## Sat Nov 16 09:56:03 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin3/GDHHQS_3_bin.35.fa -m mmseqs --itype genome -o GDHHQS_3_bin.35 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/GDHHQS_3_bin.35 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS3_k127_1030309_1	861299.J421_2796	7.171e-118	383.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_1030309_2	379066.GAU_0894	4.869e-80	273.0	COG0563@1|root,COG0563@2|Bacteria,1ZTHC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
GDHHQS3_k127_1030309_0	861299.J421_2794	4.537e-217	680.0	COG0201@1|root,COG0201@2|Bacteria,1ZSYZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS3_k127_1030309_3	379066.GAU_0892	6.335e-12	66.0	COG0200@1|root,COG0200@2|Bacteria,1ZTP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GDHHQS3_k127_1031059_0	316067.Geob_3322	5.391e-236	740.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.109.1,3.A.1.109.2,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
GDHHQS3_k127_1031059_1	522306.CAP2UW1_1495	8.045e-118	414.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
GDHHQS3_k127_106559_0	1379270.AUXF01000005_gene693	5.662e-179	571.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS3_k127_106559_2	861299.J421_3078	1.398e-59	216.0	COG1589@1|root,COG1589@2|Bacteria,1ZTRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
GDHHQS3_k127_106559_1	861299.J421_3077	8.668e-72	246.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_106804_2	861299.J421_1941	2.767e-80	273.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_106804_4	861299.J421_1942	3.915e-44	171.0	COG1937@1|root,COG1937@2|Bacteria,1ZTZF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS3_k127_106804_5	379066.GAU_0242	1.214e-38	153.0	2F4AY@1|root,33YV0@2|Bacteria,1ZU13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_106804_6	1379270.AUXF01000001_gene2214	6.792e-22	97.0	2F75B@1|root,33ZKU@2|Bacteria,1ZTZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_106804_1	1210884.HG799466_gene13015	4.895e-102	340.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS3_k127_106804_3	754035.Mesau_04046	5.331e-53	194.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,43JN0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS3_k127_106804_0	861299.J421_3797	1.497e-109	364.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS3_k127_106804_7	243090.RB4394	9.006e-19	88.0	COG0693@1|root,COG0693@2|Bacteria,2IYUH@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease amidase	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS3_k127_1102678_4	861299.J421_2531	6.327e-32	129.0	COG3584@1|root,COG3584@2|Bacteria	2|Bacteria	T	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3,SLH
GDHHQS3_k127_1102678_1	379066.GAU_0602	1.226e-151	483.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_1102678_3	861299.J421_2345	2.059e-60	221.0	COG1597@1|root,COG1597@2|Bacteria,1ZVAI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS3_k127_1102678_0	861299.J421_2525	6.795e-205	648.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_1102678_2	861299.J421_2524	3.494e-84	292.0	COG0277@1|root,COG0277@2|Bacteria,1ZTRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
GDHHQS3_k127_111347_2	861299.J421_2316	3.489e-152	489.0	COG4603@1|root,COG4603@2|Bacteria,1ZTDA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_111347_4	519441.Smon_0504	6.548e-143	471.0	COG3845@1|root,COG3845@2|Bacteria,378EE@32066|Fusobacteria	32066|Fusobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS3_k127_111347_3	861299.J421_2318	1.609e-151	507.0	COG1744@1|root,COG1744@2|Bacteria,1ZTAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS3_k127_111347_0	861299.J421_2321	5.011e-238	744.0	COG0029@1|root,COG0029@2|Bacteria,1ZT8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_111347_1	1379270.AUXF01000002_gene1768	1.836e-161	514.0	COG0379@1|root,COG0379@2|Bacteria,1ZT10@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS3_k127_111347_5	861299.J421_2323	5.019e-113	373.0	COG0157@1|root,COG0157@2|Bacteria,1ZSR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GDHHQS3_k127_1129918_0	509190.Cseg_0853	1.48e-212	674.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2KF25@204458|Caulobacterales	204458|Caulobacterales	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_1129918_1	994479.GL877880_gene4123	3.642e-50	186.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria,4EFE8@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_1134587_0	926566.Terro_2899	3.563e-182	581.0	COG2303@1|root,COG2303@2|Bacteria,3Y6FS@57723|Acidobacteria,2JM7Q@204432|Acidobacteriia	204432|Acidobacteriia	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1137793_0	279714.FuraDRAFT_0324	2.288e-45	168.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KQ3F@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
GDHHQS3_k127_1137793_2	1379270.AUXF01000002_gene1393	3.298e-29	124.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS3_k127_1137793_1	204669.Acid345_4011	1.447e-36	145.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1137793_3	237727.NAP1_11743	3.535e-26	111.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,2KD9Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
GDHHQS3_k127_1137793_4	861299.J421_5889	9.011e-18	85.0	2DSP1@1|root,33GVU@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
GDHHQS3_k127_1138689_7	472759.Nhal_3969	1.886e-20	103.0	2E953@1|root,333DW@2|Bacteria,1NMYM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1138689_4	1162668.LFE_0136	8.991e-30	129.0	COG3636@1|root,COG3636@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1138689_3	1173029.JH980292_gene2839	5.404e-33	138.0	COG3657@1|root,COG3657@2|Bacteria,1G6YT@1117|Cyanobacteria,1HCJV@1150|Oscillatoriales	1117|Cyanobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS3_k127_1138689_9	1247963.JPHU01000002_gene2720	1.319e-07	53.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_1138689_2	1116472.MGMO_131c00060	6.421e-38	143.0	COG5606@1|root,COG5606@2|Bacteria,1PQ56@1224|Proteobacteria,1RVP6@1236|Gammaproteobacteria,1XGUG@135618|Methylococcales	135618|Methylococcales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
GDHHQS3_k127_1138689_1	637390.AFOH01000025_gene1036	5.902e-42	162.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
GDHHQS3_k127_1138689_6	1382303.JPOM01000001_gene1510	1.202e-26	117.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KFFQ@204458|Caulobacterales	204458|Caulobacterales	E	peptidase S9A prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_1138689_0	765912.Thimo_3412	1.223e-46	171.0	COG5573@1|root,COG5573@2|Bacteria,1RKIK@1224|Proteobacteria,1SBYM@1236|Gammaproteobacteria,1WZ8S@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_1138689_8	261292.Nit79A3_0971	3.433e-17	86.0	2E8K6@1|root,332XV@2|Bacteria,1NE25@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1138689_5	234267.Acid_4226	1.006e-27	115.0	COG3636@1|root,COG3636@2|Bacteria,3Y5IY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1181052_2	1122137.AQXF01000001_gene3111	8.105e-24	117.0	COG2271@1|root,COG2271@2|Bacteria,1QV8S@1224|Proteobacteria,2TZ56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_1181052_3	867903.ThesuDRAFT_02369	3.768e-07	63.0	29Y0M@1|root,30JTI@2|Bacteria,1VEVD@1239|Firmicutes,24QVV@186801|Clostridia,3WDJ2@538999|Clostridiales incertae sedis	186801|Clostridia	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
GDHHQS3_k127_1181052_0	644966.Tmar_0199	2.398e-67	247.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,3WDRY@538999|Clostridiales incertae sedis	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
GDHHQS3_k127_1181052_1	479434.Sthe_0949	2.77e-25	106.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GDHHQS3_k127_1181463_5	1454007.JAUG01000094_gene175	1.638e-10	68.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,1IVKP@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
GDHHQS3_k127_1181463_2	861299.J421_5840	3.278e-235	767.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_1181463_4	861299.J421_2630	3.147e-26	113.0	COG0355@1|root,COG0355@2|Bacteria,1ZU1K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
GDHHQS3_k127_1181463_1	861299.J421_2629	2.729e-249	799.0	COG0055@1|root,COG0055@2|Bacteria,1ZSNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS3_k127_1181463_3	861299.J421_2628	1.083e-124	404.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GDHHQS3_k127_1181463_0	861299.J421_2627	8.511e-283	874.0	COG0056@1|root,COG0056@2|Bacteria,1ZSNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS3_k127_1185001_1	861299.J421_1951	3.899e-58	213.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_1185001_0	1304880.JAGB01000001_gene67	3.776e-123	415.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_1185718_2	861299.J421_2643	1.633e-63	226.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GDHHQS3_k127_1185718_4	861299.J421_2642	1.934e-57	207.0	COG1651@1|root,COG1651@2|Bacteria,1ZTVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS3_k127_1185718_0	861299.J421_2641	9.104e-133	437.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
GDHHQS3_k127_1185718_3	861299.J421_2640	2.414e-58	220.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
GDHHQS3_k127_1185718_1	861299.J421_2639	2.248e-85	299.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	2.6.1.85	ko:K13950,ko:K21025	ko00790,ko02025,map00790,map02025	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
GDHHQS3_k127_1185718_5	861299.J421_2638	1.485e-52	188.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2638|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1185718_6	861299.J421_1672	1.337e-07	59.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_1190341_1	1379270.AUXF01000003_gene3745	2.416e-28	123.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_1190341_0	1267534.KB906761_gene1211	1.985e-56	216.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria,2JMQC@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_1193183_1	861299.J421_1204	6.838e-135	434.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_1193183_0	861299.J421_1205	1.455e-169	557.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD3	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
GDHHQS3_k127_1193183_3	1146883.BLASA_1918	2.855e-38	150.0	COG2905@1|root,COG2905@2|Bacteria,2I5MP@201174|Actinobacteria,4EXD4@85013|Frankiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_1193183_2	1210884.HG799464_gene10502	8.499e-72	264.0	COG0515@1|root,COG2203@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS3_k127_1194611_4	319225.Plut_0012	2.728e-77	271.0	COG1530@1|root,COG1530@2|Bacteria,1FDIW@1090|Chlorobi	1090|Chlorobi	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
GDHHQS3_k127_1194611_5	861299.J421_3339	4.64e-57	205.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_1194611_2	861299.J421_3340	3.654e-203	638.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_1194611_1	517418.Ctha_1907	5.516e-262	837.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_1194611_0	861299.J421_3341	5.397e-275	861.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
GDHHQS3_k127_1194611_3	661478.OP10G_0723	8.937e-96	322.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1194611_7	1267534.KB906755_gene4755	1.052e-46	181.0	COG1024@1|root,COG1024@2|Bacteria,3Y3SE@57723|Acidobacteria,2JIII@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_1194611_6	861299.J421_3344	3.919e-54	192.0	2CIU6@1|root,32S8H@2|Bacteria,1ZTUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1201564_11	861299.J421_4532	4.629e-12	68.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1201564_6	861299.J421_4533	3.982e-140	453.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS3_k127_1201564_3	861299.J421_4536	1.289e-166	541.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS3_k127_1201564_0	379066.GAU_2856	4.371e-266	842.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GDHHQS3_k127_1201564_1	379066.GAU_2857	1.494e-204	643.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_1201564_8	861299.J421_1546	1.08e-118	394.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1ZTKM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18
GDHHQS3_k127_1201564_10	1267534.KB906756_gene299	4.268e-42	163.0	29PQU@1|root,30AP1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
GDHHQS3_k127_1201564_5	483219.LILAB_09765	1.195e-152	498.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GDHHQS3_k127_1201564_9	861299.J421_0057	1.202e-65	228.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_1201564_4	251221.35211608	1.148e-163	527.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS3_k127_1201564_7	861299.J421_0058	1.284e-136	443.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_1201564_2	861299.J421_0060	4.269e-174	563.0	COG1524@1|root,COG1524@2|Bacteria,1ZT33@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_1201564_13	1382306.JNIM01000001_gene1291	5.374e-07	55.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368,ko:K02638	ko00195,ko00910,ko01120,map00195,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CHRD,Copper-bind,Cu-oxidase_3,Cupredoxin_1
GDHHQS3_k127_1202057_1	861299.J421_5759	2.139e-141	477.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_1202057_3	861299.J421_3986	7.541e-12	71.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
GDHHQS3_k127_1202057_0	379066.GAU_2144	1.009e-313	969.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_1202057_2	1489678.RDMS_12985	2.858e-75	265.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
GDHHQS3_k127_1202057_4	675635.Psed_3166	6.868e-07	51.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,4DZW2@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	ytfL	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
GDHHQS3_k127_1216659_0	861299.J421_0240	0.0	1097.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_1216659_1	861299.J421_0690	1.787e-26	110.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_1226547_2	1267534.KB906755_gene4573	2.298e-26	114.0	COG0842@1|root,COG0842@2|Bacteria,3Y6GQ@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_1226547_0	234267.Acid_6967	4.487e-128	415.0	COG1131@1|root,COG1131@2|Bacteria,3Y78D@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1226547_1	1121423.JONT01000014_gene1270	1.175e-40	159.0	COG0702@1|root,COG0702@2|Bacteria,1UNU6@1239|Firmicutes	1239|Firmicutes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1228736_1	861299.J421_1357	1.825e-106	346.0	COG2159@1|root,COG2159@2|Bacteria,1ZSR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_1228736_2	404589.Anae109_4237	4.924e-40	156.0	2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1228736_0	1043205.AFYF01000087_gene1181	1.085e-143	471.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4FFAM@85021|Intrasporangiaceae	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
GDHHQS3_k127_1243746_4	861299.J421_3835	5.71e-98	329.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_1243746_1	861299.J421_3836	3.77e-130	426.0	COG1816@1|root,COG1816@2|Bacteria,1ZSQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS3_k127_1243746_5	1379270.AUXF01000003_gene3571	3.64e-11	67.0	290N8@1|root,2ZNAK@2|Bacteria,1ZU7A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1243746_0	379066.GAU_2357	2.567e-293	933.0	COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
GDHHQS3_k127_1243746_3	379066.GAU_2359	6.465e-101	337.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1243746_2	379066.GAU_2360	1.823e-117	399.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_1246280_3	861299.J421_2383	7.458e-38	143.0	COG1249@1|root,COG1249@2|Bacteria,1ZTF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_1246280_0	379066.GAU_0480	1.099e-165	530.0	COG0508@1|root,COG0508@2|Bacteria,1ZTB5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_1246280_1	861299.J421_2390	3.643e-148	476.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_1246280_4	861299.J421_2391	5.293e-21	97.0	28TV6@1|root,2ZG24@2|Bacteria,1ZV98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1246280_2	379066.GAU_1264	6.052e-53	206.0	2AEWW@1|root,314UI@2|Bacteria,1ZUPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1260527_4	498848.TaqDRAFT_3912	9.617e-66	228.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS3_k127_1260527_0	760192.Halhy_6459	2.305e-103	354.0	COG1680@1|root,COG1680@2|Bacteria,4PP29@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
GDHHQS3_k127_1260527_3	316067.Geob_3393	2.145e-79	272.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS3_k127_1260527_5	234267.Acid_4549	4.376e-58	213.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1260527_1	1340493.JNIF01000003_gene3871	7.885e-99	342.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_1260527_2	1379270.AUXF01000002_gene1817	1.875e-97	326.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GDHHQS3_k127_1265574_1	379066.GAU_1484	6.539e-183	581.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS3_k127_1265574_0	861299.J421_3127	1.903e-253	795.0	COG1080@1|root,COG1080@2|Bacteria,1ZT3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS3_k127_1265574_2	1379270.AUXF01000005_gene735	7.003e-28	117.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_1265574_3	861299.J421_3125	1.402e-08	57.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
GDHHQS3_k127_1279662_6	861299.J421_3057	1.068e-95	339.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS3_k127_1279662_16	1379270.AUXF01000005_gene669	3.728e-47	178.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
GDHHQS3_k127_1279662_3	1379270.AUXF01000005_gene668	9.7e-123	411.0	COG0643@1|root,COG0643@2|Bacteria,1ZT7R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	P2 response regulator binding domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
GDHHQS3_k127_1279662_12	1379270.AUXF01000005_gene667	1.348e-56	199.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GDHHQS3_k127_1279662_17	592015.HMPREF1705_00008	6.35e-16	85.0	COG0835@1|root,COG0835@2|Bacteria,3TBA6@508458|Synergistetes	508458|Synergistetes	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GDHHQS3_k127_1279662_2	861299.J421_3052	1.728e-134	437.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_1279662_14	1379270.AUXF01000005_gene663	3.986e-52	193.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS3_k127_1279662_10	861299.J421_3049	1.089e-67	232.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
GDHHQS3_k127_1279662_0	861299.J421_3048	0.0	1384.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS3_k127_1279662_13	379066.GAU_1397	1.148e-55	199.0	COG3599@1|root,COG3599@2|Bacteria,1ZUSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
GDHHQS3_k127_1279662_7	861299.J421_3047	1.007e-89	300.0	COG0325@1|root,COG3599@1|root,COG0325@2|Bacteria,COG3599@2|Bacteria,1ZTJZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS3_k127_1279662_18	710111.FraQA3DRAFT_2664	8.789e-14	79.0	COG4758@1|root,COG4758@2|Bacteria,2HP3D@201174|Actinobacteria,4EX1Q@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
GDHHQS3_k127_1279662_8	379066.GAU_1769	7.417e-87	302.0	COG0750@1|root,COG0750@2|Bacteria,1ZSKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,Peptidase_M50
GDHHQS3_k127_1279662_1	861299.J421_3406	7.026e-171	545.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS3_k127_1279662_5	861299.J421_3407	7.099e-103	341.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS3_k127_1279662_9	861299.J421_3409	9.427e-71	243.0	COG0233@1|root,COG0233@2|Bacteria,1ZTI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS3_k127_1279662_4	1379270.AUXF01000006_gene121	1.574e-108	355.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_1279662_11	1125863.JAFN01000001_gene969	3.7e-65	229.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS3_k127_1279662_15	379066.GAU_1776	2.319e-49	179.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS3_k127_1289148_2	1379270.AUXF01000006_gene216	1.673e-34	138.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS3_k127_1289148_3	379066.GAU_1676	1.763e-31	127.0	COG1314@1|root,COG1314@2|Bacteria,1ZTZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS3_k127_1289148_1	861299.J421_3308	2.312e-80	287.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS3_k127_1289148_0	1379270.AUXF01000006_gene213	2.008e-128	415.0	COG0126@1|root,COG0126@2|Bacteria,1ZT1B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS3_k127_1303404_3	393921.HQ45_08665	2.957e-13	74.0	COG1585@1|root,COG1585@2|Bacteria,4NY97@976|Bacteroidetes,2FYNR@200643|Bacteroidia	976|Bacteroidetes	OU	Nodulation efficiency protein	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
GDHHQS3_k127_1303404_1	880073.Calab_3078	2.323e-124	406.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_1303404_2	215803.DB30_3931	2.346e-38	151.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
GDHHQS3_k127_1303404_0	880073.Calab_0069	7.712e-140	452.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_1318986_3	619693.HMPREF6745_3050	5.25e-12	70.0	COG1585@1|root,COG1585@2|Bacteria,4NY97@976|Bacteroidetes,2FYNR@200643|Bacteroidia	976|Bacteroidetes	OU	Nodulation efficiency protein	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
GDHHQS3_k127_1318986_1	880073.Calab_3078	7.39e-123	402.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_1318986_2	797210.Halxa_1281	2.834e-26	123.0	COG1719@1|root,arCOG01688@2157|Archaea,2Y381@28890|Euryarchaeota,23Z5Y@183963|Halobacteria	183963|Halobacteria	S	Heme NO binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
GDHHQS3_k127_1318986_0	880073.Calab_0069	1.193e-129	424.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_1343495_0	1163617.SCD_n00704	0.0	1268.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
GDHHQS3_k127_1343495_3	2002.JOEQ01000022_gene6872	2.017e-25	106.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4EGQW@85012|Streptosporangiales	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_1343495_2	861299.J421_6306	5.715e-31	126.0	COG1734@1|root,COG1734@2|Bacteria,1ZV6D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1343495_4	497964.CfE428DRAFT_2476	9.766e-12	72.0	2C5W2@1|root,33IGR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1343495_1	886293.Sinac_3761	1.052e-64	236.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_1347200_5	886293.Sinac_4724	3.308e-33	134.0	COG2340@1|root,COG2340@2|Bacteria,2J0UH@203682|Planctomycetes	203682|Planctomycetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GDHHQS3_k127_1347200_2	861299.J421_3775	2.918e-172	552.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
GDHHQS3_k127_1347200_1	379066.GAU_2166	5.082e-276	856.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
GDHHQS3_k127_1347200_0	861299.J421_3771	0.0	1183.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1ZT01@142182|Gemmatimonadetes	2|Bacteria	C	Phosphate acetyl/butaryl transferase	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
GDHHQS3_k127_1347200_3	247490.KSU1_D0782	5.592e-119	398.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1347200_4	247490.KSU1_D0783	1.457e-86	295.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
GDHHQS3_k127_1348999_9	379066.GAU_1556	4.658e-24	102.0	COG0532@1|root,COG0532@2|Bacteria,1ZT5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GDHHQS3_k127_1348999_8	861299.J421_3187	1.443e-26	112.0	COG1358@1|root,COG1358@2|Bacteria,1ZU1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
GDHHQS3_k127_1348999_0	1379270.AUXF01000005_gene820	5.118e-217	684.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
GDHHQS3_k127_1348999_7	1379270.AUXF01000005_gene819	1.184e-41	158.0	COG0779@1|root,COG0779@2|Bacteria,1ZTX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
GDHHQS3_k127_1348999_4	861299.J421_5728	3.653e-122	416.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS3_k127_1348999_6	861299.J421_3184	1.383e-82	281.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS3_k127_1348999_1	114615.BRADO0005	9.327e-209	657.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,3JVEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS3_k127_1348999_10	1379270.AUXF01000005_gene816	2.934e-14	81.0	2A100@1|root,30P5D@2|Bacteria,1ZUX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1348999_3	861299.J421_3181	1.961e-129	421.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
GDHHQS3_k127_1348999_2	861299.J421_3180	1.938e-191	619.0	COG0064@1|root,COG0064@2|Bacteria,1ZTCB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS3_k127_1348999_5	198467.NP92_00120	4.11e-89	303.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,21V76@150247|Anoxybacillus	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS3_k127_1358353_1	1382356.JQMP01000004_gene107	3.759e-67	244.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
GDHHQS3_k127_1358353_2	529709.PYCH_12070	8.951e-37	146.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_1358353_0	861299.J421_4169	4.294e-73	263.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_1358353_4	1232410.KI421421_gene3795	1.241e-18	98.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2WPS7@28221|Deltaproteobacteria,43V71@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_5
GDHHQS3_k127_1358353_3	861299.J421_4436	3.367e-31	129.0	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GDHHQS3_k127_1386208_6	861299.J421_4541	4.43e-28	117.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_1386208_7	330214.NIDE1608	1.38e-18	94.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
GDHHQS3_k127_1386208_3	861299.J421_4538	1.094e-37	156.0	2C9AW@1|root,2ZVNX@2|Bacteria,1ZUAK@142182|Gemmatimonadetes	861299.J421_4538|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1386208_11	861299.J421_1305	7.72e-10	69.0	28YSJ@1|root,343H2@2|Bacteria,1ZU2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1386208_10	861299.J421_1152	4.43e-16	87.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_1386208_0	1192124.LIG30_4270	1.305e-50	192.0	COG0332@1|root,COG0332@2|Bacteria,1RARU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM 3-oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS3_k127_1386208_5	877455.Metbo_0278	2.5e-29	134.0	COG0451@1|root,COG1022@1|root,arCOG01369@2157|Archaea,arCOG04199@2157|Archaea,2XT0U@28890|Euryarchaeota	28890|Euryarchaeota	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_1386208_2	1121946.AUAX01000002_gene93	4.317e-40	162.0	COG0172@1|root,COG0172@2|Bacteria,2GKVE@201174|Actinobacteria,4DFWQ@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2b
GDHHQS3_k127_1386208_13	420662.Mpe_B0247	2.103e-05	55.0	COG1633@1|root,COG1633@2|Bacteria,1MXX8@1224|Proteobacteria,2VI3H@28216|Betaproteobacteria,1KJG3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1386208_12	118163.Ple7327_1235	3.456e-08	64.0	COG2833@1|root,COG2833@2|Bacteria,1GQKS@1117|Cyanobacteria,3VIR2@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
GDHHQS3_k127_1386208_1	1123252.ATZF01000003_gene3596	2.298e-40	166.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
GDHHQS3_k127_1386208_9	1124991.MU9_2789	3.206e-16	93.0	2BZ6D@1|root,2ZC6J@2|Bacteria,1RBC8@1224|Proteobacteria,1S3G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1386208_8	1267534.KB906759_gene1822	1.292e-16	88.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	mmpL3	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264	-	ko:K06994,ko:K07003,ko:K20466,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.5,2.A.6.5.6	-	-	MMPL
GDHHQS3_k127_1391053_3	861299.J421_5981	1.182e-68	249.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5981|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1391053_2	379066.GAU_1999	8.311e-146	475.0	COG3876@1|root,COG3876@2|Bacteria,1ZUBN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
GDHHQS3_k127_1391053_0	251221.35214024	7.347e-208	663.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS3_k127_1391053_4	861299.J421_3606	1.878e-56	198.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
GDHHQS3_k127_1391053_1	1379270.AUXF01000003_gene3853	3.029e-190	602.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GDHHQS3_k127_1400724_0	861299.J421_2847	0.0	1326.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
GDHHQS3_k127_1400724_7	1128421.JAGA01000001_gene2028	2.709e-25	113.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
GDHHQS3_k127_1400724_6	379066.GAU_1343	1.366e-31	133.0	COG0457@1|root,COG0457@2|Bacteria,1ZUVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS3_k127_1400724_5	404589.Anae109_1512	2.335e-50	186.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1400724_3	861299.J421_2867	4.112e-163	521.0	COG0176@1|root,COG0176@2|Bacteria,1ZSZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS3_k127_1400724_2	379066.GAU_1104	9.361e-184	592.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS3_k127_1400724_4	1379270.AUXF01000005_gene378	5.193e-102	340.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
GDHHQS3_k127_1400724_1	861299.J421_2873	7.398e-184	585.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS3_k127_142446_0	861299.J421_1775	2.717e-109	375.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_142446_1	861299.J421_1776	5.578e-104	353.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_142446_2	861299.J421_1777	3.09e-67	234.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1444450_1	861299.J421_2344	8.108e-77	262.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_1444450_0	1379270.AUXF01000002_gene1787	5.382e-112	374.0	COG0726@1|root,COG0726@2|Bacteria,1ZSTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS3_k127_1444450_2	861299.J421_2341	1.735e-33	130.0	2F2MH@1|root,33VI3@2|Bacteria,1ZTMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1446955_0	869210.Marky_1927	1.06e-174	563.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS3_k127_1446955_1	861299.J421_6216	1.167e-07	60.0	COG1629@1|root,COG4771@2|Bacteria,1ZTA1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_149636_2	861299.J421_3936	8.382e-91	301.0	COG1409@1|root,COG1409@2|Bacteria,1ZTQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_149636_3	861299.J421_3935	2.844e-63	224.0	2C421@1|root,33VAH@2|Bacteria,1ZTQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
GDHHQS3_k127_149636_1	861299.J421_3934	1.422e-208	654.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_149636_4	1207076.ALAT01000225_gene700	3.094e-17	90.0	COG0467@1|root,COG0467@2|Bacteria,1RK1W@1224|Proteobacteria,1T9X6@1236|Gammaproteobacteria,1Z3R0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS
GDHHQS3_k127_149636_0	861299.J421_0318	4.283e-232	752.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_1533773_7	861299.J421_2906	8.081e-84	286.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS3_k127_1533773_5	861299.J421_2904	3.044e-124	415.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS3_k127_1533773_2	379066.GAU_1147	3.058e-156	503.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GDHHQS3_k127_1533773_4	1379270.AUXF01000005_gene457	1.906e-134	434.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1533773_3	379066.GAU_3472	9.021e-155	505.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1533773_0	379066.GAU_3473	1.33e-180	578.0	COG0577@1|root,COG0577@2|Bacteria,1ZT67@142182|Gemmatimonadetes	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1533773_6	861299.J421_6166	3.982e-105	353.0	COG0628@1|root,COG0628@2|Bacteria,1ZSY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_1533773_1	861299.J421_1415	2.418e-176	561.0	COG0577@1|root,COG0577@2|Bacteria,1ZUG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1533773_8	861299.J421_1414	3.011e-61	220.0	COG0577@1|root,COG0577@2|Bacteria,1ZUCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1550989_0	1121123.AUAO01000006_gene1954	1.177e-101	337.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2KFS1@204458|Caulobacterales	204458|Caulobacterales	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_1550989_1	1384056.N787_12445	1.104e-67	241.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RXCB@1236|Gammaproteobacteria,1X4WJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the AB hydrolase superfamily. MetX family	metXS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GDHHQS3_k127_1565121_2	861299.J421_2927	4.545e-87	293.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS3_k127_1565121_0	357808.RoseRS_1753	1.255e-166	533.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,374V4@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_1565121_3	1379270.AUXF01000005_gene487	4.898e-79	278.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
