## Fri Nov 15 22:51:53 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin3/GDHHQS_2_bin.70.fa -m mmseqs --itype genome -o GDHHQS_2_bin.70 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/GDHHQS_2_bin.70 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS2_k127_1124635_6	479434.Sthe_1611	1.474e-74	251.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS2_k127_1124635_27	1206739.BAGJ01000011_gene3375	3.989e-19	92.0	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria,4G243@85025|Nocardiaceae	201174|Actinobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
GDHHQS2_k127_1124635_3	760568.Desku_1293	1.461e-115	385.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,260IY@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS2_k127_1124635_17	1227352.C173_13122	1.984e-36	150.0	COG0627@1|root,COG0627@2|Bacteria,1V7KC@1239|Firmicutes,4HT81@91061|Bacilli,26V80@186822|Paenibacillaceae	91061|Bacilli	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS2_k127_1124635_5	926569.ANT_17290	3.809e-97	340.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS2_k127_1124635_2	485913.Krac_11884	6.288e-199	627.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GDHHQS2_k127_1124635_11	926569.ANT_31550	2.465e-45	170.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS2_k127_1124635_10	926569.ANT_08950	3.072e-47	196.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
GDHHQS2_k127_1124635_32	670487.Ocepr_1114	0.0009137	51.0	COG0797@1|root,COG1388@1|root,COG0797@2|Bacteria,COG1388@2|Bacteria,1WJRE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,LysM
GDHHQS2_k127_1124635_12	1128421.JAGA01000002_gene1343	5.978e-45	173.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
GDHHQS2_k127_1124635_9	105559.Nwat_2544	1.427e-53	196.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS2_k127_1124635_33	862751.SACTE_0784	0.0009559	51.0	2A964@1|root,30YAQ@2|Bacteria,2IBT5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
GDHHQS2_k127_1124635_19	479434.Sthe_2915	1.305e-35	142.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_1124635_22	383372.Rcas_1413	4.876e-26	117.0	COG1011@1|root,COG1011@2|Bacteria,2G9CU@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS2_k127_1124635_21	383372.Rcas_1413	2.129e-27	121.0	COG1011@1|root,COG1011@2|Bacteria,2G9CU@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS2_k127_1124635_25	591157.SSLG_02512	3.865e-22	106.0	COG4099@1|root,COG4099@2|Bacteria,2GSIX@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Peptidase_S9
GDHHQS2_k127_1124635_15	1128421.JAGA01000003_gene3355	1.434e-41	167.0	COG1466@1|root,COG1466@2|Bacteria,2NPN5@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III delta subunit	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
GDHHQS2_k127_1124635_8	1123508.JH636450_gene7226	3.612e-59	208.0	COG1607@1|root,COG1607@2|Bacteria,2J16W@203682|Planctomycetes	203682|Planctomycetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS2_k127_1124635_1	1173023.KE650771_gene1874	1.113e-220	717.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria,1JKMN@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS2_k127_1124635_29	1463885.KL578518_gene4924	1.686e-17	97.0	COG1524@1|root,COG1524@2|Bacteria,2HQI2@201174|Actinobacteria	201174|Actinobacteria	I	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_1124635_30	1246484.D479_17594	3.466e-14	85.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,3NEBV@45667|Halobacillus	91061|Bacilli	M	Ami_3	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
GDHHQS2_k127_1124635_14	398767.Glov_1588	1.354e-41	162.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS2_k127_1124635_23	1487921.DP68_00045	4.881e-25	108.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,24N37@186801|Clostridia,36JI0@31979|Clostridiaceae	186801|Clostridia	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GDHHQS2_k127_1124635_7	118166.JH976537_gene529	5.352e-66	229.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1H93G@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
GDHHQS2_k127_1124635_20	710686.Mycsm_03524	2.423e-29	129.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,235TR@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1124635_31	338969.Rfer_1230	4.24e-14	85.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,2VKH5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
GDHHQS2_k127_1124635_18	1382306.JNIM01000001_gene612	7.585e-36	138.0	COG0073@1|root,COG0073@2|Bacteria,2G74R@200795|Chloroflexi	200795|Chloroflexi	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
GDHHQS2_k127_1124635_16	926560.KE387023_gene2367	2.413e-40	159.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GDHHQS2_k127_1124635_4	926550.CLDAP_00060	1.648e-103	345.0	COG0265@1|root,COG0265@2|Bacteria,2G6I9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_1124635_24	36809.MAB_2860c	6.731e-25	111.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,238VI@1762|Mycobacteriaceae	201174|Actinobacteria	S	deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS2_k127_1124635_13	479434.Sthe_3216	1.446e-42	165.0	COG0265@1|root,COG0265@2|Bacteria,2G8UH@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_1124635_26	1385512.N784_10780	4.349e-21	95.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,2YB02@289201|Pontibacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
GDHHQS2_k127_1124635_28	926550.CLDAP_10530	4.43e-18	96.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_1124635_0	926550.CLDAP_38240	6.448e-282	872.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_113617_39	1382306.JNIM01000001_gene3705	1.426e-33	151.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2G8KB@200795|Chloroflexi	200795|Chloroflexi	K	NB-ARC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,NB-ARC,TPR_12
GDHHQS2_k127_113617_15	357808.RoseRS_2229	1.08e-81	297.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_113617_2	247490.KSU1_C0108	1.384e-174	559.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS2_k127_113617_50	585529.HMPREF0291_10413	9.725e-23	106.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,22JNZ@1653|Corynebacteriaceae	201174|Actinobacteria	E	phosphoserine phosphatase	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS2_k127_113617_46	1459636.NTE_00481	8.387e-26	121.0	arCOG03383@1|root,arCOG03383@2157|Archaea	2157|Archaea	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_113617_5	1123277.KB893172_gene626	1.444e-154	496.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,47NMZ@768503|Cytophagia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_113617_0	926550.CLDAP_11790	4.683e-270	882.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GDHHQS2_k127_113617_66	1034943.BN1094_01670	0.0002316	45.0	2APJP@1|root,31ENU@2|Bacteria,1QBZ6@1224|Proteobacteria,1T7KI@1236|Gammaproteobacteria,1JFHJ@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_18	926550.CLDAP_11780	6.935e-79	271.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_113617_26	926569.ANT_30110	1.732e-56	214.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS2_k127_113617_56	311424.DhcVS_1244	2.118e-10	67.0	2EHX5@1|root,33BNR@2|Bacteria,2GATV@200795|Chloroflexi,34DBX@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_3	111780.Sta7437_4188	2.557e-159	524.0	COG0642@1|root,COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,3VIPY@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
GDHHQS2_k127_113617_33	867845.KI911784_gene3533	2.567e-45	176.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39,2.5.1.42,2.5.1.74	ko:K02548,ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R04520,R05000,R05615,R05617,R06858,R10757	RC00209,RC01171,RC02895,RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
GDHHQS2_k127_113617_28	1185876.BN8_05038	2.12e-56	202.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,47RDY@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_113617_37	526227.Mesil_1246	4.065e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,1WN2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_113617_54	138119.DSY1933	8.104e-17	87.0	COG2206@1|root,COG2206@2|Bacteria,1VDUC@1239|Firmicutes,25DNP@186801|Clostridia,262JQ@186807|Peptococcaceae	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_113617_42	1132442.KB889752_gene3193	1.697e-31	131.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus	91061|Bacilli	S	Peptidase M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_113617_44	1122611.KB903962_gene4467	1.832e-26	123.0	COG1357@1|root,COG1409@1|root,COG2319@1|root,COG5635@1|root,COG1357@2|Bacteria,COG1409@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria,4EHU7@85012|Streptosporangiales	201174|Actinobacteria	T	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,TIR_2,Trypsin_2,WD40
GDHHQS2_k127_113617_22	1487953.JMKF01000058_gene5079	1.11e-67	236.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS2_k127_113617_51	497964.CfE428DRAFT_3955	5.493e-20	93.0	2EH6J@1|root,33AYF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_8	32057.KB217478_gene5481	5.374e-117	389.0	COG0477@1|root,COG2814@2|Bacteria,1G2WB@1117|Cyanobacteria	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
GDHHQS2_k127_113617_27	439235.Dalk_3111	2.025e-56	207.0	COG1073@1|root,COG1073@2|Bacteria,1RBV1@1224|Proteobacteria,42M9M@68525|delta/epsilon subdivisions,2WM64@28221|Deltaproteobacteria,2MJJ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS2_k127_113617_17	926560.KE387025_gene4131	1.765e-80	276.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_113617_64	1408422.JHYF01000008_gene3798	0.0001225	52.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,36IC8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_60	177437.HRM2_22560	1.003e-09	63.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,Trypsin_2
GDHHQS2_k127_113617_10	760192.Halhy_5052	5.135e-110	361.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1INMZ@117747|Sphingobacteriia	976|Bacteroidetes	P	ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GDHHQS2_k127_113617_4	926550.CLDAP_07090	4.58e-158	510.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS2_k127_113617_55	32057.KB217480_gene8334	3.268e-11	78.0	COG3591@1|root,COG4995@1|root,COG3591@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Trypsin_2,WD40
GDHHQS2_k127_113617_62	448385.sce0229	1.198e-07	62.0	COG1672@1|root,COG1672@2|Bacteria,1NTWM@1224|Proteobacteria,4381T@68525|delta/epsilon subdivisions,2X9V3@28221|Deltaproteobacteria,2YVBC@29|Myxococcales	28221|Deltaproteobacteria	O	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,TIR_2,Trypsin_2
GDHHQS2_k127_113617_30	742735.HMPREF9467_05103	5.139e-53	205.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_2,TPR_8
GDHHQS2_k127_113617_57	1150626.PHAMO_80072	5.691e-10	63.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales	204441|Rhodospirillales	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_7	1307761.L21SP2_1484	2.431e-117	395.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
GDHHQS2_k127_113617_11	1307761.L21SP2_1483	2.046e-100	334.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
GDHHQS2_k127_113617_21	1307761.L21SP2_1482	2.843e-68	243.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GDHHQS2_k127_113617_49	926550.CLDAP_10230	1.428e-23	116.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
GDHHQS2_k127_113617_67	35725.K2RBE2	0.00086	51.0	COG0823@1|root,2QPTW@2759|Eukaryota,38RVS@33154|Opisthokonta,3NZ8B@4751|Fungi,3QSE5@4890|Ascomycota,20410@147541|Dothideomycetes	4751|Fungi	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_113617_40	28564.XP_002488590.1	3.172e-33	149.0	KOG0266@1|root,KOG0271@1|root,KOG0266@2759|Eukaryota,KOG0271@2759|Eukaryota,38B6D@33154|Opisthokonta,3NZ4C@4751|Fungi	4751|Fungi	D	WD40 repeat-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,PNP_UDP_1,WD40
GDHHQS2_k127_113617_45	941639.BCO26_1784	2.241e-26	118.0	COG1814@1|root,COG1814@2|Bacteria,1V011@1239|Firmicutes,4I36W@91061|Bacilli,1ZE9R@1386|Bacillus	91061|Bacilli	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GDHHQS2_k127_113617_35	375286.mma_1696	5.588e-39	148.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,474RD@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
GDHHQS2_k127_113617_13	926550.CLDAP_09300	3.32e-85	293.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS2_k127_113617_20	1303518.CCALI_01253	4.891e-76	269.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
GDHHQS2_k127_113617_29	324602.Caur_2225	1.788e-54	215.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
GDHHQS2_k127_113617_25	649638.Trad_2741	4.219e-61	218.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
GDHHQS2_k127_113617_31	118163.Ple7327_3252	2.205e-49	179.0	COG1832@1|root,COG1832@2|Bacteria,1G704@1117|Cyanobacteria	1117|Cyanobacteria	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS2_k127_113617_41	926560.KE387023_gene1958	1.334e-31	132.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_23	439235.Dalk_4420	1.019e-66	243.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,42USJ@68525|delta/epsilon subdivisions,2WQ3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS2_k127_113617_65	1150864.MILUP08_43876	0.0001757	52.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_32	316274.Haur_1591	1.303e-46	174.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_113617_34	926569.ANT_31200	5.457e-44	184.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_113617_12	1173028.ANKO01000102_gene5411	8.595e-90	302.0	COG1656@1|root,COG1656@2|Bacteria,1G344@1117|Cyanobacteria,1HAHV@1150|Oscillatoriales	1117|Cyanobacteria	S	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
GDHHQS2_k127_113617_48	272134.KB731324_gene5406	1.256e-24	111.0	2C74Y@1|root,32QWW@2|Bacteria,1G6NB@1117|Cyanobacteria,1HDQE@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_113617_38	1123405.AUMM01000024_gene2062	7.443e-34	141.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,26NIW@186821|Sporolactobacillaceae	91061|Bacilli	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS2_k127_113617_53	1005048.CFU_1865	4.575e-19	98.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,474JN@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_113617_61	670487.Ocepr_0955	8.913e-09	62.0	COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
GDHHQS2_k127_113617_43	690585.JNNU01000002_gene4844	3.529e-31	134.0	COG2169@1|root,COG2169@2|Bacteria,1R5KX@1224|Proteobacteria,2U44Z@28211|Alphaproteobacteria,4B8NK@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
GDHHQS2_k127_113617_24	383372.Rcas_2471	2.357e-61	238.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_113617_6	316274.Haur_0133	4.055e-152	488.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_113617_9	926550.CLDAP_37650	4.588e-111	366.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS2_k127_113617_16	485913.Krac_0962	3.945e-81	293.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GDHHQS2_k127_113617_58	1408473.JHXO01000015_gene1906	7.706e-10	70.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GDHHQS2_k127_113617_1	316274.Haur_3070	1.534e-244	768.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_113617_59	244447.XP_008319167.1	9.606e-10	70.0	KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa,3CU75@33213|Bilateria,4841R@7711|Chordata,490A6@7742|Vertebrata,4A0W8@7898|Actinopterygii	33208|Metazoa	S	Chromosome 6 open reading frame 106	C6orf106	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,UBA_4
GDHHQS2_k127_113617_47	926569.ANT_31290	1.018e-25	121.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
GDHHQS2_k127_113617_14	926569.ANT_11270	7.797e-83	281.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
GDHHQS2_k127_113617_19	357808.RoseRS_3033	2.372e-76	271.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi,3771W@32061|Chloroflexia	32061|Chloroflexia	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GDHHQS2_k127_113617_36	868864.Dester_0517	5.608e-38	156.0	COG2801@1|root,COG2801@2|Bacteria,2G3YF@200783|Aquificae	200783|Aquificae	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,HTH_Tnp_Tc3_2,rve,rve_3
GDHHQS2_k127_1217171_38	616991.JPOO01000003_gene149	1.221e-45	168.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1I4BI@117743|Flavobacteriia,23IFP@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_1217171_43	760568.Desku_1970	1.92e-32	135.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_1217171_22	926550.CLDAP_25670	1.018e-76	264.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
GDHHQS2_k127_1217171_50	102129.Lepto7375DRAFT_6424	9.693e-18	87.0	COG4392@1|root,COG4392@2|Bacteria	2|Bacteria	E	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
GDHHQS2_k127_1217171_55	1173028.ANKO01000195_gene5937	7.879e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
GDHHQS2_k127_1217171_15	926569.ANT_28060	2.629e-89	301.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS2_k127_1217171_32	234267.Acid_0608	1.081e-58	225.0	COG1807@1|root,COG1807@2|Bacteria,3Y965@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_1217171_48	765420.OSCT_0452	1.259e-21	110.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
GDHHQS2_k127_1217171_46	1121377.KB906416_gene3978	2.842e-27	113.0	COG3339@1|root,COG3339@2|Bacteria,1WN6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS2_k127_1217171_40	759914.BP951000_1076	1.478e-36	151.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_1217171_3	926569.ANT_31260	2.635e-192	611.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS2_k127_1217171_51	1120934.KB894403_gene289	1.045e-17	95.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,2I3FC@201174|Actinobacteria,4EFCV@85010|Pseudonocardiales	201174|Actinobacteria	Q	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_1217171_35	1174528.JH992898_gene2677	3.676e-54	202.0	COG3173@1|root,COG3173@2|Bacteria,1GKJB@1117|Cyanobacteria,1JMB4@1189|Stigonemataceae	1117|Cyanobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS2_k127_1217171_23	1382304.JNIL01000001_gene1526	2.809e-76	265.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli	91061|Bacilli	S	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
GDHHQS2_k127_1217171_7	926569.ANT_23360	1.496e-124	413.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1217171_54	1347392.CCEZ01000044_gene630	1.341e-15	83.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,36HYR@31979|Clostridiaceae	186801|Clostridia	K	PFAM Transcription factor CarD	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
GDHHQS2_k127_1217171_30	926549.KI421517_gene1458	5.433e-65	234.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_1217171_33	485913.Krac_4538	1.119e-57	213.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
GDHHQS2_k127_1217171_25	926569.ANT_06070	1.747e-68	246.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS2_k127_1217171_36	926569.ANT_20320	6.589e-54	201.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GDHHQS2_k127_1217171_16	383372.Rcas_1949	2.379e-86	294.0	COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi,374YQ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
GDHHQS2_k127_1217171_10	56107.Cylst_1884	6.189e-111	372.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
GDHHQS2_k127_1217171_5	1128421.JAGA01000003_gene3664	4.17e-166	544.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
GDHHQS2_k127_1217171_9	1128421.JAGA01000003_gene3665	9.293e-112	368.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
GDHHQS2_k127_1217171_59	953739.SVEN_0036	4.62e-08	64.0	2ECD7@1|root,336BF@2|Bacteria,2IH9P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1217171_28	926561.KB900621_gene2735	4.025e-66	233.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WAMX@53433|Halanaerobiales	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GDHHQS2_k127_1217171_34	395493.BegalDRAFT_2144	6.478e-56	220.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_1217171_42	521011.Mpal_2259	2.603e-34	152.0	COG0642@1|root,arCOG02327@2157|Archaea,2XT8K@28890|Euryarchaeota,2NACV@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS
GDHHQS2_k127_1217171_52	63737.Npun_R4703	1.73e-17	87.0	COG1487@1|root,COG1487@2|Bacteria,1G7BZ@1117|Cyanobacteria,1HNQB@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_1217171_8	926569.ANT_09810	1.533e-123	405.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS2_k127_1217171_6	1128421.JAGA01000003_gene3727	7.737e-145	465.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS2_k127_1217171_26	383372.Rcas_1156	2.162e-68	252.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS2_k127_1217171_0	1382306.JNIM01000001_gene2493	0.0	1093.0	COG1012@1|root,COG1012@2|Bacteria,2G86D@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_1217171_49	290397.Adeh_3229	1.315e-20	106.0	COG0675@1|root,COG0675@2|Bacteria,1NIWW@1224|Proteobacteria	1224|Proteobacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1217171_56	1392498.JQLH01000001_gene3336	2.156e-12	72.0	2EQK1@1|root,33I62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1217171_18	1192034.CAP_2251	1.017e-84	288.0	COG2267@1|root,COG2267@2|Bacteria,1PDD2@1224|Proteobacteria,430GU@68525|delta/epsilon subdivisions,2WW4T@28221|Deltaproteobacteria,2YYCY@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_1217171_29	555779.Dthio_PD2854	1.272e-65	236.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2M9KN@213115|Desulfovibrionales	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS2_k127_1217171_37	1291050.JAGE01000001_gene1388	3.228e-53	200.0	COG0614@1|root,COG0614@2|Bacteria,1V1QH@1239|Firmicutes,24M5R@186801|Clostridia	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS2_k127_1217171_20	1501230.ET33_03115	6.313e-82	284.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,26TBZ@186822|Paenibacillaceae	91061|Bacilli	P	ABC 3 transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS2_k127_1217171_57	926550.CLDAP_01430	6.369e-10	67.0	COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi	2|Bacteria	C	Cytochrome c	soxX	-	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cytochrom_C
GDHHQS2_k127_1217171_21	926550.CLDAP_29300	9.123e-81	279.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_1217171_44	366394.Smed_5352	3.659e-29	131.0	COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria,4B79H@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS2_k127_1217171_2	926569.ANT_09360	2.087e-192	608.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS2_k127_1217171_13	926569.ANT_15400	4.852e-97	326.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1217171_12	1121377.KB906409_gene895	6.565e-109	368.0	COG2124@1|root,COG2124@2|Bacteria,1WIX6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS2_k127_1217171_45	1118054.CAGW01000053_gene1474	8.811e-29	122.0	COG1309@1|root,COG1309@2|Bacteria,1VCXD@1239|Firmicutes,4HM5E@91061|Bacilli,275FF@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_1217171_39	118173.KB235914_gene3326	7.859e-37	151.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_1217171_41	479434.Sthe_2734	8.474e-35	140.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
GDHHQS2_k127_1217171_17	2002.JOEQ01000029_gene8183	1.026e-85	299.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4ENK8@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_1217171_31	1469607.KK073768_gene2235	5.546e-63	229.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HRAP@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_1217171_11	926569.ANT_24700	6.319e-111	369.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS2_k127_1217171_53	886379.AEWI01000013_gene2172	4.31e-17	91.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia,3XJ4U@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_1217171_61	913325.N799_08795	1.94e-05	56.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales	135614|Xanthomonadales	M	Lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
GDHHQS2_k127_1217171_4	671143.DAMO_0407	3.36e-168	550.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_1217171_47	1499967.BAYZ01000036_gene2414	1.604e-24	108.0	2BK9M@1|root,32EPT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1217171_27	357808.RoseRS_2229	3.409e-66	250.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_1217171_1	1128421.JAGA01000003_gene3696	3.141e-208	663.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS2_k127_1217171_58	1121272.KB903291_gene3329	3.617e-09	63.0	2BKAB@1|root,32EQK@2|Bacteria,2GXJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1217171_14	1408254.T458_09100	3.618e-96	325.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS2_k127_1217171_24	386456.JQKN01000017_gene840	4.541e-75	258.0	COG4912@1|root,arCOG11010@2157|Archaea,2XWKG@28890|Euryarchaeota,23PIX@183925|Methanobacteria	183925|Methanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_1217171_19	1123226.KB899285_gene3854	5.449e-82	280.0	COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,4HD38@91061|Bacilli,26RAT@186822|Paenibacillaceae	91061|Bacilli	S	Predicted nucleotidyltransferase	ycgL	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
GDHHQS2_k127_1239282_2	1183438.GKIL_3375	5.888e-57	211.0	COG0596@1|root,COG0596@2|Bacteria,1G05K@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1239282_3	926549.KI421517_gene2169	7.729e-33	134.0	COG0824@1|root,COG0824@2|Bacteria,4NK6Y@976|Bacteroidetes,47N55@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2,Acyl-ACP_TE
GDHHQS2_k127_1239282_1	211165.AJLN01000104_gene6520	6.608e-66	230.0	COG1309@1|root,COG1309@2|Bacteria,1G5HM@1117|Cyanobacteria,1JI00@1189|Stigonemataceae	1117|Cyanobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_C_13,TetR_C_6,TetR_N
GDHHQS2_k127_1239282_0	1499967.BAYZ01000181_gene4493	1.304e-192	614.0	COG0337@1|root,COG0337@2|Bacteria,2NP5Z@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4	ko:K01735,ko:K13829,ko:K19969,ko:K21342	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R02412,R03083,R10937	RC00002,RC00078,RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS2_k127_1239282_4	688269.Theth_1389	2.368e-11	72.0	COG1609@1|root,COG1609@2|Bacteria,2GC47@200918|Thermotogae	200918|Thermotogae	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1
GDHHQS2_k127_1380844_5	713586.KB900536_gene328	2.775e-43	163.0	COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria	1224|Proteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
GDHHQS2_k127_1380844_9	1385935.N836_17730	1.691e-18	91.0	COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1H7FH@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	ycf29	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_1380844_0	1382356.JQMP01000003_gene2608	5.163e-159	511.0	COG0579@1|root,COG0579@2|Bacteria,2G67E@200795|Chloroflexi,27XHD@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD dependent oxidoreductase	-	-	1.1.99.2	ko:K00109	ko00650,map00650	-	R03534	RC00031	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS2_k127_1380844_11	66897.DJ64_07180	1.485e-10	73.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3,Pkinase
GDHHQS2_k127_1380844_2	926569.ANT_31030	2.275e-93	318.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS2_k127_1380844_4	935948.KE386494_gene260	4.928e-65	228.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS2_k127_1380844_1	926550.CLDAP_41120	3.25e-103	341.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_1380844_7	661478.OP10G_0619	9.743e-43	175.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
GDHHQS2_k127_1380844_3	861299.J421_6076	1.049e-80	278.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
GDHHQS2_k127_1380844_6	35754.JNYJ01000043_gene4416	5.75e-43	166.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4DK0U@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1380844_8	1121015.N789_00635	3.757e-25	113.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,1SGRZ@1236|Gammaproteobacteria,1X6RX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS2_k127_1380844_10	886293.Sinac_7127	7.357e-11	74.0	COG0823@1|root,COG0823@2|Bacteria,2IZKS@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_1479758_5	1128421.JAGA01000002_gene1395	1.03e-09	61.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1479758_4	670487.Ocepr_2155	3.329e-42	156.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_1479758_1	316274.Haur_0901	9.561e-75	258.0	COG1011@1|root,COG1011@2|Bacteria,2G916@200795|Chloroflexi,377HS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS2_k127_1479758_3	316274.Haur_0169	3.205e-52	187.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	yffH	-	-	-	-	-	-	-	-	-	-	-	DUF4406
GDHHQS2_k127_1479758_6	43354.JOIJ01000007_gene1554	3.495e-06	59.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	psrP1	-	-	ko:K12548,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_5,CHU_C,DUF11,SWM_repeat,SdrD_B,SprB
GDHHQS2_k127_1479758_2	471853.Bcav_1567	2.324e-52	195.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_1479758_0	485913.Krac_3074	1.158e-138	451.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS2_k127_1511903_70	1444309.JAQG01000013_gene1917	1.076e-08	67.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HUAQ@91061|Bacilli,2765A@186822|Paenibacillaceae	91061|Bacilli	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_1511903_24	1227487.C474_13819	2.471e-96	320.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,23S6X@183963|Halobacteria	183963|Halobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
GDHHQS2_k127_1511903_48	867903.ThesuDRAFT_01405	1.589e-31	128.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
GDHHQS2_k127_1511903_52	653733.Selin_0567	1.549e-24	110.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
GDHHQS2_k127_1511903_15	653733.Selin_0567	5.996e-121	403.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
GDHHQS2_k127_1511903_67	589924.Ferp_0125	1.499e-11	76.0	COG1622@1|root,arCOG01236@2157|Archaea	2157|Archaea	C	Heme copper-type cytochrome quinol oxidases, subunit 2	soxA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1	ko:K02275,ko:K02826,ko:K15864	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00416,M00529	R00081,R00143,R00783,R00785,R09492	RC00016,RC00086,RC00819,RC02797	ko00000,ko00001,ko00002,ko01000	3.D.4.1,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Cytochrom_D1,TAT_signal
GDHHQS2_k127_1511903_72	530564.Psta_3515	2.552e-07	62.0	COG2010@1|root,COG2010@2|Bacteria,2IZN4@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,EB_dh
GDHHQS2_k127_1511903_37	926569.ANT_26550	2.214e-53	199.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
GDHHQS2_k127_1511903_79	309800.C498_16513	0.0002646	46.0	COG0526@1|root,arCOG01972@2157|Archaea,2XZ0C@28890|Euryarchaeota,23WWM@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	trxA1	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS2_k127_1511903_43	926550.CLDAP_14450	6.265e-39	154.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS2_k127_1511903_21	644966.Tmar_0771	9.181e-102	341.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1511903_9	644966.Tmar_0772	1.601e-130	433.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_1511903_74	335541.Swol_1698	5.703e-06	54.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42JMM@68298|Syntrophomonadaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_1511903_51	760568.Desku_3266	8.81e-25	111.0	COG0500@1|root,COG2226@2|Bacteria,1V6G6@1239|Firmicutes,24H8Z@186801|Clostridia,26359@186807|Peptococcaceae	186801|Clostridia	H	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_1511903_55	1382306.JNIM01000001_gene2831	2.181e-22	101.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_6	926560.KE387027_gene437	1.71e-145	475.0	COG1541@1|root,COG1541@2|Bacteria,1WM4P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_68	641491.DND132_2968	5.378e-11	67.0	COG3462@1|root,COG3462@2|Bacteria,1QE33@1224|Proteobacteria,43EKD@68525|delta/epsilon subdivisions,2X0Z4@28221|Deltaproteobacteria,2MDTR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GDHHQS2_k127_1511903_54	1120973.AQXL01000059_gene3202	1.036e-22	102.0	COG0785@1|root,COG0785@2|Bacteria,1UN00@1239|Firmicutes,4HBBT@91061|Bacilli	91061|Bacilli	O	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
GDHHQS2_k127_1511903_59	1476583.DEIPH_ctg139orf0011	2.314e-18	90.0	COG0785@1|root,COG0785@2|Bacteria,1WJ8B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
GDHHQS2_k127_1511903_14	1121377.KB906409_gene857	5.167e-122	421.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
GDHHQS2_k127_1511903_42	533247.CRD_02146	1.678e-39	158.0	COG4221@1|root,COG4221@2|Bacteria,1G156@1117|Cyanobacteria,1HKAR@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_1511903_47	926550.CLDAP_16180	1.463e-31	128.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
GDHHQS2_k127_1511903_29	1499967.BAYZ01000038_gene2261	5.082e-83	282.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_1511903_58	926569.ANT_28110	1.188e-18	88.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS2_k127_1511903_64	1536774.H70357_02525	1.284e-13	74.0	COG3237@1|root,COG3237@2|Bacteria,1VFTC@1239|Firmicutes,4HNXJ@91061|Bacilli,26Z7A@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_1511903_49	243230.DR_1710	1.287e-29	119.0	arCOG05253@1|root,31CTK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
GDHHQS2_k127_1511903_63	1461694.ATO9_10605	6.33e-16	81.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,2PEPV@252301|Oceanicola	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_1511903_56	251229.Chro_0991	2.9e-21	99.0	COG0762@1|root,COG0762@2|Bacteria,1G9UC@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
GDHHQS2_k127_1511903_62	1123009.AUID01000008_gene835	2.013e-16	83.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_1511903_76	1230343.CANP01000041_gene3070	2.387e-05	48.0	2APJP@1|root,31ENU@2|Bacteria,1QBZ6@1224|Proteobacteria,1T7KI@1236|Gammaproteobacteria,1JFHJ@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_77	1123376.AUIU01000015_gene366	8.506e-05	49.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS2_k127_1511903_53	1121271.AUCM01000014_gene2737	1.591e-24	109.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1511903_46	317936.Nos7107_3521	6.016e-34	134.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_75	1127134.NOCYR_2748	1.841e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2IG3F@201174|Actinobacteria,4G5S0@85025|Nocardiaceae	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
GDHHQS2_k127_1511903_78	398511.BpOF4_02310	0.0001028	47.0	2EFZF@1|root,339RM@2|Bacteria,1VMG6@1239|Firmicutes,4HR8G@91061|Bacilli,1ZK3J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_2	1242864.D187_001830	1.626e-188	621.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_1511903_33	326427.Cagg_2708	1.742e-70	256.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_1511903_30	926569.ANT_20410	1.288e-74	256.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1511903_27	1120973.AQXL01000125_gene3124	2.024e-84	294.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,2795F@186823|Alicyclobacillaceae	91061|Bacilli	V	MacB-like periplasmic core domain	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1511903_26	1392488.JHZY01000004_gene3559	1.377e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,2XI6V@283735|Leeuwenhoekiella	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_1511903_50	748727.CLJU_c23270	5.81e-27	125.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,36GVR@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS2_k127_1511903_44	284031.JNXD01000006_gene2831	5.731e-37	150.0	COG3620@1|root,COG3837@1|root,COG3620@2|Bacteria,COG3837@2|Bacteria,2I4X7@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
GDHHQS2_k127_1511903_25	485913.Krac_9361	1.985e-87	298.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS2_k127_1511903_5	1382306.JNIM01000001_gene2429	2.559e-147	472.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
GDHHQS2_k127_1511903_4	1382306.JNIM01000001_gene2428	1.166e-155	496.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_1511903_0	485913.Krac_9358	1.559e-223	700.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_1511903_7	485913.Krac_9357	3.204e-131	431.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_1511903_34	463191.SSEG_09289	1.146e-63	228.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_1511903_19	1463917.JODC01000007_gene7463	1.112e-105	350.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_1511903_31	66874.JOFS01000008_gene2289	4.397e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS2_k127_1511903_12	266117.Rxyl_0206	2.064e-127	421.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1511903_32	1122214.AQWH01000008_gene1568	7.45e-72	255.0	COG1172@1|root,COG1172@2|Bacteria,1MX1K@1224|Proteobacteria,2TUYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GDHHQS2_k127_1511903_18	1122214.AQWH01000008_gene1566	2.798e-107	361.0	COG1879@1|root,COG1879@2|Bacteria,1N1FF@1224|Proteobacteria,2UDI7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GDHHQS2_k127_1511903_13	1122214.AQWH01000008_gene1567	3.14e-122	409.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,2PK99@255475|Aurantimonadaceae	28211|Alphaproteobacteria	G	import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
GDHHQS2_k127_1511903_35	314256.OG2516_16029	1.206e-59	234.0	COG1129@1|root,COG1129@2|Bacteria,1PF40@1224|Proteobacteria,2V7FI@28211|Alphaproteobacteria,2PF7J@252301|Oceanicola	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
GDHHQS2_k127_1511903_10	1087481.AGFX01000018_gene1781	3.904e-129	444.0	COG0402@1|root,COG0402@2|Bacteria,1VTFK@1239|Firmicutes,4HTWB@91061|Bacilli,26V47@186822|Paenibacillaceae	91061|Bacilli	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_1511903_11	926569.ANT_08450	8.5e-128	420.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_1511903_45	644282.Deba_2768	4.789e-36	148.0	COG0223@1|root,COG0223@2|Bacteria,1N4Z4@1224|Proteobacteria,42UF3@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
GDHHQS2_k127_1511903_28	1128421.JAGA01000004_gene2684	2.405e-84	283.0	COG2148@1|root,COG2148@2|Bacteria,2NPJQ@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	epsL	-	-	ko:K19428	-	-	-	-	ko00000,ko01000	-	-	-	Bac_transf
GDHHQS2_k127_1511903_20	983545.Glaag_0284	3.703e-105	353.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1511903_8	211165.AJLN01000094_gene1165	8.656e-131	429.0	COG0438@1|root,COG0438@2|Bacteria,1G4VA@1117|Cyanobacteria,1JJSD@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GDHHQS2_k127_1511903_22	373994.Riv7116_2167	4.971e-100	342.0	2E6ZM@1|root,331IQ@2|Bacteria,1GDKK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1511903_16	1173023.KE650771_gene3071	2.366e-119	395.0	COG0438@1|root,COG0438@2|Bacteria,1GJ33@1117|Cyanobacteria,1JKHQ@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
GDHHQS2_k127_1511903_41	1292035.H476_0601	6.018e-41	156.0	COG0110@1|root,COG0110@2|Bacteria,1VHW4@1239|Firmicutes,24SX9@186801|Clostridia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep_2
GDHHQS2_k127_1511903_23	251229.Chro_1207	5.176e-99	338.0	COG2244@1|root,COG2244@2|Bacteria,1G07A@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
GDHHQS2_k127_1511903_1	1123386.AUIW01000007_gene1593	3.86e-200	641.0	COG1086@1|root,COG1086@2|Bacteria,1WIQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
GDHHQS2_k127_1511903_17	861299.J421_4222	3.59e-119	395.0	COG3844@1|root,COG3844@2|Bacteria,1ZTZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_1511903_39	477184.KYC_16177	1.074e-44	170.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,3T3Q7@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS2_k127_1511903_36	886293.Sinac_5694	9.709e-54	216.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_1511903_71	926550.CLDAP_11920	8.204e-08	66.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
GDHHQS2_k127_1511903_61	263358.VAB18032_02490	3.969e-17	86.0	COG0748@1|root,COG0748@2|Bacteria,2I5PB@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_1511903_57	926550.CLDAP_18910	4.605e-19	97.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,Glyco_hydro_19,LysM,PG_binding_1,Peptidase_C39_2,SLT
GDHHQS2_k127_1511903_66	521011.Mpal_1930	2.391e-12	71.0	COG1366@1|root,arCOG06891@2157|Archaea	2157|Archaea	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
GDHHQS2_k127_1511903_60	1217714.F975_00520	4.605e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,3NIRG@468|Moraxellaceae	1236|Gammaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1511903_40	644966.Tmar_0257	4.025e-43	162.0	COG1622@1|root,COG1622@2|Bacteria,1TPMD@1239|Firmicutes	1239|Firmicutes	C	COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2	cbaB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GDHHQS2_k127_1511903_38	1229780.BN381_450058	1.544e-46	180.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,3UWHG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS2_k127_1511903_3	324602.Caur_2426	1.356e-175	572.0	COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi,37691@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_1575186_6	525904.Tter_0641	1.038e-54	200.0	COG2197@1|root,COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2NR2Y@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	ydfH	-	2.7.13.3	ko:K02479,ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GerE,HATPase_c,HisKA,HisKA_3,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_1575186_4	357808.RoseRS_3190	1.135e-95	324.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_1575186_0	926569.ANT_28950	4.915e-164	533.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
GDHHQS2_k127_1575186_7	485913.Krac_0922	1.591e-44	164.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_1575186_8	1237149.C900_04367	3.558e-24	115.0	2D1WT@1|root,32TBK@2|Bacteria,4NU82@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1575186_1	926569.ANT_00900	3.436e-162	521.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GDHHQS2_k127_1575186_5	1201288.M900_1005	4.995e-79	287.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,42Y3Q@68525|delta/epsilon subdivisions,2MTU8@213481|Bdellovibrionales,2WT53@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
GDHHQS2_k127_1575186_2	765869.BDW_12965	5.933e-126	410.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2MUQT@213481|Bdellovibrionales,2WPP7@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_1575186_9	448385.sce1012	1.667e-19	99.0	COG2021@1|root,COG2021@2|Bacteria,1PG00@1224|Proteobacteria,439DK@68525|delta/epsilon subdivisions,2X4NG@28221|Deltaproteobacteria,2YZAN@29|Myxococcales	28221|Deltaproteobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1575186_3	383372.Rcas_2537	8.471e-97	340.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_1689356_19	383372.Rcas_3381	5.023e-67	252.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_1689356_35	485913.Krac_12581	5.142e-33	139.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_1689356_11	479434.Sthe_3402	3.953e-88	305.0	COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_1689356_24	324602.Caur_2958	1.575e-60	220.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_1689356_18	357808.RoseRS_2229	2.153e-70	259.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_1689356_46	889378.Spiaf_1100	8.827e-15	83.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
GDHHQS2_k127_1689356_47	195253.Syn6312_2604	2.376e-14	82.0	COG1357@1|root,COG1357@2|Bacteria,1G1UU@1117|Cyanobacteria,1H17N@1129|Synechococcus	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_1689356_21	1230476.C207_01739	1.714e-64	235.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,3JW0V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
GDHHQS2_k127_1689356_41	266117.Rxyl_2945	1.344e-18	89.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_1689356_2	1195236.CTER_0541	1.241e-236	758.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS2_k127_1689356_26	1382356.JQMP01000003_gene1359	1.222e-59	222.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS2_k127_1689356_49	483215.BACFIN_04963	7.786e-11	71.0	COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia,4ARR3@815|Bacteroidaceae	976|Bacteroidetes	KT	PspC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PspC
GDHHQS2_k127_1689356_43	435591.BDI_0281	7.507e-16	81.0	COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PspC
GDHHQS2_k127_1689356_51	243233.MCA1431	6.054e-09	61.0	COG1366@1|root,COG1366@2|Bacteria,1NFGI@1224|Proteobacteria,1SEE0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_1689356_53	42256.RradSPS_1626	0.0002214	49.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_1689356_45	66869.JNXG01000004_gene2576	7.432e-15	77.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,41BBM@629295|Streptomyces griseus group	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
GDHHQS2_k127_1689356_36	1078085.HMPREF1210_03334	2.556e-31	126.0	COG0346@1|root,COG0346@2|Bacteria,1VCGT@1239|Firmicutes,4HKDV@91061|Bacilli,26FTE@186818|Planococcaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_1689356_8	926550.CLDAP_08640	2.859e-111	370.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
GDHHQS2_k127_1689356_14	192952.MM_2426	5.054e-76	264.0	COG0412@1|root,arCOG01659@2157|Archaea,2XZUN@28890|Euryarchaeota	28890|Euryarchaeota	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH,Peptidase_S9
GDHHQS2_k127_1689356_10	1382306.JNIM01000001_gene2454	2.884e-99	331.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS2_k127_1689356_15	479434.Sthe_2777	6.384e-74	252.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
GDHHQS2_k127_1689356_0	518766.Rmar_2766	0.0	1205.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_1689356_13	485913.Krac_6952	1.026e-79	278.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi	200795|Chloroflexi	O	YHS domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
GDHHQS2_k127_1689356_20	383372.Rcas_0660	2.722e-66	238.0	COG0303@1|root,COG0303@2|Bacteria,2G99Q@200795|Chloroflexi,3772N@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
GDHHQS2_k127_1689356_44	1295642.H839_07809	4.764e-15	81.0	COG3427@1|root,COG3427@2|Bacteria,1V6I3@1239|Firmicutes,4HJJD@91061|Bacilli	91061|Bacilli	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GDHHQS2_k127_1689356_9	1366046.HIMB11_01378	8.15e-100	334.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,3ZI16@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	AAA domain (dynein-related subfamily)	MA20_09400	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GDHHQS2_k127_1689356_7	357808.RoseRS_2165	2.628e-115	384.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia	32061|Chloroflexia	S	SMART von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
GDHHQS2_k127_1689356_16	571166.KI421509_gene1124	2.132e-72	257.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	MA20_09415	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS2_k127_1689356_22	926550.CLDAP_19040	3.847e-64	229.0	COG1414@1|root,COG1414@2|Bacteria,2G71X@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GDHHQS2_k127_1689356_38	228410.NE0622	5.895e-24	104.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_1689356_5	1123073.KB899241_gene2287	7.902e-151	486.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_1689356_39	1382359.JIAL01000001_gene418	8.328e-24	106.0	COG0454@1|root,COG0456@2|Bacteria,3Y5G1@57723|Acidobacteria,2JJWU@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_1689356_3	1123073.KB899241_gene2286	2.215e-225	711.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,1X5MS@135614|Xanthomonadales	135614|Xanthomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_1689356_17	1501230.ET33_18485	5.519e-71	260.0	COG0531@1|root,COG0531@2|Bacteria,1UZ53@1239|Firmicutes,4HEZV@91061|Bacilli,274S1@186822|Paenibacillaceae	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
GDHHQS2_k127_1689356_6	204669.Acid345_1270	1.743e-119	402.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GDHHQS2_k127_1689356_23	469382.Hbor_09240	6.207e-64	233.0	COG3608@1|root,arCOG02890@2157|Archaea,2XUVB@28890|Euryarchaeota,23UWM@183963|Halobacteria	183963|Halobacteria	S	Deacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
GDHHQS2_k127_1689356_4	926550.CLDAP_18710	1.552e-175	558.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.12.19,1.14.15.7	ko:K00479,ko:K00499,ko:K05708	ko00260,ko00360,ko01120,ko01220,map00260,map00360,map01120,map01220	M00545	R06782,R06783,R07409	RC00087,RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS2_k127_1689356_40	402777.KB235904_gene4700	4.871e-21	99.0	COG2319@1|root,COG2319@2|Bacteria,1G6MB@1117|Cyanobacteria,1HFUY@1150|Oscillatoriales	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GDHHQS2_k127_1689356_37	247156.NFA_28900	4.171e-27	119.0	COG1670@1|root,COG1670@2|Bacteria,2IT84@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_1689356_1	926569.ANT_14760	2.881e-262	821.0	COG1506@1|root,COG1506@2|Bacteria,2G5Z2@200795|Chloroflexi	200795|Chloroflexi	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_1689356_32	314285.KT71_13220	1.053e-34	142.0	COG1073@1|root,COG1073@2|Bacteria,1RC0W@1224|Proteobacteria,1SEQJ@1236|Gammaproteobacteria,1J96E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS2_k127_1689356_25	316274.Haur_0796	9.182e-60	224.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,375GE@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_1689356_31	1125863.JAFN01000001_gene2210	2.138e-40	154.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS2_k127_1689356_12	525897.Dbac_0438	4.799e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,1REB0@1224|Proteobacteria,42W2N@68525|delta/epsilon subdivisions,2WRYM@28221|Deltaproteobacteria,2MC8S@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_1689356_33	1121104.AQXH01000001_gene855	1.916e-33	149.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1IVMQ@117747|Sphingobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_1689356_50	1461582.BN1048_00946	1.019e-09	67.0	COG0398@1|root,COG0398@2|Bacteria,1VJCM@1239|Firmicutes,4HR9J@91061|Bacilli,4H0EJ@90964|Staphylococcaceae	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_1689356_27	479434.Sthe_3033	1.482e-56	202.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS2_k127_1689356_30	1148.1652134	1.324e-44	164.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1H5P0@1142|Synechocystis	1117|Cyanobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	ytfC	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
GDHHQS2_k127_1689356_52	1463926.JOCA01000040_gene2021	2.762e-08	64.0	COG0654@1|root,COG1716@1|root,COG0654@2|Bacteria,COG1716@2|Bacteria,2I9P3@201174|Actinobacteria	201174|Actinobacteria	CHT	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_1689356_28	1128427.KB904821_gene1147	1.035e-55	201.0	COG5018@1|root,COG5018@2|Bacteria,1G654@1117|Cyanobacteria,1HB8A@1150|Oscillatoriales	1117|Cyanobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
GDHHQS2_k127_1689356_34	1192034.CAP_8803	3.262e-33	138.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2Z0HP@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
GDHHQS2_k127_1762878_28	1220534.B655_1704	5.062e-53	190.0	COG0784@1|root,arCOG02589@2157|Archaea,2XVUK@28890|Euryarchaeota	28890|Euryarchaeota	T	response regulator, receiver	rre-1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GDHHQS2_k127_1762878_20	1123508.JH636449_gene7420	3.113e-85	306.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_1762878_62	1121377.KB906403_gene3055	3.982e-10	71.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH,Hydrolase_4
GDHHQS2_k127_1762878_4	765420.OSCT_2101	1.662e-208	665.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS2_k127_1762878_48	1177154.Y5S_00370	1.267e-24	108.0	COG1017@1|root,COG1017@2|Bacteria,1QUQ4@1224|Proteobacteria,1SAA1@1236|Gammaproteobacteria,1XQ83@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	Globin
GDHHQS2_k127_1762878_57	519989.ECTPHS_00550	3.2e-16	83.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_1762878_49	269799.Gmet_2789	6.017e-24	107.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,42T3B@68525|delta/epsilon subdivisions,2WP8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_1762878_26	760117.JN27_14595	2.401e-58	226.0	COG0745@1|root,COG0784@1|root,COG4251@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4729C@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
GDHHQS2_k127_1762878_31	316274.Haur_2932	1.055e-50	193.0	COG0715@1|root,COG0715@2|Bacteria,2GAAN@200795|Chloroflexi,377FK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_1762878_53	748658.KB907312_gene1825	7.26e-20	96.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RZDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_1762878_68	221360.RS9917_05165	0.0001162	50.0	COG0745@1|root,COG0745@2|Bacteria,1GCJD@1117|Cyanobacteria,1GZ11@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1762878_33	224324.aq_1554	9.15e-47	181.0	COG1830@1|root,COG1830@2|Bacteria,2G3TY@200783|Aquificae	200783|Aquificae	G	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GDHHQS2_k127_1762878_30	498761.HM1_2078	9.276e-51	188.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia	186801|Clostridia	K	response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1762878_41	383372.Rcas_3826	4.561e-37	164.0	COG4191@1|root,COG4191@2|Bacteria,2GBJB@200795|Chloroflexi,375H4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_1762878_32	1173027.Mic7113_2435	6.46e-49	203.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS2_k127_1762878_34	926569.ANT_15980	2.987e-42	171.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1762878_21	926569.ANT_19710	8.793e-77	265.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS2_k127_1762878_39	926569.ANT_19700	1.832e-39	154.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_1762878_37	796606.BMMGA3_13040	5.212e-40	171.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
GDHHQS2_k127_1762878_38	292459.STH732	1.733e-39	166.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS2_k127_1762878_70	1137281.D778_00500	0.0002859	50.0	2C59T@1|root,305DH@2|Bacteria,4NNXD@976|Bacteroidetes,1I259@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1762878_18	383372.Rcas_2957	9.45e-89	306.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi,374XV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_1762878_63	1550073.JROH01000012_gene2522	1.183e-08	61.0	2AAS0@1|root,3104G@2|Bacteria,1PN4I@1224|Proteobacteria,2V0R0@28211|Alphaproteobacteria,2KAP8@204457|Sphingomonadales	204457|Sphingomonadales	S	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
GDHHQS2_k127_1762878_7	697282.Mettu_0616	7.184e-154	495.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
GDHHQS2_k127_1762878_6	765420.OSCT_0207	4.357e-159	520.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_1762878_10	311402.Avi_5350	2.689e-126	413.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,4BBR1@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_1762878_13	926569.ANT_30900	3.117e-110	365.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS2_k127_1762878_44	309807.SRU_1974	1.226e-33	138.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_1762878_67	1051632.TPY_3278	5.907e-05	49.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes	1239|Firmicutes	S	Ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
GDHHQS2_k127_1762878_47	1382356.JQMP01000004_gene590	4.504e-30	123.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GDHHQS2_k127_1762878_52	1120948.KB903218_gene2045	7.952e-22	100.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4E6UD@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM 'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_1762878_50	573370.DMR_23740	6.824e-24	109.0	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GDHHQS2_k127_1762878_42	457396.CSBG_03362	7.806e-37	156.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
GDHHQS2_k127_1762878_29	1304874.JAFY01000007_gene1752	2.22e-51	196.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_1762878_9	926569.ANT_09640	2.074e-140	454.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_1762878_36	880073.Calab_0673	7.457e-42	172.0	COG1262@1|root,COG1262@2|Bacteria,2NR84@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_1762878_65	485913.Krac_8943	5.767e-06	58.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_1762878_22	765420.OSCT_3196	2.731e-71	266.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_1762878_14	357808.RoseRS_4270	2.157e-103	356.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi,376C8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,Wzz
GDHHQS2_k127_1762878_1	1541065.JRFE01000014_gene1505	1.231e-308	1049.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G8F1@1117|Cyanobacteria,3VMVS@52604|Pleurocapsales	1117|Cyanobacteria	M	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
GDHHQS2_k127_1762878_35	395493.BegalDRAFT_1833	3.303e-42	182.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
GDHHQS2_k127_1762878_64	370438.PTH_1010	2.427e-06	61.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,2616T@186807|Peptococcaceae	186801|Clostridia	L	DNA replication protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS2_k127_1762878_61	1170562.Cal6303_0849	1.624e-10	67.0	2BN1K@1|root,32GMS@2|Bacteria,1GKE8@1117|Cyanobacteria,1HT1Y@1161|Nostocales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
GDHHQS2_k127_1762878_54	1183438.GKIL_2163	1.242e-18	88.0	2DRDY@1|root,33BC0@2|Bacteria,1GB4J@1117|Cyanobacteria	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS2_k127_1762878_60	1297617.JPJD01000040_gene3205	6.268e-11	74.0	COG2244@1|root,COG2244@2|Bacteria,1UZ6G@1239|Firmicutes,25FJM@186801|Clostridia,269Q7@186813|unclassified Clostridiales	186801|Clostridia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GDHHQS2_k127_1762878_56	1040986.ATYO01000004_gene4873	2.709e-16	90.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,2U8MR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
GDHHQS2_k127_1762878_27	317936.Nos7107_4509	1.387e-54	214.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1HRUE@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_1762878_58	1120949.KB903305_gene7189	3.718e-16	90.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4D8SQ@85008|Micromonosporales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
GDHHQS2_k127_1762878_15	926569.ANT_07770	3.321e-103	342.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GDHHQS2_k127_1762878_11	926569.ANT_07760	1.229e-119	391.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS2_k127_1762878_55	349161.Dred_0905	2.18e-18	95.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,261TC@186807|Peptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS2_k127_1762878_8	926569.ANT_15960	5.993e-149	480.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
GDHHQS2_k127_1762878_12	926550.CLDAP_39650	2.778e-112	373.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS2_k127_1762878_17	525904.Tter_0486	3.495e-93	317.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS2_k127_1762878_3	926569.ANT_15990	2.582e-297	931.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS2_k127_1762878_40	926550.CLDAP_18590	3.944e-38	151.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS2_k127_1762878_23	1198452.Jab_2c25790	7.372e-68	239.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,2WEJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
GDHHQS2_k127_1762878_16	1221537.B807_603	8.05e-94	318.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K03420,ko:K13525,ko:K17681	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00343,M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147	3.A.16.1	-	-	AAA
GDHHQS2_k127_1762878_2	926569.ANT_20730	6.733e-298	938.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS2_k127_1762878_59	211114.JOEF01000020_gene686	5.854e-12	77.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,2I3FC@201174|Actinobacteria,4EFCV@85010|Pseudonocardiales	201174|Actinobacteria	Q	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_1762878_19	509635.N824_05160	1.176e-86	299.0	COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,1ISPP@117747|Sphingobacteriia	976|Bacteroidetes	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GDHHQS2_k127_1762878_24	926569.ANT_30490	6.156e-67	239.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS2_k127_1762878_5	255470.cbdbA1399	1.955e-173	567.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi,34CJB@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Telomere recombination	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GDHHQS2_k127_1762878_46	926569.ANT_16430	1.232e-31	128.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1762878_0	292415.Tbd_0234	0.0	1658.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KRGX@119069|Hydrogenophilales	119069|Hydrogenophilales	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS2_k127_1762878_43	1280947.HY30_03525	4.774e-36	147.0	COG3551@1|root,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,TPR_19
GDHHQS2_k127_1762878_45	867845.KI911784_gene2277	9.951e-33	142.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
GDHHQS2_k127_1762878_25	861299.J421_1182	4.37e-60	215.0	COG2267@1|root,COG2267@2|Bacteria,1ZTW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1762878_69	743719.PaelaDRAFT_3658	0.0002828	52.0	2E0MC@1|root,32W6K@2|Bacteria,1VDT9@1239|Firmicutes,4HQHS@91061|Bacilli,26S1C@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1762878_66	1077972.ARGLB_054_00510	2.976e-05	56.0	COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,1WAQV@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_1762878_51	1392490.JHZX01000001_gene328	6.372e-23	102.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
GDHHQS2_k127_1819201_50	1338011.BD94_1312	2.838e-24	104.0	COG2169@1|root,COG2169@2|Bacteria,4NV90@976|Bacteroidetes,1I5VR@117743|Flavobacteriia,34RQW@308865|Elizabethkingia	976|Bacteroidetes	F	Metal binding domain of Ada	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
GDHHQS2_k127_1819201_40	273068.TTE0112	1.502e-37	160.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,42ETJ@68295|Thermoanaerobacterales	186801|Clostridia	S	G5 domain protein	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
GDHHQS2_k127_1819201_31	118168.MC7420_7034	5.006e-50	186.0	COG3145@1|root,COG3145@2|Bacteria,1G7J2@1117|Cyanobacteria,1HFG8@1150|Oscillatoriales	1117|Cyanobacteria	L	Alkylated DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
GDHHQS2_k127_1819201_22	926560.KE387027_gene397	4.217e-85	290.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS2_k127_1819201_20	1128421.JAGA01000002_gene351	2.771e-88	303.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS2_k127_1819201_10	926569.ANT_15200	1.093e-109	366.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GDHHQS2_k127_1819201_64	28042.GU90_06645	3.682e-06	55.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DYVD@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
GDHHQS2_k127_1819201_45	1205680.CAKO01000035_gene316	1.578e-27	118.0	COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,2UFGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_1819201_37	926569.ANT_14100	1.097e-42	172.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS2_k127_1819201_24	1173263.Syn7502_01411	3.288e-68	246.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ETR2	-	1.8.1.9,3.1.3.3	ko:K00384,ko:K07315	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_1819201_30	395493.BegalDRAFT_0733	1.74e-54	205.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_1819201_51	469383.Cwoe_1551	4.936e-23	113.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_1819201_59	357808.RoseRS_4300	1.337e-08	68.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,376E7@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_1819201_0	518766.Rmar_2224	1.27e-189	601.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_1819201_68	926550.CLDAP_35190	0.000776	48.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_1	357808.RoseRS_2356	8.937e-165	531.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Arylsulfotran_2,UnbV_ASPIC,VCBS
GDHHQS2_k127_1819201_28	383372.Rcas_3070	1.686e-55	206.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS2_k127_1819201_48	765420.OSCT_2689	1.263e-26	120.0	COG4632@1|root,COG4632@2|Bacteria,2G8RE@200795|Chloroflexi,375J8@32061|Chloroflexia	32061|Chloroflexia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GDHHQS2_k127_1819201_18	485916.Dtox_2632	5.482e-95	322.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GDHHQS2_k127_1819201_55	1280666.ATVS01000002_gene2924	2.847e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1TRS2@1239|Firmicutes,24AF1@186801|Clostridia,4BYVA@830|Butyrivibrio	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_1819201_17	926569.ANT_06750	5.415e-97	332.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS2_k127_1819201_11	477974.Daud_0129	8.64e-108	362.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,260YM@186807|Peptococcaceae	186801|Clostridia	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
GDHHQS2_k127_1819201_34	485913.Krac_5198	4.814e-45	168.0	2EF1Q@1|root,307CD@2|Bacteria,2G9P0@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_9	383372.Rcas_2285	1.438e-113	377.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi,3756Q@32061|Chloroflexia	32061|Chloroflexia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS2_k127_1819201_54	1173029.JH980292_gene614	5.288e-21	104.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GDHHQS2_k127_1819201_39	1522072.IL54_0233	4.836e-38	152.0	28NZE@1|root,2ZBWC@2|Bacteria,1N7IG@1224|Proteobacteria,2UPC8@28211|Alphaproteobacteria,2K5EZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_58	861299.J421_1582	2.249e-12	72.0	2ETJB@1|root,33M34@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
GDHHQS2_k127_1819201_15	479434.Sthe_3148	2.231e-98	335.0	COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi	200795|Chloroflexi	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_21	243233.MCA1900	9.074e-86	294.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XF2R@135618|Methylococcales	135618|Methylococcales	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS2_k127_1819201_8	1449069.JMLO01000013_gene1217	3.076e-121	400.0	COG2132@1|root,COG2132@2|Bacteria,2GPUP@201174|Actinobacteria,4FYPQ@85025|Nocardiaceae	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
GDHHQS2_k127_1819201_5	177437.HRM2_23280	2.909e-133	443.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2MI5B@213118|Desulfobacterales	68525|delta/epsilon subdivisions	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_1819201_3	926569.ANT_23340	1.379e-140	461.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_1819201_12	926569.ANT_23350	2.766e-107	359.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS2_k127_1819201_7	926560.KE387023_gene3344	1.349e-123	405.0	2DBC8@1|root,2Z8C9@2|Bacteria,1WKX1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_57	368407.Memar_1051	7.903e-13	74.0	COG3187@1|root,arCOG03952@2157|Archaea,2Y55P@28890|Euryarchaeota,2NBFA@224756|Methanomicrobia	224756|Methanomicrobia	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
GDHHQS2_k127_1819201_60	571166.KI421509_gene1258	2.11e-07	60.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N8AF@1224|Proteobacteria,2UGPH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Protein conserved in bacteria	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GDHHQS2_k127_1819201_56	317936.Nos7107_0424	9.983e-17	85.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1HNCP@1161|Nostocales	1117|Cyanobacteria	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS2_k127_1819201_67	106648.BBLJ01000007_gene420	0.0005955	49.0	2DM7U@1|root,323KQ@2|Bacteria,1RJC0@1224|Proteobacteria,1S797@1236|Gammaproteobacteria,3NKME@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_26	926569.ANT_06790	1.035e-62	224.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS2_k127_1819201_19	926569.ANT_06780	7.848e-90	298.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
GDHHQS2_k127_1819201_27	926569.ANT_06770	1.793e-62	224.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_1819201_42	1242864.D187_001257	1.922e-33	140.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,42WIT@68525|delta/epsilon subdivisions,2X0TU@28221|Deltaproteobacteria,2Z2N8@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_1819201_25	1128421.JAGA01000002_gene788	1.079e-63	231.0	COG0030@1|root,COG0030@2|Bacteria,2NPDT@2323|unclassified Bacteria	2|Bacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS2_k127_1819201_53	46234.ANA_C13708	4.454e-21	106.0	COG0251@1|root,COG1357@1|root,COG0251@2|Bacteria,COG1357@2|Bacteria,1G6TD@1117|Cyanobacteria,1HK8V@1161|Nostocales	1117|Cyanobacteria	J	TIGRFAM endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Pentapeptide,Ribonuc_L-PSP
GDHHQS2_k127_1819201_4	1231241.Mc24_06453	3.733e-138	451.0	COG0334@1|root,COG0334@2|Bacteria,2GCH4@200918|Thermotogae	200918|Thermotogae	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iLJ478.TM1015	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS2_k127_1819201_52	28564.XP_002488371.1	4.36e-22	112.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3RN16@4890|Ascomycota,20UKC@147545|Eurotiomycetes,3SE9V@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,HET,NACHT,WD40
GDHHQS2_k127_1819201_62	383372.Rcas_1659	4.049e-07	60.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_44	926569.ANT_20740	1.452e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_1819201_65	326427.Cagg_1239	3.988e-06	58.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_61	32057.KB217478_gene5303	2.148e-07	59.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMFH@1161|Nostocales	1117|Cyanobacteria	CT	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
