|Bacteria,1ZT1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
GDHHQS2_k127_6489381_1	1123508.JH636439_gene1853	6.477e-147	499.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_6489381_4	379066.GAU_2548	6.438e-64	231.0	COG4772@1|root,COG4772@2|Bacteria,1ZT8H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_6493994_0	234267.Acid_6465	2.397e-141	464.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS2_k127_6493994_3	402626.Rpic_4115	5.109e-59	213.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,1K5JG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GDHHQS2_k127_6493994_4	1279009.ADICEAN_03673	6.938e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,4P4RR@976|Bacteroidetes	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_6493994_1	661367.LLO_0670	1.397e-111	387.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1JC52@118969|Legionellales	118969|Legionellales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS2_k127_6493994_2	1379270.AUXF01000001_gene2417	3.693e-76	265.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS2_k127_6493994_5	1282362.AEAC466_02495	2e-46	170.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,2U30K@28211|Alphaproteobacteria,2KG2G@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
GDHHQS2_k127_6516385_6	861299.J421_2362	1.132e-75	261.0	COG0277@1|root,COG0277@2|Bacteria,1ZTB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS2_k127_6516385_3	671143.DAMO_2551	9.74e-103	342.0	COG1250@1|root,COG1250@2|Bacteria,2NP11@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_6516385_10	861299.J421_2367	1.032e-47	182.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6516385_4	861299.J421_2368	2.723e-95	325.0	2EXE5@1|root,33QQP@2|Bacteria,1ZTI3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6516385_2	1192034.CAP_5365	4.53e-131	437.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_6516385_11	861299.J421_2370	1.008e-33	138.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6516385_8	861299.J421_2372	1.19e-68	239.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GDHHQS2_k127_6516385_13	861299.J421_2373	8.043e-18	84.0	28UVI@1|root,2ZGZI@2|Bacteria,1ZU6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6516385_0	861299.J421_2374	1.434e-141	458.0	COG0624@1|root,COG0624@2|Bacteria,1ZSZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_6516385_12	861299.J421_2378	3.318e-31	130.0	2F43E@1|root,33WUY@2|Bacteria,1ZTT4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6516385_1	861299.J421_2379	1.528e-139	451.0	COG1804@1|root,COG1804@2|Bacteria,1ZT8E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS2_k127_6516385_7	861299.J421_1544	2.648e-73	262.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	envE	-	3.1.4.46,3.2.1.18,3.2.1.8	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	-	R01030,R01470,R04018	RC00017,RC00028,RC00077,RC00425	ko00000,ko00001,ko01000,ko02042	-	GH33	-	GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH
GDHHQS2_k127_6516385_9	927658.AJUM01000021_gene968	5.473e-49	188.0	COG0863@1|root,COG3392@1|root,COG0863@2|Bacteria,COG3392@2|Bacteria,4PIKF@976|Bacteroidetes,2G1FK@200643|Bacteroidia,3XM01@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GDHHQS2_k127_6516385_5	379066.GAU_0474	3.142e-82	285.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_6551494_32	926549.KI421517_gene3612	8.566e-17	81.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,47MR9@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS2_k127_6551494_6	861299.J421_1132	1.604e-197	622.0	COG0673@1|root,COG0673@2|Bacteria,1ZSVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_6551494_35	1379270.AUXF01000003_gene3750	0.0009642	46.0	COG1629@1|root,COG4219@1|root,COG1629@2|Bacteria,COG4219@2|Bacteria,1ZUHU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KPT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
GDHHQS2_k127_6551494_31	661478.OP10G_1457	6.442e-25	110.0	COG3668@1|root,32ZH9@2|Bacteria	2|Bacteria	S	COG3668 Plasmid stabilization system protein	osmB	-	-	-	-	-	-	-	-	-	-	-	Rho_N
GDHHQS2_k127_6551494_4	443144.GM21_2279	2.925e-232	751.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,42M4M@68525|delta/epsilon subdivisions,2WIPI@28221|Deltaproteobacteria,43SU8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS2_k127_6551494_20	1121920.AUAU01000004_gene852	1.63e-61	224.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria	57723|Acidobacteria	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS2_k127_6551494_25	1278073.MYSTI_01758	3.514e-49	194.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
GDHHQS2_k127_6551494_17	414684.RC1_3385	4.457e-78	267.0	COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,2U5E8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS2_k127_6551494_30	861299.J421_4416	4.659e-29	119.0	COG2261@1|root,COG2261@2|Bacteria,1ZV7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_6551494_29	469383.Cwoe_3468	1.044e-37	148.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052,OmdA