GDHHQS3_k127_1565121_1	861299.J421_2930	2.993e-139	451.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_157085_5	379066.GAU_1932	3.278e-42	166.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_157085_4	861299.J421_3542	2.088e-68	260.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS3_k127_157085_3	1379270.AUXF01000006_gene25	3.422e-152	493.0	COG1228@1|root,COG1228@2|Bacteria,1ZSNQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GDHHQS3_k127_157085_2	861299.J421_3544	4.049e-164	521.0	COG0535@1|root,COG0535@2|Bacteria,1ZT6Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_157085_0	379066.GAU_1936	9.355e-275	854.0	COG2987@1|root,COG2987@2|Bacteria,1ZSQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS3_k127_157085_1	861299.J421_3546	1.062e-216	686.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GDHHQS3_k127_157085_6	596151.DesfrDRAFT_3749	4.778e-10	65.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,42MQE@68525|delta/epsilon subdivisions,2WJGC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
GDHHQS3_k127_158058_1	671143.DAMO_3123	5.458e-104	357.0	COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_158058_0	330214.NIDE3162	6.095e-155	506.0	COG3850@1|root,COG4251@1|root,COG3850@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K14978	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	CHASE8,DUF3365,GAF_2,HAMP,HATPase_c,HisKA,PilJ,Response_reg,SpoIIE
GDHHQS3_k127_158797_5	234267.Acid_4350	1.254e-54	199.0	COG0560@1|root,COG0560@2|Bacteria,3Y6IV@57723|Acidobacteria	57723|Acidobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS3_k127_158797_0	485917.Phep_4006	0.0	1313.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1INMT@117747|Sphingobacteriia	976|Bacteroidetes	HP	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_158797_1	485917.Phep_4005	5.736e-217	691.0	COG1435@1|root,COG1435@2|Bacteria,4NE4F@976|Bacteroidetes,1IQUZ@117747|Sphingobacteriia	976|Bacteroidetes	F	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
GDHHQS3_k127_158797_2	861299.J421_6260	2.604e-155	499.0	COG3842@1|root,COG3842@2|Bacteria,1ZU03@142182|Gemmatimonadetes	2|Bacteria	E	ABC transporter	-	-	-	ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_158797_4	861299.J421_6261	1.721e-128	423.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	ycjP_4	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_158797_3	861299.J421_6262	1.404e-140	450.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GDHHQS3_k127_158797_6	518766.Rmar_0358	9.902e-47	177.0	COG1653@1|root,COG1653@2|Bacteria,4NJ41@976|Bacteroidetes	976|Bacteroidetes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
GDHHQS3_k127_1594870_2	1123278.KB893511_gene1479	6.096e-37	156.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,47P40@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_1594870_0	1288494.EBAPG3_1360	0.0	1174.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GDHHQS3_k127_1594870_1	1123278.KB893609_gene4504	6.423e-48	176.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,47NZB@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
GDHHQS3_k127_159922_1	861299.J421_2997	2.054e-227	721.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_159922_2	861299.J421_2996	4.882e-61	235.0	2FBQ3@1|root,343V1@2|Bacteria,1ZU1R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS3_k127_159922_0	861299.J421_2994	4.75e-261	813.0	COG0525@1|root,COG0525@2|Bacteria,1ZSXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS3_k127_1670577_1	596151.DesfrDRAFT_0692	3.607e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1R900@1224|Proteobacteria,42PXF@68525|delta/epsilon subdivisions,2WKEF@28221|Deltaproteobacteria,2MAQ2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
GDHHQS3_k127_1670577_0	861299.J421_3866	3.198e-201	644.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_169311_1	861299.J421_5622	8.145e-65	241.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5622|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_169311_0	251221.35214309	6.164e-87	316.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS3_k127_169311_3	379066.GAU_0150	2.621e-30	126.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
GDHHQS3_k127_169311_2	1379270.AUXF01000003_gene3371	6.822e-63	224.0	COG0745@1|root,COG0745@2|Bacteria,1ZUZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1703590_10	861299.J421_4381	8.695e-25	107.0	COG2154@1|root,COG2154@2|Bacteria,1ZU5C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS3_k127_1703590_2	861299.J421_5976	3.217e-113	376.0	COG1533@1|root,COG1533@2|Bacteria,1ZUFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_1703590_12	379066.GAU_0475	6.143e-08	59.0	2900U@1|root,2ZMR2@2|Bacteria,1ZU6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1703590_3	379066.GAU_0474	3.141e-87	300.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_1703590_7	927658.AJUM01000021_gene968	5.473e-49	188.0	COG0863@1|root,COG3392@1|root,COG0863@2|Bacteria,COG3392@2|Bacteria,4PIKF@976|Bacteroidetes,2G1FK@200643|Bacteroidia,3XM01@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GDHHQS3_k127_1703590_4	861299.J421_1544	2.648e-73	262.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	envE	-	3.1.4.46,3.2.1.18,3.2.1.8	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	-	R01030,R01470,R04018	RC00017,RC00028,RC00077,RC00425	ko00000,ko00001,ko01000,ko02042	-	GH33	-	GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH
GDHHQS3_k127_1703590_1	861299.J421_2379	9.011e-141	455.0	COG1804@1|root,COG1804@2|Bacteria,1ZT8E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS3_k127_1703590_9	861299.J421_2378	3.318e-31	130.0	2F43E@1|root,33WUY@2|Bacteria,1ZTT4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1703590_0	861299.J421_2374	1.434e-141	458.0	COG0624@1|root,COG0624@2|Bacteria,1ZSZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_1703590_11	861299.J421_2373	8.043e-18	84.0	28UVI@1|root,2ZGZI@2|Bacteria,1ZU6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1703590_5	861299.J421_2372	1.19e-68	239.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GDHHQS3_k127_1703590_8	861299.J421_2370	1.008e-33	138.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1703590_6	391625.PPSIR1_32759	6.14e-61	223.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_1714012_1	861299.J421_2798	1.465e-07	53.0	COG0483@1|root,COG0483@2|Bacteria,1ZTQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS3_k127_1714012_0	861299.J421_2797	3.262e-203	641.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,1ZT04@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS3_k127_1717237_0	861299.J421_2697	2.146e-253	806.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS3_k127_1717237_1	861299.J421_2698	5.707e-112	372.0	COG0454@1|root,COG0454@2|Bacteria,1ZSVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_1717237_2	1379270.AUXF01000002_gene1566	3.66e-80	274.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1566|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS3_k127_1810774_1	861299.J421_3310	3.271e-155	494.0	COG0057@1|root,COG0057@2|Bacteria,1ZSTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_1810774_4	861299.J421_3311	1.237e-80	277.0	COG1040@1|root,COG1040@2|Bacteria,1ZTS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS3_k127_1810774_5	861299.J421_3312	3.658e-78	271.0	COG0169@1|root,COG0169@2|Bacteria,1ZTVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
GDHHQS3_k127_1810774_7	861299.J421_3313	4.321e-46	170.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS3_k127_1810774_3	861299.J421_3314	7.201e-100	330.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
GDHHQS3_k127_1810774_2	379066.GAU_1684	6.223e-100	331.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
GDHHQS3_k127_1810774_0	861299.J421_3316	2.641e-231	729.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
GDHHQS3_k127_1810774_6	379066.GAU_1686	7.786e-70	239.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS3_k127_18424_6	315730.BcerKBAB4_3287	1.027e-05	58.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_18424_2	861299.J421_3739	2.157e-58	222.0	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,RCC1,RCC1_2
GDHHQS3_k127_18424_1	1123261.AXDW01000010_gene354	4.025e-64	246.0	2C45E@1|root,34056@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_18424_0	420324.KI911965_gene544	8.051e-126	404.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,1JUHK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	MA20_35715	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
GDHHQS3_k127_18424_4	1232410.KI421412_gene169	7.217e-42	156.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_1843734_2	479434.Sthe_0342	3.077e-36	139.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS3_k127_1843734_4	485913.Krac_4003	6.258e-18	87.0	2E4G6@1|root,335WF@2|Bacteria,2G9R2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1843734_1	351160.RCIX322	6.464e-45	173.0	COG0428@1|root,arCOG00576@2157|Archaea,2XX28@28890|Euryarchaeota,2NAV5@224756|Methanomicrobia	224756|Methanomicrobia	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
GDHHQS3_k127_1843734_0	420324.KI912082_gene6957	6.997e-231	723.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,1JUZ2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
GDHHQS3_k127_1843734_3	936136.ARRT01000006_gene3588	9.861e-20	91.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TS0V@28211|Alphaproteobacteria,4B8G6@82115|Rhizobiaceae	28211|Alphaproteobacteria	CO	Cytochrome c biogenesis protein	dipZ	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
GDHHQS3_k127_1851082_3	1379270.AUXF01000006_gene31	3.88e-35	153.0	COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS3_k127_1851082_2	1379270.AUXF01000006_gene32	1.477e-49	186.0	COG0757@1|root,COG0757@2|Bacteria,1ZTVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GDHHQS3_k127_1851082_0	861299.J421_3535	6.191e-153	490.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_1851082_1	379066.GAU_1925	2.251e-64	224.0	COG0511@1|root,COG0511@2|Bacteria,1ZTR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS3_k127_1851082_4	1379270.AUXF01000006_gene35	4.944e-07	52.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_1912168_6	1279017.AQYJ01000028_gene2525	3.915e-94	318.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_1912168_5	204669.Acid345_1383	1.739e-111	366.0	2CEY7@1|root,2Z8CG@2|Bacteria,3Y70V@57723|Acidobacteria,2JKPR@204432|Acidobacteriia	204432|Acidobacteriia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1912168_1	204669.Acid345_1384	1.529e-305	944.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_1912168_4	204669.Acid345_1385	4.044e-120	391.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS3_k127_1912168_3	861299.J421_6171	9.682e-140	456.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_6171|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1912168_0	861299.J421_1402	0.0	1190.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_1912168_8	379066.GAU_0537	3.887e-25	110.0	2C4KS@1|root,30283@2|Bacteria,1ZUZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1912168_2	861299.J421_4089	3.356e-164	527.0	COG1680@1|root,COG1680@2|Bacteria,1ZUDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_19542_13	1198452.Jab_2c16090	3.085e-33	131.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2W97I@28216|Betaproteobacteria,475FN@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_19542_2	1380390.JIAT01000014_gene6208	1.818e-237	753.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,NB-ARC,Response_reg,TIR_2,TPR_10,TPR_12
GDHHQS3_k127_19542_9	1380390.JIAT01000014_gene6209	5.806e-98	327.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_19542_4	886293.Sinac_2104	5.163e-166	550.0	COG1680@1|root,COG1680@2|Bacteria,2IWSV@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_19542_7	861299.J421_4030	2.866e-121	419.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
GDHHQS3_k127_19542_1	861299.J421_4031	3.981e-305	948.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
GDHHQS3_k127_19542_11	604354.TSIB_1211	3.189e-50	190.0	arCOG09492@1|root,arCOG09492@2157|Archaea,2Y3AH@28890|Euryarchaeota,244X9@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_19542_0	861299.J421_4032	0.0	1533.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4032|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_19542_8	1379270.AUXF01000001_gene2274	1.076e-107	364.0	28M5H@1|root,2ZAJ9@2|Bacteria,1ZUWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_19542_3	1379270.AUXF01000001_gene2272	6.658e-183	586.0	COG1524@1|root,COG1524@2|Bacteria,1ZUMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_19542_10	1144275.COCOR_01812	1.941e-57	214.0	COG1680@1|root,COG1680@2|Bacteria,1RGG3@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_19542_6	861299.J421_6191	2.327e-128	426.0	COG1413@1|root,COG1413@2|Bacteria,1ZUDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_19542_5	379066.GAU_0985	3.085e-134	454.0	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria,1ZUUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Peptidase_M56
GDHHQS3_k127_19542_12	379066.GAU_0984	6.556e-35	135.0	COG3682@1|root,COG3682@2|Bacteria,1ZV5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS3_k127_1980045_2	861299.J421_4178	1.25e-53	192.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GDHHQS3_k127_1980045_3	861299.J421_4179	2.194e-51	188.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1980045_1	861299.J421_4180	3.456e-62	224.0	COG1836@1|root,COG1836@2|Bacteria,1ZTT3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS3_k127_1980045_0	443143.GM18_0875	3.266e-67	253.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS3_k127_199872_2	314271.RB2654_02874	5.044e-09	58.0	COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria	1224|Proteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
GDHHQS3_k127_199872_0	1123393.KB891328_gene562	5.041e-44	162.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KSZH@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_20,Thioredoxin
GDHHQS3_k127_2055479_0	861299.J421_3834	1.13e-74	259.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS3_k127_2055479_1	234267.Acid_4011	4.434e-33	131.0	COG3503@1|root,COG3503@2|Bacteria,3Y3XK@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS3_k127_2086644_0	693986.MOC_5568	1.315e-166	531.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,1JU8R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_2086644_1	1144275.COCOR_01812	5.494e-77	270.0	COG1680@1|root,COG1680@2|Bacteria,1RGG3@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_2095560_0	861299.J421_5955	4.906e-135	431.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_2095560_3	1267535.KB906767_gene3676	1.806e-49	193.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_2095560_1	861299.J421_5954	4.627e-103	341.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	-	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS3_k127_2095560_4	861299.J421_1380	7.505e-49	187.0	COG3142@1|root,COG3142@2|Bacteria,1ZTRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
GDHHQS3_k127_2095560_2	204669.Acid345_2325	4.414e-101	333.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_212286_4	861299.J421_4476	4.807e-06	51.0	COG2318@1|root,COG2318@2|Bacteria,1ZU06@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_212286_2	1242864.D187_003015	4.856e-99	349.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4
GDHHQS3_k127_212286_1	419610.Mext_1974	5.414e-113	377.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,1JR9D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
GDHHQS3_k127_212286_3	861299.J421_6331	6.361e-54	193.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS3_k127_212286_0	861299.J421_3418	5.692e-193	606.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_217258_0	861299.J421_3428	1.316e-143	459.0	COG0624@1|root,COG0624@2|Bacteria,1ZSV0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_217258_4	1267534.KB906759_gene1703	3.101e-44	176.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_217258_6	1120970.AUBZ01000022_gene1300	4.669e-08	65.0	COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,1RMUN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
GDHHQS3_k127_217258_3	1121904.ARBP01000004_gene934	1.146e-45	183.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NEX2@976|Bacteroidetes,47NV4@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_217258_1	404589.Anae109_3731	1.151e-56	209.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
GDHHQS3_k127_2245834_1	861299.J421_1729	3.904e-23	115.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_2245834_0	861299.J421_0666	2.08e-182	578.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2245834_2	861299.J421_0665	2.031e-18	93.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
GDHHQS3_k127_2253183_0	357808.RoseRS_3832	1.78e-105	350.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi,3768T@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_2253183_6	751944.HALDL1_16545	4.127e-17	91.0	arCOG05875@1|root,arCOG05876@1|root,arCOG05875@2157|Archaea,arCOG05876@2157|Archaea,2XWFY@28890|Euryarchaeota,23UNU@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
GDHHQS3_k127_2253183_2	351160.RCIX1071	1.801e-42	175.0	arCOG05876@1|root,arCOG05876@2157|Archaea	2157|Archaea	-	-	-	-	-	ko:K16905,ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_2253183_7	1125863.JAFN01000001_gene2235	3.095e-12	73.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GDHHQS3_k127_2253183_3	1232437.KL661966_gene3144	4.167e-42	161.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
GDHHQS3_k127_2253183_4	1206733.BAGC01000044_gene848	1.588e-39	153.0	2EHMA@1|root,33BD2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_2253183_5	517418.Ctha_0741	1.066e-23	109.0	COG2010@1|root,COG2010@2|Bacteria,1FEAI@1090|Chlorobi	1090|Chlorobi	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
GDHHQS3_k127_2253183_1	926560.KE387023_gene2407	1.126e-46	179.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS3_k127_2256076_0	1499686.BN1079_03359	2.305e-186	610.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_2256076_1	1122175.ATXU01000007_gene175	6.931e-11	63.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4FKAF@85023|Microbacteriaceae	201174|Actinobacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS3_k127_2262925_0	1147.D082_21510	1.001e-116	385.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	yteR	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
GDHHQS3_k127_2262925_1	1207076.ALAT01000184_gene2792	1.294e-73	255.0	2DMRI@1|root,32T77@2|Bacteria,1N4QH@1224|Proteobacteria,1S9U1@1236|Gammaproteobacteria,1Z0R9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GDHHQS3_k127_2262925_2	398767.Glov_3470	4.629e-30	130.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS3_k127_2264556_5	1379270.AUXF01000005_gene670	7.641e-13	74.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
GDHHQS3_k127_2264556_4	383372.Rcas_1731	2.241e-34	141.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS3_k127_2264556_2	861299.J421_3059	1.648e-81	275.0	COG1100@1|root,COG1100@2|Bacteria,1ZTK3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
GDHHQS3_k127_2264556_1	1379270.AUXF01000005_gene674	5.559e-88	306.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
GDHHQS3_k127_2264556_0	861299.J421_3062	2.665e-88	303.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GDHHQS3_k127_2264556_3	1379270.AUXF01000005_gene676	8.451e-59	211.0	COG2201@1|root,COG2201@2|Bacteria,1ZUFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS3_k127_2267024_0	861299.J421_2757	5.999e-219	687.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
GDHHQS3_k127_2267024_1	290397.Adeh_0636	4.335e-18	89.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_2267483_2	633149.Bresu_0594	5.951e-113	370.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_2267483_4	1379270.AUXF01000002_gene1599	2.122e-91	311.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1599|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2267483_0	861299.J421_1822	4.041e-297	944.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_2267483_3	861299.J421_1823	1.939e-93	323.0	28P8D@1|root,2ZC2C@2|Bacteria,1ZUEX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2267483_6	981223.AIED01000038_gene469	0.00013	51.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,3NMFU@468|Moraxellaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_2267483_1	861299.J421_2569	2.73e-174	555.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS3_k127_2267483_5	379066.GAU_0626	2.702e-35	137.0	COG1862@1|root,COG1862@2|Bacteria,1ZU5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS3_k127_2290292_2	861299.J421_3284	1.071e-176	564.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_2290292_3	861299.J421_3283	2.173e-176	571.0	COG1008@1|root,COG1008@2|Bacteria,1ZUBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_2290292_4	861299.J421_3282	2.435e-170	548.0	COG1007@1|root,COG1007@2|Bacteria,1ZSVJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_2290292_0	379066.GAU_1648	3.17e-198	634.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_2290292_11	1379270.AUXF01000006_gene244	1.186e-82	297.0	COG1615@1|root,COG1615@2|Bacteria,1ZTEE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS3_k127_2290292_12	1379698.RBG1_1C00001G0473	2.579e-72	259.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
GDHHQS3_k127_2290292_1	861299.J421_3279	4.48e-182	577.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS3_k127_2290292_6	379066.GAU_1645	6.798e-147	472.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS3_k127_2290292_13	1379270.AUXF01000006_gene247	9.498e-56	197.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS3_k127_2290292_14	861299.J421_3275	2.089e-50	184.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS3_k127_2290292_16	861299.J421_3274	5.055e-25	104.0	COG0333@1|root,COG0333@2|Bacteria,1ZU2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS3_k127_2290292_7	1379270.AUXF01000006_gene250	5.467e-131	426.0	COG0416@1|root,COG0416@2|Bacteria,1ZSN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS3_k127_2290292_5	861299.J421_3272	1.201e-154	497.0	COG0332@1|root,COG0332@2|Bacteria,1ZSP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS3_k127_2290292_8	861299.J421_3271	1.771e-116	386.0	COG0331@1|root,COG0331@2|Bacteria,1ZT40@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS3_k127_2290292_10	861299.J421_3270	3.326e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_2290292_15	861299.J421_3269	1.196e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1ZU0X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_2290292_9	997346.HMPREF9374_0894	2.061e-112	370.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_2305072_1	379066.GAU_1150	1.074e-167	567.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS3_k127_2305072_0	861299.J421_2908	1.52e-215	689.0	COG0515@1|root,COG0515@2|Bacteria,1ZTB4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_2315775_0	861299.J421_3250	3.465e-208	651.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GDHHQS3_k127_2315775_1	861299.J421_3249	3.33e-133	433.0	COG0463@1|root,COG0463@2|Bacteria,1ZTEI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2315775_2	861299.J421_3248	5.481e-111	371.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_2315775_3	379066.GAU_1614	4.461e-50	192.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_2318967_2	861299.J421_3922	4.554e-80	269.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GDHHQS3_k127_2318967_4	861299.J421_3923	2.152e-43	170.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2318967_3	861299.J421_3925	5.659e-59	207.0	COG0720@1|root,COG0720@2|Bacteria,1ZTRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_2318967_0	861299.J421_3926	2.869e-114	383.0	COG2027@1|root,COG2027@2|Bacteria,1ZSQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS3_k127_2318967_1	861299.J421_3927	3.067e-108	369.0	COG0303@1|root,COG0303@2|Bacteria,1ZT4D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS3_k127_2318967_6	1379270.AUXF01000003_gene3462	4.766e-37	149.0	COG3897@1|root,COG3897@2|Bacteria,1ZTUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2329220_0	234267.Acid_3931	1.075e-279	878.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS3_k127_2329220_3	861299.J421_6109	6.387e-84	285.0	COG3279@1|root,COG3279@2|Bacteria,1ZUZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS3_k127_2329220_2	861299.J421_6108	5.647e-91	312.0	COG2972@1|root,COG2972@2|Bacteria,1ZUX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
GDHHQS3_k127_2329220_1	861299.J421_5713	5.195e-143	469.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_2329220_4	861299.J421_6107	6.95e-39	152.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
GDHHQS3_k127_2329220_5	379066.GAU_1259	4.258e-27	113.0	COG0008@1|root,COG0008@2|Bacteria,1ZSSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS3_k127_2334832_2	324925.Ppha_2833	2.932e-88	299.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_2334832_0	861299.J421_0859	2.676e-124	406.0	COG0346@1|root,COG0346@2|Bacteria,1ZTUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS3_k127_2334832_1	215803.DB30_8674	3.102e-109	367.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YUIF@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_233935_3	861299.J421_0144	2.238e-42	157.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_233935_1	861299.J421_3568	1.047e-57	209.0	COG4105@1|root,COG4105@2|Bacteria,1ZTMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
GDHHQS3_k127_233935_2	861299.J421_3567	3.298e-56	205.0	COG1057@1|root,COG1057@2|Bacteria,1ZTT1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_233935_0	861299.J421_3566	4.842e-313	968.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS3_k127_233945_4	861299.J421_2594	1.217e-08	62.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS3_k127_233945_1	868131.MSWAN_2422	6.611e-114	377.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23NNK@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_233945_2	861299.J421_2213	5.435e-105	355.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_2213|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_233945_0	861299.J421_2593	6.728e-136	446.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GDHHQS3_k127_233945_3	379066.GAU_0644	1.431e-73	256.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_2340580_0	861299.J421_3778	1.499e-225	714.0	COG1132@1|root,COG1132@2|Bacteria,1ZSZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2340580_2	861299.J421_3777	1.491e-96	323.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_2340580_6	1379270.AUXF01000003_gene3675	3.319e-13	74.0	2CFMP@1|root,2ZEHG@2|Bacteria,1ZU7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2340580_3	234267.Acid_5343	3.956e-71	248.0	COG4430@1|root,COG4430@2|Bacteria,3Y88Z@57723|Acidobacteria	57723|Acidobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_2340580_1	379066.GAU_2123	2.471e-176	560.0	COG3185@1|root,COG3185@2|Bacteria,1ZT62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
GDHHQS3_k127_2340580_5	861299.J421_3702	1.496e-31	124.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS3_k127_2348283_0	861299.J421_1682	3.774e-43	164.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
GDHHQS3_k127_2348283_1	861299.J421_5847	1.073e-35	144.0	2E3HM@1|root,30MSF@2|Bacteria,1ZV6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2348283_2	1120965.AUBV01000001_gene3520	5.189e-16	87.0	2DUH4@1|root,33QM8@2|Bacteria,4NPKV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS3_k127_2349177_0	349163.Acry_2829	5.661e-135	438.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2JRG6@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_2349177_5	1458427.BAWN01000012_gene707	2.154e-16	91.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,2VU9J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_2349177_2	365046.Rta_06020	9.019e-112	369.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2349177_6	861299.J421_4052	1.584e-11	69.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_4052|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2349177_3	379066.GAU_3607	9.195e-79	280.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_2349177_4	1041930.Mtc_1962	1.554e-28	120.0	COG0526@1|root,arCOG01976@2157|Archaea	2157|Archaea	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	TPR_16,Thioredoxin_2,Thioredoxin_7
GDHHQS3_k127_2349177_7	1245469.S58_42410	3.284e-05	48.0	2AFMZ@1|root,313VJ@2|Bacteria,1N8AX@1224|Proteobacteria,2UH2P@28211|Alphaproteobacteria,3K1GV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2349177_1	1163408.UU9_09862	1.717e-112	375.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,1X3Q6@135614|Xanthomonadales	135614|Xanthomonadales	E	Dipeptidyl carboxypeptidase	dcp2	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS3_k127_2355792_10	460265.Mnod_5265	1.125e-13	70.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,1JSUK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GMC oxidoreductase family	MA20_15975	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_2355792_6	391735.Veis_2326	9.484e-27	114.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4ADVR@80864|Comamonadaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GDHHQS3_k127_2355792_9	391735.Veis_3844	8.91e-15	84.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
GDHHQS3_k127_2355792_1	391735.Veis_4503	5.602e-42	155.0	COG3415@1|root,COG3415@2|Bacteria,1QWK4@1224|Proteobacteria,2WH2V@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	HTH_29,HTH_32
GDHHQS3_k127_2355792_2	1500301.JQMF01000025_gene6086	1.11e-39	158.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,4BFJ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_2355792_7	1403819.BATR01000075_gene2193	2.096e-24	108.0	COG3779@1|root,COG3779@2|Bacteria,46X04@74201|Verrucomicrobia,2IW8T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
GDHHQS3_k127_2355792_0	1185876.BN8_01934	9.911e-59	212.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_2355792_13	235909.GK0964	0.0003521	45.0	COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1WG1C@129337|Geobacillus	91061|Bacilli	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
GDHHQS3_k127_2355792_3	626418.bglu_2g02890	4.692e-33	134.0	COG4405@1|root,COG4405@2|Bacteria,1N2T4@1224|Proteobacteria,2VW9U@28216|Betaproteobacteria,1K9YA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
GDHHQS3_k127_2355792_12	640081.Dsui_2916	1.185e-09	64.0	2DZXG@1|root,32VMH@2|Bacteria,1N50I@1224|Proteobacteria,2VXVV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2355792_4	483219.LILAB_20800	2.492e-32	135.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_2355792_5	1121015.N789_10840	5.418e-28	118.0	COG5646@1|root,COG5646@2|Bacteria,1Q32P@1224|Proteobacteria,1TE2U@1236|Gammaproteobacteria,1XBCC@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_2355792_8	452637.Oter_3914	1.384e-17	87.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_2360863_0	861299.J421_2945	8.196e-161	516.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS3_k127_2360863_1	379066.GAU_1191	1.019e-155	496.0	COG2876@1|root,COG2876@2|Bacteria,1ZTB0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS3_k127_2386860_2	1230342.CTM_19939	2.951e-32	129.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,36EQM@31979|Clostridiaceae	186801|Clostridia	F	PFAM amidohydrolase	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
GDHHQS3_k127_2386860_0	266117.Rxyl_0222	1.97e-192	613.0	COG1953@1|root,COG1953@2|Bacteria,2GJXN@201174|Actinobacteria	201174|Actinobacteria	FH	permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GDHHQS3_k127_2386860_1	234267.Acid_7663	3.647e-147	469.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GDHHQS3_k127_2386860_3	504728.K649_03245	3.212e-26	109.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_2428922_10	378806.STAUR_6505	2.251e-54	195.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,43A1M@68525|delta/epsilon subdivisions,2X25R@28221|Deltaproteobacteria,2YUPF@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_2428922_16	1183438.GKIL_2277	2.551e-10	67.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