GDHHQS2_k127_1819201_66	292459.STH989	0.000163	54.0	COG1686@1|root,COG3103@1|root,COG1686@2|Bacteria,COG4991@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
GDHHQS2_k127_1819201_6	204669.Acid345_3113	4.928e-125	413.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS2_k127_1819201_43	329726.AM1_1952	2.046e-33	136.0	2EDEG@1|root,337AV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1819201_32	1121904.ARBP01000003_gene6175	2.501e-47	175.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,47QYV@768503|Cytophagia	976|Bacteroidetes	S	COGs COG3797 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS2_k127_1819201_36	756067.MicvaDRAFT_3766	1.088e-43	167.0	COG3124@1|root,COG3124@2|Bacteria,1G626@1117|Cyanobacteria,1HBJJ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Acyl carrier protein phosphodiesterase	-	-	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	-	ACP_PD
GDHHQS2_k127_1819201_47	300852.55772280	1.054e-26	112.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GDHHQS2_k127_1819201_46	65093.PCC7418_1385	2.573e-27	112.0	COG1724@1|root,COG1724@2|Bacteria,1G7S1@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_1819201_49	111780.Sta7437_3635	7.261e-26	108.0	COG1598@1|root,COG1598@2|Bacteria,1GF2K@1117|Cyanobacteria,3VKUB@52604|Pleurocapsales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_1819201_13	404380.Gbem_0736	7.245e-107	357.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WJQV@28221|Deltaproteobacteria,43S19@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_1819201_33	926550.CLDAP_20100	1.664e-46	174.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS2_k127_1819201_2	926550.CLDAP_20090	2.016e-144	475.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3585	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
GDHHQS2_k127_1819201_41	926550.CLDAP_20080	2.139e-34	144.0	COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_1819201_23	330214.NIDE2777	4.27e-78	271.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GDHHQS2_k127_1819201_38	357808.RoseRS_3747	9.757e-42	162.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_1819201_29	867845.KI911784_gene1050	2.828e-55	199.0	2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi,377IA@32061|Chloroflexia	32061|Chloroflexia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_1819201_16	56107.Cylst_1884	2.523e-97	332.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
GDHHQS2_k127_1819201_14	867845.KI911784_gene2182	8.086e-101	344.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GDHHQS2_k127_1819201_35	926569.ANT_05550	5.25e-44	177.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K15770	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_1961484_0	926569.ANT_08650	8.573e-163	524.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS2_k127_1961484_2	765420.OSCT_1027	1.892e-81	288.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,3752J@32061|Chloroflexia	32061|Chloroflexia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_1961484_4	5741.EDO81512	3.964e-40	153.0	COG0295@1|root,KOG0833@2759|Eukaryota	2759|Eukaryota	F	cytidine deaminase activity	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	EF-hand_5,EF-hand_7,SAM_1,SAM_2,dCMP_cyt_deam_1,dCMP_cyt_deam_2
GDHHQS2_k127_1961484_3	1128421.JAGA01000002_gene486	7.146e-68	239.0	COG1381@1|root,COG1381@2|Bacteria,2NPV3@2323|unclassified Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS2_k127_1961484_8	765420.OSCT_2978	9.649e-16	81.0	28VCT@1|root,2ZHFH@2|Bacteria,2GB88@200795|Chloroflexi,377J8@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_1961484_1	1173028.ANKO01000017_gene192	1.097e-98	328.0	COG0455@1|root,COG0455@2|Bacteria,1G1EJ@1117|Cyanobacteria,1H7J7@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
GDHHQS2_k127_1961484_7	1173028.ANKO01000041_gene3216	4.363e-31	137.0	COG0664@1|root,COG0664@2|Bacteria,1GEZE@1117|Cyanobacteria	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS2_k127_1961484_10	304371.MCP_1275	6.68e-09	68.0	COG2339@1|root,arCOG05366@1|root,arCOG02985@2157|Archaea,arCOG05366@2157|Archaea,2Y73S@28890|Euryarchaeota,2NB99@224756|Methanomicrobia	224756|Methanomicrobia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GDHHQS2_k127_1961484_6	555079.Toce_1274	2.137e-36	144.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_1961484_9	1484479.DI14_05515	3.464e-14	82.0	COG0726@1|root,COG1388@1|root,COG0726@2|Bacteria,COG1388@2|Bacteria,1V6DN@1239|Firmicutes,4HCJW@91061|Bacilli,3WFKX@539002|Bacillales incertae sedis	91061|Bacilli	GM	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Cu_amine_oxidN1,LysM,Polysacc_deac_1
GDHHQS2_k127_1961484_5	383372.Rcas_2148	2.685e-39	157.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_2030911_59	37919.EP51_28215	4.787e-18	89.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria,4G7KG@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS2_k127_2030911_7	926569.ANT_25960	1.96e-144	465.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS2_k127_2030911_45	886293.Sinac_3291	1.28e-28	123.0	COG4636@1|root,COG4636@2|Bacteria,2J0XX@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_2030911_63	1170562.Cal6303_2865	1.531e-14	87.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GDHHQS2_k127_2030911_60	746697.Aeqsu_0765	4.168e-17	86.0	COG5649@1|root,COG5649@2|Bacteria,4NPG5@976|Bacteroidetes,1I4MN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_2030911_33	1120959.ATXF01000005_gene1091	2.023e-50	186.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yokL3	-	2.3.1.57	ko:K00657,ko:K07023	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
GDHHQS2_k127_2030911_9	357808.RoseRS_0088	1.889e-139	456.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,375DN@32061|Chloroflexia	32061|Chloroflexia	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_2030911_16	1121378.KB899696_gene2639	2.155e-81	275.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_2030911_39	1294142.CINTURNW_2220	2.709e-35	142.0	COG1573@1|root,COG1573@2|Bacteria,1V58R@1239|Firmicutes,248TH@186801|Clostridia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
GDHHQS2_k127_2030911_34	290397.Adeh_0115	3.399e-48	196.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2030911_57	926550.CLDAP_12370	8.863e-19	102.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_29	903818.KI912268_gene669	5.933e-58	213.0	COG2324@1|root,COG2324@2|Bacteria	2|Bacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
GDHHQS2_k127_2030911_22	903818.KI912268_gene670	1.706e-71	251.0	COG2324@1|root,COG2324@2|Bacteria,3Y7JJ@57723|Acidobacteria	57723|Acidobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
GDHHQS2_k127_2030911_61	118163.Ple7327_4371	2.597e-16	89.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS2_k127_2030911_13	1462527.CCDM010000001_gene2800	2.3e-104	358.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4HBRJ@91061|Bacilli,23IW7@182709|Oceanobacillus	91061|Bacilli	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_2030911_19	1173027.Mic7113_4161	2.82e-77	287.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_2030911_5	926569.ANT_15620	9.881e-186	595.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS2_k127_2030911_53	1382306.JNIM01000001_gene3987	3.811e-23	113.0	COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi	200795|Chloroflexi	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
GDHHQS2_k127_2030911_25	1499967.BAYZ01000074_gene2129	2e-65	229.0	COG0503@1|root,COG0503@2|Bacteria	2|Bacteria	F	purine ribonucleoside salvage	xpt	GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147	-	-	iYO844.BSU22070	Pribosyltran
GDHHQS2_k127_2030911_3	326427.Cagg_1667	3.128e-207	656.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,374SN@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C
GDHHQS2_k127_2030911_27	1265505.ATUG01000002_gene1702	4.344e-61	224.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42UHV@68525|delta/epsilon subdivisions,2WQCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
GDHHQS2_k127_2030911_28	926569.ANT_15640	2.572e-59	218.0	COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS2_k127_2030911_56	864702.OsccyDRAFT_2681	4.866e-20	90.0	COG1598@1|root,COG1598@2|Bacteria,1G7N4@1117|Cyanobacteria,1HDCI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_2030911_11	357808.RoseRS_0270	1.402e-111	379.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS2_k127_2030911_10	1444309.JAQG01000164_gene1837	3.473e-134	445.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
GDHHQS2_k127_2030911_62	309801.trd_0602	4.115e-16	85.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
GDHHQS2_k127_2030911_73	649638.Trad_2805	0.0001627	48.0	COG2010@1|root,COG3125@1|root,COG2010@2|Bacteria,COG3125@2|Bacteria,1WJSY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS2_k127_2030911_40	649638.Trad_2804	1.23e-34	140.0	COG1845@1|root,COG1845@2|Bacteria,1WJ6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG1845 Heme copper-type cytochrome quinol oxidase subunit 3	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS2_k127_2030911_72	1313172.YM304_38670	1.303e-05	50.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CMUD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_2030911_30	1128421.JAGA01000003_gene2726	2.691e-56	206.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GDHHQS2_k127_2030911_47	113355.CM001775_gene2248	7.941e-27	117.0	COG1845@1|root,COG1845@2|Bacteria,1G02A@1117|Cyanobacteria	1117|Cyanobacteria	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS2_k127_2030911_2	383372.Rcas_3557	8.699e-215	679.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS2_k127_2030911_20	479434.Sthe_1582	4.782e-77	270.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS2_k127_2030911_26	765420.OSCT_1574	3.627e-64	241.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_2030911_50	497321.C664_07233	3.685e-25	106.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VU78@28216|Betaproteobacteria,2KX1D@206389|Rhodocyclales	206389|Rhodocyclales	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GDHHQS2_k127_2030911_4	595494.Tola_1002	2.986e-196	623.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1S0YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
GDHHQS2_k127_2030911_69	1123360.thalar_02468	4.36e-06	52.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2UG4S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_42	926550.CLDAP_10030	5.971e-33	142.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_2030911_0	926550.CLDAP_06400	1.061e-251	797.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS2_k127_2030911_64	1041930.Mtc_1167	1.608e-12	74.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota,2N9SE@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GDHHQS2_k127_2030911_37	324602.Caur_0298	3.218e-37	163.0	COG0823@1|root,COG3210@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_43	1443665.JACA01000052_gene1878	9.054e-30	139.0	COG0726@1|root,COG2730@1|root,COG3250@1|root,COG4733@1|root,COG0726@2|Bacteria,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,F5_F8_type_C,fn3
GDHHQS2_k127_2030911_48	485913.Krac_4272	1.2e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,2G9DR@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2030911_38	926569.ANT_16430	4.638e-37	146.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_41	926569.ANT_16430	2.334e-34	136.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_21	926569.ANT_16610	3.037e-74	255.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS2_k127_2030911_65	1122929.KB908238_gene1361	1.859e-12	76.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2U98F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
GDHHQS2_k127_2030911_31	452652.KSE_62270	3.184e-55	217.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,2M4CV@2063|Kitasatospora	201174|Actinobacteria	O	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
GDHHQS2_k127_2030911_36	483219.LILAB_15170	1.045e-39	150.0	COG4539@1|root,COG4539@2|Bacteria,1NXWT@1224|Proteobacteria,4384M@68525|delta/epsilon subdivisions,2X9XD@28221|Deltaproteobacteria,2YVQP@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GDHHQS2_k127_2030911_24	926569.ANT_27050	6.453e-69	239.0	COG1695@1|root,COG1695@2|Bacteria,2G9N5@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GDHHQS2_k127_2030911_14	926569.ANT_27060	5.603e-103	340.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_2030911_51	765420.OSCT_2140	4.915e-25	117.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS2_k127_2030911_1	926569.ANT_27070	1.117e-244	781.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_2030911_46	547163.BN979_04869	7.014e-27	115.0	COG0607@1|root,COG0607@2|Bacteria,2IIT0@201174|Actinobacteria,239PK@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_2030911_66	1303518.CCALI_00738	3.56e-10	65.0	2EHSB@1|root,33BI2@2|Bacteria	2|Bacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
GDHHQS2_k127_2030911_44	926569.ANT_06890	5.016e-29	124.0	2ECEX@1|root,336D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2030911_32	706587.Desti_2993	8.649e-52	186.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS2_k127_2030911_15	706587.Desti_2992	6.124e-101	340.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria	1224|Proteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2030911_76	401053.AciPR4_0456	0.0006314	45.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
GDHHQS2_k127_2030911_18	251221.35211202	7.522e-79	282.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
GDHHQS2_k127_2030911_8	926569.ANT_00530	5.358e-140	464.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
GDHHQS2_k127_2030911_55	926550.CLDAP_14760	2.58e-20	98.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
GDHHQS2_k127_2030911_23	926550.CLDAP_14750	5.177e-70	247.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS2_k127_2030911_12	1123276.KB893301_gene4189	6.445e-107	362.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,47M51@768503|Cytophagia	976|Bacteroidetes	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
GDHHQS2_k127_2030911_71	913325.N799_09330	6.514e-06	59.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PYUK@1224|Proteobacteria,1S0VV@1236|Gammaproteobacteria,1X5W9@135614|Xanthomonadales	135614|Xanthomonadales	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS2_k127_2030911_67	926569.ANT_01080	2.025e-09	60.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS2_k127_2030911_49	391612.CY0110_26712	6.428e-26	108.0	COG1598@1|root,COG1598@2|Bacteria,1G9MA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_2030911_54	46234.ANA_C10011	4.112e-22	98.0	COG1724@1|root,COG1724@2|Bacteria,1G890@1117|Cyanobacteria	1117|Cyanobacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_2030911_6	502025.Hoch_4658	1.467e-158	527.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
GDHHQS2_k127_2030911_52	362418.IW19_07925	6.492e-25	109.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I2SV@117743|Flavobacteriia,2P0MB@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_2030911_68	869210.Marky_2012	4.585e-09	63.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	soxX	-	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cytochrom_C
GDHHQS2_k127_2030911_70	338969.Rfer_3822	5.826e-06	57.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_2071740_9	316274.Haur_3216	2.082e-23	100.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi,375CU@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS2_k127_2071740_4	926569.ANT_08360	6.821e-126	411.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS2_k127_2071740_0	926569.ANT_08350	9.67e-240	768.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS2_k127_2071740_2	926569.ANT_08340	6.129e-156	503.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS2_k127_2071740_7	926569.ANT_08330	7.191e-45	168.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS2_k127_2071740_1	926569.ANT_08320	1.121e-176	562.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS2_k127_2071740_8	1379698.RBG1_1C00001G1052	2.885e-44	167.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
GDHHQS2_k127_2071740_5	926569.ANT_08300	3.261e-90	300.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS2_k127_2071740_3	706587.Desti_3108	5.274e-150	484.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,43DQP@68525|delta/epsilon subdivisions,2X6VW@28221|Deltaproteobacteria,2MR1H@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
GDHHQS2_k127_2071740_6	1499967.BAYZ01000171_gene5573	1.903e-72	258.0	COG0075@1|root,COG0075@2|Bacteria	2|Bacteria	E	2-aminoethylphosphonate-pyruvate transaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_2076093_0	926569.ANT_03160	6.331e-186	597.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS2_k127_2076093_1	926569.ANT_16550	8.28e-139	450.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_2076093_4	1121405.dsmv_3084	6.35e-67	244.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2076093_11	234267.Acid_7571	2.098e-06	60.0	COG0823@1|root,COG0823@2|Bacteria,3Y95P@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_2076093_8	933262.AXAM01000128_gene1034	3.262e-21	106.0	COG1714@1|root,COG1714@2|Bacteria,1RFCE@1224|Proteobacteria,433E9@68525|delta/epsilon subdivisions,2WXA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS2_k127_2076093_10	485913.Krac_2843	2.182e-08	65.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_2076093_3	1128421.JAGA01000002_gene1156	2.173e-70	249.0	COG1284@1|root,COG1284@2|Bacteria,2NPQD@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
GDHHQS2_k127_2076093_6	869210.Marky_1511	8.194e-33	137.0	COG1528@1|root,COG1528@2|Bacteria,1WK4S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Iron-storage protein	-	-	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GDHHQS2_k127_2076093_2	485913.Krac_7522	6.121e-136	440.0	COG1830@1|root,COG1830@2|Bacteria,2G8VI@200795|Chloroflexi	200795|Chloroflexi	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GDHHQS2_k127_2076093_7	330214.NIDE0017	1.431e-29	119.0	COG3369@1|root,COG3369@2|Bacteria,3J1A6@40117|Nitrospirae	40117|Nitrospirae	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS2_k127_2076093_5	386456.JQKN01000005_gene441	2.264e-62	224.0	arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_2076093_9	314345.SPV1_03143	2.035e-18	88.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_2373030_187	533240.CRC_03061	4.302e-07	60.0	COG1357@1|root,COG1357@2|Bacteria,1G7BD@1117|Cyanobacteria,1HNUV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_2373030_197	485913.Krac_2785	1.083e-05	51.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	HNH,RRXRR
GDHHQS2_k127_2373030_164	1048834.TC41_2504	6.761e-18	92.0	2BH1N@1|root,32B21@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_152	697281.Mahau_2392	1.585e-23	112.0	COG0443@1|root,COG0443@2|Bacteria,1V76M@1239|Firmicutes,24GMR@186801|Clostridia,42G24@68295|Thermoanaerobacterales	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
GDHHQS2_k127_2373030_56	78245.Xaut_1087	2.315e-86	312.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria	1224|Proteobacteria	L	AAA domain	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_2,Prim_Zn_Ribbon,Toprim_3
GDHHQS2_k127_2373030_181	382640.pBT01_0016	6.236e-09	69.0	COG0358@1|root,COG0358@2|Bacteria,1R5JV@1224|Proteobacteria,2TW8V@28211|Alphaproteobacteria,48TG2@772|Bartonellaceae	28211|Alphaproteobacteria	L	Toprim domain	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_3
GDHHQS2_k127_2373030_31	195253.Syn6312_0385	3.414e-124	408.0	COG0498@1|root,COG0498@2|Bacteria,1G31E@1117|Cyanobacteria,1GYCG@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_2373030_142	1120934.KB894405_gene5372	1.14e-30	139.0	COG1361@1|root,COG1361@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
GDHHQS2_k127_2373030_68	326427.Cagg_2009	1.645e-78	289.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,2GA9R@200795|Chloroflexi,374ZK@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,dCache_3
GDHHQS2_k127_2373030_179	1150469.RSPPHO_00735	3.037e-10	66.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2U2AJ@28211|Alphaproteobacteria,2JQMF@204441|Rhodospirillales	204441|Rhodospirillales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
GDHHQS2_k127_2373030_134	1242864.D187_008946	3.55e-33	143.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,43AYG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_2373030_126	926569.ANT_18500	8.636e-37	152.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_2373030_27	316274.Haur_3506	3.056e-128	419.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,3750N@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS2_k127_2373030_169	316274.Haur_3505	7.679e-14	81.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,375TM@32061|Chloroflexia	32061|Chloroflexia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS2_k127_2373030_23	926569.ANT_23450	8.073e-131	430.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS2_k127_2373030_20	926569.ANT_23460	1.866e-138	450.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS2_k127_2373030_196	479434.Sthe_2118	7.013e-06	57.0	2ATQQ@1|root,31J9F@2|Bacteria,2GA4K@200795|Chloroflexi,27Z84@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_16	1499967.BAYZ01000116_gene3144	5.686e-169	547.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	BLUF,GAF_2,GAF_3,Guanylate_cyc,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2373030_11	1242864.D187_001830	4.804e-193	640.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_2373030_15	1242864.D187_001830	1.537e-175	588.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_2373030_65	555079.Toce_0685	1.085e-78	280.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_2373030_70	665952.HMPREF1015_02266	4.655e-73	256.0	COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,1ZD0Z@1386|Bacillus	91061|Bacilli	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
GDHHQS2_k127_2373030_103	1051632.TPY_1315	1.232e-49	181.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WDEN@538999|Clostridiales incertae sedis	186801|Clostridia	T	Low molecular weight phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS2_k127_2373030_1	926569.ANT_23480	0.0	1088.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GDHHQS2_k127_2373030_122	1407650.BAUB01000038_gene2918	8.556e-38	146.0	2CFUA@1|root,32S2G@2|Bacteria,1G7BR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_130	862908.BMS_0818	1.786e-35	140.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,42UWP@68525|delta/epsilon subdivisions,2MUMA@213481|Bdellovibrionales,2WRE4@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Small Multidrug Resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
GDHHQS2_k127_2373030_8	1267535.KB906767_gene2200	1.221e-210	664.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_2373030_41	765420.OSCT_0421	1.706e-106	353.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS2_k127_2373030_95	525904.Tter_1742	3.714e-54	216.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2373030_170	1125971.ASJB01000042_gene3420	2.068e-13	83.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11,Yop-YscD_cpl
GDHHQS2_k127_2373030_151	649638.Trad_1325	8.547e-24	110.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	rsmD	-	2.1.1.171	ko:K08316,ko:K15257	-	-	R07234	RC00003	ko00000,ko01000,ko03009,ko03016	-	-	-	Cons_hypoth95
GDHHQS2_k127_2373030_139	1007103.AFHW01000138_gene1457	7.192e-32	132.0	COG5628@1|root,COG5628@2|Bacteria,1VAGU@1239|Firmicutes,4HHK0@91061|Bacilli,26QQ8@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_2373030_63	926569.ANT_13390	9.918e-81	274.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS2_k127_2373030_85	1200792.AKYF01000012_gene1279	5.946e-61	218.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_2373030_124	326427.Cagg_2243	5.081e-37	149.0	2BK2H@1|root,32EFV@2|Bacteria	2|Bacteria	L	Restriction endonuclease BglII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuc-BglII
GDHHQS2_k127_2373030_107	525904.Tter_1740	6.435e-45	175.0	COG1277@1|root,COG1277@2|Bacteria,2NRHU@2323|unclassified Bacteria	2|Bacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
GDHHQS2_k127_2373030_148	867845.KI911784_gene3519	8.525e-26	123.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_34	383372.Rcas_3818	2.557e-120	394.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_2373030_82	357808.RoseRS_1889	2.727e-63	228.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_2373030_44	383372.Rcas_3820	6.783e-104	361.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
GDHHQS2_k127_2373030_154	1002809.SSIL_1862	3.03e-23	107.0	COG1051@1|root,COG1051@2|Bacteria,1V9D6@1239|Firmicutes,4HICH@91061|Bacilli	91061|Bacilli	F	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_2373030_14	1128421.JAGA01000003_gene3234	2.211e-178	593.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
GDHHQS2_k127_2373030_71	485913.Krac_3240	1.024e-72	258.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
GDHHQS2_k127_2373030_114	765420.OSCT_2689	9.389e-42	165.0	COG4632@1|root,COG4632@2|Bacteria,2G8RE@200795|Chloroflexi,375J8@32061|Chloroflexia	32061|Chloroflexia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GDHHQS2_k127_2373030_75	1455608.JDTH01000001_gene3705	3.039e-70	253.0	COG3608@1|root,arCOG02890@2157|Archaea,2XUVB@28890|Euryarchaeota,23UWM@183963|Halobacteria	183963|Halobacteria	S	Deacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
GDHHQS2_k127_2373030_136	926550.CLDAP_37290	2.492e-32	135.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_2373030_90	272123.Anacy_3707	2.212e-58	222.0	COG2319@1|root,COG4248@1|root,COG2319@2|Bacteria,COG4248@2|Bacteria,1G1D0@1117|Cyanobacteria,1HM57@1161|Nostocales	1117|Cyanobacteria	S	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
GDHHQS2_k127_2373030_102	1499967.BAYZ01000090_gene4936	4.605e-50	203.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_2373030_153	177437.HRM2_24560	2.401e-23	111.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,42PGE@68525|delta/epsilon subdivisions,2WMNI@28221|Deltaproteobacteria,2MJM6@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	PFAM aminotransferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_2373030_48	326427.Cagg_1901	6.962e-96	330.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_2373030_110	926569.ANT_06810	1.434e-42	164.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_171	926569.ANT_13230	5.012e-13	75.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS2_k127_2373030_194	1173021.ALWA01000019_gene527	1.449e-06	58.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_2373030_198	926550.CLDAP_00160	2.392e-05	56.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GDHHQS2_k127_2373030_0	357808.RoseRS_2190	0.0	1283.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
GDHHQS2_k127_2373030_58	1128912.GMES_2010	3.294e-86	296.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,4670H@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
GDHHQS2_k127_2373030_54	926569.ANT_22600	1.047e-90	313.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GDHHQS2_k127_2373030_168	485913.Krac_5906	1.1e-15	83.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GDHHQS2_k127_2373030_66	926550.CLDAP_31480	1.313e-78	274.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GDHHQS2_k127_2373030_208	1198114.AciX9_2879	0.0008082	51.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y2WK@57723|Acidobacteria,2JIVV@204432|Acidobacteriia	204432|Acidobacteriia	M	Tricorn protease C1 domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ,Peptidase_S41,Tricorn_C1
GDHHQS2_k127_2373030_123	1128421.JAGA01000002_gene1899	4.252e-37	143.0	COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS2_k127_2373030_39	926569.ANT_10420	4.708e-111	372.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS2_k127_2373030_163	84588.SYNW2272	2.267e-18	91.0	COG0839@1|root,COG0839@2|Bacteria,1G2WH@1117|Cyanobacteria,1GYUG@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
GDHHQS2_k127_2373030_140	1173264.KI913949_gene1311	1.785e-31	125.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,1HBH9@1150|Oscillatoriales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
GDHHQS2_k127_2373030_6	926569.ANT_10450	3.055e-223	716.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GDHHQS2_k127_2373030_13	926569.ANT_10460	1.15e-188	602.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS2_k127_2373030_24	264732.Moth_0986	1.057e-129	432.0	COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,24AAH@186801|Clostridia,42FG3@68295|Thermoanaerobacterales	186801|Clostridia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS2_k127_2373030_37	926569.ANT_10480	4.013e-113	382.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS2_k127_2373030_128	255470.cbdbA532	2.065e-36	152.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,34D35@301297|Dehalococcoidia	301297|Dehalococcoidia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS2_k127_2373030_165	926569.ANT_10530	1.567e-16	81.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS2_k127_2373030_135	926569.ANT_10540	1.668e-32	135.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS2_k127_2373030_19	926569.ANT_10550	2.167e-145	477.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_2373030_22	926550.CLDAP_31450	7.059e-133	441.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G5Y5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS2_k127_2373030_88	357808.RoseRS_3452	9.156e-59	213.0	COG3275@1|root,COG3275@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.65	ko:K16923,ko:K18967	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.28,9.B.34.1.1	-	-	5TM-5TMR_LYT,ECF_trnsprt,GGDEF,HATPase_c,PAS_4,PAS_7
GDHHQS2_k127_2373030_94	1128421.JAGA01000001_gene2132	7.45e-55	202.0	COG0619@1|root,COG0619@2|Bacteria,2NR9U@2323|unclassified Bacteria	2|Bacteria	P	Cobalt transport protein	-	-	-	ko:K02008,ko:K16785	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS2_k127_2373030_61	1128421.JAGA01000001_gene2131	1.346e-84	290.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS2_k127_2373030_57	312284.A20C1_06196	3.138e-86	293.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,3UXBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
GDHHQS2_k127_2373030_53	521011.Mpal_1744	8.409e-91	314.0	COG1812@1|root,arCOG01678@2157|Archaea,2XT7J@28890|Euryarchaeota,2N9CD@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the formation of S-adenosylmethionine from methionine and ATP	mat	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
GDHHQS2_k127_2373030_144	926569.ANT_14050	4.451e-28	120.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS2_k127_2373030_185	864073.HFRIS_017002	5.533e-08	65.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,4771B@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_2373030_120	58123.JOFJ01000008_gene378	4.856e-38	145.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4EKCA@85012|Streptosporangiales	201174|Actinobacteria	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS2_k127_2373030_192	926550.CLDAP_12350	1.095e-06	62.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GDHHQS2_k127_2373030_129	926550.CLDAP_35480	7.196e-36	158.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
GDHHQS2_k127_2373030_101	296587.XP_002505358.1	1.741e-50	197.0	COG0366@1|root,KOG0471@2759|Eukaryota,3845B@33090|Viridiplantae,34NH1@3041|Chlorophyta	2759|Eukaryota	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20
GDHHQS2_k127_2373030_106	926569.ANT_06560	6.82e-46	185.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GDHHQS2_k127_2373030_45	383372.Rcas_0204	4.082e-103	347.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi,375E3@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_2373030_26	926550.CLDAP_39770	1.797e-129	421.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_2373030_51	316274.Haur_3900	1.483e-93	316.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2373030_201	69014.TK0232	5.392e-05	54.0	COG0454@1|root,arCOG00845@2157|Archaea,2Y67B@28890|Euryarchaeota,2430F@183968|Thermococci	183968|Thermococci	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_2373030_5	1430331.EP10_17210	3.536e-225	721.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1WFAI@129337|Geobacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS2_k127_2373030_147	309801.trd_0624	8.232e-27	111.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi,27YK2@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS2_k127_2373030_203	1206741.BAFX01000049_gene2186	0.0001019	51.0	COG0348@1|root,COG1716@1|root,COG0348@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	EAL,EF-hand_7,FHA,Fer2,Fer4_5,Pyr_redox_2,Yop-YscD_cpl,cNMP_binding
GDHHQS2_k127_2373030_72	1278073.MYSTI_02808	1.583e-71	252.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
GDHHQS2_k127_2373030_7	926569.ANT_10600	8.654e-213	673.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GDHHQS2_k127_2373030_121	316274.Haur_0023	8.289e-38	164.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_2373030_132	330214.NIDE1115	6.507e-34	151.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Trypsin_2
GDHHQS2_k127_2373030_111	485913.Krac_0934	1.685e-42	167.0	COG4759@1|root,COG4759@2|Bacteria	2|Bacteria	O	protein conserved in bacteria containing thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
GDHHQS2_k127_2373030_80	1089551.KE386572_gene3286	4.632e-66	233.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VFPM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_2373030_176	743299.Acife_2025	1.709e-11	69.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,2NDAI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_2373030_42	926569.ANT_12630	7.754e-105	349.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS2_k127_2373030_55	926550.CLDAP_14970	6.767e-89	304.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS2_k127_2373030_92	525904.Tter_1673	6.302e-57	200.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS2_k127_2373030_202	479431.Namu_1594	9.764e-05	46.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria,4ETJU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_131	926569.ANT_18470	3.098e-35	144.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS2_k127_2373030_96	926569.ANT_18490	9.454e-54	199.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS2_k127_2373030_97	926569.ANT_30130	5.091e-53	201.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_2373030_100	926569.ANT_15760	1.56e-50	194.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS2_k127_2373030_119	926569.ANT_30130	1.157e-38	159.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_2373030_3	926569.ANT_25700	5.456e-260	849.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_2373030_77	926569.ANT_24880	3.144e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,2G8EM@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_2373030_157	760192.Halhy_1275	2.46e-22	101.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1ITPQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
GDHHQS2_k127_2373030_161	1397696.KK211189_gene1464	2.404e-20	97.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3WETC@539002|Bacillales incertae sedis	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS2_k127_2373030_38	926569.ANT_14340	4.424e-113	391.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
GDHHQS2_k127_2373030_145	1408423.JHYA01000005_gene1828	9.825e-28	119.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4H4MK@909932|Negativicutes	909932|Negativicutes	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS2_k127_2373030_127	177439.DP0885	1.044e-36	142.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2MPV7@213118|Desulfobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS2_k127_2373030_35	926569.ANT_16230	9.008e-119	396.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
GDHHQS2_k127_2373030_180	765420.OSCT_1064	9.831e-10	69.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS2_k127_2373030_188	1215343.B488_00700	5.199e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,4B8TR@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	FOG TPR repeat	MA20_42300	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS2_k127_2373030_175	877420.ATVW01000023_gene114	1.099e-11	70.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,27ITP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2373030_159	1463853.JOHW01000014_gene293	3.289e-21	105.0	COG2227@1|root,COG2227@2|Bacteria,2GNRH@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS2_k127_2373030_64	1449126.JQKL01000011_gene3577	3.736e-80	278.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7
GDHHQS2_k127_2373030_99	1128421.JAGA01000003_gene2899	7.002e-52	193.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS2_k127_2373030_167	635013.TherJR_0243	1.085e-15	90.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS2_k127_2373030_105	1121946.AUAX01000001_gene2353	1.08e-46	186.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria,4D8XB@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_2373030_50	926550.CLDAP_22380	5.473e-94	315.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2373030_207	69395.JQLZ01000002_gene1317	0.0005787	45.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U3DK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2373030_133	439235.Dalk_3383	1.055e-33	136.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,43CS4@68525|delta/epsilon subdivisions,2X7ZT@28221|Deltaproteobacteria,2MND2@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	2.7.7.58,6.3.2.14	ko:K02363,ko:K04116	ko00362,ko01053,ko01110,ko01120,ko01130,map00362,map01053,map01110,map01120,map01130	M00540	R05620,R07644	RC00004,RC00162,RC01438,RC03046	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2373030_193	1174684.EBMC1_02340	1.204e-06	51.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U3DK@28211|Alphaproteobacteria,2K2RK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2373030_117	118166.JH976537_gene578	6.711e-39	162.0	COG1262@1|root,COG2815@1|root,COG1262@2|Bacteria,COG2815@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_2373030_9	926569.ANT_10620	3.158e-210	683.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
GDHHQS2_k127_2373030_199	525904.Tter_2106	2.544e-05	57.0	COG0308@1|root,COG3103@1|root,COG0308@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.4.11.2,3.4.21.96	ko:K01256,ko:K01361	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_MA_2,SH3_3,SpoIID
GDHHQS2_k127_2373030_177	1210046.B277_02681	3.497e-11	67.0	COG3339@1|root,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria,4FJD6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_52	926569.ANT_25070	3.396e-92	315.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GDHHQS2_k127_2373030_149	926569.ANT_25060	6.227e-25	111.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS2_k127_2373030_2	926569.ANT_25050	7.871e-283	882.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS2_k127_2373030_29	926569.ANT_25040	3.174e-125	412.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_2373030_78	926569.ANT_25030	1.066e-66	239.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS2_k127_2373030_183	545693.BMQ_4836	1.725e-08	66.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS2_k127_2373030_143	926569.ANT_28280	6.713e-30	120.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS2_k127_2373030_166	926569.ANT_28270	1.066e-15	78.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS2_k127_2373030_49	1128421.JAGA01000002_gene455	2.425e-94	322.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_2373030_200	1340434.AXVA01000005_gene4673	4.063e-05	57.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
GDHHQS2_k127_2373030_146	1121422.AUMW01000024_gene240	1.125e-27	121.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2373030_21	383372.Rcas_2157	1.907e-134	436.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,3766S@32061|Chloroflexia	32061|Chloroflexia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS2_k127_2373030_93	926569.ANT_01450	2.413e-56	202.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GDHHQS2_k127_2373030_47	1128421.JAGA01000002_gene455	2.946e-99	339.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_2373030_173	411477.PARMER_03989	8.029e-12	76.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,2FP5X@200643|Bacteroidia,22WQ4@171551|Porphyromonadaceae	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS2_k127_2373030_18	1005048.CFU_3993	3.129e-152	511.0	COG0318@1|root,COG2267@1|root,COG0318@2|Bacteria,COG2267@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS2_k127_2373030_67	926569.ANT_14310	1.598e-78	271.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS2_k127_2373030_205	324602.Caur_1323	0.0003037	48.0	COG1917@1|root,COG1917@2|Bacteria,2G9GF@200795|Chloroflexi,377M6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_2373030_186	523850.TON_1819	3.459e-07	64.0	COG4745@1|root,arCOG00562@2157|Archaea,2Y6NZ@28890|Euryarchaeota,244ZB@183968|Thermococci	183968|Thermococci	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2373030_113	1128421.JAGA01000002_gene78	6.179e-42	177.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
GDHHQS2_k127_2373030_46	1205753.A989_03761	1.907e-100	344.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria,1X5SI@135614|Xanthomonadales	135614|Xanthomonadales	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_2373030_33	204669.Acid345_2810	1.996e-121	401.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS2_k127_2373030_109	1395587.P364_0120865	7.79e-43	162.0	COG0251@1|root,COG0251@2|Bacteria,1V7PS@1239|Firmicutes,4HJ6X@91061|Bacilli,26XRY@186822|Paenibacillaceae	91061|Bacilli	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_2373030_108	1382306.JNIM01000001_gene1580	1.354e-44	170.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_2373030_191	65497.JODV01000002_gene4207	1.046e-06	59.0	COG1266@1|root,COG1266@2|Bacteria,2IFZI@201174|Actinobacteria,4E2RE@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_2373030_10	926569.ANT_05220	6.007e-203	647.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS2_k127_2373030_190	118168.MC7420_5696	8.465e-07	58.0	COG1716@1|root,COG1716@2|Bacteria,1G5ZN@1117|Cyanobacteria,1HFKR@1150|Oscillatoriales	1117|Cyanobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_2373030_138	1121875.KB907547_gene3443	6.841e-32	128.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
GDHHQS2_k127_2373030_60	388413.ALPR1_05140	3.755e-85	291.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS2_k127_2373030_74	765420.OSCT_0396	2.655e-70	246.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS2_k127_2373030_43	926550.CLDAP_13110	4.227e-104	347.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2373030_62	926550.CLDAP_15380	5.139e-81	277.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_2373030_89	926569.ANT_01000	1.459e-58	211.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS2_k127_2373030_32	926550.CLDAP_39140	8.224e-124	406.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_2373030_137	926550.CLDAP_39150	4.393e-32	134.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
GDHHQS2_k127_2373030_172	765420.OSCT_1611	7.195e-12	74.0	COG3944@1|root,COG3944@2|Bacteria,2G9GX@200795|Chloroflexi,375NI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
GDHHQS2_k127_2373030_79	383372.Rcas_3668	1.297e-66	234.0	COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,ParA
GDHHQS2_k127_2373030_162	1313172.YM304_39900	1.496e-19	101.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria	201174|Actinobacteria	S	Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_2373030_17	926550.CLDAP_01250	8.601e-163	518.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_2373030_4	880073.Calab_1860	4.759e-227	723.0	COG2183@1|root,COG2183@2|Bacteria,2NP2S@2323|unclassified Bacteria	2|Bacteria	K	Tex-like protein N-terminal domain	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GDHHQS2_k127_2373030_150	1242864.D187_000804	1.994e-24	116.0	COG1388@1|root,COG1652@1|root,COG3409@1|root,COG1388@2|Bacteria,COG1652@2|Bacteria,COG3409@2|Bacteria,1PG5E@1224|Proteobacteria,434XM@68525|delta/epsilon subdivisions,2X92K@28221|Deltaproteobacteria,2Z1JU@29|Myxococcales	28221|Deltaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_46,LysM,PG_binding_1
GDHHQS2_k127_2373030_118	926569.ANT_02430	9.804e-39	154.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_28	926569.ANT_00500	9.778e-128	422.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
GDHHQS2_k127_2373030_25	1128421.JAGA01000003_gene2998	1.285e-129	422.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
GDHHQS2_k127_2373030_112	316274.Haur_3496	2.067e-42	176.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi,37581@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_2373030_178	1444309.JAQG01000177_gene4391	7.863e-11	73.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,274AD@186822|Paenibacillaceae	91061|Bacilli	G	Polysaccharide deacetylase	cda1	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,Polysacc_deac_1
GDHHQS2_k127_2373030_182	861299.J421_0242	1.327e-08	67.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_2373030_141	1382356.JQMP01000003_gene1423	4.319e-31	139.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_2373030_125	368407.Memar_1531	8.588e-37	157.0	COG5635@1|root,arCOG04006@1|root,arCOG02967@2157|Archaea,arCOG04006@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
GDHHQS2_k127_2373030_156	309801.trd_1490	6.194e-23	101.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_2373030_98	765420.OSCT_2550	2.942e-52	193.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2373030_116	357808.RoseRS_3026	2.074e-39	168.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_2373030_81	546271.Selsp_0850	2.628e-63	228.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS2_k127_2373030_86	1128421.JAGA01000003_gene3421	3.419e-60	217.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS2_k127_2373030_195	1121324.CLIT_23c02830	4.514e-06	51.0	COG0762@1|root,COG0762@2|Bacteria,1TV4X@1239|Firmicutes,259HI@186801|Clostridia,25UA2@186804|Peptostreptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS2_k127_2373030_160	926569.ANT_18430	1.16e-20	98.0	COG1872@1|root,COG1872@2|Bacteria,2G7H4@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS2_k127_2373030_155	525904.Tter_1271	5.608e-23	108.0	2DRD4@1|root,33B9X@2|Bacteria,2NRTN@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_87	926569.ANT_18420	1.732e-59	233.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
GDHHQS2_k127_2373030_174	748449.Halha_1866	1.028e-11	74.0	COG1579@1|root,COG1579@2|Bacteria,1VHZH@1239|Firmicutes,24TIU@186801|Clostridia	186801|Clostridia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS2_k127_2373030_104	926569.ANT_18400	3.648e-48	193.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_84	926569.ANT_18380	1.709e-62	236.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_30	926569.ANT_18370	1.009e-124	428.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS2_k127_2373030_40	357808.RoseRS_0402	1.037e-107	366.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi,377XR@32061|Chloroflexia	32061|Chloroflexia	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS2_k127_2373030_158	926569.ANT_28840	3.115e-22	113.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K02849,ko:K21003	ko00540,ko01100,ko02025,map00540,map01100,map02025	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	9.B.67.4,9.B.67.5	GT9	-	Glyco_transf_25,Wzy_C
GDHHQS2_k127_2373030_69	926550.CLDAP_23270	3.723e-77	266.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_2373030_36	926569.ANT_11490	6.995e-114	385.0	COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_73	926569.ANT_26880	2.27e-70	260.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2373030_91	926569.ANT_11570	5.759e-57	224.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GDHHQS2_k127_2373030_204	383372.Rcas_1941	0.0001261	55.0	COG1807@1|root,COG1807@2|Bacteria,2GAAY@200795|Chloroflexi,374TV@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2373030_59	926569.ANT_11560	3.667e-85	301.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2373030_83	309801.trd_1669	3.639e-63	224.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2373030_76	926569.ANT_11580	3.973e-69	248.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
GDHHQS2_k127_2373030_12	316274.Haur_1692	1.11e-191	614.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376IG@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3,6.2.1.48	ko:K01897,ko:K02182,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_2381819_48	391612.CY0110_01265	1.214e-06	55.0	COG3655@1|root,COG3655@2|Bacteria,1GAW8@1117|Cyanobacteria	1117|Cyanobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
GDHHQS2_k127_2381819_53	112098.XP_008610809.1	0.0002168	53.0	KOG0583@1|root,KOG0583@2759|Eukaryota	2759|Eukaryota	G	protein serine/threonine kinase activity	-	-	2.7.11.11	ko:K07198	ko04068,ko04140,ko04150,ko04151,ko04152,ko04211,ko04213,ko04371,ko04530,ko04710,ko04714,ko04910,ko04920,ko04921,ko04922,ko04931,ko04932,ko05410,ko05418,map04068,map04140,map04150,map04151,map04152,map04211,map04213,map04371,map04530,map04710,map04714,map04910,map04920,map04921,map04922,map04931,map04932,map05410,map05418	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03029,ko04131	-	-	-	NAF,Pkinase
GDHHQS2_k127_2381819_25	285535.JOEY01000008_gene8746	8.003e-37	142.0	2DNXR@1|root,32ZPP@2|Bacteria,2I2KW@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
GDHHQS2_k127_2381819_20	1304880.JAGB01000002_gene2048	2.597e-49	195.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_2381819_13	946235.CAER01000026_gene920	4.685e-64	227.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,23ITH@182709|Oceanobacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2381819_12	357808.RoseRS_0609	1.087e-65	237.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,375JB@32061|Chloroflexia	32061|Chloroflexia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS2_k127_2381819_28	1123034.JMKP01000011_gene555	3.195e-27	120.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS2_k127_2381819_16	410358.Mlab_1692	4.71e-57	206.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
GDHHQS2_k127_2381819_4	1121090.KB894698_gene4244	6.275e-127	413.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1ZBD0@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS2_k127_2381819_22	84531.JMTZ01000033_gene260	1.24e-42	168.0	2C5JX@1|root,32WNU@2|Bacteria,1NUC9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_35	926569.ANT_06190	1.354e-16	83.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
GDHHQS2_k127_2381819_32	935863.AWZR01000001_gene1586	3.485e-22	100.0	COG0642@1|root,COG2205@2|Bacteria,1N96D@1224|Proteobacteria,1RPN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2381819_42	1123073.KB899242_gene1316	5.772e-10	69.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_2381819_34	1521187.JPIM01000042_gene1850	9.851e-19	94.0	2FFVE@1|root,347SF@2|Bacteria,2GB3K@200795|Chloroflexi,377UV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_29	449447.MAE_46050	5.552e-26	111.0	COG0517@1|root,COG0517@2|Bacteria,1G08K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
GDHHQS2_k127_2381819_36	1121104.AQXH01000001_gene1722	2.886e-14	77.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,4NFNF@976|Bacteroidetes	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
GDHHQS2_k127_2381819_7	926569.ANT_26230	1.817e-102	346.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS2_k127_2381819_56	479435.Kfla_3917	0.0008162	53.0	COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria,4DSI4@85009|Propionibacteriales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_2381819_30	349161.Dred_2286	2.084e-25	114.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2381819_31	1111454.HMPREF1250_0582	1.892e-24	111.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,4H57R@909932|Negativicutes	909932|Negativicutes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_43	159749.K0SRF8	6.603e-09	67.0	COG2335@1|root,KOG1437@2759|Eukaryota,2XG8M@2836|Bacillariophyta	2836|Bacillariophyta	MW	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
GDHHQS2_k127_2381819_44	1082705.JIBP01000003_gene2326	5.602e-08	57.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS2_k127_2381819_23	926569.ANT_26250	2.287e-38	148.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
GDHHQS2_k127_2381819_37	1232683.ADIMK_3831	2.529e-13	74.0	COG1366@1|root,COG1366@2|Bacteria,1NECY@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
GDHHQS2_k127_2381819_14	1487953.JMKF01000008_gene6013	6.031e-63	231.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1H9A9@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS2_k127_2381819_8	1191523.MROS_0749	4.704e-92	317.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS2_k127_2381819_3	479434.Sthe_1490	1.022e-153	503.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS2_k127_2381819_1	404589.Anae109_2250	1.686e-193	623.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GDHHQS2_k127_2381819_46	1089553.Tph_c04540	3.95e-07	62.0	COG1918@1|root,COG1918@2|Bacteria,1VMJD@1239|Firmicutes,24VI7@186801|Clostridia,42HGN@68295|Thermoanaerobacterales	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
GDHHQS2_k127_2381819_9	511051.CSE_03870	1.882e-91	314.0	COG3833@1|root,COG3833@2|Bacteria	2|Bacteria	P	maltose-transporting ATPase activity	malG	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GDHHQS2_k127_2381819_6	511051.CSE_03860	1.079e-107	358.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	malF	-	-	ko:K02025,ko:K15770,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,SBP_bac_8
GDHHQS2_k127_2381819_17	511051.CSE_03850	6.587e-57	214.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K15770,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,Cu_amine_oxidN1,SBP_bac_8
GDHHQS2_k127_2381819_15	1122182.KB903837_gene3780	1.507e-59	218.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_2381819_27	317936.Nos7107_4124	9.05e-31	128.0	COG1943@1|root,COG1943@2|Bacteria,1G6SS@1117|Cyanobacteria,1HNZ8@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS2_k127_2381819_2	926569.ANT_25010	4.014e-191	609.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
GDHHQS2_k127_2381819_11	1047013.AQSP01000131_gene1797	9.463e-70	248.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_2381819_0	1121405.dsmv_2307	1.173e-210	665.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
GDHHQS2_k127_2381819_54	1410620.SHLA_88c000080	0.0007044	46.0	COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,2UF77@28211|Alphaproteobacteria,4BM0G@82115|Rhizobiaceae	28211|Alphaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_2381819_45	1434325.AZQN01000010_gene3965	6.369e-08	65.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS2_k127_2381819_19	324602.Caur_0192	9.676e-56	220.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4
GDHHQS2_k127_2381819_51	1249627.D779_3099	8.059e-05	54.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1RNS3@1236|Gammaproteobacteria,1WY2Y@135613|Chromatiales	135613|Chromatiales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS2_k127_2381819_26	1217703.F904_03795	1.768e-35	142.0	2E4GH@1|root,32ZBP@2|Bacteria,1NDRK@1224|Proteobacteria,1SDX6@1236|Gammaproteobacteria,3NNKK@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_47	1120936.KB907212_gene5161	5.909e-07	54.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4EJE1@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_2381819_21	926569.ANT_18400	4.547e-43	178.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_10	485913.Krac_3297	2.791e-88	297.0	COG1028@1|root,COG1028@2|Bacteria,2G85A@200795|Chloroflexi	200795|Chloroflexi	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_2381819_5	926560.KE387023_gene2479	1.26e-124	411.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS2_k127_2381819_18	357808.RoseRS_0204	2.504e-56	215.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_2381819_38	1521187.JPIM01000103_gene1036	5.767e-12	72.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2381819_41	1223521.BBJX01000007_gene1436	1.942e-10	68.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,2WGTG@28216|Betaproteobacteria,4AIN6@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_2381819_39	298655.KI912266_gene3034	9.641e-12	70.0	COG0745@1|root,COG0745@2|Bacteria,2I2VM@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GDHHQS2_k127_2381819_24	1499967.BAYZ01000123_gene2505	1.437e-37	145.0	2E3GF@1|root,32YF7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2381819_40	712898.Pvag_2206	1.179e-11	76.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,3VZ1B@53335|Pantoea	1236|Gammaproteobacteria	T	Histidine kinase	cpxA_1	-	2.7.13.3	ko:K02484,ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HK_sensor,HisKA
GDHHQS2_k127_2381819_49	530564.Psta_4097	1.514e-06	58.0	COG0642@1|root,COG2205@2|Bacteria,2IYBD@203682|Planctomycetes	203682|Planctomycetes	T	Osmosensitive K channel His kinase sensor	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
GDHHQS2_k127_2456494_18	485913.Krac_12496	2.186e-49	181.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS2_k127_2456494_4	926569.ANT_25910	1.874e-119	404.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS2_k127_2456494_36	1907.SGLAU_31420	7.839e-08	65.0	COG2340@1|root,COG2340@2|Bacteria,2I39U@201174|Actinobacteria	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GDHHQS2_k127_2456494_39	765420.OSCT_1771	9.504e-05	53.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
GDHHQS2_k127_2456494_26	1173028.ANKO01000009_gene1699	4.227e-24	115.0	COG3021@1|root,COG3021@2|Bacteria,1G9UD@1117|Cyanobacteria,1HF39@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS2_k127_2456494_6	1195236.CTER_3382	2.412e-114	413.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,3WGBY@541000|Ruminococcaceae	186801|Clostridia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_2456494_3	1121377.KB906405_gene101	2.731e-121	401.0	COG0208@1|root,COG0208@2|Bacteria,1WM54@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	fatty acid desaturase	staD	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
GDHHQS2_k127_2456494_21	1403819.BATR01000191_gene6582	1.306e-41	157.0	COG2867@1|root,COG2867@2|Bacteria,46WZY@74201|Verrucomicrobia,2IW55@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_2456494_32	45351.EDO47632	1.637e-15	91.0	KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa	33208|Metazoa	S	ubiquitin binding	C6orf106	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,UBA_4
GDHHQS2_k127_2456494_16	926550.CLDAP_34880	4.795e-62	237.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
GDHHQS2_k127_2456494_0	945713.IALB_2868	1.549e-247	772.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GDHHQS2_k127_2456494_14	485913.Krac_0962	2.998e-73	267.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GDHHQS2_k127_2456494_15	485913.Krac_0962	6.982e-68	251.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GDHHQS2_k127_2456494_38	702113.PP1Y_AT4105	6.559e-06	58.0	COG2367@1|root,COG2367@2|Bacteria,1PNSR@1224|Proteobacteria,2U483@28211|Alphaproteobacteria,2K1SY@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
GDHHQS2_k127_2456494_33	1286171.EAL2_c03300	1.533e-14	85.0	COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes	1239|Firmicutes	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GDHHQS2_k127_2456494_40	118173.KB235914_gene2969	0.0008299	52.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
GDHHQS2_k127_2456494_34	7159.AAEL014195-PA	5.681e-10	72.0	KOG1130@1|root,KOG1130@2759|Eukaryota,38BEC@33154|Opisthokonta,3BBV7@33208|Metazoa,3CSNR@33213|Bilateria,41TFF@6656|Arthropoda,3SGJQ@50557|Insecta,4504Z@7147|Diptera,45GKZ@7148|Nematocera	33208|Metazoa	T	G-protein signalling modulator	GPSM2	GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0000922,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007163,GO:0007165,GO:0007186,GO:0007264,GO:0007265,GO:0007275,GO:0007346,GO:0007399,GO:0007400,GO:0007405,GO:0008022,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010564,GO:0010638,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0015630,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0023052,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031291,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0034260,GO:0035556,GO:0036445,GO:0040001,GO:0042175,GO:0042802,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043547,GO:0043621,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044877,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0045787,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0050896,GO:0051098,GO:0051099,GO:0051100,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051642,GO:0051649,GO:0051651,GO:0051653,GO:0051656,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0055057,GO:0055059,GO:0060236,GO:0060259,GO:0060341,GO:0060589,GO:0061351,GO:0061842,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070507,GO:0070840,GO:0071840,GO:0071944,GO:0072089,GO:0072686,GO:0090068,GO:0090169,GO:0090224,GO:0097431,GO:0097574,GO:0097575,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902115,GO:1902117,GO:1902850,GO:1903047,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904424,GO:1904776,GO:1904778,GO:1905097,GO:1905098,GO:1905832	-	ko:K15837,ko:K15839	ko05030,map05030	-	-	-	ko00000,ko00001,ko03036	-	-	-	GoLoco,TPR_12,TPR_7,TPR_8
GDHHQS2_k127_2456494_25	292459.STH932	6.273e-29	116.0	COG1942@1|root,COG1942@2|Bacteria,1VGNJ@1239|Firmicutes,24QU3@186801|Clostridia	186801|Clostridia	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
GDHHQS2_k127_2456494_23	926560.KE387023_gene2058	5.898e-35	139.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_2456494_1	472759.Nhal_3185	8.613e-219	697.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,1X0CY@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_2456494_22	388467.A19Y_1582	1.815e-38	154.0	2DDH6@1|root,2ZI31@2|Bacteria,1G5G0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
GDHHQS2_k127_2456494_30	1242864.D187_002628	6.304e-17	86.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_2456494_27	161156.JQKW01000007_gene687	2.46e-22	101.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2GIQF@200940|Thermodesulfobacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_2456494_17	1288298.rosmuc_02975	6.477e-56	216.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2V6JN@28211|Alphaproteobacteria,46QKC@74030|Roseovarius	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2456494_29	335543.Sfum_2208	3.192e-17	87.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_2456494_31	1123073.KB899242_gene1480	8.013e-17	89.0	COG2197@1|root,COG2197@2|Bacteria,1RAQG@1224|Proteobacteria,1S31E@1236|Gammaproteobacteria,1X4HP@135614|Xanthomonadales	135614|Xanthomonadales	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2456494_8	240292.Ava_C0001	5.086e-91	316.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1HKQS@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_2456494_35	1459636.NTE_02332	2.482e-09	67.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2456494_10	485913.Krac_5497	8.319e-86	294.0	COG0384@1|root,COG0384@2|Bacteria,2G8NU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GDHHQS2_k127_2456494_9	118173.KB235914_gene861	8.241e-86	300.0	COG1881@1|root,COG1881@2|Bacteria,1G1EC@1117|Cyanobacteria	1117|Cyanobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
GDHHQS2_k127_2456494_13	91464.S7335_1645	4.624e-79	276.0	COG0226@1|root,COG0226@2|Bacteria,1FZZ0@1117|Cyanobacteria,1GZ49@1129|Synechococcus	1117|Cyanobacteria	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
GDHHQS2_k127_2456494_7	1196323.ALKF01000192_gene3214	4.385e-103	345.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,26SNZ@186822|Paenibacillaceae	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS2_k127_2456494_11	518766.Rmar_1827	4.075e-83	288.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1FIYE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS2_k127_2456494_5	926550.CLDAP_00810	2.26e-116	381.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS2_k127_2456494_28	362418.IW19_07925	4.308e-22	104.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I2SV@117743|Flavobacteriia,2P0MB@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_2456494_20	309801.trd_1827	1.326e-46	178.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,27XPS@189775|Thermomicrobia	189775|Thermomicrobia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS2_k127_2456494_24	525904.Tter_2870	1.545e-33	139.0	COG0704@1|root,COG0704@2|Bacteria,2NPWX@2323|unclassified Bacteria	2|Bacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS2_k127_2456494_2	1121428.DESHY_70069___1	1.083e-125	420.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
GDHHQS2_k127_2456494_19	1408473.JHXO01000008_gene2655	6.269e-49	187.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_2456494_12	926550.CLDAP_39300	3.167e-81	297.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
GDHHQS2_k127_2456865_10	679926.Mpet_1589	3.405e-51	212.0	COG3209@1|root,arCOG12091@2157|Archaea,2Y87Z@28890|Euryarchaeota,2NBP1@224756|Methanomicrobia	224756|Methanomicrobia	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2456865_17	1907.SGLAU_31890	3.052e-12	83.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GDHHQS2_k127_2456865_6	717606.PaecuDRAFT_2033	4.88e-93	350.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GDHHQS2_k127_2456865_0	626887.J057_06396	0.0	2333.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,465S2@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Cellobiose phosphorylase	ndvB	-	2.4.1.20,2.4.1.280	ko:K00702,ko:K13688,ko:K18675	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00952,R09942	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS2_k127_2456865_13	309801.trd_A0545	4.384e-24	115.0	COG0589@1|root,COG0589@2|Bacteria,2GBUS@200795|Chloroflexi,27Z69@189775|Thermomicrobia	189775|Thermomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_2456865_11	247490.KSU1_C0681	2.502e-32	131.0	COG0662@1|root,COG3339@1|root,COG0662@2|Bacteria,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	XK27_09985	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Cupin_2,DUF1232,tRNA-synt_1g
GDHHQS2_k127_2456865_16	521045.Kole_0436	4.217e-15	83.0	2DUHG@1|root,33QNU@2|Bacteria,2GDRM@200918|Thermotogae	200918|Thermotogae	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GDHHQS2_k127_2456865_3	1499967.BAYZ01000036_gene2415	1.336e-200	635.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS2_k127_2456865_9	1120746.CCNL01000017_gene2422	4.081e-58	211.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_2456865_8	1120746.CCNL01000017_gene2423	4.963e-59	217.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS2_k127_2456865_14	279238.Saro_0697	6.158e-17	86.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria,2K3P4@204457|Sphingomonadales	204457|Sphingomonadales	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS2_k127_2456865_4	264732.Moth_0707	1.44e-119	405.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,42EZ2@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS2_k127_2456865_15	1231377.C426_0568	8.384e-16	89.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,1YB38@1357|Lactococcus	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS2_k127_2456865_5	1521187.JPIM01000024_gene718	3.139e-94	318.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi,376X6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GDHHQS2_k127_2456865_1	518766.Rmar_1549	3.877e-264	831.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	dehydrogenase, E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS2_k127_2456865_2	926550.CLDAP_15280	6.542e-220	710.0	COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi	200795|Chloroflexi	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS2_k127_2456865_7	395961.Cyan7425_3349	8.653e-67	246.0	COG2251@1|root,COG2251@2|Bacteria,1G03D@1117|Cyanobacteria,3KG1W@43988|Cyanothece	1117|Cyanobacteria	S	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,RNase_H_2
GDHHQS2_k127_2456865_12	445961.IW15_21435	6.462e-31	139.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia,3ZNMD@59732|Chryseobacterium	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS2_k127_2463064_0	1242864.D187_001830	4.255e-205	676.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_2463064_9	555088.DealDRAFT_1756	1.149e-89	302.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
GDHHQS2_k127_2463064_13	926550.CLDAP_18750	3.73e-83	284.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
GDHHQS2_k127_2463064_5	926550.CLDAP_18740	4.311e-120	395.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GDHHQS2_k127_2463064_28	485913.Krac_6669	4.683e-49	183.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2463064_29	909663.KI867151_gene3159	1.392e-48	198.0	COG2202@1|root,COG4191@1|root,COG4585@1|root,COG5001@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21084	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,dCache_1
GDHHQS2_k127_2463064_40	402777.KB235898_gene5734	6.146e-07	63.0	COG2203@1|root,COG2905@1|root,COG2203@2|Bacteria,COG2905@2|Bacteria,1GPXH@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GDHHQS2_k127_2463064_25	1304874.JAFY01000007_gene1752	8.192e-54	203.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2463064_1	926569.ANT_27120	1.515e-198	644.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