GDHHQS2_k127_6551494_19	379066.GAU_0437	8.776e-70	248.0	COG0124@1|root,COG0124@2|Bacteria,1ZTTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6551494_7	118163.Ple7327_0424	1.897e-171	550.0	COG0179@1|root,COG0179@2|Bacteria,1G2C6@1117|Cyanobacteria,3VHWU@52604|Pleurocapsales	1117|Cyanobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
GDHHQS2_k127_6551494_22	215803.DB30_3560	4.046e-54	194.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,438IX@68525|delta/epsilon subdivisions,2X3TU@28221|Deltaproteobacteria,2YX3A@29|Myxococcales	28221|Deltaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS2_k127_6551494_5	1227739.Hsw_0942	5.558e-214	684.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
GDHHQS2_k127_6551494_26	861299.J421_3698	5.144e-46	176.0	COG2967@1|root,COG2967@2|Bacteria,1ZTR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
GDHHQS2_k127_6551494_23	443144.GM21_3621	1.055e-52	195.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS2_k127_6551494_28	319795.Dgeo_1667	7.947e-43	168.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS2_k127_6551494_10	479434.Sthe_2435	1.702e-120	393.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS2_k127_6551494_8	316274.Haur_3021	1.415e-164	536.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS2_k127_6551494_27	309801.trd_1531	3.353e-43	179.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
GDHHQS2_k127_6551494_18	861299.J421_3040	1.185e-71	253.0	COG0037@1|root,COG0037@2|Bacteria,1ZTK2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
GDHHQS2_k127_6551494_16	1379270.AUXF01000005_gene655	3.213e-87	292.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS2_k127_6551494_0	861299.J421_3042	7.423e-320	991.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
GDHHQS2_k127_6551494_14	861299.J421_3043	1.131e-87	300.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
GDHHQS2_k127_6551494_9	861299.J421_3046	3.239e-128	428.0	COG0659@1|root,COG2976@1|root,COG0659@2|Bacteria,COG2976@2|Bacteria	2|Bacteria	CO	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21,TPR_6,TPR_8
GDHHQS2_k127_6551494_2	861299.J421_2862	2.681e-261	811.0	COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS2_k127_6551494_13	861299.J421_2861	1.03e-89	306.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
GDHHQS2_k127_6551494_12	861299.J421_3437	2.187e-93	318.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_6551494_1	861299.J421_3436	1.862e-301	935.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GDHHQS2_k127_6551494_11	861299.J421_3435	1.825e-112	381.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS2_k127_6551494_3	861299.J421_3434	1.385e-232	736.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS2_k127_6551494_24	1379270.AUXF01000006_gene97	3.088e-49	196.0	2C3N7@1|root,33YDV@2|Bacteria,1ZTRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6551494_15	861299.J421_5728	1.582e-87	316.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_6567230_2	861299.J421_2451	1.294e-130	422.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_6567230_3	861299.J421_4175	6.379e-47	181.0	COG3794@1|root,COG3794@2|Bacteria,1ZTXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6567230_0	861299.J421_4174	1.478e-223	719.0	COG1132@1|root,COG1132@2|Bacteria,1ZSP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_6567230_1	861299.J421_4172	3.437e-139	447.0	COG0109@1|root,COG0109@2|Bacteria,1ZSP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS2_k127_6567230_4	379066.GAU_2580	1.688e-24	109.0	COG1612@1|root,COG1612@2|Bacteria,1ZURE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS2_k127_6572707_3	379066.GAU_0986	1.317e-26	114.0	COG1413@1|root,COG1413@2|Bacteria,1ZUDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_6572707_0	861299.J421_6191	1.245e-128	426.0	COG1413@1|root,COG1413@2|Bacteria,1ZUDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_6572707_2	1144275.COCOR_01812	1.941e-57	214.0	COG1680@1|root,COG1680@2|Bacteria,1RGG3@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6572707_1	1379270.AUXF01000001_gene2272	2.075e-104	348.0	COG1524@1|root,COG1524@2|Bacteria,1ZUMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_6594740_3	379066.GAU_1687	2.157e-63	226.0	COG1573@1|root,COG1573@2|Bacteria,1ZTG5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_6594740_0	861299.J421_3319	3.119e-154	503.0	COG0452@1|root,COG0452@2|Bacteria,1ZV19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS2_k127_6594740_4	1379270.AUXF01000006_gene203	1.827e-25	106.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
GDHHQS2_k127_6594740_2	379066.GAU_1689	8.499e-74	256.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS2_k127_6594740_1	861299.J421_3322	7.007e-92	310.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GDHHQS2_k127_6607351_0	861299.J421_2908	1.111e-215	689.0	COG0515@1|root,COG0515@2|Bacteria,1ZTB4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6607351_1	1379270.AUXF01000005_gene461	5.916e-142	474.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS2_k127_6645013_10	1232410.KI421412_gene169	1.424e-15	77.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS2_k127_6645013_0	667632.KB890217_gene4863	3.193e-221	708.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,1K0BX@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_6645013_4	867903.ThesuDRAFT_01226	2.36e-102	338.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,3WD8B@538999|Clostridiales incertae sedis	186801|Clostridia	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