GDHHQS3_k127_2428922_15	1380391.JIAS01000019_gene1266	8.402e-13	81.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
GDHHQS3_k127_2428922_11	1174504.AJTN02000217_gene3143	2.624e-37	156.0	COG3577@1|root,COG3577@2|Bacteria,1VKN9@1239|Firmicutes	1239|Firmicutes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
GDHHQS3_k127_2428922_9	13035.Dacsa_2599	4.946e-59	209.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GDHHQS3_k127_2428922_8	379066.GAU_2670	8.344e-66	237.0	COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2428922_2	379066.GAU_2120	6.482e-180	578.0	COG1649@1|root,COG1649@2|Bacteria,1ZSWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GDHHQS3_k127_2428922_18	497965.Cyan7822_0539	0.0004867	48.0	28YS9@1|root,2ZKJQ@2|Bacteria,1GH2X@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2428922_3	754035.Mesau_05451	4.744e-154	497.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GDHHQS3_k127_2428922_13	497965.Cyan7822_0541	2.438e-26	112.0	COG1873@1|root,COG1873@2|Bacteria,1GEUB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2428922_14	497965.Cyan7822_0542	8.271e-22	99.0	2EM7X@1|root,33EX1@2|Bacteria,1GEMJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2428922_1	448385.sce5973	1.595e-186	593.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_2428922_0	861299.J421_3729	7.872e-220	695.0	COG0591@1|root,COG0591@2|Bacteria,1ZUAP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
GDHHQS3_k127_2428922_12	861299.J421_3730	1.608e-34	138.0	2CFMM@1|root,347ZP@2|Bacteria,1ZV4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2428922_4	1254432.SCE1572_37770	2.088e-137	461.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
GDHHQS3_k127_2428922_6	1379270.AUXF01000001_gene2286	5.004e-112	374.0	COG3817@1|root,COG3817@2|Bacteria,1ZU8S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
GDHHQS3_k127_2428922_7	1379270.AUXF01000001_gene2285	1.251e-89	301.0	COG3819@1|root,COG3819@2|Bacteria,1ZUCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
GDHHQS3_k127_2428922_5	861299.J421_6137	2.653e-137	443.0	COG1171@1|root,COG1171@2|Bacteria,1ZU14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_2432900_1	1123508.JH636439_gene1391	6.756e-134	464.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_2432900_0	379066.GAU_3334	3.052e-172	550.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_2454501_2	1121396.KB893123_gene1104	1.252e-07	58.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2MJ3K@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_2454501_0	204669.Acid345_2545	2.48e-43	166.0	COG3685@1|root,COG3685@2|Bacteria,3Y534@57723|Acidobacteria,2JJHZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
GDHHQS3_k127_2454501_1	56780.SYN_00173	1.352e-27	117.0	COG0784@1|root,COG0784@2|Bacteria,1QUK7@1224|Proteobacteria,431U0@68525|delta/epsilon subdivisions,2WW6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_2457740_4	861299.J421_3755	8.005e-61	212.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2457740_5	1379270.AUXF01000003_gene3689	8.708e-49	181.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2457740_6	1379270.AUXF01000003_gene3688	8.664e-19	90.0	298RJ@1|root,2ZVVV@2|Bacteria,1ZU7B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Molydop_binding
GDHHQS3_k127_2457740_0	861299.J421_3758	7.62e-167	534.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_2457740_3	861299.J421_3759	1.386e-86	294.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
GDHHQS3_k127_2457740_2	861299.J421_3760	6.966e-92	309.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
GDHHQS3_k127_2457740_1	1379270.AUXF01000003_gene3684	1.055e-97	340.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_2477185_4	861299.J421_3855	6.061e-10	59.0	COG0740@1|root,COG0740@2|Bacteria,1ZSPR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS3_k127_2477185_0	861299.J421_3854	2.064e-155	501.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
GDHHQS3_k127_2477185_2	1403819.BATR01000016_gene478	8.072e-48	185.0	COG3685@1|root,COG3685@2|Bacteria,46VCV@74201|Verrucomicrobia,2IVZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
GDHHQS3_k127_2477185_3	111780.Sta7437_3182	7.673e-16	84.0	2E9TG@1|root,333ZH@2|Bacteria,1GKFI@1117|Cyanobacteria,3VN2S@52604|Pleurocapsales	1117|Cyanobacteria	S	Nuclease A inhibitor-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NuiA
GDHHQS3_k127_2477185_1	861299.J421_3849	8.904e-155	504.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_2477185_5	929556.Solca_4020	6.07e-05	53.0	2DKW8@1|root,30JES@2|Bacteria,4NPM5@976|Bacteroidetes,1ITXX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2481995_2	1379270.AUXF01000001_gene2650	3.308e-80	276.0	COG4591@1|root,COG4591@2|Bacteria	1379270.AUXF01000001_gene2650|-	M	lipoprotein localization to outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2481995_1	861299.J421_4361	5.041e-81	277.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_2481995_3	1379270.AUXF01000001_gene2648	1.428e-52	196.0	COG0589@1|root,COG0589@2|Bacteria,1ZTUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_2481995_0	861299.J421_4364	1.113e-203	642.0	COG1914@1|root,COG1914@2|Bacteria,1ZT3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
GDHHQS3_k127_2499458_9	379066.GAU_2543	1.12e-39	159.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS3_k127_2499458_1	861299.J421_1919	6.747e-171	542.0	COG2132@1|root,COG2132@2|Bacteria,1ZTWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_2499458_8	1382356.JQMP01000003_gene1429	4.776e-46	186.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS3_k127_2499458_5	861299.J421_1920	8.359e-90	301.0	COG2197@1|root,COG2197@2|Bacteria,1ZSRV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_2499458_4	472759.Nhal_2486	1.823e-112	387.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_2499458_2	666685.R2APBS1_3302	1.417e-132	442.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1X5RA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS3_k127_2499458_6	546414.Deide_21390	3.196e-54	203.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GDHHQS3_k127_2499458_0	861299.J421_2513	1.182e-222	700.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS3_k127_2499458_3	861299.J421_2514	2.805e-120	398.0	COG0477@1|root,COG2814@2|Bacteria,1ZSUR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_2499458_7	743719.PaelaDRAFT_1340	7.891e-51	191.0	2BWG6@1|root,32WUM@2|Bacteria,1VBBF@1239|Firmicutes,4HNFJ@91061|Bacilli,26UFI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2510922_1	861299.J421_2451	1.645e-218	691.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_2510922_6	861299.J421_4175	6.379e-47	181.0	COG3794@1|root,COG3794@2|Bacteria,1ZTXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_2510922_0	861299.J421_4174	1.478e-223	719.0	COG1132@1|root,COG1132@2|Bacteria,1ZSP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2510922_3	861299.J421_4172	3.437e-139	447.0	COG0109@1|root,COG0109@2|Bacteria,1ZSP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS3_k127_2510922_5	379066.GAU_2580	7.593e-66	237.0	COG1612@1|root,COG1612@2|Bacteria,1ZURE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS3_k127_2510922_2	861299.J421_4169	8.743e-209	658.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_2510922_4	861299.J421_4168	7.386e-125	415.0	COG1629@1|root,COG4771@2|Bacteria,1ZSNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS3_k127_2530045_6	1122939.ATUD01000009_gene3064	1.507e-38	161.0	COG1413@1|root,COG1413@2|Bacteria,2IHYB@201174|Actinobacteria	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_2530045_3	1146883.BLASA_1780	3.073e-93	331.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
GDHHQS3_k127_2530045_4	1283300.ATXB01000002_gene3188	3.709e-55	197.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XEYU@135618|Methylococcales	135618|Methylococcales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS3_k127_2530045_1	99598.Cal7507_2182	3.661e-274	863.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1HJE5@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_2530045_5	861299.J421_2472	1.516e-48	181.0	COG0762@1|root,COG0762@2|Bacteria,1ZTUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS3_k127_2530045_7	522306.CAP2UW1_3597	7.989e-16	88.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS3_k127_2530045_0	1382306.JNIM01000001_gene665	0.0	1390.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS3_k127_2530045_2	1379270.AUXF01000004_gene3330	2.572e-227	713.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS3_k127_253739_3	1121406.JAEX01000001_gene113	1.251e-181	595.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2M7WP@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_253739_4	861299.J421_2655	1.622e-157	501.0	COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
GDHHQS3_k127_253739_5	1379270.AUXF01000004_gene3143	8.178e-132	429.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS3_k127_253739_1	861299.J421_2653	4.926e-221	695.0	COG0143@1|root,COG0143@2|Bacteria,1ZTDB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
GDHHQS3_k127_253739_8	1379270.AUXF01000001_gene2088	2.118e-07	59.0	2DDI2@1|root,2ZI6I@2|Bacteria,1ZVAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_253739_0	861299.J421_0487	0.0	1031.0	COG2936@1|root,COG2936@2|Bacteria,1ZUE2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
GDHHQS3_k127_253739_6	379066.GAU_1463	2.659e-55	212.0	28II1@1|root,2Z8J7@2|Bacteria,1ZUX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
GDHHQS3_k127_253739_2	1297742.A176_02902	3.26e-207	679.0	COG4206@1|root,COG4206@2|Bacteria,1QXUW@1224|Proteobacteria,43C7J@68525|delta/epsilon subdivisions,2X7HV@28221|Deltaproteobacteria,2YU5W@29|Myxococcales	28221|Deltaproteobacteria	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_253739_7	861299.J421_2645	3.992e-15	76.0	COG1704@1|root,COG1704@2|Bacteria,1ZTQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS3_k127_254112_1	861299.J421_0900	1.556e-249	779.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS3_k127_254112_12	292.DM42_5541	1.42e-07	61.0	28M17@1|root,2ZAG4@2|Bacteria,1PNNF@1224|Proteobacteria,2VZYD@28216|Betaproteobacteria,1KD7C@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_254112_4	861299.J421_1806	1.054e-63	229.0	COG3258@1|root,COG3258@2|Bacteria,1ZUR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS3_k127_254112_5	257310.BB4478	7.046e-56	210.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2VQ3S@28216|Betaproteobacteria,3T1BU@506|Alcaligenaceae	28216|Betaproteobacteria	E	Allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B
GDHHQS3_k127_254112_6	926569.ANT_23220	8.807e-48	180.0	COG2049@1|root,COG2049@2|Bacteria,2G7CU@200795|Chloroflexi	200795|Chloroflexi	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
GDHHQS3_k127_254112_3	580340.Tlie_0278	7.789e-75	259.0	COG1540@1|root,COG1540@2|Bacteria,3T9Q0@508458|Synergistetes	508458|Synergistetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
GDHHQS3_k127_254112_7	1038859.AXAU01000015_gene933	4.033e-34	132.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,2UDCH@28211|Alphaproteobacteria,3K0FK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_254112_11	1121373.KB903665_gene3086	4.511e-11	76.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GDHHQS3_k127_254112_0	861299.J421_2988	7.318e-319	992.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_254112_2	1379270.AUXF01000005_gene585	3.835e-228	717.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS3_k127_2619314_4	861299.J421_0447	7.39e-16	78.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_2619314_3	861299.J421_0446	1.439e-68	242.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2619314_0	861299.J421_0438	0.0	1076.0	COG3968@1|root,COG3968@2|Bacteria,1ZSPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
GDHHQS3_k127_2619314_1	1379270.AUXF01000002_gene1477	1.038e-237	740.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_2619314_5	1123261.AXDW01000001_gene1026	2.988e-15	78.0	2EIK5@1|root,33CBF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2619314_2	379066.GAU_3908	1.22e-103	360.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS3_k127_2635791_2	861299.J421_2680	7.372e-60	212.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_2635791_1	861299.J421_2681	1.235e-89	304.0	COG1173@1|root,COG1173@2|Bacteria,1ZTMP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_2635791_0	861299.J421_2682	1.316e-101	340.0	COG0601@1|root,COG0601@2|Bacteria,1ZTP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_2635791_3	861299.J421_2683	3.403e-38	149.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_2635873_0	1242864.D187_000199	4.183e-203	651.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
GDHHQS3_k127_2635873_1	379066.GAU_2758	1.405e-177	568.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GDHHQS3_k127_2635873_2	1341151.ASZU01000025_gene2986	1.905e-48	186.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,27B0F@186824|Thermoactinomycetaceae	91061|Bacilli	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
GDHHQS3_k127_2641542_0	1121920.AUAU01000027_gene1480	1.368e-164	546.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000027_gene1480|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2641542_1	861299.J421_3864	2.257e-88	304.0	COG2804@1|root,COG2804@2|Bacteria,1ZT2F@142182|Gemmatimonadetes	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_2680666_22	379066.GAU_1721	8.876e-21	100.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_2680666_9	1379270.AUXF01000006_gene168	1.905e-122	412.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_2680666_4	379066.GAU_1723	2.617e-196	618.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_2680666_21	637390.AFOH01000130_gene1959	2.499e-25	113.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,2NCVN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS3_k127_2680666_16	1379270.AUXF01000006_gene165	7.454e-73	256.0	COG0134@1|root,COG0134@2|Bacteria,1ZTMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS3_k127_2680666_13	861299.J421_3366	1.27e-97	322.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_2680666_8	861299.J421_3367	3.342e-124	407.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS3_k127_2680666_17	1379270.AUXF01000006_gene162	2.824e-51	193.0	COG3605@1|root,COG3605@2|Bacteria,1ZT8P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
GDHHQS3_k127_2680666_10	861299.J421_3369	3.594e-110	361.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS3_k127_2680666_18	861299.J421_3370	2.796e-49	183.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023	2.2.1.2	ko:K00616,ko:K08313,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501	TAL_FSA
GDHHQS3_k127_2680666_5	379066.GAU_1730	2.541e-159	517.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_2680666_3	379066.GAU_1731	1.128e-216	686.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS3_k127_2680666_6	861299.J421_3374	1.38e-128	422.0	COG0152@1|root,COG0152@2|Bacteria,1ZT6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS3_k127_2680666_14	861299.J421_3375	1.581e-84	286.0	COG0688@1|root,COG0688@2|Bacteria,1ZU9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS3_k127_2680666_12	379066.GAU_1734	1.064e-103	346.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_2680666_20	1379270.AUXF01000006_gene155	7.319e-28	115.0	COG1828@1|root,COG1828@2|Bacteria,1ZU3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
GDHHQS3_k127_2680666_11	861299.J421_3378	2.437e-106	349.0	COG0047@1|root,COG0047@2|Bacteria,1ZTF8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GDHHQS3_k127_2680666_1	861299.J421_3380	0.0	1161.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_2680666_2	861299.J421_3381	4.813e-228	716.0	COG0034@1|root,COG0034@2|Bacteria,1ZTD7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6
GDHHQS3_k127_2680666_0	861299.J421_3382	0.0	1344.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS3_k127_2680666_15	290397.Adeh_2418	4.115e-83	290.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_2680666_19	1122947.FR7_1481	3.029e-44	169.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
GDHHQS3_k127_2680666_23	693444.D782_3056	1.407e-05	57.0	COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,1RS5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	ybhN	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_2680666_7	278963.ATWD01000001_gene2473	4.843e-127	419.0	COG4232@1|root,COG4232@2|Bacteria,3Y771@57723|Acidobacteria	57723|Acidobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Thioredoxin_7
GDHHQS3_k127_2684068_1	1144342.PMI40_00304	0.0001297	52.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
GDHHQS3_k127_2684068_0	861299.J421_6361	9.208e-13	79.0	2F5SD@1|root,33YB8@2|Bacteria,1ZUXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2684602_5	321332.CYB_1025	7.75e-45	166.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_2684602_1	861299.J421_4186	5.232e-80	273.0	COG0580@1|root,COG0580@2|Bacteria,1ZV9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
GDHHQS3_k127_2684602_0	861299.J421_4185	9.772e-193	608.0	COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_2684602_3	861299.J421_4184	5.773e-65	229.0	COG2867@1|root,COG2867@2|Bacteria,1ZTVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
GDHHQS3_k127_2684602_2	861299.J421_4183	1.256e-73	254.0	COG0500@1|root,COG2226@2|Bacteria,1ZTP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_2684602_4	861299.J421_4182	7.712e-49	179.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS3_k127_268637_5	379066.GAU_1621	2.364e-82	281.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
GDHHQS3_k127_268637_2	379066.GAU_1623	3.124e-127	411.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS3_k127_268637_0	861299.J421_3257	1.191e-289	897.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS3_k127_268637_4	861299.J421_3258	6.297e-86	291.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS3_k127_268637_3	861299.J421_3261	9.096e-89	298.0	COG0512@1|root,COG0512@2|Bacteria,1ZTK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS3_k127_268637_1	861299.J421_3262	9.685e-150	479.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_268637_8	861299.J421_3263	1.337e-42	163.0	COG0586@1|root,COG0586@2|Bacteria,1ZTVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_268637_7	379066.GAU_1631	4.396e-60	214.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GDHHQS3_k127_268637_9	379066.GAU_1632	1.696e-36	140.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_2688805_0	483219.LILAB_35130	5.315e-45	168.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
GDHHQS3_k127_2688805_1	107635.AZUO01000001_gene431	2.767e-08	64.0	2DDTS@1|root,2ZJ8M@2|Bacteria,1NJS6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2736576_1	246197.MXAN_3277	4.245e-36	139.0	COG2128@1|root,COG2128@2|Bacteria,1Q58P@1224|Proteobacteria,43A55@68525|delta/epsilon subdivisions,2WZAF@28221|Deltaproteobacteria,2Z1PY@29|Myxococcales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2736576_2	1297742.A176_02672	1.405e-20	94.0	COG2128@1|root,COG2128@2|Bacteria,1Q58P@1224|Proteobacteria,43A55@68525|delta/epsilon subdivisions,2WZAF@28221|Deltaproteobacteria,2Z1PY@29|Myxococcales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2736576_0	1379270.AUXF01000002_gene1745	2.055e-246	785.0	COG4206@1|root,COG4206@2|Bacteria,1ZU97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_2755857_0	861299.J421_5987	1.38e-213	680.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS3_k127_2755857_1	1297865.APJD01000015_gene3469	9.521e-77	263.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
GDHHQS3_k127_2755857_2	373994.Riv7116_1583	2.485e-10	67.0	COG2947@1|root,COG2947@2|Bacteria,1G63D@1117|Cyanobacteria,1HNJU@1161|Nostocales	1117|Cyanobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS3_k127_2771111_1	861299.J421_2755	4.103e-135	443.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_2771111_2	1379270.AUXF01000004_gene3061	4.279e-85	289.0	COG1842@1|root,COG1842@2|Bacteria,1ZT82@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
GDHHQS3_k127_2771111_0	1379270.AUXF01000004_gene3064	4.082e-138	443.0	COG1760@1|root,COG1760@2|Bacteria,1ZT3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
GDHHQS3_k127_2771111_3	1379270.AUXF01000004_gene3065	5.215e-79	267.0	COG1760@1|root,COG1760@2|Bacteria,1ZTFS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
GDHHQS3_k127_277942_1	880073.Calab_0881	1.393e-94	342.0	COG0210@1|root,COG0210@2|Bacteria,2NQHW@2323|unclassified Bacteria	2|Bacteria	L	3' exoribonuclease, RNase T-like	-	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RNase_T,UvrD-helicase,UvrD_C
GDHHQS3_k127_277942_4	1267535.KB906767_gene3090	2.677e-35	138.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
GDHHQS3_k127_277942_5	1267534.KB906760_gene1554	1.975e-07	59.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_277942_2	861299.J421_1951	1.297e-50	189.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_277942_0	861299.J421_4060	0.0	1162.0	COG2352@1|root,COG2352@2|Bacteria,1ZSSH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
GDHHQS3_k127_277942_3	861299.J421_2231	2.468e-43	162.0	COG3568@1|root,COG3568@2|Bacteria,1ZV66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS3_k127_2780569_1	1192034.CAP_4364	5.238e-62	224.0	COG0477@1|root,COG2814@2|Bacteria,1N5ZF@1224|Proteobacteria,438JY@68525|delta/epsilon subdivisions,2X3UK@28221|Deltaproteobacteria,2YX51@29|Myxococcales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_2780569_0	309807.SRU_0542	1.073e-71	254.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_284509_2	882082.SaccyDRAFT_2363	5.035e-09	63.0	COG0662@1|root,COG0662@2|Bacteria,2IKY8@201174|Actinobacteria,4EC0T@85010|Pseudonocardiales	201174|Actinobacteria	G	domain-containing protein	sppH	-	-	ko:K14673	-	-	-	-	ko00000,ko01008	-	-	-	Cupin_2
GDHHQS3_k127_284509_0	861299.J421_1729	1.054e-190	622.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_284509_1	324925.Ppha_0265	6.428e-43	160.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS3_k127_284509_3	357808.RoseRS_3308	2.55e-08	57.0	COG2336@1|root,COG2336@2|Bacteria,2G9F5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM SpoVT AbrB domain protein	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
GDHHQS3_k127_2867175_6	1449976.KALB_3518	2.656e-07	58.0	COG0461@1|root,COG0461@2|Bacteria,2H5SI@201174|Actinobacteria,4EBR1@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_2867175_5	1265502.KB905938_gene2432	4.722e-10	64.0	2DT41@1|root,33IK2@2|Bacteria,1NNPM@1224|Proteobacteria,2W6H7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2867175_0	861299.J421_5977	1.333e-116	388.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS3_k127_2867175_4	518766.Rmar_1735	1.33e-52	196.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1FJUS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS3_k127_2867175_3	861299.J421_2739	3.343e-68	240.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	-	3.2.2.27	ko:K03648,ko:K21929	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
GDHHQS3_k127_2867175_2	861299.J421_4120	6.9e-74	256.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS3_k127_2867175_1	861299.J421_4121	1.81e-108	358.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS3_k127_2878887_23	153948.NAL212_2209	4.642e-45	173.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
GDHHQS3_k127_2878887_24	1123248.KB893370_gene5112	7.16e-32	136.0	COG2120@1|root,COG2120@2|Bacteria,4P6M2@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_2878887_0	861299.J421_6152	0.0	3279.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS3_k127_2878887_3	525897.Dbac_1184	2.416e-202	642.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
GDHHQS3_k127_2878887_19	379066.GAU_1134	1.058e-55	202.0	COG1878@1|root,COG1878@2|Bacteria,1ZU2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS3_k127_2878887_1	861299.J421_1532	6.931e-318	987.0	COG0021@1|root,COG0021@2|Bacteria,1ZTA2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GDHHQS3_k127_2878887_16	266117.Rxyl_1054	1.099e-60	218.0	COG0400@1|root,COG0400@2|Bacteria,2INMY@201174|Actinobacteria,4CTAJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	DLH
GDHHQS3_k127_2878887_8	251229.Chro_1450	5.052e-116	381.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
GDHHQS3_k127_2878887_14	861299.J421_1595	3.507e-64	230.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
GDHHQS3_k127_2878887_11	926550.CLDAP_34140	1.642e-92	332.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
GDHHQS3_k127_2878887_13	861299.J421_0442	1.342e-69	240.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2878887_25	861299.J421_0441	7.723e-25	119.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_2878887_6	861299.J421_1669	1.536e-145	466.0	COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_2878887_21	861299.J421_1705	1.219e-49	187.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2
GDHHQS3_k127_2878887_18	861299.J421_1707	7.627e-57	203.0	COG1514@1|root,COG1514@2|Bacteria,1ZTNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
GDHHQS3_k127_2878887_20	1379270.AUXF01000001_gene2184	1.713e-50	193.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS3_k127_2878887_22	1267533.KB906734_gene4053	1.487e-48	185.0	2EFRH@1|root,339HI@2|Bacteria,3Y7RW@57723|Acidobacteria,2JN1K@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2878887_2	502025.Hoch_5309	2.058e-255	797.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_2878887_30	240015.ACP_3398	1.753e-06	57.0	2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria,2JJW7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2878887_12	861299.J421_2327	1.227e-70	246.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
GDHHQS3_k127_2878887_9	861299.J421_5793	3.106e-115	381.0	COG1680@1|root,COG1680@2|Bacteria,1ZUWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_2878887_5	861299.J421_4258	1.895e-168	541.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS3_k127_2878887_7	1227739.Hsw_1849	1.457e-140	462.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47TTT@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_2878887_15	196367.JNFG01000007_gene6804	2.196e-61	220.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,2VKQ2@28216|Betaproteobacteria,1KFDF@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
GDHHQS3_k127_2878887_10	1265313.HRUBRA_02839	3.786e-101	350.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycine betaine	opuCC	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
GDHHQS3_k127_2878887_17	861299.J421_1866	2.02e-58	213.0	28P9J@1|root,2ZC30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2878887_4	379066.GAU_1432	2.542e-188	602.0	COG0531@1|root,COG0531@2|Bacteria,1ZSUB@142182|Gemmatimonadetes	2|Bacteria	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_2901485_2	1122604.JONR01000001_gene1860	1.082e-28	116.0	2E54V@1|root,32ZXS@2|Bacteria,1N6QG@1224|Proteobacteria,1SUWW@1236|Gammaproteobacteria,1X8X7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2901485_0	1123242.JH636436_gene366	2.833e-55	200.0	COG5649@1|root,COG5649@2|Bacteria,2IYNG@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_2901485_3	1122176.KB903537_gene1604	6.454e-27	117.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
GDHHQS3_k127_2901485_1	468059.AUHA01000002_gene1379	2.094e-38	153.0	COG0500@1|root,COG2226@2|Bacteria,4NNDT@976|Bacteroidetes,1IRYR@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_2966762_0	861299.J421_2605	2.199e-116	382.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GDHHQS3_k127_2966762_1	1379270.AUXF01000004_gene3229	3.395e-113	379.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_2968768_0	861299.J421_2428	2.733e-242	762.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GDHHQS3_k127_2968768_1	1379270.AUXF01000003_gene3372	3.556e-33	133.0	COG1188@1|root,COG1188@2|Bacteria,1ZTXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
GDHHQS3_k127_2968768_4	861299.J421_2918	1.143e-13	79.0	2FCTB@1|root,344W9@2|Bacteria,1ZU4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2968768_3	379066.GAU_0520	4.056e-26	119.0	COG0265@1|root,COG0265@2|Bacteria,1ZTV0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
GDHHQS3_k127_2968768_2	945713.IALB_0512	3.002e-29	123.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GDHHQS3_k127_3027920_1	865938.Weevi_0768	2.762e-08	63.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_3027920_0	526225.Gobs_2962	1.626e-91	313.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
GDHHQS3_k127_3052766_3	861299.J421_2968	1.107e-59	217.0	COG1947@1|root,COG1947@2|Bacteria,1ZTM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
GDHHQS3_k127_3052766_0	861299.J421_2969	9.782e-97	326.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_3052766_4	861299.J421_2970	1.748e-24	113.0	2CB0K@1|root,343GC@2|Bacteria,1ZU4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
GDHHQS3_k127_3052766_1	861299.J421_2971	1.259e-91	307.0	COG0854@1|root,COG0854@2|Bacteria,1ZSPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
GDHHQS3_k127_3052766_5	379066.GAU_1248	1.459e-23	106.0	28ZEQ@1|root,2ZM6A@2|Bacteria,1ZU2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3052766_2	379066.GAU_1249	1.484e-62	218.0	COG0346@1|root,COG0346@2|Bacteria,1ZTMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GDHHQS3_k127_3052766_6	379066.GAU_1250	1.05e-22	104.0	COG3118@1|root,COG3118@2|Bacteria,1ZTS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_3056892_1	292564.Cyagr_1917	3.917e-23	109.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,Peptidase_C13,Peptidase_C14
GDHHQS3_k127_3056892_0	330214.NIDE3501	4.287e-62	224.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
GDHHQS3_k127_3071937_2	626418.bglu_1g07830	7.974e-31	124.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VXF9@28216|Betaproteobacteria,1KAQV@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
GDHHQS3_k127_3071937_1	626418.bglu_1g07840	1.287e-131	426.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VII1@28216|Betaproteobacteria,1K2HH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to GP 17427840	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
GDHHQS3_k127_3071937_3	388051.AUFE01000098_gene3762	4.872e-05	46.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,1K6MM@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS3_k127_3071937_0	745310.G432_01310	7.693e-228	715.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2TRXQ@28211|Alphaproteobacteria,2K2VE@204457|Sphingomonadales	204457|Sphingomonadales	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS3_k127_3075274_1	379066.GAU_0476	1.129e-193	611.0	COG1249@1|root,COG1249@2|Bacteria,1ZTF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_3075274_10	158189.SpiBuddy_2575	8.175e-34	141.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS3_k127_3075274_6	1122605.KB893646_gene195	4.66e-71	253.0	2B33H@1|root,31VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3075274_5	1121904.ARBP01000017_gene5069	5.796e-84	289.0	2CK9T@1|root,2Z7W9@2|Bacteria,4NH9E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3075274_4	867903.ThesuDRAFT_01226	2.36e-102	338.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,3WD8B@538999|Clostridiales incertae sedis	186801|Clostridia	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
GDHHQS3_k127_3075274_0	319795.Dgeo_2522	8.169e-221	707.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_3075274_2	1232410.KI421412_gene169	3.294e-187	591.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_3075274_7	189753.AXAS01000024_gene569	1.073e-62	225.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2VGGI@28211|Alphaproteobacteria,3JRQ0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_3075274_8	56110.Oscil6304_5476	1.252e-47	177.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria,1HAYJ@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GDHHQS3_k127_3075274_3	404589.Anae109_0592	5.535e-164	520.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_3075274_9	861299.J421_0636	1.494e-43	160.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GDHHQS3_k127_3125948_2	1120950.KB892767_gene5169	5.513e-34	134.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DTC9@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_3125948_1	861299.J421_3680	2.802e-75	261.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