GDHHQS2_k127_2463064_41	1089548.KI783301_gene1241	4.035e-06	51.0	COG1598@1|root,COG1598@2|Bacteria,1VQEJ@1239|Firmicutes	1239|Firmicutes	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_2463064_39	1123248.KB893315_gene3212	3.656e-09	69.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4PKPQ@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS2_k127_2463064_30	1379698.RBG1_1C00001G1133	1.656e-43	175.0	COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS2_k127_2463064_6	485913.Krac_0576	2.098e-111	369.0	COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS2_k127_2463064_12	926550.CLDAP_24300	1.858e-85	297.0	COG0265@1|root,COG3212@1|root,COG0265@2|Bacteria,COG3212@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS2_k127_2463064_33	504832.OCAR_4266	2.129e-27	121.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,3JVGB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS2_k127_2463064_26	926569.ANT_30130	1.389e-53	201.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_2463064_8	420324.KI912065_gene6637	3.457e-94	320.0	COG2114@1|root,COG2114@2|Bacteria,1R51D@1224|Proteobacteria,2TT6W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS2_k127_2463064_17	290315.Clim_2177	1.004e-61	221.0	COG1028@1|root,COG1028@2|Bacteria,1FF3B@1090|Chlorobi	1090|Chlorobi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463064_11	526225.Gobs_2142	8.362e-88	312.0	COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463064_43	1289387.AUKW01000009_gene4321	7.756e-05	55.0	COG1716@1|root,COG1716@2|Bacteria,2GK5I@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_2463064_22	1128421.JAGA01000003_gene3096	4.499e-57	213.0	COG0803@1|root,COG0803@2|Bacteria,2NP5U@2323|unclassified Bacteria	2|Bacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
GDHHQS2_k127_2463064_3	523841.HFX_2635	5.066e-141	464.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23RWR@183963|Halobacteria	183963|Halobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD2	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_2463064_10	926569.ANT_22510	5.542e-89	300.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2463064_18	525904.Tter_2194	6.196e-61	240.0	COG0745@1|root,COG2197@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K03413,ko:K07684,ko:K07689	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00471,M00475,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GAF,GAF_2,GerE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3
GDHHQS2_k127_2463064_19	1499967.BAYZ01000073_gene2016	5.075e-60	214.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
GDHHQS2_k127_2463064_2	926569.ANT_03160	3.026e-161	526.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS2_k127_2463064_4	649638.Trad_1384	1.437e-132	440.0	COG2041@1|root,COG2041@2|Bacteria,1WI25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GDHHQS2_k127_2463064_36	1089544.KB912942_gene2648	1.174e-15	88.0	COG3212@1|root,COG3212@2|Bacteria,2IF4I@201174|Actinobacteria	201174|Actinobacteria	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463064_42	485913.Krac_12159	7.18e-05	56.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GDHHQS2_k127_2463064_37	264732.Moth_0908	7.533e-12	79.0	COG1716@1|root,COG1716@2|Bacteria,1VF0E@1239|Firmicutes,24P12@186801|Clostridia,42GKE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Forkhead-associated	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_2463064_15	526225.Gobs_2142	7.198e-81	295.0	COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463064_14	765420.OSCT_1920	4.002e-83	285.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	32061|Chloroflexia	P	ABC-3 protein	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
GDHHQS2_k127_2463064_7	1307761.L21SP2_2459	7.091e-98	327.0	COG1121@1|root,COG1121@2|Bacteria,2J6HR@203691|Spirochaetes	203691|Spirochaetes	P	ABC transporter	znuC	-	-	ko:K09817,ko:K11607,ko:K11710	ko02010,map02010	M00242,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
GDHHQS2_k127_2463064_34	497965.Cyan7822_4276	3.403e-23	105.0	COG0147@1|root,COG0801@1|root,COG0147@2|Bacteria,COG0801@2|Bacteria,1G2D4@1117|Cyanobacteria,3KGQC@43988|Cyanothece	1117|Cyanobacteria	EH	Anthranilate synthase component I domain protein	trpE2	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046820,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS2_k127_2463064_32	1237500.ANBA01000014_gene5642	5.554e-30	122.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
GDHHQS2_k127_2463064_21	998088.B565_3208	2.505e-57	211.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
GDHHQS2_k127_2463064_24	1123274.KB899410_gene3439	2.504e-55	203.0	COG1028@1|root,COG1028@2|Bacteria,2JAPN@203691|Spirochaetes	203691|Spirochaetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2463064_20	383372.Rcas_0301	2.019e-59	213.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS2_k127_2463064_16	1121430.JMLG01000010_gene208	4.36e-67	239.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
GDHHQS2_k127_2463064_23	867845.KI911784_gene1719	4.577e-56	207.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
GDHHQS2_k127_2463064_31	479434.Sthe_2391	3.089e-35	141.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_2463064_27	357808.RoseRS_0520	6.052e-50	195.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2GAA9@200795|Chloroflexi,376WV@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_2463241_7	1094980.Mpsy_0389	1.681e-61	231.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2N9HJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_2463241_3	926554.KI912637_gene3278	4.574e-106	349.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
GDHHQS2_k127_2463241_0	926569.ANT_22150	1.694e-250	785.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS2_k127_2463241_12	644966.Tmar_0119	3.093e-18	89.0	COG2142@1|root,COG2142@2|Bacteria,1VP1A@1239|Firmicutes,24XAD@186801|Clostridia	186801|Clostridia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS2_k127_2463241_11	926569.ANT_22170	1.117e-24	108.0	COG2009@1|root,COG2009@2|Bacteria,2G7CW@200795|Chloroflexi	200795|Chloroflexi	C	succinate dehydrogenase, cytochrome	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS2_k127_2463241_10	215803.DB30_1757	4.376e-34	138.0	2ENZC@1|root,33GK8@2|Bacteria,1Q928@1224|Proteobacteria,437HP@68525|delta/epsilon subdivisions,2X2R8@28221|Deltaproteobacteria,2YVM5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463241_6	373903.Hore_16050	5.057e-71	251.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WB29@53433|Halanaerobiales	186801|Clostridia	GK	TIGRFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
GDHHQS2_k127_2463241_9	1173026.Glo7428_4685	1.289e-36	155.0	COG1664@1|root,COG1664@2|Bacteria,1G2TI@1117|Cyanobacteria	1117|Cyanobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS2_k127_2463241_8	1173024.KI912148_gene2781	8.95e-59	209.0	COG4894@1|root,COG4894@2|Bacteria,1G3DI@1117|Cyanobacteria,1JKP7@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2463241_4	357808.RoseRS_2193	8.803e-104	351.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,3757S@32061|Chloroflexia	32061|Chloroflexia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GDHHQS2_k127_2463241_2	326427.Cagg_1406	1.162e-132	437.0	COG2211@1|root,COG2211@2|Bacteria,2G6RZ@200795|Chloroflexi,3764D@32061|Chloroflexia	32061|Chloroflexia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
GDHHQS2_k127_2463241_5	926569.ANT_18240	7.34e-93	311.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS2_k127_2463241_1	926569.ANT_18230	3.02e-212	673.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS2_k127_2509379_28	525904.Tter_0136	2.99e-18	96.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_2509379_11	1340493.JNIF01000003_gene3961	8.244e-68	255.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS2_k127_2509379_14	1071085.KK033114_gene1172	2.615e-58	213.0	arCOG08204@1|root,arCOG08204@2157|Archaea,2XWZG@28890|Euryarchaeota,23VDX@183963|Halobacteria	183963|Halobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
GDHHQS2_k127_2509379_36	1238184.CM001792_gene2715	4.739e-06	52.0	COG0463@1|root,COG3115@1|root,COG0463@2|Bacteria,COG3115@2|Bacteria,1TQEM@1239|Firmicutes,4H9X9@91061|Bacilli,23K37@182709|Oceanobacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
GDHHQS2_k127_2509379_2	316274.Haur_3267	1.57e-168	541.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_2509379_20	383372.Rcas_1702	1.206e-35	142.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_2509379_7	1121272.KB903290_gene4600	3.133e-85	285.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4DIUT@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS2_k127_2509379_24	383372.Rcas_1703	3.268e-24	110.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_2509379_30	1384056.N787_10745	1.106e-15	83.0	2E8TD@1|root,3140Q@2|Bacteria,1QD9G@1224|Proteobacteria,1SSRP@1236|Gammaproteobacteria,1XBS0@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2509379_40	1123073.KB899241_gene3279	0.0003462	53.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1X51Q@135614|Xanthomonadales	135614|Xanthomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_2509379_17	485913.Krac_8856	2.586e-45	169.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	p20	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS2_k127_2509379_1	926569.ANT_00050	4.306e-178	569.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_2509379_0	1121405.dsmv_2629	2.545e-235	739.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MHYG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM malic	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
GDHHQS2_k127_2509379_10	379066.GAU_3677	6.526e-71	244.0	COG4832@1|root,COG4832@2|Bacteria	2|Bacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
GDHHQS2_k127_2509379_19	484770.UFO1_4007	9.313e-38	153.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GDHHQS2_k127_2509379_37	765420.OSCT_1735	6.082e-06	55.0	COG3103@1|root,COG4991@2|Bacteria,2GBHW@200795|Chloroflexi,3761I@32061|Chloroflexia	32061|Chloroflexia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS2_k127_2509379_26	469383.Cwoe_1551	6.282e-22	109.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_2509379_39	13037.EHJ68109	0.0002068	53.0	KOG1217@1|root,KOG3594@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4430M@7088|Lepidoptera	33208|Metazoa	T	Epidermal growth factor-like domain.	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
GDHHQS2_k127_2509379_41	448385.sce4949	0.0006113	52.0	COG0402@1|root,COG1506@1|root,COG5184@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
GDHHQS2_k127_2509379_22	1116472.MGMO_44c00350	6.099e-26	114.0	COG3600@1|root,COG3600@2|Bacteria,1N1VK@1224|Proteobacteria,1S91V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
GDHHQS2_k127_2509379_35	383372.Rcas_1150	3.026e-06	57.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2509379_31	485913.Krac_12282	5.019e-08	63.0	2CHUW@1|root,2ZECY@2|Bacteria,2G9K0@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_2509379_27	1170562.Cal6303_0957	6.275e-19	95.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8,Trypsin_2
GDHHQS2_k127_2509379_4	1265310.CCBD010000058_gene1352	4.397e-102	355.0	COG2114@1|root,COG2114@2|Bacteria,2IEX3@201174|Actinobacteria,23CQN@1762|Mycobacteriaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS2_k127_2509379_32	1510531.JQJJ01000014_gene4817	6.424e-08	62.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2TT8T@28211|Alphaproteobacteria,3JRKQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	MA20_14295	-	1.13.11.37	ko:K04098	ko00361,ko00362,ko01100,ko01120,map00361,map00362,map01100,map01120	-	R03891,R04061	RC00388,RC01016	ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
GDHHQS2_k127_2509379_21	357808.RoseRS_3479	4.311e-26	118.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS2_k127_2509379_5	311424.DhcVS_1445	5.329e-94	319.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2509379_29	1268622.AVS7_04499	3.361e-16	83.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2VTKH@28216|Betaproteobacteria,4AESN@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM death-on-curing family protein	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
GDHHQS2_k127_2509379_9	485913.Krac_3174	2.219e-74	257.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
GDHHQS2_k127_2509379_3	1278073.MYSTI_02057	4.756e-112	384.0	COG0318@1|root,COG3319@1|root,COG0318@2|Bacteria,COG3319@2|Bacteria,1MU6G@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,KR,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
GDHHQS2_k127_2509379_38	404589.Anae109_1246	1.259e-05	51.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2Z2NF@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS2_k127_2509379_8	1142394.PSMK_00690	8.603e-82	289.0	COG1696@1|root,COG1696@2|Bacteria,2IX06@203682|Planctomycetes	203682|Planctomycetes	M	membrane protein involved in D-alanine	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
GDHHQS2_k127_2509379_6	926569.ANT_30540	2.101e-91	316.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2509379_33	285535.JOEY01000004_gene10255	1.692e-06	58.0	2CIKF@1|root,3443H@2|Bacteria,2INHT@201174|Actinobacteria	201174|Actinobacteria	S	SUKH-3 immunity protein	-	-	-	-	-	-	-	-	-	-	-	-	SUKH-3
GDHHQS2_k127_2509379_16	926569.ANT_02430	1.573e-46	177.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2509379_25	5888.CAK57909	1.846e-22	113.0	COG0457@1|root,COG3914@1|root,KOG0548@2759|Eukaryota,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	2.1.1.43	ko:K09527,ko:K12600,ko:K19199	ko00310,ko03018,map00310,map03018	M00392	R03875,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000,ko03019,ko03036,ko03110	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS2_k127_2509379_18	373994.Riv7116_4517	3.565e-40	160.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc
GDHHQS2_k127_2509379_12	1089549.AZUQ01000001_gene1417	2.322e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4EY12@85014|Glycomycetales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2509379_15	526227.Mesil_1067	1.812e-52	204.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1WM1I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_2509379_13	272134.KB731324_gene2230	9.891e-59	209.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS2_k127_2527148_12	357808.RoseRS_2229	7.781e-77	268.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_2527148_4	63737.Npun_F6039	1.05e-117	391.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc,TIR_2
GDHHQS2_k127_2527148_39	140110.NechaP34811	6.007e-06	59.0	COG0823@1|root,2QPTW@2759|Eukaryota,38RVS@33154|Opisthokonta,3NZ8B@4751|Fungi,3QSE5@4890|Ascomycota,218QP@147550|Sordariomycetes	4751|Fungi	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_2527148_20	1125863.JAFN01000001_gene2322	5.612e-43	161.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS2_k127_2527148_18	926569.ANT_25530	6.736e-51	189.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS2_k127_2527148_17	926569.ANT_29310	2.422e-51	194.0	299R9@1|root,2ZWTI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2527148_37	42256.RradSPS_0565	9.741e-09	66.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_2527148_10	1128421.JAGA01000003_gene3188	1.162e-88	305.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	-	-	-	ko:K03324,ko:K03466	-	-	-	-	ko00000,ko02000,ko03036	2.A.58.2,3.A.12	-	-	Na_Pi_cotrans,PHO4,PhoU
GDHHQS2_k127_2527148_19	926550.CLDAP_07780	8.551e-50	184.0	COG1418@1|root,COG1418@2|Bacteria,2G77Y@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
GDHHQS2_k127_2527148_25	926550.CLDAP_35190	2.16e-30	123.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2527148_8	926569.ANT_02800	6.903e-91	310.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GDHHQS2_k127_2527148_23	1499967.BAYZ01000013_gene6454	9.117e-36	141.0	COG1186@1|root,COG1186@2|Bacteria,2NRRV@2323|unclassified Bacteria	2|Bacteria	J	RF-1 domain	yaeJ	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GDHHQS2_k127_2527148_35	1304872.JAGC01000003_gene3836	2.63e-09	64.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,42W97@68525|delta/epsilon subdivisions,2WS2D@28221|Deltaproteobacteria,2MCB2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_2527148_33	1173022.Cri9333_0640	3.789e-13	74.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,DUF2963,MORN_2
GDHHQS2_k127_2527148_7	1408418.JNJH01000021_gene1577	1.458e-92	317.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_2527148_36	472759.Nhal_4032	9.479e-09	62.0	2C8P3@1|root,2ZF4A@2|Bacteria,1P4FK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2527148_34	326427.Cagg_3261	5.109e-10	70.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2527148_5	1304874.JAFY01000002_gene895	7.525e-95	323.0	COG0624@1|root,COG0624@2|Bacteria,3TBDJ@508458|Synergistetes	508458|Synergistetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_2527148_21	383372.Rcas_1335	6.073e-40	156.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_2527148_26	317619.ANKN01000034_gene2499	3.794e-28	118.0	COG2402@1|root,COG2402@2|Bacteria,1G7CA@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_2527148_11	443598.AUFA01000028_gene7138	8.776e-83	276.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS2_k127_2527148_0	338969.Rfer_0358	5.209e-148	480.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2527148_15	357808.RoseRS_3553	3.97e-58	209.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_2527148_14	926550.CLDAP_19760	2.983e-64	231.0	COG0646@1|root,COG0646@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
GDHHQS2_k127_2527148_27	756067.MicvaDRAFT_5260	5.119e-27	115.0	COG4113@1|root,COG4113@2|Bacteria,1G6X3@1117|Cyanobacteria,1HDID@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_2527148_1	867845.KI911784_gene1315	1.802e-137	448.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_2527148_24	497965.Cyan7822_3223	1.87e-32	131.0	COG4113@1|root,COG4113@2|Bacteria,1G6PI@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG4113 nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_2527148_44	218284.CCDN010000001_gene1750	0.0002223	43.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus	91061|Bacilli	E	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine	yitJ	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS2_k127_2527148_31	272134.KB731324_gene4128	3.777e-16	85.0	2EHAW@1|root,33B2R@2|Bacteria,1GFD3@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2527148_22	247490.KSU1_B0346	1.183e-39	156.0	COG1028@1|root,COG1028@2|Bacteria,2IZBD@203682|Planctomycetes	203682|Planctomycetes	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_2527148_38	697284.ERIC2_c05920	2.064e-06	51.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26RRM@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_2527148_28	290402.Cbei_4385	6.787e-27	115.0	COG5263@1|root,COG5263@2|Bacteria,1UV66@1239|Firmicutes,24FRI@186801|Clostridia,36I46@31979|Clostridiaceae	186801|Clostridia	E	cell wall binding	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
GDHHQS2_k127_2527148_3	1280380.KR100_01835	3.148e-118	394.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1GZS9@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS2_k127_2527148_2	1380394.JADL01000012_gene843	6.884e-135	437.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2JW6K@204441|Rhodospirillales	204441|Rhodospirillales	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS2_k127_2527148_29	1521187.JPIM01000006_gene1765	1.013e-21	101.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
GDHHQS2_k127_2527148_13	1121324.CLIT_2c03230	1.046e-74	258.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
GDHHQS2_k127_2527148_16	296591.Bpro_0708	1.336e-52	213.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1PF0H@1224|Proteobacteria,2W8ZC@28216|Betaproteobacteria,4AI7H@80864|Comamonadaceae	28216|Betaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,MASE1
GDHHQS2_k127_2527148_9	118168.MC7420_1035	2.124e-90	331.0	COG0642@1|root,COG2202@1|root,COG3605@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_2527148_32	32057.KB217478_gene5704	1.791e-13	78.0	COG0745@1|root,COG0745@2|Bacteria,1G027@1117|Cyanobacteria,1HRVS@1161|Nostocales	1117|Cyanobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
GDHHQS2_k127_2527148_6	926569.ANT_04390	1.541e-94	324.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS2_k127_2556602_4	926550.CLDAP_09880	1.663e-180	591.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS2_k127_2556602_0	1382304.JNIL01000001_gene3056	0.0	1238.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,2793N@186823|Alicyclobacillaceae	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
GDHHQS2_k127_2556602_14	1120950.KB892753_gene6100	8.491e-06	57.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_39
GDHHQS2_k127_2556602_12	251229.Chro_0886	3.149e-30	124.0	COG2337@1|root,COG2337@2|Bacteria,1G7SY@1117|Cyanobacteria,3VNMG@52604|Pleurocapsales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_2556602_6	324602.Caur_3056	1.102e-147	478.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2556602_15	1206741.BAFX01000102_gene1437	0.0001078	53.0	COG1309@1|root,COG1309@2|Bacteria,2IMF7@201174|Actinobacteria,4FTZX@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_2556602_1	313624.NSP_30110	0.0	1137.0	COG3587@1|root,COG3587@2|Bacteria	2|Bacteria	L	Type III restriction enzyme, res subunit	res	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
GDHHQS2_k127_2556602_3	313624.NSP_30120	1.283e-181	588.0	COG2189@1|root,COG2189@2|Bacteria,1GMMQ@1117|Cyanobacteria,1HQTD@1161|Nostocales	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS2_k127_2556602_2	311424.DhcVS_979	1.663e-197	640.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS2_k127_2556602_7	1128421.JAGA01000002_gene1392	1.526e-83	293.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
GDHHQS2_k127_2556602_8	909663.KI867150_gene1732	8.978e-74	259.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,2MRXC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GDHHQS2_k127_2556602_9	118173.KB235914_gene2582	3.646e-73	252.0	COG0110@1|root,COG0110@2|Bacteria,1G8Q2@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
GDHHQS2_k127_2556602_5	269799.Gmet_2332	9.508e-172	547.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_2556602_10	1122222.AXWR01000001_gene1872	4.139e-68	249.0	COG0457@1|root,COG0457@2|Bacteria,1WKXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_2,TPR_8
GDHHQS2_k127_2556602_11	926569.ANT_15160	1.501e-64	230.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GDHHQS2_k127_2556602_13	608538.HTH_0133	3.646e-26	117.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	tehB	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,TehB
GDHHQS2_k127_2556602_16	443218.AS9A_2052	0.0008741	42.0	COG0596@1|root,COG0596@2|Bacteria,2IACG@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_2567435_27	926569.ANT_11840	1.046e-17	89.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_2567435_30	760117.JN27_15860	7.055e-12	71.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VU99@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_2567435_28	316274.Haur_2144	1.057e-16	85.0	COG0784@1|root,COG0784@2|Bacteria,2GB7B@200795|Chloroflexi,377HM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_2567435_14	357808.RoseRS_0204	1.901e-65	244.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_2567435_22	926569.ANT_21000	4.078e-29	117.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GDHHQS2_k127_2567435_15	103733.JNYO01000019_gene2107	1.392e-55	202.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DZ76@85010|Pseudonocardiales	201174|Actinobacteria	T	Member of the two-component regulatory system kdpD kdpE involved in the regulation of the kdp operon	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_2567435_26	525904.Tter_1494	7.769e-19	90.0	COG0745@1|root,COG0745@2|Bacteria	525904.Tter_1494|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2567435_13	926560.KE387023_gene2406	3.262e-72	268.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1WM5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS2_k127_2567435_16	1380391.JIAS01000015_gene78	1.292e-47	177.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria,2U953@28211|Alphaproteobacteria,2JUWV@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS2_k127_2567435_19	247156.NFA_32130	4.88e-38	147.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4G0M5@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
GDHHQS2_k127_2567435_18	1206741.BAFX01000074_gene4410	2.171e-43	161.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4G0GD@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_2567435_3	469383.Cwoe_3437	2.139e-131	425.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
GDHHQS2_k127_2567435_34	383372.Rcas_2161	2.808e-05	55.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_2567435_21	1382306.JNIM01000001_gene448	6.193e-34	143.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PP2C
GDHHQS2_k127_2567435_7	1041147.AUFB01000010_gene1294	1.463e-106	364.0	COG2114@1|root,COG2114@2|Bacteria,1R51D@1224|Proteobacteria,2TT6W@28211|Alphaproteobacteria,4BBKC@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS2_k127_2567435_10	926569.ANT_08960	8.911e-92	315.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G8NY@200795|Chloroflexi	200795|Chloroflexi	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
GDHHQS2_k127_2567435_12	1229520.ADIAL_1416	8.974e-73	262.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,27G37@186828|Carnobacteriaceae	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
GDHHQS2_k127_2567435_9	33035.JPJF01000004_gene2013	9.148e-103	350.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS2_k127_2567435_32	1462526.BN990_00614	4.313e-11	68.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,4C6VV@84406|Virgibacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	licB	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
GDHHQS2_k127_2567435_33	1243664.CAVL020000036_gene2692	2.113e-08	62.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,1ZQH1@1386|Bacillus	91061|Bacilli	G	transporter subunit IIB	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
GDHHQS2_k127_2567435_17	1192034.CAP_4074	2.011e-44	171.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
GDHHQS2_k127_2567435_24	1127695.HMPREF9163_00770	1.135e-22	106.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4H4QY@909932|Negativicutes	909932|Negativicutes	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
GDHHQS2_k127_2567435_29	221109.22777960	1.657e-16	84.0	COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,23KX4@182709|Oceanobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIA subunit	celC	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
GDHHQS2_k127_2567435_4	324057.Pjdr2_0850	6.736e-127	421.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,26QIP@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate	-	-	3.2.1.122,3.2.1.86	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	-	R00837,R00838,R00839,R05133,R05134,R06113	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GH4,GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS2_k127_2567435_6	211165.AJLN01000116_gene3438	5.092e-110	368.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS2_k127_2567435_20	926569.ANT_20880	5.442e-37	148.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_2567435_11	926561.KB900618_gene55	5.19e-81	284.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS2_k127_2567435_25	1321778.HMPREF1982_00639	3.779e-21	95.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,2695Y@186813|unclassified Clostridiales	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
GDHHQS2_k127_2567435_1	273068.TTE2334	4.77e-157	513.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS2_k127_2567435_23	634956.Geoth_0831	2.604e-25	119.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1WEXZ@129337|Geobacillus	91061|Bacilli	EGP	Nucleoside H+ symporter	ywbF	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
GDHHQS2_k127_2567435_0	357808.RoseRS_4538	1.426e-158	506.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_2567435_2	357808.RoseRS_4538	1.69e-151	484.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_2567435_8	926569.ANT_08060	3.275e-104	348.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS2_k127_2567435_5	324602.Caur_1110	1.578e-118	399.0	COG1472@1|root,COG1472@2|Bacteria,2G8JU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GDHHQS2_k127_2567435_31	326427.Cagg_1686	9.593e-12	68.0	COG1653@1|root,COG1653@2|Bacteria,2G7RQ@200795|Chloroflexi,377M8@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_2605502_34	749927.AMED_6722	2.689e-21	104.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4E341@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_2605502_28	479434.Sthe_1898	4.976e-36	145.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS2_k127_2605502_32	518766.Rmar_2263	7.976e-28	116.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1FJJ0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS2_k127_2605502_20	246194.CHY_0215	5.422e-61	213.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,42G92@68295|Thermoanaerobacterales	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS2_k127_2605502_22	926569.ANT_18700	3.695e-56	226.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GDHHQS2_k127_2605502_9	326427.Cagg_1337	6.655e-86	290.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_2605502_37	1288484.APCS01000081_gene2146	1.577e-17	88.0	COG3947@1|root,COG3947@2|Bacteria,1WMI5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing CheY-like receiver and SARP domains	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Response_reg
GDHHQS2_k127_2605502_30	326427.Cagg_2554	1.137e-30	139.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
GDHHQS2_k127_2605502_40	357808.RoseRS_3766	1.349e-13	84.0	COG2172@1|root,COG2172@2|Bacteria,2GB4J@200795|Chloroflexi,377WY@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS2_k127_2605502_39	1240349.ANGC01000038_gene3219	2.389e-15	79.0	COG1366@1|root,COG1366@2|Bacteria,2HI3J@201174|Actinobacteria,4G2KS@85025|Nocardiaceae	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS2_k127_2605502_0	179408.Osc7112_4771	2.883e-194	621.0	COG2114@1|root,COG2114@2|Bacteria,1G335@1117|Cyanobacteria,1H8VG@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS2_k127_2605502_4	1128421.JAGA01000002_gene1889	3.424e-133	430.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	glxR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	iJN678.mmsB	NAD_binding_11,NAD_binding_2
GDHHQS2_k127_2605502_31	652103.Rpdx1_0645	5.186e-29	121.0	COG5528@1|root,COG5528@2|Bacteria,1RIIR@1224|Proteobacteria,2UB22@28211|Alphaproteobacteria,3K5TR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GDHHQS2_k127_2605502_29	1464048.JNZS01000029_gene1775	8.819e-34	138.0	COG1280@1|root,COG1280@2|Bacteria,2IIQ3@201174|Actinobacteria,4DDUC@85008|Micromonosporales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS2_k127_2605502_3	526227.Mesil_0169	1.374e-134	436.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GDHHQS2_k127_2605502_14	521045.Kole_1963	1.482e-73	257.0	arCOG14015@1|root,30H02@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_17	877418.ATWV01000006_gene2257	1.01e-65	241.0	COG3440@1|root,COG3440@2|Bacteria,2JATB@203691|Spirochaetes	203691|Spirochaetes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
GDHHQS2_k127_2605502_35	1280948.HY36_01310	6.988e-19	93.0	2ECCI@1|root,336AU@2|Bacteria,1PTNQ@1224|Proteobacteria,2V5I0@28211|Alphaproteobacteria,440HA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_23	1485544.JQKP01000003_gene82	1.244e-53	191.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,44VWV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GDHHQS2_k127_2605502_21	1128427.KB904821_gene2484	6.227e-57	213.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
GDHHQS2_k127_2605502_27	1033734.CAET01000002_gene4421	2.317e-39	155.0	COG2755@1|root,COG2755@2|Bacteria,1V1QW@1239|Firmicutes,4HGWC@91061|Bacilli,1ZGV5@1386|Bacillus	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS2_k127_2605502_18	926569.ANT_07530	1.031e-62	224.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS2_k127_2605502_44	1122609.AUGT01000013_gene4106	6.442e-05	54.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4DSW5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_6	675635.Psed_0202	1.52e-92	320.0	COG2909@1|root,COG2909@2|Bacteria,2HQST@201174|Actinobacteria,4E9R0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GDHHQS2_k127_2605502_12	926569.ANT_11480	8.315e-81	282.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_2605502_7	571166.KI421509_gene2039	4.739e-92	309.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_2605502_26	1382306.JNIM01000001_gene144	6.796e-44	167.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS2_k127_2605502_33	926569.ANT_30450	1.908e-27	118.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_38	525903.Taci_1634	1.402e-16	88.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,3TAJE@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GDHHQS2_k127_2605502_13	106370.Francci3_0500	7.972e-75	254.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4ESE6@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_15	926550.CLDAP_16290	2.847e-71	250.0	COG2301@1|root,COG2301@2|Bacteria,2G6EA@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the HpcH HpaI aldolase family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
GDHHQS2_k127_2605502_24	1489678.RDMS_03315	4.594e-51	184.0	COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GDHHQS2_k127_2605502_41	358823.DF19_36780	4.866e-13	72.0	2EVD7@1|root,33NTQ@2|Bacteria,2IRUN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2605502_16	926569.ANT_25670	4.306e-67	250.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
GDHHQS2_k127_2605502_5	926569.ANT_30570	4.213e-123	405.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GDHHQS2_k127_2605502_1	195103.CPF_1255	1.796e-163	532.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,36E95@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS2_k127_2605502_2	1121382.JQKG01000005_gene3374	8.25e-154	499.0	COG0215@1|root,COG0215@2|Bacteria,1WIEP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS2_k127_2605502_11	316274.Haur_3773	2.524e-81	278.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi,375AH@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS2_k127_2605502_42	439235.Dalk_2131_NEW	1.056e-12	82.0	COG3291@1|root,COG3292@1|root,COG3291@2|Bacteria,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
GDHHQS2_k127_2605502_10	316274.Haur_0123	2.474e-85	288.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi,374T9@32061|Chloroflexia	32061|Chloroflexia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS2_k127_2605502_19	459495.SPLC1_S200730	7.718e-62	215.0	COG0080@1|root,COG0080@2|Bacteria,1G4ZJ@1117|Cyanobacteria,1HAME@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS2_k127_2605502_8	926569.ANT_18990	7.995e-89	297.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
GDHHQS2_k127_2605502_43	1128421.JAGA01000002_gene1607	2.848e-07	56.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
GDHHQS2_k127_2605502_36	1043493.BBLU01000003_gene2386	7.393e-19	86.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GDHHQS2_k127_2605502_25	479434.Sthe_1611	2.463e-47	171.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS2_k127_2808512_5	1444309.JAQG01000005_gene4288	1.253e-92	317.0	COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli,26TVQ@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS2_k127_2808512_18	460265.Mnod_3437	2.866e-30	129.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TSQ4@28211|Alphaproteobacteria,1JTNP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_2808512_17	404380.Gbem_2014	1.019e-41	160.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2808512_22	1157634.KB912946_gene3045	1.375e-19	96.0	COG0508@1|root,COG0508@2|Bacteria,2GQQK@201174|Actinobacteria	201174|Actinobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2808512_13	1122137.AQXF01000005_gene1059	5.356e-52	189.0	COG4430@1|root,COG4430@2|Bacteria,1RGC9@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
GDHHQS2_k127_2808512_12	335659.S23_12870	6.064e-53	190.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,2UA4T@28211|Alphaproteobacteria,3JYP2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
GDHHQS2_k127_2808512_1	159087.Daro_1706	8.013e-166	525.0	COG0702@1|root,COG0702@2|Bacteria,1PM6M@1224|Proteobacteria,2VMCW@28216|Betaproteobacteria,2KY3I@206389|Rhodocyclales	206389|Rhodocyclales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS2_k127_2808512_0	383372.Rcas_4397	2.716e-171	548.0	COG0863@1|root,COG0863@2|Bacteria,2G7IH@200795|Chloroflexi,376KM@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS2_k127_2808512_4	383372.Rcas_4398	1.06e-99	332.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS2_k127_2808512_27	1027371.GOALK_093_00330	0.0009509	51.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5,Helicase_C,ResIII
GDHHQS2_k127_2808512_11	1459636.NTE_02189	1.949e-56	204.0	COG0262@1|root,arCOG01490@2157|Archaea	2157|Archaea	H	Belongs to the dihydrofolate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_2808512_20	926550.CLDAP_34220	2.488e-23	101.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_2808512_8	1121930.AQXG01000007_gene490	7.948e-65	255.0	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2808512_26	388739.RSK20926_22004	4.334e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2P49S@2433|Roseobacter	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2,PA14
GDHHQS2_k127_2808512_7	926550.CLDAP_09190	7.706e-75	260.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_2808512_15	1123368.AUIS01000023_gene896	7.253e-50	192.0	COG2267@1|root,COG2267@2|Bacteria,1QYVT@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_2808512_6	767817.Desgi_3212	3.737e-85	297.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,260NR@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
GDHHQS2_k127_2808512_16	313596.RB2501_12022	9.315e-46	177.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_2808512_9	219305.MCAG_00296	3.127e-62	231.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
GDHHQS2_k127_2808512_2	1487953.JMKF01000073_gene3678	1.061e-148	498.0	COG0659@1|root,COG0659@2|Bacteria,1G3AY@1117|Cyanobacteria,1H9Q2@1150|Oscillatoriales	1117|Cyanobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
GDHHQS2_k127_2808512_3	1122222.AXWR01000026_gene1658	4.063e-137	448.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS2_k127_2808512_14	1121930.AQXG01000001_gene1036	1.126e-51	197.0	2ES9V@1|root,33JUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2808512_24	1463887.KL590048_gene2922	1.048e-15	81.0	2B9Y4@1|root,323BK@2|Bacteria,2H7YW@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_2808512_23	489825.LYNGBM3L_30140	1.191e-17	85.0	COG2442@1|root,COG2442@2|Bacteria,1G6VW@1117|Cyanobacteria,1HBPI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_2808512_21	266117.Rxyl_2863	1.663e-22	100.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
GDHHQS2_k127_2808512_10	926569.ANT_16060	4.331e-57	204.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GDHHQS2_k127_2843124_0	626418.bglu_2g16130	1.764e-182	576.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2VNA0@28216|Betaproteobacteria,1K69X@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
GDHHQS2_k127_2843124_1	404380.Gbem_3471	2.125e-27	115.0	COG0616@1|root,COG0616@2|Bacteria,1MY1I@1224|Proteobacteria,42PFB@68525|delta/epsilon subdivisions,2WSJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
GDHHQS2_k127_2863140_21	926569.ANT_15430	7.029e-63	222.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
GDHHQS2_k127_2863140_29	926569.ANT_27650	4.982e-21	96.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS2_k127_2863140_7	314285.KT71_18426	2.639e-189	603.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
GDHHQS2_k127_2863140_2	864051.BurJ1DRAFT_2685	6.808e-268	859.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GDHHQS2_k127_2863140_22	864051.BurJ1DRAFT_2686	1.488e-62	221.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS2_k127_2863140_13	566466.NOR53_798	2.456e-109	367.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
GDHHQS2_k127_2863140_25	926569.ANT_28850	4.759e-50	181.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
GDHHQS2_k127_2863140_28	926550.CLDAP_25550	3.514e-48	195.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GDHHQS2_k127_2863140_19	1382306.JNIM01000001_gene1045	6.824e-68	237.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_2863140_31	639282.DEFDS_1384	2.896e-11	74.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
GDHHQS2_k127_2863140_23	589924.Ferp_0123	2.659e-57	209.0	COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,246KB@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
GDHHQS2_k127_2863140_20	1121451.DESAM_10136	1.085e-67	245.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS2_k127_2863140_8	373903.Hore_08780	9.305e-164	531.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WA8J@53433|Halanaerobiales	186801|Clostridia	S	PFAM ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS2_k127_2863140_16	1313172.YM304_01530	1.962e-92	315.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
GDHHQS2_k127_2863140_15	1487923.DP73_12465	1.04e-93	319.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,26193@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_2863140_14	1313172.YM304_01550	8.037e-97	329.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_2863140_0	926550.CLDAP_05320	0.0	1159.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GDHHQS2_k127_2863140_17	926550.CLDAP_05310	4.456e-78	271.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS2_k127_2863140_34	1385935.N836_16630	3.484e-06	53.0	COG1413@1|root,COG1413@2|Bacteria,1G1H5@1117|Cyanobacteria,1HGMN@1150|Oscillatoriales	1117|Cyanobacteria	C	Domain of unknown function (DUF4132)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132
GDHHQS2_k127_2863140_27	1047013.AQSP01000062_gene1209	1.379e-48	203.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	XK27_02215	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
GDHHQS2_k127_2863140_32	452637.Oter_2514	2.822e-09	73.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46VP5@74201|Verrucomicrobia,3K8IM@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS2_k127_2863140_33	1150474.JQJI01000011_gene56	2.27e-07	66.0	COG1520@1|root,COG4733@1|root,COG4964@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria,COG4964@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_2863140_35	946483.Cenrod_1840	0.0001245	57.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,4A9WS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_2863140_30	247490.KSU1_C0300	2.135e-14	90.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_2863140_12	864051.BurJ1DRAFT_3700	1.494e-118	436.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
GDHHQS2_k127_2863140_26	471854.Dfer_0264	3.058e-49	206.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
GDHHQS2_k127_2863140_11	485913.Krac_0431	2.1e-126	419.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GDHHQS2_k127_2863140_10	448385.sce3735	4.649e-151	488.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS2_k127_2863140_4	404589.Anae109_1753	4.452e-244	764.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS2_k127_2863140_18	1128421.JAGA01000002_gene1557	2.744e-70	243.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GDHHQS2_k127_2863140_5	316274.Haur_4441	5.867e-227	711.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GDHHQS2_k127_2863140_6	1254432.SCE1572_22465	7.139e-226	711.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS2_k127_2863140_9	448385.sce3732	1.445e-154	494.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2YU99@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
GDHHQS2_k127_2863140_24	1242864.D187_003311	3.926e-56	201.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2Z0D5@29|Myxococcales	28221|Deltaproteobacteria	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
GDHHQS2_k127_2863140_1	926569.ANT_03260	9.635e-287	889.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_2863140_3	926569.ANT_03250	1.654e-259	811.0	COG0129@1|root,COG0129@2|Bacteria,2G5QW@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS2_k127_2880992_11	1408473.JHXO01000007_gene740	1.03e-34	145.0	2ET8I@1|root,33KSM@2|Bacteria,4NZEX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2880992_15	316274.Haur_3935	3.504e-19	98.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_2880992_12	484019.THA_1785	3.027e-33	145.0	COG0642@1|root,COG3887@1|root,COG2205@2|Bacteria,COG3887@2|Bacteria,2GC1Q@200918|Thermotogae	200918|Thermotogae	F	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS2_k127_2880992_22	765420.OSCT_0734	7.97e-08	61.0	COG3391@1|root,COG3391@2|Bacteria,2G9E4@200795|Chloroflexi	200795|Chloroflexi	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2880992_0	926550.CLDAP_27990	1.051e-130	428.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_2880992_23	1220534.B655_1927	2.345e-07	62.0	COG1429@1|root,COG1572@1|root,arCOG02532@2157|Archaea,arCOG03022@2157|Archaea,2XT6P@28890|Euryarchaeota,23PGH@183925|Methanobacteria	183925|Methanobacteria	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
GDHHQS2_k127_2880992_14	1121272.KB903290_gene4739	4.039e-20	98.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2880992_10	330214.NIDE4035	9.497e-39	156.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_2880992_4	765420.OSCT_1869	2.296e-66	237.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,376S8@32061|Chloroflexia	32061|Chloroflexia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
GDHHQS2_k127_2880992_5	479434.Sthe_3084	4.241e-62	222.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
GDHHQS2_k127_2880992_2	861299.J421_0978	1.11e-74	252.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
GDHHQS2_k127_2880992_8	479432.Sros_6982	4.069e-53	192.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJS4@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_2880992_1	1122223.KB890700_gene2058	1.508e-117	392.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_2880992_6	1128421.JAGA01000002_gene1190	1.478e-61	216.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
GDHHQS2_k127_2880992_7	118166.JH976537_gene4360	4.397e-59	212.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1HE9G@1150|Oscillatoriales	1117|Cyanobacteria	S	3-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
GDHHQS2_k127_2880992_13	479434.Sthe_1389	2.918e-25	121.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2880992_9	4641.GSMUA_Achr11P02240_001	6.131e-42	162.0	COG0580@1|root,KOG0223@2759|Eukaryota,37HHG@33090|Viridiplantae,3GA6H@35493|Streptophyta,3KTA6@4447|Liliopsida	35493|Streptophyta	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	GO:0000325,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006833,GO:0008150,GO:0009705,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0031090,GO:0031224,GO:0031226,GO:0034220,GO:0042044,GO:0042807,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098588,GO:0098805	-	ko:K09873	-	-	-	-	ko00000,ko02000	1.A.8.10	-	-	MIP
GDHHQS2_k127_2880992_3	383372.Rcas_1125	1.799e-67	248.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_2880992_16	360911.EAT1b_1873	1.237e-12	73.0	2DQT5@1|root,338GV@2|Bacteria,1VEES@1239|Firmicutes,4HNWP@91061|Bacilli	91061|Bacilli	-	-	M1-488	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066750_12	1304866.K413DRAFT_2834	7.169e-05	53.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,36DXC@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
GDHHQS2_k127_3066750_1	596151.DesfrDRAFT_0413	4.524e-101	335.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MANJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
GDHHQS2_k127_3066750_5	525904.Tter_0233	7.738e-28	123.0	COG2227@1|root,COG2227@2|Bacteria,2NQ8I@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_3066750_7	391625.PPSIR1_25921	1.298e-13	83.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066750_0	1128421.JAGA01000003_gene3696	2.236e-171	558.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS2_k127_3066750_13	329726.AM1_3967	0.000928	50.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1G0VA@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
GDHHQS2_k127_3066750_9	317619.ANKN01000117_gene1303	1.848e-08	64.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
GDHHQS2_k127_3066750_6	192952.MM_1264	1.019e-21	102.0	COG5513@1|root,arCOG03547@2157|Archaea,2Y4G7@28890|Euryarchaeota,2NB6K@224756|Methanomicrobia	224756|Methanomicrobia	G	serine-type aminopeptidase activity	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	-
GDHHQS2_k127_3066750_8	1144275.COCOR_07570	9.361e-13	74.0	28QBH@1|root,2ZCU3@2|Bacteria,1PBHU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3066750_3	526227.Mesil_1024	1.937e-38	149.0	COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_3066750_4	324057.Pjdr2_5285	4.77e-29	123.0	COG1714@1|root,COG1714@2|Bacteria,1V7WG@1239|Firmicutes,4HK3X@91061|Bacilli	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS2_k127_3066750_2	1088721.NSU_1615	8.171e-62	220.0	COG1432@1|root,COG1432@2|Bacteria,1RJ15@1224|Proteobacteria,2UCYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
GDHHQS2_k127_3066750_11	497321.C664_02120	4.564e-08	65.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,2KW5F@206389|Rhodocyclales	206389|Rhodocyclales	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
GDHHQS2_k127_3066750_10	1463901.JOIY01000033_gene3699	3.218e-08	64.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_3136719_24	177439.DP2017	2.356e-20	98.0	2CEVA@1|root,34921@2|Bacteria,1NZTW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_12	880073.Calab_3028	1.465e-52	192.0	COG1943@1|root,COG1943@2|Bacteria,2NRVN@2323|unclassified Bacteria	2|Bacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS2_k127_3136719_0	926569.ANT_24980	1.12e-259	826.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS2_k127_3136719_34	1385512.N784_09485	0.0001871	52.0	COG4932@1|root,COG4932@2|Bacteria,1UXD9@1239|Firmicutes,4I2J1@91061|Bacilli,2YBSI@289201|Pontibacillus	91061|Bacilli	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_5	926550.CLDAP_01050	3.245e-127	415.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS2_k127_3136719_27	208444.JNYY01000021_gene7	1.217e-16	93.0	2BZ9A@1|root,32T13@2|Bacteria,2GPHM@201174|Actinobacteria,4EDCC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_1	880071.Fleli_0094	6.661e-214	685.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS2_k127_3136719_18	44251.PDUR_11590	4.441e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,1V5RB@1239|Firmicutes,4HHZF@91061|Bacilli,26XWG@186822|Paenibacillaceae	91061|Bacilli	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_3136719_2	290315.Clim_1236	1.834e-180	597.0	COG0433@1|root,COG0433@2|Bacteria,1FEIF@1090|Chlorobi	1090|Chlorobi	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
GDHHQS2_k127_3136719_8	324602.Caur_0790	1.897e-79	280.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi,37519@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS2_k127_3136719_19	251229.Chro_3808	6.673e-35	136.0	2CCSR@1|root,32RWC@2|Bacteria,1GEQ5@1117|Cyanobacteria,3VKJG@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_3136719_15	1278073.MYSTI_02116	7.969e-42	165.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2YVHS@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_3136719_7	926569.ANT_00470	2.27e-81	279.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3136719_32	933115.GPDM_06685	3.847e-06	53.0	29QX2@1|root,30BXP@2|Bacteria,1U8UE@1239|Firmicutes,4IISR@91061|Bacilli,26HXE@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_10	926569.ANT_14150	1.801e-73	263.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
GDHHQS2_k127_3136719_16	221288.JH992901_gene3557	2.697e-38	149.0	COG1403@1|root,COG1403@2|Bacteria,1G5US@1117|Cyanobacteria,1JM54@1189|Stigonemataceae	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GDHHQS2_k127_3136719_30	272134.KB731324_gene4910	1.763e-09	64.0	2BWVV@1|root,32R08@2|Bacteria,1G7AG@1117|Cyanobacteria,1HC1N@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_21	1382306.JNIM01000001_gene1264	4.675e-31	132.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS2_k127_3136719_14	926569.ANT_31660	3.989e-43	166.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GDHHQS2_k127_3136719_28	713586.KB900536_gene2577	1.193e-12	78.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_3136719_6	926569.ANT_15160	4.969e-95	320.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GDHHQS2_k127_3136719_25	6087.XP_004211334.1	2.598e-20	101.0	COG0666@1|root,KOG4177@2759|Eukaryota,39M8Y@33154|Opisthokonta,3CNW2@33208|Metazoa	33208|Metazoa	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
GDHHQS2_k127_3136719_4	1120972.AUMH01000004_gene1404	9.476e-141	463.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,2786F@186823|Alicyclobacillaceae	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
GDHHQS2_k127_3136719_22	383372.Rcas_1007	2.679e-29	117.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_3136719_20	391612.CY0110_10092	2.704e-31	126.0	COG1598@1|root,COG1598@2|Bacteria,1GIE2@1117|Cyanobacteria,3KKIY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3136719_13	378806.STAUR_7783	1.539e-50	184.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,43818@68525|delta/epsilon subdivisions,2X9US@28221|Deltaproteobacteria,2YV7Z@29|Myxococcales	28221|Deltaproteobacteria	F	Shikimate kinase	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
GDHHQS2_k127_3136719_29	869210.Marky_2134	2.235e-12	73.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GDHHQS2_k127_3136719_3	926569.ANT_09720	8.788e-169	554.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS2_k127_3136719_26	926550.CLDAP_08150	6.02e-18	90.0	COG2891@1|root,COG2891@2|Bacteria	2|Bacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
GDHHQS2_k127_3136719_17	926569.ANT_09700	9.681e-38	153.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS2_k127_3136719_31	383372.Rcas_1943	1.787e-06	61.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GDHHQS2_k127_3136719_11	1340493.JNIF01000003_gene3428	3.287e-70	245.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_3136719_9	1107311.Q767_15140	4.055e-74	250.0	298UU@1|root,2ZVYZ@2|Bacteria,4NPH1@976|Bacteroidetes,1I8RV@117743|Flavobacteriia,2NWGH@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_3159781_2	864702.OsccyDRAFT_2545	0.0	1122.0	COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_3159781_25	1121403.AUCV01000012_gene4045	4.674e-152	494.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS2_k127_3159781_98	267608.RSp0174	6.28e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2VTR5@28216|Betaproteobacteria,1K3MW@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_3159781_126	402777.KB235904_gene3444	2.782e-56	201.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS2_k127_3159781_106	357808.RoseRS_1416	5.877e-69	244.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS2_k127_3159781_21	1297570.MESS4_160088	6.203e-164	529.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS2_k127_3159781_51	1379698.RBG1_1C00001G1677	2.456e-118	390.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS2_k127_3159781_131	926569.ANT_02780	7.349e-55	202.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS2_k127_3159781_195	926550.CLDAP_20100	1.826e-12	74.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS2_k127_3159781_192	649638.Trad_2116	1e-13	79.0	COG0551@1|root,COG0551@2|Bacteria,1WK43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
GDHHQS2_k127_3159781_73	266117.Rxyl_2365	3.639e-87	298.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2GKBH@201174|Actinobacteria,4CPXP@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_3159781_206	1449048.JQKU01000030_gene4201	2.817e-07	62.0	2DWQF@1|root,341EX@2|Bacteria,2IJK7@201174|Actinobacteria,23F2Z@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_128	751944.HALDL1_10215	1.485e-55	205.0	COG0702@1|root,arCOG03015@2157|Archaea,2XVBX@28890|Euryarchaeota,23U9C@183963|Halobacteria	183963|Halobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GDHHQS2_k127_3159781_59	383372.Rcas_4186	4.737e-107	358.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,375TP@32061|Chloroflexia	32061|Chloroflexia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS2_k127_3159781_151	42256.RradSPS_1814	4.4e-40	168.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_3159781_211	227086.JGI_V11_48995	5.434e-05	54.0	COG0846@1|root,COG5033@1|root,KOG1905@2759|Eukaryota,KOG3149@2759|Eukaryota	2759|Eukaryota	K	chromatin organization	-	-	1.6.5.5,2.4.2.31	ko:K00344,ko:K11341,ko:K11416	ko04714,ko05230,map04714,map05230	-	-	-	ko00000,ko00001,ko01000,ko03036	-	-	-	SIR2,YEATS,zf-C3HC4
GDHHQS2_k127_3159781_202	1449050.JNLE01000003_gene1850	1.288e-08	66.0	COG4916@1|root,COG4916@2|Bacteria,1US40@1239|Firmicutes,24UZ0@186801|Clostridia	186801|Clostridia	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GDHHQS2_k127_3159781_178	391612.CY0110_00335	2.514e-21	104.0	COG0457@1|root,COG0457@2|Bacteria,1G7C5@1117|Cyanobacteria,3KIQY@43988|Cyanothece	1117|Cyanobacteria	S	Putative capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NKWYS
GDHHQS2_k127_3159781_99	1123320.KB889640_gene4470	7.035e-75	261.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GDHHQS2_k127_3159781_80	439235.Dalk_3095	4.7e-83	280.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS2_k127_3159781_209	1218352.B597_004970	2.812e-05	46.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1Z0JY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS2_k127_3159781_62	1380355.JNIJ01000071_gene5822	3.441e-105	361.0	COG2114@1|root,COG2114@2|Bacteria,1R51D@1224|Proteobacteria,2TT6W@28211|Alphaproteobacteria,3JVJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS2_k127_3159781_43	1267533.KB906735_gene4630	2.451e-125	413.0	COG0475@1|root,COG0475@2|Bacteria,3Y9G2@57723|Acidobacteria,2JNWD@204432|Acidobacteriia	204432|Acidobacteriia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS2_k127_3159781_194	297246.lpp0353	1.478e-12	73.0	COG4191@1|root,COG4191@2|Bacteria,1R3RN@1224|Proteobacteria,1S55D@1236|Gammaproteobacteria,1JD0X@118969|Legionellales	118969|Legionellales	T	Histidine kinase-like ATPases	fixL	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3
GDHHQS2_k127_3159781_35	1254432.SCE1572_48965	4.587e-137	445.0	COG3287@1|root,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,42Q8C@68525|delta/epsilon subdivisions,2WWR9@28221|Deltaproteobacteria,2YU1Q@29|Myxococcales	28221|Deltaproteobacteria	M	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS2_k127_3159781_42	383372.Rcas_1353	1.679e-126	422.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi,376C8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,Wzz
GDHHQS2_k127_3159781_83	479432.Sros_0608	3.029e-82	279.0	COG5395@1|root,COG5395@2|Bacteria,2IHVI@201174|Actinobacteria,4EJNA@85012|Streptosporangiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
GDHHQS2_k127_3159781_179	1082931.KKY_2035	3.26e-21	96.0	COG1476@1|root,COG1476@2|Bacteria,1N7BB@1224|Proteobacteria,2UGNF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS2_k127_3159781_187	1122915.AUGY01000011_gene3989	8.444e-17	86.0	2EGE1@1|root,33A5Y@2|Bacteria,1VV4C@1239|Firmicutes,4HVGE@91061|Bacilli,26YKG@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_38	926569.ANT_06210	1.995e-133	447.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
GDHHQS2_k127_3159781_177	159087.Daro_2502	1.563e-21	106.0	29AU1@1|root,2ZXTE@2|Bacteria,1RFMX@1224|Proteobacteria,2W6I0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_82	1120971.AUCA01000049_gene794	1.04e-82	289.0	COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_3159781_86	926569.ANT_31200	6.591e-81	306.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_3159781_84	357808.RoseRS_3818	3.84e-82	278.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_118	552811.Dehly_1314	2.857e-60	224.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,34D12@301297|Dehalococcoidia	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,sCache_like
GDHHQS2_k127_3159781_165	82654.Pse7367_0741	1.274e-28	119.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_3159781_168	373994.Riv7116_6611	4.696e-28	119.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HNG1@1161|Nostocales	1117|Cyanobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_3159781_207	66373.JOFQ01000001_gene1549	6.102e-07	61.0	COG0477@1|root,COG2814@2|Bacteria,2GK86@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_3159781_108	1337936.IJ00_27275	2.418e-68	239.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
GDHHQS2_k127_3159781_158	926569.ANT_03600	1.213e-36	147.0	COG1225@1|root,COG1225@2|Bacteria,2G9KJ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_3159781_159	1123278.KB893592_gene6006	1.198e-34	135.0	COG2442@1|root,COG2442@2|Bacteria,4P60R@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_3159781_162	489825.LYNGBM3L_48860	1.001e-32	130.0	COG4634@1|root,COG4634@2|Bacteria,1G78I@1117|Cyanobacteria,1HFYH@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_186	926550.CLDAP_04900	4.983e-18	94.0	COG3391@1|root,COG4447@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_141	41431.PCC8801_1830	8.569e-47	188.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_3159781_143	41431.PCC8801_1830	2.112e-45	183.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_3159781_119	309801.trd_1606	3.417e-59	215.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_3159781_81	357808.RoseRS_3478	9.853e-83	284.0	COG2267@1|root,COG2267@2|Bacteria,2GBMR@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_3159781_4	926550.CLDAP_09520	6.249e-282	885.0	COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi	200795|Chloroflexi	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS2_k127_3159781_1	383372.Rcas_1874	0.0	1178.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi,376HX@32061|Chloroflexia	32061|Chloroflexia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
GDHHQS2_k127_3159781_70	1120949.KB903328_gene8859	2.549e-92	312.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4DH96@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GDHHQS2_k127_3159781_55	543632.JOJL01000054_gene204	9.637e-113	370.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4DIFW@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GDHHQS2_k127_3159781_24	28444.JODQ01000001_gene2375	4.676e-154	499.0	COG1653@1|root,COG1653@2|Bacteria,2I9M7@201174|Actinobacteria,4EQ61@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_3159781_50	324602.Caur_0365	6.269e-119	391.0	COG1609@1|root,COG1609@2|Bacteria,2G6GN@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_3159781_96	266117.Rxyl_0160	2.338e-75	265.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4CQ2W@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_3159781_117	479434.Sthe_1551	2.088e-60	226.0	COG4585@1|root,COG4585@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS2_k127_3159781_133	309807.SRU_0751	8.73e-54	201.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS2_k127_3159781_63	211114.JOEF01000001_gene7537	2.022e-104	347.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_3159781_196	1082933.MEA186_21009	3.22e-12	69.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,2TTSN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3159781_27	1128421.JAGA01000003_gene3296	1.872e-150	498.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Gal_mutarotas_2,Glyco_hydro_31,NPCBM_assoc
GDHHQS2_k127_3159781_16	1033806.HTIA_p2897	9.506e-172	561.0	COG1874@1|root,arCOG04085@2157|Archaea,2XTFD@28890|Euryarchaeota,23UBS@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
GDHHQS2_k127_3159781_97	326427.Cagg_0727	2.967e-75	267.0	COG0395@1|root,COG0395@2|Bacteria,2G6JM@200795|Chloroflexi,37760@32061|Chloroflexia	32061|Chloroflexia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_3159781_113	1219084.AP014508_gene907	5.446e-63	237.0	COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
GDHHQS2_k127_3159781_64	326427.Cagg_0729	1.643e-99	340.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi,377G1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
GDHHQS2_k127_3159781_100	1128421.JAGA01000003_gene3074	1.051e-74	263.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_3159781_116	324602.Caur_0124	2.866e-61	221.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
GDHHQS2_k127_3159781_20	926569.ANT_01780	5.064e-166	533.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_3159781_45	926569.ANT_01790	8.582e-123	403.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
GDHHQS2_k127_3159781_61	926569.ANT_01800	1.661e-105	348.0	COG0395@1|root,COG0395@2|Bacteria,2G5SY@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
GDHHQS2_k127_3159781_39	1144275.COCOR_02904	7.512e-132	431.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,42Y39@68525|delta/epsilon subdivisions,2WSYZ@28221|Deltaproteobacteria,2YV2T@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GDHHQS2_k127_3159781_26	1073999.BN137_3986	1.287e-151	489.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	galactose-1-phosphate uridylyltransferase	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
GDHHQS2_k127_3159781_156	1131462.DCF50_p2804	8.891e-37	148.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_182	926569.ANT_11770	1.047e-19	93.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_3159781_175	398767.Glov_0564	1.71e-22	101.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS2_k127_3159781_189	497964.CfE428DRAFT_3341	2.51e-15	80.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_3341|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_173	1123508.JH636446_gene6356	1.133e-24	121.0	COG2197@1|root,COG2203@1|root,COG3920@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936,ko:K03406,ko:K21009	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00839	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,GerE,HATPase_c,HATPase_c_2,H_kinase_N,HisKA,HisKA_2,MCPsignal,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_3159781_104	28072.Nos7524_1724	2.374e-70	267.0	COG0745@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1HKPC@1161|Nostocales	1117|Cyanobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_184	5786.XP_003288945.1	1.353e-18	97.0	28XHJ@1|root,2RC2G@2759|Eukaryota,3XAAT@554915|Amoebozoa	554915|Amoebozoa	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_154	1205753.A989_04723	5.071e-38	160.0	COG1657@1|root,COG1657@2|Bacteria,1MVWK@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
GDHHQS2_k127_3159781_198	748247.AZKH_2727	9.468e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VU99@28216|Betaproteobacteria,2KZ14@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_3159781_132	1178482.BJB45_11795	4.085e-54	207.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
GDHHQS2_k127_3159781_174	765420.OSCT_3027	5.449e-23	108.0	COG1556@1|root,COG1556@2|Bacteria,2G7BK@200795|Chloroflexi,37778@32061|Chloroflexia	32061|Chloroflexia	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
GDHHQS2_k127_3159781_37	383372.Rcas_0811	2.071e-134	444.0	COG1139@1|root,COG1139@2|Bacteria,2G665@200795|Chloroflexi,37659@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
GDHHQS2_k127_3159781_109	1322246.BN4_20092	4.394e-68	239.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2M8X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
GDHHQS2_k127_3159781_3	649638.Trad_2963	0.0	1063.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1WJR6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
GDHHQS2_k127_3159781_10	326427.Cagg_3315	7.556e-204	641.0	COG4806@1|root,COG4806@2|Bacteria,2GAHK@200795|Chloroflexi,37666@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
GDHHQS2_k127_3159781_19	266117.Rxyl_1685	4.626e-167	539.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4CPQB@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_3159781_136	1128421.JAGA01000002_gene1477	3.904e-51	183.0	COG3254@1|root,COG3254@2|Bacteria	2|Bacteria	S	rhamnose metabolic process	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
GDHHQS2_k127_3159781_34	1128421.JAGA01000002_gene1478	2.127e-138	449.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	rhaS	-	-	ko:K02058,ko:K10559	ko02010,map02010	M00220,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.9	-	-	Peripla_BP_4
GDHHQS2_k127_3159781_46	1128421.JAGA01000002_gene1479	2.944e-122	406.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	rhaQ	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
GDHHQS2_k127_3159781_52	1128421.JAGA01000002_gene1480	2.787e-118	390.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
GDHHQS2_k127_3159781_18	1172181.KB911703_gene378	8.009e-170	547.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
GDHHQS2_k127_3159781_153	696281.Desru_3141	3.824e-38	163.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	-	-	-	ko:K02081,ko:K02530	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GDHHQS2_k127_3159781_121	234267.Acid_5935	1.317e-58	226.0	COG1414@1|root,COG1879@1|root,COG1414@2|Bacteria,COG1879@2|Bacteria,3Y3RJ@57723|Acidobacteria	57723|Acidobacteria	K	IclR helix-turn-helix domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	HTH_IclR,Peripla_BP_4
GDHHQS2_k127_3159781_172	65393.PCC7424_3198	4.262e-25	118.0	COG1357@1|root,COG1357@2|Bacteria,1G3EU@1117|Cyanobacteria,3KH0B@43988|Cyanothece	1117|Cyanobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
GDHHQS2_k127_3159781_105	448385.sce4070	5.313e-70	246.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,42QZ4@68525|delta/epsilon subdivisions,2WUIV@28221|Deltaproteobacteria,2YUFC@29|Myxococcales	28221|Deltaproteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