GDHHQS2_k127_6645013_5	1121904.ARBP01000017_gene5069	5.796e-84	289.0	2CK9T@1|root,2Z7W9@2|Bacteria,4NH9E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6645013_6	1122605.KB893646_gene195	4.139e-70	250.0	2B33H@1|root,31VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6645013_8	158189.SpiBuddy_2575	8.175e-34	141.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS2_k127_6645013_1	379066.GAU_0476	8.948e-218	683.0	COG1249@1|root,COG1249@2|Bacteria,1ZTF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_6645013_2	379066.GAU_0480	1.099e-165	530.0	COG0508@1|root,COG0508@2|Bacteria,1ZTB5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_6645013_3	861299.J421_2390	3.296e-147	473.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_6645013_9	861299.J421_2391	5.293e-21	97.0	28TV6@1|root,2ZG24@2|Bacteria,1ZV98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6645013_7	379066.GAU_1264	2.453e-37	154.0	2AEWW@1|root,314UI@2|Bacteria,1ZUPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6647773_1	207559.Dde_1357	9.552e-55	196.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2MBJG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS2_k127_6647773_0	99598.Cal7507_2182	2.975e-275	866.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1HJE5@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_6647773_2	861299.J421_2472	1.516e-48	181.0	COG0762@1|root,COG0762@2|Bacteria,1ZTUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS2_k127_6647773_3	522306.CAP2UW1_3597	7.989e-16	88.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS2_k127_6654204_2	945713.IALB_1188	8.712e-70	238.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	lacF	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GDHHQS2_k127_6654204_1	743721.Psesu_1286	5.559e-102	340.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1S4G6@1236|Gammaproteobacteria,1X3NS@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_6654204_0	945713.IALB_1183	2.246e-173	571.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
GDHHQS2_k127_6660951_6	379066.GAU_3334	1.285e-82	280.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6660951_1	861299.J421_1931	5.694e-212	670.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GDHHQS2_k127_6660951_3	861299.J421_1849	1.579e-102	343.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_6660951_10	593907.Celgi_0128	4.684e-08	57.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS2_k127_6660951_4	1242864.D187_005528	1.239e-99	342.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6660951_0	404589.Anae109_1015	5.333e-275	859.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
GDHHQS2_k127_6660951_9	379066.GAU_1320	1.273e-30	126.0	COG4319@1|root,COG4319@2|Bacteria,1ZV6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6660951_8	234267.Acid_3868	1.322e-57	209.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS2_k127_6660951_7	1210884.HG799465_gene11339	3.887e-60	213.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_6660951_5	861299.J421_1374	8.639e-87	302.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd2	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
GDHHQS2_k127_6660951_2	869210.Marky_1927	1.279e-174	563.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS2_k127_6660951_11	861299.J421_6216	1.167e-07	60.0	COG1629@1|root,COG4771@2|Bacteria,1ZTA1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS2_k127_6669358_16	861299.J421_3268	3.011e-59	208.0	COG0304@1|root,COG0304@2|Bacteria,1ZSPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_6669358_20	861299.J421_3269	1.196e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1ZU0X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS2_k127_6669358_12	861299.J421_3270	3.326e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_6669358_11	861299.J421_3271	1.771e-116	386.0	COG0331@1|root,COG0331@2|Bacteria,1ZT40@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS2_k127_6669358_8	861299.J421_3272	1.201e-154	497.0	COG0332@1|root,COG0332@2|Bacteria,1ZSP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS2_k127_6669358_10	1379270.AUXF01000006_gene250	5.467e-131	426.0	COG0416@1|root,COG0416@2|Bacteria,1ZSN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS2_k127_6669358_23	861299.J421_3274	5.055e-25	104.0	COG0333@1|root,COG0333@2|Bacteria,1ZU2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS2_k127_6669358_18	861299.J421_3275	2.089e-50	184.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS2_k127_6669358_17	1379270.AUXF01000006_gene247	9.498e-56	197.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS2_k127_6669358_9	379066.GAU_1645	6.798e-147	472.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS2_k127_6669358_4	861299.J421_3279	4.48e-182	577.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS2_k127_6669358_15	1379698.RBG1_1C00001G0473	2.579e-72	259.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