GDHHQS3_k127_3125948_0	861299.J421_0783	4.561e-121	402.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS3_k127_321856_1	861299.J421_4131	4.8e-24	103.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GDHHQS3_k127_321856_0	861299.J421_4089	1.938e-160	517.0	COG1680@1|root,COG1680@2|Bacteria,1ZUDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_321856_3	178306.PAE0993	2.125e-06	55.0	COG5550@1|root,arCOG03741@2157|Archaea	2157|Archaea	O	copper ion binding	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
GDHHQS3_k127_321856_2	401053.AciPR4_1493	5.7e-14	74.0	2C74X@1|root,3304C@2|Bacteria,3Y5TB@57723|Acidobacteria,2JK6Z@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_33508_0	861299.J421_2948	0.0	1130.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
GDHHQS3_k127_33508_3	861299.J421_2949	2.628e-46	171.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS3_k127_33508_2	379066.GAU_1203	3.884e-65	226.0	COG0359@1|root,COG0359@2|Bacteria,1ZTNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS3_k127_33508_1	861299.J421_2951	9.337e-70	248.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
GDHHQS3_k127_33508_5	379066.GAU_1205	2.543e-26	109.0	COG0238@1|root,COG0238@2|Bacteria,1ZU47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS3_k127_33508_4	1379270.AUXF01000005_gene514	2.761e-31	123.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS3_k127_336511_2	1313421.JHBV01000007_gene4227	4.341e-24	113.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
GDHHQS3_k127_336511_0	861299.J421_3960	8.203e-148	475.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_336511_1	29581.BW37_03287	4.156e-122	403.0	COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2VTBE@28216|Betaproteobacteria,475Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_336511_3	861299.J421_1752	9.275e-06	52.0	2DWGD@1|root,3407S@2|Bacteria,1ZV24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_3368400_0	1242864.D187_005776	3.651e-193	608.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3368400_1	1163409.UUA_06454	7.024e-57	201.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1X6M5@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_3368400_2	1535287.JP74_07995	8.862e-31	123.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,3N90Q@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
GDHHQS3_k127_3368400_3	1234364.AMSF01000015_gene3100	1.645e-11	68.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1X4FN@135614|Xanthomonadales	135614|Xanthomonadales	G	Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
GDHHQS3_k127_3370916_1	861299.J421_4368	2.822e-34	134.0	COG0607@1|root,COG0607@2|Bacteria,1ZTWY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_3370916_0	945713.IALB_1464	1.863e-49	187.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
GDHHQS3_k127_3370916_2	861299.J421_4367	1.675e-26	113.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_3384063_2	861299.J421_6240	1.606e-168	537.0	COG4888@1|root,COG4888@2|Bacteria,1ZUSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS3_k127_3384063_4	861299.J421_6242	4.013e-33	135.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
GDHHQS3_k127_3384063_1	1379270.AUXF01000003_gene3768	8.783e-273	856.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
GDHHQS3_k127_3384063_0	861299.J421_6243	0.0	1382.0	COG4888@1|root,COG4888@2|Bacteria,1ZURG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS3_k127_3384063_5	861299.J421_1631	6.734e-25	107.0	COG4095@1|root,COG4095@2|Bacteria	2|Bacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
GDHHQS3_k127_3384063_3	234267.Acid_4350	2.238e-97	327.0	COG0560@1|root,COG0560@2|Bacteria,3Y6IV@57723|Acidobacteria	57723|Acidobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS3_k127_3386252_6	861299.J421_3236	4.209e-39	150.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS3_k127_3386252_1	379066.GAU_1603	2.664e-121	399.0	COG0240@1|root,COG0240@2|Bacteria,1ZTFK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS3_k127_3386252_5	1379270.AUXF01000006_gene283	2.498e-47	174.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS3_k127_3386252_7	935567.JAES01000007_gene1848	5.308e-33	136.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,1S39Y@1236|Gammaproteobacteria,1XCJR@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_3386252_0	861299.J421_3239	3.201e-127	413.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS3_k127_3386252_3	861299.J421_3240	3.904e-97	323.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS3_k127_3386252_9	1382356.JQMP01000003_gene2541	5.14e-13	78.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi,27YMW@189775|Thermomicrobia	189775|Thermomicrobia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS3_k127_3386252_8	1379270.AUXF01000006_gene278	9.818e-31	131.0	COG2976@1|root,COG2976@2|Bacteria,1ZTZV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS3_k127_3386252_4	861299.J421_3244	3.444e-86	294.0	COG0253@1|root,COG0253@2|Bacteria,1ZU42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS3_k127_3386252_2	1379270.AUXF01000006_gene276	1.552e-112	367.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS3_k127_3392234_2	861299.J421_3101	6.081e-210	659.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_3392234_3	861299.J421_3104	7.579e-192	620.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
GDHHQS3_k127_3392234_4	1379270.AUXF01000005_gene710	2.435e-169	541.0	COG0158@1|root,COG0158@2|Bacteria,1ZTAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
GDHHQS3_k127_3392234_0	861299.J421_3107	2.359e-254	793.0	COG1884@1|root,COG1884@2|Bacteria,1ZT5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_3392234_7	861299.J421_3109	7.368e-19	92.0	COG2331@1|root,COG2331@2|Bacteria,1ZU2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3392234_1	379066.GAU_1467	3.039e-246	771.0	COG0018@1|root,COG0018@2|Bacteria,1ZT6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS3_k127_3392234_5	1379270.AUXF01000005_gene720	9.171e-149	475.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS3_k127_3397856_0	379066.GAU_2427	2.697e-180	568.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS3_k127_3397856_4	861299.J421_3872	1.266e-56	203.0	COG1490@1|root,COG1490@2|Bacteria,1ZTVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS3_k127_3397856_3	861299.J421_3871	8.211e-69	239.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS3_k127_3397856_6	670487.Ocepr_0499	1.095e-24	111.0	COG1051@1|root,COG1051@2|Bacteria,1WNG1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_3397856_1	861299.J421_3870	2.877e-152	488.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS3_k127_3397856_5	861299.J421_3869	1.836e-43	168.0	COG3642@1|root,COG3642@2|Bacteria,1ZTTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
GDHHQS3_k127_3397856_2	861299.J421_3867	6.879e-75	254.0	COG0147@1|root,COG0147@2|Bacteria,1ZSPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS3_k127_3404092_0	861299.J421_2348	6.155e-223	703.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1ZSQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS3_k127_3404092_1	861299.J421_2349	2.557e-100	331.0	COG0493@1|root,COG0493@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes	2|Bacteria	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
GDHHQS3_k127_3415900_4	509190.Cseg_0880	7.498e-18	93.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
GDHHQS3_k127_3415900_3	378806.STAUR_7458	5.159e-45	166.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,43AM1@68525|delta/epsilon subdivisions,2X616@28221|Deltaproteobacteria,2Z388@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS3_k127_3415900_0	290397.Adeh_3813	2.511e-76	259.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_3415900_5	1379270.AUXF01000003_gene3808	1.483e-15	83.0	2ENGP@1|root,33G46@2|Bacteria,1ZU71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS3_k127_3426865_2	1123060.JONP01000142_gene5228	6.911e-12	67.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,2JTS2@204441|Rhodospirillales	204441|Rhodospirillales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS3_k127_3426865_0	316273.XCV4228	2.027e-28	124.0	COG1266@1|root,COG1266@2|Bacteria,1QVRB@1224|Proteobacteria,1ST8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS3_k127_3426865_1	1411123.JQNH01000001_gene376	2.447e-17	83.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3444294_4	861299.J421_4331	9.458e-127	415.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS3_k127_3444294_7	861299.J421_4333	6.749e-37	152.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GDHHQS3_k127_3444294_5	861299.J421_4334	1.218e-65	238.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_3444294_8	861299.J421_4335	8.487e-32	136.0	2F1E3@1|root,33UEU@2|Bacteria,1ZTQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3444294_3	861299.J421_4336	6.876e-136	449.0	COG1306@1|root,COG1306@2|Bacteria	2|Bacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS3_k127_3444294_13	1489678.RDMS_09620	1.757e-09	61.0	COG2608@1|root,COG2608@2|Bacteria,1WKNR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
GDHHQS3_k127_3444294_1	861299.J421_4346	3.866e-180	577.0	COG2239@1|root,COG2239@2|Bacteria,1ZT3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_3444294_2	861299.J421_1756	1.403e-164	533.0	COG0624@1|root,COG0624@2|Bacteria,1ZUA4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_3444294_10	365046.Rta_16920	1.845e-19	94.0	2AWDT@1|root,32ZDK@2|Bacteria,1NE1B@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
GDHHQS3_k127_3444294_0	404589.Anae109_2419	1.415e-205	662.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_3444294_6	861299.J421_4349	2.515e-48	181.0	COG3346@1|root,COG3346@2|Bacteria,1ZTTS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SURF1 family	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
GDHHQS3_k127_3444294_9	1116472.MGMO_55c00340	5.822e-20	94.0	2B0DW@1|root,31SR8@2|Bacteria,1RHKN@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
GDHHQS3_k127_3444294_12	204669.Acid345_1150	3.262e-15	78.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3463763_0	349521.HCH_02499	9.255e-50	186.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales	135619|Oceanospirillales	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_3463763_1	909663.KI867150_gene1782	3.083e-16	81.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria,43B9P@68525|delta/epsilon subdivisions,2X6NT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3470255_1	880072.Desac_0492	6.465e-57	204.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
GDHHQS3_k127_3470255_0	861299.J421_2546	8.19e-80	276.0	COG1597@1|root,COG1597@2|Bacteria,1ZU66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
GDHHQS3_k127_3470255_2	404589.Anae109_3731	1.483e-53	205.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
GDHHQS3_k127_3484002_5	639283.Snov_0827	2.453e-20	91.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TUNG@28211|Alphaproteobacteria,3F1TP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	MA20_22750	-	-	-	-	-	-	-	-	-	-	-	DsbD
GDHHQS3_k127_3484002_3	398527.Bphyt_4138	3.445e-98	322.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VKRT@28216|Betaproteobacteria,1K4CU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS3_k127_3484002_6	1123256.KB907925_gene1491	3.181e-10	69.0	COG3453@1|root,COG3453@2|Bacteria,1N919@1224|Proteobacteria,1SEMT@1236|Gammaproteobacteria,1X8A2@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
GDHHQS3_k127_3484002_1	1132509.C447_09085	1.672e-137	445.0	COG0451@1|root,arCOG03019@2157|Archaea,2XVZH@28890|Euryarchaeota,23U95@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_3484002_0	1379270.AUXF01000005_gene351	2.51e-185	591.0	COG1228@1|root,COG1228@2|Bacteria,1ZSME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_3484002_2	1123073.KB899241_gene2558	7.675e-114	378.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,1RNKY@1236|Gammaproteobacteria,1X4MJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Oxidoreductase	ydgJ	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_3484002_4	1246484.D479_10991	2.104e-21	96.0	COG0671@1|root,COG0671@2|Bacteria,1UYGU@1239|Firmicutes,4HB7A@91061|Bacilli,3NDXV@45667|Halobacillus	91061|Bacilli	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS3_k127_3500067_2	234267.Acid_3757	4.306e-52	191.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K03086,ko:K06867,ko:K06886	-	-	-	-	ko00000,ko03021	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
GDHHQS3_k127_3500067_3	1267535.KB906767_gene4818	6.636e-25	108.0	COG3801@1|root,COG3801@2|Bacteria,3Y89M@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS3_k127_3500067_0	1267535.KB906767_gene5245	1.371e-147	507.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_3500067_1	344747.PM8797T_20763	1.215e-116	396.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
GDHHQS3_k127_3500067_4	485913.Krac_5098	4.107e-21	94.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_3500437_1	861299.J421_2566	1.266e-107	357.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS3_k127_3500437_3	1382358.JHVN01000015_gene655	5.531e-33	139.0	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,21WTY@150247|Anoxybacillus	91061|Bacilli	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3,5.3.99.10	ko:K00788,ko:K10810	ko00730,ko01100,map00730,map01100	M00127	R03223,R09977,R10712	RC00224,RC02766,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	TMP-TENI
GDHHQS3_k127_3500437_4	882.DVU_2095	6.833e-07	60.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2WSM2@28221|Deltaproteobacteria,2MDTU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_3500437_2	243231.GSU0588	6.491e-92	309.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS3_k127_3500437_0	1379270.AUXF01000004_gene3261	5.779e-143	468.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
GDHHQS3_k127_3507953_0	1266914.ATUK01000014_gene2025	7.821e-99	327.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS3_k127_3507953_1	640081.Dsui_1450	1.466e-98	330.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KUQG@206389|Rhodocyclales	206389|Rhodocyclales	T	Serine/threonine phosphatases, family 2C, catalytic domain	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_3507953_2	1000565.METUNv1_02453	1.197e-37	145.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_3514644_2	1121918.ARWE01000001_gene3199	5.522e-59	214.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_3514644_4	1121918.ARWE01000001_gene3197	1.558e-30	130.0	COG2204@1|root,COG4567@1|root,COG2204@2|Bacteria,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
GDHHQS3_k127_3514644_0	1123508.JH636440_gene2646	2.215e-140	467.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_3514644_5	1408418.JNJH01000043_gene3127	1.602e-08	67.0	2FITE@1|root,34AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3514644_1	861299.J421_0341	9.113e-64	231.0	COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_3514644_3	861299.J421_1397	6.41e-41	171.0	COG0642@1|root,COG2205@2|Bacteria,1ZUX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_3529285_2	1128421.JAGA01000002_gene905	1.519e-38	151.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
GDHHQS3_k127_3529285_1	861299.J421_0149	9.958e-79	269.0	COG0122@1|root,COG0122@2|Bacteria,1ZTST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS3_k127_3529285_0	1382306.JNIM01000001_gene1966	3.708e-173	556.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS3_k127_3555948_4	497965.Cyan7822_3191	2.533e-48	176.0	COG1028@1|root,COG1028@2|Bacteria,1G4JP@1117|Cyanobacteria,3KH1N@43988|Cyanothece	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_3555948_3	861299.J421_5909	5.057e-57	224.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5909|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3555948_2	426117.M446_0742	6.562e-63	227.0	COG0063@1|root,COG0063@2|Bacteria,1RDYQ@1224|Proteobacteria,2U7VX@28211|Alphaproteobacteria,1JTN0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
GDHHQS3_k127_3555948_1	1123060.JONP01000014_gene4167	2.181e-89	303.0	COG0406@1|root,COG0406@2|Bacteria,1RAPQ@1224|Proteobacteria,2U0U1@28211|Alphaproteobacteria,2JVC1@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_3555948_0	861299.J421_2320	2.193e-98	341.0	COG4783@1|root,COG4783@2|Bacteria,1ZT4T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3557851_2	518766.Rmar_1738	1.324e-58	206.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1FJXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GMC oxidoreductase	betA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_3557851_3	1121920.AUAU01000006_gene301	2.319e-49	182.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3557851_0	221288.JH992901_gene2013	1.278e-156	509.0	COG0477@1|root,COG0477@2|Bacteria,1G155@1117|Cyanobacteria,1JK0M@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3557851_4	1123393.KB891327_gene316	4.178e-17	81.0	2E5C5@1|root,33046@2|Bacteria,1NNAA@1224|Proteobacteria,2W6KD@28216|Betaproteobacteria,1KT4P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS3_k127_3557851_1	1267534.KB906755_gene4573	1.41e-62	220.0	COG0842@1|root,COG0842@2|Bacteria,3Y6GQ@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_3572954_1	1123008.KB905693_gene1405	2.355e-72	252.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia,22WIN@171551|Porphyromonadaceae	976|Bacteroidetes	G	F5 8 type C domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
GDHHQS3_k127_3572954_2	264198.Reut_B4583	1.2e-55	199.0	COG3797@1|root,COG3797@2|Bacteria,1N1TC@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_3572954_6	1379270.AUXF01000005_gene618	5.403e-05	47.0	COG4758@1|root,COG4758@2|Bacteria,1ZU48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
GDHHQS3_k127_3572954_5	306281.AJLK01000116_gene4252	1.264e-14	80.0	COG1943@1|root,COG1943@2|Bacteria,1G7D3@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS3_k127_3572954_4	1288494.EBAPG3_4640	1.722e-36	141.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2WA6I@28216|Betaproteobacteria,3749W@32003|Nitrosomonadales	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_3572954_3	1278073.MYSTI_05295	1.508e-40	153.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_3572954_0	1151127.KB906330_gene2922	8.484e-107	361.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,1YM35@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,TPR_2
GDHHQS3_k127_3579274_1	861299.J421_0447	2.068e-132	426.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_3579274_0	379066.GAU_0200	3.02e-134	452.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1ZTAG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS3_k127_3579274_2	379066.GAU_0199	4.281e-121	400.0	COG3437@1|root,COG3437@2|Bacteria,1ZTD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
GDHHQS3_k127_3595855_3	379066.GAU_1450	2.103e-48	174.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
GDHHQS3_k127_3595855_4	477974.Daud_2046	1.121e-34	138.0	COG0295@1|root,COG0319@1|root,COG0295@2|Bacteria,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
GDHHQS3_k127_3595855_1	379066.GAU_1452	1.047e-64	239.0	2F0K0@1|root,33TNP@2|Bacteria,1ZTJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3595855_2	861299.J421_3097	1.876e-63	233.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3595855_0	861299.J421_3098	1.018e-165	529.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_3098|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3595855_5	861299.J421_3101	9.536e-11	62.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_36128_2	861299.J421_6223	9.233e-43	160.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_36128_1	861299.J421_0340	1.63e-77	268.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
GDHHQS3_k127_36128_3	861299.J421_3379	2.551e-24	106.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
GDHHQS3_k127_36128_0	1452718.JBOY01000054_gene1977	1.689e-157	516.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
GDHHQS3_k127_3662274_1	861299.J421_1774	1.273e-73	254.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	2|Bacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_3662274_0	861299.J421_1309	1.156e-109	374.0	2C9ZY@1|root,33R5C@2|Bacteria,1ZSVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3689234_1	1379270.AUXF01000003_gene3556	4.986e-152	484.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_3689234_0	861299.J421_2683	4.826e-160	524.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_3689234_2	861299.J421_1574	6.602e-127	425.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS3_k127_3689234_4	880073.Calab_1265	3.709e-82	286.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_3689234_7	1463864.JOGO01000026_gene2756	5.476e-11	74.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
GDHHQS3_k127_3689234_9	379066.GAU_1034	2.933e-06	58.0	2C5K1@1|root,2ZR6Y@2|Bacteria,1ZV9C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3689234_6	861299.J421_3723	1.538e-22	109.0	COG0457@1|root,COG2206@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE6_C,DICT,GerE,HD,HD_5
GDHHQS3_k127_3689234_8	861299.J421_2126	8.084e-07	59.0	2C5K1@1|root,2ZR6Y@2|Bacteria,1ZV9C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3689234_3	861299.J421_1574	6.849e-121	411.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS3_k127_3689234_5	861299.J421_1574	5.334e-30	132.0	COG0457@1|root,COG2199@1|root,COG2206@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1ZU95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,HD,TPR_12
GDHHQS3_k127_3689234_10	379066.GAU_1034	7.344e-06	53.0	2C5K1@1|root,2ZR6Y@2|Bacteria,1ZV9C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705741_1	234267.Acid_7716	5.125e-54	196.0	COG3386@1|root,COG3386@2|Bacteria,3Y5XH@57723|Acidobacteria	57723|Acidobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS3_k127_3705741_2	1242864.D187_009177	0.0004057	51.0	COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494
GDHHQS3_k127_3705741_0	443143.GM18_2076	0.0	1107.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43U5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
GDHHQS3_k127_3729885_13	861299.J421_2063	1.208e-43	162.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS3_k127_3729885_21	682795.AciX8_4517	6.267e-06	57.0	COG1629@1|root,COG1629@2|Bacteria,3Y9BW@57723|Acidobacteria,2JP0H@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
GDHHQS3_k127_3729885_14	861299.J421_2061	9.463e-41	160.0	2F7IP@1|root,33ZZA@2|Bacteria,1ZTTA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3729885_1	861299.J421_2060	1.347e-251	794.0	COG1012@1|root,COG1012@2|Bacteria,1ZSRK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS3_k127_3729885_3	861299.J421_2044	4.131e-189	616.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3729885_16	861299.J421_3991	5.881e-35	143.0	29F5I@1|root,30238@2|Bacteria,1ZU4C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3729885_8	204669.Acid345_0284	2.994e-85	289.0	COG1131@1|root,COG1131@2|Bacteria,3Y4CW@57723|Acidobacteria,2JMQR@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_3729885_6	1254432.SCE1572_33565	7.468e-91	311.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GDHHQS3_k127_3729885_15	861299.J421_3990	1.425e-37	146.0	COG1186@1|root,COG1186@2|Bacteria,1ZTZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GDHHQS3_k127_3729885_7	861299.J421_4544	2.105e-87	299.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3729885_2	401053.AciPR4_1363	5.754e-209	657.0	COG0666@1|root,COG0666@2|Bacteria,3Y3EY@57723|Acidobacteria	57723|Acidobacteria	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3729885_11	234267.Acid_6140	1.006e-67	237.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_25
GDHHQS3_k127_3729885_10	469383.Cwoe_1767	5.177e-70	247.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS3_k127_3729885_9	1234364.AMSF01000027_gene3499	1.396e-70	247.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,1S3D2@1236|Gammaproteobacteria,1X3MK@135614|Xanthomonadales	135614|Xanthomonadales	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
GDHHQS3_k127_3729885_0	861299.J421_2017	0.0	1316.0	COG0841@1|root,COG0841@2|Bacteria,1ZTEK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS3_k127_3729885_5	861299.J421_2016	4.112e-108	363.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS3_k127_3729885_4	861299.J421_2015	8.279e-116	392.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_3729885_12	379066.GAU_3093	1.005e-43	166.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_3729885_20	357808.RoseRS_1500	1.491e-23	115.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi,377H2@32061|Chloroflexia	32061|Chloroflexia	P	copper resistance D domain protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GDHHQS3_k127_3729885_19	1382304.JNIL01000001_gene50	7.049e-29	125.0	COG4549@1|root,COG4549@2|Bacteria,1V509@1239|Firmicutes,4HH2V@91061|Bacilli,279V7@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unkown function (DUF1775)	ycnI	-	-	-	-	-	-	-	-	-	-	-	DUF1775
GDHHQS3_k127_3729885_17	861299.J421_2255	8.348e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,1ZV07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS3_k127_3729885_18	861299.J421_2256	5.84e-29	119.0	COG0500@1|root,COG2226@2|Bacteria,1ZSM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS3_k127_3732597_4	861299.J421_0464	2.604e-194	619.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS3_k127_3732597_8	861299.J421_0472	3.427e-150	483.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3732597_15	861299.J421_0497	2.149e-85	289.0	2EVAX@1|root,33NRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3732597_25	861299.J421_0499	4.139e-31	122.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_3732597_11	861299.J421_0599	7.047e-119	390.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS3_k127_3732597_5	153721.MYP_1412	4.705e-187	618.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS3_k127_3732597_16	861299.J421_0502	6.143e-73	252.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS3_k127_3732597_6	1379270.AUXF01000004_gene2878	6.662e-165	541.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_3732597_22	1379270.AUXF01000002_gene1441	2.387e-42	156.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
GDHHQS3_k127_3732597_9	861299.J421_0504	2.298e-145	462.0	COG1398@1|root,COG1398@2|Bacteria,1ZT9N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	-
GDHHQS3_k127_3732597_12	861299.J421_0507	1.367e-111	372.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
GDHHQS3_k127_3732597_13	861299.J421_0510	8.308e-107	361.0	COG2220@1|root,COG2220@2|Bacteria,1ZUY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS3_k127_3732597_19	861299.J421_0517	1.595e-59	216.0	COG1647@1|root,COG1647@2|Bacteria,1ZTVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GDHHQS3_k127_3732597_18	861299.J421_0519	1.863e-62	224.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	MA20_24885	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K07001,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Acetyltransf_3,cNMP_binding
GDHHQS3_k127_3732597_0	861299.J421_1389	3.747e-282	884.0	COG2234@1|root,COG2234@2|Bacteria,1ZSQ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nicastrin	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS3_k127_3732597_21	379066.GAU_0162	2.385e-43	166.0	2CM4I@1|root,340QM@2|Bacteria,1ZTV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3732597_7	1379270.AUXF01000002_gene1431	1.585e-159	516.0	COG4992@1|root,COG4992@2|Bacteria,1ZTEJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_3732597_17	1379270.AUXF01000002_gene1430	1.055e-69	244.0	COG0548@1|root,COG0548@2|Bacteria,1ZTJI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_3732597_10	861299.J421_1328	1.052e-120	395.0	COG0002@1|root,COG0002@2|Bacteria,1ZSV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_3732597_20	861299.J421_1325	2.46e-54	195.0	COG1438@1|root,COG1438@2|Bacteria,1ZU02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
GDHHQS3_k127_3732597_1	861299.J421_1323	2.059e-214	671.0	COG0137@1|root,COG0137@2|Bacteria,1ZTYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS3_k127_3732597_2	861299.J421_1322	1.805e-213	672.0	COG0165@1|root,COG0165@2|Bacteria,1ZSM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS3_k127_3732597_23	861299.J421_1300	4.449e-36	138.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_3732597_24	666681.M301_1562	2.325e-35	140.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria,2KMYD@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3732597_3	861299.J421_1297	3.674e-200	631.0	COG0821@1|root,COG0821@2|Bacteria,1ZST3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS3_k127_3732597_14	1379270.AUXF01000002_gene1414	6.05e-88	295.0	COG0317@1|root,COG0317@2|Bacteria,1ZTKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
GDHHQS3_k127_3732597_29	1192034.CAP_8913	1.226e-17	83.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,42WFV@68525|delta/epsilon subdivisions,2WS6B@28221|Deltaproteobacteria,2YUWV@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
GDHHQS3_k127_3741655_3	536227.CcarbDRAFT_2579	6.363e-14	78.0	COG2815@1|root,COG2815@2|Bacteria,1UJ16@1239|Firmicutes,25EU0@186801|Clostridia	186801|Clostridia	S	PASTA domain	-	-	-	-	-	-	-	-	-	-	-	-	PASTA
GDHHQS3_k127_3741655_1	861299.J421_2563	2.575e-88	305.0	COG0036@1|root,COG0036@2|Bacteria,1ZSP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_3741655_2	379066.GAU_0620	8.968e-58	206.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_3741655_0	861299.J421_2560	5.54e-97	319.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_3749808_7	32057.KB217478_gene7415	1.034e-25	118.0	COG0500@1|root,COG0500@2|Bacteria,1G4D6@1117|Cyanobacteria,1HNTN@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
GDHHQS3_k127_3749808_4	861299.J421_2402	1.708e-152	492.0	COG4299@1|root,COG4299@2|Bacteria,1ZT4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
GDHHQS3_k127_3749808_1	861299.J421_3607	1.726e-258	811.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
GDHHQS3_k127_3749808_3	1045855.DSC_13360	5.406e-182	583.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RRY3@1236|Gammaproteobacteria,1XBYN@135614|Xanthomonadales	135614|Xanthomonadales	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
GDHHQS3_k127_3749808_6	861299.J421_6332	2.58e-135	443.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_3749808_5	861299.J421_3604	9.205e-139	462.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_3749808_0	468059.AUHA01000002_gene533	0.0	1368.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IPAN@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_3749808_2	468059.AUHA01000002_gene532	2.087e-215	681.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,1IP72@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
GDHHQS3_k127_3755682_0	861299.J421_3971	0.0	1177.0	COG0550@1|root,COG0550@2|Bacteria,1ZTA9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS3_k127_3755682_1	1379270.AUXF01000003_gene3404	4.403e-198	626.0	COG1206@1|root,COG1206@2|Bacteria,1ZTB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	gid	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS3_k127_3755682_2	861299.J421_3967	6.443e-135	438.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_3764955_1	234267.Acid_4748	6.302e-76	271.0	COG1858@1|root,COG1858@2|Bacteria,3Y7FY@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
GDHHQS3_k127_3764955_0	234267.Acid_5940	1.457e-202	664.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_3764955_2	379066.GAU_2812	8.162e-66	237.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015,ko:K06867	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Ank,Ank_2,Ank_4,Prenyltrans,SQHop_cyclase_C
GDHHQS3_k127_3764955_4	118168.MC7420_7975	2.198e-26	122.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