GDHHQS2_k127_3159781_171	572477.Alvin_1750	2.304e-25	118.0	COG0642@1|root,COG3437@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1T4M1@1236|Gammaproteobacteria,1WYGE@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
GDHHQS2_k127_3159781_146	552811.Dehly_0999	5.492e-45	171.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,34DEA@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_169	552811.Dehly_0866	5.753e-28	122.0	COG0745@1|root,COG0745@2|Bacteria,2GAPD@200795|Chloroflexi,34CYY@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_212	526222.Desal_2686	6.702e-05	53.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1PZ3S@1224|Proteobacteria,435PM@68525|delta/epsilon subdivisions,2X03J@28221|Deltaproteobacteria,2MA9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF_3
GDHHQS2_k127_3159781_67	357808.RoseRS_2395	1.532e-96	325.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_3159781_32	266117.Rxyl_2668	1.031e-139	460.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CQCT@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4
GDHHQS2_k127_3159781_77	266117.Rxyl_2669	4.774e-85	299.0	COG4267@1|root,COG4267@2|Bacteria,2IE76@201174|Actinobacteria	201174|Actinobacteria	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
GDHHQS2_k127_3159781_30	365044.Pnap_1640	2.902e-143	488.0	28KNN@1|root,2ZA6V@2|Bacteria,1RFGD@1224|Proteobacteria,2W256@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_185	929556.Solca_0050	2.914e-18	100.0	COG1470@1|root,COG3209@1|root,COG4932@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
GDHHQS2_k127_3159781_93	765420.OSCT_3196	4.79e-77	283.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_3159781_147	926569.ANT_28000	5.695e-44	185.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_3159781_201	868864.Dester_0325	1.257e-08	60.0	COG2801@1|root,COG2801@2|Bacteria,2G3YF@200783|Aquificae	200783|Aquificae	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,HTH_Tnp_Tc3_2,rve,rve_3
GDHHQS2_k127_3159781_78	383372.Rcas_2661	3.076e-84	286.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,377FQ@32061|Chloroflexia	32061|Chloroflexia	C	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS2_k127_3159781_112	443143.GM18_2836	4.114e-63	224.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,43VXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS2_k127_3159781_6	383372.Rcas_2659	4.032e-254	813.0	COG0474@1|root,COG0474@2|Bacteria,2G85U@200795|Chloroflexi,376M7@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GDHHQS2_k127_3159781_199	1435356.Y013_11115	2.403e-10	74.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4FYAC@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_3159781_15	62928.azo2448	2.28e-172	548.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2VIVU@28216|Betaproteobacteria,2KXRT@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD binding domain	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
GDHHQS2_k127_3159781_102	1382356.JQMP01000003_gene1397	3.974e-73	256.0	COG0179@1|root,COG0179@2|Bacteria,2G6HH@200795|Chloroflexi,27Z1N@189775|Thermomicrobia	189775|Thermomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_3159781_14	479434.Sthe_2815	4.001e-178	563.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,27XXF@189775|Thermomicrobia	189775|Thermomicrobia	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS2_k127_3159781_144	1448860.BBJO01000042_gene1756	2.326e-45	180.0	COG4177@1|root,arCOG01274@2157|Archaea,2XVR5@28890|Euryarchaeota,241E9@183963|Halobacteria	183963|Halobacteria	E	branched-chain amino acid transport system, permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3159781_125	335543.Sfum_2141	7.701e-57	209.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3159781_90	383372.Rcas_2298	8.927e-79	271.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS2_k127_3159781_107	1118054.CAGW01000014_gene246	9.626e-69	242.0	COG0411@1|root,COG0411@2|Bacteria,1TRME@1239|Firmicutes	2|Bacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
GDHHQS2_k127_3159781_140	1218075.BAYA01000028_gene5734	4.497e-47	186.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2VPWN@28216|Betaproteobacteria,1KAPB@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS2_k127_3159781_33	1123388.AQWU01000069_gene182	8.753e-139	447.0	COG0346@1|root,COG0346@2|Bacteria,1WJN0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_3159781_68	926550.CLDAP_40920	5.557e-96	321.0	COG3971@1|root,COG3971@2|Bacteria,2G7K0@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Hydratase decarboxylase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
GDHHQS2_k127_3159781_53	1234664.AMRO01000077_gene3270	1.126e-114	376.0	COG2021@1|root,COG2021@2|Bacteria,1V2V2@1239|Firmicutes,4ITVQ@91061|Bacilli,1WEYE@129337|Geobacillus	91061|Bacilli	E	alpha/beta hydrolase fold	-	-	3.7.1.9	ko:K10216	ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R02604,R05362,R05865	RC00272,RC00753,RC00754,RC00755,RC01337,RC01485	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GDHHQS2_k127_3159781_17	326427.Cagg_2034	5.879e-170	542.0	COG0119@1|root,COG0119@2|Bacteria,2G7XM@200795|Chloroflexi,376A4@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
GDHHQS2_k127_3159781_28	309801.trd_1393	1.839e-145	466.0	COG4569@1|root,COG4569@2|Bacteria,2G7WV@200795|Chloroflexi,27Z3Q@189775|Thermomicrobia	189775|Thermomicrobia	Q	Prokaryotic acetaldehyde dehydrogenase, dimerisation	-	-	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
GDHHQS2_k127_3159781_87	1123388.AQWU01000069_gene184	2.275e-80	275.0	COG1414@1|root,COG1414@2|Bacteria,1WJRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Transcriptional regulator, IclR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GDHHQS2_k127_3159781_145	1382306.JNIM01000001_gene1538	2.394e-45	171.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	pcaC	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
GDHHQS2_k127_3159781_65	1231391.AMZF01000002_gene3227	1.333e-97	329.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,2W8YA@28216|Betaproteobacteria,3T705@506|Alcaligenaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3159781_56	1245471.PCA10_31710	2.391e-112	369.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,1RXET@1236|Gammaproteobacteria,1YIK9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3159781_94	1410620.SHLA_2c000690	5.466e-76	261.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSMP@28211|Alphaproteobacteria,4BBBS@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS2_k127_3159781_91	388051.AUFE01000043_gene3314	1.598e-77	266.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2VZHK@28216|Betaproteobacteria,1K943@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS2_k127_3159781_75	948106.AWZT01000038_gene1188	3.789e-86	293.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2VMB9@28216|Betaproteobacteria,1K1M2@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.37	ko:K04098	ko00361,ko00362,ko01100,ko01120,map00361,map00362,map01100,map01120	-	R03891,R04061	RC00388,RC01016	ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
GDHHQS2_k127_3159781_22	196367.JNFG01000201_gene2743	1.607e-162	524.0	COG0683@1|root,COG0683@2|Bacteria,1N0MT@1224|Proteobacteria,2W72I@28216|Betaproteobacteria,1K7JF@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
GDHHQS2_k127_3159781_135	383372.Rcas_2409	1.51e-51	188.0	COG1853@1|root,COG1853@2|Bacteria,2G8Z4@200795|Chloroflexi,377AM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS2_k127_3159781_5	357808.RoseRS_2569	8.217e-262	815.0	COG2368@1|root,COG2368@2|Bacteria,2G7XE@200795|Chloroflexi,3764P@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
GDHHQS2_k127_3159781_163	1440053.JOEI01000032_gene5402	3.959e-31	129.0	2B10M@1|root,31TDX@2|Bacteria,2GS84@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_167	1081644.IMCC13023_01780	2.764e-28	123.0	COG1396@1|root,COG1396@2|Bacteria,2IC4C@201174|Actinobacteria,4FSQU@85023|Microbacteriaceae	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3,HTH_31
GDHHQS2_k127_3159781_122	1218084.BBJK01000003_gene353	4.947e-58	216.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,1K0IU@119060|Burkholderiaceae	28216|Betaproteobacteria	C	maleylacetate reductase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS2_k127_3159781_120	926550.CLDAP_16790	3.944e-59	212.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_3159781_110	867845.KI911784_gene2653	1.744e-67	241.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
GDHHQS2_k127_3159781_23	926550.CLDAP_22740	7.387e-162	516.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
GDHHQS2_k127_3159781_79	926550.CLDAP_26530	8.568e-84	289.0	COG1609@1|root,COG1609@2|Bacteria,2G8C1@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_3159781_11	1280390.CBQR020000054_gene1064	7.105e-189	601.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes,4HT5T@91061|Bacilli,26RVV@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
GDHHQS2_k127_3159781_41	324602.Caur_2729	2.929e-130	426.0	COG1175@1|root,COG1175@2|Bacteria,2GAHR@200795|Chloroflexi,37678@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GDHHQS2_k127_3159781_40	1122962.AULH01000022_gene2906	1.401e-130	426.0	COG0395@1|root,COG0395@2|Bacteria,1MUMG@1224|Proteobacteria,2TVBP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type sugar transport system, permease component	aglG	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GDHHQS2_k127_3159781_13	1173028.ANKO01000077_gene5305	2.025e-180	574.0	COG2723@1|root,COG2723@2|Bacteria,1G3N0@1117|Cyanobacteria,1H7U0@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GDHHQS2_k127_3159781_9	525904.Tter_0330	7.314e-214	676.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GDHHQS2_k127_3159781_89	1280681.AUJZ01000027_gene2550	8.697e-79	278.0	COG1819@1|root,COG1819@2|Bacteria,1V1WQ@1239|Firmicutes,24NIJ@186801|Clostridia,4BYGC@830|Butyrivibrio	186801|Clostridia	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
GDHHQS2_k127_3159781_57	485913.Krac_0278	1.274e-108	361.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS2_k127_3159781_60	192952.MM_3157	5.509e-106	363.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
GDHHQS2_k127_3159781_69	41431.PCC8801_0005	2.155e-93	314.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GDHHQS2_k127_3159781_200	42256.RradSPS_0358	3.467e-10	72.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GDHHQS2_k127_3159781_72	977880.RALTA_A1335	1.14e-90	311.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2W1S8@28216|Betaproteobacteria,1K5IY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
GDHHQS2_k127_3159781_161	358681.BBR47_37950	2.692e-33	145.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	lacY	-	-	ko:K02532,ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3,2.A.1.5	-	-	LacY_symp,MFS_1,MFS_3
GDHHQS2_k127_3159781_115	326427.Cagg_2708	1.601e-61	229.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_3159781_88	765420.OSCT_0533	2.96e-80	278.0	COG0745@1|root,COG0745@2|Bacteria,2GAJP@200795|Chloroflexi,37683@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3159781_164	765420.OSCT_2177	5.092e-31	143.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	HEAT_2,STAS,Sulfate_transp,TLC,cNMP_binding
GDHHQS2_k127_3159781_44	479434.Sthe_0598	4.663e-123	436.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GDHHQS2_k127_3159781_47	326427.Cagg_0335	5.39e-122	395.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
GDHHQS2_k127_3159781_95	1173023.KE650771_gene3904	5.477e-76	267.0	COG0765@1|root,COG0765@2|Bacteria,1G2E3@1117|Cyanobacteria,1JK9A@1189|Stigonemataceae	1117|Cyanobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
GDHHQS2_k127_3159781_74	383372.Rcas_1455	3.611e-86	300.0	COG4597@1|root,COG4597@2|Bacteria,2G7PM@200795|Chloroflexi,376AX@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
GDHHQS2_k127_3159781_66	1128421.JAGA01000002_gene1952	7.148e-97	329.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
GDHHQS2_k127_3159781_0	886293.Sinac_4094	0.0	1191.0	COG0178@1|root,COG0178@2|Bacteria,2IYJN@203682|Planctomycetes	203682|Planctomycetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_3159781_215	416348.Hlac_0470	0.0005076	46.0	arCOG08914@1|root,arCOG08914@2157|Archaea,2XZSA@28890|Euryarchaeota,23XNV@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_7	1122221.JHVI01000018_gene1496	9.329e-225	747.0	COG2374@1|root,COG2374@2|Bacteria,1WM95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
GDHHQS2_k127_3159781_54	926569.ANT_05930	1.494e-114	379.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS2_k127_3159781_111	1449126.JQKL01000014_gene2975	2.338e-65	236.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,268Z9@186813|unclassified Clostridiales	186801|Clostridia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS2_k127_3159781_123	926550.CLDAP_30950	1.644e-57	207.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS2_k127_3159781_12	926569.ANT_05900	2.36e-181	575.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_3159781_101	926550.CLDAP_27220	5.661e-74	257.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS2_k127_3159781_148	317936.Nos7107_0764	9.91e-42	168.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G5HD@1117|Cyanobacteria,1HS1K@1161|Nostocales	1117|Cyanobacteria	KT	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AraC,HisKA,Response_reg
GDHHQS2_k127_3159781_103	118163.Ple7327_0723	9.661e-73	258.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5,F5_F8_type_C,Peptidase_S9
GDHHQS2_k127_3159781_210	515622.bpr_I1204	3.845e-05	55.0	COG2755@1|root,COG3401@1|root,COG5263@1|root,COG2755@2|Bacteria,COG3401@2|Bacteria,COG5263@2|Bacteria,1TQR3@1239|Firmicutes,24896@186801|Clostridia,4BWV7@830|Butyrivibrio	186801|Clostridia	E	FG-GAP repeat protein	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	Big_4,CW_binding_1,Dockerin_1,Lipase_GDSL_2,RicinB_lectin_2,SLH
GDHHQS2_k127_3159781_58	485913.Krac_7710	2.963e-108	352.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_3159781_134	485913.Krac_1641	3.735e-53	192.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_3159781_160	1210884.HG799474_gene15133	4.179e-34	149.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
GDHHQS2_k127_3159781_213	1122962.AULH01000012_gene738	0.0003346	53.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,36ZHC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HCBP_related,He_PIG,HemolysinCabind
GDHHQS2_k127_3159781_137	643648.Slip_0153	7.911e-51	198.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,42KJI@68298|Syntrophomonadaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	dltB	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
GDHHQS2_k127_3159781_176	1397528.Q671_14575	4.796e-22	101.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	response regulator	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_3159781_114	521011.Mpal_1101	2.205e-62	219.0	COG0262@1|root,arCOG01490@2157|Archaea,2XXBJ@28890|Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_3159781_170	401053.AciPR4_2074	6.493e-28	127.0	COG1306@1|root,COG1306@2|Bacteria,3Y791@57723|Acidobacteria,2JKV4@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS2_k127_3159781_150	926569.ANT_29540	1.539e-40	160.0	COG0741@1|root,COG0741@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
GDHHQS2_k127_3159781_149	666686.B1NLA3E_12160	2.35e-41	156.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_3159781_31	266117.Rxyl_2670	1.594e-141	485.0	28KNN@1|root,2ZA6V@2|Bacteria,2I2ZK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_180	313612.L8106_05386	1.712e-20	108.0	COG2931@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,1G4A5@1117|Cyanobacteria,1H9XK@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
GDHHQS2_k127_3159781_208	1385512.N784_05310	2.185e-05	57.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4HBN9@91061|Bacilli,2Y8YH@289201|Pontibacillus	91061|Bacilli	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_3159781_49	1183438.GKIL_3646	1.837e-120	403.0	COG1215@1|root,COG1215@2|Bacteria,1G1FP@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GDHHQS2_k127_3159781_85	479434.Sthe_3414	3.687e-81	280.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2,UPF0158
GDHHQS2_k127_3159781_155	1197130.BAFM01000010_gene1848	3.035e-37	150.0	COG2820@1|root,arCOG01324@2157|Archaea,2Y06F@28890|Euryarchaeota,23W2X@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_3159781_139	945713.IALB_2765	8.798e-48	185.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_3159781_8	479434.Sthe_3413	7.033e-224	703.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS2_k127_3159781_138	1123405.AUMM01000027_gene2103	5.764e-49	187.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,4HA1B@91061|Bacilli,26PN3@186821|Sporolactobacillaceae	91061|Bacilli	I	Alpha/beta hydrolase family	yju3	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS2_k127_3159781_191	326427.Cagg_2773	1.914e-14	76.0	28VCT@1|root,2ZHFH@2|Bacteria,2GB88@200795|Chloroflexi,377J8@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3159781_181	1278073.MYSTI_06181	3.521e-20	99.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1N5QD@1224|Proteobacteria,4382E@68525|delta/epsilon subdivisions,2X3CH@28221|Deltaproteobacteria,2YVEM@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_3159781_129	298653.Franean1_4351	2.786e-55	213.0	COG0664@1|root,COG1225@1|root,COG1994@1|root,COG0664@2|Bacteria,COG1225@2|Bacteria,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
GDHHQS2_k127_3159781_204	357808.RoseRS_2661	2.687e-08	58.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS2_k127_3159781_124	675635.Psed_1992	2.321e-57	216.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4EAV1@85010|Pseudonocardiales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_3159781_142	357808.RoseRS_3243	1.217e-45	169.0	COG0757@1|root,COG0757@2|Bacteria,2G6N1@200795|Chloroflexi,3775Y@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GDHHQS2_k127_3159781_76	926550.CLDAP_07310	5.044e-86	297.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GDHHQS2_k127_3159781_166	498761.HM1_0247	1.346e-28	122.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
GDHHQS2_k127_3159781_29	706587.Desti_1327	2.523e-143	467.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MQCX@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
GDHHQS2_k127_3159781_127	926550.CLDAP_13020	3.647e-56	206.0	COG0169@1|root,COG0454@1|root,COG0169@2|Bacteria,COG0456@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
GDHHQS2_k127_3159781_48	404380.Gbem_3258	7.299e-121	403.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,43TXZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS2_k127_3159781_130	926569.ANT_01880	4.012e-55	203.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GDHHQS2_k127_3159781_36	926569.ANT_01870	3.704e-135	437.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS2_k127_3159781_152	1128421.JAGA01000003_gene3433	5.858e-40	151.0	COG4401@1|root,COG4401@2|Bacteria	2|Bacteria	E	Chorismate mutase type I	aroH	GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704	2.7.4.25,5.4.99.5	ko:K00945,ko:K06208	ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230	M00024,M00025,M00052	R00158,R00512,R01665,R01715	RC00002,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GDHHQS2_k127_3159781_92	1047013.AQSP01000131_gene1797	3.633e-77	273.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_3159781_71	65497.JODV01000004_gene1483	5.18e-92	307.0	COG4912@1|root,COG4912@2|Bacteria,2ID3C@201174|Actinobacteria,4E7JU@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS2_k127_3159781_157	1444309.JAQG01000019_gene558	9.055e-37	149.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS2_k127_3159781_214	985255.APHJ01000048_gene409	0.0004174	52.0	2DV5Q@1|root,33U6N@2|Bacteria,4P2AX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3174739_16	1340493.JNIF01000003_gene3428	2.484e-15	78.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_3174739_8	886293.Sinac_4258	1.549e-40	162.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_3174739_1	926550.CLDAP_29890	1.693e-135	441.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
GDHHQS2_k127_3174739_5	485913.Krac_0460	8.427e-57	202.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GDHHQS2_k127_3174739_13	1444309.JAQG01000099_gene4948	1.68e-21	102.0	COG0431@1|root,COG0431@2|Bacteria,1VI8F@1239|Firmicutes,4HPT0@91061|Bacilli,26US4@186822|Paenibacillaceae	91061|Bacilli	S	NADPH-dependent FMN reductase	nqr	-	1.5.1.36,1.7.1.6	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	-	R05705,R09748,R09750	RC00126	ko00000,ko00001,ko01000	-	-	-	FMN_red
GDHHQS2_k127_3174739_2	926569.ANT_06990	5.531e-124	414.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GDHHQS2_k127_3174739_4	926550.CLDAP_05300	1.235e-70	243.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS2_k127_3174739_6	32057.KB217478_gene2589	4.927e-55	201.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HM8C@1161|Nostocales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3174739_3	595460.RRSWK_02314	1.162e-81	280.0	2E0I8@1|root,32W3Z@2|Bacteria,2J0U2@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4343
GDHHQS2_k127_3174739_0	525904.Tter_0098	3.004e-138	453.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
GDHHQS2_k127_3174739_19	118163.Ple7327_0674	2.189e-07	63.0	COG2367@1|root,COG2367@2|Bacteria,1G06I@1117|Cyanobacteria,3VHKW@52604|Pleurocapsales	1117|Cyanobacteria	V	Beta-lactamase enzyme family	ampC	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS2_k127_3174739_22	946235.CAER01000007_gene302	0.000633	51.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,4HNWE@91061|Bacilli	91061|Bacilli	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS2_k127_3174739_18	1382356.JQMP01000004_gene178	1.012e-12	80.0	COG4961@1|root,COG4961@2|Bacteria,2GB9G@200795|Chloroflexi,27YAR@189775|Thermomicrobia	189775|Thermomicrobia	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GDHHQS2_k127_3174739_20	1487923.DP73_09305	5.795e-07	61.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,262WB@186807|Peptococcaceae	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS2_k127_3174739_7	1122603.ATVI01000011_gene2119	1.392e-44	175.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X790@135614|Xanthomonadales	135614|Xanthomonadales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS2_k127_3174739_17	1437425.CSEC_0280	1.459e-13	74.0	COG3237@1|root,COG3237@2|Bacteria,2JHAX@204428|Chlamydiae	204428|Chlamydiae	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_3174739_12	491916.RHECIAT_CH0001889	7.33e-22	96.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,4BGUM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_3174739_11	1286093.C266_20724	6.356e-23	100.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,2VX6M@28216|Betaproteobacteria,1KA9D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cation transport regulator	-	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
GDHHQS2_k127_3174739_15	1499968.TCA2_2819	3.562e-16	80.0	COG3237@1|root,COG3237@2|Bacteria,1VFTC@1239|Firmicutes,4HNXJ@91061|Bacilli,26Z7A@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS2_k127_3174739_14	686340.Metal_3408	9.223e-20	96.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1XGRY@135618|Methylococcales	135618|Methylococcales	S	PFAM ChaB	-	-	-	-	-	-	-	-	-	-	-	-	ChaB
GDHHQS2_k127_3461244_101	1341679.P253_00066	5.069e-06	48.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,3NKN1@468|Moraxellaceae	1236|Gammaproteobacteria	L	Evidence 1 Function experimentally demonstrated in the studied organism	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
GDHHQS2_k127_3461244_70	926569.ANT_28790	3.165e-48	175.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
GDHHQS2_k127_3461244_100	880073.Calab_3462	3.772e-07	53.0	COG1545@1|root,COG1545@2|Bacteria,2NRS7@2323|unclassified Bacteria	2|Bacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	MA20_35595	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
GDHHQS2_k127_3461244_30	926550.CLDAP_27990	5.697e-113	376.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_3461244_18	926569.ANT_28810	8.226e-160	516.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
GDHHQS2_k127_3461244_15	926569.ANT_28820	7.417e-167	535.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
GDHHQS2_k127_3461244_41	926550.CLDAP_18870	6.1e-92	331.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS2_k127_3461244_44	1128421.JAGA01000003_gene2890	1.115e-88	310.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	-	3.6.1.1	ko:K04767,ko:K06213,ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.26.1	-	-	CBS,DHH,DHHA2,DRTGG,MgtE,MgtE_N,PRC
GDHHQS2_k127_3461244_11	926569.ANT_18100	1.181e-188	596.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
GDHHQS2_k127_3461244_49	552398.HMPREF0866_00517	1.489e-82	295.0	COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,249CV@186801|Clostridia,3WND3@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
GDHHQS2_k127_3461244_25	1128421.JAGA01000002_gene1080	2.519e-128	425.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
GDHHQS2_k127_3461244_31	706587.Desti_2994	1.241e-112	373.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,430WX@68525|delta/epsilon subdivisions,2WW1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
GDHHQS2_k127_3461244_61	706587.Desti_2995	7.789e-63	224.0	COG1985@1|root,COG1985@2|Bacteria,1N4VZ@1224|Proteobacteria	1224|Proteobacteria	H	COG1985 Pyrimidine reductase, riboflavin biosynthesis	ribD2	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
GDHHQS2_k127_3461244_56	1134474.O59_002107	2.572e-74	255.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1FHX9@10|Cellvibrio	1236|Gammaproteobacteria	H	GTP cyclohydrolase II	ribA	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2,RibD_C
GDHHQS2_k127_3461244_64	926550.CLDAP_07570	9.899e-57	210.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_3461244_66	926550.CLDAP_07560	6.392e-56	210.0	COG0558@1|root,COG0558@2|Bacteria,2G8YS@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS2_k127_3461244_43	706587.Desti_2991	8.883e-89	301.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
GDHHQS2_k127_3461244_26	926569.ANT_10850	1.866e-127	447.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
GDHHQS2_k127_3461244_14	926569.ANT_12970	1.628e-180	584.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS2_k127_3461244_95	926550.CLDAP_01420	7.929e-10	70.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	-	-	-	-	-	-	-	-	-	-	DUF823,DUF824,LysM,NLPC_P60,SH3_3
GDHHQS2_k127_3461244_52	926569.ANT_10890	2.109e-77	263.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS2_k127_3461244_88	410358.Mlab_0666	1.866e-17	93.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
GDHHQS2_k127_3461244_89	1267535.KB906767_gene2913	2.271e-15	88.0	COG4974@1|root,COG4974@2|Bacteria,3Y73V@57723|Acidobacteria	57723|Acidobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
GDHHQS2_k127_3461244_28	926569.ANT_11650	1.577e-122	405.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
GDHHQS2_k127_3461244_85	926550.CLDAP_22170	1.296e-22	98.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS2_k127_3461244_27	926569.ANT_20510	1.08e-122	403.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_3461244_55	926569.ANT_20520	3.913e-75	267.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS2_k127_3461244_36	525904.Tter_1363	4.421e-98	333.0	COG0635@1|root,COG0635@2|Bacteria,2NP4Y@2323|unclassified Bacteria	2|Bacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS2_k127_3461244_9	926569.ANT_15160	9.931e-199	639.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GDHHQS2_k127_3461244_67	926569.ANT_15150	1.183e-55	206.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS2_k127_3461244_42	926569.ANT_15140	9.737e-91	317.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
GDHHQS2_k127_3461244_82	926569.ANT_15130	1.14e-25	112.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_3461244_92	383372.Rcas_2160	2.105e-14	75.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,375VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_35	926569.ANT_15110	3.754e-100	332.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_3461244_93	1054217.TALC_00512	1.148e-10	67.0	COG1184@1|root,COG1786@1|root,arCOG01127@2157|Archaea,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota	28890|Euryarchaeota	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
GDHHQS2_k127_3461244_7	1128421.JAGA01000002_gene468	2.803e-228	719.0	COG0504@1|root,COG0504@2|Bacteria,2NNVG@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
GDHHQS2_k127_3461244_72	926569.ANT_03760	1.465e-46	171.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GDHHQS2_k127_3461244_39	926569.ANT_09840	4.683e-93	314.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_3461244_97	926569.ANT_09850	2.604e-09	67.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_74	926569.ANT_15370	1.423e-43	176.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS2_k127_3461244_57	264732.Moth_2002	3.85e-72	253.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,42GF3@68295|Thermoanaerobacterales	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
GDHHQS2_k127_3461244_1	926569.ANT_14510	7.806e-314	976.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_3461244_19	926569.ANT_14490	3.053e-158	512.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GDHHQS2_k127_3461244_46	926569.ANT_14480	1.501e-87	297.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS2_k127_3461244_0	926569.ANT_14470	0.0	1252.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GDHHQS2_k127_3461244_91	1172180.KB911779_gene5472	6.814e-15	89.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GDHHQS2_k127_3461244_96	622312.ROSEINA2194_03789	1.909e-09	68.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS2_k127_3461244_79	926569.ANT_25970	5.549e-37	145.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS2_k127_3461244_20	926550.CLDAP_15430	1.537e-156	499.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
GDHHQS2_k127_3461244_84	1382306.JNIM01000001_gene1898	1.548e-23	108.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
GDHHQS2_k127_3461244_38	525904.Tter_1864	2.433e-96	324.0	COG0391@1|root,COG0391@2|Bacteria,2NQGV@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
GDHHQS2_k127_3461244_68	926550.CLDAP_12770	1.994e-54	197.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS2_k127_3461244_53	926569.ANT_14410	3.148e-77	266.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM F420-dependent oxidoreductase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
GDHHQS2_k127_3461244_60	745310.G432_18305	2.185e-67	236.0	COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,2TS1W@28211|Alphaproteobacteria,2K27G@204457|Sphingomonadales	204457|Sphingomonadales	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS2_k127_3461244_17	926569.ANT_14390	7.711e-164	527.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS2_k127_3461244_81	926569.ANT_04640	9.187e-30	126.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_13	1304874.JAFY01000007_gene2147	1.157e-184	587.0	COG0031@1|root,COG0031@2|Bacteria,3T9XD@508458|Synergistetes	508458|Synergistetes	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
GDHHQS2_k127_3461244_24	926569.ANT_04660	2.059e-133	432.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GDHHQS2_k127_3461244_3	1499967.BAYZ01000089_gene5053	1.73e-255	806.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
GDHHQS2_k127_3461244_21	1167006.UWK_01323	5.538e-150	485.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_3461244_47	864702.OsccyDRAFT_3865	1.359e-84	291.0	COG1079@1|root,COG1079@2|Bacteria,1GCKW@1117|Cyanobacteria,1HEF9@1150|Oscillatoriales	1117|Cyanobacteria	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_3461244_63	864702.OsccyDRAFT_1416	6.223e-60	220.0	COG4603@1|root,COG4603@2|Bacteria	2|Bacteria	L	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_3461244_29	864702.OsccyDRAFT_1800	1.786e-122	411.0	COG3845@1|root,COG3845@2|Bacteria,1G4UA@1117|Cyanobacteria,1HH79@1150|Oscillatoriales	1117|Cyanobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS2_k127_3461244_23	643562.Daes_2684	1.689e-134	440.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,42NPH@68525|delta/epsilon subdivisions,2WIXM@28221|Deltaproteobacteria,2MG14@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Basic membrane lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
GDHHQS2_k127_3461244_16	926550.CLDAP_10970	7.265e-164	520.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS2_k127_3461244_12	926569.ANT_01240	6.114e-186	588.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_3461244_8	926550.CLDAP_18550	3.639e-216	684.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
GDHHQS2_k127_3461244_37	264732.Moth_1997	1.347e-96	332.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,42FU6@68295|Thermoanaerobacterales	186801|Clostridia	F	Amidohydrolase family	hydA	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GDHHQS2_k127_3461244_10	1005048.CFU_3458	4.497e-189	602.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,475WE@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Amidohydrolase family	atzB	-	3.5.4.32	ko:K18456	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_3461244_34	13333.ERN02178	6.305e-103	343.0	COG0190@1|root,KOG0089@2759|Eukaryota,37K6Z@33090|Viridiplantae,3GCGD@35493|Streptophyta	35493|Streptophyta	H	Bifunctional protein FolD	-	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019219,GO:0019222,GO:0019238,GO:0019752,GO:0031323,GO:0034641,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044030,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046653,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051186,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS2_k127_3461244_69	326427.Cagg_3160	6.172e-54	201.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi,376U0@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
GDHHQS2_k127_3461244_75	1121468.AUBR01000023_gene2722	6.458e-41	157.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GEY@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
GDHHQS2_k127_3461244_78	443598.AUFA01000013_gene6558	2.363e-38	147.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,3JYW0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
GDHHQS2_k127_3461244_22	926550.CLDAP_04540	4.867e-135	445.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS2_k127_3461244_45	326427.Cagg_1652	3.331e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_3461244_4	926550.CLDAP_13490	1.076e-243	779.0	COG1205@1|root,COG1403@1|root,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
GDHHQS2_k127_3461244_77	313596.RB2501_12022	2.346e-38	159.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_3461244_76	1385517.N800_12715	3.554e-39	149.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SE7M@1236|Gammaproteobacteria,1XC6D@135614|Xanthomonadales	135614|Xanthomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_32	518766.Rmar_1923	1.727e-111	370.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GDHHQS2_k127_3461244_83	215803.DB30_5213	3.293e-25	120.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2XA07@28221|Deltaproteobacteria,2YZHM@29|Myxococcales	28221|Deltaproteobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PKD
GDHHQS2_k127_3461244_54	926569.ANT_24890	1.737e-76	271.0	COG0707@1|root,COG0707@2|Bacteria,2G8GF@200795|Chloroflexi	200795|Chloroflexi	M	Monogalactosyldiacylglycerol synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,MGDG_synth
GDHHQS2_k127_3461244_6	926569.ANT_28860	1.086e-228	735.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS2_k127_3461244_98	290340.AAur_0548	1.788e-07	62.0	COG2197@1|root,COG2197@2|Bacteria,2IJWD@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_3461244_71	1267535.KB906767_gene3028	9.855e-47	181.0	COG2843@1|root,COG2843@2|Bacteria,3Y8HU@57723|Acidobacteria	57723|Acidobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
GDHHQS2_k127_3461244_5	867845.KI911784_gene100	3.797e-231	725.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,3751K@32061|Chloroflexia	32061|Chloroflexia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS2_k127_3461244_87	926569.ANT_17320	8.698e-18	93.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_59	1499967.BAYZ01000090_gene4936	1.793e-68	245.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_3461244_50	525904.Tter_0795	2.648e-80	273.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_3461244_58	926569.ANT_22650	4.075e-71	258.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_3461244_103	335541.Swol_2259	6.235e-05	51.0	COG3339@1|root,COG3339@2|Bacteria,1V6NW@1239|Firmicutes,25D8Z@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS2_k127_3461244_90	1128421.JAGA01000002_gene1422	2.874e-15	87.0	2E7PW@1|root,3325F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_2	926569.ANT_04370	1.973e-273	854.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS2_k127_3461244_51	243090.RB10757	1.961e-77	295.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,Guanylate_cyc
GDHHQS2_k127_3461244_33	118163.Ple7327_0740	1.88e-111	391.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,3VM91@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_3461244_106	379731.PST_3560	0.000393	48.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T9CR@1236|Gammaproteobacteria,1Z2CD@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_4,Response_reg
GDHHQS2_k127_3461244_62	1173026.Glo7428_2204	1.691e-61	215.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_3461244_40	1173026.Glo7428_2205	5.227e-93	330.0	COG2203@1|root,COG3300@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3300@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_3461244_48	926569.ANT_31200	1.068e-82	308.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_3461244_80	1162668.LFE_2304	2.856e-32	147.0	COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Bac_transf,GAF,PAS_3,PAS_4,PAS_9,Response_reg,TPR_8
GDHHQS2_k127_3461244_73	926550.CLDAP_31390	1.921e-44	185.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3461244_65	525904.Tter_0641	2.345e-56	222.0	COG2197@1|root,COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2NR2Y@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	ydfH	-	2.7.13.3	ko:K02479,ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GerE,HATPase_c,HisKA,HisKA_3,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_3461244_104	349161.Dred_0788	0.0001067	52.0	COG4974@1|root,COG4974@2|Bacteria,1V1FM@1239|Firmicutes,24H96@186801|Clostridia,2629E@186807|Peptococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
GDHHQS2_k127_3461244_107	1218076.BAYB01000007_gene1375	0.0009133	46.0	COG1476@1|root,COG1476@2|Bacteria,1NAGK@1224|Proteobacteria,2VWAT@28216|Betaproteobacteria,1KA7D@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS2_k127_3461244_105	1278309.KB907100_gene2283	0.0003037	54.0	2A118@1|root,30P6R@2|Bacteria,1REVJ@1224|Proteobacteria,1SY8N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
GDHHQS2_k127_3461244_94	313612.L8106_29985	2.226e-10	66.0	COG2842@1|root,COG2842@2|Bacteria,1GB1T@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
GDHHQS2_k127_367527_57	575588.ACPN01000124_gene1909	3.026e-07	51.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_367527_15	1107311.Q767_15140	8.199e-70	238.0	298UU@1|root,2ZVYZ@2|Bacteria,4NPH1@976|Bacteroidetes,1I8RV@117743|Flavobacteriia,2NWGH@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_367527_7	485913.Krac_6314	5.232e-137	439.0	COG0491@1|root,COG0491@2|Bacteria,2G7MM@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GDHHQS2_k127_367527_39	1206741.BAFX01000146_gene2906	1.717e-32	133.0	2BBAF@1|root,324T6@2|Bacteria,2IM1Z@201174|Actinobacteria,4G0YD@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_20	103690.17131306	1.72e-64	239.0	COG0477@1|root,COG2814@2|Bacteria,1G1MW@1117|Cyanobacteria,1HM0N@1161|Nostocales	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_367527_3	926569.ANT_09690	5.504e-159	508.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS2_k127_367527_19	357808.RoseRS_2229	3.532e-66	252.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_367527_18	357808.RoseRS_2229	7.773e-67	253.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_367527_44	646529.Desaci_0681	7.355e-29	124.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_367527_58	1343740.M271_25860	4.661e-06	55.0	2BTC8@1|root,32NI0@2|Bacteria,2IPGR@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_46	331678.Cphamn1_0275	1.151e-21	102.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_367527_42	646529.Desaci_0681	4.063e-30	126.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_367527_48	1313421.JHBV01000008_gene4331	1.261e-12	72.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS2_k127_367527_5	1242864.D187_001830	5.33e-140	491.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_367527_22	1382306.JNIM01000001_gene1873	5.043e-59	235.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GDHHQS2_k127_367527_54	504472.Slin_6155	8.66e-08	62.0	2B7JP@1|root,320QE@2|Bacteria,4NZGU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_8	1132855.KB913035_gene143	3.084e-130	424.0	28MDK@1|root,2ZARD@2|Bacteria,1R47P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_37	1120959.ATXF01000005_gene958	4.925e-34	135.0	2DMMA@1|root,32SDH@2|Bacteria,2HZ6N@201174|Actinobacteria,4FSGP@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_11	316274.Haur_2917	1.137e-86	300.0	COG4805@1|root,COG4805@2|Bacteria,2G8D3@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_52	7918.ENSLOCP00000018594	3.74e-08	66.0	COG0457@1|root,KOG1124@2759|Eukaryota,38F8U@33154|Opisthokonta,3BAQE@33208|Metazoa,3CV5D@33213|Bilateria,4828P@7711|Chordata,4912M@7742|Vertebrata,49RN3@7898|Actinopterygii	33208|Metazoa	S	Transmembrane and	TMTC1	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GDHHQS2_k127_367527_32	316274.Haur_3458	2.879e-41	173.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
GDHHQS2_k127_367527_60	1142394.PSMK_19610	2.75e-05	56.0	COG1216@1|root,COG1216@2|Bacteria,2IZFD@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_367527_6	1382306.JNIM01000001_gene1569	6.467e-138	451.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_367527_17	1382306.JNIM01000001_gene514	6.623e-67	252.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
GDHHQS2_k127_367527_16	266117.Rxyl_1220	2.864e-67	233.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria	201174|Actinobacteria	V	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS2_k127_367527_38	926550.CLDAP_00400	4.17e-33	135.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS2_k127_367527_51	357808.RoseRS_4388	1.382e-10	72.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_367527_26	326427.Cagg_2227	1.168e-54	200.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_367527_9	153721.MYP_431	4.535e-115	377.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,47MHX@768503|Cytophagia	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS2_k127_367527_29	671143.DAMO_0398	1.274e-47	177.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	iscA	-	-	ko:K07400,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn,Nfu_N,NifU
GDHHQS2_k127_367527_24	926569.ANT_21000	2.232e-55	196.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GDHHQS2_k127_367527_25	926569.ANT_21000	3.231e-55	196.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GDHHQS2_k127_367527_61	32057.KB217478_gene3006	7.818e-05	50.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_367527_21	861299.J421_3591	2.799e-60	216.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS2_k127_367527_12	926550.CLDAP_27640	1.739e-82	280.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_367527_56	192952.MM_2350	1.327e-07	64.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota	28890|Euryarchaeota	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
GDHHQS2_k127_367527_14	661478.OP10G_2200	1.443e-72	260.0	2DQGC@1|root,336PP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
GDHHQS2_k127_367527_10	926569.ANT_18600	4.79e-105	350.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GDHHQS2_k127_367527_47	1040982.AXAL01000031_gene657	2.028e-17	97.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
GDHHQS2_k127_367527_33	690850.Desaf_2817	2.211e-40	155.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,2MCM3@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_367527_1	448385.sce7039	7.56e-195	622.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YX8I@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
GDHHQS2_k127_367527_50	926569.ANT_15990	1.032e-10	70.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS2_k127_367527_0	215803.DB30_4872	2.559e-215	685.0	COG3864@1|root,COG3864@2|Bacteria	2|Bacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
GDHHQS2_k127_367527_2	272123.Anacy_1200	4.153e-172	545.0	COG0714@1|root,COG0714@2|Bacteria,1GD74@1117|Cyanobacteria,1HQHU@1161|Nostocales	1117|Cyanobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GDHHQS2_k127_367527_43	401526.TcarDRAFT_0760	1.634e-29	134.0	COG4636@1|root,COG4636@2|Bacteria,1V46Z@1239|Firmicutes	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox,Uma2
GDHHQS2_k127_367527_4	926569.ANT_08710	2.062e-151	503.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS2_k127_367527_35	997296.PB1_02415	3.155e-38	151.0	COG1309@1|root,COG1309@2|Bacteria,1VRIJ@1239|Firmicutes,4HUEE@91061|Bacilli,1ZGXC@1386|Bacillus	91061|Bacilli	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
GDHHQS2_k127_367527_13	1329516.JPST01000006_gene1630	2.037e-77	265.0	COG0500@1|root,COG2226@2|Bacteria,1V7UE@1239|Firmicutes,4HIXI@91061|Bacilli,27CJV@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_367527_30	1321781.HMPREF1985_02121	8.604e-44	165.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4H2M3@909932|Negativicutes	909932|Negativicutes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS2_k127_367527_40	756067.MicvaDRAFT_1417	3.223e-32	131.0	COG3502@1|root,COG3502@2|Bacteria,1G99N@1117|Cyanobacteria,1HBZI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF952)	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
GDHHQS2_k127_367527_36	290315.Clim_1904	1.971e-37	144.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_367527_28	926569.ANT_07430	1.193e-49	191.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS2_k127_367527_34	383372.Rcas_4353	1.099e-38	148.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GDHHQS2_k127_367527_45	926569.ANT_28160	7.069e-28	119.0	COG0622@1|root,COG0622@2|Bacteria,2G7DJ@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
GDHHQS2_k127_367527_31	1121123.AUAO01000003_gene2023	2.245e-42	177.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	yidC	-	-	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas
GDHHQS2_k127_367527_23	357808.RoseRS_2229	1.647e-57	226.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_367527_49	316274.Haur_1614	7.932e-11	74.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
GDHHQS2_k127_367527_27	926569.ANT_29790	6.086e-53	196.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS2_k127_3772698_30	886293.Sinac_5547	7.233e-30	119.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,2IYN8@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS2_k127_3772698_17	926569.ANT_18220	2.84e-71	246.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS2_k127_3772698_32	926569.ANT_18210	7.038e-29	121.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3772698_7	926569.ANT_18200	1.084e-129	423.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS2_k127_3772698_15	1267535.KB906767_gene4720	7.507e-90	316.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
GDHHQS2_k127_3772698_23	331869.BAL199_05609	1.342e-43	173.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_3772698_2	1173027.Mic7113_4161	1.564e-185	612.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_3772698_21	794903.OPIT5_07180	8.576e-55	194.0	COG0745@1|root,COG0745@2|Bacteria,46VXW@74201|Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_3772698_46	485913.Krac_9360	0.0004585	44.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
GDHHQS2_k127_3772698_9	485913.Krac_9361	3.248e-117	383.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS2_k127_3772698_18	1382306.JNIM01000001_gene2430	3.923e-64	228.0	COG2186@1|root,COG2186@2|Bacteria,2G959@200795|Chloroflexi	200795|Chloroflexi	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS2_k127_3772698_5	1254432.SCE1572_20250	2.906e-141	462.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3772698_11	1254432.SCE1572_20250	7.543e-104	345.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3772698_8	1254432.SCE1572_20255	2.941e-118	389.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,42TEH@68525|delta/epsilon subdivisions,2WPV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_3772698_12	1254432.SCE1572_20260	6.313e-101	334.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS2_k127_3772698_16	1254432.SCE1572_20265	1.215e-88	299.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS2_k127_3772698_13	383372.Rcas_4287	8.048e-95	331.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,375AD@32061|Chloroflexia	32061|Chloroflexia	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GDHHQS2_k127_3772698_1	926550.CLDAP_02810	2.36e-203	649.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS2_k127_3772698_26	926560.KE387023_gene2482	6.651e-36	139.0	arCOG11507@1|root,333W5@2|Bacteria,1WN09@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3772698_10	240292.Ava_C0001	1.481e-113	381.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1HKQS@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_3772698_6	926560.KE387023_gene2481	1.178e-136	443.0	COG0667@1|root,COG0667@2|Bacteria,1WM4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_3772698_14	765420.OSCT_1132	2.778e-93	314.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS2_k127_3772698_35	926550.CLDAP_23490	2.604e-22	114.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS2_k127_3772698_4	1120973.AQXL01000115_gene665	8.087e-155	498.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,2785J@186823|Alicyclobacillaceae	91061|Bacilli	P	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
GDHHQS2_k127_3772698_3	886293.Sinac_5883	5.98e-161	520.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_3772698_45	1089439.KB902251_gene1515	2.997e-05	47.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3772698_47	103690.17130280	0.0006817	46.0	COG0270@1|root,COG0270@2|Bacteria,1G3T5@1117|Cyanobacteria,1HMCH@1161|Nostocales	1117|Cyanobacteria	L	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_17,MerR
GDHHQS2_k127_3772698_37	1121861.KB899911_gene1307	2.153e-15	91.0	COG3598@1|root,COG3598@2|Bacteria,1QZRH@1224|Proteobacteria,2TYCX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Bifunctional DNA primase/polymerase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Prim-Pol
GDHHQS2_k127_3772698_33	697281.Mahau_2392	1.929e-25	119.0	COG0443@1|root,COG0443@2|Bacteria,1V76M@1239|Firmicutes,24GMR@186801|Clostridia,42G24@68295|Thermoanaerobacterales	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
GDHHQS2_k127_3772698_22	1120949.KB903312_gene582	1.03e-45	175.0	2C08P@1|root,2ZC0W@2|Bacteria,2GVVA@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4417)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4417
GDHHQS2_k127_3772698_34	1304883.KI912532_gene2645	6.845e-25	117.0	COG0610@1|root,COG0610@2|Bacteria,1NHED@1224|Proteobacteria	1224|Proteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3772698_27	1347086.CCBA010000039_gene4931	2.129e-34	137.0	COG2110@1|root,COG2110@2|Bacteria,1UY8V@1239|Firmicutes,4HD2D@91061|Bacilli,1ZIP1@1386|Bacillus	91061|Bacilli	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
GDHHQS2_k127_3772698_19	498848.TaqDRAFT_3009	3.773e-60	240.0	COG0553@1|root,COG0553@2|Bacteria,1WKWF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
GDHHQS2_k127_3772698_24	926569.ANT_20730	8.564e-40	173.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS2_k127_3772698_40	1370120.AUWR01000058_gene2440	5.289e-13	79.0	COG5519@1|root,COG5519@2|Bacteria,2I7XJ@201174|Actinobacteria,23C0Q@1762|Mycobacteriaceae	201174|Actinobacteria	L	Bifunctional DNA primase/polymerase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Prim-Pol
GDHHQS2_k127_3772698_38	927677.ALVU02000002_gene308	3.84e-14	83.0	2E1Q3@1|root,32X0G@2|Bacteria,1G8H6@1117|Cyanobacteria	1117|Cyanobacteria	S	Prokaryotic E2 family D	-	-	-	-	-	-	-	-	-	-	-	-	Prok-E2_D
GDHHQS2_k127_3772698_28	56107.Cylst_6377	1.111e-33	139.0	COG0476@1|root,COG0476@2|Bacteria,1G114@1117|Cyanobacteria,1HKKA@1161|Nostocales	1117|Cyanobacteria	H	COGs COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
GDHHQS2_k127_3772698_20	383372.Rcas_2606	4.816e-55	203.0	COG1409@1|root,COG1409@2|Bacteria,2G9SB@200795|Chloroflexi	200795|Chloroflexi	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_3772698_25	926550.CLDAP_14930	4.061e-39	149.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS2_k127_3772698_31	525904.Tter_0463	3.375e-29	122.0	COG0071@1|root,COG0071@2|Bacteria,2NPXZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS2_k127_3772698_43	342610.Patl_4154	1.105e-06	51.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2Q1FS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_3,PAS_4
GDHHQS2_k127_3772698_36	479434.Sthe_0924	6.24e-21	102.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi,27Y25@189775|Thermomicrobia	189775|Thermomicrobia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	-	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_3772698_29	479434.Sthe_2045	5.915e-33	143.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
GDHHQS2_k127_3772698_44	552811.Dehly_0427	7.312e-06	51.0	29U2R@1|root,30FC1@2|Bacteria,2G9M3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3772698_0	479434.Sthe_0227	2.025e-260	837.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GDHHQS2_k127_3859282_0	926550.CLDAP_23750	2.013e-174	559.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
GDHHQS2_k127_3859282_32	1423321.AS29_04105	1.381e-10	73.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
GDHHQS2_k127_3859282_22	455632.SGR_1454	3.723e-37	148.0	COG2968@1|root,COG2968@2|Bacteria,2HYDA@201174|Actinobacteria,41CGR@629295|Streptomyces griseus group	201174|Actinobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS2_k127_3859282_5	1382356.JQMP01000001_gene952	9.017e-132	430.0	COG0346@1|root,COG0346@2|Bacteria,2G7JF@200795|Chloroflexi,27YAW@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_3859282_26	479434.Sthe_2503	1.21e-32	133.0	COG1853@1|root,COG1853@2|Bacteria,2G9BM@200795|Chloroflexi,27Z20@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS2_k127_3859282_1	1382356.JQMP01000001_gene950	7.545e-173	554.0	COG2368@1|root,COG2368@2|Bacteria,2GAH7@200795|Chloroflexi,27XER@189775|Thermomicrobia	189775|Thermomicrobia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
GDHHQS2_k127_3859282_35	1449126.JQKL01000005_gene933	6.938e-07	56.0	COG0399@1|root,COG0399@2|Bacteria,1VGIE@1239|Firmicutes,24PJD@186801|Clostridia	186801|Clostridia	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_3859282_36	926690.KE386573_gene1029	9.79e-05	51.0	arCOG02898@1|root,arCOG02898@2157|Archaea,2XZ0V@28890|Euryarchaeota,23WT3@183963|Halobacteria	183963|Halobacteria	S	Polyketide cyclase / dehydrase and lipid transport	blp	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_3859282_17	383372.Rcas_1243	9.032e-51	183.0	COG2346@1|root,COG2346@2|Bacteria,2G9T7@200795|Chloroflexi,377F9@32061|Chloroflexia	32061|Chloroflexia	S	PFAM globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS2_k127_3859282_16	1121468.AUBR01000010_gene2422	1.642e-54	195.0	COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,24HFR@186801|Clostridia,42IAH@68295|Thermoanaerobacterales	186801|Clostridia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
GDHHQS2_k127_3859282_3	316274.Haur_0522	6.029e-138	451.0	COG0183@1|root,COG0183@2|Bacteria,2G66E@200795|Chloroflexi,3753E@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_3859282_14	1510531.JQJJ01000010_gene2147	1.778e-58	205.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2U9J3@28211|Alphaproteobacteria,3JY2B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_3859282_18	1122222.AXWR01000002_gene2059	1.776e-48	179.0	COG0666@1|root,COG0666@2|Bacteria,1WN2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3859282_29	1385514.N782_11565	1.355e-26	113.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,2YAMX@289201|Pontibacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_3859282_11	1405.DJ92_414	9.458e-77	268.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07471,ko:K13652,ko:K19056	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,DinB_2,GyrI-like,HTH_18
GDHHQS2_k127_3859282_20	1415780.JPOG01000001_gene2299	1.737e-39	168.0	COG3011@1|root,COG3011@2|Bacteria,1NP8B@1224|Proteobacteria,1RZ0C@1236|Gammaproteobacteria,1X5DK@135614|Xanthomonadales	135614|Xanthomonadales	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
GDHHQS2_k127_3859282_27	926569.ANT_29030	1.636e-30	121.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
GDHHQS2_k127_3859282_15	926569.ANT_28890	9.055e-56	207.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_3859282_30	1194972.MVAC_07451	1.913e-21	110.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,2I5NY@201174|Actinobacteria,236BA@1762|Mycobacteriaceae	201174|Actinobacteria	KT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Guanylate_cyc,Response_reg
GDHHQS2_k127_3859282_23	1128421.JAGA01000002_gene1672	4.535e-37	160.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	1128421.JAGA01000002_gene1672|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3859282_19	926569.ANT_11830	4.968e-46	177.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
GDHHQS2_k127_3859282_10	357808.RoseRS_2743	8.675e-77	267.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi,375N7@32061|Chloroflexia	32061|Chloroflexia	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS2_k127_3859282_7	1192034.CAP_3990	1.795e-113	374.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_3859282_12	330214.NIDE1434	6.841e-67	236.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_3859282_34	65093.PCC7418_3031	6.241e-07	59.0	COG1716@1|root,COG1716@2|Bacteria,1FZW5@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM FHA domain	fraH	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GDHHQS2_k127_3859282_4	1121380.JNIW01000013_gene2045	3.992e-137	447.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_3859282_37	1040986.ATYO01000004_gene4826	0.0005093	50.0	COG1595@1|root,COG1595@2|Bacteria,1R96P@1224|Proteobacteria,2VF9J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GDHHQS2_k127_3859282_6	1089550.ATTH01000001_gene2174	1.737e-113	373.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1FJXN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS2_k127_3859282_2	926569.ANT_13120	1.803e-155	509.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS2_k127_3859282_33	266940.Krad_1063	7.156e-09	69.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
GDHHQS2_k127_3859282_25	335541.Swol_1996	5.546e-35	156.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
GDHHQS2_k127_3859282_24	1391646.AVSU01000054_gene1174	1.682e-35	145.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,25RB0@186804|Peptostreptococcaceae	186801|Clostridia	H	thiamine	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
GDHHQS2_k127_3859282_8	485913.Krac_2372	8.738e-110	367.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_3859282_21	1469607.KK073768_gene435	1.149e-37	144.0	COG2852@1|root,COG2852@2|Bacteria,1GNS3@1117|Cyanobacteria,1HP42@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS2_k127_3859282_31	1121930.AQXG01000001_gene1488	1.211e-18	98.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
GDHHQS2_k127_3859282_13	1121428.DESHY_30067___1	7.647e-66	234.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,261JQ@186807|Peptococcaceae	186801|Clostridia	U	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS2_k127_3859282_28	981383.AEWH01000068_gene344	7.472e-29	130.0	COG0454@1|root,COG0456@2|Bacteria,1TU2N@1239|Firmicutes,4HH34@91061|Bacilli	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_4
GDHHQS2_k127_3859282_9	935836.JAEL01000023_gene1588	7.758e-103	344.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	M1-596	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_3933_0	330214.NIDE3454	2.448e-74	269.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
GDHHQS2_k127_4075252_0	383372.Rcas_1705	1.453e-70	247.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_4075252_4	530564.Psta_2511	7.635e-12	68.0	COG3070@1|root,33F6F@2|Bacteria	2|Bacteria	K	TfoX C-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C
GDHHQS2_k127_4075252_3	243090.RB289	1.093e-56	207.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_4075252_2	266117.Rxyl_2316	9.438e-64	223.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4CU5I@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_4075252_1	32057.KB217480_gene8206	6.729e-68	235.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_4078167_16	926569.ANT_03360	3.543e-87	295.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
GDHHQS2_k127_4078167_3	357808.RoseRS_3079	4.7e-150	488.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,37577@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
GDHHQS2_k127_4078167_9	1128421.JAGA01000003_gene2975	3.217e-121	399.0	COG0136@1|root,COG0136@2|Bacteria,2NNU7@2323|unclassified Bacteria	2|Bacteria	E	Semialdehyde dehydrogenase, NAD binding domain	asd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.2.1.11,1.2.1.12	ko:K00133,ko:K00134	ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010	M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552	R01061,R02291	RC00149,RC00684	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N,Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_4078167_55	391625.PPSIR1_35507	1.866e-05	48.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_4078167_37	383372.Rcas_3360	1.633e-33	136.0	COG1246@1|root,COG1246@2|Bacteria,2G924@200795|Chloroflexi,377Z1@32061|Chloroflexia	32061|Chloroflexia	E	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GDHHQS2_k127_4078167_7	357808.RoseRS_0842	1.01e-127	421.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi,3758Z@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_4078167_29	357808.RoseRS_4053	4.149e-60	217.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi,375PI@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_4078167_14	316274.Haur_4144	6.255e-94	320.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,3759I@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS2_k127_4078167_1	1128421.JAGA01000001_gene2134	1.253e-222	720.0	COG2352@1|root,COG2352@2|Bacteria,2NQRN@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxylase	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ppc	PEPcase
GDHHQS2_k127_4078167_41	635013.TherJR_2315	3.294e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,26736@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4078167_24	1382359.JIAL01000001_gene1447	5.999e-70	254.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria,2JHY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_4078167_47	1123508.JH636440_gene2897	3.406e-10	62.0	2EV93@1|root,33NPS@2|Bacteria,2J4Q3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_46	575540.Isop_3685	2.023e-11	65.0	2EV93@1|root,33NPS@2|Bacteria,2J4Q3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_45	1121403.AUCV01000069_gene2311	2.993e-12	67.0	2EV93@1|root,33NPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_36	575540.Isop_3677	1.233e-33	134.0	COG0745@1|root,COG0745@2|Bacteria,2J342@203682|Planctomycetes	203682|Planctomycetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_4078167_42	575540.Isop_3688	3.407e-15	83.0	COG0457@1|root,COG0835@1|root,COG0457@2|Bacteria,COG0835@2|Bacteria,2J076@203682|Planctomycetes	203682|Planctomycetes	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_4078167_32	1121403.AUCV01000069_gene2310	3.122e-47	190.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
GDHHQS2_k127_4078167_5	522306.CAP2UW1_3590	5.22e-138	471.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
GDHHQS2_k127_4078167_56	1219045.BV98_001754	6.608e-05	51.0	COG0835@1|root,COG0835@2|Bacteria,1N88R@1224|Proteobacteria,2UGI7@28211|Alphaproteobacteria,2K55G@204457|Sphingomonadales	204457|Sphingomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS2_k127_4078167_17	926569.ANT_11070	5.422e-87	298.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GDHHQS2_k127_4078167_0	326427.Cagg_1691	1.116e-268	855.0	COG1361@1|root,COG1472@1|root,COG1361@2|Bacteria,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
GDHHQS2_k127_4078167_10	926550.CLDAP_24490	2.665e-111	371.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS2_k127_4078167_21	926550.CLDAP_13300	1.332e-77	271.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
GDHHQS2_k127_4078167_8	324602.Caur_1078	1.724e-123	412.0	COG1653@1|root,COG1653@2|Bacteria,2G7RQ@200795|Chloroflexi,377M8@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
GDHHQS2_k127_4078167_18	926550.CLDAP_13320	2.059e-86	297.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_4078167_11	485913.Krac_0278	3.309e-111	368.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS2_k127_4078167_49	313628.LNTAR_00800	2.141e-08	57.0	COG0745@1|root,COG0745@2|Bacteria	313628.LNTAR_00800|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_19	1499967.BAYZ01000085_gene5180	1.545e-79	280.0	COG0438@1|root,COG0438@2|Bacteria,2NRDY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	tuaC	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K16697	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	iYO844.BSU35590	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4078167_34	1220534.B655_0767	4.355e-36	151.0	COG0438@1|root,arCOG01403@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4078167_31	1499967.BAYZ01000086_gene5149	2.234e-52	200.0	COG0438@1|root,COG0438@2|Bacteria,2NR76@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4078167_35	749222.Nitsa_1713	9.152e-35	136.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2YT5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS2_k127_4078167_44	186497.PF1630	1.189e-12	70.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,24369@183968|Thermococci	183968|Thermococci	M	UDP-n-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS2_k127_4078167_20	760568.Desku_1745	2.438e-79	281.0	COG0438@1|root,COG0438@2|Bacteria,1V5W1@1239|Firmicutes,24HV6@186801|Clostridia,263ZC@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GDHHQS2_k127_4078167_23	395495.Lcho_0971	1.502e-71	253.0	COG2227@1|root,COG2227@2|Bacteria,1PFR3@1224|Proteobacteria,2W9ZJ@28216|Betaproteobacteria,1KP3V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS2_k127_4078167_54	204773.HEAR1129	1.677e-05	57.0	COG2244@1|root,COG2244@2|Bacteria,1RCHB@1224|Proteobacteria,2W10D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_28	1499967.BAYZ01000085_gene5179	3.836e-62	228.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4078167_26	56110.Oscil6304_3545	4.656e-63	230.0	COG0438@1|root,COG0438@2|Bacteria,1G40J@1117|Cyanobacteria,1H9VA@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4078167_40	1396141.BATP01000060_gene4737	1.374e-21	98.0	COG0664@1|root,COG0664@2|Bacteria,46X6S@74201|Verrucomicrobia,2IURE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS2_k127_4078167_53	118161.KB235922_gene1640	5.032e-06	60.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1G2HS@1117|Cyanobacteria,3VKW9@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_4078167_52	102125.Xen7305DRAFT_00024820	7.262e-07	63.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1G2HS@1117|Cyanobacteria,3VKW9@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS2_k127_4078167_27	309801.trd_0688	8.844e-63	225.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
GDHHQS2_k127_4078167_25	926569.ANT_09460	1.261e-63	235.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS2_k127_4078167_13	316274.Haur_0023	9.365e-98	339.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_4078167_51	867845.KI911784_gene1883	5.857e-07	58.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
GDHHQS2_k127_4078167_6	1528106.JRJE01000031_gene3231	2.788e-132	439.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,2TQY1@28211|Alphaproteobacteria,2JT22@204441|Rhodospirillales	204441|Rhodospirillales	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
GDHHQS2_k127_4078167_30	1206733.BAGC01000042_gene2191	1.128e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4078167_50	436229.JOEH01000014_gene6103	5.826e-07	61.0	COG0596@1|root,COG0596@2|Bacteria,2I8EU@201174|Actinobacteria,2NM8N@228398|Streptacidiphilus	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_4078167_12	926569.ANT_25700	1.41e-109	377.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_4078167_43	42256.RradSPS_1627	1.665e-13	77.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CPMC@84995|Rubrobacteria	84995|Rubrobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS2_k127_4078167_4	661478.OP10G_2436	4.116e-140	454.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_4078167_38	1122599.AUGR01000037_gene936	2.697e-32	138.0	COG2865@1|root,COG2865@2|Bacteria,1R611@1224|Proteobacteria,1S0MT@1236|Gammaproteobacteria,1XNKS@135619|Oceanospirillales	135619|Oceanospirillales	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