GDHHQS2_k127_6669358_14	1379270.AUXF01000006_gene244	1.186e-82	297.0	COG1615@1|root,COG1615@2|Bacteria,1ZTEE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS2_k127_6669358_3	379066.GAU_1648	1.237e-198	635.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_6669358_7	861299.J421_3282	1.779e-170	548.0	COG1007@1|root,COG1007@2|Bacteria,1ZSVJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS2_k127_6669358_5	861299.J421_3283	2.973e-176	570.0	COG1008@1|root,COG1008@2|Bacteria,1ZUBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS2_k127_6669358_0	861299.J421_3284	5.646e-269	851.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS2_k127_6669358_22	1379270.AUXF01000006_gene239	1.505e-29	121.0	COG0713@1|root,COG0713@2|Bacteria,1ZU00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS2_k127_6669358_19	1379270.AUXF01000006_gene238	7.608e-47	174.0	COG0839@1|root,COG0839@2|Bacteria,1ZTSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS2_k127_6669358_13	861299.J421_3287	3.417e-92	304.0	COG1143@1|root,COG1143@2|Bacteria,1ZTHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
GDHHQS2_k127_6669358_6	861299.J421_3288	3.462e-173	552.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS2_k127_6669358_1	861299.J421_3289	3.804e-233	732.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1ZTDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GDHHQS2_k127_6669358_2	379066.GAU_1657	5.006e-224	702.0	COG1894@1|root,COG1894@2|Bacteria,1ZSQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS2_k127_6669358_21	1379270.AUXF01000006_gene233	3.063e-30	120.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS2_k127_6669499_1	761193.Runsl_2857	5.018e-71	244.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS2_k127_6669499_0	861299.J421_1672	3.527e-203	666.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS2_k127_6669499_2	1382315.JPOI01000001_gene2159	2.787e-42	163.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HDIK@91061|Bacilli,1WFN4@129337|Geobacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
GDHHQS2_k127_6694280_1	379066.GAU_2624	1.98e-22	100.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_6694280_2	379066.GAU_2624	4.838e-07	58.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_6694280_0	861299.J421_2036	5.227e-68	242.0	2EXQQ@1|root,33R07@2|Bacteria,1ZUK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6699465_0	861299.J421_2757	1.884e-220	691.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS2_k127_6699465_1	1403819.BATR01000112_gene3726	3.242e-28	124.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6703649_0	1396141.BATP01000044_gene1489	3.157e-231	721.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_6703649_2	1396141.BATP01000044_gene1487	2.487e-109	363.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_6703649_1	861299.J421_1729	6.324e-155	518.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6703649_3	1122137.AQXF01000004_gene1587	1.796e-35	147.0	COG2267@1|root,COG2267@2|Bacteria,1QWE3@1224|Proteobacteria,2UDWQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_6703649_4	861299.J421_3650	2e-09	63.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS2_k127_6710894_7	502025.Hoch_1576	8.852e-11	65.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS2_k127_6710894_2	41431.PCC8801_0005	4.46e-55	200.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GDHHQS2_k127_6710894_3	713586.KB900536_gene1207	2.39e-35	140.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,1S2PS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GDHHQS2_k127_6710894_1	234267.Acid_3612	1.004e-58	214.0	2E3HM@1|root,32W74@2|Bacteria,3Y85J@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6710894_6	649638.Trad_1432	6.526e-23	102.0	COG3093@1|root,COG3093@2|Bacteria,1WKRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG3093 Plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS2_k127_6710894_5	555779.Dthio_PD1883	4.278e-25	107.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS2_k127_6710894_4	999550.KI421507_gene350	9.479e-32	131.0	2A76B@1|root,30W2A@2|Bacteria,1RGCK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6710894_0	903818.KI912268_gene2312	7.534e-97	327.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_6722601_3	644282.Deba_3173	2.096e-90	307.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_6722601_5	861299.J421_3195	1.149e-40	156.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_6722601_4	1122147.AUEH01000024_gene1834	3.318e-45	173.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae	91061|Bacilli	L	hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS2_k127_6722601_2	861299.J421_3193	5.107e-115	379.0	COG0341@1|root,COG0341@2|Bacteria,1ZSSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_6722601_0	1379270.AUXF01000005_gene826	1.241e-218	691.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_6722601_1	861299.J421_3191	1.548e-119	392.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS2_k127_6722601_6	379066.GAU_1558	2.67e-29	121.0	COG0130@1|root,COG0130@2|Bacteria,1ZTJM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