GDHHQS3_k127_3764955_3	234267.Acid_7677	6.791e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS3_k127_3769826_0	861299.J421_2575	1.564e-81	274.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS3_k127_3781086_6	861299.J421_2812	1.129e-127	421.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
GDHHQS3_k127_3781086_1	379066.GAU_0909	6.315e-233	726.0	COG0423@1|root,COG0423@2|Bacteria,1ZT4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
GDHHQS3_k127_3781086_4	861299.J421_2808	2.584e-135	439.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GDHHQS3_k127_3781086_2	861299.J421_2807	1.44e-224	702.0	COG0104@1|root,COG0104@2|Bacteria,1ZSNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS3_k127_3781086_0	861299.J421_0935	2.571e-242	770.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_3781086_12	861299.J421_0936	7.997e-36	139.0	arCOG03092@1|root,32YMQ@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS3_k127_3781086_14	861299.J421_0937	3.221e-32	128.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS3_k127_3781086_15	861299.J421_0938	1.834e-30	131.0	arCOG06390@1|root,330IR@2|Bacteria	2|Bacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle,GvpK
GDHHQS3_k127_3781086_16	1121422.AUMW01000016_gene2089	2.66e-05	55.0	2DJCY@1|root,305NK@2|Bacteria,1TYFT@1239|Firmicutes,256D7@186801|Clostridia,266HZ@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
GDHHQS3_k127_3781086_9	861299.J421_0941	8.089e-64	228.0	2C8AD@1|root,32RKP@2|Bacteria	2|Bacteria	S	Gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
GDHHQS3_k127_3781086_5	861299.J421_0944	3.389e-132	425.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS3_k127_3781086_11	379066.GAU_0906	2.136e-41	158.0	COG2839@1|root,COG2839@2|Bacteria,1ZUVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GDHHQS3_k127_3781086_3	861299.J421_2799	1.273e-155	497.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS3_k127_3781086_8	557598.LHK_00343	3.87e-67	241.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KQHE@206351|Neisseriales	206351|Neisseriales	G	Psort location Cytoplasmic, score 8.96	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS3_k127_3781086_7	861299.J421_2797	8.997e-74	250.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,1ZT04@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS3_k127_3784681_0	1122138.AQUZ01000019_gene8188	8.308e-18	87.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_3785709_1	861299.J421_0900	1.13e-90	304.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS3_k127_3785709_0	861299.J421_1629	2.03e-120	393.0	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GDHHQS3_k127_3814106_2	649747.HMPREF0083_01283	1.538e-141	459.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,26QU4@186822|Paenibacillaceae	91061|Bacilli	EG	Gluconate	gntP	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
GDHHQS3_k127_3814106_9	296591.Bpro_3525	1.701e-54	201.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,2VSY0@28216|Betaproteobacteria,4AEM1@80864|Comamonadaceae	28216|Betaproteobacteria	F	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,SKI
GDHHQS3_k127_3814106_8	861299.J421_3139	4.421e-64	224.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
GDHHQS3_k127_3814106_0	861299.J421_3137	0.0	1320.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_3814106_10	1379270.AUXF01000005_gene746	1.005e-46	173.0	COG2866@1|root,COG2866@2|Bacteria,1ZTUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3814106_3	1121468.AUBR01000016_gene2302	1.452e-110	381.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,42F9D@68295|Thermoanaerobacterales	186801|Clostridia	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS3_k127_3814106_6	861299.J421_3135	1.421e-83	284.0	COG1381@1|root,COG1381@2|Bacteria,1ZTHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS3_k127_3814106_1	861299.J421_3134	4.704e-144	481.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_3814106_5	861299.J421_3133	6.207e-90	308.0	COG1120@1|root,COG1120@2|Bacteria,1ZTB9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS3_k127_3814106_4	861299.J421_3132	3.714e-106	354.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS3_k127_3814106_7	861299.J421_3131	1.337e-80	278.0	COG0614@1|root,COG0614@2|Bacteria,1ZTIM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS3_k127_3823439_2	1128421.JAGA01000002_gene1191	1.157e-81	284.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS3_k127_3823439_3	861299.J421_0915	2.008e-79	284.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_3823439_1	1379270.AUXF01000002_gene1172	4.089e-120	404.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_3823439_0	861299.J421_1981	1.751e-143	465.0	COG0577@1|root,COG0577@2|Bacteria,1ZSUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3823439_4	861299.J421_1982	3.187e-63	231.0	COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GDHHQS3_k127_3856873_5	378806.STAUR_1879	9.461e-16	80.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
GDHHQS3_k127_3856873_0	945713.IALB_3087	1.121e-125	413.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
GDHHQS3_k127_3856873_3	1191523.MROS_1828	1.094e-49	190.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_3856873_2	1232410.KI421421_gene3684	1.38e-107	361.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_3856873_1	379066.GAU_0458	2.121e-124	402.0	COG1351@1|root,COG1351@2|Bacteria,1ZTEP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
GDHHQS3_k127_3856873_4	861299.J421_2362	3.692e-22	97.0	COG0277@1|root,COG0277@2|Bacteria,1ZTB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_386223_0	1183438.GKIL_0692	0.0	1262.0	COG1002@1|root,COG1002@2|Bacteria,1G393@1117|Cyanobacteria	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
GDHHQS3_k127_386223_2	478741.JAFS01000001_gene1317	8.431e-15	82.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_386223_1	478741.JAFS01000001_gene1316	1.753e-106	359.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
GDHHQS3_k127_3885859_0	379066.GAU_1663	6.774e-100	328.0	COG0717@1|root,COG0717@2|Bacteria,1ZSN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS3_k127_3885859_1	861299.J421_1389	2.698e-65	231.0	COG2234@1|root,COG2234@2|Bacteria,1ZSQ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nicastrin	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS3_k127_3900167_0	861299.J421_6223	7.144e-224	723.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3900167_2	1267533.KB906740_gene377	1.418e-53	191.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_3900167_5	379066.GAU_1351	8.228e-22	111.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_3900167_1	861299.J421_4246	2.051e-170	549.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	nueM	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
GDHHQS3_k127_3900167_3	1125863.JAFN01000001_gene3444	4.43e-47	184.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42Q41@68525|delta/epsilon subdivisions,2WK4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_3900167_4	861299.J421_2405	2.202e-46	188.0	COG0840@1|root,COG0840@2|Bacteria,1ZSWC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
GDHHQS3_k127_3900167_6	1379270.AUXF01000001_gene2752	2.356e-14	79.0	COG0603@1|root,COG0603@2|Bacteria,1ZT7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS3_k127_3919965_1	1396141.BATP01000044_gene1489	9.083e-143	456.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_3919965_2	1396141.BATP01000044_gene1487	2.487e-109	363.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS3_k127_3919965_0	861299.J421_1729	3.401e-155	518.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_3920944_11	861299.J421_3164	1.044e-88	297.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS3_k127_3920944_15	1379270.AUXF01000005_gene789	1.327e-42	159.0	COG0234@1|root,COG0234@2|Bacteria,1ZTZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS3_k127_3920944_13	767817.Desgi_0313	5.118e-57	211.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS3_k127_3920944_12	861299.J421_3159	9.178e-73	254.0	COG0340@1|root,COG0340@2|Bacteria,1ZTQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_3920944_8	379066.GAU_1533	4.676e-94	322.0	COG1968@1|root,COG1968@2|Bacteria,1ZU3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_3920944_1	861299.J421_3157	3.135e-167	535.0	COG0438@1|root,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_3920944_6	861299.J421_3156	4.532e-100	334.0	COG0324@1|root,COG0324@2|Bacteria,1ZTBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS3_k127_3920944_0	861299.J421_3155	3.399e-230	728.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS3_k127_3920944_3	861299.J421_3153	1.905e-146	487.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS3_k127_3920944_5	861299.J421_1138	1.506e-124	408.0	COG2304@1|root,COG2304@2|Bacteria,1ZSVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1194)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS3_k127_3920944_14	379066.GAU_1526	2.376e-47	183.0	29X7F@1|root,30IWP@2|Bacteria,1ZTUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3920944_4	861299.J421_3151	1.211e-131	427.0	COG1721@1|root,COG1721@2|Bacteria,1ZSKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_3920944_2	861299.J421_3150	1.226e-161	514.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_3920944_9	861299.J421_3149	4.804e-93	321.0	COG1187@1|root,COG1187@2|Bacteria,1ZT5B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_3920944_16	1536774.H70357_23930	5.83e-30	126.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,26SV4@186822|Paenibacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS3_k127_3920944_7	1379270.AUXF01000005_gene775	1.4e-95	325.0	COG1354@1|root,COG1354@2|Bacteria,1ZT1G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS3_k127_3920944_10	379066.GAU_1520	1.57e-92	310.0	COG1994@1|root,COG1994@2|Bacteria,1ZTIB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS3_k127_3920944_17	861299.J421_3145	2.734e-20	94.0	COG0268@1|root,COG0268@2|Bacteria,1ZU6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS3_k127_3920944_18	861299.J421_3144	3.783e-14	82.0	COG1196@1|root,COG1196@2|Bacteria,1ZU4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3930170_1	861299.J421_4481	1.211e-121	395.0	COG0501@1|root,COG0501@2|Bacteria,1ZSNK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS3_k127_3930170_2	861299.J421_4223	1.326e-110	373.0	COG0531@1|root,COG0531@2|Bacteria,1ZSZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_3930170_0	504728.K649_03245	1.062e-127	416.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_3946812_2	583355.Caka_1913	1e-30	136.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_3946812_0	1121918.ARWE01000001_gene245	1.403e-140	483.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,43TYD@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
GDHHQS3_k127_3946812_1	583355.Caka_1913	7.76e-55	198.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_3946812_3	4113.PGSC0003DMT400052301	2.493e-07	52.0	2E4EA@1|root,2S5QZ@2759|Eukaryota,37X8Y@33090|Viridiplantae,3GKGJ@35493|Streptophyta,44UAV@71274|asterids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_399507_1	861299.J421_3577	3.197e-104	340.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS3_k127_399507_5	1379270.AUXF01000003_gene3881	4.671e-62	219.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS3_k127_399507_4	1379270.AUXF01000003_gene3880	2.532e-62	217.0	COG0099@1|root,COG0099@2|Bacteria,1ZTNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS3_k127_399507_7	379066.GAU_1977	3.261e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS3_k127_399507_3	1379270.AUXF01000003_gene3879	5.289e-69	242.0	COG0284@1|root,COG0284@2|Bacteria,1ZTQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS3_k127_399507_0	379066.GAU_1979	5.538e-105	350.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_399507_2	1379270.AUXF01000003_gene3876	2.933e-98	336.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS3_k127_399507_6	861299.J421_3584	5.06e-43	159.0	COG0691@1|root,COG0691@2|Bacteria,1ZTQN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS3_k127_4034109_2	857087.Metme_4403	2.439e-07	53.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
GDHHQS3_k127_4034109_1	379066.GAU_3341	4.506e-52	189.0	2ECKJ@1|root,33KDJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4034109_0	296591.Bpro_1369	1.889e-197	628.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VJHX@28216|Betaproteobacteria,4ACRX@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
GDHHQS3_k127_4040026_2	861299.J421_0065	1.079e-162	533.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_4040026_0	379066.GAU_0390	0.0	1155.0	COG0567@1|root,COG0567@2|Bacteria,1ZSVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
GDHHQS3_k127_4040026_3	861299.J421_0068	8.141e-159	514.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
GDHHQS3_k127_4040026_5	861299.J421_0069	1.119e-54	201.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS3_k127_4040026_4	861299.J421_0070	9.298e-135	435.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GDHHQS3_k127_4040026_1	861299.J421_0071	2.82e-277	868.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	2.7.13.3	ko:K03407,ko:K12257	ko02020,ko02024,ko02030,ko03060,ko03070,map02020,map02024,map02030,map03060,map03070	M00335,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	2.A.6.4	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_4084768_1	1200792.AKYF01000010_gene2718	8.018e-42	159.0	COG4538@1|root,COG4538@2|Bacteria,1V7Q1@1239|Firmicutes,4HJ77@91061|Bacilli,272NS@186822|Paenibacillaceae	91061|Bacilli	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
GDHHQS3_k127_4084768_2	1234364.AMSF01000013_gene680	2.757e-23	106.0	2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria,1SDGA@1236|Gammaproteobacteria,1X89Q@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4084768_3	304371.MCP_1150	3.773e-13	78.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
GDHHQS3_k127_4084768_0	861299.J421_1674	7.186e-97	324.0	COG1472@1|root,COG1472@2|Bacteria,1ZUGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_4125622_5	130081.XP_005707835.1	2.795e-21	100.0	COG0077@1|root,KOG2797@2759|Eukaryota	2759|Eukaryota	E	arogenate dehydratase activity	-	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51,4.2.1.91	ko:K05359,ko:K20102	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	PDT
GDHHQS3_k127_4125622_2	1379270.AUXF01000002_gene1567	1.567e-117	411.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_4125622_0	861299.J421_6016	6.043e-246	782.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4125622_1	1288494.EBAPG3_30800	1.744e-159	512.0	COG0620@1|root,COG0620@2|Bacteria,1PWDP@1224|Proteobacteria,2WBYB@28216|Betaproteobacteria,3740I@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS3_k127_4125622_3	1380394.JADL01000002_gene1704	3.538e-64	228.0	COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,2U5RW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS3_k127_4125622_4	1254432.SCE1572_11880	1.304e-53	196.0	COG0500@1|root,COG5653@1|root,COG2226@2|Bacteria,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,42VU5@68525|delta/epsilon subdivisions,2WSGU@28221|Deltaproteobacteria,2YXKC@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GDHHQS3_k127_4156983_1	1379270.AUXF01000006_gene257	2.433e-69	241.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_4156983_0	861299.J421_3265	2.341e-165	532.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_4156983_2	459349.CLOAM0342	5.505e-37	143.0	COG0041@1|root,COG0041@2|Bacteria,2NPN4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS3_k127_4156983_3	693986.MOC_5568	5.532e-30	120.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,1JU8R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_4159837_4	1379270.AUXF01000002_gene1784	4.871e-187	598.0	COG1158@1|root,COG1158@2|Bacteria,1ZTA0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
GDHHQS3_k127_4159837_8	335543.Sfum_0758	4.699e-32	145.0	COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_4159837_0	861299.J421_2339	0.0	1155.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS3_k127_4159837_3	658187.LDG_5060	1.018e-212	674.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,1JCZW@118969|Legionellales	118969|Legionellales	I	Acyl-CoA dehydrogenase, middle domain	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
GDHHQS3_k127_4159837_5	861299.J421_1663	1.398e-151	488.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GDHHQS3_k127_4159837_7	240292.Ava_3892	1.237e-40	159.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HM2J@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS3_k127_4159837_2	861299.J421_2337	4.076e-215	677.0	COG0624@1|root,COG0624@2|Bacteria,1ZT2K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_4159837_9	1246459.KB898379_gene3529	1.075e-26	113.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,4BESE@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS3_k127_4159837_1	861299.J421_2334	5.506e-259	816.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_4159837_6	379066.GAU_0440	1.252e-104	346.0	COG1960@1|root,COG1960@2|Bacteria,1ZUHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_4171734_6	861299.J421_0899	1.229e-25	112.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
GDHHQS3_k127_4171734_3	861299.J421_4501	2.327e-59	220.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4501|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4171734_4	690850.Desaf_2943	1.033e-51	188.0	COG1247@1|root,COG1247@2|Bacteria,1QU4K@1224|Proteobacteria	1224|Proteobacteria	M	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_4171734_0	1089547.KB913013_gene3982	9.422e-167	554.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,47MSB@768503|Cytophagia	976|Bacteroidetes	S	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase,SGL
GDHHQS3_k127_4171734_5	1173027.Mic7113_4526	2.825e-33	138.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria,1HBXF@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
GDHHQS3_k127_4171734_1	323848.Nmul_A1253	4.797e-161	529.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,371VR@32003|Nitrosomonadales	28216|Betaproteobacteria	P	von Willebrand factor, type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
GDHHQS3_k127_4171734_2	861299.J421_4384	5.202e-129	416.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
GDHHQS3_k127_4209990_7	861299.J421_4441	1.277e-17	84.0	COG1434@1|root,COG1434@2|Bacteria,1ZV4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS3_k127_4209990_1	378806.STAUR_1231	4.158e-194	615.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YZ0Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_4209990_3	861299.J421_4341	1.633e-103	344.0	COG2084@1|root,COG2084@2|Bacteria,1ZT54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_4209990_6	1379270.AUXF01000002_gene1484	1.087e-38	153.0	2B3Y0@1|root,31WN1@2|Bacteria,1ZUEY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4209990_5	1300345.LF41_1458	3.257e-69	250.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,Peptidase_M29
GDHHQS3_k127_4209990_4	379066.GAU_1514	1.352e-78	266.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GDHHQS3_k127_4209990_2	861299.J421_3142	3.583e-171	541.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_4209990_0	861299.J421_3143	8.954e-210	676.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS3_k127_4209990_8	379066.GAU_1518	5.109e-12	76.0	COG1196@1|root,COG1196@2|Bacteria,1ZU4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4340789_7	861299.J421_3428	2.903e-33	129.0	COG0624@1|root,COG0624@2|Bacteria,1ZSV0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_4340789_1	861299.J421_3427	4.402e-155	497.0	COG0136@1|root,COG0136@2|Bacteria,1ZTBS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Semialdehyde dehydrogenase, NAD binding domain	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_4340789_0	861299.J421_3426	4.475e-177	567.0	COG0527@1|root,COG0527@2|Bacteria,1ZSXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_4340789_5	861299.J421_3425	7.176e-69	248.0	COG0289@1|root,COG0289@2|Bacteria,1ZTHH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GDHHQS3_k127_4340789_4	861299.J421_3424	3.23e-121	395.0	COG0329@1|root,COG0329@2|Bacteria,1ZSM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS3_k127_4340789_3	861299.J421_3423	1.149e-122	400.0	COG2171@1|root,COG2171@2|Bacteria,1ZT1D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
GDHHQS3_k127_4340789_2	861299.J421_3422	3.435e-144	468.0	COG0128@1|root,COG0128@2|Bacteria	2|Bacteria	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
GDHHQS3_k127_4340789_6	861299.J421_3421	3.071e-63	226.0	COG0283@1|root,COG0283@2|Bacteria,1ZSNA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19,2.7.4.25	ko:K00800,ko:K00945	ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230	M00022,M00052	R00158,R00512,R01665,R03460	RC00002,RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
GDHHQS3_k127_4340789_8	379066.GAU_1789	4.149e-09	59.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS3_k127_440454_0	861299.J421_6223	2.667e-249	794.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_440454_2	861299.J421_1295	2.424e-55	201.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_440454_1	861299.J421_6340	1.449e-109	359.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_440454_3	861299.J421_6341	1.113e-47	173.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_440454_4	591157.SSLG_00984	4.02e-07	62.0	COG0265@1|root,COG0265@2|Bacteria,2GMIN@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	sprD	-	-	ko:K18547	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Pro_Al_protease,Trypsin
GDHHQS3_k127_440454_6	1121936.AUHI01000007_gene2482	0.0004975	47.0	2AYP4@1|root,31QTN@2|Bacteria,1V7PG@1239|Firmicutes,4HKA0@91061|Bacilli	91061|Bacilli	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,Cu_amine_oxidN1,Gmad2
GDHHQS3_k127_4427016_2	323261.Noc_1386	6.724e-23	103.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
GDHHQS3_k127_4427016_1	991.IW20_19595	5.605e-37	154.0	2BRV7@1|root,32KVE@2|Bacteria,4PD5M@976|Bacteroidetes,1INBA@117743|Flavobacteriia,2NYX2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4427016_0	224911.27355324	1.183e-77	266.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,3JTRK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS3_k127_445289_3	1210884.HG799466_gene12816	9.195e-31	132.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_445289_0	926560.KE387023_gene2723	5.98e-104	348.0	COG3437@1|root,COG3437@2|Bacteria,1WM50@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
GDHHQS3_k127_445289_1	379066.GAU_2793	1.436e-103	344.0	COG2321@1|root,COG2321@2|Bacteria,1ZSN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS3_k127_445289_4	1479239.JQMU01000001_gene1659	1.4e-26	117.0	COG5528@1|root,COG5528@2|Bacteria,1MYF3@1224|Proteobacteria,2VGW5@28211|Alphaproteobacteria,2K5ER@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GDHHQS3_k127_445289_2	234267.Acid_1844	3.201e-52	188.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4491778_0	580332.Slit_2525	3.759e-81	276.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS3_k127_4491778_1	580332.Slit_2524	2.929e-68	242.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2VRQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
GDHHQS3_k127_4491778_2	580332.Slit_2523	8.75e-28	115.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
GDHHQS3_k127_4498769_6	1379270.AUXF01000003_gene3843	1.152e-37	143.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_4498769_7	1379270.AUXF01000001_gene2516	2.189e-34	141.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
GDHHQS3_k127_4498769_2	861299.J421_3618	9.412e-77	263.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_4498769_1	861299.J421_3617	9.651e-116	376.0	COG0811@1|root,COG0811@2|Bacteria,1ZTH1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS3_k127_4498769_4	1379270.AUXF01000003_gene3846	1.904e-47	175.0	COG0848@1|root,COG0848@2|Bacteria,1ZTTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_4498769_8	279238.Saro_0014	2.748e-05	51.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS3_k127_4498769_3	861299.J421_3614	3.275e-48	183.0	2C803@1|root,33Q52@2|Bacteria,1ZTK6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4498769_0	204669.Acid345_3285	4.601e-157	510.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_4498769_5	1267535.KB906767_gene2605	1.292e-44	170.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_4500097_1	500633.CLOHIR_00192	0.0001938	48.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,25QDK@186804|Peptostreptococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
GDHHQS3_k127_4500097_0	82654.Pse7367_2104	8.666e-52	186.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_4515058_1	595537.Varpa_2261	1.709e-109	369.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,4AAJ6@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4515058_4	1297742.A176_01132	1.258e-38	147.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_4515058_5	1288494.EBAPG3_4640	8.314e-37	143.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2WA6I@28216|Betaproteobacteria,3749W@32003|Nitrosomonadales	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_4515058_3	264198.Reut_B4583	2.42e-53	194.0	COG3797@1|root,COG3797@2|Bacteria,1N1TC@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_4515058_0	296591.Bpro_1369	3.769e-189	603.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VJHX@28216|Betaproteobacteria,4ACRX@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
GDHHQS3_k127_4515058_2	1123008.KB905693_gene1405	2.842e-74	254.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia,22WIN@171551|Porphyromonadaceae	976|Bacteroidetes	G	F5 8 type C domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
GDHHQS3_k127_4516756_1	1313304.CALK_0442	1.298e-30	138.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_4516756_0	1379270.AUXF01000006_gene97	4.166e-49	196.0	2C3N7@1|root,33YDV@2|Bacteria,1ZTRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4523754_1	379066.GAU_1392	3.63e-62	215.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_4523754_0	861299.J421_3042	7.105e-320	991.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
GDHHQS3_k127_4523754_2	272560.BPSL1357	9.453e-27	113.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1K2R5@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
GDHHQS3_k127_4540591_6	580332.Slit_2572	1.279e-51	187.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4540591_2	861299.J421_4352	5.488e-119	388.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS3_k127_4540591_3	886293.Sinac_0383	9.454e-106	357.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_4540591_5	886293.Sinac_0383	1.795e-91	316.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_4540591_0	861299.J421_4355	2.149e-186	599.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4540591_4	861299.J421_4356	2.779e-93	315.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_4540591_1	861299.J421_4357	6.372e-124	408.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4540591_7	1379270.AUXF01000001_gene2650	4.827e-33	130.0	COG4591@1|root,COG4591@2|Bacteria	1379270.AUXF01000001_gene2650|-	M	lipoprotein localization to outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4542428_4	861299.J421_3569	3.15e-31	128.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_4542428_1	861299.J421_3570	8.611e-172	562.0	COG0399@1|root,COG0399@2|Bacteria,1ZT81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_4542428_0	1379270.AUXF01000003_gene3890	9.951e-180	567.0	COG0673@1|root,COG0673@2|Bacteria,1ZSQ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_4542428_3	515635.Dtur_0577	2.378e-79	272.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
GDHHQS3_k127_4542428_2	861299.J421_3571	1.251e-125	407.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS3_k127_4543713_5	869210.Marky_1927	7.469e-11	64.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS3_k127_4543713_1	861299.J421_1374	1.878e-87	302.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd2	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_4543713_2	1210884.HG799465_gene11339	8.046e-61	215.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_4543713_3	234267.Acid_3868	1.322e-57	209.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS3_k127_4543713_4	379066.GAU_1320	1.273e-30	126.0	COG4319@1|root,COG4319@2|Bacteria,1ZV6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4543713_0	1267535.KB906767_gene244	6.941e-115	376.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria,2JHMU@204432|Acidobacteriia	204432|Acidobacteriia	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GDHHQS3_k127_45473_2	1379270.AUXF01000003_gene3394	3.406e-132	429.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS3_k127_45473_4	861299.J421_6361	1.662e-24	115.0	2F5SD@1|root,33YB8@2|Bacteria,1ZUXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_45473_5	1379270.AUXF01000002_gene1199	2.028e-17	88.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_45473_1	1379698.RBG1_1C00001G1210	1.926e-133	440.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_45473_3	861299.J421_3988	3.841e-86	302.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_45473_0	1379270.AUXF01000003_gene3384	7.144e-181	576.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_45473_6	756067.MicvaDRAFT_4224	6.152e-06	59.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1H88B@1150|Oscillatoriales	1117|Cyanobacteria	M	Lipid A core - O-antigen ligase	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
GDHHQS3_k127_4555933_0	861299.J421_2945	6.304e-239	767.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS3_k127_4555933_2	861299.J421_2946	3.094e-68	250.0	COG3087@1|root,COG3087@2|Bacteria,1ZTII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GDHHQS3_k127_4555933_1	861299.J421_2947	7.037e-116	389.0	COG3087@1|root,COG3087@2|Bacteria,1ZSYS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GDHHQS3_k127_4555933_3	861299.J421_2948	5.044e-09	58.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
GDHHQS3_k127_4563590_1	1266925.JHVX01000003_gene499	1.537e-78	283.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WGWX@28216|Betaproteobacteria,37279@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
GDHHQS3_k127_4563590_2	323848.Nmul_A0637	5.098e-11	73.0	COG3103@1|root,COG3103@2|Bacteria,1NQ5X@1224|Proteobacteria,2WA5G@28216|Betaproteobacteria,372RR@32003|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM SH3, type 3	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS3_k127_4563590_0	383372.Rcas_4246	5.314e-165	529.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,376G5@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS3_k127_4568585_5	663610.JQKO01000009_gene477	2.63e-71	246.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3NAVA@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
GDHHQS3_k127_4568585_3	1266925.JHVX01000001_gene2478	7.64e-102	343.0	COG0122@1|root,COG0122@2|Bacteria,1PDQF@1224|Proteobacteria,2VH56@28216|Betaproteobacteria,373RN@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HhH-GPD superfamily base excision DNA repair protein	alkA	-	3.2.2.21	ko:K01247,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlkA_N,HhH-GPD
GDHHQS3_k127_4568585_2	1158292.JPOE01000005_gene1052	1.043e-113	374.0	COG3892@1|root,COG3892@2|Bacteria	2|Bacteria	G	5-dehydro-2-deoxygluconokinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF2090,PfkB
GDHHQS3_k127_4568585_4	861299.J421_5675	2.14e-101	335.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS3_k127_4568585_11	266117.Rxyl_2821	9.526e-26	110.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_4568585_1	266117.Rxyl_2563	9.093e-132	426.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4CRSB@84995|Rubrobacteria	84995|Rubrobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
GDHHQS3_k127_4568585_0	1382306.JNIM01000001_gene2762	1.971e-159	517.0	COG2079@1|root,COG2079@2|Bacteria,2G8X4@200795|Chloroflexi	200795|Chloroflexi	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GDHHQS3_k127_4568585_14	931277.C448_03656	5.975e-07	61.0	COG0589@1|root,arCOG02053@2157|Archaea,2XWQF@28890|Euryarchaeota,23VDK@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_4568585_7	861299.J421_5670	3.013e-51	192.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4568585_6	266117.Rxyl_2566	5.984e-63	221.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	yjbH	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_5