GDHHQS2_k127_4078167_2	1123367.C666_09185	2.803e-171	552.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,2KV56@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS2_k127_4078167_48	1173263.Syn7502_00051	7.617e-09	62.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,1G2QW@1117|Cyanobacteria,1H1J5@1129|Synechococcus	1117|Cyanobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
GDHHQS2_k127_4078167_15	926569.ANT_27790	1.323e-89	305.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_4078167_57	207559.Dde_1156	7.672e-05	54.0	2AN1N@1|root,31CZ2@2|Bacteria,1Q9Z8@1224|Proteobacteria,4366W@68525|delta/epsilon subdivisions,2X0R5@28221|Deltaproteobacteria,2MD68@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4078167_59	1223545.GS4_05_01320	0.0009931	50.0	COG0789@1|root,COG0789@2|Bacteria,2INNF@201174|Actinobacteria	201174|Actinobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
GDHHQS2_k127_4078167_33	926550.CLDAP_14870	2.276e-42	159.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS2_k127_4078167_58	620914.JH621294_gene3415	0.0004185	44.0	COG1028@1|root,COG1028@2|Bacteria,4NTIN@976|Bacteroidetes,1IIVH@117743|Flavobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_4078167_22	926569.ANT_09760	1.838e-76	270.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_4175217_5	926550.CLDAP_17580	3.862e-88	315.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS2_k127_4175217_10	545243.BAEV01000019_gene2125	7.127e-54	191.0	COG4817@1|root,COG4817@2|Bacteria,1V3TW@1239|Firmicutes,24HFX@186801|Clostridia,36J2X@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1048)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1048
GDHHQS2_k127_4175217_8	1449063.JMLS01000045_gene6341	1.157e-59	207.0	COG4817@1|root,COG4817@2|Bacteria,1V9TF@1239|Firmicutes,4HICW@91061|Bacilli,26XMF@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1048)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1048
GDHHQS2_k127_4175217_9	913865.DOT_1199	1.44e-56	200.0	COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,24MZ2@186801|Clostridia,262HC@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
GDHHQS2_k127_4175217_6	926569.ANT_04130	7.584e-71	262.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GDHHQS2_k127_4175217_4	306281.AJLK01000157_gene5376	7.638e-93	316.0	COG0430@1|root,COG0430@2|Bacteria,1G3A2@1117|Cyanobacteria,1JJEX@1189|Stigonemataceae	1117|Cyanobacteria	A	RNA 3'-terminal phosphate cyclase (RTC), insert domain	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
GDHHQS2_k127_4175217_3	247490.KSU1_B0214	8.199e-96	323.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS2_k127_4175217_1	1210884.HG799462_gene8074	8.535e-126	412.0	COG1090@1|root,COG1090@2|Bacteria,2IYWK@203682|Planctomycetes	203682|Planctomycetes	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS2_k127_4175217_0	926569.ANT_09200	1.245e-131	437.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_4175217_7	357808.RoseRS_3588	4.517e-65	235.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,37807@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA polymerase III, delta prime subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS2_k127_4175217_15	1173264.KI913949_gene3050	6.308e-06	52.0	2CAI9@1|root,32RRG@2|Bacteria,1G7V1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4175217_13	590998.Celf_1176	1.296e-27	119.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4F1PC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GDHHQS2_k127_4175217_2	926550.CLDAP_17570	4.95e-123	403.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_4175217_12	497964.CfE428DRAFT_2242	1.794e-28	118.0	COG0399@1|root,COG0399@2|Bacteria,46T3Z@74201|Verrucomicrobia	74201|Verrucomicrobia	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_4175217_11	1254432.SCE1572_05510	1.949e-33	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4316914_12	1120949.KB903297_gene5503	2.666e-32	145.0	COG0642@1|root,COG2205@2|Bacteria,2IE21@201174|Actinobacteria,4DA1C@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GDHHQS2_k127_4316914_5	179408.Osc7112_1976	4.498e-70	263.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2461@1|root,COG3829@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_4316914_1	247639.MGP2080_02481	2.995e-130	426.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS2_k127_4316914_17	326427.Cagg_1021	2.684e-06	51.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS2_k127_4316914_16	357808.RoseRS_2661	1.772e-06	52.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS2_k127_4316914_15	867845.KI911784_gene2510	2.837e-08	57.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS2_k127_4316914_2	1121380.JNIW01000020_gene3588	1.06e-109	366.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	solA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016647,GO:0033554,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050131,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0097159,GO:1901265,GO:1901363	-	ko:K02846	-	-	-	-	ko00000,ko01000	-	-	iEC042_1314.EC042_1126	DAO
GDHHQS2_k127_4316914_0	926550.CLDAP_01180	6.123e-184	589.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_4316914_18	517418.Ctha_0971	0.0006279	48.0	2CAA6@1|root,2ZH6E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4316914_13	1532557.JL37_10085	1.38e-29	132.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VK1U@28216|Betaproteobacteria,3T2N4@506|Alcaligenaceae	28216|Betaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_4316914_7	416591.Tlet_2006	9.379e-43	169.0	COG1173@1|root,COG1173@2|Bacteria,2GCK9@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_4316914_11	1245471.PCA10_50230	1.158e-32	132.0	COG0251@1|root,COG0251@2|Bacteria,1RH5K@1224|Proteobacteria,1SE2G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_4316914_9	926569.ANT_23510	3.575e-35	149.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GDHHQS2_k127_4316914_8	926569.ANT_23510	8.84e-41	167.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GDHHQS2_k127_4316914_6	765420.OSCT_2218	9.907e-49	193.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2G7J9@200795|Chloroflexi,37522@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
GDHHQS2_k127_4316914_3	646529.Desaci_0102	1.571e-109	369.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
GDHHQS2_k127_4316914_4	926569.ANT_25980	2.382e-104	354.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GDHHQS2_k127_4316914_14	1173022.Cri9333_1828	2.123e-18	91.0	COG1017@1|root,COG1357@1|root,COG1017@2|Bacteria,COG1357@2|Bacteria,1G3MG@1117|Cyanobacteria,1H9R2@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	Globin,Pentapeptide
GDHHQS2_k127_4409304_10	1382356.JQMP01000003_gene1423	4.394e-30	134.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_4409304_9	1394178.AWOO02000044_gene4471	1.533e-31	134.0	COG3662@1|root,COG3662@2|Bacteria,2GY2Z@201174|Actinobacteria,4EQTZ@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
GDHHQS2_k127_4409304_2	469371.Tbis_2599	6.48e-232	726.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS2_k127_4409304_5	765420.OSCT_0642	4.111e-112	368.0	COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi,376QK@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4409304_4	765420.OSCT_0643	2.644e-127	432.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4409304_3	479434.Sthe_1319	6.532e-207	657.0	COG1866@1|root,COG1866@2|Bacteria,2G5TD@200795|Chloroflexi,27YZT@189775|Thermomicrobia	189775|Thermomicrobia	H	Phosphoenolpyruvate carboxykinase	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
GDHHQS2_k127_4409304_7	1206720.BAFQ01000052_gene1262	5.337e-80	282.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FYM9@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C,ECH_1
GDHHQS2_k127_4409304_11	1123314.AUIO01000015_gene715	3.555e-08	61.0	COG1846@1|root,COG1846@2|Bacteria,1VB3Q@1239|Firmicutes,4HP7J@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, marr family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS2_k127_4409304_1	316274.Haur_0948	2.25e-264	831.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi,376W8@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_4409304_0	1128421.JAGA01000002_gene1146	1.372e-275	865.0	COG1132@1|root,COG1132@2|Bacteria,2NNP8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	yknV	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K02021,ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_4409304_8	479434.Sthe_1778	5.08e-48	181.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	189775|Thermomicrobia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_4409304_6	1382356.JQMP01000004_gene534	1.951e-95	328.0	COG0793@1|root,COG0793@2|Bacteria,2G6A8@200795|Chloroflexi,27Y0X@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
GDHHQS2_k127_441902_11	1183438.GKIL_2649	2.281e-121	402.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
GDHHQS2_k127_441902_4	1267533.KB906738_gene2028	3.353e-147	471.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
GDHHQS2_k127_441902_0	518766.Rmar_1363	7.475e-321	998.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_441902_18	926569.ANT_06180	1.952e-78	279.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_441902_63	926550.CLDAP_28940	4.814e-13	83.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	YSIRK_signal
GDHHQS2_k127_441902_24	1499967.BAYZ01000090_gene4936	1.66e-62	230.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_441902_51	1444306.JFZC01000046_gene304	6.986e-23	108.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26NJA@186821|Sporolactobacillaceae	91061|Bacilli	E	PFAM extracellular solute-binding protein family 5	dppA	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
GDHHQS2_k127_441902_59	1200792.AKYF01000017_gene5622	1.203e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,1V183@1239|Firmicutes,4IQ36@91061|Bacilli	91061|Bacilli	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_441902_44	1499967.BAYZ01000090_gene4936	1.291e-31	144.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_441902_5	926550.CLDAP_12360	2.719e-146	481.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	Cellulase,Glyco_hydro_1
GDHHQS2_k127_441902_40	1476583.DEIPH_ctg139orf0164	2.414e-41	165.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_441902_58	1521187.JPIM01000031_gene1988	2.259e-18	86.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi,37629@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
GDHHQS2_k127_441902_41	1464048.JNZS01000004_gene1558	4.25e-35	150.0	COG1629@1|root,COG4932@1|root,COG1629@2|Bacteria,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria,4DERA@85008|Micromonosporales	201174|Actinobacteria	M	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
GDHHQS2_k127_441902_66	926550.CLDAP_03020	1.03e-09	68.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS2_k127_441902_22	383372.Rcas_3381	1.595e-68	252.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_441902_37	479434.Sthe_2302	1.739e-44	181.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_441902_23	28444.JODQ01000013_gene2933	7.095e-66	231.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS2_k127_441902_49	562970.Btus_1957	2.377e-24	104.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_441902_13	1128421.JAGA01000003_gene3111	3.745e-112	372.0	COG0809@1|root,COG0809@2|Bacteria,2NNWD@2323|unclassified Bacteria	2|Bacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29,2.4.99.17	ko:K00773,ko:K07568	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS2_k127_441902_36	1232437.KL662006_gene4383	1.528e-44	169.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria,2MM35@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_441902_62	768710.DesyoDRAFT_1514	1e-13	74.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS2_k127_441902_43	313606.M23134_05973	1.059e-33	136.0	2DGKH@1|root,2ZWDA@2|Bacteria,4NPWZ@976|Bacteroidetes,47SM0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_441902_61	1385513.N780_15640	4.307e-14	80.0	arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HGUW@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
GDHHQS2_k127_441902_32	765420.OSCT_2707	6.707e-51	192.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_441902_7	945713.IALB_2901	1.098e-136	444.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
GDHHQS2_k127_441902_67	483219.LILAB_20755	2.573e-09	64.0	COG0454@1|root,COG0456@2|Bacteria,1R7PK@1224|Proteobacteria	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS2_k127_441902_31	671143.DAMO_0059	1.169e-51	193.0	COG0272@1|root,COG0758@1|root,COG0272@2|Bacteria,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	2.7.7.7,6.5.1.2	ko:K01972,ko:K02342,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378,R00382	RC00005,RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,DNA_processg_A,HHH_2,HHH_5
GDHHQS2_k127_441902_28	1122221.JHVI01000021_gene2417	1.077e-55	207.0	COG0687@1|root,COG0687@2|Bacteria,1WIQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS2_k127_441902_12	926550.CLDAP_37530	9.572e-119	392.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_441902_29	935261.JAGL01000005_gene3409	4.409e-54	204.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,43H7C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_441902_25	1380391.JIAS01000012_gene4109	1.731e-61	222.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,2JQTE@204441|Rhodospirillales	204441|Rhodospirillales	E	Putrescine transport system permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS2_k127_441902_33	311403.Arad_8244	7.236e-48	187.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TS7M@28211|Alphaproteobacteria,4BENC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
GDHHQS2_k127_441902_42	926550.CLDAP_37590	3.789e-34	137.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	asnC	-	-	ko:K03718,ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS2_k127_441902_30	113395.AXAI01000007_gene1222	1.472e-53	190.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,2U7IF@28211|Alphaproteobacteria,3JYR5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	MA20_27600	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_441902_26	926569.ANT_25680	2.006e-59	218.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS2_k127_441902_15	926569.ANT_19840	3.41e-92	310.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
GDHHQS2_k127_441902_17	926550.CLDAP_18940	8.064e-85	293.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS2_k127_441902_52	1128421.JAGA01000002_gene405	1.338e-22	107.0	2EV3Q@1|root,33NIR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_441902_16	1122919.KB905552_gene498	4.187e-88	299.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,26TDJ@186822|Paenibacillaceae	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS2_k127_441902_2	552811.Dehly_0399	2.894e-238	753.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_441902_19	1382356.JQMP01000003_gene2530	1.187e-76	268.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27Y4V@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_441902_50	4006.Lus10017182	1.553e-23	104.0	COG4323@1|root,2S1IP@2759|Eukaryota,37VGV@33090|Viridiplantae,3GJ74@35493|Streptophyta,4JUCY@91835|fabids	35493|Streptophyta	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GDHHQS2_k127_441902_3	316274.Haur_4945	1.72e-151	496.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS2_k127_441902_54	1123320.KB889565_gene6287	1.128e-21	101.0	COG1846@1|root,COG1846@2|Bacteria,2IM92@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS2_k127_441902_35	526227.Mesil_1024	1.76e-47	174.0	COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_441902_70	1122138.AQUZ01000040_gene6209	3.005e-06	54.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_441902_8	105422.BBPM01000003_gene5688	6.365e-135	444.0	COG0520@1|root,COG0520@2|Bacteria,2IAKT@201174|Actinobacteria,2NGTH@228398|Streptacidiphilus	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS2_k127_441902_6	926569.ANT_24850	5.206e-137	448.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS2_k127_441902_60	391612.CY0110_09847	1.058e-15	85.0	COG1598@1|root,COG1598@2|Bacteria,1G8RN@1117|Cyanobacteria,3KIM2@43988|Cyanothece	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_441902_53	395961.Cyan7425_3185	3.046e-22	97.0	COG1724@1|root,COG1724@2|Bacteria,1G7S1@1117|Cyanobacteria,3KIRS@43988|Cyanothece	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_441902_1	926569.ANT_26670	2.813e-250	782.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS2_k127_441902_46	926550.CLDAP_06590	5.78e-31	125.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS2_k127_441902_45	485913.Krac_4912	2.145e-31	134.0	COG1670@1|root,COG1670@2|Bacteria,2G9F1@200795|Chloroflexi	200795|Chloroflexi	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
GDHHQS2_k127_441902_64	266117.Rxyl_2945	9.404e-13	76.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_441902_34	926569.ANT_03770	1.455e-47	182.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GDHHQS2_k127_441902_38	926569.ANT_03760	4.078e-44	163.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GDHHQS2_k127_441902_10	926560.KE387023_gene1680	5.534e-124	404.0	COG3173@1|root,COG3173@2|Bacteria,1WM3S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS2_k127_441902_21	926569.ANT_03780	5.311e-70	248.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	2|Bacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_441902_9	485913.Krac_2547	6.785e-128	419.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
GDHHQS2_k127_441902_69	1038858.AXBA01000011_gene1469	2.025e-08	62.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,3F1IG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GDHHQS2_k127_441902_39	324925.Ppha_1753	2.163e-42	168.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
GDHHQS2_k127_441902_56	649747.HMPREF0083_00518	1.805e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,4HGUE@91061|Bacilli,2752I@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_441902_48	1382306.JNIM01000001_gene2947	1.148e-24	108.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_441902_57	1540257.JQMW01000013_gene1268	3.992e-20	98.0	2FFQG@1|root,347MS@2|Bacteria,1VZWU@1239|Firmicutes,25CJH@186801|Clostridia,36MZ8@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_441902_14	309801.trd_1268	2.61e-102	340.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,27XRQ@189775|Thermomicrobia	189775|Thermomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_441902_27	1133849.O3I_007565	3.272e-57	203.0	COG1413@1|root,COG1413@2|Bacteria,2IC1N@201174|Actinobacteria,4FYUP@85025|Nocardiaceae	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_441902_20	357808.RoseRS_2229	4.034e-72	271.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_441902_68	296587.XP_002508688.1	8.401e-09	60.0	COG4886@1|root,KOG0619@2759|Eukaryota,388K9@33090|Viridiplantae,34JK4@3041|Chlorophyta	3041|Chlorophyta	S	Leucine-rich repeats, typical (most populated) subfamily	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
GDHHQS2_k127_4431326_14	1382356.JQMP01000003_gene1637	6.84e-06	57.0	COG0726@1|root,COG0726@2|Bacteria,2GA3J@200795|Chloroflexi,27Z0S@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS2_k127_4431326_10	926569.ANT_03580	4.204e-35	155.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431326_11	926550.CLDAP_38690	2.256e-25	115.0	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi	200795|Chloroflexi	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
GDHHQS2_k127_4431326_7	525904.Tter_1028	1.748e-64	234.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314,ko:K02316,ko:K17680	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_N,zf-CHC2
GDHHQS2_k127_4431326_12	716928.AJQT01000035_gene796	8.044e-16	83.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,4BCQ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS2_k127_4431326_9	1382356.JQMP01000001_gene1211	1.22e-37	148.0	COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi,27YBX@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcription regulator	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS2_k127_4431326_4	479434.Sthe_1277	7.497e-83	284.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi,27XNS@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_4431326_6	402777.KB235904_gene4402	1.41e-77	273.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H7XM@1150|Oscillatoriales	1117|Cyanobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_4431326_3	1173029.JH980292_gene3144	6.902e-100	337.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria,1H7WH@1150|Oscillatoriales	1117|Cyanobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS2_k127_4431326_1	476272.RUMHYD_02346	1.515e-139	455.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_4431326_2	309801.trd_0523	1.869e-138	449.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_4431326_13	926692.AZYG01000091_gene1744	4.965e-07	54.0	COG1977@1|root,COG1977@2|Bacteria,1VIUV@1239|Firmicutes,24RKW@186801|Clostridia	186801|Clostridia	H	PFAM ThiamineS	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_4431326_0	1121324.CLIT_8c01210	2.812e-187	604.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS2_k127_4431326_8	1168034.FH5T_17845	1.277e-58	224.0	COG4251@1|root,COG4251@2|Bacteria,4PMMC@976|Bacteroidetes	976|Bacteroidetes	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS_9
GDHHQS2_k127_4431326_5	324602.Caur_1591	5.298e-78	276.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS2_k127_4431326_15	1144313.PMI10_04021	7.484e-05	49.0	2EF6T@1|root,3123K@2|Bacteria,4PGYD@976|Bacteroidetes,1ID7U@117743|Flavobacteriia,2NXMZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_6	706587.Desti_1501	3.98e-107	367.0	COG1807@1|root,COG1807@2|Bacteria,1Q6N9@1224|Proteobacteria,433F2@68525|delta/epsilon subdivisions,2WXMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_4431662_24	1530186.JQEY01000018_gene296	4.764e-05	52.0	COG0589@1|root,COG0589@2|Bacteria,1RDMJ@1224|Proteobacteria,2U769@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_4431662_5	944479.JQLX01000012_gene1042	4.444e-109	374.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2M6A1@213113|Desulfurellales	28221|Deltaproteobacteria	P	Bacterial Na+/H+ antiporter B (NhaB)	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
GDHHQS2_k127_4431662_17	1236504.HMPREF2132_10890	1.279e-23	107.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,2FRB2@200643|Bacteroidia	976|Bacteroidetes	L	Hydrolase, NUDIX family	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_4431662_4	266117.Rxyl_2848	2.402e-125	408.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4CQAT@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS2_k127_4431662_1	926550.CLDAP_38260	1.787e-226	723.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
GDHHQS2_k127_4431662_3	1499967.BAYZ01000060_gene6002	4.838e-166	548.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
GDHHQS2_k127_4431662_7	1382306.JNIM01000001_gene1486	1.937e-86	293.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_4431662_2	1254432.SCE1572_02095	8.135e-223	707.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
GDHHQS2_k127_4431662_23	1128421.JAGA01000002_gene111	1.384e-05	56.0	COG5401@1|root,COG5401@2|Bacteria	2|Bacteria	T	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
GDHHQS2_k127_4431662_22	926550.CLDAP_10820	1.243e-12	78.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
GDHHQS2_k127_4431662_0	926569.ANT_08730	0.0	1050.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
GDHHQS2_k127_4431662_26	1397693.KK211187_gene2462	0.0006591	45.0	2DC3Y@1|root,2ZCTC@2|Bacteria,1U1X5@1239|Firmicutes,4IBDN@91061|Bacilli,3WFTZ@539002|Bacillales incertae sedis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_10	646529.Desaci_4145	1.093e-46	189.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_4431662_12	926569.ANT_20730	1.16e-36	156.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS2_k127_4431662_14	234267.Acid_1609	1e-28	117.0	2E3RU@1|root,32YPG@2|Bacteria,3Y8WT@57723|Acidobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_19	485913.Krac_10734	5.705e-21	95.0	28YKJ@1|root,2ZKEA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_18	1267535.KB906767_gene2040	3.512e-22	100.0	2CGNP@1|root,32S4A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_9	244582.JQAK01000001_gene1815	8.277e-52	187.0	COG3293@1|root,COG3293@2|Bacteria,1MZS4@1224|Proteobacteria,2TXCF@28211|Alphaproteobacteria,47EZ1@766|Rickettsiales	766|Rickettsiales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS2_k127_4431662_16	1144312.PMI09_05600	2.577e-26	111.0	COG3293@1|root,COG3293@2|Bacteria,1N1CW@1224|Proteobacteria,2U8KW@28211|Alphaproteobacteria,4BFMC@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
GDHHQS2_k127_4431662_8	1125863.JAFN01000001_gene151	2.722e-78	278.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,42NPH@68525|delta/epsilon subdivisions,2WIXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Basic membrane	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
GDHHQS2_k127_4431662_11	926560.KE387023_gene2986	2.542e-42	169.0	COG3613@1|root,COG3613@2|Bacteria,1WK4Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
GDHHQS2_k127_4431662_21	195522.BD01_2173	1.169e-14	82.0	COG2019@1|root,arCOG01039@2157|Archaea,2XVK7@28890|Euryarchaeota,242IR@183968|Thermococci	183968|Thermococci	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
GDHHQS2_k127_4431662_20	1462526.BN990_00085	4.193e-16	86.0	COG1428@1|root,COG1428@2|Bacteria,1TQKS@1239|Firmicutes,4HBWC@91061|Bacilli,4C65D@84406|Virgibacillus	91061|Bacilli	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
GDHHQS2_k127_4431662_15	1189612.A33Q_4021	6.572e-27	117.0	COG3663@1|root,COG3663@2|Bacteria,4NEZ4@976|Bacteroidetes	976|Bacteroidetes	L	G T U mismatch-specific DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4431662_13	639283.Snov_0687	2.329e-35	142.0	COG0717@1|root,COG0717@2|Bacteria,1PUSA@1224|Proteobacteria,2V6AV@28211|Alphaproteobacteria,3F0CT@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS2_k127_4612548_19	163908.KB235896_gene2610	8.469e-49	196.0	COG0642@1|root,COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HJ8D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
GDHHQS2_k127_4612548_21	509190.Cseg_3862	7.227e-45	172.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2KFH3@204458|Caulobacterales	204458|Caulobacterales	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4612548_28	56110.Oscil6304_1216	1.146e-18	91.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_4612548_30	981384.AEYW01000006_gene2863	3.848e-12	73.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS2_k127_4612548_17	179408.Osc7112_3669	3.072e-56	209.0	COG0715@1|root,COG0715@2|Bacteria,1G4RQ@1117|Cyanobacteria,1HEFA@1150|Oscillatoriales	1117|Cyanobacteria	P	COGs COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_4612548_18	247490.KSU1_C0338	7.834e-55	214.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2J515@203682|Planctomycetes	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
GDHHQS2_k127_4612548_26	1041147.AUFB01000019_gene5558	5.077e-25	110.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U76I@28211|Alphaproteobacteria,4BMXW@82115|Rhizobiaceae	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4612548_29	748247.AZKH_2727	1.388e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VU99@28216|Betaproteobacteria,2KZ14@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4612548_16	316274.Haur_2966	3.738e-57	223.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_4612548_24	485913.Krac_6369	8.624e-31	128.0	COG0789@1|root,COG0789@2|Bacteria,2G7DC@200795|Chloroflexi	200795|Chloroflexi	K	Transcription regulator MerR DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind
GDHHQS2_k127_4612548_31	749927.AMED_3521	2.472e-07	59.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4E57U@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_4612548_14	1380391.JIAS01000012_gene4124	1.951e-58	216.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,2JXWG@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
GDHHQS2_k127_4612548_3	118161.KB235922_gene3489	2.494e-161	517.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Hydrolase_4,Peptidase_S9
GDHHQS2_k127_4612548_10	1437425.CSEC_0731	1.293e-80	278.0	COG1028@1|root,COG1028@2|Bacteria	1437425.CSEC_0731|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4612548_23	867845.KI911784_gene226	1.24e-40	158.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_4612548_11	526227.Mesil_3179	7.985e-76	266.0	COG1609@1|root,COG1609@2|Bacteria,1WMBZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_4612548_2	926550.CLDAP_09870	2.424e-189	608.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
GDHHQS2_k127_4612548_0	926550.CLDAP_06990	1.602e-253	795.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GDHHQS2_k127_4612548_4	926550.CLDAP_06960	3.794e-153	495.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_4612548_1	926550.CLDAP_06970	6.064e-208	664.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
GDHHQS2_k127_4612548_15	926550.CLDAP_06980	1.684e-57	205.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
GDHHQS2_k127_4612548_6	1123371.ATXH01000016_gene1837	4.473e-117	398.0	COG1055@1|root,COG1055@2|Bacteria,2GGU6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
GDHHQS2_k127_4612548_32	1266998.ATUJ01000006_gene91	8.968e-05	50.0	COG0589@1|root,COG0589@2|Bacteria,1RDMJ@1224|Proteobacteria,2U769@28211|Alphaproteobacteria,2PYPI@265|Paracoccus	28211|Alphaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_4612548_7	68170.KL590486_gene9692	9.18e-102	339.0	COG1131@1|root,COG1131@2|Bacteria,2IBP5@201174|Actinobacteria,4E9YU@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4612548_13	68170.KL590486_gene9693	1.605e-61	220.0	COG1277@1|root,COG1277@2|Bacteria,2IING@201174|Actinobacteria,4E5D6@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
GDHHQS2_k127_4612548_22	316274.Haur_2135	1.058e-44	171.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS2_k127_4612548_5	383372.Rcas_2658	7.475e-127	413.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
GDHHQS2_k127_4612548_20	1226994.AMZB01000117_gene2610	8.054e-48	177.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,1RP4F@1236|Gammaproteobacteria,1YDNQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dipZ	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
GDHHQS2_k127_4612548_9	316274.Haur_4664	5.078e-87	302.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_4612548_12	909613.UO65_4998	2.604e-73	253.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4DYFF@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4612548_27	662479.C440_17076	1.14e-23	110.0	arCOG06181@1|root,arCOG06181@2157|Archaea,2Y06C@28890|Euryarchaeota,23XFD@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4612548_25	662479.C440_17081	3.442e-25	113.0	arCOG02399@1|root,arCOG02399@2157|Archaea,2XVVI@28890|Euryarchaeota,23UYC@183963|Halobacteria	183963|Halobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS2_k127_4612548_8	981384.AEYW01000018_gene3160	5.139e-98	338.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TQXY@28211|Alphaproteobacteria,4NDRU@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
GDHHQS2_k127_4612548_33	379066.GAU_1942	0.0004889	52.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_4624730_34	927677.ALVU02000001_gene1398	2.553e-36	141.0	COG2154@1|root,COG2154@2|Bacteria,1G6T6@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS2_k127_4624730_39	340.xcc-b100_1370	5.772e-25	109.0	2EHW5@1|root,33BMQ@2|Bacteria,1P29Q@1224|Proteobacteria,1T710@1236|Gammaproteobacteria,1X8K7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_1	926569.ANT_05230	2.156e-253	796.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
GDHHQS2_k127_4624730_49	1214101.BN159_0927	0.0006584	46.0	2F6FU@1|root,33YYY@2|Bacteria,2IMKU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_45	326427.Cagg_2496	6.537e-08	64.0	COG0515@1|root,COG3266@1|root,COG0515@2|Bacteria,COG3266@2|Bacteria,2GBJD@200795|Chloroflexi,375Z0@32061|Chloroflexia	32061|Chloroflexia	KLT	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_44	224325.AF_1672	5.748e-09	63.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GDHHQS2_k127_4624730_29	69014.TK0711	2.664e-51	186.0	COG1720@1|root,arCOG00761@2157|Archaea,2XY3D@28890|Euryarchaeota,2440R@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GDHHQS2_k127_4624730_26	926560.KE387023_gene2085	2.008e-55	210.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,SIR2_2,Trypsin_2
GDHHQS2_k127_4624730_9	1121091.AUMP01000001_gene539	2.169e-137	449.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli	91061|Bacilli	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_4624730_21	926569.ANT_14300	6.294e-76	261.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4624730_27	1121926.AXWO01000013_gene2090	1.987e-54	205.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EZNF@85014|Glycomycetales	201174|Actinobacteria	T	GAF domain	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS2_k127_4624730_24	926550.CLDAP_11930	2.145e-65	255.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
GDHHQS2_k127_4624730_6	234267.Acid_4597	5.713e-179	570.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS2_k127_4624730_11	383372.Rcas_3656	3.443e-118	388.0	COG0451@1|root,COG0451@2|Bacteria,2G7TT@200795|Chloroflexi	200795|Chloroflexi	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_4624730_13	1382359.JIAL01000001_gene2599	3.96e-117	385.0	COG1087@1|root,COG1087@2|Bacteria,3Y3FK@57723|Acidobacteria,2JI2G@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_4624730_18	926550.CLDAP_12370	1.985e-81	295.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_28	644966.Tmar_0071	2.142e-52	188.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WCJG@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
GDHHQS2_k127_4624730_46	1207063.P24_17558	4.626e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
GDHHQS2_k127_4624730_40	402881.Plav_2815	3.987e-22	100.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,1JNCR@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	diguanylate cyclase	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_4624730_12	316274.Haur_1254	1.843e-117	383.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
GDHHQS2_k127_4624730_36	163908.KB235896_gene3386	7.941e-35	139.0	COG1848@1|root,COG1848@2|Bacteria,1GKWX@1117|Cyanobacteria,1HQYF@1161|Nostocales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_43	1469607.KK073768_gene4777	3.885e-10	64.0	2EGP4@1|root,33AF9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_48	1121428.DESHY_40085___1	0.0003508	50.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
GDHHQS2_k127_4624730_31	765420.OSCT_1559	1.448e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4624730_33	306281.AJLK01000240_gene2864	4.754e-38	147.0	COG3415@1|root,COG3415@2|Bacteria,1GKNF@1117|Cyanobacteria,1JMRR@1189|Stigonemataceae	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
GDHHQS2_k127_4624730_16	288000.BBta_1402	2.469e-89	299.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria,3JWD8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GDHHQS2_k127_4624730_47	266117.Rxyl_0586	0.000185	46.0	COG1476@1|root,COG1598@1|root,COG1476@2|Bacteria,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	ko:K03088,ko:K07110	-	-	-	-	ko00000,ko03000,ko03021	-	-	-	HTH_3,HTH_31,Peptidase_M78
GDHHQS2_k127_4624730_23	926550.CLDAP_16230	1.463e-67	241.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
GDHHQS2_k127_4624730_3	926550.CLDAP_10520	3.748e-204	659.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS2_k127_4624730_5	926550.CLDAP_26830	3.965e-181	590.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4624730_38	1278073.MYSTI_02265	2.755e-26	121.0	COG2887@1|root,COG2887@2|Bacteria,1QXTW@1224|Proteobacteria,43C6C@68525|delta/epsilon subdivisions,2X7GI@28221|Deltaproteobacteria,2YZ5R@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
GDHHQS2_k127_4624730_41	1111728.ATYS01000025_gene4243	5.471e-20	102.0	2DC1F@1|root,2ZCE5@2|Bacteria,1RCQ9@1224|Proteobacteria,1S28C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
GDHHQS2_k127_4624730_8	557598.LHK_01304	2.969e-145	477.0	COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,2VNQK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-ligase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
GDHHQS2_k127_4624730_4	1115512.EH105704_04_00550	2.155e-181	578.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,1RQEG@1236|Gammaproteobacteria,3XRND@561|Escherichia	1236|Gammaproteobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
GDHHQS2_k127_4624730_20	1499967.BAYZ01000105_gene3490	7.062e-77	262.0	COG4845@1|root,COG4845@2|Bacteria	2|Bacteria	V	Chloramphenicol acetyltransferase	cat3	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT,TPR_5
GDHHQS2_k127_4624730_19	1298867.AUES01000006_gene345	2.047e-80	277.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS2_k127_4624730_22	1382356.JQMP01000003_gene1477	2.062e-74	255.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS2_k127_4624730_7	309801.trd_0580	1.805e-145	464.0	COG1878@1|root,COG1878@2|Bacteria,2GBDZ@200795|Chloroflexi,27Z1S@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS2_k127_4624730_35	756067.MicvaDRAFT_3864	2.063e-35	138.0	COG2337@1|root,COG2337@2|Bacteria,1G7SY@1117|Cyanobacteria,1HCGM@1150|Oscillatoriales	1117|Cyanobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS2_k127_4624730_0	1038860.AXAP01000027_gene1889	0.0	1109.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS2_k127_4624730_14	106648.BBLJ01000001_gene2252	1.706e-92	320.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,3NQQ9@468|Moraxellaceae	1236|Gammaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_4624730_17	555088.DealDRAFT_0418	1.038e-85	290.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_4624730_32	1128421.JAGA01000002_gene1440	7.789e-42	163.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.301	ko:K21459	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
GDHHQS2_k127_4624730_25	517418.Ctha_2407	1.348e-56	204.0	COG0400@1|root,COG0400@2|Bacteria,1FE1K@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS2_k127_4624730_10	1120973.AQXL01000133_gene1763	8.214e-120	391.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4HCR0@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS2_k127_4624730_15	1317122.ATO12_22555	7.542e-90	302.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1HYU7@117743|Flavobacteriia,2YING@290174|Aquimarina	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS2_k127_4624730_2	562970.Btus_1576	1.297e-205	652.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,279JK@186823|Alicyclobacillaceae	91061|Bacilli	C	Aldehyde dehydrogenase family	-	-	1.2.1.60	ko:K00151	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04418	RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_4624730_42	864702.OsccyDRAFT_4037	8.764e-12	70.0	COG2127@1|root,COG2127@2|Bacteria,1GCV3@1117|Cyanobacteria,1HF6U@1150|Oscillatoriales	1117|Cyanobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
GDHHQS2_k127_4624730_30	351348.Maqu_0228	7.75e-51	207.0	COG0457@1|root,COG0457@2|Bacteria,1QV4P@1224|Proteobacteria,1SJ0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
GDHHQS2_k127_4624730_50	1206741.BAFX01000102_gene1437	0.0009658	51.0	COG1309@1|root,COG1309@2|Bacteria,2IMF7@201174|Actinobacteria,4FTZX@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS2_k127_463081_12	926569.ANT_13240	4.974e-155	499.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS2_k127_463081_64	1229276.DI53_0293	2.59e-19	92.0	2E2BG@1|root,32XGP@2|Bacteria,4NTW3@976|Bacteroidetes	976|Bacteroidetes	S	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_463081_15	555079.Toce_1855	7.673e-145	466.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS2_k127_463081_18	926569.ANT_13260	2.961e-121	403.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GDHHQS2_k127_463081_54	886293.Sinac_5289	8.037e-30	130.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS2_k127_463081_26	497964.CfE428DRAFT_4876	7.265e-78	266.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS2_k127_463081_60	1254432.SCE1572_30630	1.475e-23	107.0	COG1748@1|root,COG1748@2|Bacteria,1PSWY@1224|Proteobacteria,433TJ@68525|delta/epsilon subdivisions,2X3EI@28221|Deltaproteobacteria,2YVQC@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
GDHHQS2_k127_463081_45	926569.ANT_17930	1.728e-38	147.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS2_k127_463081_49	690850.Desaf_3456	8.802e-36	143.0	2C6MB@1|root,32951@2|Bacteria,1P561@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_13	1459636.NTE_02652	3.129e-154	497.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_463081_55	316274.Haur_2531	1.948e-29	123.0	COG0822@1|root,COG0822@2|Bacteria,2GAEI@200795|Chloroflexi,375SH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM nitrogen-fixing NifU domain protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS2_k127_463081_17	926569.ANT_17960	3.836e-127	420.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_463081_2	926569.ANT_17970	1.572e-238	743.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS2_k127_463081_20	926569.ANT_17980	3.733e-115	376.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS2_k127_463081_38	926569.ANT_17990	2.475e-45	173.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS2_k127_463081_62	926569.ANT_18000	4.727e-22	98.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS2_k127_463081_73	1157637.KB892093_gene6788	8.642e-06	57.0	2CDI5@1|root,2Z7ZQ@2|Bacteria,2I8FG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_23	1230476.C207_02861	4.722e-98	335.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,3JQN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP
GDHHQS2_k127_463081_48	330214.NIDE1190	1.341e-36	152.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_463081_7	926550.CLDAP_24930	1.245e-184	584.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_463081_61	645991.Sgly_0672	1.585e-22	105.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,262DS@186807|Peptococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS2_k127_463081_5	1380390.JIAT01000009_gene493	2.543e-193	616.0	COG1231@1|root,COG1231@2|Bacteria,2I8ZQ@201174|Actinobacteria,4CRBP@84995|Rubrobacteria	84995|Rubrobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS2_k127_463081_27	351160.RCIX982	1.125e-77	268.0	COG0596@1|root,arCOG01648@2157|Archaea,2XVV6@28890|Euryarchaeota	28890|Euryarchaeota	H	Alpha beta fold family hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_463081_0	926550.CLDAP_20840	5.631e-281	874.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GDHHQS2_k127_463081_72	255470.cbdbA614	5.43e-06	61.0	2A4AU@1|root,30SWE@2|Bacteria,2GARB@200795|Chloroflexi,34D5K@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_40	1121930.AQXG01000007_gene490	1.124e-44	188.0	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_19	1007103.AFHW01000013_gene6127	2.273e-116	380.0	COG0084@1|root,COG0084@2|Bacteria,1TQRF@1239|Firmicutes,4HDI4@91061|Bacilli,26S6T@186822|Paenibacillaceae	91061|Bacilli	L	TatD related DNase	mttC	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS2_k127_463081_65	1209989.TepiRe1_1592	4.033e-15	79.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,42FT9@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM sporulation protein, yteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
GDHHQS2_k127_463081_25	1089553.Tph_c12970	1.419e-82	284.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS2_k127_463081_70	1394178.AWOO02000056_gene777	1.242e-08	65.0	COG0500@1|root,COG2226@2|Bacteria,2I1M7@201174|Actinobacteria,4EKZU@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_463081_36	1232683.ADIMK_3763	1.167e-48	196.0	COG1361@1|root,COG1361@2|Bacteria,1R2T2@1224|Proteobacteria,1T5WX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_67	926569.ANT_25610	3.712e-10	69.0	COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi	200795|Chloroflexi	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS2_k127_463081_52	926569.ANT_11850	3.044e-33	132.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_463081_31	926569.ANT_11840	3.836e-56	204.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_463081_53	926550.CLDAP_03540	3.098e-30	139.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
GDHHQS2_k127_463081_37	926569.ANT_11810	5.967e-46	185.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
GDHHQS2_k127_463081_35	926569.ANT_11800	5.189e-49	197.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS2_k127_463081_75	76114.ebA2797	0.0002439	54.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,2VN2D@28216|Betaproteobacteria,2KVSK@206389|Rhodocyclales	206389|Rhodocyclales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
GDHHQS2_k127_463081_39	926569.ANT_11830	9.061e-45	183.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
GDHHQS2_k127_463081_28	926569.ANT_11800	7.56e-68	257.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS2_k127_463081_21	1502851.FG93_00182	1.005e-112	413.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
GDHHQS2_k127_463081_8	926569.ANT_11770	7.128e-161	524.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_463081_34	926569.ANT_11760	1.012e-52	198.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_463081_50	743719.PaelaDRAFT_3980	1.323e-34	139.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,4HGP5@91061|Bacilli,26WI0@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	yyaR	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_463081_51	1173021.ALWA01000019_gene527	1.811e-33	140.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_463081_9	926569.ANT_05360	1.062e-159	522.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GDHHQS2_k127_463081_71	1185876.BN8_01959	2.742e-07	57.0	2EBYQ@1|root,335Y0@2|Bacteria,4NVN8@976|Bacteroidetes,47X01@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_57	382464.ABSI01000010_gene3730	4.964e-27	116.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS2_k127_463081_4	926550.CLDAP_21630	1.198e-196	624.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS2_k127_463081_46	290315.Clim_1053	1.104e-36	147.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
GDHHQS2_k127_463081_1	926550.CLDAP_21610	1.059e-250	782.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS2_k127_463081_16	706587.Desti_4182	2.581e-131	429.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MR27@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS2_k127_463081_42	765420.OSCT_2236	7.635e-43	182.0	COG3292@1|root,COG3829@1|root,COG4585@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2G7P1@200795|Chloroflexi	200795|Chloroflexi	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
GDHHQS2_k127_463081_24	383372.Rcas_2470	6.268e-85	317.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS2_k127_463081_58	1174528.JH992898_gene699	4.997e-26	126.0	COG0784@1|root,COG2202@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5000@2|Bacteria,1GHJE@1117|Cyanobacteria,1JMX7@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_463081_33	485913.Krac_11754	7.661e-53	202.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GDHHQS2_k127_463081_66	886293.Sinac_4414	1.471e-13	83.0	COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SBP_bac_10
GDHHQS2_k127_463081_63	926550.CLDAP_01930	3.516e-21	110.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS2_k127_463081_14	1380394.JADL01000026_gene4735	9.453e-152	495.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2JQDT@204441|Rhodospirillales	204441|Rhodospirillales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS2_k127_463081_3	671143.DAMO_2972	2.701e-233	737.0	COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria	2|Bacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
GDHHQS2_k127_463081_41	215803.DB30_2799	5.382e-43	164.0	COG2258@1|root,COG2258@2|Bacteria,1QVP9@1224|Proteobacteria,438SH@68525|delta/epsilon subdivisions,2X2ED@28221|Deltaproteobacteria,2YXNU@29|Myxococcales	28221|Deltaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
GDHHQS2_k127_463081_30	485913.Krac_6311	2.153e-58	213.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_463081_10	1089548.KI783301_gene238	4.171e-159	515.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3WDZI@539002|Bacillales incertae sedis	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS2_k127_463081_74	1283283.ATXA01000002_gene2474	3.331e-05	46.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4EWG2@85013|Frankiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS2_k127_463081_68	1218108.KB908291_gene438	4.435e-09	63.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
GDHHQS2_k127_463081_6	357808.RoseRS_3533	1.368e-189	614.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,37579@32061|Chloroflexia	32061|Chloroflexia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS2_k127_463081_43	479432.Sros_6135	8.664e-43	162.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	MA20_38135	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2
GDHHQS2_k127_463081_11	1385515.N791_14130	1.631e-155	500.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales	135614|Xanthomonadales	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS2_k127_463081_32	867845.KI911784_gene3104	4.414e-53	191.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_463081_59	1128427.KB904821_gene1548	5.181e-24	106.0	COG2402@1|root,COG2402@2|Bacteria,1G6UZ@1117|Cyanobacteria,1HCNZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_463081_22	1128421.JAGA01000003_gene3228	1.977e-107	358.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_463081_47	1476583.DEIPH_ctg139orf0164	1.285e-36	151.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_463081_56	1449044.JMLE01000040_gene1826	6.997e-28	120.0	2F92T@1|root,341EE@2|Bacteria,2GPMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_463081_29	211165.AJLN01000116_gene3217	5.324e-61	232.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1G35U@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_4645800_17	479434.Sthe_1250	3.13e-07	55.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS2_k127_4645800_2	926569.ANT_11300	6.468e-92	324.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_4645800_7	926550.CLDAP_01930	2.698e-41	173.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS2_k127_4645800_10	926550.CLDAP_01950	1.257e-31	142.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	DUF3367,PMT_2
GDHHQS2_k127_4645800_13	316274.Haur_4794	2.742e-23	102.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi,375SU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GDHHQS2_k127_4645800_0	357808.RoseRS_0089	6.655e-120	394.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS2_k127_4645800_11	357808.RoseRS_2414	1.469e-28	125.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GDHHQS2_k127_4645800_12	1123322.KB904680_gene3285	7.359e-27	122.0	COG1670@1|root,COG1670@2|Bacteria,2I39Q@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
GDHHQS2_k127_4645800_14	1265505.ATUG01000001_gene3978	4.905e-23	107.0	COG2203@1|root,COG2203@2|Bacteria,1NT6X@1224|Proteobacteria,42XRB@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
GDHHQS2_k127_4645800_16	484770.UFO1_4003	1.776e-19	99.0	COG0697@1|root,COG0697@2|Bacteria,1V05H@1239|Firmicutes,4H3UH@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_4645800_15	1297742.A176_07308	3.899e-22	110.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,42WQ8@68525|delta/epsilon subdivisions,2WRZN@28221|Deltaproteobacteria,2Z2IN@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_4645800_8	926550.CLDAP_01930	1.773e-38	164.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS2_k127_4645800_18	1172188.KB911823_gene530	3.422e-07	58.0	2E6D0@1|root,3310N@2|Bacteria,2GQP8@201174|Actinobacteria,4FHHK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
GDHHQS2_k127_4645800_9	1128421.JAGA01000003_gene3335	7.512e-33	131.0	COG2207@1|root,COG2207@2|Bacteria,2NS1E@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	araC	-	-	ko:K21701	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding_2,HTH_18
GDHHQS2_k127_4645800_6	710421.Mycch_2983	9.436e-48	178.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria,239IG@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_4645800_5	1128421.JAGA01000002_gene272	1.837e-48	183.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
GDHHQS2_k127_4645800_4	926569.ANT_00170	2.78e-69	243.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS2_k127_4645800_1	926569.ANT_19080	5.448e-112	379.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS2_k127_4645800_3	316274.Haur_4839	5.928e-75	261.0	COG3485@1|root,COG3485@2|Bacteria,2G7YE@200795|Chloroflexi,375Z5@32061|Chloroflexia	32061|Chloroflexia	C	PFAM intradiol ring-cleavage dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
GDHHQS2_k127_4657345_0	926560.KE387027_gene437	5.53e-107	356.0	COG1541@1|root,COG1541@2|Bacteria,1WM4P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4657345_2	1382306.JNIM01000001_gene2831	2.31e-18	92.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4657345_3	1174528.JH992889_gene74	5.747e-10	64.0	2DVDD@1|root,32UZ7@2|Bacteria,1GAMG@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
GDHHQS2_k127_4657345_4	580327.Tthe_0737	1.943e-09	65.0	2EMRE@1|root,33FDW@2|Bacteria,1VNPH@1239|Firmicutes,24UTS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4657345_1	395494.Galf_2722	6.908e-21	101.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4657345_6	525367.HMPREF0556_11170	7.225e-05	51.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,26JXQ@186820|Listeriaceae	91061|Bacilli	P	Cation transport ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_4661128_25	1462527.CCDM010000002_gene921	4.189e-21	102.0	COG1402@1|root,COG1402@2|Bacteria,1TT2A@1239|Firmicutes,4HPJV@91061|Bacilli	91061|Bacilli	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
GDHHQS2_k127_4661128_24	926569.ANT_20740	1.421e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4661128_31	446470.Snas_5691	8.004e-05	54.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria,4EYPD@85014|Glycomycetales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4661128_18	395495.Lcho_0242	1.28e-35	144.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ32@28216|Betaproteobacteria,1KK16@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	gacA	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS2_k127_4661128_4	926550.CLDAP_27100	1.055e-92	312.0	COG0434@1|root,COG0434@2|Bacteria,2G6UF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
GDHHQS2_k127_4661128_14	1121342.AUCO01000015_gene2690	4.035e-46	188.0	COG3379@1|root,COG3379@2|Bacteria,1VFGU@1239|Firmicutes,25B6K@186801|Clostridia	186801|Clostridia	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_4661128_13	1535287.JP74_01415	1.303e-46	174.0	COG2256@1|root,COG2256@2|Bacteria,1RBJI@1224|Proteobacteria,2U6PX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	atpase related to the helicase subunit of the holliday junction resolvase	-	-	-	-	-	-	-	-	-	-	-	-	MgsA_C
GDHHQS2_k127_4661128_29	1173020.Cha6605_6262	1.322e-06	53.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4661128_19	768671.ThimaDRAFT_3026	3.865e-35	138.0	COG1403@1|root,COG1403@2|Bacteria,1NI19@1224|Proteobacteria,1SIZN@1236|Gammaproteobacteria,1X1ZF@135613|Chromatiales	135613|Chromatiales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4661128_5	1123073.KB899241_gene2032	1.975e-88	301.0	COG1957@1|root,COG1957@2|Bacteria,1RJ6V@1224|Proteobacteria,1SZDM@1236|Gammaproteobacteria,1XCUG@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the IUNH family	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS2_k127_4661128_17	485913.Krac_5098	2.381e-42	158.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_4661128_30	251221.35211765	1.32e-05	56.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_4661128_10	1347369.CCAD010000065_gene3754	9.905e-60	217.0	COG0596@1|root,COG0596@2|Bacteria,1V0M4@1239|Firmicutes,4HPRJ@91061|Bacilli,1ZHQC@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_4661128_3	158190.SpiGrapes_1415	1.878e-131	435.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_4661128_6	383372.Rcas_3765	6.77e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,376FG@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS2_k127_4661128_16	764299.STRIC_1890	8.671e-43	170.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,4HHWZ@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_4661128_22	573370.DMR_p1_00380	2.445e-28	132.0	2904E@1|root,2ZMUC@2|Bacteria,1P5ZS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4661128_28	877455.Metbo_1151	3.799e-10	67.0	COG2329@1|root,arCOG05403@2157|Archaea,2Y22C@28890|Euryarchaeota	28890|Euryarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4661128_0	945713.IALB_2739	2.801e-228	714.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS2_k127_4661128_23	706587.Desti_4566	2.699e-28	130.0	COG2244@1|root,COG2244@2|Bacteria,1MXWW@1224|Proteobacteria,42QPZ@68525|delta/epsilon subdivisions,2WP5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
GDHHQS2_k127_4661128_15	1449049.JONW01000005_gene1920	3.561e-45	177.0	294XI@1|root,2ZSAH@2|Bacteria,1RDZH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
GDHHQS2_k127_4661128_11	1041522.MCOL_V218676	6.828e-59	215.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS2_k127_4661128_9	158189.SpiBuddy_2429	1.379e-67	243.0	COG4603@1|root,COG4603@2|Bacteria,2JAG2@203691|Spirochaetes	203691|Spirochaetes	P	transport system permease	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_4661128_27	237609.PSAKL28_48840	1.024e-18	91.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S4NE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Type IV pilus response regulator PilH	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
GDHHQS2_k127_4661128_26	215803.DB30_0445	1.033e-19	98.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions,2X77E@28221|Deltaproteobacteria,2YUM9@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_4661128_12	765420.OSCT_2550	1.626e-48	182.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4661128_7	383372.Rcas_0805	6.598e-78	299.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
GDHHQS2_k127_4661128_21	1173028.ANKO01000037_gene3748	1.652e-29	139.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8
GDHHQS2_k127_4661128_20	383372.Rcas_2639	1.447e-33	153.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
GDHHQS2_k127_4661128_2	867845.KI911784_gene693	7.204e-175	556.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi,376ZS@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
GDHHQS2_k127_4661128_1	1031288.AXAA01000003_gene1730	9.82e-226	709.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
GDHHQS2_k127_4661128_8	857293.CAAU_0340	1.594e-69	238.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,36E6T@31979|Clostridiaceae	186801|Clostridia	G	ABC-type xylose transport system, periplasmic component	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
GDHHQS2_k127_4678661_17	717606.PaecuDRAFT_1532	3.714e-34	145.0	COG0438@1|root,COG0438@2|Bacteria,1UY5R@1239|Firmicutes	1239|Firmicutes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GDHHQS2_k127_4678661_15	1237149.C900_03017	4.182e-42	165.0	COG0457@1|root,COG0457@2|Bacteria,4PPR7@976|Bacteroidetes	976|Bacteroidetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4678661_13	481448.Minf_2068	2.771e-46	178.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	yxbB	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GDHHQS2_k127_4678661_1	1128421.JAGA01000002_gene1768	1.867e-120	402.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_4678661_26	909613.UO65_3075	0.000502	52.0	2CIK4@1|root,33N0E@2|Bacteria,2IBGS@201174|Actinobacteria,4E1JM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4678661_4	706587.Desti_5503	1.009e-94	338.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GDHHQS2_k127_4678661_6	485913.Krac_5030	6.482e-80	277.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_4678661_14	318464.IO99_06635	1.448e-45	175.0	COG0500@1|root,COG2226@2|Bacteria,1UFKC@1239|Firmicutes,24H53@186801|Clostridia,36I5D@31979|Clostridiaceae	186801|Clostridia	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Ubie_methyltran
GDHHQS2_k127_4678661_7	1242864.D187_000281	4.59e-77	271.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS2_k127_4678661_12	47839.CCAU010000004_gene892	2.548e-48	183.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS2_k127_4678661_11	1379698.RBG1_1C00001G1071	6.544e-51	187.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4678661_20	118173.KB235914_gene2483	7.711e-21	100.0	COG0515@1|root,COG0515@2|Bacteria,1GA6I@1117|Cyanobacteria,1HH09@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS2_k127_4678661_19	383372.Rcas_0553	2.48e-23	107.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_4678661_23	373994.Riv7116_2000	3.459e-14	74.0	2BKR4@1|root,32F71@2|Bacteria,1GJZQ@1117|Cyanobacteria,1HSZ2@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4678661_0	326427.Cagg_2096	2.527e-141	455.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_4678661_9	1298863.AUEP01000022_gene1863	7.603e-54	199.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
GDHHQS2_k127_4678661_2	1120973.AQXL01000131_gene2037	4.76e-103	345.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,278XF@186823|Alicyclobacillaceae	91061|Bacilli	C	Dehydrogenase E1 component	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
GDHHQS2_k127_4678661_10	1173023.KE650771_gene3983	1.945e-53	190.0	COG3393@1|root,COG3393@2|Bacteria,1GF6E@1117|Cyanobacteria	1117|Cyanobacteria	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
GDHHQS2_k127_4678661_5	649747.HMPREF0083_01770	2.702e-86	293.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,2729A@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
GDHHQS2_k127_4678661_8	926550.CLDAP_08330	1.487e-61	221.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS2_k127_4678661_3	485913.Krac_2049	3.212e-98	344.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_4678661_16	1267535.KB906767_gene735	1.393e-40	161.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4678661_22	479434.Sthe_0717	8.197e-15	82.0	2BCVK@1|root,326GC@2|Bacteria,2G9HU@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3995)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3995
GDHHQS2_k127_4678661_24	754027.HMPREF9554_02694	6.317e-11	70.0	COG2020@1|root,COG2020@2|Bacteria,2J7FU@203691|Spirochaetes	203691|Spirochaetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT,YgbA_NO
GDHHQS2_k127_4678661_21	926569.ANT_06730	1.258e-16	84.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_30	926550.CLDAP_32860	5.001e-37	148.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS2_k127_4682920_29	357808.RoseRS_1234	1.248e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4682920_32	357808.RoseRS_1235	1.738e-33	141.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_36	926550.CLDAP_25240	1.657e-25	115.0	COG1547@1|root,COG3437@1|root,COG1547@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309,HD
GDHHQS2_k127_4682920_47	426355.Mrad2831_2672	7.489e-14	79.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TXMN@28211|Alphaproteobacteria,1JQWM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_4682920_0	926550.CLDAP_18930	5.533e-195	617.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_4682920_56	13689.BV96_02776	0.0006646	51.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3,PD40
GDHHQS2_k127_4682920_48	479434.Sthe_3270	1.047e-11	76.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_23	1380390.JIAT01000009_gene444	1.043e-53	196.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CQXP@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_4682920_42	404589.Anae109_3621	6.642e-20	93.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria	1224|Proteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS2_k127_4682920_53	1341151.ASZU01000015_gene2089	0.0001137	51.0	2AYX9@1|root,31R2Z@2|Bacteria,1V1KP@1239|Firmicutes,4HFV5@91061|Bacilli	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4682920_49	1345695.CLSA_c34220	7.621e-10	70.0	2DC40@1|root,2ZCTG@2|Bacteria,1W2CM@1239|Firmicutes,24Q94@186801|Clostridia,36M29@31979|Clostridiaceae	186801|Clostridia	S	cell wall binding	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
GDHHQS2_k127_4682920_50	1321778.HMPREF1982_01578	3.284e-06	58.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_35	913865.DOT_6127	4.31e-26	116.0	2CIHT@1|root,2ZHS8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GDHHQS2_k127_4682920_26	326427.Cagg_3653	1.369e-50	188.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi,375NH@32061|Chloroflexia	32061|Chloroflexia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
GDHHQS2_k127_4682920_12	357808.RoseRS_2229	1.614e-76	293.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_4682920_10	1120971.AUCA01000049_gene794	1.963e-83	291.0	COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_4682920_44	1173024.KI912152_gene624	8.024e-17	93.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,DUF262
GDHHQS2_k127_4682920_22	742735.HMPREF9467_05103	5.714e-55	211.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_2,TPR_8
GDHHQS2_k127_4682920_9	357808.RoseRS_2229	2.128e-90	323.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_4682920_6	1123508.JH636443_gene4982	2.526e-102	339.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_8	504472.Slin_1061	9.283e-95	318.0	COG2267@1|root,COG2267@2|Bacteria,4PKB6@976|Bacteroidetes,47JMT@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_4682920_39	1321784.HMPREF1987_01095	3.689e-21	100.0	COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia,25UK4@186804|Peptostreptococcaceae	186801|Clostridia	L	PFAM nuclease (SNase	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,Cu_amine_oxidN1,SNase
GDHHQS2_k127_4682920_46	32057.KB217478_gene7457	1.141e-14	83.0	COG1403@1|root,COG1403@2|Bacteria,1G180@1117|Cyanobacteria,1HK43@1161|Nostocales	1117|Cyanobacteria	L	PFAM HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS2_k127_4682920_52	189425.PGRAT_17720	7.921e-05	54.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1V1C5@1239|Firmicutes,4HG15@91061|Bacilli,26Q99@186822|Paenibacillaceae	91061|Bacilli	K	arsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20,HTH_5
GDHHQS2_k127_4682920_7	357808.RoseRS_1236	7.647e-97	326.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,376BU@32061|Chloroflexia	2|Bacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4682920_21	383372.Rcas_3764	4.561e-55	203.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GDHHQS2_k127_4682920_25	926550.CLDAP_16430	1.724e-51	192.0	COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS2_k127_4682920_33	1094980.Mpsy_2848	2.842e-30	126.0	COG5513@1|root,arCOG03547@2157|Archaea,2Y4G7@28890|Euryarchaeota,2NB6K@224756|Methanomicrobia	224756|Methanomicrobia	G	serine-type aminopeptidase activity	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	-
GDHHQS2_k127_4682920_37	1033743.CAES01000020_gene3197	4.854e-22	105.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,26RYZ@186822|Paenibacillaceae	91061|Bacilli	KT	LuxR family transcriptional regulator	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS2_k127_4682920_43	426117.M446_3558	1.182e-19	93.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2TXMN@28211|Alphaproteobacteria,1JQWM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_4682920_19	1382306.JNIM01000001_gene1162	1.4e-57	226.0	COG0642@1|root,COG2205@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA,dCache_1
GDHHQS2_k127_4682920_40	926569.ANT_30040	2.181e-20	95.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4682920_38	886293.Sinac_1902	1.808e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,2J3NQ@203682|Planctomycetes	203682|Planctomycetes	T	COG0745 Response regulators consisting of a CheY-like	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4682920_41	632245.CLP_4265	6.549e-20	97.0	COG1695@1|root,COG1695@2|Bacteria,1V6QJ@1239|Firmicutes,24HWE@186801|Clostridia,36ITA@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS2_k127_4682920_1	926569.ANT_19690	3.411e-165	531.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_4682920_20	1120934.KB894405_gene5593	8.866e-56	205.0	COG0566@1|root,COG0566@2|Bacteria,2GP9S@201174|Actinobacteria,4DZA9@85010|Pseudonocardiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	2.1.1.208	ko:K21514	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase
GDHHQS2_k127_4682920_45	402777.KB235903_gene2028	1.909e-16	84.0	COG2442@1|root,COG2442@2|Bacteria,1G8BK@1117|Cyanobacteria,1HCMT@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_4682920_18	667014.Thein_1148	2.28e-61	218.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_4682920_14	324602.Caur_2667	2.343e-65	230.0	COG0170@1|root,COG0170@2|Bacteria,2GBR5@200795|Chloroflexi,3767Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4682920_13	926550.CLDAP_07940	3.221e-70	255.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GDHHQS2_k127_4682920_28	926569.ANT_23660	4.86e-40	160.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS2_k127_4682920_24	926569.ANT_19420	5.2e-53	210.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GDHHQS2_k127_4682920_55	926569.ANT_19430	0.0003245	49.0	2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi	200795|Chloroflexi	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS2_k127_4682920_31	926550.CLDAP_40040	5.867e-37	146.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