GDHHQS2_k127_6759784_0	861299.J421_2545	1.571e-103	351.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS2_k127_6759784_3	861299.J421_2549	8.436e-61	221.0	COG0791@1|root,COG0791@2|Bacteria,1ZTVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
GDHHQS2_k127_6759784_4	1379270.AUXF01000004_gene3272	7.489e-42	158.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6759784_2	1379270.AUXF01000004_gene3271	1.43e-69	246.0	COG0697@1|root,COG0697@2|Bacteria,1ZTNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_6759784_1	861299.J421_2552	7.043e-82	292.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS2_k127_6759784_5	861299.J421_2553	8.82e-23	103.0	COG1437@1|root,COG1437@2|Bacteria	2|Bacteria	F	CYTH domain	mtaD	-	4.6.1.1	ko:K01768,ko:K05873	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
GDHHQS2_k127_6767595_5	861299.J421_1019	1.484e-106	350.0	COG1402@1|root,COG1402@2|Bacteria,1ZTKC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_6767595_0	379066.GAU_0518	0.0	1213.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS2_k127_6767595_6	1123239.KB898625_gene336	1.413e-23	115.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	mcpB1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
GDHHQS2_k127_6767595_2	379066.GAU_0517	5.882e-140	454.0	COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
GDHHQS2_k127_6767595_4	1166018.FAES_1629	2.228e-116	387.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
GDHHQS2_k127_6767595_1	861299.J421_2415	6.937e-225	710.0	COG1027@1|root,COG1027@2|Bacteria,1ZT1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
GDHHQS2_k127_6767595_3	861299.J421_2407	1.349e-122	407.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1ZT3S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS2_k127_6770982_14	926550.CLDAP_29100	2.885e-17	81.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS2_k127_6770982_3	861299.J421_3544	7.601e-164	520.0	COG0535@1|root,COG0535@2|Bacteria,1ZT6Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS2_k127_6770982_5	1379270.AUXF01000006_gene25	1.826e-152	494.0	COG1228@1|root,COG1228@2|Bacteria,1ZSNQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GDHHQS2_k127_6770982_8	861299.J421_3542	1.553e-68	260.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS2_k127_6770982_6	379066.GAU_1932	2.473e-113	382.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_6770982_11	379066.GAU_1931	5.047e-38	145.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
GDHHQS2_k127_6770982_13	379066.GAU_1930	6.906e-19	89.0	COG1826@1|root,COG1826@2|Bacteria,1ZU4N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS2_k127_6770982_1	861299.J421_3538	7.106e-209	665.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
GDHHQS2_k127_6770982_12	1379270.AUXF01000006_gene31	7.345e-38	161.0	COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_6770982_10	1379270.AUXF01000006_gene32	1.477e-49	186.0	COG0757@1|root,COG0757@2|Bacteria,1ZTVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GDHHQS2_k127_6770982_4	861299.J421_3535	6.191e-153	490.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_6770982_9	379066.GAU_1925	3.085e-64	224.0	COG0511@1|root,COG0511@2|Bacteria,1ZTR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS2_k127_6770982_2	1379270.AUXF01000006_gene35	1.015e-167	534.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS2_k127_6770982_0	861299.J421_3533	6.908e-248	769.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS2_k127_6770982_7	861299.J421_3532	1.01e-81	278.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
GDHHQS2_k127_6890643_4	861299.J421_3308	6.254e-49	191.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS2_k127_6890643_1	1379270.AUXF01000006_gene213	1.516e-168	537.0	COG0126@1|root,COG0126@2|Bacteria,1ZT1B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS2_k127_6890643_0	861299.J421_3310	1.791e-174	551.0	COG0057@1|root,COG0057@2|Bacteria,1ZSTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS2_k127_6890643_2	861299.J421_3311	1.237e-80	277.0	COG1040@1|root,COG1040@2|Bacteria,1ZTS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS2_k127_6890643_3	861299.J421_3312	1.282e-77	270.0	COG0169@1|root,COG0169@2|Bacteria,1ZTVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
GDHHQS2_k127_6890643_5	861299.J421_3313	2.427e-13	71.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS2_k127_6954663_3	1379270.AUXF01000002_gene1468	2.072e-74	254.0	COG0789@1|root,COG0789@2|Bacteria,1ZTHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_6954663_5	1379270.AUXF01000002_gene1469	1.382e-59	219.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_6954663_2	379066.GAU_0199	4.281e-121	400.0	COG3437@1|root,COG3437@2|Bacteria,1ZTD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