GDHHQS3_k127_4568585_10	1134912.AJTV01000006_gene1241	1.31e-33	133.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2UCUJ@28211|Alphaproteobacteria,36YN3@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS3_k127_4568585_8	1232410.KI421413_gene884	3.141e-46	174.0	COG3794@1|root,COG3794@2|Bacteria,1RGHH@1224|Proteobacteria	1224|Proteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
GDHHQS3_k127_4568585_9	1408224.SAMCCGM7_c6010	1.51e-40	156.0	2D7A9@1|root,32TNM@2|Bacteria,1RJFR@1224|Proteobacteria,2UAED@28211|Alphaproteobacteria,4BJAM@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4568585_13	671143.DAMO_2364	8.408e-17	89.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	prhJ	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HisKA,PAS,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_4587780_7	379066.GAU_1585	9.296e-31	123.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_4587780_8	379066.GAU_1586	1.152e-29	127.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
GDHHQS3_k127_4587780_3	861299.J421_3220	9.681e-114	378.0	COG1044@1|root,COG1044@2|Bacteria,1ZSRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS3_k127_4587780_0	861299.J421_3221	1.88e-186	590.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
GDHHQS3_k127_4587780_4	861299.J421_3222	1.197e-108	357.0	COG1043@1|root,COG1043@2|Bacteria,1ZT7T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GDHHQS3_k127_4587780_2	861299.J421_3223	1.706e-127	418.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_4587780_1	861299.J421_3224	1.018e-135	441.0	COG0763@1|root,COG0763@2|Bacteria,1ZTAD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS3_k127_4587780_5	861299.J421_3225	4.916e-59	214.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
GDHHQS3_k127_4587780_6	1379270.AUXF01000006_gene295	6.336e-50	186.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
GDHHQS3_k127_4593954_7	936455.KI421499_gene2064	3.672e-36	146.0	COG0438@1|root,COG0438@2|Bacteria,1R5CX@1224|Proteobacteria,2U4XZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4593954_3	107635.AZUO01000001_gene2086	1.499e-95	322.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2U57D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	transport, permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GDHHQS3_k127_4593954_2	1123242.JH636435_gene2139	8.537e-110	368.0	COG1134@1|root,COG1134@2|Bacteria,2IX6N@203682|Planctomycetes	203682|Planctomycetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GDHHQS3_k127_4593954_5	243231.GSU2248	4.066e-70	248.0	COG1215@1|root,COG1215@2|Bacteria,1QXP2@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4593954_4	1121403.AUCV01000031_gene2829	1.81e-78	273.0	COG1091@1|root,COG1091@2|Bacteria,1Q48H@1224|Proteobacteria,42YKE@68525|delta/epsilon subdivisions,2WTPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS3_k127_4593954_1	314278.NB231_16878	1.005e-128	421.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WXX0@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
GDHHQS3_k127_4593954_0	1122947.FR7_2451	3.388e-132	432.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H3QB@909932|Negativicutes	909932|Negativicutes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS3_k127_4593954_6	315456.RF_0543	7.17e-51	192.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2UBCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_4603646_11	1210884.HG799465_gene11637	4.944e-38	149.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
GDHHQS3_k127_4603646_19	330214.NIDE1139	2.404e-21	98.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,DUF3565
GDHHQS3_k127_4603646_25	379066.GAU_2766	7.494e-05	46.0	COG2132@1|root,COG2132@2|Bacteria,1ZUZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
GDHHQS3_k127_4603646_8	357808.RoseRS_0914	6.368e-42	168.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_4603646_5	1117943.SFHH103_02774	8.053e-62	230.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_4603646_23	1210908.HSB1_47760	4.458e-09	61.0	COG0701@1|root,arCOG02712@2157|Archaea,2XU5I@28890|Euryarchaeota,23T00@183963|Halobacteria	183963|Halobacteria	S	metal ion permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,YHS
GDHHQS3_k127_4603646_6	861299.J421_5747	2.139e-60	218.0	2AEQK@1|root,314M5@2|Bacteria,1ZTRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
GDHHQS3_k127_4603646_26	477974.Daud_1641	0.0002106	53.0	COG0589@1|root,COG0589@2|Bacteria,1VF2J@1239|Firmicutes,24SWJ@186801|Clostridia	186801|Clostridia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_4603646_14	78245.Xaut_1403	4.291e-34	138.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2U9JR@28211|Alphaproteobacteria,3EZV0@335928|Xanthobacteraceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4603646_10	525904.Tter_2724	3.511e-38	147.0	COG3439@1|root,COG3439@2|Bacteria,2NPV1@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GDHHQS3_k127_4603646_22	749222.Nitsa_1475	6.743e-15	80.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS3_k127_4603646_1	1392490.JHZX01000001_gene2235	1.106e-104	346.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_4603646_18	1094980.Mpsy_1166	1.089e-21	101.0	COG0517@1|root,arCOG00606@2157|Archaea,2XZ85@28890|Euryarchaeota,2N9UA@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_4603646_2	693986.MOC_4620	3.221e-75	259.0	COG0412@1|root,COG0412@2|Bacteria,1R6AF@1224|Proteobacteria,2U0YG@28211|Alphaproteobacteria,1JUW3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_4603646_0	1173024.KI912151_gene2146	1.349e-187	595.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
GDHHQS3_k127_4603646_3	483219.LILAB_29390	6.841e-67	236.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2X0CC@28221|Deltaproteobacteria,2Z0IE@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS3_k127_4603646_4	639030.JHVA01000001_gene3713	2.345e-62	223.0	COG2823@1|root,COG2823@2|Bacteria,3Y7T6@57723|Acidobacteria,2JN0K@204432|Acidobacteriia	204432|Acidobacteriia	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS3_k127_4603646_7	251229.Chro_3389	2.505e-53	198.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_4603646_9	383372.Rcas_3776	5.773e-41	164.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_4603646_21	1192034.CAP_0163	6.918e-19	101.0	COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,2YUR5@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS3_k127_4603646_27	391625.PPSIR1_11070	0.0003183	53.0	2AIWV@1|root,319EH@2|Bacteria,1Q2HT@1224|Proteobacteria,433TN@68525|delta/epsilon subdivisions,2X3EP@28221|Deltaproteobacteria,2YVQT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4603646_13	589924.Ferp_2107	1.716e-36	158.0	arCOG06549@1|root,arCOG06549@2157|Archaea,2Y31C@28890|Euryarchaeota,246R3@183980|Archaeoglobi	183980|Archaeoglobi	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
GDHHQS3_k127_4603646_20	1191523.MROS_2048	5.488e-19	101.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
GDHHQS3_k127_4603646_12	861299.J421_0446	5.102e-37	149.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4603646_17	671143.DAMO_1586	9.013e-24	108.0	COG3088@1|root,COG3088@2|Bacteria,2NRBD@2323|unclassified Bacteria	2|Bacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH
GDHHQS3_k127_4603646_15	40571.JOEA01000041_gene4666	5.509e-32	135.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4E3DR@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
GDHHQS3_k127_4603646_16	671143.DAMO_1588	1.179e-31	130.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198,ko:K04016	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS3_k127_4626491_6	443906.CMM_0825	7.998e-12	78.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
GDHHQS3_k127_4626491_8	517722.AEUE01000007_gene331	3.698e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,1NVNI@1224|Proteobacteria,2V5R9@28211|Alphaproteobacteria,2K5BM@204457|Sphingomonadales	204457|Sphingomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_4626491_0	1167006.UWK_02693	3.998e-135	445.0	COG0741@1|root,COG1716@1|root,COG0741@2|Bacteria,COG1716@2|Bacteria,1NQQQ@1224|Proteobacteria	1224|Proteobacteria	MT	PFAM Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,SLT
GDHHQS3_k127_4626491_2	1267533.KB906738_gene2351	1.265e-56	208.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
GDHHQS3_k127_4626491_1	404589.Anae109_3359	3.846e-85	294.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
GDHHQS3_k127_4626491_4	1283300.ATXB01000001_gene437	2.176e-18	95.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,UnbV_ASPIC,VCBS
GDHHQS3_k127_4626491_3	572544.Ilyop_0968	2.99e-19	95.0	COG1622@1|root,COG1622@2|Bacteria,37CJY@32066|Fusobacteria	2|Bacteria	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
GDHHQS3_k127_4626491_5	1356852.N008_12080	2.242e-16	89.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4629107_8	861299.J421_3825	2.338e-05	53.0	COG0806@1|root,COG0806@2|Bacteria,1ZU43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_4629107_7	1379270.AUXF01000003_gene3591	5.827e-35	136.0	COG0228@1|root,COG0228@2|Bacteria,1ZTWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S16	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS3_k127_4629107_1	861299.J421_3827	6.758e-221	691.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS3_k127_4629107_0	861299.J421_3828	0.0	1250.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_4629107_2	379066.GAU_2350	2.655e-103	363.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4629107_4	1379270.AUXF01000003_gene3576	1.003e-87	300.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS3_k127_4629107_5	861299.J421_3833	1.051e-67	239.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS3_k127_4629107_3	861299.J421_3834	9.595e-92	310.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS3_k127_4629107_6	926561.KB900617_gene1403	8.189e-56	202.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3WB2U@53433|Halanaerobiales	186801|Clostridia	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
GDHHQS3_k127_463283_13	861299.J421_2063	1.314e-28	116.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS3_k127_463283_12	1247726.MIM_c09640	7.004e-30	124.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,3T4K8@506|Alcaligenaceae	28216|Betaproteobacteria	B	SWIB/MDM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
GDHHQS3_k127_463283_3	861299.J421_2065	9.823e-116	379.0	COG0681@1|root,COG0681@2|Bacteria,1ZTFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS3_k127_463283_14	861299.J421_2067	8.609e-28	121.0	2BYRT@1|root,345RZ@2|Bacteria,1ZU2R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_463283_7	861299.J421_2070	5.85e-58	204.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
GDHHQS3_k127_463283_4	379066.GAU_3054	3.846e-112	376.0	COG1668@1|root,COG1668@2|Bacteria,1ZTID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_463283_2	861299.J421_2075	1.318e-154	494.0	COG4152@1|root,COG4152@2|Bacteria,1ZSSG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_463283_6	670292.JH26_03880	3.58e-70	246.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_463283_10	755732.Fluta_0862	1.54e-37	145.0	2C4H4@1|root,32CX0@2|Bacteria,4NX86@976|Bacteroidetes,1I5D2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_463283_9	379066.GAU_0945	4.261e-55	206.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS3_k127_463283_8	861299.J421_5956	1.033e-55	201.0	2CDAN@1|root,3134Z@2|Bacteria,1ZU58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS3_k127_463283_0	861299.J421_5957	3.578e-309	955.0	COG2303@1|root,COG2303@2|Bacteria,1ZSZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_463283_1	395495.Lcho_1954	6.398e-229	719.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KJ6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
GDHHQS3_k127_463283_5	1379270.AUXF01000001_gene2755	3.128e-71	263.0	2EZKR@1|root,33SRW@2|Bacteria,1ZSQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_463283_16	1078020.KEK_04452	1.055e-14	76.0	29RUC@1|root,30CY9@2|Bacteria,2GW9D@201174|Actinobacteria,23C68@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
GDHHQS3_k127_463283_11	861299.J421_0746	1.782e-35	141.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_4640098_1	518766.Rmar_1309	5.457e-216	698.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1FIVX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GDHHQS3_k127_4640098_16	1379270.AUXF01000005_gene823	1.572e-36	141.0	COG0858@1|root,COG0858@2|Bacteria,1ZTWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS3_k127_4640098_9	861299.J421_3190	6.225e-66	235.0	COG0130@1|root,COG0130@2|Bacteria,1ZTJM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
GDHHQS3_k127_4640098_2	861299.J421_3191	5.446e-119	390.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS3_k127_4640098_0	1379270.AUXF01000005_gene826	1.699e-218	691.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_4640098_3	861299.J421_3193	5.107e-115	379.0	COG0341@1|root,COG0341@2|Bacteria,1ZSSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_4640098_12	1122147.AUEH01000024_gene1834	1.777e-45	174.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae	91061|Bacilli	L	hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS3_k127_4640098_14	861299.J421_3195	1.149e-40	156.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_4640098_6	644282.Deba_3173	2.096e-90	307.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_4640098_17	1379270.AUXF01000005_gene830	9.613e-26	116.0	2FIMZ@1|root,34ADU@2|Bacteria,1ZTYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4640098_7	443144.GM21_0260	4.398e-86	294.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
GDHHQS3_k127_4640098_5	861299.J421_3198	4.822e-107	351.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
GDHHQS3_k127_4640098_13	861299.J421_3199	1.64e-44	167.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
GDHHQS3_k127_4640098_8	1379270.AUXF01000005_gene834	2.949e-85	308.0	COG0652@1|root,COG0652@2|Bacteria,1ZUUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS3_k127_4640098_11	861299.J421_3201	4.987e-58	207.0	2EPTK@1|root,33HE4@2|Bacteria,1ZTUK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
GDHHQS3_k127_4640098_10	861299.J421_3202	3.722e-60	213.0	COG0615@1|root,COG0615@2|Bacteria,1ZTPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GDHHQS3_k127_4640098_4	1379270.AUXF01000005_gene838	2.208e-111	364.0	COG0689@1|root,COG0689@2|Bacteria,1ZSYT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GDHHQS3_k127_4640098_15	379066.GAU_1572	3.127e-40	162.0	COG0127@1|root,COG0127@2|Bacteria,1ZTSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS3_k127_4640098_18	379066.GAU_2523	3.167e-18	90.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_4655279_16	1123261.AXDW01000007_gene2279	2.45e-19	91.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4655279_1	929556.Solca_3465	3.325e-265	827.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_4655279_2	861299.J421_1944	6.877e-221	699.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
GDHHQS3_k127_4655279_12	1268072.PSAB_16215	1.664e-33	134.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_4655279_7	756067.MicvaDRAFT_2416	1.188e-67	237.0	COG0546@1|root,COG0546@2|Bacteria,1G1NK@1117|Cyanobacteria,1H8PP@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_4655279_17	1266925.JHVX01000002_gene754	3.341e-16	87.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,373S6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
GDHHQS3_k127_4655279_6	756067.MicvaDRAFT_0903	1.087e-71	250.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE2,HAMP,PAS,PAS_9,SpoIIE,dCache_1
GDHHQS3_k127_4655279_5	861299.J421_4220	9.041e-110	365.0	COG2367@1|root,COG2367@2|Bacteria,1ZT83@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS3_k127_4655279_15	1197906.CAJQ02000047_gene4077	3.997e-23	103.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4655279_10	861299.J421_4072	1.328e-47	177.0	COG2010@1|root,COG2010@2|Bacteria,1ZU6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
GDHHQS3_k127_4655279_0	861299.J421_4070	6.709e-314	970.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
GDHHQS3_k127_4655279_13	1230457.C476_04023	1.973e-32	134.0	COG2020@1|root,arCOG03580@2157|Archaea,2XXQD@28890|Euryarchaeota,23W11@183963|Halobacteria	183963|Halobacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_4655279_4	240015.ACP_2729	2.372e-117	385.0	COG0031@1|root,COG0031@2|Bacteria,3Y45Z@57723|Acidobacteria,2JHUN@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_4655279_9	221288.JH992901_gene2489	1.891e-53	196.0	COG1670@1|root,COG1670@2|Bacteria,1G621@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_4655279_11	861299.J421_0718	8.106e-41	159.0	2F4AY@1|root,33X1J@2|Bacteria,1ZTWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4655279_3	713586.KB900536_gene2395	1.178e-137	445.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
GDHHQS3_k127_4655279_8	379066.GAU_2027	1.117e-62	224.0	COG1802@1|root,COG1802@2|Bacteria,1ZUBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS3_k127_4724468_2	1379270.AUXF01000003_gene3510	4.89e-48	181.0	2F4EZ@1|root,33X55@2|Bacteria,1ZTSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4724468_1	379066.GAU_2413	6.161e-76	259.0	COG0218@1|root,COG0218@2|Bacteria,1ZTHF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
GDHHQS3_k127_4724468_0	1379270.AUXF01000003_gene3512	9.978e-254	794.0	COG0466@1|root,COG0466@2|Bacteria,1ZT5P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_4741723_1	402626.Rpic_4115	4.022e-59	213.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,1K5JG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GDHHQS3_k127_4741723_2	1279009.ADICEAN_03673	6.938e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,4P4RR@976|Bacteroidetes	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_4741723_0	661367.LLO_0670	1.397e-111	387.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1JC52@118969|Legionellales	118969|Legionellales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS3_k127_4741723_3	1379270.AUXF01000001_gene2417	2.782e-39	152.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_4768966_10	1379270.AUXF01000005_gene488	2.579e-12	67.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_4768966_2	861299.J421_2931	4.201e-116	388.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
GDHHQS3_k127_4768966_9	1469245.JFBG01000083_gene257	4.451e-27	119.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GDHHQS3_k127_4768966_4	56110.Oscil6304_0189	5.524e-73	266.0	COG0642@1|root,COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,1G3F2@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,Response_reg
GDHHQS3_k127_4768966_8	269799.Gmet_0377	4.223e-27	112.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS3_k127_4768966_1	379066.GAU_1184	4.216e-145	467.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_4768966_3	861299.J421_2937	1.734e-82	284.0	COG2890@1|root,COG2890@2|Bacteria,1ZTQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
GDHHQS3_k127_4768966_6	861299.J421_2938	1.38e-42	158.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
GDHHQS3_k127_4768966_5	861299.J421_2939	1.247e-57	211.0	COG0125@1|root,COG0125@2|Bacteria,1ZTPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS3_k127_4768966_0	861299.J421_2940	6.113e-175	565.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
GDHHQS3_k127_4768966_7	243365.CV_3423	2.793e-27	124.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,2VS2J@28216|Betaproteobacteria,2KR6Q@206351|Neisseriales	206351|Neisseriales	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GDHHQS3_k127_4807586_2	1379270.AUXF01000006_gene255	4.874e-132	426.0	COG0304@1|root,COG0304@2|Bacteria,1ZSPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_4807586_0	1379270.AUXF01000006_gene256	1.315e-181	576.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_4807586_3	861299.J421_3266	1.304e-119	389.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_4807586_1	861299.J421_3265	2.654e-174	550.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_4810188_4	861299.J421_2916	1.435e-19	93.0	28R18@1|root,2ZDFV@2|Bacteria,1ZU2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4810188_1	234267.Acid_5756	2.086e-60	223.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_4810188_2	1254432.SCE1572_21210	9.803e-49	185.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4810188_5	1379698.RBG1_1C00001G0272	2.757e-16	87.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF2505
GDHHQS3_k127_4810188_0	379066.GAU_1164	3.155e-168	543.0	COG0606@1|root,COG0606@2|Bacteria,1ZSXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4810188_6	290397.Adeh_3337	0.0002543	44.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS3_k127_4826362_1	379066.GAU_2162	2.115e-27	112.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_4826362_0	1101192.KB910516_gene93	1.896e-162	523.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,1JT2Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Acts as a magnesium transporter	mgtE	GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_4834530_2	583355.Caka_1913	3.071e-38	151.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_4834530_0	1121918.ARWE01000001_gene245	1.231e-147	504.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,43TYD@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
GDHHQS3_k127_4834530_1	583355.Caka_1913	6.559e-55	198.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_484821_7	861299.J421_3400	5.997e-68	237.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_484821_2	861299.J421_3399	4.316e-192	604.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS3_k127_484821_1	861299.J421_3398	8.695e-202	631.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_484821_6	379066.GAU_1760	1.912e-73	261.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS3_k127_484821_8	861299.J421_3396	1.415e-54	199.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
GDHHQS3_k127_484821_0	861299.J421_3395	5.31e-220	702.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_484821_3	379066.GAU_1757	3.411e-168	541.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_484821_4	379066.GAU_1756	4.916e-145	463.0	COG0777@1|root,COG0777@2|Bacteria,1ZSSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_484821_5	861299.J421_3392	2.137e-115	392.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
GDHHQS3_k127_4859390_1	887062.HGR_08199	2.87e-11	70.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AAJP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS3_k127_4859390_2	450851.PHZ_c2439	1.158e-06	59.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2TQQI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4859390_0	243231.GSU2476	3.151e-134	449.0	COG0457@1|root,COG4076@1|root,COG0457@2|Bacteria,COG4076@2|Bacteria,1MUZK@1224|Proteobacteria,42WF6@68525|delta/epsilon subdivisions,2WS8U@28221|Deltaproteobacteria,43U1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_4861802_3	861299.J421_2624	4.325e-156	497.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_4861802_17	1121287.AUMU01000010_gene1805	1.336e-05	48.0	29EH7@1|root,301F5@2|Bacteria,4PGMM@976|Bacteroidetes,1IHES@117743|Flavobacteriia,3ZU3J@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4861802_15	1238182.C882_3875	9.01e-08	63.0	2EJPN@1|root,33DEG@2|Bacteria,1NJ0G@1224|Proteobacteria,2UKKF@28211|Alphaproteobacteria,2JUH8@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4861802_0	861299.J421_4050	0.0	1142.0	COG5549@1|root,COG5549@2|Bacteria,1ZTC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
GDHHQS3_k127_4861802_14	379066.GAU_0011	1.968e-17	91.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_4861802_18	1415778.JQMM01000001_gene2084	0.0007807	45.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4861802_8	861299.J421_1786	3.132e-59	217.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS3_k127_4861802_11	861299.J421_3138	4.874e-34	139.0	2F4AY@1|root,33YV0@2|Bacteria,1ZU13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4861802_10	861299.J421_2331	8.773e-35	147.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667,HlyD_3
GDHHQS3_k127_4861802_1	204669.Acid345_1748	8.434e-203	646.0	COG0492@1|root,COG0492@2|Bacteria,3Y3SH@57723|Acidobacteria,2JI51@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_4861802_7	479434.Sthe_0341	2.061e-96	318.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS3_k127_4861802_6	479434.Sthe_0342	4.782e-102	338.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS3_k127_4861802_12	1386089.N865_20590	2.699e-21	100.0	2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4FHK1@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4861802_9	1123393.KB891316_gene2013	4.884e-36	143.0	COG0025@1|root,COG0025@2|Bacteria,1QTZ5@1224|Proteobacteria,2WGIC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
GDHHQS3_k127_4861802_5	1267535.KB906767_gene2627	1.435e-108	368.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_4861802_2	596151.DesfrDRAFT_3682	1.068e-156	514.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria,2MARP@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
GDHHQS3_k127_4861802_4	861299.J421_1003	1.371e-116	394.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS3_k127_4861802_13	1379270.AUXF01000003_gene3388	7.099e-20	94.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_4881932_3	379066.GAU_1544	2.088e-114	378.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS3_k127_4881932_0	861299.J421_3175	1.823e-179	570.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS3_k127_4881932_9	861299.J421_3174	4.689e-21	100.0	2FES0@1|root,346R1@2|Bacteria,1ZU3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4881932_8	861299.J421_3172	3.96e-51	186.0	COG0745@1|root,COG0745@2|Bacteria,1ZU0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_4881932_1	861299.J421_3171	1.141e-136	443.0	COG0836@1|root,COG0836@2|Bacteria,1ZT5Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_4881932_2	861299.J421_3170	1.567e-133	438.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
GDHHQS3_k127_4881932_6	861299.J421_3169	6.041e-66	234.0	COG1235@1|root,COG1235@2|Bacteria,1ZTN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS3_k127_4881932_7	861299.J421_2234	2.73e-58	208.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
GDHHQS3_k127_4881932_5	861299.J421_1517	9.091e-68	246.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4881932_4	935567.JAES01000005_gene473	8.566e-78	264.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X4AH@135614|Xanthomonadales	135614|Xanthomonadales	E	cystathionine	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_4885606_0	861299.J421_2368	6.195e-86	293.0	2EXE5@1|root,33QQP@2|Bacteria,1ZTI3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4885606_1	861299.J421_2367	9.622e-48	182.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_48882_1	991.IW20_16285	3.3e-05	57.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4898202_0	861299.J421_0783	1.463e-131	429.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS3_k127_4898202_1	420324.KI911999_gene8065	1.736e-99	335.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,1JQQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Glucose Sorbosone dehydrogenase	yliI	-	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
GDHHQS3_k127_4911672_0	1123277.KB893174_gene5952	2.172e-117	384.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
GDHHQS3_k127_4911672_2	426117.M446_0919	8.787e-06	58.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TRSN@28211|Alphaproteobacteria,1JWZ4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
GDHHQS3_k127_4911672_1	247633.GP2143_17796	1.433e-60	221.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4937159_11	608506.COB47_1676	0.0002263	45.0	2AE8G@1|root,3142G@2|Bacteria,1V7YJ@1239|Firmicutes,24JA4@186801|Clostridia,42IC5@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS3_k127_4937159_1	1142394.PSMK_27530	2.452e-138	448.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS3_k127_4937159_0	266117.Rxyl_1977	1.493e-141	471.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS3_k127_4937159_4	379066.GAU_2594	1.318e-99	334.0	COG0181@1|root,COG0181@2|Bacteria,1ZTQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS3_k127_4937159_2	234267.Acid_2458	5.567e-124	406.0	COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria	57723|Acidobacteria	H	PFAM delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
GDHHQS3_k127_4937159_10	1385510.N781_00780	3.415e-23	101.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,4HKWM@91061|Bacilli	91061|Bacilli	K	Transcriptional	sdpR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS3_k127_4937159_7	632245.CLP_0353	2.624e-47	179.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,36IUU@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
GDHHQS3_k127_4937159_3	42256.RradSPS_2139	1.69e-115	381.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_4937159_5	861299.J421_4188	6.847e-96	316.0	COG0221@1|root,COG0221@2|Bacteria,1ZTH9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
GDHHQS3_k127_4937159_9	56107.Cylst_2200	3.573e-28	121.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HNP9@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GDHHQS3_k127_4937159_6	1278073.MYSTI_03014	5.264e-67	235.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
GDHHQS3_k127_4937159_8	649747.HMPREF0083_05364	8.081e-44	163.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,26XPE@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the metal hydrolase YfiT family	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4981255_2	861299.J421_4191	6.396e-57	203.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS3_k127_4981255_1	1379270.AUXF01000001_gene2793	1.038e-70	249.0	COG1131@1|root,COG1131@2|Bacteria,1ZTRV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS3_k127_4981255_0	861299.J421_4196	0.0	1111.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_5019051_0	1089550.ATTH01000001_gene1363	1.36e-191	612.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJZQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS3_k127_5019051_2	861299.J421_5670	7.645e-54	207.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5019051_1	580332.Slit_2525	7.453e-151	482.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS3_k127_5053384_2	269799.Gmet_0920	1.532e-21	98.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,43ADJ@68525|delta/epsilon subdivisions,2WMPS@28221|Deltaproteobacteria,43TG6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0920	SIS_2
GDHHQS3_k127_5053384_0	861299.J421_4433	0.0	1256.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5053384_3	379066.GAU_2767	3.025e-20	96.0	2DWK2@1|root,340S5@2|Bacteria,1ZTSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5053384_1	251221.35210834	4.745e-146	466.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_512732_5	935567.JAES01000016_gene1534	3.681e-25	109.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1X3M9@135614|Xanthomonadales	135614|Xanthomonadales	P	Transporter	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
GDHHQS3_k127_512732_3	861299.J421_3744	5.919e-121	395.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GDHHQS3_k127_512732_2	861299.J421_3745	9.943e-122	411.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
GDHHQS3_k127_512732_1	861299.J421_3746	1.916e-128	426.0	COG0760@1|root,COG0760@2|Bacteria,1ZT5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