GDHHQS2_k127_4682920_34	926569.ANT_19460	1.861e-29	124.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GDHHQS2_k127_4682920_11	266117.Rxyl_0101	4.992e-80	279.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_4682920_3	926550.CLDAP_40030	7.856e-144	482.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS2_k127_4682920_27	926569.ANT_19490	7.147e-42	160.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GDHHQS2_k127_4682920_54	309801.trd_1665	0.0001751	53.0	COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS2_k127_4682920_15	1118054.CAGW01000031_gene847	2.862e-65	250.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS2_k127_4682920_4	926569.ANT_01400	5.341e-137	446.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_4682920_2	926550.CLDAP_11060	5.202e-146	468.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_4682920_16	886377.Murru_1453	1.289e-64	233.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS2_k127_4682920_17	215803.DB30_3345	2.585e-64	230.0	COG4886@1|root,COG4886@2|Bacteria,1PEHG@1224|Proteobacteria,43AB5@68525|delta/epsilon subdivisions,2WX27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
GDHHQS2_k127_4682920_5	435908.IDSA_01320	5.483e-113	387.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QEYF@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS2_k127_474121_14	765420.OSCT_1835	4.688e-15	88.0	COG0823@1|root,COG1075@1|root,COG0823@2|Bacteria,COG1075@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_474121_13	926550.CLDAP_04620	1.916e-15	90.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	CP_0155	-	-	ko:K12204	-	-	-	-	ko00000,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,T4SS_TraI
GDHHQS2_k127_474121_12	1229780.BN381_330074	2.156e-25	115.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,3UX4U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GDHHQS2_k127_474121_11	590998.Celf_2156	7.611e-28	119.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4F0EH@85016|Cellulomonadaceae	201174|Actinobacteria	CJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GDHHQS2_k127_474121_15	1123070.KB899250_gene464	8.053e-12	78.0	COG0739@1|root,COG0739@2|Bacteria,46VAI@74201|Verrucomicrobia,2IU93@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_474121_16	765420.OSCT_1540	1.353e-07	64.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria,2G8N3@200795|Chloroflexi,3757D@32061|Chloroflexia	32061|Chloroflexia	MT	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_474121_18	926569.ANT_31290	0.0002558	53.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
GDHHQS2_k127_474121_0	497965.Cyan7822_1196	4.444e-202	639.0	COG1690@1|root,COG1690@2|Bacteria,1G0YE@1117|Cyanobacteria,3KJTQ@43988|Cyanothece	1117|Cyanobacteria	H	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GDHHQS2_k127_474121_1	926550.CLDAP_22540	3.764e-145	469.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS2_k127_474121_6	1123228.AUIH01000017_gene3643	9.887e-77	265.0	COG0030@1|root,COG0030@2|Bacteria,1QWDE@1224|Proteobacteria,1T5TK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS2_k127_474121_5	357808.RoseRS_4628	2.163e-83	289.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi,374T0@32061|Chloroflexia	32061|Chloroflexia	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS2_k127_474121_10	926569.ANT_31280	2.776e-40	156.0	COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
GDHHQS2_k127_474121_9	1385935.N836_28980	4.738e-46	176.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_474121_3	868131.MSWAN_0806	1.404e-93	317.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GDHHQS2_k127_474121_2	316274.Haur_1681	1.237e-103	353.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi,3759N@32061|Chloroflexia	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS2_k127_474121_4	861299.J421_4401	7.418e-88	310.0	COG5267@1|root,COG5267@2|Bacteria,1ZTEN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS2_k127_474121_8	316274.Haur_2170	2.194e-56	213.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GDHHQS2_k127_474121_7	316274.Haur_2171	1.049e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi,376D3@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4742223_15	926569.ANT_30130	1.107e-38	157.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_4742223_13	926569.ANT_30130	1.309e-45	179.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_4742223_25	351627.Csac_0414	4.433e-06	51.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia,42GZ7@68295|Thermoanaerobacterales	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_4742223_7	1429916.X566_00390	5.138e-90	301.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2TQZQ@28211|Alphaproteobacteria,3JR2M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_4742223_19	118173.KB235914_gene2494	6.051e-15	78.0	2DVDD@1|root,32UZ7@2|Bacteria,1GAMG@1117|Cyanobacteria,1HGSF@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
GDHHQS2_k127_4742223_11	644966.Tmar_1560	3.921e-61	213.0	COG4633@1|root,COG4633@2|Bacteria,1VBB8@1239|Firmicutes	1239|Firmicutes	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GDHHQS2_k127_4742223_0	644966.Tmar_1561	0.0	1050.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WCCN@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_4742223_14	593907.Celgi_0264	1.905e-39	154.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_4742223_18	1278308.KB907076_gene1505	7.429e-16	86.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4FM8H@85023|Microbacteriaceae	201174|Actinobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_4742223_17	316274.Haur_1222	8.627e-19	98.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	6.6.1.2	ko:K04748,ko:K09882	ko00860,ko01100,map00860,map01100	-	R00294,R05227	RC02000,RC02794	ko00000,ko00001,ko01000	3.D.4.10	-	-	AAA_5,CbbQ_C
GDHHQS2_k127_4742223_21	1254432.SCE1572_46990	1.994e-13	72.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS2_k127_4742223_26	935567.JAES01000029_gene2759	4.721e-06	57.0	2ASN4@1|root,31I2V@2|Bacteria,1QFS0@1224|Proteobacteria,1TD1J@1236|Gammaproteobacteria,1X9WY@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4742223_4	926560.KE387025_gene3982	2.778e-110	363.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_4742223_9	926560.KE387025_gene3981	8.6e-70	250.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_4742223_8	926560.KE387025_gene3980	1.474e-84	293.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_4742223_20	555088.DealDRAFT_1800	5.015e-14	76.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24G53@186801|Clostridia,42JVS@68298|Syntrophomonadaceae	186801|Clostridia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4742223_22	1236973.JCM9157_2253	5.324e-09	64.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4742223_12	1166018.FAES_pFAES01115	4.643e-47	174.0	COG3544@1|root,COG3544@2|Bacteria,4NM7E@976|Bacteroidetes,47QEE@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS2_k127_4742223_23	1121396.KB893072_gene1255	1.163e-07	55.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2MKA1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
GDHHQS2_k127_4742223_10	926549.KI421517_gene1458	3.168e-67	239.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_4742223_24	266117.Rxyl_2902	2.733e-06	55.0	2EKKQ@1|root,33EAI@2|Bacteria,2H1EK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4742223_1	485913.Krac_6032	2.298e-178	585.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GDHHQS2_k127_4742223_6	485913.Krac_9643	8.028e-91	304.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_4742223_5	195253.Syn6312_2647	4.458e-95	325.0	COG0642@1|root,COG0745@1|root,COG2208@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria,1GZ7I@1129|Synechococcus	1117|Cyanobacteria	T	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HisKA,Response_reg,SpoIIE
GDHHQS2_k127_4742223_16	1238182.C882_0308	1.312e-34	135.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U76I@28211|Alphaproteobacteria,2JXKZ@204441|Rhodospirillales	204441|Rhodospirillales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4742223_3	1040986.ATYO01000012_gene5293	2.344e-136	484.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS2_k127_4742223_2	1121377.KB906404_gene2877	8.878e-139	462.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_474434_37	1122214.AQWH01000001_gene583	4.439e-28	121.0	COG1609@1|root,COG1609@2|Bacteria,1R990@1224|Proteobacteria,2U51I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
GDHHQS2_k127_474434_25	1047013.AQSP01000140_gene2448	9.012e-63	227.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,4.1.3.34	ko:K01647,ko:K15234	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R00351,R00354	RC00004,RC00067,RC00502	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_474434_1	234267.Acid_3099	2.06e-248	779.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS2_k127_474434_34	1499967.BAYZ01000041_gene2366	7.733e-38	147.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cupin_2
GDHHQS2_k127_474434_16	1123277.KB893190_gene4905	2.007e-94	322.0	COG1063@1|root,COG1063@2|Bacteria,4NEDC@976|Bacteroidetes,47NXQ@768503|Cytophagia	976|Bacteroidetes	E	Threonine dehydrogenase and related Zn-dependent	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_474434_2	234267.Acid_3101	1.864e-224	704.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS2_k127_474434_30	1313172.YM304_07100	2.027e-49	179.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CN58@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GDHHQS2_k127_474434_50	1382306.JNIM01000001_gene1202	5.495e-05	48.0	COG1062@1|root,COG1062@2|Bacteria,2GBGS@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS2_k127_474434_12	189753.AXAS01000047_gene81	9.695e-118	391.0	COG0683@1|root,COG0683@2|Bacteria,1N3V5@1224|Proteobacteria,2U1KS@28211|Alphaproteobacteria,3JTNI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS2_k127_474434_15	1122218.KB893654_gene2670	2.942e-96	323.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,1JX1Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	MA20_22600	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_474434_17	935261.JAGL01000020_gene409	2.608e-90	308.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT64@28211|Alphaproteobacteria,43KX8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_22605	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS2_k127_474434_22	1144310.PMI07_005598	5.619e-83	282.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TUQB@28211|Alphaproteobacteria,4BA11@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	MA20_22610	GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS2_k127_474434_21	1411123.JQNH01000001_gene1938	4.102e-83	282.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	branched-chain amino acid	MA20_22615	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS2_k127_474434_27	706587.Desti_1326	3.642e-60	218.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WMGU@28221|Deltaproteobacteria,2MRP9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
GDHHQS2_k127_474434_41	1304874.JAFY01000005_gene1612	5.286e-23	111.0	COG0697@1|root,COG0697@2|Bacteria,3TAVN@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_474434_48	88036.EFJ17998	3.167e-06	59.0	COG1357@1|root,2QQA1@2759|Eukaryota,37KZE@33090|Viridiplantae,3G8GB@35493|Streptophyta	35493|Streptophyta	S	thylakoid lumenal 15 kDa protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009543,GO:0009579,GO:0016020,GO:0031976,GO:0031977,GO:0031978,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_474434_13	926550.CLDAP_37010	1.414e-106	351.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS2_k127_474434_10	926560.KE387023_gene3326	1.145e-123	411.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
GDHHQS2_k127_474434_43	1158050.KB895452_gene691	4.605e-18	89.0	2B3CQ@1|root,347XZ@2|Bacteria,2H7B4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_474434_11	316274.Haur_0047	2.142e-123	410.0	COG3552@1|root,COG3552@2|Bacteria,2G60I@200795|Chloroflexi,3757T@32061|Chloroflexia	32061|Chloroflexia	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
GDHHQS2_k127_474434_39	65093.PCC7418_1385	2.101e-24	104.0	COG1724@1|root,COG1724@2|Bacteria,1G7S1@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_474434_42	864702.OsccyDRAFT_2681	5.09e-19	88.0	COG1598@1|root,COG1598@2|Bacteria,1G7N4@1117|Cyanobacteria,1HDCI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS2_k127_474434_40	323848.Nmul_A2249	4.033e-24	103.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,373H6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS2_k127_474434_28	404589.Anae109_2816	6.154e-59	214.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_474434_23	1173027.Mic7113_0764	1.038e-71	246.0	COG4636@1|root,COG4636@2|Bacteria,1G58J@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_474434_7	326427.Cagg_0759	7.967e-139	448.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,374WI@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GDHHQS2_k127_474434_47	309800.C498_10596	4.184e-10	72.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GDHHQS2_k127_474434_46	926569.ANT_22940	1.712e-11	65.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS2_k127_474434_49	443906.CMM_2977	3.644e-06	54.0	COG0594@1|root,COG0594@2|Bacteria,2HY6W@201174|Actinobacteria,4FQAQ@85023|Microbacteriaceae	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS2_k127_474434_36	997346.HMPREF9374_2513	2.255e-31	126.0	COG0759@1|root,COG0759@2|Bacteria,1UEB1@1239|Firmicutes,4I3UQ@91061|Bacilli,27D7Y@186824|Thermoactinomycetaceae	91061|Bacilli	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
GDHHQS2_k127_474434_38	1220534.B655_2185	1.839e-26	124.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23PZ1@183925|Methanobacteria	183925|Methanobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GDHHQS2_k127_474434_32	573370.DMR_14800	5.134e-40	159.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2M8RK@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS2_k127_474434_31	926550.CLDAP_04280	6.128e-44	170.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GDHHQS2_k127_474434_29	926569.ANT_13990	1.125e-56	207.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS2_k127_474434_9	926550.CLDAP_06530	6.567e-124	409.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GDHHQS2_k127_474434_8	926569.ANT_13960	1.958e-127	426.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS2_k127_474434_26	1278073.MYSTI_03644	1.056e-62	226.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS2_k127_474434_24	1278073.MYSTI_03644	1.48e-63	229.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS2_k127_474434_45	552811.Dehly_0073	9.21e-15	87.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,2G9II@200795|Chloroflexi	2|Bacteria	S	Fibronectin type 3 domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Cadherin-like,Glyco_hydro_10,SLH
GDHHQS2_k127_474434_20	204669.Acid345_1547	9.192e-88	304.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria,2JMMW@204432|Acidobacteriia	204432|Acidobacteriia	L	IMS family HHH motif	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS2_k127_474434_4	720554.Clocl_1247	3.506e-163	519.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,24QZG@186801|Clostridia,3WM7X@541000|Ruminococcaceae	186801|Clostridia	M	NAD(P)H-binding	-	-	1.1.1.219,1.1.1.412	ko:K00091,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS2_k127_474434_33	926569.ANT_28940	5.542e-38	154.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS2_k127_474434_18	459349.CLOAM1343	8.614e-90	319.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS2_k127_474434_6	886293.Sinac_3058	4.896e-148	483.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS2_k127_474434_0	1128421.JAGA01000004_gene2619	1.143e-253	807.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2NQHU@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
GDHHQS2_k127_474434_3	1128421.JAGA01000002_gene789	1.343e-213	694.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2NPET@2323|unclassified Bacteria	2|Bacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GDHHQS2_k127_474434_5	1128421.JAGA01000004_gene2618	1.013e-150	491.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS2_k127_474434_19	1463841.JOIR01000025_gene199	9.797e-90	304.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria	201174|Actinobacteria	S	Neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS2_k127_474434_44	743718.Isova_0208	7.939e-15	81.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria,4F4XG@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_474434_14	1210908.HSB1_44850	1.115e-97	329.0	COG1028@1|root,arCOG01264@2157|Archaea,2XTEK@28890|Euryarchaeota,23SJP@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	sdr2	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_4830306_3	1380355.JNIJ01000001_gene3896	1.565e-71	250.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3JUE4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	MA20_28765	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GDHHQS2_k127_4830306_5	448385.sce2686	1.638e-36	153.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
GDHHQS2_k127_4830306_2	926569.ANT_07480	3.582e-85	294.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS2_k127_4830306_4	926569.ANT_07490	4.816e-71	248.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS2_k127_4830306_6	1382356.JQMP01000001_gene1162	6.881e-14	78.0	COG1525@1|root,COG1525@2|Bacteria,2GB5G@200795|Chloroflexi,27Z81@189775|Thermomicrobia	189775|Thermomicrobia	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
GDHHQS2_k127_4830306_0	309799.DICTH_0781	2.694e-111	374.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS2_k127_4830306_1	1267535.KB906767_gene4720	3.717e-107	367.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
GDHHQS2_k127_4850185_89	929562.Emtol_3724	0.0001591	47.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,47YE8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_91	710686.Mycsm_06417	0.0009364	51.0	2BF6E@1|root,328YT@2|Bacteria,2H09G@201174|Actinobacteria,23DFR@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_14	439235.Dalk_0098	3.954e-111	364.0	COG0500@1|root,COG2226@2|Bacteria,1R9JW@1224|Proteobacteria,42M76@68525|delta/epsilon subdivisions,2WK4P@28221|Deltaproteobacteria,2MPDX@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
GDHHQS2_k127_4850185_11	1396141.BATP01000044_gene1481	2.011e-114	381.0	COG4941@1|root,COG4941@2|Bacteria,46SEY@74201|Verrucomicrobia,2IV8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
GDHHQS2_k127_4850185_69	379066.GAU_3124	1.777e-21	98.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
GDHHQS2_k127_4850185_36	1120948.KB903219_gene741	9.149e-63	244.0	COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_4	102125.Xen7305DRAFT_00036370	4.144e-143	463.0	COG0075@1|root,COG0075@2|Bacteria,1G2P6@1117|Cyanobacteria,3VJFS@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class-V	spt	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
GDHHQS2_k127_4850185_21	926569.ANT_29640	1.392e-90	307.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS2_k127_4850185_17	357808.RoseRS_3898	4.044e-106	353.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS2_k127_4850185_51	316067.Geob_2523	1.164e-44	165.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
GDHHQS2_k127_4850185_13	316274.Haur_0259	1.496e-112	373.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
GDHHQS2_k127_4850185_20	316274.Haur_0258	5.117e-92	310.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
GDHHQS2_k127_4850185_35	1128421.JAGA01000001_gene2452	1.052e-68	242.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
GDHHQS2_k127_4850185_5	316274.Haur_0260	1.614e-136	456.0	COG0589@1|root,COG3842@1|root,COG0589@2|Bacteria,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,3758E@32061|Chloroflexia	2|Bacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
GDHHQS2_k127_4850185_15	68570.DC74_564	4.616e-111	369.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS2_k127_4850185_75	926550.CLDAP_08050	5.487e-17	90.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GDHHQS2_k127_4850185_9	357808.RoseRS_3212	1.936e-126	415.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GDHHQS2_k127_4850185_12	1123508.JH636449_gene7420	2.052e-113	387.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
GDHHQS2_k127_4850185_39	338966.Ppro_3011	3.409e-58	207.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,43CDX@68525|delta/epsilon subdivisions,2X7PU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4850185_28	269799.Gmet_2818	1.923e-76	291.0	COG0784@1|root,COG2202@1|root,COG2208@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1NC9X@1224|Proteobacteria,43C4D@68525|delta/epsilon subdivisions,2X7EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domains REC, PAS, PAS, PP2C	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_9,Response_reg,SpoIIE
GDHHQS2_k127_4850185_45	1408473.JHXO01000008_gene2887	2.471e-51	210.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2G153@200643|Bacteroidia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
GDHHQS2_k127_4850185_42	1128427.KB904821_gene2484	4.922e-55	207.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
GDHHQS2_k127_4850185_61	543632.JOJL01000004_gene4319	4.373e-32	138.0	COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria,4DEWX@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_4850185_54	1121015.N789_12055	6.981e-43	168.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria	1224|Proteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
GDHHQS2_k127_4850185_16	525904.Tter_0079	6.095e-108	368.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	GshA,SecD_SecF,Sec_GG
GDHHQS2_k127_4850185_31	926550.CLDAP_01790	8.982e-73	256.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS2_k127_4850185_3	349124.Hhal_1500	4.979e-146	486.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS2_k127_4850185_71	1089545.KB913037_gene2071	1.146e-19	98.0	COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria,4DYAX@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,LysM,PG_binding_1
GDHHQS2_k127_4850185_6	324602.Caur_0607	1.105e-133	446.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
GDHHQS2_k127_4850185_79	515635.Dtur_1406	3.837e-15	87.0	COG1284@1|root,COG1284@2|Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
GDHHQS2_k127_4850185_44	1128421.JAGA01000003_gene3171	9.929e-52	197.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
GDHHQS2_k127_4850185_58	680198.SCAB_23781	1.546e-34	138.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS2_k127_4850185_59	999547.KI421500_gene1299	2.18e-32	132.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GDHHQS2_k127_4850185_2	926569.ANT_14860	9.631e-157	505.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GDHHQS2_k127_4850185_24	485913.Krac_4939	1.636e-86	293.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS2_k127_4850185_8	525904.Tter_1312	6.128e-127	411.0	COG2897@1|root,COG2897@2|Bacteria,2NP8T@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS2_k127_4850185_90	1127131.WEISSC39_07550	0.0005251	48.0	COG3238@1|root,COG3238@2|Bacteria,1V0FB@1239|Firmicutes,4HFG7@91061|Bacilli,4AX8F@81850|Leuconostocaceae	91061|Bacilli	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
GDHHQS2_k127_4850185_81	391612.CY0110_13938	1.134e-13	74.0	COG4679@1|root,COG4679@2|Bacteria,1G6SB@1117|Cyanobacteria	1117|Cyanobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS2_k127_4850185_78	635013.TherJR_1621	8.643e-16	83.0	COG3620@1|root,COG3620@2|Bacteria,1VH02@1239|Firmicutes,24RIF@186801|Clostridia,262X9@186807|Peptococcaceae	186801|Clostridia	K	PFAM helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS2_k127_4850185_25	1382356.JQMP01000003_gene2195	1.867e-82	281.0	COG1116@1|root,COG1116@2|Bacteria,2G6BU@200795|Chloroflexi,27YRQ@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_4850185_19	926569.ANT_09480	6.727e-99	338.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GDHHQS2_k127_4850185_50	639030.JHVA01000001_gene2552	4.266e-45	174.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS2_k127_4850185_23	497965.Cyan7822_4382	1.539e-89	304.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,3KG4M@43988|Cyanothece	1117|Cyanobacteria	C	Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
GDHHQS2_k127_4850185_88	345219.Bcoa_2890	9.419e-05	55.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus	91061|Bacilli	M	Glycoside Hydrolase Family	yaaH_2	-	-	ko:K06306	-	-	-	-	ko00000	-	-	-	Glyco_hydro_18,LysM
GDHHQS2_k127_4850185_57	525904.Tter_2106	1.307e-35	152.0	COG0308@1|root,COG3103@1|root,COG0308@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.4.11.2,3.4.21.96	ko:K01256,ko:K01361	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_MA_2,SH3_3,SpoIID
GDHHQS2_k127_4850185_34	243231.GSU2483	1.683e-70	257.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
GDHHQS2_k127_4850185_33	765420.OSCT_0418	1.331e-70	245.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_4850185_80	926550.CLDAP_27830	8.638e-15	87.0	2DM58@1|root,31S4C@2|Bacteria,2GBK4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_27	383372.Rcas_2940	7.877e-80	277.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi,37696@32061|Chloroflexia	32061|Chloroflexia	O	PFAM heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS2_k127_4850185_87	69395.JQLZ01000001_gene3204	9.652e-06	51.0	2DJBU@1|root,32UCQ@2|Bacteria,1N6AP@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS2_k127_4850185_70	926569.ANT_08490	1.838e-21	102.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS2_k127_4850185_64	1343740.M271_06050	4.748e-27	119.0	COG3271@1|root,COG3271@2|Bacteria,2HJXD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GDHHQS2_k127_4850185_86	369723.Strop_2362	8.94e-08	63.0	2DUQ4@1|root,33RP2@2|Bacteria,2IKP9@201174|Actinobacteria,4DE39@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_10	1242864.D187_000739	7.325e-124	404.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,42QSZ@68525|delta/epsilon subdivisions,2WN50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
GDHHQS2_k127_4850185_26	351160.RCIX1096	6.524e-81	284.0	arCOG11014@1|root,arCOG11014@2157|Archaea,2XZ0A@28890|Euryarchaeota,2NB35@224756|Methanomicrobia	224756|Methanomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GDHHQS2_k127_4850185_40	5180.EDO03054	4.195e-58	215.0	KOG0272@1|root,KOG0295@1|root,KOG0272@2759|Eukaryota,KOG0295@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM8R@4890|Ascomycota	4751|Fungi	A	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,WD40
GDHHQS2_k127_4850185_46	1121926.AXWO01000017_gene3037	1.707e-48	181.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4EYZM@85014|Glycomycetales	201174|Actinobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
GDHHQS2_k127_4850185_74	1144275.COCOR_01560	4.787e-18	89.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4850185_68	289376.THEYE_A1338	3.277e-23	105.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4850185_37	1304874.JAFY01000002_gene352	2.509e-61	234.0	COG0642@1|root,COG2205@2|Bacteria	1304874.JAFY01000002_gene352|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_77	395961.Cyan7425_0748	7.167e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_4850185_67	289376.THEYE_A1338	2.994e-23	103.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS2_k127_4850185_38	1123267.JONN01000002_gene279	5.979e-60	227.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,2TX5S@28211|Alphaproteobacteria,2KEH3@204457|Sphingomonadales	204457|Sphingomonadales	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_4850185_29	489825.LYNGBM3L_54460	1.333e-75	265.0	COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales	1117|Cyanobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GDHHQS2_k127_4850185_65	926569.ANT_23580	1.755e-26	117.0	COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi	200795|Chloroflexi	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GDHHQS2_k127_4850185_84	382464.ABSI01000006_gene771	4.082e-11	73.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ybgC-2	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
GDHHQS2_k127_4850185_48	981369.JQMJ01000004_gene4665	2.367e-47	181.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	yugF	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_4850185_22	926560.KE387023_gene2647	9.843e-90	304.0	COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_55	991.IW20_12415	2.568e-37	144.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1I4HD@117743|Flavobacteriia,2NW8P@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_4850185_60	1236976.JCM16418_2883	2.652e-32	132.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_4850185_49	1237149.C900_00974	1.527e-45	168.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_4850185_63	390989.JOEG01000033_gene1578	9.58e-28	120.0	COG0454@1|root,COG0456@2|Bacteria,2GPVC@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_4850185_43	485913.Krac_3678	2.248e-54	194.0	COG1720@1|root,COG1720@2|Bacteria,2G799@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GDHHQS2_k127_4850185_73	886293.Sinac_4103	1.554e-19	93.0	296Z1@1|root,2ZU7K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4850185_32	1382306.JNIM01000001_gene146	2.595e-72	255.0	COG0613@1|root,COG0613@2|Bacteria,2G71S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GDHHQS2_k127_4850185_18	240292.Ava_C0001	5.865e-105	357.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1HKQS@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS2_k127_4850185_72	649831.L083_4234	1.469e-19	97.0	COG0640@1|root,COG0640@2|Bacteria,2GQ1F@201174|Actinobacteria,4DF31@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS2_k127_4850185_1	1121468.AUBR01000034_gene1374	7.033e-157	513.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_4850185_85	118173.KB235914_gene1451	2.764e-10	72.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,PepSY,RicinB_lectin_2,Ricin_B_lectin,SLH
GDHHQS2_k127_4850185_0	693661.Arcve_0328	4.794e-256	803.0	COG0365@1|root,arCOG01529@2157|Archaea,2XTAB@28890|Euryarchaeota,246QT@183980|Archaeoglobi	183980|Archaeoglobi	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS2_k127_4850185_56	1185876.BN8_04387	2.855e-36	154.0	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
GDHHQS2_k127_4850185_52	404589.Anae109_2549	3.19e-44	166.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WRZW@28221|Deltaproteobacteria,2YWS5@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GDHHQS2_k127_4850185_53	292459.STH494	1.503e-43	168.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS2_k127_4850185_41	485913.Krac_11761	3.078e-55	201.0	COG0639@1|root,COG0639@2|Bacteria,2G8J5@200795|Chloroflexi	200795|Chloroflexi	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_4850185_7	1382356.JQMP01000001_gene1074	4.442e-130	426.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS2_k127_4850185_30	875328.JDM601_1645	5.034e-73	251.0	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_4850185_47	55952.BU52_16990	7.693e-48	181.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GDHHQS2_k127_4850185_82	509635.N824_28775	2.642e-12	78.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1IPWE@117747|Sphingobacteriia	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
GDHHQS2_k127_4850185_66	497964.CfE428DRAFT_3727	2.045e-23	108.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
GDHHQS2_k127_4850185_62	1150621.SMUL_1513	9.975e-32	131.0	2CCY9@1|root,32W6X@2|Bacteria,1N3DH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4874140_19	485913.Krac_6551	2.076e-07	56.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
GDHHQS2_k127_4874140_2	926692.AZYG01000085_gene856	1.301e-90	308.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
GDHHQS2_k127_4874140_7	1265505.ATUG01000001_gene4101	4.662e-37	160.0	COG3209@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2MIDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
GDHHQS2_k127_4874140_16	28258.KP05_13765	3.622e-11	76.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,1XHEX@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GDHHQS2_k127_4874140_1	1196322.A370_00418	2.198e-101	350.0	COG0476@1|root,COG0476@2|Bacteria,1VIBM@1239|Firmicutes,25GG8@186801|Clostridia,36WX5@31979|Clostridiaceae	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
GDHHQS2_k127_4874140_6	326424.FRAAL0854	2.966e-38	155.0	COG5078@1|root,COG5078@2|Bacteria	2|Bacteria	O	protein modification by small protein conjugation	-	-	-	-	-	-	-	-	-	-	-	-	ThiF,UQ_con,Yop-YscD_cpl
GDHHQS2_k127_4874140_12	326424.FRAAL0857	3.999e-19	90.0	2EFHE@1|root,3399Z@2|Bacteria	2|Bacteria	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
GDHHQS2_k127_4874140_11	1408324.JNJK01000013_gene63	6.691e-24	114.0	COG1310@1|root,COG1310@2|Bacteria,1VQJE@1239|Firmicutes,24CU8@186801|Clostridia	186801|Clostridia	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	JAB,LysM
GDHHQS2_k127_4874140_10	575540.Isop_1343	8.978e-25	113.0	COG1310@1|root,COG1310@2|Bacteria,2IZZW@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Mov34 MPN PAD-1 family	-	-	-	-	-	-	-	-	-	-	-	-	JAB
GDHHQS2_k127_4874140_20	278963.ATWD01000001_gene4674	3.537e-06	58.0	COG1716@1|root,COG1716@2|Bacteria,3Y6SP@57723|Acidobacteria,2JKXP@204432|Acidobacteriia	204432|Acidobacteriia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4874140_9	293826.Amet_1755	1.636e-27	126.0	COG2304@1|root,COG2304@2|Bacteria,1U8R5@1239|Firmicutes,24F1T@186801|Clostridia,36PN4@31979|Clostridiaceae	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
GDHHQS2_k127_4874140_14	1347086.CCBA010000027_gene3390	9.141e-16	79.0	2EGSG@1|root,33AIJ@2|Bacteria,1VMPG@1239|Firmicutes,4HRBP@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4874140_5	268407.PWYN_13690	1.917e-39	151.0	COG4430@1|root,COG4430@2|Bacteria,1TYVP@1239|Firmicutes,4I0UE@91061|Bacilli,26YIC@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
GDHHQS2_k127_4874140_18	345341.KUTG_06355	3.826e-09	63.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,4E3VU@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS2_k127_4874140_4	1134413.ANNK01000134_gene3113	3.161e-57	205.0	28PN2@1|root,2ZCAV@2|Bacteria,1V2C1@1239|Firmicutes,4HGS6@91061|Bacilli,1ZG8V@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_4874140_8	926569.ANT_26490	1.96e-33	142.0	COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
GDHHQS2_k127_4874140_3	926569.ANT_14140	6.778e-80	274.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS2_k127_4874140_0	926550.CLDAP_02580	2.25e-145	469.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS2_k127_4874140_17	1089550.ATTH01000001_gene750	2.512e-10	63.0	2DU0P@1|root,33NFC@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281
GDHHQS2_k127_5118504_18	357808.RoseRS_1536	3.686e-27	126.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GDHHQS2_k127_5118504_15	1382306.JNIM01000001_gene1137	8.492e-33	135.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5118504_20	867845.KI911784_gene2572	1.351e-26	122.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GDHHQS2_k127_5118504_31	1121920.AUAU01000021_gene2530	0.0009979	51.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_5118504_1	1128421.JAGA01000002_gene397	1.588e-174	558.0	COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528,iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS2_k127_5118504_30	357808.RoseRS_4120	0.0006895	50.0	COG2340@1|root,COG2340@2|Bacteria,2GBMZ@200795|Chloroflexi,3782U@32061|Chloroflexia	32061|Chloroflexia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5118504_8	525904.Tter_0227	1.003e-83	289.0	COG1171@1|root,COG1171@2|Bacteria,2NQCM@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006464,GO:0006520,GO:0006549,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008838,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0031406,GO:0032787,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.3.1.263,3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989,ko:K21400	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2699,iECED1_1282.ECED1_3331,iJN678.ilvA,iLJ478.TM0356,iNJ661.Rv1559	PALP,Thr_dehydrat_C
GDHHQS2_k127_5118504_5	671143.DAMO_0158	3.148e-119	395.0	COG4409@1|root,COG4409@2|Bacteria,2NQRQ@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GDHHQS2_k127_5118504_27	1041139.KB902691_gene743	2.273e-13	76.0	29Y2J@1|root,30JVH@2|Bacteria,1PQK7@1224|Proteobacteria,2V2Z0@28211|Alphaproteobacteria,4BEPF@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5118504_9	1122223.KB890687_gene2436	9.749e-77	261.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS2_k127_5118504_28	1240349.ANGC01000043_gene4536	1.043e-06	57.0	COG3427@1|root,COG3427@2|Bacteria,2IRE2@201174|Actinobacteria,4G3AE@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS2_k127_5118504_24	926550.CLDAP_19750	1.839e-16	84.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
GDHHQS2_k127_5118504_4	1265505.ATUG01000001_gene4318	6.579e-141	465.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS2_k127_5118504_10	926569.ANT_14920	3.225e-74	256.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS2_k127_5118504_23	1128421.JAGA01000002_gene1375	2.698e-17	82.0	COG2217@1|root,COG2217@2|Bacteria,2NNY4@2323|unclassified Bacteria	2|Bacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
GDHHQS2_k127_5118504_22	926550.CLDAP_14470	1.281e-18	87.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
GDHHQS2_k127_5118504_29	765420.OSCT_3218	0.0001516	48.0	COG0640@1|root,COG0640@2|Bacteria,2G980@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS2_k127_5118504_25	926569.ANT_21130	4.191e-15	76.0	COG0526@1|root,COG0526@2|Bacteria,2G7HI@200795|Chloroflexi	200795|Chloroflexi	CO	TIGRFAM redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GDHHQS2_k127_5118504_2	479434.Sthe_1374	5.97e-168	534.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GDHHQS2_k127_5118504_26	909663.KI867150_gene69	1.087e-14	75.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5118504_17	631454.N177_4036	3.871e-28	123.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,1JPDT@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GDHHQS2_k127_5118504_11	1304878.AUGD01000012_gene4110	6.818e-59	210.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2UIDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5118504_16	317936.Nos7107_3521	2.815e-30	125.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5118504_12	926569.ANT_04520	3.724e-54	196.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GDHHQS2_k127_5118504_6	926569.ANT_04510	1.473e-117	382.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS2_k127_5118504_3	926550.CLDAP_25810	1.871e-145	468.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS2_k127_5118504_21	635013.TherJR_1679	5.022e-19	89.0	COG1146@1|root,COG1146@2|Bacteria,1VETY@1239|Firmicutes,25E51@186801|Clostridia,2630V@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
GDHHQS2_k127_5118504_19	926569.ANT_22000	6.193e-27	117.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	-	-	3.4.23.51	ko:K00442,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	-	HycI
GDHHQS2_k127_5118504_13	926569.ANT_22010	1.195e-38	148.0	COG1143@1|root,COG1143@2|Bacteria,2G9SP@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	ko:K14091	-	-	-	-	ko00000	-	-	-	Fer4
GDHHQS2_k127_5118504_7	926569.ANT_22020	1.026e-111	368.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS2_k127_5118504_0	926569.ANT_22030	4.42e-180	571.0	COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi	200795|Chloroflexi	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
GDHHQS2_k127_5118504_14	926569.ANT_22040	5.115e-38	149.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS2_k127_5181866_2	316274.Haur_1182	8.52e-99	336.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi,375G6@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
GDHHQS2_k127_5181866_0	926569.ANT_08110	1.373e-189	602.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS2_k127_5181866_1	926569.ANT_08100	4.2e-106	351.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS2_k127_536026_3	552811.Dehly_1410	7.089e-137	451.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi,34CJB@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Telomere recombination	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GDHHQS2_k127_536026_18	1463900.JOIX01000014_gene2200	1.936e-26	110.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria	201174|Actinobacteria	O	Hydrogenase expression formation protein	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
GDHHQS2_k127_536026_0	867845.KI911784_gene3689	2.788e-153	493.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
GDHHQS2_k127_536026_2	765420.OSCT_2611	2.492e-139	452.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_536026_20	1173029.JH980292_gene614	5.371e-21	102.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GDHHQS2_k127_536026_9	448385.sce2707	1.859e-51	188.0	2E8ZQ@1|root,33397@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_17	1033810.HLPCO_002204	3.19e-27	117.0	2C3U1@1|root,32RCS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_6	293826.Amet_4279	1.779e-66	237.0	COG1266@1|root,COG1266@2|Bacteria,1V1I8@1239|Firmicutes,24EXX@186801|Clostridia,36IEW@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS2_k127_536026_12	1114856.C496_09266	1.344e-41	164.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_536026_7	641491.DND132_1020	1.062e-58	214.0	COG1266@1|root,COG1266@2|Bacteria,1PD7P@1224|Proteobacteria,435PI@68525|delta/epsilon subdivisions,2X03C@28221|Deltaproteobacteria,2MA9B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_536026_11	1033810.HLPCO_001863	9.804e-43	166.0	2EHEG@1|root,33B6E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_536026_5	1120949.KB903329_gene9217	1.892e-122	425.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
GDHHQS2_k127_536026_15	547559.Nmag_4079	3.527e-32	136.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_536026_19	867845.KI911784_gene122	4.99e-25	118.0	COG1266@1|root,COG1266@2|Bacteria,2G912@200795|Chloroflexi,377V6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_536026_8	1122143.AUEG01000001_gene499	1.406e-54	196.0	2B4YW@1|root,31XRX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_14	1206744.BAGL01000128_gene6768	1.019e-35	146.0	COG3832@1|root,COG3832@2|Bacteria,2IBWM@201174|Actinobacteria,4G90C@85025|Nocardiaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_10	1347086.CCBA010000011_gene1498	6.476e-51	192.0	2CBE1@1|root,32RT5@2|Bacteria,1UPX9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_22	498211.CJA_1996	1.107e-10	68.0	2BQ62@1|root,32J0I@2|Bacteria,1QSS2@1224|Proteobacteria,1RWAF@1236|Gammaproteobacteria,1FHKA@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_536026_23	641491.DND132_2968	1.093e-08	59.0	COG3462@1|root,COG3462@2|Bacteria,1QE33@1224|Proteobacteria,43EKD@68525|delta/epsilon subdivisions,2X0Z4@28221|Deltaproteobacteria,2MDTR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GDHHQS2_k127_536026_21	869210.Marky_1036	1.617e-16	80.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS2_k127_536026_16	479434.Sthe_2174	3.269e-31	129.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_536026_13	644548.SCNU_07533	7.826e-39	152.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4GDUK@85026|Gordoniaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GDHHQS2_k127_536026_4	926569.ANT_06990	2.599e-135	447.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GDHHQS2_k127_536026_1	926569.ANT_06990	4.271e-152	496.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GDHHQS2_k127_536026_24	1461580.CCAS010000015_gene1842	2.827e-07	53.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5540946_3	926569.ANT_08370	1.066e-65	226.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS2_k127_5540946_5	324602.Caur_2905	1.027e-38	151.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,375QH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS2_k127_5540946_6	357808.RoseRS_2233	6.324e-35	136.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia	32061|Chloroflexia	F	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS2_k127_5540946_4	941449.dsx2_1650	7.371e-54	191.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2MCQP@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_5540946_0	1128421.JAGA01000002_gene149	6.8e-157	522.0	COG1009@1|root,COG1009@2|Bacteria,2NNU6@2323|unclassified Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00341,ko:K12137	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945	Proton_antipo_M,Proton_antipo_N
GDHHQS2_k127_5540946_1	926550.CLDAP_08660	2.155e-154	502.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS2_k127_5540946_2	926569.ANT_08420	4.011e-116	391.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS2_k127_572764_40	439235.Dalk_3544	0.0004348	53.0	29RQM@1|root,30CU4@2|Bacteria,1NU3F@1224|Proteobacteria,42YUA@68525|delta/epsilon subdivisions,2WUNP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_32	356851.JOAN01000003_gene1447	3.013e-09	66.0	2B2ME@1|root,31V6U@2|Bacteria,2IIMI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
GDHHQS2_k127_572764_23	476272.RUMHYD_01471	3.323e-32	144.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,3XZP2@572511|Blautia	186801|Clostridia	S	phage phi-C31 gp36 major capsid-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
GDHHQS2_k127_572764_35	1114964.L485_00145	1.693e-05	57.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,2JZVE@204457|Sphingomonadales	204457|Sphingomonadales	S	portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
GDHHQS2_k127_572764_7	1120971.AUCA01000049_gene794	2.516e-68	249.0	COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_572764_34	640081.Dsui_0192	3.367e-08	59.0	2DNPG@1|root,32YEX@2|Bacteria,1N9QI@1224|Proteobacteria,2W4WW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_5	1267005.KB911256_gene1853	3.172e-74	255.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,3N8E7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_572764_10	582899.Hden_3523	1.117e-61	218.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,3N8E7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_572764_12	485913.Krac_0968	3.432e-52	192.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
GDHHQS2_k127_572764_14	1459636.NTE_02189	3.763e-45	169.0	COG0262@1|root,arCOG01490@2157|Archaea	2157|Archaea	H	Belongs to the dihydrofolate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_572764_22	383372.Rcas_2235	1.392e-32	134.0	2EKJA@1|root,313YA@2|Bacteria,2GAJ9@200795|Chloroflexi,376HE@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_29	525368.HMPREF0591_6369	1.145e-15	83.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,238KG@1762|Mycobacteriaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
GDHHQS2_k127_572764_17	1173024.KI912149_gene5559	3.857e-39	153.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1JM95@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS2_k127_572764_31	1128427.KB904821_gene4403	1.458e-09	68.0	COG1357@1|root,COG1357@2|Bacteria,1G45P@1117|Cyanobacteria,1HAMW@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_572764_9	926550.CLDAP_00710	2.753e-66	233.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_572764_30	195250.CM001776_gene1579	3.825e-12	76.0	2E8GM@1|root,332UW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_38	1215915.BN193_01240	0.0001709	52.0	29XCX@1|root,30J2U@2|Bacteria,1UVKE@1239|Firmicutes,4I2BF@91061|Bacilli,1YCNH@1357|Lactococcus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_11	65497.JODV01000021_gene2136	1.285e-56	203.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4E351@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_572764_3	1218084.BBJK01000002_gene216	3.195e-118	392.0	COG0654@1|root,COG0654@2|Bacteria,1R7NX@1224|Proteobacteria,2WIBD@28216|Betaproteobacteria,1KB40@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GDHHQS2_k127_572764_27	68194.JNXR01000004_gene4565	2.958e-17	94.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_572764_4	1382306.JNIM01000001_gene910	2.501e-103	346.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_572764_24	1382356.JQMP01000003_gene2103	7.719e-22	102.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,27XY0@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_572764_13	1122915.AUGY01000001_gene7175	6.47e-50	182.0	COG4275@1|root,COG4275@2|Bacteria,1VNZY@1239|Firmicutes	1239|Firmicutes	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS2_k127_572764_20	1122915.AUGY01000001_gene7174	2.276e-36	142.0	COG4275@1|root,COG4275@2|Bacteria,1V6T7@1239|Firmicutes	1239|Firmicutes	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_8	1121920.AUAU01000025_gene2333	6.694e-67	238.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
GDHHQS2_k127_572764_2	316274.Haur_4661	1.692e-129	429.0	COG0477@1|root,COG2814@2|Bacteria,2G5ZW@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_572764_36	1312954.KI914899_gene175	2.25e-05	54.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,1W8EC@1268|Micrococcaceae	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
GDHHQS2_k127_572764_26	357808.RoseRS_3459	1.494e-17	89.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,374VC@32061|Chloroflexia	32061|Chloroflexia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_572764_16	1197130.BAFM01000015_gene2443	1.818e-42	164.0	arCOG01782@1|root,arCOG01782@2157|Archaea,2XTX4@28890|Euryarchaeota,23TWF@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_572764_18	1219077.VAZ01S_105_00060	1.295e-38	156.0	COG2865@1|root,COG2865@2|Bacteria,1P3KJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_41	1242864.D187_001593	0.0004512	44.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	irrE	-	-	ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF4344,Peptidase_M78
GDHHQS2_k127_572764_21	1235279.C772_01971	3.139e-36	147.0	arCOG07807@1|root,32S82@2|Bacteria,1VE45@1239|Firmicutes,4HZ71@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_0	234267.Acid_5088	1.82e-196	625.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_572764_1	926569.ANT_21940	1.553e-168	548.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
GDHHQS2_k127_572764_15	485913.Krac_5686	2.066e-43	169.0	2ECJT@1|root,336HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_572764_19	926569.ANT_21970	1.064e-37	154.0	COG1073@1|root,COG1073@2|Bacteria,2G73I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS2_k127_572764_6	1242864.D187_009613	4.341e-72	259.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
GDHHQS2_k127_572764_25	749927.AMED_0020	1.727e-21	109.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria,4E03R@85010|Pseudonocardiales	201174|Actinobacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
GDHHQS2_k127_5735579_10	357808.RoseRS_0169	3.015e-87	294.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
GDHHQS2_k127_5735579_22	1128421.JAGA01000003_gene3084	1.911e-49	186.0	COG0619@1|root,COG0619@2|Bacteria,2NRVG@2323|unclassified Bacteria	2|Bacteria	P	PFAM Cobalt transport protein	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
GDHHQS2_k127_5735579_12	926569.ANT_12690	8.1e-80	278.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi	200795|Chloroflexi	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
GDHHQS2_k127_5735579_27	383372.Rcas_4176	7.065e-42	164.0	COG0500@1|root,COG2226@2|Bacteria,2GBRI@200795|Chloroflexi,3769K@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_5735579_52	926569.ANT_08720	1.667e-06	61.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yneA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
GDHHQS2_k127_5735579_8	926550.CLDAP_04560	3.934e-118	391.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5735579_36	208439.AJAP_20920	1.542e-17	89.0	COG1695@1|root,COG1695@2|Bacteria,2HQF6@201174|Actinobacteria,4E97Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GDHHQS2_k127_5735579_11	926569.ANT_30980	1.674e-85	291.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi	200795|Chloroflexi	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
GDHHQS2_k127_5735579_16	1128421.JAGA01000001_gene2166	1.436e-66	233.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
GDHHQS2_k127_5735579_15	926569.ANT_30990	2.94e-70	250.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K06857	ko02010,map02010	M00186,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
GDHHQS2_k127_5735579_56	1397527.Q670_16695	0.0005272	52.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,1XIYX@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GDHHQS2_k127_5735579_0	926569.ANT_04140	0.0	1173.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS2_k127_5735579_25	383372.Rcas_1313	1.693e-45	171.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS2_k127_5735579_1	472759.Nhal_2157	6.989e-280	876.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales	135613|Chromatiales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_5735579_50	489825.LYNGBM3L_32100	1.137e-07	64.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_5735579_7	926569.ANT_25450	6.047e-143	460.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GDHHQS2_k127_5735579_2	926569.ANT_02690	2.809e-240	754.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
GDHHQS2_k127_5735579_21	1121382.JQKG01000049_gene2017	4.469e-50	183.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
GDHHQS2_k127_5735579_43	240302.BN982_01197	1.134e-11	76.0	COG3153@1|root,COG3153@2|Bacteria,1V0I4@1239|Firmicutes,4HCMH@91061|Bacilli,3NDUK@45667|Halobacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
GDHHQS2_k127_5735579_13	351348.Maqu_1656	1.213e-76	265.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
GDHHQS2_k127_5735579_19	485913.Krac_0472	1.155e-55	203.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	aadD	-	-	ko:K17882	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	KNTase_C,NTP_transf_2
GDHHQS2_k127_5735579_35	1274374.CBLK010000026_gene2923	2.491e-27	127.0	COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,4HIRR@91061|Bacilli,26XW1@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_5735579_33	1121875.KB907546_gene2684	2.749e-31	127.0	COG0346@1|root,COG0346@2|Bacteria,4NQVZ@976|Bacteroidetes,1I3NG@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS2_k127_5735579_5	1254432.SCE1572_04195	1.221e-156	512.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2WQMZ@28221|Deltaproteobacteria,2YY10@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
GDHHQS2_k127_5735579_55	1168289.AJKI01000007_gene197	0.0003648	53.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,3XIM1@558415|Marinilabiliaceae	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GDHHQS2_k127_5735579_28	926569.ANT_02700	2.349e-41	160.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GDHHQS2_k127_5735579_30	479434.Sthe_3197	3.175e-36	144.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS2_k127_5735579_37	479434.Sthe_1755	3.95e-17	91.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GDHHQS2_k127_5735579_47	1385521.N803_05710	7.057e-10	66.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	COP23,Fasciclin
GDHHQS2_k127_5735579_53	1144275.COCOR_07574	4.99e-06	57.0	2AI3B@1|root,318H4@2|Bacteria,1PA8C@1224|Proteobacteria	1224|Proteobacteria	S	Immunity protein Imm5	-	-	-	-	-	-	-	-	-	-	-	-	Imm5
GDHHQS2_k127_5735579_6	1385520.N802_14030	1.522e-145	479.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS2_k127_5735579_44	1177154.Y5S_03011	1.743e-11	72.0	COG3793@1|root,COG3793@2|Bacteria,1P6XA@1224|Proteobacteria,1SV9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	zinc-ribbon family	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
GDHHQS2_k127_5735579_17	192952.MM_1056	2.838e-62	232.0	COG1668@1|root,arCOG01462@2157|Archaea,2XX4X@28890|Euryarchaeota,2NAR7@224756|Methanomicrobia	224756|Methanomicrobia	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS2_k127_5735579_14	1128421.JAGA01000003_gene3200	3.243e-74	259.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	ecsA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS2_k127_5735579_4	471852.Tcur_2494	2.292e-164	529.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_5735579_3	485913.Krac_4184	8.166e-184	578.0	COG0667@1|root,COG0667@2|Bacteria,2G7Z5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_5735579_42	1158607.UAU_01972	2.014e-15	77.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,4HC0W@91061|Bacilli,4B6G1@81852|Enterococcaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_5735579_24	1303518.CCALI_00021	8.711e-47	178.0	2EATK@1|root,334VC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5735579_23	1121924.ATWH01000001_gene4463	2.683e-47	182.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_5735579_9	1499967.BAYZ01000027_gene1768	8.962e-109	387.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,NACHT,NPCBM,PEGA,Pkinase
GDHHQS2_k127_5735579_29	1128421.JAGA01000004_gene2670	4.874e-38	146.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_5735579_20	1220534.B655_2327	2.233e-52	190.0	COG3797@1|root,arCOG08236@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS2_k127_5735579_26	518766.Rmar_1489	2.861e-44	168.0	COG4636@1|root,COG4636@2|Bacteria,4NNM9@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5735579_31	1444712.BN1013_01006	1.788e-32	132.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yokL3	-	2.3.1.57	ko:K00657,ko:K07023	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
GDHHQS2_k127_5735579_41	1463857.JOFZ01000005_gene3175	1.889e-15	83.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GDHHQS2_k127_5735579_18	1385512.N784_11270	8.13e-57	203.0	COG1670@1|root,COG1670@2|Bacteria,1V8EU@1239|Firmicutes,4HJPX@91061|Bacilli,2YBKC@289201|Pontibacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS2_k127_5735579_34	1385510.N781_16325	1.004e-28	133.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,2Y97C@289201|Pontibacillus	91061|Bacilli	E	Peptide-binding protein	oppA3	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS2_k127_5735579_45	1236976.JCM16418_1790	4.071e-10	70.0	COG0454@1|root,COG0456@2|Bacteria,1TS4G@1239|Firmicutes,4HFDG@91061|Bacilli,26XFQ@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_5735579_38	945713.IALB_1498	3.969e-17	86.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
GDHHQS2_k127_5735579_32	926560.KE387027_gene896	3.01e-32	138.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
GDHHQS2_k127_5735579_39	926560.KE387027_gene896	3.325e-16	92.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
GDHHQS2_k127_5803379_49	926569.ANT_08530	2.652e-117	385.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS2_k127_5803379_171	926569.ANT_19040	6.024e-18	89.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_85	1173025.GEI7407_2335	1.474e-80	274.0	COG2013@1|root,COG2013@2|Bacteria,1G2XX@1117|Cyanobacteria,1H9ZF@1150|Oscillatoriales	1117|Cyanobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
GDHHQS2_k127_5803379_88	357808.RoseRS_3316	1.1e-78	271.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,375ER@32061|Chloroflexia	32061|Chloroflexia	G	PFAM inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS2_k127_5803379_77	926550.CLDAP_07100	9.807e-91	305.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_5803379_177	1123508.JH636449_gene7269	3.615e-13	72.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
GDHHQS2_k127_5803379_156	1123508.JH636449_gene7269	2.316e-27	115.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
GDHHQS2_k127_5803379_33	926569.ANT_29200	7.398e-141	471.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GDHHQS2_k127_5803379_30	316274.Haur_4661	1.645e-147	479.0	COG0477@1|root,COG2814@2|Bacteria,2G5ZW@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5803379_101	926569.ANT_23120	3.26e-68	245.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS2_k127_5803379_191	562973.HMPREF0059_00949	3.087e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4D3ZA@85005|Actinomycetales	201174|Actinobacteria	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS2_k127_5803379_51	357808.RoseRS_3083	9.41e-117	392.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_5803379_37	383372.Rcas_3001	1.207e-135	441.0	COG1167@1|root,COG1167@2|Bacteria,2G81Z@200795|Chloroflexi,376VD@32061|Chloroflexia	32061|Chloroflexia	EK	PFAM aminotransferase, class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GDHHQS2_k127_5803379_96	324602.Caur_2456	2.985e-73	256.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_5803379_112	926569.ANT_06590	1.411e-56	208.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_5803379_143	926569.ANT_09090	5.823e-34	147.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
GDHHQS2_k127_5803379_152	1121430.JMLG01000038_gene2034	1.424e-29	126.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_5803379_0	1128421.JAGA01000004_gene2487	0.0	1150.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS2_k127_5803379_174	304371.MCP_2503	3.033e-16	82.0	COG1917@1|root,arCOG02999@2157|Archaea,2Y71Y@28890|Euryarchaeota,2NB48@224756|Methanomicrobia	224756|Methanomicrobia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_5803379_120	1217718.ALOU01000010_gene885	5.506e-52	192.0	COG0526@1|root,COG0526@2|Bacteria,1RA5V@1224|Proteobacteria,2VQX7@28216|Betaproteobacteria,1KFIZ@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS2_k127_5803379_160	926569.ANT_14090	4.658e-26	115.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
GDHHQS2_k127_5803379_71	926550.CLDAP_01930	1.203e-96	344.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS2_k127_5803379_13	309801.trd_A0017	9.641e-192	610.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS2_k127_5803379_180	324602.Caur_3810	2.838e-10	74.0	COG5305@1|root,COG5305@2|Bacteria,2GAHI@200795|Chloroflexi,3765S@32061|Chloroflexia	32061|Chloroflexia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_122	926560.KE387027_gene789	1.173e-50	195.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_5803379_106	1122221.JHVI01000007_gene2245	3.962e-64	228.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_5803379_147	357808.RoseRS_2612	2.21e-31	129.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi,375SZ@32061|Chloroflexia	32061|Chloroflexia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS2_k127_5803379_45	926550.CLDAP_07480	4.174e-122	405.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_5803379_66	1273538.G159_02435	3.027e-100	336.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,26DWX@186818|Planococcaceae	91061|Bacilli	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS2_k127_5803379_124	266834.SM_b21237	1.513e-49	189.0	COG4424@1|root,COG4424@2|Bacteria,1N2S4@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS2_k127_5803379_173	324602.Caur_0892	1.907e-16	88.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	pknD	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08282,ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NHL,Pkinase
GDHHQS2_k127_5803379_155	765914.ThisiDRAFT_1552	3.15e-28	124.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,Methyltransf_32
GDHHQS2_k127_5803379_140	455632.SGR_3008	2.53e-35	149.0	COG4927@1|root,COG4927@2|Bacteria,2I9GM@201174|Actinobacteria,41CYY@629295|Streptomyces griseus group	201174|Actinobacteria	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
GDHHQS2_k127_5803379_162	661478.OP10G_0003	7.334e-24	115.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_5803379_154	485913.Krac_3270	1.759e-28	128.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,PD40,Pentapeptide,Pkinase,TIR_2,WD40
GDHHQS2_k127_5803379_126	1157490.EL26_23150	1.248e-48	185.0	COG1250@1|root,COG1250@2|Bacteria,1TSZI@1239|Firmicutes,4HBK3@91061|Bacilli,279Y5@186823|Alicyclobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_5803379_68	292459.STH214	1.411e-99	332.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS2_k127_5803379_84	1207063.P24_16320	4.999e-83	283.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,2JR87@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS2_k127_5803379_74	869210.Marky_1278	2.653e-95	318.0	COG1024@1|root,COG1024@2|Bacteria,1WIV2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS2_k127_5803379_168	1356854.N007_19530	1.73e-19	95.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes,4HJC6@91061|Bacilli,27A2R@186823|Alicyclobacillaceae	91061|Bacilli	S	Methylmuconolactone methyl-isomerase	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
GDHHQS2_k127_5803379_28	306281.AJLK01000103_gene3364	2.314e-151	484.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,1JJ7I@1189|Stigonemataceae	2|Bacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
GDHHQS2_k127_5803379_131	671143.DAMO_0021	1.124e-39	161.0	COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
GDHHQS2_k127_5803379_136	324602.Caur_3622	1.295e-36	149.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
GDHHQS2_k127_5803379_113	1122221.JHVI01000001_gene1797	7.559e-56	200.0	COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
GDHHQS2_k127_5803379_92	319795.Dgeo_1916	6.247e-76	263.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GDHHQS2_k127_5803379_150	926554.KI912664_gene1580	4.911e-30	125.0	COG3460@1|root,COG3460@2|Bacteria,1WIFI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	phenylacetic acid degradation	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
GDHHQS2_k127_5803379_27	1122223.KB890698_gene786	1.886e-159	507.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GDHHQS2_k127_5803379_64	1121090.KB894700_gene3295	6.529e-102	339.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GDHHQS2_k127_5803379_18	518766.Rmar_1548	3.027e-188	608.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD
GDHHQS2_k127_5803379_36	485918.Cpin_3443	2.115e-138	463.0	COG0161@1|root,COG0161@2|Bacteria,4PMIJ@976|Bacteroidetes,1J0MX@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
GDHHQS2_k127_5803379_189	326427.Cagg_3261	2.038e-06	59.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_179	326427.Cagg_3261	2.104e-11	75.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_181	326427.Cagg_3261	3.22e-09	68.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_32	926569.ANT_20700	1.383e-142	469.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GDHHQS2_k127_5803379_137	288705.RSal33209_3007	1.545e-36	147.0	COG3087@1|root,COG4478@1|root,COG3087@2|Bacteria,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,1W8XP@1268|Micrococcaceae	201174|Actinobacteria	D	TIGRFAM integral membrane protein TIGR01906	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
GDHHQS2_k127_5803379_178	552811.Dehly_1198	4.04e-12	71.0	2CEZQ@1|root,33C4G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_24	1120959.ATXF01000011_gene340	1.127e-162	529.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FKEP@85023|Microbacteriaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GDHHQS2_k127_5803379_31	316274.Haur_1660	6.754e-147	478.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi,3752N@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_5803379_19	926569.ANT_00880	2.281e-183	593.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS2_k127_5803379_117	390989.JOEG01000004_gene4106	1.874e-52	192.0	COG1859@1|root,COG1859@2|Bacteria,2HVJW@201174|Actinobacteria,4DDP2@85008|Micromonosporales	201174|Actinobacteria	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
GDHHQS2_k127_5803379_115	926569.ANT_07430	5.843e-55	206.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS2_k127_5803379_39	926569.ANT_23640	1.683e-131	440.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
GDHHQS2_k127_5803379_78	926550.CLDAP_26480	1.065e-90	310.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5803379_188	756499.Desde_1253	1.487e-06	57.0	2DN90@1|root,32W6G@2|Bacteria,1VC37@1239|Firmicutes,24KFW@186801|Clostridia,265FE@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_138	867845.KI911784_gene3554	2.184e-36	150.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS2_k127_5803379_26	926550.CLDAP_05420	2.802e-161	518.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_5803379_100	1122138.AQUZ01000019_gene8185	1.131e-68	242.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4DQUJ@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_5803379_11	324602.Caur_0954	4.029e-202	640.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_5803379_128	497964.CfE428DRAFT_3478	2.048e-45	173.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
GDHHQS2_k127_5803379_4	306281.AJLK01000030_gene1328	2.807e-238	747.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS2_k127_5803379_184	96561.Dole_0043	9.086e-07	63.0	COG5276@1|root,COG5276@2|Bacteria,1PE5R@1224|Proteobacteria,4375P@68525|delta/epsilon subdivisions,2X232@28221|Deltaproteobacteria,2MM6B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS2_k127_5803379_185	1150474.JQJI01000027_gene967	9.086e-07	63.0	COG1404@1|root,COG1404@2|Bacteria,2GCI9@200918|Thermotogae	200918|Thermotogae	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GDHHQS2_k127_5803379_166	1196323.ALKF01000164_gene338	8.441e-20	99.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,26UWQ@186822|Paenibacillaceae	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS2_k127_5803379_60	479434.Sthe_3089	7.273e-105	361.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27YU5@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS2_k127_5803379_161	479434.Sthe_3094	6.693e-25	111.0	COG4720@1|root,COG4720@2|Bacteria,2GA0R@200795|Chloroflexi,27YG3@189775|Thermomicrobia	189775|Thermomicrobia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF-ribofla_trS