GDHHQS2_k127_6954663_0	379066.GAU_0200	3.02e-134	452.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1ZTAG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_6954663_1	861299.J421_0447	4.649e-132	426.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS2_k127_6954663_4	861299.J421_0446	1.439e-68	242.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6954663_6	861299.J421_0438	3.201e-52	188.0	COG3968@1|root,COG3968@2|Bacteria,1ZSPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
GDHHQS2_k127_6981844_1	379066.GAU_1166	1.316e-148	475.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_6981844_0	861299.J421_2920	1.203e-272	843.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS2_k127_6981844_2	861299.J421_2921	5.058e-66	231.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS2_k127_7000628_0	861299.J421_4436	1.054e-129	422.0	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GDHHQS2_k127_7000628_1	861299.J421_3550	5.855e-28	120.0	COG2885@1|root,COG2885@2|Bacteria,1ZTSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS2_k127_7000628_2	526225.Gobs_1610	4.76e-12	72.0	COG3631@1|root,COG3631@2|Bacteria,2GQBR@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS2_k127_7096137_3	861299.J421_1256	2.324e-72	250.0	COG2215@1|root,COG2215@2|Bacteria,1ZV92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7096137_1	861299.J421_3439	2.047e-122	406.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS2_k127_7096137_2	1379270.AUXF01000006_gene90	2.211e-106	352.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS2_k127_7096137_0	1379270.AUXF01000006_gene89	2.023e-244	764.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS2_k127_7096137_4	861299.J421_3442	2.023e-11	65.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GDHHQS2_k127_7122079_4	1379270.AUXF01000003_gene3892	6.428e-42	157.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS2_k127_7122079_1	861299.J421_0144	8.13e-194	612.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS2_k127_7122079_2	861299.J421_3568	1.047e-57	209.0	COG4105@1|root,COG4105@2|Bacteria,1ZTMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
GDHHQS2_k127_7122079_3	861299.J421_3567	3.298e-56	205.0	COG1057@1|root,COG1057@2|Bacteria,1ZTT1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS2_k127_7122079_0	861299.J421_3566	0.0	1564.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_7122079_5	861299.J421_3564	2.481e-21	97.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS2_k127_713351_2	379066.GAU_0011	4.994e-18	91.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS2_k127_713351_0	234267.Acid_7167	7.165e-234	752.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
GDHHQS2_k127_713351_3	1238182.C882_3875	9.01e-08	63.0	2EJPN@1|root,33DEG@2|Bacteria,1NJ0G@1224|Proteobacteria,2UKKF@28211|Alphaproteobacteria,2JUH8@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_713351_5	1121287.AUMU01000010_gene1805	1.336e-05	48.0	29EH7@1|root,301F5@2|Bacteria,4PGMM@976|Bacteroidetes,1IHES@117743|Flavobacteriia,3ZU3J@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_713351_1	861299.J421_2624	2.165e-27	114.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_7155363_4	1379270.AUXF01000006_gene276	3.212e-113	369.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_7155363_6	861299.J421_3244	3.444e-86	294.0	COG0253@1|root,COG0253@2|Bacteria,1ZU42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS2_k127_7155363_10	1379270.AUXF01000006_gene278	9.818e-31	131.0	COG2976@1|root,COG2976@2|Bacteria,1ZTZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS2_k127_7155363_12	1382356.JQMP01000003_gene2541	5.14e-13	78.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi,27YMW@189775|Thermomicrobia	189775|Thermomicrobia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS2_k127_7155363_5	861299.J421_3240	3.904e-97	323.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_7155363_2	861299.J421_3239	3.201e-127	413.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS2_k127_7155363_9	935567.JAES01000007_gene1848	5.308e-33	136.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,1S39Y@1236|Gammaproteobacteria,1XCJR@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_7155363_8	1379270.AUXF01000006_gene283	2.498e-47	174.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_7155363_3	379066.GAU_1603	2.664e-121	399.0	COG0240@1|root,COG0240@2|Bacteria,1ZTFK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS2_k127_7155363_7	861299.J421_3236	1.98e-62	220.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS2_k127_7155363_0	861299.J421_3235	7.053e-207	651.0	COG1160@1|root,COG1160@2|Bacteria,1ZSQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS2_k127_7155363_1	861299.J421_3234	7.676e-201	632.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
GDHHQS2_k127_7155363_11	861299.J421_3231	5.213e-19	87.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
GDHHQS2_k127_7162847_1	1122939.ATUD01000009_gene3064	1.507e-38	161.0	COG1413@1|root,COG1413@2|Bacteria,2IHYB@201174|Actinobacteria	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_7162847_0	1146883.BLASA_1780	2.2e-93	332.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
GDHHQS2_k127_7205153_0	861299.J421_3854	5.875e-156	503.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