GDHHQS3_k127_512732_0	1121468.AUBR01000069_gene1116	2.91e-219	719.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS3_k127_512732_6	1123508.JH636441_gene3757	2.438e-14	74.0	COG4877@1|root,COG4877@2|Bacteria,2J4M8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_512732_4	379066.GAU_3596	2.02e-101	338.0	COG0330@1|root,COG0330@2|Bacteria,1ZUIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_5138510_0	379066.GAU_2777	4.893e-292	906.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_5138510_2	861299.J421_4452	1.499e-256	814.0	COG0744@1|root,COG0744@2|Bacteria,1ZSRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_5138510_1	861299.J421_4453	9.041e-260	816.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1ZTC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS3_k127_5138510_3	1379270.AUXF01000001_gene2535	3.246e-200	630.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_5184035_5	861299.J421_1256	5.013e-80	273.0	COG2215@1|root,COG2215@2|Bacteria,1ZV92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5184035_3	379066.GAU_1869	1.094e-122	406.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS3_k127_5184035_4	1379270.AUXF01000006_gene90	6.282e-107	354.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS3_k127_5184035_0	1379270.AUXF01000006_gene89	2.023e-244	764.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS3_k127_5184035_8	861299.J421_3442	8.548e-24	107.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GDHHQS3_k127_5184035_1	1379270.AUXF01000006_gene86	5.024e-232	743.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS3_k127_5184035_2	861299.J421_3445	9.395e-134	434.0	COG0016@1|root,COG0016@2|Bacteria,1ZSQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS3_k127_5184035_7	861299.J421_3446	1.156e-51	184.0	COG0292@1|root,COG0292@2|Bacteria,1ZTUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS3_k127_5184035_9	1379270.AUXF01000006_gene83	1.457e-19	90.0	COG0291@1|root,COG0291@2|Bacteria,1ZU3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS3_k127_5184035_6	379066.GAU_1878	2.332e-79	268.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS3_k127_5184035_10	714943.Mucpa_4790	0.0006148	46.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1IT31@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_5211466_6	861299.J421_4532	8.748e-30	121.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5211466_2	379066.GAU_2851	2.456e-111	368.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
GDHHQS3_k127_5211466_5	861299.J421_4485	4.896e-32	140.0	COG1765@1|root,COG1765@2|Bacteria,1ZTV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_5211466_1	861299.J421_4484	3.311e-146	469.0	COG2897@1|root,COG2897@2|Bacteria,1ZTF6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_5211466_4	861299.J421_4482	4.637e-48	174.0	COG3411@1|root,COG3411@2|Bacteria,1ZU0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5211466_8	861299.J421_1124	3.386e-17	84.0	2EPV2@1|root,33HFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5211466_7	861299.J421_4479	2.593e-28	117.0	2FCBU@1|root,344FF@2|Bacteria,1ZU39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5211466_3	1128421.JAGA01000004_gene2517	5.509e-107	355.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS3_k127_5211466_9	861299.J421_4473	2.932e-07	63.0	2F33T@1|root,33VYR@2|Bacteria,1ZTS4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
GDHHQS3_k127_5211466_0	861299.J421_4471	4.407e-191	599.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_530151_4	861299.J421_3470	5.574e-09	58.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_530151_1	1379270.AUXF01000006_gene61	1.148e-138	449.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GDHHQS3_k127_530151_0	1379270.AUXF01000006_gene62	1.398e-167	533.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_530151_2	1379270.AUXF01000006_gene63	2.816e-82	286.0	COG2264@1|root,COG2264@2|Bacteria,1ZST2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS3_k127_530151_3	861299.J421_3466	8.781e-76	262.0	COG1385@1|root,COG1385@2|Bacteria,1ZTJ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GDHHQS3_k127_530151_5	887929.HMP0721_0671	0.0003852	45.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,25WUY@186806|Eubacteriaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS3_k127_5349916_3	861299.J421_3919	2.9e-34	138.0	COG3339@1|root,COG3339@2|Bacteria,1ZTZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS3_k127_5349916_4	861299.J421_3920	3.145e-27	117.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5349916_1	861299.J421_3921	2.039e-87	301.0	COG3108@1|root,COG3108@2|Bacteria,1ZT3M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS3_k127_5349916_2	379066.GAU_2456	3.879e-85	290.0	COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_5349916_5	379066.GAU_2457	1.4e-25	115.0	2A37A@1|root,30RNW@2|Bacteria,1ZUP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5349916_0	861299.J421_3922	2.423e-164	524.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GDHHQS3_k127_535964_3	861299.J421_2827	4.738e-24	108.0	2FCS2@1|root,344V7@2|Bacteria,1ZU5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_535964_1	1232410.KI421421_gene3566	1.305e-101	356.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_535964_5	375451.RD1_3462	3.203e-13	74.0	COG0745@1|root,COG0745@2|Bacteria,1NCKY@1224|Proteobacteria,2TRPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_535964_2	861299.J421_2833	3.5e-98	331.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_2833|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_535964_0	861299.J421_2834	3.647e-234	738.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_535964_4	861299.J421_2835	1.536e-13	76.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5392838_0	861299.J421_2986	2.514e-218	688.0	COG0008@1|root,COG0008@2|Bacteria,1ZSSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS3_k127_5392838_1	861299.J421_2985	3.626e-66	232.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_5392838_4	502025.Hoch_4319	1.185e-21	100.0	COG0346@1|root,COG0346@2|Bacteria,1NB98@1224|Proteobacteria	1224|Proteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_5392838_2	861299.J421_2984	7.707e-37	150.0	2FFNT@1|root,347K5@2|Bacteria,1ZTY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5392838_3	379066.GAU_2121	2.585e-24	104.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_5424311_5	398767.Glov_0658	5.121e-06	49.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria,43UMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
GDHHQS3_k127_5424311_3	483219.LILAB_09685	4.823e-66	230.0	COG3631@1|root,COG3631@2|Bacteria,1RDED@1224|Proteobacteria,43810@68525|delta/epsilon subdivisions,2X3B2@28221|Deltaproteobacteria,2YV6Y@29|Myxococcales	28221|Deltaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS3_k127_5424311_0	861299.J421_1737	2.529e-180	572.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
GDHHQS3_k127_5424311_2	663610.JQKO01000012_gene3076	3.081e-75	276.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_5424311_4	1278073.MYSTI_02425	6.468e-33	147.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS3_k127_5424311_1	861299.J421_0392	2.102e-93	321.0	COG1301@1|root,COG1301@2|Bacteria,1ZTDM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
GDHHQS3_k127_5480658_4	379066.GAU_1995	6.864e-08	53.0	2FD8C@1|root,345AC@2|Bacteria,1ZTXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5480658_1	861299.J421_3598	1.448e-173	552.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_5480658_0	861299.J421_3597	3.189e-178	564.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_5480658_3	379066.GAU_1994	2.457e-19	97.0	293YK@1|root,2ZRDM@2|Bacteria,1ZU6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5480658_2	204669.Acid345_4350	1.723e-124	415.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_5489859_0	861299.J421_2444	9.48e-197	626.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1ZTG4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5
GDHHQS3_k127_5489859_1	379066.GAU_0535	5.92e-77	285.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GDHHQS3_k127_5489859_3	1379270.AUXF01000002_gene1856	8.706e-66	227.0	COG0652@1|root,COG0652@2|Bacteria,1ZTQ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS3_k127_5489859_4	861299.J421_2438	3.148e-53	196.0	COG1309@1|root,COG1309@2|Bacteria,1ZTT6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GDHHQS3_k127_5489859_2	861299.J421_2432	7.532e-71	243.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5489859_7	861299.J421_2430	3.199e-08	62.0	298DU@1|root,2ZVJ1@2|Bacteria,1ZU76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5489859_8	1112217.PPL19_15474	1.225e-05	51.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS3_k127_5489859_5	379066.GAU_0523	3.261e-16	79.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GDHHQS3_k127_5539118_0	986075.CathTA2_2389	1.718e-58	215.0	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,4HC07@91061|Bacilli	91061|Bacilli	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
GDHHQS3_k127_5539118_1	1184609.KILIM_099_00140	4.202e-55	212.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,4F7CK@85018|Dermatophilaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
GDHHQS3_k127_5539118_2	557598.LHK_02076	8.715e-08	63.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,2KQ15@206351|Neisseriales	206351|Neisseriales	K	Response regulator receiver domain protein	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_555881_7	153948.NAL212_2209	6.623e-33	137.0	COG3211@1|root,COG3211@2|Bacteria,1NSHF@1224|Proteobacteria,2WGDG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
GDHHQS3_k127_555881_4	861299.J421_0860	3.024e-63	222.0	COG2353@1|root,COG2353@2|Bacteria,1ZV1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_555881_8	469371.Tbis_2088	2.858e-32	131.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4E5MM@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GDHHQS3_k127_555881_5	861299.J421_0893	1.814e-60	211.0	COG0780@1|root,COG0780@2|Bacteria,1ZTKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GDHHQS3_k127_555881_3	379066.GAU_3894	8.135e-72	252.0	COG0705@1|root,COG0705@2|Bacteria,1ZSWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_555881_2	861299.J421_0896	6.071e-126	411.0	COG1181@1|root,COG1181@2|Bacteria,1ZTFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS3_k127_555881_1	861299.J421_0897	1.224e-223	702.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS3_k127_555881_9	1379270.AUXF01000002_gene1159	6.758e-28	122.0	COG0810@1|root,COG0810@2|Bacteria,1ZV4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_555881_0	861299.J421_0903	0.0	1112.0	COG0249@1|root,COG0249@2|Bacteria,1ZST5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS3_k127_555881_6	1379270.AUXF01000002_gene1165	3.964e-39	160.0	COG1729@1|root,COG3087@1|root,COG1729@2|Bacteria,COG3087@2|Bacteria,1ZTSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_6
GDHHQS3_k127_5615476_0	861299.J421_0823	3.144e-105	350.0	COG2514@1|root,COG2514@2|Bacteria,1ZTDT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_5615476_1	1131269.AQVV01000002_gene1254	3.724e-89	316.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
GDHHQS3_k127_5615476_4	861299.J421_2553	2.664e-50	187.0	COG1437@1|root,COG1437@2|Bacteria	2|Bacteria	F	CYTH domain	mtaD	-	4.6.1.1	ko:K01768,ko:K05873	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
GDHHQS3_k127_5615476_2	861299.J421_2552	7.043e-82	292.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GDHHQS3_k127_5615476_3	1379270.AUXF01000004_gene3271	1.43e-69	246.0	COG0697@1|root,COG0697@2|Bacteria,1ZTNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_5615476_5	1379270.AUXF01000004_gene3272	7.489e-42	158.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5618485_3	861299.J421_4210	5.624e-52	200.0	COG0457@1|root,COG0457@2|Bacteria,1ZTZG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5618485_2	861299.J421_4209	1.166e-98	331.0	COG1131@1|root,COG1131@2|Bacteria,1ZV6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
GDHHQS3_k127_5618485_0	861299.J421_4207	5.989e-320	1000.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_5618485_1	861299.J421_4205	2.521e-125	418.0	2EY14@1|root,33RA2@2|Bacteria,1ZSR5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5618485_4	861299.J421_4203	2.921e-37	157.0	COG0558@1|root,COG0558@2|Bacteria,1ZTUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_5624679_5	861299.J421_3081	4.509e-58	205.0	COG0739@1|root,COG0739@2|Bacteria,1ZSUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_5624679_3	861299.J421_3083	3.93e-122	399.0	COG0552@1|root,COG0552@2|Bacteria,1ZTBT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS3_k127_5624679_0	861299.J421_3084	0.0	1024.0	COG1200@1|root,COG1200@2|Bacteria,1ZT3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS3_k127_5624679_4	861299.J421_3088	2.617e-113	384.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GDHHQS3_k127_5624679_2	1392498.JQLH01000001_gene912	3.595e-132	436.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia,2PH19@252356|Maribacter	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_5624679_1	379066.GAU_1447	1.494e-207	662.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_5624679_6	203275.BFO_3114	1.468e-33	140.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,2FR07@200643|Bacteroidia,22WP3@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS3_k127_5625002_2	1312954.KI914854_gene2458	3.762e-110	360.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_5625002_3	266117.Rxyl_0084	9.191e-82	293.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria,4CSVK@84995|Rubrobacteria	84995|Rubrobacteria	P	Mediates zinc uptake. May also transport other divalent cations	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5625002_0	861299.J421_1971	1.426e-177	565.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
GDHHQS3_k127_5625002_1	485918.Cpin_4405	9.697e-155	505.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IVAH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
GDHHQS3_k127_5625002_7	1123508.JH636452_gene6965	1.75e-45	168.0	COG0640@1|root,COG0640@2|Bacteria,2IZUJ@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GDHHQS3_k127_5625002_6	639030.JHVA01000001_gene1931	6.731e-56	205.0	COG3832@1|root,COG3832@2|Bacteria,3Y7X4@57723|Acidobacteria,2JNZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_5625002_5	338969.Rfer_4108	4.118e-72	245.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VSAQ@28216|Betaproteobacteria,4AEGJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GDHHQS3_k127_5625002_4	84531.JMTZ01000031_gene109	9.177e-76	264.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,1T116@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS3_k127_5625002_8	639283.Snov_0503	1.995e-38	152.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,3F0C5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS3_k127_5630444_0	247634.GPB2148_3272	2.644e-16	89.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_5633362_1	1121374.KB891590_gene1663	2.895e-05	55.0	COG2960@1|root,COG2960@2|Bacteria,1NJYD@1224|Proteobacteria,1RYI7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5633362_0	1408473.JHXO01000005_gene1594	6.448e-156	498.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,2FNPT@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
GDHHQS3_k127_5638118_3	1379270.AUXF01000003_gene3462	3.444e-61	216.0	COG3897@1|root,COG3897@2|Bacteria,1ZTUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5638118_0	1379698.RBG1_1C00001G0629	5.911e-209	671.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
GDHHQS3_k127_5638118_1	861299.J421_3930	2.187e-139	456.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS3_k127_5638118_2	861299.J421_3931	1.105e-82	279.0	COG2086@1|root,COG2086@2|Bacteria,1ZT51@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS3_k127_5667874_0	580332.Slit_2920	9.528e-108	354.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,44VJP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_5667874_1	349521.HCH_00659	1.122e-58	214.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S6JM@1236|Gammaproteobacteria,1XMHV@135619|Oceanospirillales	135619|Oceanospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS3_k127_5667874_2	1131553.JIBI01000016_gene604	7.076e-33	127.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,371QW@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
GDHHQS3_k127_5677968_2	861299.J421_3434	1.367e-176	568.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS3_k127_5677968_3	861299.J421_3435	1.825e-112	381.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS3_k127_5677968_0	861299.J421_3436	1.862e-301	935.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GDHHQS3_k127_5677968_4	861299.J421_3437	1.169e-93	319.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_5677968_5	861299.J421_2861	1.03e-89	306.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
GDHHQS3_k127_5677968_1	861299.J421_2862	2.681e-261	811.0	COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS3_k127_5679148_1	56780.SYN_01761	1.954e-06	56.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02246,ko:K08084	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.15.2	-	-	GspH,N_methyl
GDHHQS3_k127_5679148_0	861299.J421_3625	2.948e-10	64.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_5679971_3	1415778.JQMM01000001_gene1965	7.587e-15	83.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,1SBRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
GDHHQS3_k127_5679971_0	1254432.SCE1572_19820	2.058e-153	493.0	COG4864@1|root,COG4864@2|Bacteria,1MWP0@1224|Proteobacteria,42N9I@68525|delta/epsilon subdivisions,2WK7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
GDHHQS3_k127_5679971_1	1254432.SCE1572_19815	1.8e-128	429.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GDHHQS3_k127_5679971_2	1169152.AXVD01000007_gene1893	2.83e-120	399.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,Chlorophyllase2,DLH
GDHHQS3_k127_5690353_1	1267534.KB906755_gene4673	5.132e-11	72.0	COG2273@1|root,COG2273@2|Bacteria,3Y6GF@57723|Acidobacteria,2JKH1@204432|Acidobacteriia	204432|Acidobacteriia	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5690353_3	1227352.C173_05521	1.78e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,1VDV4@1239|Firmicutes,4IPUE@91061|Bacilli,26X10@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5690353_2	317655.Sala_0129	2.542e-10	62.0	COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,2U6HM@28211|Alphaproteobacteria,2K8YU@204457|Sphingomonadales	204457|Sphingomonadales	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5690353_0	1380390.JIAT01000010_gene4381	2.335e-56	203.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4CS3C@84995|Rubrobacteria	84995|Rubrobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GDHHQS3_k127_5704695_3	1123242.JH636438_gene5739	2.168e-27	112.0	COG4122@1|root,COG4122@2|Bacteria,2J0TF@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
GDHHQS3_k127_5704695_1	1133849.O3I_016250	6.47e-74	256.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,4G124@85025|Nocardiaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_5704695_0	861299.J421_2068	1.307e-198	632.0	COG0006@1|root,COG0006@2|Bacteria,1ZSZF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GDHHQS3_k127_5704695_4	234267.Acid_4612	1.192e-23	116.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_5704735_0	379066.GAU_2620	0.0	1166.0	COG1048@1|root,COG1048@2|Bacteria,1ZTE7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_5704735_4	861299.J421_4232	1.754e-48	180.0	COG4420@1|root,COG4420@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS3_k127_5704735_2	861299.J421_4235	2.632e-145	466.0	COG0388@1|root,COG0388@2|Bacteria,1ZTFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GDHHQS3_k127_5704735_1	861299.J421_4236	8.728e-158	513.0	COG2957@1|root,COG2957@2|Bacteria,1ZSZ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
GDHHQS3_k127_5704735_3	861299.J421_4245	1.1e-56	202.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
GDHHQS3_k127_5709155_2	935567.JAES01000004_gene41	9.852e-16	78.0	COG4271@1|root,COG4271@2|Bacteria,1R4Z7@1224|Proteobacteria,1SAF8@1236|Gammaproteobacteria,1X94E@135614|Xanthomonadales	135614|Xanthomonadales	KT	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like,cNMP_binding
GDHHQS3_k127_5709155_0	861299.J421_3829	1.583e-141	461.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
GDHHQS3_k127_5709155_1	1040989.AWZU01000125_gene3972	1.732e-80	270.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
GDHHQS3_k127_5746452_2	861299.J421_2037	9.582e-16	79.0	COG5276@1|root,COG5276@2|Bacteria,1ZUNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS3_k127_5746452_1	392500.Swoo_4759	3.12e-24	112.0	COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,2QB2H@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_5746452_4	379066.GAU_2612	3.48e-06	53.0	2AUA7@1|root,31JXQ@2|Bacteria,1ZV7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5746452_0	497965.Cyan7822_1022	1.702e-97	329.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,3KHGC@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GDHHQS3_k127_5746452_3	861299.J421_1300	1.102e-12	68.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_574715_0	379066.GAU_1585	4.456e-258	816.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_574715_1	861299.J421_3217	1.047e-257	799.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS3_k127_5750003_1	861299.J421_4158	3.16e-173	550.0	COG2804@1|root,COG2804@2|Bacteria,1ZSSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_5750003_4	861299.J421_4159	2.348e-24	108.0	COG1555@1|root,COG1555@2|Bacteria,1ZV96@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS3_k127_5750003_2	379066.GAU_0426	9.944e-80	282.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5750003_3	1434325.AZQN01000003_gene1924	2.519e-56	209.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS3_k127_5750003_0	1379270.AUXF01000001_gene2822	0.0	1753.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_5754061_15	1379270.AUXF01000005_gene449	5.078e-66	228.0	COG0577@1|root,COG0577@2|Bacteria,1ZUCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5754061_10	861299.J421_2896	1.351e-99	329.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_5754061_11	861299.J421_2895	9.414e-93	311.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GDHHQS3_k127_5754061_3	861299.J421_2892	2.047e-179	568.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_5754061_2	861299.J421_2891	1.168e-179	574.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS3_k127_5754061_13	1122605.KB893627_gene2919	6.082e-82	282.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,1IS5S@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS3_k127_5754061_7	1333998.M2A_2344	2.295e-133	437.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5754061_5	1379270.AUXF01000005_gene395	7.974e-161	514.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_5754061_16	861299.J421_2889	8.035e-61	216.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS3_k127_5754061_6	861299.J421_2888	4.284e-155	506.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_5754061_14	379066.GAU_1117	9.133e-79	269.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_5754061_8	379066.GAU_1116	1.659e-121	394.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
GDHHQS3_k127_5754061_17	379066.GAU_1115	1.022e-59	211.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GDHHQS3_k127_5754061_20	1379270.AUXF01000005_gene388	4.762e-18	87.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5754061_12	861299.J421_2883	1.501e-88	295.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GDHHQS3_k127_5754061_18	861299.J421_2882	1.618e-36	140.0	COG0718@1|root,COG0718@2|Bacteria,1ZU1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS3_k127_5754061_4	861299.J421_2881	3.6e-169	545.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS3_k127_5754061_9	861299.J421_2878	2.411e-102	342.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS3_k127_5754061_19	861299.J421_2877	9.571e-32	129.0	COG4980@1|root,COG4980@2|Bacteria,1ZU46@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS3_k127_5754061_1	861299.J421_2876	2.753e-189	603.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_5754061_0	379066.GAU_1107	8.624e-203	640.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
GDHHQS3_k127_5764362_0	379066.GAU_2720	8.034e-102	344.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
GDHHQS3_k127_5764362_1	379066.GAU_2721	2.771e-88	319.0	COG0553@1|root,COG0553@2|Bacteria,1ZUB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
GDHHQS3_k127_5768514_2	1123508.JH636445_gene6811	1.305e-79	285.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
GDHHQS3_k127_5768514_3	1379270.AUXF01000006_gene306	9.464e-52	187.0	COG3880@1|root,COG3880@2|Bacteria,1ZTPQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
GDHHQS3_k127_5768514_1	861299.J421_3214	1.146e-86	302.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GDHHQS3_k127_5768514_0	861299.J421_3213	1.502e-165	532.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5770343_1	861299.J421_3685	8.002e-96	317.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS3_k127_5770343_3	861299.J421_3686	6.279e-65	234.0	COG2755@1|root,COG2755@2|Bacteria,1ZTN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_5770343_2	714943.Mucpa_5289	3.135e-78	276.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1IP20@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5770343_0	1379270.AUXF01000003_gene3738	2.421e-251	803.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5770343_4	861299.J421_1839	8.198e-25	114.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
GDHHQS3_k127_5774049_0	945713.IALB_1183	7.297e-271	866.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
GDHHQS3_k127_5787234_1	383372.Rcas_4246	1.824e-141	461.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,376G5@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS3_k127_5787234_3	1122223.KB890687_gene2443	2.084e-58	204.0	COG0347@1|root,COG0347@2|Bacteria,1WJZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS3_k127_5787234_0	262724.TT_C1950	3.288e-188	595.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS3_k127_5787234_2	760192.Halhy_6459	1.045e-105	358.0	COG1680@1|root,COG1680@2|Bacteria,4PP29@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
GDHHQS3_k127_5792168_3	234267.Acid_7338	1.086e-102	355.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_5792168_1	1121930.AQXG01000011_gene1720	8.692e-176	575.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_5792168_0	861299.J421_1401	3.545e-239	751.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB2	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_5792168_2	861299.J421_6019	4.886e-104	341.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	2|Bacteria	E	Amino acid permease	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
GDHHQS3_k127_5797952_5	1121129.KB903364_gene2954	0.0002263	45.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5797952_4	1122921.KB898209_gene2653	1.242e-05	49.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5797952_0	861299.J421_3205	1.554e-113	375.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GDHHQS3_k127_5797952_3	861299.J421_3206	2.577e-20	97.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
GDHHQS3_k127_5797952_2	1379270.AUXF01000006_gene314	1.026e-59	218.0	COG1159@1|root,COG1159@2|Bacteria,1ZU0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5797952_6	931626.Awo_c04120	0.0006314	45.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,248J3@186801|Clostridia,25Y58@186806|Eubacteriaceae	186801|Clostridia	P	Sodium/calcium exchanger protein	cax	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GDHHQS3_k127_5797952_1	861299.J421_3209	6.849e-69	241.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_5814990_4	358681.BBR47_45300	0.0001812	44.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HABY@91061|Bacilli,26RB0@186822|Paenibacillaceae	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
GDHHQS3_k127_5814990_2	861299.J421_0063	6.812e-103	347.0	COG3842@1|root,COG3842@2|Bacteria,1ZU03@142182|Gemmatimonadetes	2|Bacteria	E	ABC transporter	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_5814990_1	997346.HMPREF9374_2151	4.463e-137	463.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS3_k127_5814990_0	861299.J421_0062	7.964e-173	552.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_5814990_3	861299.J421_3646	1.91e-08	60.0	2ENGP@1|root,33G46@2|Bacteria,1ZU71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS3_k127_5828498_1	886293.Sinac_0412	2.245e-85	294.0	COG3503@1|root,COG3503@2|Bacteria,2J2DR@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GDHHQS3_k127_5828498_0	204669.Acid345_4600	1.26e-86	304.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_5828498_3	861299.J421_3696	6.084e-31	124.0	COG0361@1|root,COG0361@2|Bacteria,1ZV5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS3_k127_5828498_2	861299.J421_1300	1.412e-36	138.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_5831100_5	760192.Halhy_4503	3.879e-25	109.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS3_k127_5831100_4	45157.CMH050CT	2.108e-28	118.0	COG2138@1|root,2RXIW@2759|Eukaryota	2759|Eukaryota	S	sirohydrochlorin cobaltochelatase activity	-	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
GDHHQS3_k127_5831100_0	379066.GAU_0555	4.837e-181	574.0	COG1960@1|root,COG1960@2|Bacteria,1ZT6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_5831100_3	1519464.HY22_05730	7.042e-70	259.0	COG3975@1|root,COG3975@2|Bacteria,1FEP2@1090|Chlorobi	1090|Chlorobi	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
GDHHQS3_k127_5831100_1	1379270.AUXF01000004_gene3355	2.722e-160	515.0	COG1363@1|root,COG1363@2|Bacteria,1ZTF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS3_k127_5831100_2	861299.J421_2445	1.827e-111	371.0	COG0596@1|root,COG0596@2|Bacteria,1ZTAV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
GDHHQS3_k127_5844944_3	1223410.KN050846_gene73	0.0005063	50.0	2EKX6@1|root,33EKQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5844944_1	861299.J421_0407	1.007e-41	159.0	COG3278@1|root,COG3278@2|Bacteria,1ZU6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
GDHHQS3_k127_5844944_2	1379270.AUXF01000001_gene2572	4.56e-26	119.0	COG0589@1|root,COG0589@2|Bacteria,1ZUMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_5844944_0	663610.JQKO01000009_gene477	5.487e-230	723.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3NAVA@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
GDHHQS3_k127_5859745_1	379066.GAU_3166	5.019e-23	104.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS3_k127_5859745_0	2880.D7G6W2	6.962e-28	131.0	COG0457@1|root,KOG4658@1|root,KOG1840@2759|Eukaryota,KOG4658@2759|Eukaryota	2759|Eukaryota	S	ADP binding	-	-	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_16,TPR_4,TPR_7,TPR_8
GDHHQS3_k127_5859745_4	1121405.dsmv_2486	0.0009345	52.0	COG0810@1|root,COG0810@2|Bacteria,1Q1IC@1224|Proteobacteria,437A9@68525|delta/epsilon subdivisions,2X24K@28221|Deltaproteobacteria,2MP57@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_5859745_2	375286.mma_2474	2.327e-10	73.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria,475YZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular repeat, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
GDHHQS3_k127_5866003_0	861299.J421_3780	0.0	1070.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS3_k127_5866003_1	221288.JH992901_gene4730	4.138e-76	263.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1JJTN@1189|Stigonemataceae	1117|Cyanobacteria	S	short chain dehydrogenase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS3_k127_5866003_2	861299.J421_2120	2.411e-52	187.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	eaeH	GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Amidase_2,Big_1,CW_7,DUF1529,DUF928,IAT_beta,Invasin_D3,LysM
GDHHQS3_k127_5869863_5	861299.J421_2679	3.365e-37	140.0	COG4608@1|root,COG4608@2|Bacteria,1ZSTB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_5869863_0	861299.J421_2678	6.604e-204	647.0	COG3104@1|root,COG3104@2|Bacteria,1ZSRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GDHHQS3_k127_5869863_6	1090319.KE386571_gene2121	3.027e-25	114.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_5869863_1	861299.J421_2677	9.647e-133	443.0	COG4775@1|root,COG4775@2|Bacteria,1ZTG1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5869863_4	1303518.CCALI_01736	5.734e-53	196.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS3_k127_5869863_3	1125863.JAFN01000001_gene535	9.85e-57	212.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_5869863_2	861299.J421_2674	7.269e-79	269.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