GDHHQS2_k127_5803379_121	765420.OSCT_1844	2.351e-51	190.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
GDHHQS2_k127_5803379_63	926569.ANT_27130	9.655e-103	346.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GDHHQS2_k127_5803379_169	1235457.C404_23925	2.491e-19	99.0	2ECGA@1|root,336EK@2|Bacteria,1NG7Q@1224|Proteobacteria,2VXC5@28216|Betaproteobacteria,1KEYD@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_175	1173028.ANKO01000154_gene4735	3.752e-15	89.0	COG0457@1|root,COG0457@2|Bacteria	1173028.ANKO01000154_gene4735|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_70	472759.Nhal_2967	1.047e-97	331.0	COG0309@1|root,COG0309@2|Bacteria,1N04A@1224|Proteobacteria,1SK12@1236|Gammaproteobacteria,1X0HN@135613|Chromatiales	135613|Chromatiales	O	PFAM AIR synthase related protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_5803379_3	926550.CLDAP_17630	4.705e-242	760.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS2_k127_5803379_190	56110.Oscil6304_1478	7.276e-06	59.0	COG1413@1|root,COG1413@2|Bacteria,1GF6C@1117|Cyanobacteria,1HGH8@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_5803379_81	324602.Caur_3855	2.062e-85	301.0	COG0642@1|root,COG2205@2|Bacteria,2GBIC@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_5803379_90	1009370.ALO_12261	2.451e-77	265.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,4H3RA@909932|Negativicutes	909932|Negativicutes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_5803379_144	926569.ANT_28370	1.418e-33	139.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS2_k127_5803379_183	208444.JNYY01000025_gene5858	4.185e-07	61.0	2AZDP@1|root,31RMA@2|Bacteria,2GUFH@201174|Actinobacteria,4E3MZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
GDHHQS2_k127_5803379_7	926569.ANT_15470	1.111e-215	689.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi	200795|Chloroflexi	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS2_k127_5803379_42	309801.trd_1791	1.353e-126	416.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS2_k127_5803379_192	1337936.IJ00_05425	9.212e-05	50.0	2ETKQ@1|root,33M4D@2|Bacteria,1GB37@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_87	926569.ANT_08920	5.362e-79	275.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_5803379_109	926569.ANT_06180	8.809e-62	226.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_5803379_89	926569.ANT_10920	1.698e-77	268.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS2_k127_5803379_187	309801.trd_0475	1.283e-06	58.0	COG3103@1|root,COG4991@2|Bacteria,2G8N3@200795|Chloroflexi,27XRF@189775|Thermomicrobia	189775|Thermomicrobia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS2_k127_5803379_105	316274.Haur_0491	1.661e-64	236.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376A8@32061|Chloroflexia	2|Bacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3,4.2.3.3	ko:K01734,ko:K07315,ko:K10914	ko00640,ko01120,ko02020,ko02024,ko02025,ko02026,ko05111,map00640,map01120,map02020,map02024,map02025,map02026,map05111	-	R01016	RC00424	ko00000,ko00001,ko01000,ko03000,ko03021	-	-	-	CHASE2,HATPase_c_2,HTH_Crp_2,MGS,Response_reg,SpoIIE,cNMP_binding
GDHHQS2_k127_5803379_17	926569.ANT_25540	5.399e-189	607.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GDHHQS2_k127_5803379_164	926569.ANT_30930	1.357e-20	96.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
GDHHQS2_k127_5803379_67	926569.ANT_11320	5.951e-100	338.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_102	525904.Tter_1053	1.415e-65	230.0	COG0586@1|root,COG0586@2|Bacteria,2NPJ6@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS2_k127_5803379_127	309801.trd_0907	1.614e-46	183.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi,27Z2P@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS2_k127_5803379_132	926569.ANT_29880	7.366e-39	150.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS2_k127_5803379_14	926569.ANT_29890	1.437e-191	610.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS2_k127_5803379_20	926569.ANT_00970	6.571e-176	562.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
GDHHQS2_k127_5803379_172	760568.Desku_1683	9.478e-18	86.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,262GD@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS2_k127_5803379_9	926550.CLDAP_11170	9.83e-208	655.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS2_k127_5803379_48	215803.DB30_4900	3.062e-118	396.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_5803379_10	926569.ANT_01680	3.119e-202	642.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
GDHHQS2_k127_5803379_108	926569.ANT_01690	1.876e-63	224.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS2_k127_5803379_153	926569.ANT_30190	1.168e-28	120.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS2_k127_5803379_133	357808.RoseRS_3784	9.382e-38	153.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi,375SV@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
GDHHQS2_k127_5803379_94	357808.RoseRS_2409	3.058e-74	258.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
GDHHQS2_k127_5803379_59	717605.Theco_2496	4.804e-106	359.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,26QIQ@186822|Paenibacillaceae	91061|Bacilli	S	Hemolysins and related proteins containing CBS domains	corC3	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS2_k127_5803379_165	452863.Achl_1129	3.233e-20	99.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_119	309801.trd_1722	5.036e-52	188.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,27YAD@189775|Thermomicrobia	189775|Thermomicrobia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS2_k127_5803379_186	247490.KSU1_B0622	1.079e-06	59.0	COG0584@1|root,COG1413@1|root,COG0584@2|Bacteria,COG1413@2|Bacteria,2J0S0@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb,HEAT_2
GDHHQS2_k127_5803379_157	1358423.N180_18515	3.599e-27	121.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,1ITE5@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS2_k127_5803379_86	1117108.PAALTS15_23363	2.7e-79	272.0	COG2304@1|root,COG2304@2|Bacteria,1UXXE@1239|Firmicutes,4HAWY@91061|Bacilli,26TQ8@186822|Paenibacillaceae	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_5803379_163	1196323.ALKF01000201_gene2947	2.169e-22	110.0	COG0631@1|root,COG0631@2|Bacteria,1VW02@1239|Firmicutes,4HWA6@91061|Bacilli,26TND@186822|Paenibacillaceae	91061|Bacilli	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_103	1118054.CAGW01000018_gene4257	2.103e-65	238.0	COG0515@1|root,COG0515@2|Bacteria,1V1B6@1239|Firmicutes,4HFQF@91061|Bacilli,26RYX@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8,WG_beta_rep
GDHHQS2_k127_5803379_146	1042163.BRLA_c028330	5.839e-32	145.0	COG0631@1|root,COG0631@2|Bacteria,1VW02@1239|Firmicutes,4HWA6@91061|Bacilli,26TND@186822|Paenibacillaceae	91061|Bacilli	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_151	1442599.JAAN01000030_gene2059	1.139e-29	138.0	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1X54E@135614|Xanthomonadales	135614|Xanthomonadales	M	rhs family	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GDHHQS2_k127_5803379_104	743719.PaelaDRAFT_1451	2.895e-65	243.0	COG0515@1|root,COG0515@2|Bacteria,1V1B6@1239|Firmicutes,4HFQF@91061|Bacilli,26RYX@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8,WG_beta_rep
GDHHQS2_k127_5803379_125	1382356.JQMP01000003_gene2514	2.718e-49	186.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,27Y7W@189775|Thermomicrobia	189775|Thermomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS2_k127_5803379_2	56107.Cylst_0451	9.413e-284	898.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales	1117|Cyanobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
GDHHQS2_k127_5803379_116	926569.ANT_06850	1.08e-54	200.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GDHHQS2_k127_5803379_43	926569.ANT_06860	3.749e-125	414.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS2_k127_5803379_53	326427.Cagg_3847	1.847e-111	384.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi,374T2@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_5803379_57	324602.Caur_0531	7.063e-109	365.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi,375FD@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_5803379_8	1128421.JAGA01000002_gene342	8.807e-214	676.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS2_k127_5803379_47	765420.OSCT_1325	1.543e-119	393.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS2_k127_5803379_22	926569.ANT_12840	2.677e-164	576.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS2_k127_5803379_167	1128421.JAGA01000002_gene374	1.053e-19	102.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA
GDHHQS2_k127_5803379_93	926569.ANT_22560	2.771e-74	260.0	COG0524@1|root,COG0524@2|Bacteria,2G8C3@200795|Chloroflexi	200795|Chloroflexi	H	PFAM PfkB domain protein	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS2_k127_5803379_72	926569.ANT_22550	1.936e-96	324.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
GDHHQS2_k127_5803379_97	1122247.C731_4072	4.643e-73	258.0	COG1575@1|root,COG1575@2|Bacteria,2IPQ8@201174|Actinobacteria,23E29@1762|Mycobacteriaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GDHHQS2_k127_5803379_15	926569.ANT_16100	4.181e-190	606.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS2_k127_5803379_123	926550.CLDAP_16260	9.142e-50	186.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
GDHHQS2_k127_5803379_29	926550.CLDAP_00020	1.775e-149	480.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_5803379_98	485913.Krac_12126	3.504e-72	248.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi	200795|Chloroflexi	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS2_k127_5803379_25	338963.Pcar_0642	3.559e-162	523.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,43T9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Metallo-beta-lactamase superfamily domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GDHHQS2_k127_5803379_79	926569.ANT_02860	5.056e-88	304.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS2_k127_5803379_54	309807.SRU_2423	3.738e-111	377.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1FJQP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
GDHHQS2_k127_5803379_38	1249634.D781_0133	7.345e-132	430.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,3ZZM0@613|Serratia	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	wecB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297	Epimerase_2
GDHHQS2_k127_5803379_148	324602.Caur_1991	1.915e-30	126.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,375TA@32061|Chloroflexia	32061|Chloroflexia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GDHHQS2_k127_5803379_50	644966.Tmar_1299	7.201e-117	389.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS2_k127_5803379_176	926550.CLDAP_37450	7.135e-15	85.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_5803379_21	266117.Rxyl_0743	9.17e-168	535.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS2_k127_5803379_170	926569.ANT_22740	3.047e-19	92.0	COG0526@1|root,COG0526@2|Bacteria,2G7HX@200795|Chloroflexi	200795|Chloroflexi	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS2_k127_5803379_129	926550.CLDAP_00520	4.25e-43	167.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
GDHHQS2_k127_5803379_159	518766.Rmar_1679	4.216e-26	117.0	COG1977@1|root,COG1977@2|Bacteria,4NVU9@976|Bacteroidetes,1FJK9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS2_k127_5803379_145	598467.BrE312_2845	3.941e-33	132.0	COG1310@1|root,COG1310@2|Bacteria,1QRZQ@1224|Proteobacteria,1S558@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
GDHHQS2_k127_5803379_46	266117.Rxyl_0746	8.869e-120	393.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS2_k127_5803379_55	485913.Krac_5624	2.631e-110	365.0	COG0346@1|root,COG0346@2|Bacteria,2G7VB@200795|Chloroflexi	2|Bacteria	C	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS2_k127_5803379_44	926569.ANT_07740	3.926e-125	414.0	COG0577@1|root,COG0577@2|Bacteria,2G6MK@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS2_k127_5803379_76	926569.ANT_07730	6.4e-93	327.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
GDHHQS2_k127_5803379_83	926569.ANT_07720	1.13e-83	284.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_5803379_139	926569.ANT_04540	8.749e-36	139.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS2_k127_5803379_111	1304880.JAGB01000005_gene2461	8.363e-57	207.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia	186801|Clostridia	G	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS2_k127_5803379_91	926569.ANT_04560	2.882e-76	269.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
GDHHQS2_k127_5803379_80	926569.ANT_15670	1.368e-85	311.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_1	926569.ANT_03530	2.397e-312	979.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS2_k127_5803379_114	525904.Tter_1002	4.382e-55	201.0	COG1974@1|root,COG1974@2|Bacteria,2NPJG@2323|unclassified Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_5803379_65	391625.PPSIR1_21849	8.447e-102	347.0	COG0534@1|root,COG0534@2|Bacteria,1R3WH@1224|Proteobacteria,42Q54@68525|delta/epsilon subdivisions,2WM10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5803379_82	518766.Rmar_2420	7.031e-84	289.0	COG1218@1|root,COG1218@2|Bacteria,4PEDQ@976|Bacteroidetes,1FIY0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
GDHHQS2_k127_5803379_73	1254432.SCE1572_29530	2.312e-96	321.0	COG2746@1|root,COG2746@2|Bacteria,1MZ5F@1224|Proteobacteria,42N21@68525|delta/epsilon subdivisions,2X6R4@28221|Deltaproteobacteria,2Z3CF@29|Myxococcales	28221|Deltaproteobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
GDHHQS2_k127_5803379_141	326427.Cagg_3423	1.542e-34	139.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS2_k127_5803379_6	926569.ANT_30500	8.221e-217	715.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GDHHQS2_k127_5803379_56	926569.ANT_09430	4.374e-109	362.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS2_k127_5803379_62	926569.ANT_11680	7.939e-104	357.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
GDHHQS2_k127_5803379_99	1382356.JQMP01000003_gene1464	2.005e-70	271.0	COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS2_k127_5803379_134	479434.Sthe_1158	4.29e-37	163.0	COG3307@1|root,COG3307@2|Bacteria,2G79D@200795|Chloroflexi,27Y8C@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_5803379_110	1089553.Tph_c13460	1.896e-58	207.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,42GU1@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
GDHHQS2_k127_5803379_41	326427.Cagg_1192	1.168e-128	421.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2G5WJ@200795|Chloroflexi,375B3@32061|Chloroflexia	32061|Chloroflexia	H	PFAM magnesium chelatase ChlI subunit	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase,VWA_2
GDHHQS2_k127_5803379_58	926569.ANT_05390	3.851e-108	361.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS2_k127_5803379_130	926550.CLDAP_14930	1.383e-41	156.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS2_k127_5803379_107	1128421.JAGA01000002_gene1417	1.131e-63	224.0	COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria	2|Bacteria	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
GDHHQS2_k127_5803379_34	926569.ANT_02790	1.951e-140	473.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
GDHHQS2_k127_5803379_35	357808.RoseRS_3579	1.005e-139	451.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,374WM@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS2_k127_5803379_95	926550.CLDAP_33690	3.663e-74	268.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS2_k127_5803379_149	926569.ANT_11660	3.022e-30	126.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
GDHHQS2_k127_5803379_69	383372.Rcas_4271	3.751e-98	334.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_5803379_142	1379698.RBG1_1C00001G1815	2.858e-34	147.0	COG0477@1|root,COG2814@2|Bacteria,2NPJ1@2323|unclassified Bacteria	2|Bacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_5803379_61	926550.CLDAP_35100	4.532e-104	352.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS2_k127_5803379_40	926569.ANT_18360	8.984e-130	422.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS2_k127_5803379_52	926569.ANT_05010	1.653e-115	379.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS2_k127_5803379_16	1382306.JNIM01000001_gene2944	1.368e-189	597.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi	200795|Chloroflexi	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GDHHQS2_k127_5803379_23	309799.DICTH_0538	6.07e-164	524.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_5803379_75	926569.ANT_12150	1.68e-93	316.0	COG0834@1|root,COG0834@2|Bacteria,2G6HE@200795|Chloroflexi	200795|Chloroflexi	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GDHHQS2_k127_5803379_158	1307759.JOMJ01000003_gene652	4.452e-27	113.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,42VNQ@68525|delta/epsilon subdivisions,2WQ7J@28221|Deltaproteobacteria,2MC6I@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase, family 13	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
GDHHQS2_k127_5803379_5	669262.COK_0707	1.839e-226	733.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y7ZN@135625|Pasteurellales	135625|Pasteurellales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS2_k127_5803379_135	330214.NIDE3481	5.769e-37	141.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
GDHHQS2_k127_5803379_12	926550.CLDAP_33430	4.276e-202	632.0	COG4447@1|root,COG4447@2|Bacteria,2G5ZD@200795|Chloroflexi	200795|Chloroflexi	S	BNR/Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GDHHQS2_k127_5921628_25	525904.Tter_0463	4.13e-35	139.0	COG0071@1|root,COG0071@2|Bacteria,2NPXZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS2_k127_5921628_19	1128421.JAGA01000004_gene2493	1.34e-61	231.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	pepN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS2_k127_5921628_17	1382356.JQMP01000004_gene167	2.567e-72	264.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_5921628_16	926550.CLDAP_35810	2.782e-74	267.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GDHHQS2_k127_5921628_12	316274.Haur_3362	1.566e-108	360.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS2_k127_5921628_22	926569.ANT_18920	3.192e-55	207.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS2_k127_5921628_0	309801.trd_1549	9.842e-287	895.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS2_k127_5921628_23	926569.ANT_00590	2.475e-39	149.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS2_k127_5921628_36	243164.DET0751	2.736e-09	63.0	COG0291@1|root,COG0291@2|Bacteria,2G7D1@200795|Chloroflexi,34DG6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS2_k127_5921628_20	926569.ANT_02480	1.025e-60	214.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS2_k127_5921628_28	926550.CLDAP_35390	8.739e-32	127.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS2_k127_5921628_11	926569.ANT_25160	1.263e-120	402.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5921628_9	926569.ANT_25170	3.395e-127	425.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS2_k127_5921628_2	926550.CLDAP_35420	9.91e-184	584.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS2_k127_5921628_37	498848.TaqDRAFT_3909	1.234e-06	53.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS2_k127_5921628_3	868595.Desca_2486	9.929e-171	554.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS2_k127_5921628_10	926569.ANT_12010	5.625e-125	409.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS2_k127_5921628_14	357808.RoseRS_0616	4.051e-97	332.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS2_k127_5921628_8	404589.Anae109_4157	4.027e-128	430.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS2_k127_5921628_24	666686.B1NLA3E_16350	4.556e-36	142.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS2_k127_5921628_26	479434.Sthe_1868	5.958e-34	139.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi,27YEY@189775|Thermomicrobia	189775|Thermomicrobia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS2_k127_5921628_32	335541.Swol_1496	2.426e-21	94.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42K68@68298|Syntrophomonadaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS2_k127_5921628_30	926569.ANT_16040	1.048e-26	117.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS2_k127_5921628_5	926550.CLDAP_37840	5.191e-147	478.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS2_k127_5921628_6	1128421.JAGA01000002_gene834	3.014e-138	447.0	COG4608@1|root,COG4608@2|Bacteria,2NP9Y@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_5921628_7	926550.CLDAP_11120	5.279e-134	434.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_5921628_15	1232410.KI421418_gene2219	1.205e-75	265.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,43SA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS2_k127_5921628_18	1382356.JQMP01000003_gene2440	1.849e-64	233.0	COG0601@1|root,COG0601@2|Bacteria,2GA2P@200795|Chloroflexi,27YUQ@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_5921628_21	32049.SYNPCC7002_A0445	6.794e-59	226.0	COG0747@1|root,COG0747@2|Bacteria,1G0S3@1117|Cyanobacteria,1H02V@1129|Synechococcus	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS2_k127_5921628_4	243231.GSU1108	2.194e-170	547.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS2_k127_5921628_1	309801.trd_A0525	7.498e-245	791.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GDHHQS2_k127_5921628_38	1123270.ATUR01000002_gene2740	1.268e-06	55.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales	204457|Sphingomonadales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
GDHHQS2_k127_5921628_35	1120985.AUMI01000004_gene1319	2.293e-19	101.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4H2A6@909932|Negativicutes	909932|Negativicutes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS2_k127_5921628_29	1382306.JNIM01000001_gene2591	1.886e-28	124.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS2_k127_5921628_13	644966.Tmar_2037	4.288e-100	340.0	COG0446@1|root,COG0446@2|Bacteria,1UC47@1239|Firmicutes,24NN7@186801|Clostridia	186801|Clostridia	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_5921628_34	1128421.JAGA01000002_gene1543	1.689e-20	93.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GDHHQS2_k127_5921628_31	926690.KE386573_gene271	6.341e-26	124.0	arCOG01312@1|root,arCOG01312@2157|Archaea,2XVGY@28890|Euryarchaeota,23VD8@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
GDHHQS2_k127_5921628_27	926690.KE386573_gene2449	4.635e-33	140.0	COG0616@1|root,arCOG01311@2157|Archaea,2XUZ2@28890|Euryarchaeota,23V1R@183963|Halobacteria	183963|Halobacteria	O	COG0616 Periplasmic serine proteases (ClpP class)	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS2_k127_5976247_4	485913.Krac_5184	5.859e-50	186.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS2_k127_5976247_0	317619.ANKN01000202_gene1035	1.091e-253	798.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1MNE3@1212|Prochloraceae	1117|Cyanobacteria	IQ	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
GDHHQS2_k127_5976247_3	29306.JOBE01000013_gene6335	1.39e-60	218.0	28PCS@1|root,2ZC50@2|Bacteria,2GITP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5976247_1	926550.CLDAP_01280	3.281e-69	252.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_5976247_2	290315.Clim_1144	7.659e-69	236.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
GDHHQS2_k127_5976247_5	484022.Fphi_1829	2.069e-05	51.0	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,1T3G8@1236|Gammaproteobacteria,4619Z@72273|Thiotrichales	72273|Thiotrichales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS2_k127_6296215_6	1128421.JAGA01000003_gene3395	2.913e-118	392.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS2_k127_6296215_9	926569.ANT_06950	1.043e-97	327.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS2_k127_6296215_13	926569.ANT_06940	4.316e-84	288.0	COG0842@1|root,COG0842@2|Bacteria,2G8MV@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS2_k127_6296215_62	1173027.Mic7113_4389	4.08e-08	59.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_46	768671.ThimaDRAFT_3026	4.739e-29	120.0	COG1403@1|root,COG1403@2|Bacteria,1NI19@1224|Proteobacteria,1SIZN@1236|Gammaproteobacteria,1X1ZF@135613|Chromatiales	135613|Chromatiales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_33	76114.ebD26	3.722e-49	180.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_6296215_28	483219.LILAB_29540	1.956e-57	214.0	28M9U@1|root,2ZANN@2|Bacteria,1NXC3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_57	1122609.AUGT01000009_gene3057	2.181e-14	80.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS2_k127_6296215_3	316274.Haur_3911	3.282e-132	434.0	COG2059@1|root,COG2059@2|Bacteria,2G6NB@200795|Chloroflexi,375VI@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS2_k127_6296215_25	552811.Dehly_0442	9.986e-63	228.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
GDHHQS2_k127_6296215_22	671143.DAMO_0822	3.004e-70	257.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GDHHQS2_k127_6296215_55	909663.KI867150_gene2045	6.648e-17	85.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,2MQIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cytochrome b/b6/petB	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
GDHHQS2_k127_6296215_21	1379698.RBG1_1C00001G0780	1.819e-71	248.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
GDHHQS2_k127_6296215_51	290318.Cvib_1501	1.586e-20	98.0	COG0723@1|root,COG0723@2|Bacteria,1FE1T@1090|Chlorobi	1090|Chlorobi	C	PFAM Rieske 2Fe-2S domain protein	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
GDHHQS2_k127_6296215_15	926569.ANT_26980	1.248e-79	280.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
GDHHQS2_k127_6296215_11	926569.ANT_26970	2.479e-88	300.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
GDHHQS2_k127_6296215_53	926569.ANT_26960	6.569e-19	97.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_59	326427.Cagg_1239	2.657e-13	81.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_5	63737.Npun_F6039	7.84e-119	409.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc,TIR_2
GDHHQS2_k127_6296215_19	309801.trd_0062	2.221e-73	263.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,27XXN@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_6296215_17	926569.ANT_23380	1.858e-77	273.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS2_k127_6296215_1	1499967.BAYZ01000060_gene6002	1.111e-164	545.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
GDHHQS2_k127_6296215_44	1128427.KB904821_gene1548	1.525e-29	122.0	COG2402@1|root,COG2402@2|Bacteria,1G6UZ@1117|Cyanobacteria,1HCNZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_6296215_27	926550.CLDAP_23760	1.377e-57	213.0	COG2933@1|root,COG2933@2|Bacteria,2G6K6@200795|Chloroflexi	200795|Chloroflexi	J	FtsJ-like methyltransferase	-	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,THUMP
GDHHQS2_k127_6296215_7	926569.ANT_23400	2.602e-115	387.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS2_k127_6296215_70	1158182.KB905024_gene73	0.0004356	53.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX0E@135613|Chromatiales	135613|Chromatiales	U	PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
GDHHQS2_k127_6296215_2	497964.CfE428DRAFT_0631	1.376e-158	535.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
GDHHQS2_k127_6296215_56	1229172.JQFA01000002_gene3065	1.793e-16	90.0	COG0745@1|root,COG2972@1|root,COG0745@2|Bacteria,COG2972@2|Bacteria,1G4MZ@1117|Cyanobacteria,1HF29@1150|Oscillatoriales	1117|Cyanobacteria	KT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_12	926569.ANT_23420	1.025e-85	295.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS2_k127_6296215_49	927677.ALVU02000001_gene4090	4.456e-26	112.0	COG4113@1|root,COG4113@2|Bacteria,1G6BG@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS2_k127_6296215_68	246969.TAM4_2401	0.0002036	47.0	COG2880@1|root,arCOG03880@2157|Archaea	2157|Archaea	S	Possibly the antitoxin component of a type II toxin- antitoxin (TA) system	-	-	-	-	-	-	-	-	-	-	-	-	DUF104
GDHHQS2_k127_6296215_60	756067.MicvaDRAFT_1374	4.237e-13	81.0	COG1017@1|root,COG1357@1|root,COG1017@2|Bacteria,COG1357@2|Bacteria,1G3MG@1117|Cyanobacteria,1H9R2@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	Globin,Pentapeptide
GDHHQS2_k127_6296215_8	765420.OSCT_1132	1.268e-109	362.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS2_k127_6296215_47	1173024.KI912151_gene1924	2.653e-28	118.0	COG0789@1|root,COG0789@2|Bacteria,1GE37@1117|Cyanobacteria,1JM9Z@1189|Stigonemataceae	1117|Cyanobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS2_k127_6296215_0	1089550.ATTH01000001_gene1294	2.117e-201	642.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes	976|Bacteroidetes	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
GDHHQS2_k127_6296215_58	1869.MB27_12150	2.585e-14	85.0	COG5542@1|root,COG5542@2|Bacteria,2HWIG@201174|Actinobacteria,4DIWB@85008|Micromonosporales	201174|Actinobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
GDHHQS2_k127_6296215_29	485913.Krac_0877	2.576e-56	201.0	2BWWR@1|root,2ZG0F@2|Bacteria	2|Bacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_6296215_66	234267.Acid_7571	0.0001588	54.0	COG0823@1|root,COG0823@2|Bacteria,3Y95P@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_6296215_10	926569.ANT_31560	1.086e-95	327.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GDHHQS2_k127_6296215_63	357808.RoseRS_2434	1.142e-07	63.0	COG1716@1|root,COG1716@2|Bacteria,2G8U3@200795|Chloroflexi,375MN@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA
GDHHQS2_k127_6296215_30	485913.Krac_3704	2.678e-53	204.0	COG0477@1|root,COG2814@2|Bacteria,2G77Q@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6296215_42	203119.Cthe_2576	6.251e-33	143.0	2EEBD@1|root,3385Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_26	926569.ANT_10690	4.025e-60	215.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS2_k127_6296215_38	1242864.D187_003185	2.084e-42	169.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GDHHQS2_k127_6296215_35	272844.PAB0474	8.133e-45	176.0	COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,243FM@183968|Thermococci	183968|Thermococci	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS2_k127_6296215_41	926569.ANT_04910	2.225e-35	139.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS2_k127_6296215_48	102232.GLO73106DRAFT_00023200	3.573e-26	112.0	COG2361@1|root,COG2361@2|Bacteria,1G7TP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS2_k127_6296215_43	1173027.Mic7113_2124	7.633e-31	124.0	COG1669@1|root,COG1669@2|Bacteria,1G7TF@1117|Cyanobacteria,1HCFB@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS2_k127_6296215_24	926569.ANT_09630	3.976e-65	235.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS2_k127_6296215_61	316274.Haur_2376	4.863e-13	74.0	2EM6G@1|root,33EVQ@2|Bacteria,2G9RV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6296215_36	1094980.Mpsy_0054	1.138e-44	188.0	COG0642@1|root,COG2203@1|root,arCOG02348@1|root,arCOG02348@2157|Archaea,arCOG02356@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota	28890|Euryarchaeota	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3
GDHHQS2_k127_6296215_50	525904.Tter_0136	3.462e-24	117.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_6296215_65	996637.SGM_3597	1.705e-05	56.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GDHHQS2_k127_6296215_18	485913.Krac_3228	1.758e-75	261.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi	200795|Chloroflexi	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS2_k127_6296215_4	485913.Krac_3229	1.244e-122	400.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_6296215_39	1068980.ARVW01000001_gene7088	2.352e-37	144.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4E3I0@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GDHHQS2_k127_6296215_16	1144275.COCOR_04108	7.048e-79	272.0	COG2085@1|root,COG2085@2|Bacteria,1NF95@1224|Proteobacteria,4380B@68525|delta/epsilon subdivisions,2X3AC@28221|Deltaproteobacteria,2YURK@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS2_k127_6296215_14	42256.RradSPS_2536	6.777e-84	289.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_6296215_20	1040987.AZUY01000013_gene2836	4.346e-72	253.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2VEWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS2_k127_6296215_32	316274.Haur_0363	9.68e-51	190.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,3776W@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS2_k127_6296215_37	1169161.KB897731_gene189	3.931e-44	164.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
GDHHQS2_k127_6296215_34	446470.Snas_3571	8.863e-49	181.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria	201174|Actinobacteria	H	Bifunctional deaminase-reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_6296215_23	479434.Sthe_2017	4.289e-69	244.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi,27Y0J@189775|Thermomicrobia	189775|Thermomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS2_k127_6296215_40	1385517.N800_06875	6.217e-37	148.0	COG1028@1|root,COG1028@2|Bacteria,1RI09@1224|Proteobacteria,1S78S@1236|Gammaproteobacteria,1X5ZY@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS2_k127_6296215_31	383372.Rcas_0525	4.85e-51	188.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_6358872_17	926569.ANT_29620	1.099e-116	396.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GDHHQS2_k127_6358872_68	926550.CLDAP_35480	4.522e-20	106.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
GDHHQS2_k127_6358872_45	926550.CLDAP_35470	6.673e-49	201.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
GDHHQS2_k127_6358872_38	926550.CLDAP_35470	6.187e-68	248.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
GDHHQS2_k127_6358872_32	926550.CLDAP_35490	2.988e-81	285.0	COG2730@1|root,COG3103@1|root,COG2730@2|Bacteria,COG4991@2|Bacteria,2G7Y2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS2_k127_6358872_71	1304888.ATWF01000001_gene1188	7.118e-18	89.0	COG0642@1|root,COG2199@1|root,COG0642@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	M1-573	-	2.7.13.3	ko:K11527,ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg
GDHHQS2_k127_6358872_73	402880.MmarC5_1651	1.387e-17	92.0	arCOG02879@1|root,arCOG02879@2157|Archaea,2XYKT@28890|Euryarchaeota,23R3A@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
GDHHQS2_k127_6358872_36	479434.Sthe_0945	4.583e-71	247.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GDHHQS2_k127_6358872_63	926550.CLDAP_17890	2.371e-27	115.0	COG0718@1|root,COG0718@2|Bacteria,2G77S@200795|Chloroflexi	200795|Chloroflexi	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS2_k127_6358872_13	926569.ANT_01340	4.64e-126	424.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS2_k127_6358872_41	926550.CLDAP_11890	6.673e-51	194.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
GDHHQS2_k127_6358872_31	926569.ANT_11910	7.06e-82	278.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_6358872_8	926569.ANT_28910	4.044e-154	498.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS2_k127_6358872_16	926569.ANT_18180	9.665e-117	388.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS2_k127_6358872_33	926569.ANT_18190	1.549e-72	259.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS2_k127_6358872_30	309801.trd_0216	2.343e-86	301.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS2_k127_6358872_43	1144275.COCOR_05764	4.167e-50	198.0	COG0642@1|root,COG2205@2|Bacteria	1144275.COCOR_05764|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6358872_2	479434.Sthe_2647	3.228e-224	709.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,27XX7@189775|Thermomicrobia	189775|Thermomicrobia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
GDHHQS2_k127_6358872_34	926569.ANT_03510	6.919e-72	246.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS2_k127_6358872_18	926569.ANT_03500	2.63e-104	343.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS2_k127_6358872_46	926569.ANT_03490	8.797e-47	179.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS2_k127_6358872_10	926550.CLDAP_16500	1.53e-143	463.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
GDHHQS2_k127_6358872_22	1125863.JAFN01000001_gene2311	3.616e-97	331.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS2_k127_6358872_55	1455608.JDTH01000002_gene1395	3.941e-33	132.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_6358872_0	926569.ANT_04530	0.0	1077.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
GDHHQS2_k127_6358872_20	926550.CLDAP_07480	2.207e-102	346.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS2_k127_6358872_15	661478.OP10G_0721	5.519e-119	391.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS2_k127_6358872_3	926569.ANT_30000	2.219e-205	665.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
GDHHQS2_k127_6358872_23	383372.Rcas_3406	1.744e-96	324.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS2_k127_6358872_42	1163671.JAGI01000002_gene2359	2.103e-50	188.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,36I75@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS2_k127_6358872_67	926569.ANT_01150	2.97e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS2_k127_6358872_64	649747.HMPREF0083_03418	1.259e-26	121.0	COG0500@1|root,COG2226@2|Bacteria,1UHIX@1239|Firmicutes,4HFT8@91061|Bacilli,2723N@186822|Paenibacillaceae	91061|Bacilli	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS2_k127_6358872_26	1370121.AUWS01000025_gene3062	2.702e-91	312.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,234Z2@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS2_k127_6358872_7	926550.CLDAP_17140	6.655e-156	505.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS2_k127_6358872_6	479434.Sthe_1273	3.692e-158	512.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GDHHQS2_k127_6358872_44	867845.KI911784_gene3227	4.807e-49	189.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi,376K8@32061|Chloroflexia	32061|Chloroflexia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS2_k127_6358872_12	321327.CYA_2481	9.147e-140	461.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
GDHHQS2_k127_6358872_48	926550.CLDAP_31770	1.373e-39	168.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6358872_78	926560.KE387027_gene896	2.971e-08	64.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
GDHHQS2_k127_6358872_72	110663.KI911558_gene2449	9.972e-18	87.0	COG0851@1|root,COG0851@2|Bacteria,1G7SM@1117|Cyanobacteria,1H14A@1129|Synechococcus	1117|Cyanobacteria	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
GDHHQS2_k127_6358872_21	316274.Haur_3422	1.693e-98	332.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi,375DJ@32061|Chloroflexia	32061|Chloroflexia	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
GDHHQS2_k127_6358872_47	926569.ANT_09730	4.057e-46	177.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
GDHHQS2_k127_6358872_84	994573.T472_0212765	0.0006191	46.0	COG2452@1|root,COG2452@2|Bacteria,1VBG0@1239|Firmicutes,25H1U@186801|Clostridia,36V7B@31979|Clostridiaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS2_k127_6358872_11	1230343.CANP01000046_gene3647	1.552e-141	462.0	COG0827@1|root,COG0827@2|Bacteria,1QYXX@1224|Proteobacteria,1SKI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6358872_51	661478.OP10G_0619	4.048e-37	158.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
GDHHQS2_k127_6358872_4	926569.ANT_19070	2.255e-202	644.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GDHHQS2_k127_6358872_24	926550.CLDAP_16140	1.082e-92	315.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
GDHHQS2_k127_6358872_77	272134.KB731324_gene2288	3.469e-09	67.0	COG1357@1|root,COG1357@2|Bacteria,1G3EU@1117|Cyanobacteria,1H7ZI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS2_k127_6358872_82	926550.CLDAP_17520	0.0001354	55.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6358872_49	1192034.CAP_8990	2.587e-38	162.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6358872_58	1131462.DCF50_p2505	1.7e-32	130.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,262AG@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
GDHHQS2_k127_6358872_75	926550.CLDAP_09780	1.942e-13	82.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS2_k127_6358872_61	926550.CLDAP_31420	2.727e-28	126.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6358872_62	926569.ANT_06730	2.316e-27	115.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6358872_50	1121405.dsmv_1643	1.453e-37	146.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,42TWN@68525|delta/epsilon subdivisions,2WQDD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS2_k127_6358872_40	357808.RoseRS_2507	1.197e-58	226.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6358872_70	1121472.AQWN01000010_gene597	1.514e-19	96.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,2616F@186807|Peptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
GDHHQS2_k127_6358872_14	255470.cbdbA861	3.578e-119	393.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,34CT4@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS2_k127_6358872_39	926550.CLDAP_21020	1.612e-64	227.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_6358872_56	926550.CLDAP_21020	5.247e-33	132.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_6358872_54	1120973.AQXL01000121_gene96	2.936e-33	134.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,27ANI@186823|Alicyclobacillaceae	91061|Bacilli	CO	Glutathione peroxidase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS2_k127_6358872_1	926569.ANT_11950	1.565e-226	717.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS2_k127_6358872_19	1128421.JAGA01000002_gene1657	1.395e-102	343.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	lspL	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_6358872_27	340099.Teth39_0506	1.031e-90	308.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,42EK9@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6358872_52	926569.ANT_18660	9.983e-36	145.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
GDHHQS2_k127_6358872_57	1499967.BAYZ01000095_gene4168	1.7e-32	147.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
GDHHQS2_k127_6358872_69	358823.DF19_39535	7.622e-20	106.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
GDHHQS2_k127_6358872_80	398512.JQKC01000005_gene5338	2.937e-06	57.0	2DBSS@1|root,2ZATI@2|Bacteria,1V481@1239|Firmicutes,24C13@186801|Clostridia,3WICM@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
GDHHQS2_k127_6358872_66	1348663.KCH_61880	5.013e-26	116.0	COG3485@1|root,COG3979@1|root,COG3485@2|Bacteria,COG3979@2|Bacteria,2GNNC@201174|Actinobacteria,2M3ZI@2063|Kitasatospora	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
GDHHQS2_k127_6358872_29	926550.CLDAP_05930	1.199e-88	299.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
GDHHQS2_k127_6358872_35	671143.DAMO_1601	1.64e-71	251.0	COG1526@1|root,COG1526@2|Bacteria,2NPF9@2323|unclassified Bacteria	2|Bacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,NTP_transf_3
GDHHQS2_k127_6358872_76	1197706.AKKK01000043_gene1750	2.817e-11	70.0	2ECTF@1|root,336QZ@2|Bacteria,2GR5H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6358872_5	926550.CLDAP_05920	3.719e-202	644.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS2_k127_6358872_28	926550.CLDAP_29920	3.834e-89	308.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GDHHQS2_k127_6358872_25	926550.CLDAP_29930	1.077e-91	315.0	COG0438@1|root,COG0438@2|Bacteria,2G82Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6358872_83	1150864.MILUP08_41475	0.0001451	55.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,PKD,ThuA
GDHHQS2_k127_6358872_60	67275.JOAP01000013_gene5013	7.437e-31	132.0	COG2746@1|root,COG2746@2|Bacteria,2IC5T@201174|Actinobacteria	201174|Actinobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
GDHHQS2_k127_6358872_79	1046627.BZARG_988	8.271e-08	63.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_6358872_37	1038862.KB893806_gene3303	6.352e-69	243.0	COG1215@1|root,COG1215@2|Bacteria,1R26S@1224|Proteobacteria,2TZBX@28211|Alphaproteobacteria,3K3FB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_6358872_53	1340493.JNIF01000003_gene4581	1.731e-33	139.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
GDHHQS2_k127_6358872_65	1499967.BAYZ01000014_gene6405	3.097e-26	118.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
GDHHQS2_k127_6358872_9	1499967.BAYZ01000026_gene1631	1.43e-151	500.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_6358872_74	1476876.JOJO01000054_gene8268	7.538e-16	78.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
GDHHQS2_k127_6439809_16	326427.Cagg_2576	1.084e-106	350.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi,377C5@32061|Chloroflexia	32061|Chloroflexia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
GDHHQS2_k127_6439809_10	324602.Caur_1927	2.07e-131	428.0	COG2197@1|root,COG2197@2|Bacteria,2G7VT@200795|Chloroflexi,376CA@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS2_k127_6439809_6	324602.Caur_1928	1.299e-166	539.0	COG1129@1|root,COG4585@1|root,COG1129@2|Bacteria,COG4585@2|Bacteria,2G8A4@200795|Chloroflexi,3771D@32061|Chloroflexia	32061|Chloroflexia	GT	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,HisKA_3
GDHHQS2_k127_6439809_2	485913.Krac_0085	1.985e-206	655.0	COG2189@1|root,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
GDHHQS2_k127_6439809_34	56107.Cylst_2729	1.446e-35	140.0	COG2852@1|root,COG2852@2|Bacteria,1GNS3@1117|Cyanobacteria,1HP42@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS2_k127_6439809_15	926569.ANT_29930	1.764e-114	378.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
GDHHQS2_k127_6439809_52	880072.Desac_1083	2.004e-13	79.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS2_k127_6439809_36	1122223.KB890700_gene1916	2.188e-33	134.0	COG0517@1|root,COG0517@2|Bacteria,1WI6I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_6439809_39	926550.CLDAP_28530	2.652e-32	132.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS2_k127_6439809_8	357808.RoseRS_0911	1.195e-159	514.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi,376DI@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GDHHQS2_k127_6439809_54	103733.JNYO01000032_gene1187	1.952e-12	71.0	COG0724@1|root,COG0724@2|Bacteria,2H1J0@201174|Actinobacteria	201174|Actinobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS2_k127_6439809_57	13333.ERN11388	3.237e-08	58.0	KOG4207@1|root,KOG4207@2759|Eukaryota,37SMK@33090|Viridiplantae,3G8DC@35493|Streptophyta	35493|Streptophyta	A	serine arginine-rich splicing factor	-	GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0031974,GO:0031981,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K12891	ko03040,ko05168,map03040,map05168	-	-	-	ko00000,ko00001,ko03041	-	-	-	RRM_1
GDHHQS2_k127_6439809_43	1370125.AUWT01000041_gene287	6.736e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,23AKA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_6439809_44	1123023.JIAI01000001_gene7136	1.446e-23	105.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4EDXA@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_6439809_42	926550.CLDAP_32530	2.174e-27	117.0	COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_6439809_38	926560.KE387023_gene2407	1.057e-32	134.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS2_k127_6439809_67	82995.CR62_11935	0.0005638	48.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,402G0@613|Serratia	1236|Gammaproteobacteria	CH	Protoporphyrinogen oxidase	hemG	GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3850,iAPECO1_1312.APECO1_2607,iB21_1397.B21_03690,iBWG_1329.BWG_3526,iE2348C_1286.E2348C_4162,iECABU_c1320.ECABU_c43520,iECBD_1354.ECBD_4175,iECB_1328.ECB_03741,iECDH10B_1368.ECDH10B_4039,iECDH1ME8569_1439.ECDH1ME8569_3727,iECD_1391.ECD_03741,iECED1_1282.ECED1_4552,iECH74115_1262.ECH74115_5289,iECIAI1_1343.ECIAI1_4043,iECNA114_1301.ECNA114_4159,iECOK1_1307.ECOK1_4319,iECS88_1305.ECS88_4298,iECSF_1327.ECSF_3707,iECSP_1301.ECSP_4903,iECs_1301.ECs4778,iEcDH1_1363.EcDH1_4131,iEcHS_1320.EcHS_A4073,iEcolC_1368.EcolC_4160,iG2583_1286.G2583_4648,iJO1366.b3850,iJR904.b3850,iLF82_1304.LF82_0981,iNRG857_1313.NRG857_19220,iSDY_1059.SDY_3895,iUMN146_1321.UM146_19505,iUMNK88_1353.UMNK88_4678,iUTI89_1310.UTI89_C4435,iY75_1357.Y75_RS17835,iZ_1308.Z5372,ic_1306.c4797	Flavodoxin_5
GDHHQS2_k127_6439809_5	1242864.D187_001830	2.821e-177	596.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
GDHHQS2_k127_6439809_12	1242864.D187_007864	3.376e-123	406.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
GDHHQS2_k127_6439809_23	1410668.JNKC01000001_gene1810	2.061e-84	289.0	COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,24JHQ@186801|Clostridia,36M0P@31979|Clostridiaceae	186801|Clostridia	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_6439809_11	886293.Sinac_0410	1.245e-130	453.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
GDHHQS2_k127_6439809_65	1227349.C170_18647	3.563e-05	57.0	COG2304@1|root,COG2304@2|Bacteria,1UYIW@1239|Firmicutes,4HRS3@91061|Bacilli,26SAJ@186822|Paenibacillaceae	91061|Bacilli	S	Von Willebrand factor	vWFA1	-	-	-	-	-	-	-	-	-	-	-	VWA
GDHHQS2_k127_6439809_9	269799.Gmet_2497	3.493e-154	502.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS2_k127_6439809_26	926569.ANT_05940	9.786e-76	261.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi	200795|Chloroflexi	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS2_k127_6439809_3	926569.ANT_21150	7.98e-195	614.0	COG0738@1|root,COG0738@2|Bacteria,2G70U@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6439809_4	316274.Haur_1949	1.057e-188	602.0	COG1680@1|root,COG1680@2|Bacteria,2G7QB@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS2_k127_6439809_58	72019.SARC_05121T0	3.473e-08	65.0	COG2335@1|root,KOG1437@2759|Eukaryota	2759|Eukaryota	M	regulation of chemokine (C-C motif) ligand 2 secretion	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin
GDHHQS2_k127_6439809_35	234267.Acid_0752	8.505e-34	135.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS2_k127_6439809_62	171693.BN988_00023	4.772e-06	53.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,23KVT@182709|Oceanobacillus	91061|Bacilli	S	YtxH-like protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS2_k127_6439809_41	1128421.JAGA01000002_gene949	1.119e-27	113.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_6439809_61	765420.OSCT_2727	3.64e-06	58.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS2_k127_6439809_29	296591.Bpro_1275	9.152e-56	199.0	COG4274@1|root,COG4274@2|Bacteria,1RKGA@1224|Proteobacteria	1224|Proteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
GDHHQS2_k127_6439809_18	926569.ANT_27540	1.999e-94	321.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS2_k127_6439809_31	886293.Sinac_2076	8.561e-48	177.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GDHHQS2_k127_6439809_24	497964.CfE428DRAFT_3859	7.999e-78	271.0	COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_6439809_68	398511.BpOF4_02310	0.0007487	45.0	2EFZF@1|root,339RM@2|Bacteria,1VMG6@1239|Firmicutes,4HR8G@91061|Bacilli,1ZK3J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6439809_37	1279009.ADICEAN_02929	3.777e-33	136.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS2_k127_6439809_49	485913.Krac_4543	1.69e-17	87.0	2E4XU@1|root,32ZRS@2|Bacteria,2G9RW@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6439809_47	572480.Arnit_2000	6.259e-19	88.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,42X0E@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM Transglycosylase-associated protein	MA20_01300	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_6439809_33	1469607.KK073768_gene435	5.703e-39	152.0	COG2852@1|root,COG2852@2|Bacteria,1GNS3@1117|Cyanobacteria,1HP42@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS2_k127_6439809_63	1206720.BAFQ01000174_gene4527	7.489e-06	54.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4G93Y@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_6439809_13	926569.ANT_09870	4.5e-120	410.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GDHHQS2_k127_6439809_32	521674.Plim_1443	5.895e-42	160.0	COG4762@1|root,COG4762@2|Bacteria,2IZUS@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
GDHHQS2_k127_6439809_50	13035.Dacsa_2404	3.71e-17	83.0	COG2026@1|root,COG2026@2|Bacteria,1GA93@1117|Cyanobacteria	1117|Cyanobacteria	DJ	TIGRFAM addiction module toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS2_k127_6439809_66	13035.Dacsa_2405	0.0004873	46.0	2EHUB@1|root,33BJZ@2|Bacteria,1GAFK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6439809_53	926569.ANT_31720	5.222e-13	69.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS2_k127_6439809_1	926569.ANT_31720	4.491e-274	852.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS2_k127_6439809_40	1111134.HMPREF1253_0456	2.219e-28	126.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,22GIG@1570339|Peptoniphilaceae	186801|Clostridia	E	ABC transporter, substrate-binding protein, family 5	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS2_k127_6439809_21	1380347.JNII01000007_gene178	4.101e-85	308.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS2_k127_6439809_25	552811.Dehly_1421	4.617e-77	276.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi,34CWT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
GDHHQS2_k127_6439809_56	926569.ANT_18580	1.46e-09	68.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GDHHQS2_k127_6439809_45	398512.JQKC01000001_gene2373	3.454e-20	100.0	COG2199@1|root,COG3706@2|Bacteria,1TSTT@1239|Firmicutes,24CR8@186801|Clostridia,3WHFR@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,RHH_3
GDHHQS2_k127_6439809_30	345341.KUTG_09855	1.191e-52	194.0	2C73B@1|root,330Z7@2|Bacteria,2IIMQ@201174|Actinobacteria,4E6EA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS2_k127_6439809_14	886293.Sinac_4911	2.862e-115	385.0	COG2124@1|root,COG2124@2|Bacteria,2IZTH@203682|Planctomycetes	203682|Planctomycetes	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS2_k127_6439809_59	765913.ThidrDRAFT_3584	1.096e-07	60.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,1SHX0@1236|Gammaproteobacteria,1WZKQ@135613|Chromatiales	135613|Chromatiales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GDHHQS2_k127_6439809_0	926569.ANT_31250	6.719e-305	962.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS2_k127_6439809_27	765420.OSCT_2848	6.035e-71	257.0	COG1994@1|root,COG1994@2|Bacteria,2G8E2@200795|Chloroflexi,3777K@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS2_k127_6439809_19	926550.CLDAP_16330	8.359e-87	315.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS2_k127_6439809_48	1206733.BAGC01000002_gene5417	5.966e-18	96.0	COG3858@1|root,COG3858@2|Bacteria,2GM95@201174|Actinobacteria,4G080@85025|Nocardiaceae	201174|Actinobacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
GDHHQS2_k127_6439809_46	589924.Ferp_0472	2.405e-19	92.0	COG3042@1|root,arCOG12676@2157|Archaea,2Y52K@28890|Euryarchaeota,247DJ@183980|Archaeoglobi	183980|Archaeoglobi	S	Domain of unknown function (DUF333)	-	-	-	ko:K09712	-	-	-	-	ko00000	-	-	-	DUF333
GDHHQS2_k127_6439809_7	1449126.JQKL01000043_gene1900	2.37e-160	527.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
GDHHQS2_k127_6439809_60	324602.Caur_1173	2.257e-07	61.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS2_k127_6439809_51	1089552.KI911559_gene2455	2.039e-16	89.0	COG1266@1|root,COG1266@2|Bacteria,1NF98@1224|Proteobacteria,2UHG6@28211|Alphaproteobacteria,2JUK0@204441|Rhodospirillales	204441|Rhodospirillales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_6439809_22	1173023.KE650772_gene5625	4.508e-85	302.0	2EW81@1|root,33PKX@2|Bacteria,1GBWY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6439809_20	1120971.AUCA01000049_gene794	2.983e-85	297.0	COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli	91061|Bacilli	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
GDHHQS2_k127_6439809_28	326427.Cagg_3772	2.647e-61	236.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_6447695_28	697281.Mahau_2460	1.132e-32	137.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia,42INN@68295|Thermoanaerobacterales	186801|Clostridia	S	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS2_k127_6447695_34	768710.DesyoDRAFT_1912	5.936e-23	111.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS2_k127_6447695_31	926569.ANT_03880	1.415e-28	122.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GDHHQS2_k127_6447695_38	926550.CLDAP_10940	3.233e-18	100.0	COG1807@1|root,COG4745@1|root,COG1807@2|Bacteria,COG4745@2|Bacteria,2G9MT@200795|Chloroflexi	200795|Chloroflexi	O	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_13	864069.MicloDRAFT_00025890	4.918e-70	249.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,2TSCT@28211|Alphaproteobacteria,1JUA4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_6447695_43	1380347.JNII01000007_gene386	3.958e-13	80.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ERZZ@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
GDHHQS2_k127_6447695_19	357808.RoseRS_4265	2.18e-50	190.0	COG1216@1|root,COG1216@2|Bacteria,2G7UG@200795|Chloroflexi,3764Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GDHHQS2_k127_6447695_20	558152.IQ37_04455	2.582e-50	190.0	2DB8K@1|root,2Z7S1@2|Bacteria,4NI7A@976|Bacteroidetes,1I0N2@117743|Flavobacteriia,3ZRFB@59732|Chryseobacterium	976|Bacteroidetes	I	Streptomycin adenylyltransferase	aadK	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
GDHHQS2_k127_6447695_16	326427.Cagg_0115	3.327e-56	221.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6447695_47	222534.KB893705_gene5914	1.591e-05	47.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
GDHHQS2_k127_6447695_24	748247.AZKH_2096	5.987e-42	170.0	COG0642@1|root,COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg
GDHHQS2_k127_6447695_14	383372.Rcas_4163	1.039e-69	244.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS2_k127_6447695_32	1110502.TMO_2806	2.058e-26	121.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria	1224|Proteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS2_k127_6447695_48	383372.Rcas_2764	4.024e-05	51.0	2EV6B@1|root,33NM4@2|Bacteria,2G7I5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_30	1035191.HMPREF0185_01407	5.001e-29	124.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2KGBQ@204458|Caulobacterales	204458|Caulobacterales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS2_k127_6447695_5	1125863.JAFN01000001_gene2600	8.044e-108	366.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria	1224|Proteobacteria	C	PFAM FAD linked oxidase domain protein	dld	GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15	ko:K00004,ko:K00102,ko:K00104	ko00620,ko00630,ko00650,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map00650,map01100,map01110,map01120,map01130	-	R00197,R00475,R02855,R02946,R10504	RC00042,RC00044,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS2_k127_6447695_45	555779.Dthio_PD1275	1.128e-12	70.0	2E4DR@1|root,32Z92@2|Bacteria,1NI8U@1224|Proteobacteria,42XK2@68525|delta/epsilon subdivisions,2WT6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_46	211165.AJLN01000110_gene66	1.858e-09	61.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_50	317936.Nos7107_0699	0.0001028	47.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7YD@1117|Cyanobacteria,1HP9N@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_26	926569.ANT_23520	3.565e-40	160.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS2_k127_6447695_41	290315.Clim_1904	1.036e-14	75.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_6447695_42	1163617.SCD_n01662	1.612e-13	73.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria	1224|Proteobacteria	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_6447695_22	926569.ANT_23560	4.668e-48	178.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GDHHQS2_k127_6447695_18	883078.HMPREF9695_00110	1.939e-54	200.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,3K6HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_6447695_1	926569.ANT_30500	1.976e-172	576.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GDHHQS2_k127_6447695_37	357808.RoseRS_1412	1.331e-18	93.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6447695_29	316274.Haur_3010	8.017e-31	140.0	arCOG10517@1|root,31Y5Z@2|Bacteria,2G8TN@200795|Chloroflexi	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_35	1239962.C943_03877	2.86e-22	113.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
GDHHQS2_k127_6447695_21	326427.Cagg_3759	4.476e-48	178.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS2_k127_6447695_39	326427.Cagg_3758	5.237e-18	96.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6447695_10	926550.CLDAP_01570	2.063e-78	270.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_6447695_44	309801.trd_0602	5.964e-13	75.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
GDHHQS2_k127_6447695_12	357808.RoseRS_2229	1.847e-72	270.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_6447695_51	1238425.J07HQW2_01626	0.0001959	47.0	arCOG09407@1|root,arCOG09407@2157|Archaea,2Y0FF@28890|Euryarchaeota,23XN6@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_6447695_52	760192.Halhy_1557	0.0004809	47.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GDHHQS2_k127_6447695_3	66897.DJ64_06265	3.563e-132	434.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
GDHHQS2_k127_6447695_8	316067.Geob_1481	8.634e-80	273.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,43UY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
GDHHQS2_k127_6447695_11	485913.Krac_9544	7.668e-78	266.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_6447695_17	1323361.JPOC01000072_gene3090	1.574e-55	198.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4G18G@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GDHHQS2_k127_6447695_33	215803.DB30_5964	1.06e-25	115.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,DUF1905,OmdA
GDHHQS2_k127_6447695_23	1229780.BN381_100082	1.177e-42	171.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,NB-ARC,Pentapeptide,WD40
GDHHQS2_k127_6447695_9	1094980.Mpsy_1961	3.464e-79	269.0	COG0262@1|root,arCOG01490@2157|Archaea,2XYCD@28890|Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_6447695_0	926550.CLDAP_05820	4.249e-219	702.0	COG1397@1|root,COG1397@2|Bacteria,2G5WN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS2_k127_6447695_36	42256.RradSPS_2282	1.831e-20	98.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6447695_25	313606.M23134_06393	9.195e-41	154.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_6447695_40	661478.OP10G_0519	8.279e-16	88.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.1.1.72,2.7.1.15,2.7.1.4	ko:K00571,ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000,ko02048	-	-	-	PfkB
GDHHQS2_k127_6447695_27	1120950.KB892809_gene1618	6.027e-40	160.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4DRU4@85009|Propionibacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS2_k127_6447695_15	324602.Caur_3337	5.013e-60	221.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi,374T6@32061|Chloroflexia	200795|Chloroflexi	F	PFAM adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS2_k127_6447695_7	158189.SpiBuddy_2428	1.024e-100	337.0	COG1079@1|root,COG1079@2|Bacteria,2J6HU@203691|Spirochaetes	203691|Spirochaetes	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_6447695_6	158189.SpiBuddy_2429	1.161e-104	353.0	COG4603@1|root,COG4603@2|Bacteria,2JAG2@203691|Spirochaetes	203691|Spirochaetes	P	transport system permease	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS2_k127_6447695_2	688269.Theth_1224	1.942e-154	503.0	COG3845@1|root,COG3845@2|Bacteria,2GBZ4@200918|Thermotogae	200918|Thermotogae	S	PFAM ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS2_k127_6447695_4	158190.SpiGrapes_1419	9.78e-128	417.0	COG1744@1|root,COG1744@2|Bacteria,2J6CM@203691|Spirochaetes	203691|Spirochaetes	S	basic membrane	bmpA-1	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS2_k127_6497991_7	118168.MC7420_7038	3.344e-112	401.0	COG0515@1|root,COG2114@1|root,COG5635@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
GDHHQS2_k127_6497991_47	504728.K649_10085	1.141e-08	69.0	COG2319@1|root,COG2319@2|Bacteria,1WK2V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GDHHQS2_k127_6497991_29	1382356.JQMP01000003_gene1897	5.465e-46	172.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS2_k127_6497991_15	1121943.KB899997_gene1720	1.185e-85	293.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS2_k127_6497991_39	189426.PODO_02900	4.227e-26	114.0	COG3797@1|root,COG3797@2|Bacteria,1VGNF@1239|Firmicutes,4HPKZ@91061|Bacilli,274WF@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS2_k127_6497991_30	1121015.N789_12055	2.275e-45	175.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria	1224|Proteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
GDHHQS2_k127_6497991_22	446466.Cfla_0507	6.874e-60	217.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS2_k127_6497991_45	1254432.SCE1572_50135	2.342e-14	87.0	29XGE@1|root,30J6W@2|Bacteria,1R0E6@1224|Proteobacteria,43CWN@68525|delta/epsilon subdivisions,2WUSC@28221|Deltaproteobacteria,2Z1N5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6497991_28	926569.ANT_11280	5.465e-46	172.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS2_k127_6497991_14	1192034.CAP_8753	7.419e-87	298.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS2_k127_6497991_44	326427.Cagg_0497	5.187e-16	82.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS2_k127_6497991_1	316274.Haur_2748	1.588e-214	681.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_6497991_10	933262.AXAM01000013_gene1312	1.032e-93	317.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2MIUS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GDHHQS2_k127_6497991_46	264732.Moth_1227	1.619e-09	63.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS2_k127_6497991_19	326427.Cagg_1104	3.555e-65	234.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS2_k127_6497991_18	1121015.N789_03735	3.508e-74	258.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GDHHQS2_k127_6497991_8	926569.ANT_06590	1.814e-109	361.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS2_k127_6497991_0	926569.ANT_06600	6.214e-268	919.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_6497991_4	1307761.L21SP2_0103	1.888e-155	508.0	COG0366@1|root,COG0366@2|Bacteria,2J6AH@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Alpha amylase, catalytic domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS2_k127_6497991_31	926569.ANT_06610	3.916e-44	168.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS2_k127_6497991_16	690585.JNNU01000002_gene5027	3.974e-76	262.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria,4BAGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GDHHQS2_k127_6497991_50	1114972.AUAW01000019_gene2054	1.009e-07	62.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,3F3R2@33958|Lactobacillaceae	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS2_k127_6497991_26	926569.ANT_30130	4.373e-53	201.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS2_k127_6497991_48	91464.S7335_2669	1.919e-08	66.0	COG0739@1|root,COG0739@2|Bacteria,1G03M@1117|Cyanobacteria,1GZYE@1129|Synechococcus	1117|Cyanobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_6497991_49	240292.Ava_1453	2.146e-08	64.0	2ERGR@1|root,33J29@2|Bacteria,1GDDN@1117|Cyanobacteria,1HRUU@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6497991_38	479434.Sthe_0368	9.885e-27	114.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,27XFQ@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
GDHHQS2_k127_6497991_27	1487923.DP73_20280	1.523e-47	180.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS2_k127_6497991_34	648757.Rvan_1044	4.851e-32	137.0	COG0596@1|root,COG2267@1|root,COG0596@2|Bacteria,COG2267@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS2_k127_6497991_3	1183438.GKIL_1560	2.624e-160	526.0	COG0531@1|root,COG0531@2|Bacteria,1G33D@1117|Cyanobacteria	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_6497991_32	1242864.D187_003106	4.386e-40	161.0	COG0654@1|root,COG1562@1|root,COG0654@2|Bacteria,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Squalene phytoene synthase	fdfT	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
GDHHQS2_k127_6497991_43	748658.KB907312_gene1825	1.788e-18	89.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RZDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS2_k127_6497991_13	926550.CLDAP_03470	2.23e-88	301.0	COG0010@1|root,COG0010@2|Bacteria,2G5N5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS2_k127_6497991_41	479434.Sthe_3270	1.553e-19	100.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6497991_11	1379698.RBG1_1C00001G0533	1.063e-90	312.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6497991_40	96561.Dole_1930	2.198e-22	104.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_6497991_9	926569.ANT_05540	6.86e-97	327.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS2_k127_6497991_23	756067.MicvaDRAFT_4069	2.735e-58	210.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,1H9IP@1150|Oscillatoriales	1117|Cyanobacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS2_k127_6497991_52	1123388.AQWU01000040_gene485	3.329e-05	51.0	COG0375@1|root,COG0375@2|Bacteria,1WKU7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GDHHQS2_k127_6497991_20	926569.ANT_19390	7.3e-62	221.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS2_k127_6497991_25	926569.ANT_19400	6.821e-54	198.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS2_k127_6497991_21	521003.COLINT_03356	3.082e-61	219.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4CYEJ@84998|Coriobacteriia	84998|Coriobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_6497991_6	512565.AMIS_7990	7.061e-146	471.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DAII@85008|Micromonosporales	201174|Actinobacteria	E	Cys met metabolism pyridoxal-phosphate-dependent	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