GDHHQS2_k127_7205153_2	1403819.BATR01000016_gene478	8.072e-48	185.0	COG3685@1|root,COG3685@2|Bacteria,46VCV@74201|Verrucomicrobia,2IVZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
GDHHQS2_k127_7205153_4	111780.Sta7437_3182	9.259e-15	81.0	2E9TG@1|root,333ZH@2|Bacteria,1GKFI@1117|Cyanobacteria,3VN2S@52604|Pleurocapsales	1117|Cyanobacteria	S	Nuclease A inhibitor-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NuiA
GDHHQS2_k127_7205153_1	861299.J421_3849	8.904e-155	504.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_7205153_6	929556.Solca_4020	6.07e-05	53.0	2DKW8@1|root,30JES@2|Bacteria,4NPM5@976|Bacteroidetes,1ITXX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7205153_3	861299.J421_1574	7.223e-30	132.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS2_k127_7205153_5	379066.GAU_1030	1.574e-08	64.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS2_k127_7217724_4	861299.J421_2662	6.635e-80	268.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_7217724_3	861299.J421_2661	2.489e-84	285.0	COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS2_k127_7217724_0	861299.J421_2660	3.016e-299	933.0	COG0210@1|root,COG0210@2|Bacteria,1ZSMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS2_k127_7217724_2	861299.J421_2658	1.813e-117	389.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
GDHHQS2_k127_7217724_1	1042163.BRLA_c009020	7.643e-150	492.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS2_k127_7291291_1	1121918.ARWE01000001_gene3199	9.996e-58	209.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_7291291_2	1121918.ARWE01000001_gene3197	1.558e-30	130.0	COG2204@1|root,COG4567@1|root,COG2204@2|Bacteria,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
GDHHQS2_k127_7291291_0	1123508.JH636440_gene2646	4.131e-140	467.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_7291291_3	1408418.JNJH01000043_gene3127	2.121e-08	66.0	2FITE@1|root,34AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_732427_1	861299.J421_4036	3.019e-123	408.0	COG4774@1|root,COG4774@2|Bacteria,1ZTSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
GDHHQS2_k127_732427_0	861299.J421_3233	2.885e-125	413.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GDHHQS2_k127_732427_3	1032480.MLP_05660	9.934e-63	225.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria,4DP0G@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase,QueC
GDHHQS2_k127_732427_5	1167006.UWK_01647	2.287e-42	170.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,2MJ1E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GDHHQS2_k127_732427_2	379066.GAU_2868	1.391e-121	400.0	COG1600@1|root,COG1600@2|Bacteria,1ZU4X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
GDHHQS2_k127_732427_7	1379270.AUXF01000001_gene2453	2.271e-25	108.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_732427_4	861299.J421_3903	7.047e-57	202.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
GDHHQS2_k127_732427_6	582515.KR51_00001160	1.161e-26	117.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS2_k127_754860_4	1356852.N008_16385	2.362e-47	177.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,47N08@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_754860_3	1122605.KB893627_gene2919	6.082e-82	282.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,1IS5S@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS2_k127_754860_0	861299.J421_2891	8.533e-180	575.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS2_k127_754860_1	861299.J421_2892	2.047e-179	568.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS2_k127_754860_2	861299.J421_2895	9.414e-93	311.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GDHHQS2_k127_754860_5	379066.GAU_1135	7.172e-30	119.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS2_k127_76251_5	700598.Niako_0458	2.306e-68	243.0	COG0044@1|root,COG0044@2|Bacteria,4NJ1J@976|Bacteroidetes,1IVCT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0044 Dihydroorotase and related cyclic amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GDHHQS2_k127_76251_0	266117.Rxyl_0222	1.597e-193	616.0	COG1953@1|root,COG1953@2|Bacteria,2GJXN@201174|Actinobacteria	201174|Actinobacteria	FH	permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GDHHQS2_k127_76251_1	234267.Acid_7663	3.647e-147	469.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_76251_2	504728.K649_03245	3.915e-143	463.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS2_k127_76251_4	861299.J421_4223	7.95e-112	376.0	COG0531@1|root,COG0531@2|Bacteria,1ZSZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_76251_3	861299.J421_4481	6.45e-122	396.0	COG0501@1|root,COG0501@2|Bacteria,1ZSNK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS2_k127_84148_2	247490.KSU1_D0230	3.776e-33	132.0	COG2199@1|root,COG2203@1|root,COG3452@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria	2|Bacteria	T	CHASE	ytrP	-	2.7.7.65	ko:K02488,ko:K21009	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	CHASE,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS_3,PAS_8,Response_reg