GDHHQS2_k127_6497991_51	1128421.JAGA01000002_gene678	1.222e-07	63.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GDHHQS2_k127_6497991_24	1382306.JNIM01000001_gene514	1.436e-55	214.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
GDHHQS2_k127_6497991_2	1128421.JAGA01000004_gene2611	4.115e-171	550.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS2_k127_6497991_33	1415775.U729_1740	1.526e-32	136.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,24IMA@186801|Clostridia,36G15@31979|Clostridiaceae	186801|Clostridia	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GDHHQS2_k127_6497991_36	926550.CLDAP_06980	5.965e-29	124.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
GDHHQS2_k127_6497991_35	309801.trd_A0237	2.503e-30	126.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi	200795|Chloroflexi	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6497991_5	243231.GSU0493	1.744e-148	484.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,43TYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS2_k127_6497991_12	1123511.KB905851_gene3495	1.073e-88	303.0	COG0111@1|root,COG2150@1|root,COG0111@2|Bacteria,COG2150@2|Bacteria,1V410@1239|Firmicutes,4H2KQ@909932|Negativicutes	909932|Negativicutes	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS2_k127_6497991_42	1239962.C943_03877	1.142e-18	98.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
GDHHQS2_k127_6497991_37	330214.NIDE3360	8.242e-28	126.0	COG0823@1|root,COG0823@2|Bacteria,3J0U9@40117|Nitrospirae	40117|Nitrospirae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_6497991_17	357808.RoseRS_2229	4.192e-76	281.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS2_k127_6668178_29	479434.Sthe_1843	3.807e-24	107.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS2_k127_6668178_28	43989.cce_2329	3.405e-25	108.0	2CBZI@1|root,339ZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6668178_36	1033743.CAES01000033_gene1053	3.46e-15	88.0	COG3794@1|root,COG4346@1|root,COG5650@1|root,COG3794@2|Bacteria,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4ISHD@91061|Bacilli,26SCF@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	F5_F8_type_C,GT87,PMT,PMT_2,PMT_4TMC
GDHHQS2_k127_6668178_41	555779.Dthio_PD2908	5.142e-05	55.0	COG3271@1|root,COG3271@2|Bacteria,1Q1Q5@1224|Proteobacteria,42U5R@68525|delta/epsilon subdivisions,2WQE7@28221|Deltaproteobacteria,2MGN7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
GDHHQS2_k127_6668178_30	926569.ANT_14090	5.65e-22	102.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
GDHHQS2_k127_6668178_33	926569.ANT_15080	1.022e-18	98.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS2_k127_6668178_15	761193.Runsl_5147	2.385e-43	166.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,47MUD@768503|Cytophagia	976|Bacteroidetes	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
GDHHQS2_k127_6668178_39	869210.Marky_1036	4.402e-09	59.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS2_k127_6668178_0	1307436.PBF_10442	2.504e-252	802.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus	91061|Bacilli	P	P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS2_k127_6668178_4	926569.ANT_29200	5.605e-97	349.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GDHHQS2_k127_6668178_18	1121423.JONT01000011_gene237	2.439e-37	151.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,261D5@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS2_k127_6668178_16	44251.PDUR_12810	5.584e-39	156.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS2_k127_6668178_24	293826.Amet_3607	5.263e-26	118.0	COG1307@1|root,COG1307@2|Bacteria,1UZ7P@1239|Firmicutes,25BCK@186801|Clostridia,36WDF@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS2_k127_6668178_14	1121423.JONT01000011_gene237	1.004e-50	190.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,261D5@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS2_k127_6668178_23	42256.RradSPS_3086	2.934e-31	127.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS2_k127_6668178_43	1434325.AZQN01000001_gene513	0.0004358	48.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes,47SPS@768503|Cytophagia	976|Bacteroidetes	S	VanZ like family	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS2_k127_6668178_11	485913.Krac_10294	6.579e-61	223.0	COG1160@1|root,COG3597@1|root,COG1160@2|Bacteria,COG3597@2|Bacteria,2G9CM@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
GDHHQS2_k127_6668178_31	240015.ACP_0160	1.042e-20	110.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
GDHHQS2_k127_6668178_10	383372.Rcas_3420	2.466e-72	280.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
GDHHQS2_k127_6668178_9	357808.RoseRS_0484	5.917e-76	289.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
GDHHQS2_k127_6668178_17	1125863.JAFN01000001_gene2345	8.469e-38	166.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS2_k127_6668178_12	1499967.BAYZ01000015_gene6576	3.309e-54	220.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_3
GDHHQS2_k127_6668178_26	644282.Deba_2254	2.307e-25	125.0	COG3852@1|root,COG4753@1|root,COG3852@2|Bacteria,COG4753@2|Bacteria,1NTTH@1224|Proteobacteria,43CP2@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS2_k127_6668178_19	926569.ANT_30860	1.091e-36	147.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS2_k127_6668178_7	926550.CLDAP_16220	9.015e-81	284.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6668178_40	1125863.JAFN01000001_gene1896	2.192e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1Q9KF@1224|Proteobacteria,430JN@68525|delta/epsilon subdivisions,2WVMG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_6668178_42	864702.OsccyDRAFT_2992	0.0002199	50.0	COG1413@1|root,COG1413@2|Bacteria,1GF6C@1117|Cyanobacteria,1HGH8@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS2_k127_6668178_6	1540257.JQMW01000012_gene2642	1.443e-84	287.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,2482S@186801|Clostridia,36GH9@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
GDHHQS2_k127_6668178_5	383372.Rcas_4271	9.185e-86	297.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_6668178_35	762948.HMPREF0733_10212	2.001e-17	85.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,1WA3U@1268|Micrococcaceae	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS2_k127_6668178_25	926569.ANT_12610	2.271e-25	108.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS2_k127_6668178_32	1173263.Syn7502_01511	4.897e-20	98.0	COG0515@1|root,COG0515@2|Bacteria,1GA6I@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS2_k127_6668178_20	926550.CLDAP_14450	2.728e-34	141.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS2_k127_6668178_38	1397699.JNIS01000001_gene863	3.22e-11	70.0	COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,3WFMT@539002|Bacillales incertae sedis	91061|Bacilli	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
GDHHQS2_k127_6668178_3	926569.ANT_14260	2.764e-108	359.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi	200795|Chloroflexi	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS2_k127_6668178_1	926569.ANT_14270	1.137e-139	451.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS2_k127_6668178_13	1191523.MROS_1522	6.362e-51	194.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS2_k127_6668178_21	530564.Psta_3376	5.493e-33	134.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS2_k127_6668178_2	926569.ANT_14280	6.491e-110	369.0	COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS2_k127_6668178_37	305900.GV64_11420	4.121e-15	82.0	290RU@1|root,2ZNDZ@2|Bacteria,1P98B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6668178_27	525904.Tter_1090	2.799e-25	109.0	COG1950@1|root,COG1950@2|Bacteria,2NQ43@2323|unclassified Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
GDHHQS2_k127_6668178_22	485913.Krac_2087	8.223e-32	132.0	COG0491@1|root,COG0491@2|Bacteria,2G78X@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_6668178_8	420662.Mpe_A0106	4.687e-76	273.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria	1224|Proteobacteria	S	Von willebrand factor, type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GDHHQS2_k127_6757311_29	316274.Haur_1012	1.044e-61	225.0	COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2G8UQ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6757311_45	391612.CY0110_10747	3.86e-40	163.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Response_reg
GDHHQS2_k127_6757311_3	926569.ANT_19600	1.06e-142	463.0	COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS2_k127_6757311_35	1379698.RBG1_1C00001G0918	1.282e-56	207.0	COG2189@1|root,COG2189@2|Bacteria,2NQUB@2323|unclassified Bacteria	2|Bacteria	L	DNA methylase	dpnA	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS2_k127_6757311_34	452637.Oter_0576	1.125e-56	207.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
GDHHQS2_k127_6757311_72	665571.STHERM_c17800	7.101e-09	67.0	COG0457@1|root,COG0457@2|Bacteria	665571.STHERM_c17800|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_56	383372.Rcas_2392	8.27e-27	128.0	COG0631@1|root,COG0631@2|Bacteria,2G8I1@200795|Chloroflexi,375BS@32061|Chloroflexia	32061|Chloroflexia	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS2_k127_6757311_51	330214.NIDE1115	7.6e-34	151.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Trypsin_2
GDHHQS2_k127_6757311_55	1379698.RBG1_1C00001G0797	4.883e-28	119.0	COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS2_k127_6757311_27	329726.AM1_2062	5.407e-63	224.0	2C03A@1|root,2Z86B@2|Bacteria,1G2Y7@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4291
GDHHQS2_k127_6757311_19	926550.CLDAP_20970	1.596e-80	276.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_57	457570.Nther_0156	3.335e-26	124.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS2_k127_6757311_31	861299.J421_4449	2.123e-60	233.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6757311_33	383372.Rcas_0525	3.935e-57	223.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_6757311_37	326427.Cagg_3772	3.086e-55	217.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS2_k127_6757311_61	1502851.FG93_02181	2.194e-24	108.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,3JR51@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	glycosylase i	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS2_k127_6757311_1	526227.Mesil_1001	9.494e-173	561.0	COG1132@1|root,COG1132@2|Bacteria,1WMBB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS2_k127_6757311_65	67593.Physo156057	1.837e-19	100.0	KOG4351@1|root,KOG4351@2759|Eukaryota,3Q8PI@4776|Peronosporales	4776|Peronosporales	S	Ig-like domain from next to BRCA1 gene	-	-	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1
GDHHQS2_k127_6757311_46	373994.Riv7116_4482	1.158e-38	151.0	COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1HK8V@1161|Nostocales	1117|Cyanobacteria	J	TIGRFAM endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS2_k127_6757311_69	1333523.L593_06050	7.057e-11	68.0	COG5410@1|root,arCOG09550@2157|Archaea,2XW1V@28890|Euryarchaeota,23Z33@183963|Halobacteria	183963|Halobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_6	926569.ANT_04230	1.426e-132	434.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS2_k127_6757311_20	448385.sce5969	1.182e-75	259.0	COG1409@1|root,COG1409@2|Bacteria,1N7CQ@1224|Proteobacteria,430CA@68525|delta/epsilon subdivisions,2WW6B@28221|Deltaproteobacteria,2YWTS@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS2_k127_6757311_75	661367.LLO_2946	1.84e-05	51.0	COG1409@1|root,COG1409@2|Bacteria,1N7CQ@1224|Proteobacteria,1T7BB@1236|Gammaproteobacteria,1JF5W@118969|Legionellales	118969|Legionellales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS2_k127_6757311_59	1123242.JH636438_gene5786	4.645e-25	109.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	MA20_35640	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
GDHHQS2_k127_6757311_44	195250.CM001776_gene2940	3.262e-40	167.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1G1GS@1117|Cyanobacteria,1GYDA@1129|Synechococcus	1117|Cyanobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
GDHHQS2_k127_6757311_28	518766.Rmar_0501	1.21e-62	225.0	COG3769@1|root,COG3769@2|Bacteria,4P1MD@976|Bacteroidetes	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
GDHHQS2_k127_6757311_10	926569.ANT_04390	1.055e-103	352.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS2_k127_6757311_32	324925.Ppha_2788	2.615e-57	203.0	COG1970@1|root,COG1970@2|Bacteria,1FF5D@1090|Chlorobi	1090|Chlorobi	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS2_k127_6757311_2	926569.ANT_11040	1.731e-169	550.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS2_k127_6757311_74	1123256.KB907940_gene194	9.537e-07	59.0	COG3391@1|root,COG3391@2|Bacteria,1P03Z@1224|Proteobacteria	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_70	118166.JH976537_gene2998	9.958e-10	67.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
GDHHQS2_k127_6757311_30	383372.Rcas_1479	4.623e-61	223.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_6757311_0	218851.Aquca_017_00087.1	4.612e-234	754.0	COG4354@1|root,KOG2119@2759|Eukaryota,37JKE@33090|Viridiplantae,3GG94@35493|Streptophyta	35493|Streptophyta	G	Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide	-	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0006082,GO:0006629,GO:0007275,GO:0007399,GO:0007417,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008422,GO:0009056,GO:0009987,GO:0015926,GO:0016020,GO:0016021,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0019752,GO:0021953,GO:0021954,GO:0022008,GO:0030154,GO:0030182,GO:0031224,GO:0032501,GO:0032502,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0071704,GO:1901135,GO:1901136,GO:1901360,GO:1901575,GO:1901615,GO:1901657,GO:1901658	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
GDHHQS2_k127_6757311_22	472759.Nhal_1492	2.664e-72	256.0	COG1262@1|root,COG1672@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,1RAMU@1224|Proteobacteria,1S87Q@1236|Gammaproteobacteria,1X2AR@135613|Chromatiales	135613|Chromatiales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS2_k127_6757311_40	575788.VS_II0095	5.892e-47	173.0	COG0346@1|root,COG0346@2|Bacteria,1N0VU@1224|Proteobacteria,1S7C0@1236|Gammaproteobacteria,1XWYI@135623|Vibrionales	135623|Vibrionales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GDHHQS2_k127_6757311_23	1499967.BAYZ01000060_gene6005	2.005e-71	246.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS2_k127_6757311_4	1128421.JAGA01000002_gene1693	6.191e-139	449.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS2_k127_6757311_15	1128421.JAGA01000002_gene1692	4.452e-88	298.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS2_k127_6757311_12	1128421.JAGA01000002_gene1691	4.348e-92	309.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS2_k127_6757311_36	1128421.JAGA01000002_gene1525	3.854e-56	204.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS2_k127_6757311_39	1128421.JAGA01000002_gene1525	6.162e-52	192.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS2_k127_6757311_63	67257.JODR01000017_gene4472	4.776e-22	100.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
GDHHQS2_k127_6757311_58	1006004.GBAG_3926	5.158e-26	108.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspA	GO:0001072,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS2_k127_6757311_7	643473.KB235930_gene4348	8.41e-129	426.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HMP2@1161|Nostocales	1117|Cyanobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS2_k127_6757311_42	926569.ANT_01150	5.436e-43	164.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS2_k127_6757311_76	1463917.JODC01000007_gene7287	0.0002737	51.0	COG3393@1|root,COG3393@2|Bacteria,2GMQC@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	FR47
GDHHQS2_k127_6757311_43	555079.Toce_2076	1.342e-42	161.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_6757311_9	309799.DICTH_0359	1.095e-111	376.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GDHHQS2_k127_6757311_41	1173029.JH980292_gene2960	7.09e-46	181.0	COG0642@1|root,COG2205@2|Bacteria	1173029.JH980292_gene2960|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_11	1173029.JH980292_gene2959	3.539e-101	346.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
GDHHQS2_k127_6757311_64	1396418.BATQ01000136_gene3698	1.757e-20	97.0	COG2453@1|root,COG2453@2|Bacteria	2|Bacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,Y_phosphatase
GDHHQS2_k127_6757311_53	926569.ANT_19040	2.708e-29	120.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_24	926569.ANT_19030	3.376e-70	243.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS2_k127_6757311_38	926569.ANT_26640	2.498e-54	211.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS2_k127_6757311_48	5341.XP_007333059.1	4.429e-37	153.0	COG2234@1|root,2R701@2759|Eukaryota,38G6N@33154|Opisthokonta,3NX20@4751|Fungi,3V3B4@5204|Basidiomycota,226PC@155619|Agaricomycetes,3W8ZX@5338|Agaricales	4751|Fungi	O	Belongs to the peptidase M28 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_6757311_67	365528.KB891102_gene4264	1.484e-13	84.0	COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6757311_68	926550.CLDAP_32470	4.507e-13	83.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_6757311_17	439235.Dalk_4823	5.633e-83	284.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42PE4@68525|delta/epsilon subdivisions,2WK83@28221|Deltaproteobacteria,2MPWY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS2_k127_6757311_18	42256.RradSPS_2328	1.112e-80	279.0	COG4424@1|root,COG4424@2|Bacteria,2HETZ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
GDHHQS2_k127_6757311_25	1229780.BN381_80244	2.908e-69	250.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,3UXIU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS2_k127_6757311_21	357808.RoseRS_0470	2.423e-72	265.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2G90N@200795|Chloroflexi,376SX@32061|Chloroflexia	32061|Chloroflexia	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_6757311_26	671143.DAMO_0728	6.093e-66	239.0	2DM5Q@1|root,31TN4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
GDHHQS2_k127_6757311_71	349106.PsycPRwf_1130	1.045e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,1NKN2@1224|Proteobacteria,1SGR0@1236|Gammaproteobacteria,3NNQN@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
GDHHQS2_k127_6757311_66	525904.Tter_1002	7.732e-15	80.0	COG1974@1|root,COG1974@2|Bacteria,2NPJG@2323|unclassified Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS2_k127_6757311_5	1499967.BAYZ01000152_gene1393	2.781e-138	449.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	mdeA	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS2_k127_6757311_47	485913.Krac_2535	1.89e-38	149.0	COG0778@1|root,COG0778@2|Bacteria,2G79R@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS2_k127_6757311_8	765420.OSCT_2914	1.48e-125	419.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS2_k127_6757311_60	1463856.JOHY01000006_gene204	1.395e-24	113.0	COG1840@1|root,COG1840@2|Bacteria,2GUQY@201174|Actinobacteria	201174|Actinobacteria	P	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6757311_50	316274.Haur_4785	3.152e-35	143.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2
GDHHQS2_k127_6757311_54	316274.Haur_4785	4.775e-28	121.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2
GDHHQS2_k127_6757311_62	309801.trd_A0237	7.623e-24	108.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi	200795|Chloroflexi	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_6757311_16	926569.ANT_05520	7.028e-84	290.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS2_k127_6757311_13	748449.Halha_1373	2.25e-89	305.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,3WBWU@53433|Halanaerobiales	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
GDHHQS2_k127_6757311_52	1133849.O3I_004270	2.894e-30	124.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_6757311_73	926560.KE387023_gene1206	6.405e-08	61.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS2_k127_6757311_14	215803.DB30_3379	2.542e-89	306.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,438ES@68525|delta/epsilon subdivisions,2X3PR@28221|Deltaproteobacteria,2YWSV@29|Myxococcales	28221|Deltaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
GDHHQS2_k127_6757311_49	395493.BegalDRAFT_0269	1.6e-36	154.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,1T4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
GDHHQS2_k127_6911889_3	1191523.MROS_1542	2.132e-62	218.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GDHHQS2_k127_6911889_14	452637.Oter_2041	5.081e-16	83.0	COG1917@1|root,COG1917@2|Bacteria,46WJU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS2_k127_6911889_4	316274.Haur_3817	3.139e-53	199.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS2_k127_6911889_7	926569.ANT_09860	3.689e-27	118.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GDHHQS2_k127_6911889_21	195253.Syn6312_1483	4.569e-08	57.0	COG1598@1|root,COG1598@2|Bacteria,1G9W5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6911889_20	43989.cce_1219	3.152e-10	63.0	COG1724@1|root,COG1724@2|Bacteria,1G90Q@1117|Cyanobacteria,3KK9X@43988|Cyanothece	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_6911889_0	926569.ANT_16290	6.47e-252	795.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
GDHHQS2_k127_6911889_2	479434.Sthe_2033	4.881e-105	355.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS2_k127_6911889_6	105559.Nwat_1966	2.664e-32	126.0	2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria,1SS40@1236|Gammaproteobacteria,1X173@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6911889_9	247490.KSU1_C0079	4.646e-20	91.0	2E90H@1|root,31X4M@2|Bacteria,2J4J2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_6911889_1	383372.Rcas_2605	2.411e-202	658.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,376FV@32061|Chloroflexia	32061|Chloroflexia	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
GDHHQS2_k127_6911889_8	1125863.JAFN01000001_gene2242	1.206e-26	111.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,42VRN@68525|delta/epsilon subdivisions,2WS04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
GDHHQS2_k127_6911889_5	525897.Dbac_2532	6.133e-41	154.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,42UX7@68525|delta/epsilon subdivisions,2WR46@28221|Deltaproteobacteria,2MFZZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM addiction module toxin, Txe YoeB family	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
GDHHQS2_k127_6911889_17	313596.RB2501_12022	1.332e-13	82.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_6911889_15	368407.Memar_0776	6.868e-15	86.0	arCOG03383@1|root,arCOG03383@2157|Archaea,2Y7A4@28890|Euryarchaeota,2NB4Y@224756|Methanomicrobia	224756|Methanomicrobia	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_6911889_13	756067.MicvaDRAFT_4644	2.256e-17	94.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria,1HCNX@1150|Oscillatoriales	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_6911889_12	215803.DB30_3986	1.15e-17	95.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_6911889_10	483219.LILAB_06945	2.057e-18	97.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_6911889_16	629773.AORY01000011_gene1926	3.389e-14	84.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_6911889_11	489825.LYNGBM3L_30140	5.993e-18	87.0	COG2442@1|root,COG2442@2|Bacteria,1G6VW@1117|Cyanobacteria,1HBPI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS2_k127_6911889_19	489825.LYNGBM3L_49150	3.515e-11	69.0	COG4634@1|root,COG4634@2|Bacteria,1G84D@1117|Cyanobacteria,1HCB8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_124	927677.ALVU02000002_gene406	4.343e-17	87.0	COG2842@1|root,COG2842@2|Bacteria,1GB1T@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
GDHHQS2_k127_7092788_79	313612.L8106_29980	2.178e-54	215.0	COG2801@1|root,COG2801@2|Bacteria,1G1WB@1117|Cyanobacteria,1H9SN@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,Mu-transpos_C,rve
GDHHQS2_k127_7092788_56	1499967.BAYZ01000048_gene2702	3.229e-78	271.0	COG3752@1|root,COG3752@2|Bacteria,2NR3R@2323|unclassified Bacteria	2|Bacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	yfhH	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	DUF1295
GDHHQS2_k127_7092788_42	926550.CLDAP_29040	2.177e-94	319.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS2_k127_7092788_9	1121104.AQXH01000001_gene1465	1.345e-224	710.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes	976|Bacteroidetes	E	TIGRFAM oligoendopeptidase, M3 family	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS2_k127_7092788_95	1121272.KB903249_gene2255	4.871e-35	139.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS2_k127_7092788_45	765912.Thimo_1246	2.194e-89	304.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS2_k127_7092788_85	926569.ANT_23510	2.377e-43	173.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GDHHQS2_k127_7092788_101	1455608.JDTH01000002_gene1185	3.312e-29	121.0	arCOG11894@1|root,arCOG11894@2157|Archaea,2Y0MW@28890|Euryarchaeota,23Y1R@183963|Halobacteria	183963|Halobacteria	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_57	324602.Caur_2455	8.602e-77	264.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
GDHHQS2_k127_7092788_6	926550.CLDAP_15350	1.663e-233	755.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
GDHHQS2_k127_7092788_40	1499967.BAYZ01000186_gene3970	5.294e-100	339.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_7092788_39	1125863.JAFN01000001_gene322	4.391e-107	356.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS2_k127_7092788_36	1499967.BAYZ01000069_gene1838	4.031e-111	382.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS2_k127_7092788_61	926569.ANT_24620	5.042e-72	270.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
GDHHQS2_k127_7092788_8	926569.ANT_05040	6.046e-232	740.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS2_k127_7092788_109	47716.JOFH01000029_gene3194	5.183e-26	118.0	COG0726@1|root,COG1215@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Polysacc_deac_1
GDHHQS2_k127_7092788_73	70601.3257463	3.505e-57	211.0	COG2309@1|root,arCOG01890@2157|Archaea,2XU28@28890|Euryarchaeota,243WP@183968|Thermococci	183968|Thermococci	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
GDHHQS2_k127_7092788_49	765420.OSCT_2097	1.16e-86	301.0	COG0745@1|root,COG2203@1|root,COG2267@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2267@2|Bacteria,2GAKU@200795|Chloroflexi,376PC@32061|Chloroflexia	32061|Chloroflexia	T	Pfam:DUF2305	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_7092788_60	875328.JDM601_0482	6.29e-75	264.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,23871@1762|Mycobacteriaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS2_k127_7092788_126	653733.Selin_0064	9.259e-15	81.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3852@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS2_k127_7092788_58	926569.ANT_00640	1.521e-75	257.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GDHHQS2_k127_7092788_70	926550.CLDAP_05540	3.029e-58	220.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS2_k127_7092788_133	512565.AMIS_30450	6.933e-06	56.0	2FJMA@1|root,344HE@2|Bacteria,2GTDW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_13	1382306.JNIM01000001_gene2376	1.576e-194	620.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
GDHHQS2_k127_7092788_99	479434.Sthe_0381	1.168e-32	137.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,27XXM@189775|Thermomicrobia	189775|Thermomicrobia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS2_k127_7092788_38	383372.Rcas_4084	1.051e-109	363.0	COG1209@1|root,COG1209@2|Bacteria,2GBKU@200795|Chloroflexi,3781T@32061|Chloroflexia	32061|Chloroflexia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS2_k127_7092788_19	316274.Haur_4591	1.593e-160	514.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_7092788_111	525367.HMPREF0556_10090	3.022e-25	112.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,26JSV@186820|Listeriaceae	91061|Bacilli	S	UPF0316 protein	yebE	-	-	-	-	-	-	-	-	-	-	-	DUF2179
GDHHQS2_k127_7092788_130	1380390.JIAT01000010_gene4795	4.544e-09	66.0	2AYFR@1|root,31QJ0@2|Bacteria,2HPVB@201174|Actinobacteria,4CR9I@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
GDHHQS2_k127_7092788_135	1134445.AJJM01000057_gene2368	8.17e-05	54.0	COG0454@1|root,COG0456@2|Bacteria,2GMXI@201174|Actinobacteria	201174|Actinobacteria	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_7092788_35	926569.ANT_30410	1.363e-111	378.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_7092788_69	1121930.AQXG01000010_gene3044	4.229e-61	221.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes	976|Bacteroidetes	S	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
GDHHQS2_k127_7092788_15	926569.ANT_11050	1.104e-172	551.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS2_k127_7092788_67	351607.Acel_1240	7.707e-65	231.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS2_k127_7092788_127	485913.Krac_5906	2.827e-13	76.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GDHHQS2_k127_7092788_121	926569.ANT_16590	9.399e-18	90.0	29ATW@1|root,2ZXTA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_122	1121272.KB903283_gene4876	1.148e-17	93.0	COG1073@1|root,COG1073@2|Bacteria,2IPZT@201174|Actinobacteria,4DFQX@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4
GDHHQS2_k127_7092788_53	1382306.JNIM01000001_gene1028	2.035e-82	284.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS2_k127_7092788_30	926550.CLDAP_01880	1.047e-118	393.0	COG3664@1|root,COG3664@2|Bacteria,2G82D@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_77	1487953.JMKF01000061_gene4797	2.524e-55	199.0	COG0563@1|root,COG0563@2|Bacteria,1G696@1117|Cyanobacteria,1HB35@1150|Oscillatoriales	1117|Cyanobacteria	F	Shikimate kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PduV-EutP,SKI
GDHHQS2_k127_7092788_43	926550.CLDAP_25450	7.185e-91	311.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS2_k127_7092788_96	390874.Tpet_0324	6.362e-35	143.0	COG0834@1|root,COG0834@2|Bacteria,2GC3G@200918|Thermotogae	200918|Thermotogae	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GDHHQS2_k127_7092788_94	926569.ANT_23030	6.879e-36	150.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
GDHHQS2_k127_7092788_18	926569.ANT_11210	2.734e-161	524.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS2_k127_7092788_2	1120973.AQXL01000116_gene290	2.258e-313	983.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS2_k127_7092788_89	1197130.BAFM01000009_gene1696	3.71e-42	168.0	COG2041@1|root,arCOG00264@2157|Archaea,2XVB4@28890|Euryarchaeota,23TED@183963|Halobacteria	183963|Halobacteria	S	COG2041 Sulfite oxidase and related enzymes	soxA1	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS2_k127_7092788_78	266265.Bxe_A2751	2.723e-55	203.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VK8V@28216|Betaproteobacteria,1K1J7@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Coenzyme A transferase	gctA	-	2.8.3.12,2.8.3.5	ko:K01028,ko:K01039	ko00072,ko00280,ko00643,ko00650,ko01120,map00072,map00280,map00643,map00650,map01120	-	R00410,R04000,R05509	RC00012,RC00014,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS2_k127_7092788_66	215803.DB30_8096	2.324e-65	234.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NWG@68525|delta/epsilon subdivisions,2WKEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GDHHQS2_k127_7092788_100	1121403.AUCV01000026_gene2358	2.316e-32	136.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS2_k127_7092788_112	1122222.AXWR01000004_gene1761	1.781e-24	110.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS2_k127_7092788_51	926569.ANT_15210	1.084e-84	295.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS2_k127_7092788_86	926569.ANT_30470	5.96e-43	173.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
GDHHQS2_k127_7092788_20	383372.Rcas_3183	5.149e-157	512.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi,3751Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
GDHHQS2_k127_7092788_116	867845.KI911784_gene2572	7.493e-22	109.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GDHHQS2_k127_7092788_123	1487953.JMKF01000073_gene3652	3.172e-17	94.0	COG2340@1|root,COG2340@2|Bacteria,1G4UZ@1117|Cyanobacteria,1HAAV@1150|Oscillatoriales	1117|Cyanobacteria	Q	Scp-like extracellular	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HemolysinCabind,PPC
GDHHQS2_k127_7092788_44	926569.ANT_06870	1.787e-89	306.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS2_k127_7092788_65	1128421.JAGA01000002_gene1877	5.482e-67	246.0	COG0793@1|root,COG0793@2|Bacteria,2NNKC@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
GDHHQS2_k127_7092788_59	926550.CLDAP_01850	3.083e-75	263.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GDHHQS2_k127_7092788_41	926560.KE387023_gene2057	5.058e-97	326.0	COG1131@1|root,COG1131@2|Bacteria,1WM2S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS2_k127_7092788_120	760192.Halhy_3025	1.255e-18	100.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4NUFW@976|Bacteroidetes,1IZ0P@117747|Sphingobacteriia	976|Bacteroidetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
GDHHQS2_k127_7092788_98	926550.CLDAP_06590	6.976e-33	130.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS2_k127_7092788_4	926569.ANT_26670	3.377e-254	793.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS2_k127_7092788_12	926569.ANT_25100	5.454e-199	637.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS2_k127_7092788_105	926569.ANT_25090	2.594e-27	125.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_14	1121468.AUBR01000034_gene1374	1.431e-180	587.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS2_k127_7092788_5	926569.ANT_20890	3.088e-241	762.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS2_k127_7092788_17	42256.RradSPS_3022	6.503e-169	548.0	COG0166@1|root,COG0166@2|Bacteria,2HFZ9@201174|Actinobacteria,4CPPV@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS2_k127_7092788_136	345341.KUTG_01098	8.693e-05	55.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DYW9@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
GDHHQS2_k127_7092788_24	1382356.JQMP01000004_gene284	1.973e-137	468.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
GDHHQS2_k127_7092788_33	926569.ANT_01840	1.048e-113	376.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GDHHQS2_k127_7092788_1	926569.ANT_01830	0.0	1218.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS2_k127_7092788_62	765952.PUV_10050	4.023e-71	251.0	COG0266@1|root,COG0266@2|Bacteria,2JGIB@204428|Chlamydiae	204428|Chlamydiae	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS2_k127_7092788_75	290317.Cpha266_2433	6.809e-56	210.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
GDHHQS2_k127_7092788_80	326427.Cagg_1130	1.785e-51	190.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS2_k127_7092788_93	383372.Rcas_2148	6.031e-36	151.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS2_k127_7092788_84	326427.Cagg_1653	1.343e-43	168.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia	32061|Chloroflexia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS2_k127_7092788_131	926569.ANT_27460	5.238e-07	58.0	COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi	200795|Chloroflexi	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
GDHHQS2_k127_7092788_64	926550.CLDAP_37610	1.856e-70	250.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GDHHQS2_k127_7092788_25	926569.ANT_01730	1.532e-129	427.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS2_k127_7092788_125	693977.Deipr_0764	2.178e-16	92.0	COG3947@1|root,COG3947@2|Bacteria,1WMI5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing CheY-like receiver and SARP domains	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Response_reg
GDHHQS2_k127_7092788_103	926569.ANT_15180	7.829e-28	118.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
GDHHQS2_k127_7092788_117	204669.Acid345_0142	9.832e-21	99.0	COG1011@1|root,COG1011@2|Bacteria,3Y56D@57723|Acidobacteria,2JJQ6@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS2_k127_7092788_29	1379698.RBG1_1C00001G0703	4.672e-120	405.0	COG0124@1|root,COG0124@2|Bacteria,2NNZ7@2323|unclassified Bacteria	2|Bacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS2_k127_7092788_23	316274.Haur_0038	1.318e-137	445.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS2_k127_7092788_3	525904.Tter_0334	4.033e-257	805.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS2_k127_7092788_91	869210.Marky_2009	7.594e-38	156.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1WJ1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS2_k127_7092788_11	1382356.JQMP01000001_gene806	1.517e-205	659.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
GDHHQS2_k127_7092788_119	1128421.JAGA01000002_gene1897	1.184e-20	101.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
GDHHQS2_k127_7092788_114	316274.Haur_4979	1.341e-23	105.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,375UJ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GDHHQS2_k127_7092788_32	926569.ANT_11390	1.018e-116	383.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS2_k127_7092788_46	357808.RoseRS_1306	2.421e-89	310.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,37557@32061|Chloroflexia	32061|Chloroflexia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
GDHHQS2_k127_7092788_68	935948.KE386494_gene514	1.192e-64	239.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,42FRP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM penicillin-binding protein transpeptidase	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
GDHHQS2_k127_7092788_63	926569.ANT_13310	1.665e-70	255.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
GDHHQS2_k127_7092788_22	926569.ANT_13300	9.059e-148	484.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
GDHHQS2_k127_7092788_21	1382359.JIAL01000001_gene464	3.193e-151	491.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS2_k127_7092788_71	383372.Rcas_3157	1.956e-57	214.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi,377PJ@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
GDHHQS2_k127_7092788_72	326427.Cagg_0674	2.916e-57	214.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi,375GG@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS2_k127_7092788_50	485913.Krac_12461	2.331e-85	294.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS2_k127_7092788_26	926569.ANT_07040	2.864e-129	421.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
GDHHQS2_k127_7092788_81	926550.CLDAP_10900	5.856e-50	190.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
GDHHQS2_k127_7092788_47	926569.ANT_23020	3.373e-89	320.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_7092788_83	926569.ANT_23030	4.163e-46	181.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
GDHHQS2_k127_7092788_10	479434.Sthe_0734	2.637e-218	698.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,27XXG@189775|Thermomicrobia	189775|Thermomicrobia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS2_k127_7092788_48	926561.KB900622_gene601	4.414e-88	301.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3WAI9@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS2_k127_7092788_92	926550.CLDAP_20820	1.99e-36	146.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
GDHHQS2_k127_7092788_88	479434.Sthe_3107	2.145e-42	169.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS2_k127_7092788_76	926569.ANT_22440	1.085e-55	211.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
GDHHQS2_k127_7092788_113	926569.ANT_22430	6.04e-24	105.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS2_k127_7092788_74	926569.ANT_22420	8.026e-57	202.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS2_k127_7092788_118	1321814.HMPREF9089_01468	1.041e-20	95.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,25WPC@186806|Eubacteriaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS2_k127_7092788_104	1122221.JHVI01000021_gene2447	1.959e-27	126.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87,Mannosyl_trans2,PMT_2
GDHHQS2_k127_7092788_82	926569.ANT_25400	4.846e-47	178.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
GDHHQS2_k127_7092788_115	479434.Sthe_2034	8.514e-23	103.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GDHHQS2_k127_7092788_97	1128421.JAGA01000002_gene1413	5.195e-34	142.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
GDHHQS2_k127_7092788_27	1128421.JAGA01000001_gene2344	2.2e-124	421.0	COG4907@1|root,COG4907@2|Bacteria,2NQC3@2323|unclassified Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
GDHHQS2_k127_7092788_110	1128421.JAGA01000001_gene2343	9.683e-26	113.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
GDHHQS2_k127_7092788_108	926569.ANT_20600	2.762e-26	114.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7092788_55	926569.ANT_20590	9.587e-80	277.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
GDHHQS2_k127_7092788_106	926550.CLDAP_21430	5.737e-27	128.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
GDHHQS2_k127_7092788_137	1382356.JQMP01000001_gene1080	0.0001137	53.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi,27XHI@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS2_k127_7092788_90	326427.Cagg_2012	1.843e-39	158.0	COG1184@1|root,COG1184@2|Bacteria,2G9CC@200795|Chloroflexi,3762Q@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the eIF-2B alpha beta delta subunits family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
GDHHQS2_k127_7092788_28	926569.ANT_16960	2.429e-121	403.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS2_k127_7092788_37	926569.ANT_16950	7.805e-110	367.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS2_k127_7092788_54	1128421.JAGA01000001_gene2396	7.222e-81	280.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS2_k127_7092788_16	926550.CLDAP_10840	9.26e-172	550.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS2_k127_7092788_7	926569.ANT_10870	2.975e-233	748.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS2_k127_7092788_87	926550.CLDAP_35480	9.919e-43	175.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
GDHHQS2_k127_7092788_0	926569.ANT_10860	0.0	1722.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GDHHQS2_k127_7092788_31	926550.CLDAP_34520	1.989e-117	388.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS2_k127_7092788_52	1382306.JNIM01000001_gene914	2.535e-84	290.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS2_k127_7092788_107	316056.RPC_2465	8.541e-27	113.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,3JR9A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS2_k127_7105544_52	68570.DC74_7296	6.219e-22	98.0	2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_40	706587.Desti_4215	1.669e-45	175.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS2_k127_7105544_23	498761.HM1_2746	1.241e-79	278.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS2_k127_7105544_30	869210.Marky_2229	2.033e-69	244.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_28	696369.KI912183_gene2010	2.848e-74	259.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,24G1T@186801|Clostridia	186801|Clostridia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS2_k127_7105544_9	639283.Snov_2172	9.709e-132	429.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3EYGH@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_7105544_20	926569.ANT_31310	8.536e-87	295.0	COG1177@1|root,COG1177@2|Bacteria,2G80I@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS2_k127_7105544_18	926569.ANT_31320	5.683e-103	344.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS2_k127_7105544_7	1353531.AZNX01000003_gene2812	5.203e-159	509.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,4B8Z6@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
GDHHQS2_k127_7105544_15	1499967.BAYZ01000117_gene3320	4.535e-117	381.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS2_k127_7105544_8	1499967.BAYZ01000117_gene3321	4.535e-158	505.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisD	-	1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,Histidinol_dh
GDHHQS2_k127_7105544_11	1499967.BAYZ01000117_gene3322	5.696e-125	406.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba2	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
GDHHQS2_k127_7105544_36	756067.MicvaDRAFT_3416	7.339e-52	188.0	COG3153@1|root,COG3153@2|Bacteria,1G68Q@1117|Cyanobacteria,1HDVK@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GDHHQS2_k127_7105544_0	999611.KI421504_gene1865	7.474e-256	812.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,27ZNZ@191028|Leisingera	28211|Alphaproteobacteria	E	Sarcosine oxidase, gamma subunit family	Sardh	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GDHHQS2_k127_7105544_35	1283299.AUKG01000002_gene4309	2.852e-53	201.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
GDHHQS2_k127_7105544_66	1463820.JOGW01000005_gene3316	7.272e-09	66.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
GDHHQS2_k127_7105544_39	309801.trd_1320	2.358e-46	177.0	arCOG06048@1|root,31EJQ@2|Bacteria,2G6TM@200795|Chloroflexi,27Z2Z@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_5	1380394.JADL01000009_gene3326	1.538e-172	556.0	COG0531@1|root,COG0531@2|Bacteria,1MX13@1224|Proteobacteria,2U4NM@28211|Alphaproteobacteria,2JPBJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_7105544_37	1321815.HMPREF9193_01232	2.923e-51	191.0	COG1349@1|root,COG1349@2|Bacteria,2JAGP@203691|Spirochaetes	203691|Spirochaetes	K	transcriptional regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
GDHHQS2_k127_7105544_21	309801.trd_1319	1.043e-83	289.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_34	266117.Rxyl_0773	1.425e-56	218.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS2_k127_7105544_31	1298880.AUEV01000002_gene1744	6.848e-69	244.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria	201174|Actinobacteria	M	Choline ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
GDHHQS2_k127_7105544_50	1123405.AUMM01000032_gene1763	2.29e-25	112.0	COG0494@1|root,COG0494@2|Bacteria,1V9FI@1239|Firmicutes,4HJ1A@91061|Bacilli	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS2_k127_7105544_2	211114.JOEF01000003_gene3012	4.177e-196	638.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GDHHQS2_k127_7105544_58	886293.Sinac_0154	1.001e-16	86.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Glyoxalase
GDHHQS2_k127_7105544_57	1210884.HG799465_gene11476	4.863e-17	88.0	COG4636@1|root,COG4636@2|Bacteria,2J02G@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS2_k127_7105544_46	926550.CLDAP_16980	3.122e-29	123.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS2_k127_7105544_47	118161.KB235922_gene3231	2.262e-28	117.0	COG1598@1|root,COG1598@2|Bacteria,1G89J@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_48	391612.CY0110_10097	4.273e-27	111.0	COG1724@1|root,COG1724@2|Bacteria,1GA91@1117|Cyanobacteria,3KK77@43988|Cyanothece	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_7105544_4	1121430.JMLG01000016_gene367	2.799e-188	609.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
GDHHQS2_k127_7105544_38	1232437.KL661971_gene4896	3.379e-50	186.0	COG5012@1|root,COG5012@2|Bacteria,1RDEU@1224|Proteobacteria,43BR3@68525|delta/epsilon subdivisions,2X809@28221|Deltaproteobacteria,2MKIG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
GDHHQS2_k127_7105544_44	1337936.IJ00_01065	1.402e-30	134.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
GDHHQS2_k127_7105544_42	926554.KI912671_gene408	3.636e-38	148.0	2E4GK@1|root,32ZBS@2|Bacteria	2|Bacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
GDHHQS2_k127_7105544_6	926554.KI912671_gene402	3.395e-163	523.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GDHHQS2_k127_7105544_51	479432.Sros_4659	9.689e-24	103.0	2E5NA@1|root,330D3@2|Bacteria,2IQ91@201174|Actinobacteria,4EK6C@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
GDHHQS2_k127_7105544_24	485913.Krac_6898	3.263e-79	272.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_7105544_41	485913.Krac_1842	3.577e-45	171.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS2_k127_7105544_33	1340493.JNIF01000003_gene3428	3.577e-59	214.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS2_k127_7105544_56	1121472.AQWN01000007_gene1026	3.38e-17	92.0	COG1410@1|root,COG1410@2|Bacteria,1UYPT@1239|Firmicutes,258KD@186801|Clostridia,260WF@186807|Peptococcaceae	186801|Clostridia	E	PFAM Vitamin B12 dependent methionine synthase, activation	-	-	-	-	-	-	-	-	-	-	-	-	Met_synt_B12
GDHHQS2_k127_7105544_22	768706.Desor_3513	2.383e-83	286.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
GDHHQS2_k127_7105544_32	641107.CDLVIII_3919	3.133e-66	233.0	COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,24AQ6@186801|Clostridia,36I4M@31979|Clostridiaceae	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS2_k127_7105544_27	429009.Adeg_0345	1.691e-74	269.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42FH6@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GDHHQS2_k127_7105544_54	1320556.AVBP01000019_gene1301	9.392e-18	97.0	COG0685@1|root,COG0685@2|Bacteria,1RDXU@1224|Proteobacteria,2VGE6@28211|Alphaproteobacteria,43GZG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
GDHHQS2_k127_7105544_3	768704.Desmer_1618	1.283e-190	606.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS2_k127_7105544_29	635013.TherJR_0056	1.721e-71	255.0	COG2334@1|root,COG2334@2|Bacteria,1V2UV@1239|Firmicutes,24FTV@186801|Clostridia,263ZQ@186807|Peptococcaceae	186801|Clostridia	S	Phosphotransferase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
GDHHQS2_k127_7105544_25	926569.ANT_05580	2.031e-76	263.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS2_k127_7105544_63	358396.C445_00370	2.648e-10	72.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota,23SIB@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GDHHQS2_k127_7105544_49	1349767.GJA_2367	6.482e-27	123.0	COG0726@1|root,COG4249@1|root,COG0726@2|Bacteria,COG4249@2|Bacteria,1PJQG@1224|Proteobacteria,2VIG8@28216|Betaproteobacteria,4757C@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Polysaccharide deacetylase	nodB	-	3.5.1.104,3.5.1.41	ko:K01452,ko:K14659,ko:K22278	ko00520,ko01100,map00520,map01100	M00664	R02333	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_C14,Polysacc_deac_1,TPR_16,TPR_8
GDHHQS2_k127_7105544_45	1286632.P278_02930	9.462e-30	125.0	COG0515@1|root,COG0515@2|Bacteria,4NIMA@976|Bacteroidetes,1I909@117743|Flavobacteriia	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08838,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko04131	-	-	-	MORN,Pkinase
GDHHQS2_k127_7105544_1	338966.Ppro_1453	4.938e-254	800.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
GDHHQS2_k127_7105544_55	525904.Tter_0346	3.285e-17	86.0	COG0762@1|root,COG0762@2|Bacteria,2NRP0@2323|unclassified Bacteria	2|Bacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
GDHHQS2_k127_7105544_53	926569.ANT_11150	1.161e-18	94.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi	200795|Chloroflexi	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS2_k127_7105544_59	1121106.JQKB01000059_gene4749	1.131e-14	84.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS2_k127_7105544_61	1235457.C404_25375	2.862e-12	76.0	2DRM2@1|root,33C8R@2|Bacteria,1NYP9@1224|Proteobacteria,2W33X@28216|Betaproteobacteria,1KC3W@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_12	525904.Tter_1614	1.045e-124	419.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
GDHHQS2_k127_7105544_62	981369.JQMJ01000004_gene713	9.672e-12	78.0	COG3405@1|root,COG4409@1|root,COG3405@2|Bacteria,COG4409@2|Bacteria,2ID1A@201174|Actinobacteria,2NGZY@228398|Streptacidiphilus	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7105544_67	1293048.CBMB010000010_gene3725	0.0001245	54.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02556@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria	183963|Halobacteria	S	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS2_k127_7105544_65	243232.MJ_0226	4.182e-09	65.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,23QP7@183939|Methanococci	183939|Methanococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS2_k127_7105544_64	1282361.ABAC402_14010	1.164e-09	63.0	COG0050@1|root,COG0050@2|Bacteria,1P5JQ@1224|Proteobacteria	1224|Proteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	-
GDHHQS2_k127_7105544_43	492774.JQMB01000007_gene3906	1.45e-33	137.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2TVFG@28211|Alphaproteobacteria,4B8IQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS2_k127_7105544_14	391009.Tmel_0560	1.12e-123	404.0	COG4608@1|root,COG4608@2|Bacteria,2GCGD@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_7105544_13	771875.Ferpe_1459	3.622e-124	406.0	COG0444@1|root,COG0444@2|Bacteria,2GCDR@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS2_k127_7105544_17	1150474.JQJI01000002_gene1198	5.303e-107	356.0	COG1173@1|root,COG1173@2|Bacteria,2GCK9@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_7105544_19	416591.Tlet_2007	1.48e-98	334.0	COG0601@1|root,COG0601@2|Bacteria,2GCPY@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS2_k127_7105544_16	1219084.AP014508_gene1040	2.144e-114	394.0	COG0747@1|root,COG0747@2|Bacteria,2GC1T@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
GDHHQS2_k127_7105544_26	1449337.JQLL01000001_gene1927	5.958e-75	263.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HBWI@91061|Bacilli	91061|Bacilli	E	Ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS2_k127_7105544_10	1499967.BAYZ01000065_gene6086	3.754e-130	425.0	COG3938@1|root,COG3938@2|Bacteria,2NQES@2323|unclassified Bacteria	2|Bacteria	E	Proline racemase	-	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
GDHHQS2_k127_7107182_0	357808.RoseRS_3659	4.604e-54	214.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS2_k127_7107182_2	1545915.JROG01000003_gene1309	1.326e-15	88.0	2C38E@1|root,33Z2K@2|Bacteria,1MY9G@1224|Proteobacteria,2U9BB@28211|Alphaproteobacteria,2K4JR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_7107182_1	479434.Sthe_2826	1.593e-47	184.0	COG3039@1|root,COG3039@2|Bacteria,2G8FF@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS2_k127_73814_1	926569.ANT_03770	7.929e-33	137.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GDHHQS2_k127_73814_0	926569.ANT_05730	3.633e-182	583.0	COG2233@1|root,COG2233@2|Bacteria,2G8VZ@200795|Chloroflexi	200795|Chloroflexi	F	Permease family	-	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
GDHHQS2_k127_919496_6	1499967.BAYZ01000090_gene4936	3.087e-60	223.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS2_k127_919496_31	545695.TREAZ_3104	1.144e-08	62.0	2ERYI@1|root,33JHP@2|Bacteria,2JAKC@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_919496_35	323261.Noc_2744	3.161e-05	49.0	2DS0K@1|root,33DZ7@2|Bacteria,1NKVW@1224|Proteobacteria,1SGDA@1236|Gammaproteobacteria,1X1VQ@135613|Chromatiales	135613|Chromatiales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS2_k127_919496_37	767817.Desgi_1671	0.0001077	50.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
GDHHQS2_k127_919496_26	1485543.JMME01000001_gene1356	9.45e-13	70.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,4H7Z0@909932|Negativicutes	909932|Negativicutes	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
GDHHQS2_k127_919496_29	886293.Sinac_0222	4.511e-11	70.0	COG2318@1|root,COG2318@2|Bacteria,2J1JI@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_919496_19	926550.CLDAP_05380	2.6e-30	126.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS2_k127_919496_33	867845.KI911784_gene2652	4.735e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_919496_27	326427.Cagg_2827	1.032e-12	81.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GDHHQS2_k127_919496_22	1121949.AQXT01000002_gene1652	3.317e-20	92.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UDKN@28211|Alphaproteobacteria,43YQK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS2_k127_919496_13	471853.Bcav_0186	4.961e-40	154.0	2CEIY@1|root,348HS@2|Bacteria,2H8Z7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS2_k127_919496_14	86416.Clopa_2107	4.176e-39	156.0	2CBE1@1|root,32RT5@2|Bacteria,1UPX9@1239|Firmicutes,25HR6@186801|Clostridia,36VC4@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_919496_12	1144312.PMI09_01640	1.275e-43	168.0	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2TUXA@28211|Alphaproteobacteria,4BNFX@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_919496_1	311424.DhcVS_1445	3.302e-102	343.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_919496_18	596152.DesU5LDRAFT_2493	2.128e-30	129.0	2DPHF@1|root,33237@2|Bacteria,1R4GY@1224|Proteobacteria,435JT@68525|delta/epsilon subdivisions,2WZY2@28221|Deltaproteobacteria,2M8FU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
GDHHQS2_k127_919496_5	1499967.BAYZ01000120_gene3420	4.996e-61	219.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_919496_24	1035308.AQYY01000001_gene2496	1.744e-13	83.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236,DUF560
GDHHQS2_k127_919496_0	1206731.BAGB01000076_gene6657	4.689e-105	350.0	COG3315@1|root,COG3315@2|Bacteria,2GN89@201174|Actinobacteria,4G3VX@85025|Nocardiaceae	201174|Actinobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
GDHHQS2_k127_919496_3	485913.Krac_7152	1.538e-70	246.0	COG2020@1|root,COG2020@2|Bacteria,2G9T5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS2_k127_919496_7	868131.MSWAN_2217	1.275e-55	204.0	COG0596@1|root,arCOG01648@2157|Archaea,2XVXV@28890|Euryarchaeota,23PSC@183925|Methanobacteria	183925|Methanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS2_k127_919496_10	1265310.CCBD010000007_gene3204	2.259e-45	174.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS2_k127_919496_11	1265310.CCBD010000007_gene3204	6.421e-45	173.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS2_k127_919496_15	879212.DespoDRAFT_00979	3.547e-35	137.0	2CCSR@1|root,32K43@2|Bacteria,1QJ8W@1224|Proteobacteria,43A9D@68525|delta/epsilon subdivisions,2X0VC@28221|Deltaproteobacteria,2MPDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_919496_32	264732.Moth_1271	4.161e-07	60.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,24S59@186801|Clostridia,42J2N@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS2_k127_919496_34	1122223.KB890700_gene2003	7.266e-07	57.0	COG1543@1|root,COG1543@2|Bacteria,1WIRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	hydrolase family 57	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
GDHHQS2_k127_919496_16	497965.Cyan7822_3223	9.395e-34	134.0	COG4113@1|root,COG4113@2|Bacteria,1G6PI@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG4113 nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS2_k127_919496_17	717606.PaecuDRAFT_4203	2.783e-33	138.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HXCZ@91061|Bacilli,274IH@186822|Paenibacillaceae	91061|Bacilli	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS2_k127_919496_8	521098.Aaci_1325	2.433e-52	208.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS2_k127_919496_21	1229487.AMYW01000007_gene3291	2.966e-26	111.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I2SV@117743|Flavobacteriia,2P0MB@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS2_k127_919496_9	309801.trd_0544	1.342e-48	187.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS2_k127_919496_30	944479.JQLX01000010_gene565	1.701e-09	69.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2M6AS@213113|Desulfurellales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS2_k127_919496_2	316274.Haur_1259	5.405e-96	323.0	COG2267@1|root,COG2267@2|Bacteria,2GAKU@200795|Chloroflexi,376PC@32061|Chloroflexia	32061|Chloroflexia	T	Pfam:DUF2305	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS2_k127_919496_36	926550.CLDAP_11920	7.138e-05	56.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
GDHHQS2_k127_919496_20	926550.CLDAP_11940	7.966e-29	134.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS2_k127_919496_28	1521187.JPIM01000002_gene3208	2.921e-12	78.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi,376Y5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS2_k127_919496_25	1458357.BG58_06805	2.046e-13	83.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria,1KDJD@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS2_k127_919496_4	926569.ANT_28000	2.028e-63	235.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
GDHHQS2_k127_919496_23	745718.JADT01000018_gene648	3.367e-18	98.0	COG0507@1|root,COG0507@2|Bacteria,4NICX@976|Bacteroidetes,1I2E9@117743|Flavobacteriia	976|Bacteroidetes	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
GDHHQS2_k127_93627_25	1341679.P253_00066	4.487e-05	45.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,3NKN1@468|Moraxellaceae	1236|Gammaproteobacteria	L	Evidence 1 Function experimentally demonstrated in the studied organism	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
GDHHQS2_k127_93627_4	378806.STAUR_3675	7.161e-86	289.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,42QZ4@68525|delta/epsilon subdivisions,2WUIV@28221|Deltaproteobacteria,2YUFC@29|Myxococcales	28221|Deltaproteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
GDHHQS2_k127_93627_0	1128421.JAGA01000003_gene3066	2.204e-248	814.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS2_k127_93627_17	1227500.C494_14046	2.01e-24	112.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS2_k127_93627_22	1122609.AUGT01000002_gene3814	5.153e-13	83.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GDHHQS2_k127_93627_8	926569.ANT_31760	2.122e-60	223.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
GDHHQS2_k127_93627_5	1499967.BAYZ01000009_gene5348	5.444e-82	278.0	COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS2_k127_93627_18	357808.RoseRS_1405	1.242e-23	108.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS2_k127_93627_7	1463856.JOHY01000004_gene6507	1.384e-67	233.0	COG2606@1|root,COG2606@2|Bacteria,2IMZE@201174|Actinobacteria	201174|Actinobacteria	G	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS2_k127_93627_1	760192.Halhy_4463	3.139e-151	490.0	COG2072@1|root,COG2072@2|Bacteria,4NGC0@976|Bacteroidetes,1ITWD@117747|Sphingobacteriia	976|Bacteroidetes	P	flavoprotein involved in K transport	-	-	1.14.13.148	ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like
GDHHQS2_k127_93627_23	1123261.AXDW01000002_gene1553	1.982e-11	75.0	COG0443@1|root,COG0443@2|Bacteria,1P7BK@1224|Proteobacteria,1RRN2@1236|Gammaproteobacteria,1X4Q7@135614|Xanthomonadales	135614|Xanthomonadales	O	PRTRC system protein D	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_93627_10	1242864.D187_002408	3.94e-41	164.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS2_k127_93627_2	926569.ANT_23310	1.115e-111	369.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS2_k127_93627_13	391603.FBALC1_14667	4.207e-33	133.0	COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia	976|Bacteroidetes	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS2_k127_93627_15	1192034.CAP_5968	3.291e-28	119.0	COG4430@1|root,COG4430@2|Bacteria,1QZAG@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
GDHHQS2_k127_93627_14	926550.CLDAP_35470	3.394e-29	132.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
GDHHQS2_k127_93627_9	1150864.MILUP08_41371	4.396e-42	166.0	COG0457@1|root,COG0457@2|Bacteria,2IETK@201174|Actinobacteria,4DC2D@85008|Micromonosporales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
GDHHQS2_k127_93627_11	926560.KE387027_gene603	9.563e-40	156.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS2_k127_93627_12	111781.Lepto7376_3781	4.412e-35	138.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HC2V@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GDHHQS2_k127_93627_24	1267535.KB906767_gene1792	1.26e-06	54.0	2E14U@1|root,33IVM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_93627_19	56780.SYN_00188	8.926e-21	104.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MQDX@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS2_k127_93627_16	1121354.AQUV01000001_gene1332	1.595e-24	121.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
GDHHQS2_k127_93627_27	316274.Haur_3616	0.0001494	55.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria,2G8N3@200795|Chloroflexi,3757D@32061|Chloroflexia	32061|Chloroflexia	MT	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_93627_6	926569.ANT_26810	1.387e-77	272.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
GDHHQS2_k127_93627_21	485913.Krac_3903	5.981e-14	78.0	2EACU@1|root,334GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS2_k127_93627_3	926569.ANT_05570	1.339e-101	344.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS2_k127_975707_0	926569.ANT_03860	2.397e-192	610.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS2_k127_975707_23	638302.HMPREF0908_1787	2.805e-24	116.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4H4XS@909932|Negativicutes	909932|Negativicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
GDHHQS2_k127_975707_17	926569.ANT_03840	2.207e-36	145.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS2_k127_975707_20	926550.CLDAP_31840	1.33e-33	141.0	COG0491@1|root,COG0491@2|Bacteria,2G93C@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_975707_7	1499967.BAYZ01000103_gene3745	4.327e-84	294.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS2_k127_975707_15	926569.ANT_00400	2.619e-40	163.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_4	926569.ANT_00390	6.072e-111	380.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
GDHHQS2_k127_975707_18	926569.ANT_00380	3.759e-34	141.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_24	926569.ANT_00360	1.217e-19	96.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_21	926569.ANT_00350	1.118e-32	136.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_12	861299.J421_2552	4.924e-51	190.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS2_k127_975707_16	926550.CLDAP_29140	1.31e-37	146.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS2_k127_975707_11	926569.ANT_16740	3.358e-62	227.0	COG1226@1|root,COG1226@2|Bacteria,2G7EI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
GDHHQS2_k127_975707_25	676032.FN3523_0779	3.226e-09	62.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS2_k127_975707_27	1114959.SZMC14600_18194	0.0003254	54.0	COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_14	246197.MXAN_4966	5.563e-45	173.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
GDHHQS2_k127_975707_13	926550.CLDAP_04460	8.15e-47	193.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975707_8	357808.RoseRS_4524	1.22e-83	289.0	COG0472@1|root,COG0472@2|Bacteria,2G7WQ@200795|Chloroflexi,375BA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS2_k127_975707_26	1279009.ADICEAN_03753	0.0003218	53.0	COG3507@1|root,COG3507@2|Bacteria,4NJ7K@976|Bacteroidetes,47KDE@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
GDHHQS2_k127_975707_1	926550.CLDAP_19310	3.332e-161	517.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
GDHHQS2_k127_975707_3	1172179.AUKV01000001_gene1316	5.453e-130	423.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
GDHHQS2_k127_975707_5	1500306.JQLA01000010_gene755	3.101e-102	342.0	COG1176@1|root,COG1176@2|Bacteria,1NU6V@1224|Proteobacteria,2TU7Q@28211|Alphaproteobacteria,4B8W5@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	spermidine putrescine	ydcU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS2_k127_975707_6	395961.Cyan7425_3619	1.067e-89	303.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,3KIJX@43988|Cyanothece	1117|Cyanobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
GDHHQS2_k127_975707_9	926550.CLDAP_19020	3.488e-70	247.0	COG0491@1|root,COG0491@2|Bacteria,2G9AW@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS2_k127_975707_10	383372.Rcas_2015	2.261e-69	247.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS2_k127_975707_2	926569.ANT_09890	6.414e-142	492.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS2_k127_975707_22	383372.Rcas_3938	1.534e-24	119.0	COG3664@1|root,COG3664@2|Bacteria,2GBKZ@200795|Chloroflexi,37642@32061|Chloroflexia	32061|Chloroflexia	G	Flagellar filament outer layer protein Flaa	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
GDHHQS2_k127_975786_0	926569.ANT_22850	0.0	1325.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS2_k127_975786_4	1123487.KB892865_gene1455	0.0003379	51.0	COG2214@1|root,COG2214@2|Bacteria,1ND5S@1224|Proteobacteria	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS2_k127_975786_1	536227.CcarbDRAFT_4777	1.756e-98	326.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
GDHHQS2_k127_975786_2	1123355.JHYO01000022_gene25	7.798e-43	169.0	COG3551@1|root,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,TPR_19
GDHHQS2_k127_975786_3	649747.HMPREF0083_01528	8.931e-07	52.0	COG0596@1|root,COG0596@2|Bacteria,1VEDI@1239|Firmicutes,4HQQ2@91061|Bacilli,26VR3@186822|Paenibacillaceae	91061|Bacilli	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
## 3723 queries scanned
## Total time (seconds): 379.3011908531189
## Rate: 9.82 q/s