GDHHQS2_k127_84148_1	351160.LRC161	6.075e-43	164.0	COG2032@1|root,arCOG05224@2157|Archaea,2Y3M1@28890|Euryarchaeota,2NAVG@224756|Methanomicrobia	224756|Methanomicrobia	P	Copper/zinc superoxide dismutase (SODC)	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
GDHHQS2_k127_84148_0	861299.J421_1711	2.395e-49	194.0	COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Caps_assemb_Wzi
GDHHQS2_k127_84148_3	204669.Acid345_1386	1.449e-24	106.0	2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_89085_1	379066.GAU_1256	1.308e-108	357.0	COG1199@1|root,COG1199@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
GDHHQS2_k127_89085_2	861299.J421_2983	1.837e-84	284.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_89085_0	861299.J421_3701	5.167e-170	547.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_89085_3	861299.J421_2984	9.115e-31	130.0	2FFNT@1|root,347K5@2|Bacteria,1ZTY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_916472_4	861299.J421_0328	1.804e-85	301.0	COG2041@1|root,COG2041@2|Bacteria,1ZUNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_916472_3	861299.J421_0327	4.824e-107	351.0	COG4117@1|root,COG4117@2|Bacteria,1ZUUH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GDHHQS2_k127_916472_1	861299.J421_3967	6.443e-135	438.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_916472_0	1379270.AUXF01000003_gene3404	1.025e-199	630.0	COG1206@1|root,COG1206@2|Bacteria,1ZTB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	gid	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS2_k127_916472_2	379066.GAU_2509	2.082e-114	370.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1ZTA9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS2_k127_937472_9	379066.GAU_1889	6.391e-28	116.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS2_k127_937472_7	1379270.AUXF01000006_gene70	1.892e-39	155.0	COG1579@1|root,COG1579@2|Bacteria,1ZU01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_937472_2	338963.Pcar_2679	6.3e-88	317.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS2_k127_937472_0	861299.J421_3463	3.49e-288	905.0	COG1193@1|root,COG1193@2|Bacteria,1ZSWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS2_k127_937472_5	861299.J421_3464	2.164e-56	199.0	COG1610@1|root,COG1610@2|Bacteria,1ZTS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS2_k127_937472_10	379066.GAU_1894	1.161e-27	112.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS2_k127_937472_6	861299.J421_3465	2.83e-40	153.0	COG0537@1|root,COG0537@2|Bacteria,1ZU0K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS2_k127_937472_4	861299.J421_3466	6.414e-76	263.0	COG1385@1|root,COG1385@2|Bacteria,1ZTJ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GDHHQS2_k127_937472_3	1379270.AUXF01000006_gene63	2.816e-82	286.0	COG2264@1|root,COG2264@2|Bacteria,1ZST2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS2_k127_937472_1	1379270.AUXF01000006_gene62	1.398e-167	533.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_937472_8	861299.J421_3469	2.137e-39	149.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GDHHQS2_k127_972314_0	861299.J421_2314	6.529e-134	436.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_972314_2	335543.Sfum_1623	3.93e-82	296.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS2_k127_972314_1	670292.JH26_11815	4.309e-121	399.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_972314_3	420324.KI911999_gene8063	2.882e-58	214.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_972314_5	861299.J421_4494	2.18e-27	115.0	COG3682@1|root,COG3682@2|Bacteria,1ZU4Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS2_k127_972314_4	509190.Cseg_0880	7.283e-35	140.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
GDHHQS2_k127_972314_6	448385.sce8846	1.427e-05	48.0	COG0640@1|root,COG0640@2|Bacteria,1RH4V@1224|Proteobacteria,43AH1@68525|delta/epsilon subdivisions,2X5X1@28221|Deltaproteobacteria,2Z038@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_986925_2	861299.J421_4230	4.305e-145	464.0	COG1048@1|root,COG1048@2|Bacteria,1ZTE7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS2_k127_986925_4	861299.J421_4232	1.754e-48	180.0	COG4420@1|root,COG4420@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS2_k127_986925_1	861299.J421_4235	2.632e-145	466.0	COG0388@1|root,COG0388@2|Bacteria,1ZTFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS2_k127_986925_0	861299.J421_4236	8.728e-158	513.0	COG2957@1|root,COG2957@2|Bacteria,1ZSZ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
GDHHQS2_k127_986925_3	861299.J421_4245	1.1e-56	202.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
GDHHQS2_k127_995482_0	1128421.JAGA01000003_gene3258	3.102e-183	594.0	COG2303@1|root,COG2303@2|Bacteria,2NRUE@2323|unclassified Bacteria	2|Bacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
GDHHQS2_k127_995482_3	861299.J421_3217	1.62e-35	143.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS2_k127_995482_1	1379270.AUXF01000004_gene3069	3.74e-165	537.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
GDHHQS2_k127_995482_2	379066.GAU_0826	1.656e-116	383.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
## 2303 queries scanned
## Total time (seconds): 13.007641792297363
## Rate: 177.05 q/s