GDHHQS3_k127_5870628_1	1278073.MYSTI_04691	2.834e-157	515.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS3_k127_5870628_8	498848.TaqDRAFT_5116	6.907e-34	135.0	COG2332@1|root,COG2332@2|Bacteria,1WJVR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GDHHQS3_k127_5870628_4	1144275.COCOR_03000	3.316e-58	210.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS3_k127_5870628_7	649638.Trad_0418	3.876e-37	152.0	COG2386@1|root,COG2386@2|Bacteria,1WIH9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ABC-type transport system involved in cytochrome c biogenesis permease component	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS3_k127_5870628_5	479434.Sthe_1412	7.083e-45	171.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS3_k127_5870628_12	861299.J421_5746	1.704e-23	109.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_5870628_2	1288963.ADIS_2413	1.211e-144	479.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47N8C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5870628_9	379066.GAU_2093	7.843e-34	143.0	COG3467@1|root,COG3467@2|Bacteria,1ZU4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS3_k127_5870628_14	936455.KI421499_gene1793	3.192e-05	55.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,3JYKK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS3_k127_5870628_11	1379270.AUXF01000007_gene905	6.352e-31	134.0	COG0589@1|root,COG0589@2|Bacteria,1ZUGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335,Usp
GDHHQS3_k127_5870628_0	1379270.AUXF01000003_gene3360	4.427e-158	522.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	2|Bacteria	P	E1-E2 ATPase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
GDHHQS3_k127_5870628_6	765420.OSCT_0546	1.718e-37	154.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_5870628_10	379066.GAU_2093	1.377e-33	138.0	COG3467@1|root,COG3467@2|Bacteria,1ZU4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS3_k127_5870628_13	497965.Cyan7822_5120	1.901e-07	57.0	2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria,3KIS1@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5870628_3	1254432.SCE1572_02705	2.021e-70	248.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria,2YW9J@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA
GDHHQS3_k127_5877303_14	665029.EAMY_0593	4.066e-20	94.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,1S2RK@1236|Gammaproteobacteria,3X4SN@551|Erwinia	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_5877303_16	653733.Selin_0316	1.454e-10	70.0	COG4944@1|root,COG4944@2|Bacteria	2|Bacteria	K	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
GDHHQS3_k127_5877303_0	243090.RB9570	6.072e-169	549.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,2IYEC@203682|Planctomycetes	203682|Planctomycetes	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
GDHHQS3_k127_5877303_10	1122939.ATUD01000015_gene1011	3.958e-50	186.0	COG2128@1|root,COG2128@2|Bacteria,2IHW3@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_5877303_3	743719.PaelaDRAFT_1947	3.032e-113	368.0	COG4977@1|root,COG4977@2|Bacteria,1VRXB@1239|Firmicutes,4HUFN@91061|Bacilli,26WGW@186822|Paenibacillaceae	91061|Bacilli	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
GDHHQS3_k127_5877303_6	1379270.AUXF01000001_gene2842	4.346e-62	220.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GDHHQS3_k127_5877303_11	1380394.JADL01000002_gene1385	3.775e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria,2JX2Z@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5877303_12	1243664.CAVL020000032_gene2882	1.159e-44	175.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Lipocalin_2,NAD_binding_10
GDHHQS3_k127_5877303_9	502025.Hoch_6301	6.422e-51	186.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,42S5Q@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
GDHHQS3_k127_5877303_4	479434.Sthe_0485	1.188e-107	377.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
GDHHQS3_k127_5877303_1	518766.Rmar_0538	1.132e-120	395.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
GDHHQS3_k127_5877303_8	1384054.N790_00725	1.579e-53	195.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1X631@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS3_k127_5877303_17	1121456.ATVA01000012_gene2670	9.215e-10	70.0	COG3794@1|root,COG3794@2|Bacteria,1N3IJ@1224|Proteobacteria,42TYB@68525|delta/epsilon subdivisions,2WR42@28221|Deltaproteobacteria,2MCVC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
GDHHQS3_k127_5877303_15	1121439.dsat_2146	4.2e-12	76.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria,42UUQ@68525|delta/epsilon subdivisions,2WQGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5877303_13	530564.Psta_1991	8.606e-27	115.0	2E5ES@1|root,3306N@2|Bacteria,2J0XS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5877303_5	479434.Sthe_0485	4.903e-104	367.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
GDHHQS3_k127_5887488_5	861299.J421_4386	4.983e-93	308.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS3_k127_5887488_4	661478.OP10G_3097	5.007e-116	389.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
GDHHQS3_k127_5887488_1	861299.J421_1994	6.924e-187	601.0	COG2989@1|root,COG2989@2|Bacteria,1ZUAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative peptidoglycan binding domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GDHHQS3_k127_5887488_0	861299.J421_1043	6.889e-230	722.0	COG0467@1|root,COG0467@2|Bacteria,1ZUWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS3_k127_5887488_2	861299.J421_1044	6.592e-175	568.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1044|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5887488_9	204669.Acid345_0673	6.165e-06	53.0	2C5W2@1|root,33IGR@2|Bacteria,3Y8EW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5887488_3	1500893.JQNB01000001_gene659	2.971e-117	387.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1X4C8@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_5887488_7	484019.THA_846	8.94e-81	292.0	COG0395@1|root,COG0395@2|Bacteria,2GCIV@200918|Thermotogae	200918|Thermotogae	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_5887488_6	580331.Thit_0425	6.815e-92	311.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
GDHHQS3_k127_5887488_8	1462526.BN990_00733	5.296e-17	87.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli,4C6FD@84406|Virgibacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
GDHHQS3_k127_5890175_9	861299.J421_2812	2.871e-45	167.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
GDHHQS3_k127_5890175_8	1128421.JAGA01000002_gene1381	1.726e-105	357.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
GDHHQS3_k127_5890175_2	945713.IALB_0608	6.141e-168	552.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
GDHHQS3_k127_5890175_11	861299.J421_2817	3.725e-27	113.0	2FC5K@1|root,3449E@2|Bacteria,1ZU4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5890175_12	379066.GAU_0914	1.799e-15	82.0	2C3VP@1|root,2ZRAS@2|Bacteria,1ZU7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5890175_3	861299.J421_2819	6.441e-142	459.0	COG0123@1|root,COG0123@2|Bacteria,1ZSKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS3_k127_5890175_6	379066.GAU_0922	7.635e-116	383.0	COG0598@1|root,COG0598@2|Bacteria,1ZSKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS3_k127_5890175_7	861299.J421_2823	2.259e-114	377.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_5890175_5	861299.J421_2824	4.864e-122	400.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_5890175_1	574087.Acear_1443	2.219e-169	559.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WACI@53433|Halanaerobiales	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS3_k127_5890175_4	1379270.AUXF01000002_gene1601	2.597e-135	446.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
GDHHQS3_k127_5890175_0	1144275.COCOR_00398	1.185e-188	594.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
GDHHQS3_k127_5892460_2	861299.J421_3554	1.15e-83	283.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS3_k127_5892460_4	379066.GAU_1944	5.006e-50	181.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_5892460_3	861299.J421_3552	3.109e-54	199.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
GDHHQS3_k127_5892460_0	861299.J421_3551	5.453e-118	393.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_5892460_5	379066.GAU_1940	8.396e-38	152.0	COG1729@1|root,COG1729@2|Bacteria,1ZTU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
GDHHQS3_k127_5892460_1	861299.J421_3548	1.117e-91	308.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS3_k127_5907168_6	861299.J421_3306	3.196e-163	518.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS3_k127_5907168_16	861299.J421_3305	4.665e-50	180.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS3_k127_5907168_21	621372.ACIH01000258_gene4297	1.625e-07	56.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,26TH1@186822|Paenibacillaceae	91061|Bacilli	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS3_k127_5907168_18	1379270.AUXF01000006_gene219	3.196e-40	153.0	COG0314@1|root,COG0314@2|Bacteria,1ZU08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
GDHHQS3_k127_5907168_7	1379270.AUXF01000006_gene220	7.024e-145	466.0	COG2896@1|root,COG2896@2|Bacteria,1ZSMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GDHHQS3_k127_5907168_5	861299.J421_3301	7.009e-165	523.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS3_k127_5907168_15	861299.J421_3300	3.534e-62	220.0	2CAZH@1|root,2Z7RU@2|Bacteria,1ZTQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
GDHHQS3_k127_5907168_0	1128421.JAGA01000003_gene2923	0.0	1067.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_5907168_8	861299.J421_3298	1.964e-120	392.0	COG0479@1|root,COG0479@2|Bacteria,1ZT02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS3_k127_5907168_12	379066.GAU_1663	6.578e-100	330.0	COG0717@1|root,COG0717@2|Bacteria,1ZSN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS3_k127_5907168_20	497964.CfE428DRAFT_4575	5.588e-13	74.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS3_k127_5907168_10	1379270.AUXF01000006_gene230	2.906e-106	348.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_5907168_11	861299.J421_3293	1.343e-101	339.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS3_k127_5907168_1	861299.J421_3292	3.387e-239	744.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_5907168_14	1379270.AUXF01000006_gene233	5.998e-78	270.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS3_k127_5907168_3	379066.GAU_1657	2.668e-224	703.0	COG1894@1|root,COG1894@2|Bacteria,1ZSQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_5907168_2	861299.J421_3289	8.822e-232	728.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1ZTDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GDHHQS3_k127_5907168_4	861299.J421_3288	3.462e-173	552.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_5907168_13	861299.J421_3287	3.417e-92	304.0	COG1143@1|root,COG1143@2|Bacteria,1ZTHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
GDHHQS3_k127_5907168_17	1379270.AUXF01000006_gene238	4.054e-47	175.0	COG0839@1|root,COG0839@2|Bacteria,1ZTSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_5907168_19	1379270.AUXF01000006_gene239	1.505e-29	121.0	COG0713@1|root,COG0713@2|Bacteria,1ZU00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS3_k127_5907168_9	861299.J421_3284	1.465e-110	370.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_5909496_1	861299.J421_2415	6.937e-225	710.0	COG1027@1|root,COG1027@2|Bacteria,1ZT1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
GDHHQS3_k127_5909496_3	1166018.FAES_1629	2.228e-116	387.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
GDHHQS3_k127_5909496_2	861299.J421_2417	2.831e-139	452.0	COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
GDHHQS3_k127_5909496_4	1123239.KB898625_gene336	1.413e-23	115.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	mcpB1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
GDHHQS3_k127_5909496_0	379066.GAU_0518	0.0	1213.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_5928233_5	555779.Dthio_PD1047	3.566e-24	102.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2M8NG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GDHHQS3_k127_5928233_3	1267535.KB906767_gene2008	5.462e-109	364.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria,2JMFW@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS3_k127_5928233_0	234267.Acid_5518	0.0	1275.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS3_k127_5928233_2	1267535.KB906767_gene2010	3.695e-115	387.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria,2JK7S@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_5928233_4	1121405.dsmv_0268	3.709e-33	133.0	COG1695@1|root,COG1695@2|Bacteria,1RHG3@1224|Proteobacteria,42UV3@68525|delta/epsilon subdivisions,2WR1W@28221|Deltaproteobacteria,2MNUT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_5928233_1	292415.Tbd_1072	4.179e-287	896.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
GDHHQS3_k127_5952898_0	330214.NIDE1574	8.252e-120	392.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
GDHHQS3_k127_5952898_1	1408254.T458_14190	1.506e-78	276.0	COG0327@1|root,COG0327@2|Bacteria,1V149@1239|Firmicutes,4HUDB@91061|Bacilli,26WAK@186822|Paenibacillaceae	91061|Bacilli	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
GDHHQS3_k127_5952898_2	571166.KI421509_gene2039	9.657e-12	66.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_5967323_4	379066.GAU_1889	6.391e-28	116.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_5967323_3	1379270.AUXF01000006_gene70	2.896e-40	158.0	COG1579@1|root,COG1579@2|Bacteria,1ZU01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_5967323_1	338963.Pcar_2679	2.889e-87	315.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS3_k127_5967323_0	861299.J421_3463	5.878e-287	901.0	COG1193@1|root,COG1193@2|Bacteria,1ZSWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS3_k127_5967323_2	861299.J421_3464	7.65e-56	198.0	COG1610@1|root,COG1610@2|Bacteria,1ZTS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS3_k127_5967323_5	379066.GAU_1894	1.197e-26	109.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS3_k127_5969929_3	861299.J421_3898	3.106e-05	49.0	COG0151@1|root,COG0151@2|Bacteria,1ZSY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
GDHHQS3_k127_5969929_1	861299.J421_3896	1.994e-196	619.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_5969929_0	861299.J421_3894	7.036e-208	657.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_5969929_2	379066.GAU_2427	3.148e-134	437.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS3_k127_6011593_4	278963.ATWD01000001_gene4215	1.77e-52	211.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_6011593_2	234267.Acid_3095	1.695e-95	322.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
GDHHQS3_k127_6011593_1	278963.ATWD01000001_gene3334	1.572e-124	406.0	COG0327@1|root,COG0327@2|Bacteria,3Y65N@57723|Acidobacteria	57723|Acidobacteria	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
GDHHQS3_k127_6011593_3	278963.ATWD01000001_gene3335	1.45e-94	318.0	COG0327@1|root,COG0327@2|Bacteria,3Y6HX@57723|Acidobacteria	57723|Acidobacteria	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
GDHHQS3_k127_6011593_0	1089551.KE386572_gene4473	9.224e-166	525.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,1MUET@1224|Proteobacteria,2TQMZ@28211|Alphaproteobacteria,4BPQ8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Rubrerythrin	mbfA	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GDHHQS3_k127_6015353_8	247633.GP2143_17791	9.192e-66	228.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6015353_9	247633.GP2143_18126	5.832e-55	204.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6015353_10	247633.GP2143_17796	8.12e-52	195.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6015353_1	1123248.KB893359_gene2156	3.159e-246	797.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,4NGAU@976|Bacteroidetes,1IWXQ@117747|Sphingobacteriia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS3_k127_6015353_4	1340493.JNIF01000004_gene17	4.217e-116	404.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_6015353_7	1121904.ARBP01000012_gene1301	2.004e-84	309.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6015353_3	1288963.ADIS_3302	2.225e-135	447.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,47VT1@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS3_k127_6015353_2	1267535.KB906767_gene4072	1.729e-190	599.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_6015353_6	234267.Acid_2075	9.246e-85	298.0	COG3356@1|root,COG3356@2|Bacteria,3Y5I7@57723|Acidobacteria	57723|Acidobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
GDHHQS3_k127_6015353_5	1217720.ALOX01000059_gene2794	1.392e-87	306.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,2JRF4@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_6015353_0	234267.Acid_6871	0.0	1191.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_6015353_11	234267.Acid_0644	8.885e-39	157.0	COG3464@1|root,COG3464@2|Bacteria	234267.Acid_0644|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6040560_2	861299.J421_4248	7.429e-98	324.0	COG0603@1|root,COG0603@2|Bacteria,1ZT7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS3_k127_6040560_1	861299.J421_4249	1.396e-98	327.0	COG0602@1|root,COG0602@2|Bacteria,1ZT5J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	-
GDHHQS3_k127_6040560_0	1128421.JAGA01000003_gene2811	1.51e-148	481.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_6041606_0	861299.J421_2504	2.238e-220	692.0	COG0372@1|root,COG0372@2|Bacteria,1ZT4W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS3_k127_6041606_1	1146883.BLASA_1778	6.812e-173	553.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EVYU@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GDHHQS3_k127_6048483_2	861299.J421_2376	8.308e-17	82.0	COG0380@1|root,COG0380@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
GDHHQS3_k127_6048483_1	1267533.KB906738_gene2352	6.466e-18	91.0	COG0380@1|root,COG0380@2|Bacteria,3Y3X7@57723|Acidobacteria,2JKGZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20
GDHHQS3_k127_6048483_0	1340493.JNIF01000003_gene2166	5.526e-263	834.0	COG1629@1|root,COG4771@2|Bacteria,3Y36T@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS3_k127_6060860_0	861299.J421_1135	1.585e-275	857.0	COG2303@1|root,COG2303@2|Bacteria,1ZTG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_6060860_5	926549.KI421517_gene3612	2.616e-54	201.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,47MR9@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS3_k127_6060860_2	861299.J421_1132	1.604e-197	622.0	COG0673@1|root,COG0673@2|Bacteria,1ZSVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_6060860_10	1379270.AUXF01000003_gene3750	0.0009642	46.0	COG1629@1|root,COG4219@1|root,COG1629@2|Bacteria,COG4219@2|Bacteria,1ZUHU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KPT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
GDHHQS3_k127_6060860_9	661478.OP10G_1457	6.442e-25	110.0	COG3668@1|root,32ZH9@2|Bacteria	2|Bacteria	S	COG3668 Plasmid stabilization system protein	osmB	-	-	-	-	-	-	-	-	-	-	-	Rho_N
GDHHQS3_k127_6060860_1	443144.GM21_2279	3.995e-232	750.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,42M4M@68525|delta/epsilon subdivisions,2WIPI@28221|Deltaproteobacteria,43SU8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS3_k127_6060860_4	1121920.AUAU01000004_gene852	1.63e-61	224.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria	57723|Acidobacteria	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS3_k127_6060860_6	1278073.MYSTI_01758	3.514e-49	194.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
GDHHQS3_k127_6060860_3	414684.RC1_3385	1.265e-78	268.0	COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,2U5E8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS3_k127_6060860_8	861299.J421_4416	4.659e-29	119.0	COG2261@1|root,COG2261@2|Bacteria,1ZV7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_6060860_7	469383.Cwoe_3468	1.044e-37	148.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052,OmdA
GDHHQS3_k127_6063347_1	861299.J421_2523	2.28e-177	565.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
GDHHQS3_k127_6063347_2	861299.J421_2520	1.855e-88	302.0	COG0354@1|root,COG0354@2|Bacteria,1ZTMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_6063347_0	861299.J421_2518	3.935e-240	749.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_6063347_3	204669.Acid345_3903	2.882e-18	90.0	COG1102@1|root,COG1102@2|Bacteria,3Y50F@57723|Acidobacteria,2JKKJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
GDHHQS3_k127_6118612_1	56107.Cylst_2378	7.583e-38	152.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1HIHD@1161|Nostocales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Cadherin,Calx-beta,DUF4347,HemolysinCabind,Lectin_C
GDHHQS3_k127_6118612_0	338969.Rfer_0625	4.253e-46	172.0	2DMT2@1|root,32TGY@2|Bacteria,1R3E1@1224|Proteobacteria,2VUA9@28216|Betaproteobacteria,4AJBF@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6118612_2	547163.BN979_02517	1.67e-16	86.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,233HY@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
GDHHQS3_k127_6118650_1	861299.J421_3743	9.154e-172	555.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_6118650_0	379066.GAU_1084	6.359e-179	569.0	COG0477@1|root,COG2814@2|Bacteria,1ZTDQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
GDHHQS3_k127_6118650_2	861299.J421_1130	2.246e-20	91.0	COG2133@1|root,COG2133@2|Bacteria,1ZTW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS3_k127_6119018_2	886379.AEWI01000122_gene1854	2.444e-42	168.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,2FRKB@200643|Bacteroidia,3XJYA@558415|Marinilabiliaceae	976|Bacteroidetes	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
GDHHQS3_k127_6119018_1	861299.J421_3450	8.121e-83	289.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
GDHHQS3_k127_6119018_0	861299.J421_3449	2.279e-91	319.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_6157769_1	861299.J421_3649	1.446e-110	365.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_6157769_0	861299.J421_3650	2.695e-128	421.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_6157769_2	1122137.AQXF01000004_gene1587	5.221e-36	148.0	COG2267@1|root,COG2267@2|Bacteria,1QWE3@1224|Proteobacteria,2UDWQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_6157769_3	1379270.AUXF01000002_gene1567	1.89e-06	50.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_6172387_1	1207076.ALAT01000036_gene4196	7.138e-25	115.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1Z1YQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_6172387_2	1173020.Cha6605_5799	1.65e-18	89.0	COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
GDHHQS3_k127_6172387_3	366602.Caul_4862	1.037e-11	72.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2U9KN@28211|Alphaproteobacteria,2KHF8@204458|Caulobacterales	204458|Caulobacterales	K	transcription regulator containing HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS3_k127_6172387_0	861299.J421_2988	3.487e-267	839.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6288691_5	379066.GAU_0437	1.136e-53	197.0	COG0124@1|root,COG0124@2|Bacteria,1ZTTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6288691_1	118163.Ple7327_0424	1.897e-171	550.0	COG0179@1|root,COG0179@2|Bacteria,1G2C6@1117|Cyanobacteria,3VHWU@52604|Pleurocapsales	1117|Cyanobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
GDHHQS3_k127_6288691_4	215803.DB30_3560	4.046e-54	194.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,438IX@68525|delta/epsilon subdivisions,2X3TU@28221|Deltaproteobacteria,2YX3A@29|Myxococcales	28221|Deltaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS3_k127_6288691_0	1227739.Hsw_0942	4.53e-215	687.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
GDHHQS3_k127_6288691_8	861299.J421_3698	2.391e-47	176.0	COG2967@1|root,COG2967@2|Bacteria,1ZTR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
GDHHQS3_k127_6288691_6	443144.GM21_3621	1.055e-52	195.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GDHHQS3_k127_6288691_10	319795.Dgeo_1667	1.478e-42	168.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS3_k127_6288691_3	479434.Sthe_2435	1.702e-120	393.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS3_k127_6288691_2	316274.Haur_3021	1.415e-164	536.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS3_k127_6288691_9	309801.trd_1531	8.027e-43	178.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
GDHHQS3_k127_6288691_7	861299.J421_3040	2.825e-52	192.0	COG0037@1|root,COG0037@2|Bacteria,1ZTK2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
GDHHQS3_k127_6296686_10	861299.J421_3554	0.0004308	46.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS3_k127_6296686_1	379066.GAU_1946	1.23e-127	417.0	COG1087@1|root,COG1087@2|Bacteria,1ZSX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_6296686_2	644966.Tmar_1263	4.868e-90	312.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS3_k127_6296686_7	326427.Cagg_1264	1.201e-25	117.0	COG1010@1|root,COG1648@1|root,COG2073@1|root,COG1010@2|Bacteria,COG1648@2|Bacteria,COG2073@2|Bacteria,2G7UU@200795|Chloroflexi,376JW@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	1.3.1.76,2.1.1.131,3.7.1.12,4.99.1.4	ko:K02304,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05180,R05809,R07772	RC00003,RC01012,RC01034,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid,NAD_binding_7,TP_methylase
GDHHQS3_k127_6296686_8	1125863.JAFN01000001_gene1124	2.257e-21	104.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS3_k127_6296686_9	1122603.ATVI01000006_gene615	2.761e-13	82.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1X3I7@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS3_k127_6296686_3	861299.J421_3557	1.888e-66	231.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS3_k127_6296686_6	861299.J421_3558	2.697e-32	134.0	COG0454@1|root,COG0456@2|Bacteria,1ZU09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS3_k127_6296686_5	861299.J421_3559	3.615e-35	143.0	COG1214@1|root,COG1214@2|Bacteria,1ZU16@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_6296686_4	861299.J421_3560	2.861e-57	203.0	COG0802@1|root,COG0802@2|Bacteria,1ZTY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
GDHHQS3_k127_6296686_0	861299.J421_3561	3.832e-218	683.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS3_k127_6539403_0	861299.J421_3701	1.479e-157	509.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_6539403_2	861299.J421_2983	1.837e-84	284.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS3_k127_6539403_1	379066.GAU_1256	1.92e-105	347.0	COG1199@1|root,COG1199@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
GDHHQS3_k127_657840_7	861299.J421_3123	1.031e-30	129.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
GDHHQS3_k127_657840_8	861299.J421_3122	1.121e-28	120.0	COG2893@1|root,COG2893@2|Bacteria,1ZU41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
GDHHQS3_k127_657840_2	379066.GAU_1477	2.274e-131	429.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
GDHHQS3_k127_657840_1	861299.J421_3119	1.005e-156	503.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_657840_6	861299.J421_3118	3.131e-51	188.0	COG0781@1|root,COG0781@2|Bacteria,1ZTRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS3_k127_657840_5	861299.J421_3117	1.616e-61	215.0	COG0054@1|root,COG0054@2|Bacteria,1ZTPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS3_k127_657840_0	861299.J421_3116	3.171e-197	624.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GDHHQS3_k127_657840_3	1379270.AUXF01000005_gene724	1.796e-74	255.0	COG0307@1|root,COG0307@2|Bacteria,1ZTQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS3_k127_657840_4	861299.J421_3114	5.501e-74	258.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS3_k127_6653295_4	379066.GAU_3334	2.727e-25	108.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_6653295_0	861299.J421_1931	1.068e-211	669.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_6653295_2	861299.J421_1849	1.579e-102	343.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_6653295_5	593907.Celgi_0128	4.684e-08	57.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_6653295_3	1242864.D187_005528	1.239e-99	342.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6653295_1	1267535.KB906767_gene244	2.17e-170	544.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria,2JHMU@204432|Acidobacteriia	204432|Acidobacteriia	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GDHHQS3_k127_6748671_1	861299.J421_2683	7.38e-156	509.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_6748671_4	330214.NIDE4014	3.544e-42	172.0	2EUIU@1|root,33N0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6748671_3	861299.J421_0834	7.731e-87	299.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	MA20_24580	-	-	-	-	-	-	-	-	-	-	-	FMN_red
GDHHQS3_k127_6748671_2	1242864.D187_002504	5.729e-117	383.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_6748671_5	861299.J421_1299	5.499e-28	121.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
GDHHQS3_k127_6748671_0	1379270.AUXF01000001_gene2826	1.89e-185	586.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS3_k127_6754345_2	266117.Rxyl_1977	1.341e-57	211.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
GDHHQS3_k127_6754345_0	1303518.CCALI_01058	1.411e-148	480.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GDHHQS3_k127_6754345_1	861299.J421_4190	6.033e-70	246.0	COG0755@1|root,COG0755@2|Bacteria,1ZTJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS3_k127_6754345_3	861299.J421_4191	2.256e-36	140.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS3_k127_6757855_0	861299.J421_6256	2.716e-65	253.0	COG0515@1|root,COG0515@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
GDHHQS3_k127_6757855_1	861299.J421_0886	5.684e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,1ZUWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS3_k127_6774288_4	861299.J421_2344	2.918e-12	70.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_6774288_0	861299.J421_2352	3.518e-197	623.0	COG4102@1|root,COG4102@2|Bacteria,1ZSZ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS3_k127_6774288_1	861299.J421_2353	4.135e-190	611.0	COG5267@1|root,COG5267@2|Bacteria,1ZSPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS3_k127_6774288_2	379066.GAU_0674	1.933e-109	372.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUFI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_6774288_3	1254432.SCE1572_17210	8.817e-17	81.0	COG0454@1|root,COG0454@2|Bacteria,1QZHM@1224|Proteobacteria,43CIQ@68525|delta/epsilon subdivisions,2WWHV@28221|Deltaproteobacteria,2Z207@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_6775410_1	861299.J421_2387	4.666e-46	168.0	COG1680@1|root,COG1680@2|Bacteria,1ZV34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_6775410_2	861299.J421_0306	5.105e-24	116.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_6775410_0	264198.Reut_B3494	3.133e-200	636.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria,1K08R@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_6789822_0	313612.L8106_25150	3.926e-106	350.0	COG0754@1|root,COG0754@2|Bacteria,1G4ND@1117|Cyanobacteria,1H9K0@1150|Oscillatoriales	1117|Cyanobacteria	E	Glutathionylspermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
GDHHQS3_k127_6789822_3	1129374.AJE_08622	4.107e-34	137.0	COG3766@1|root,COG3766@2|Bacteria,1N14W@1224|Proteobacteria,1S818@1236|Gammaproteobacteria,46CEJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
GDHHQS3_k127_6789822_2	671143.DAMO_2071	4.753e-66	233.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	DUF429,RelA_SpoT
GDHHQS3_k127_6789822_1	864051.BurJ1DRAFT_3907	2.051e-102	336.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,1KJMV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
GDHHQS3_k127_6804674_8	479434.Sthe_0634	1.164e-47	178.0	COG5483@1|root,COG5483@2|Bacteria,2G8NZ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GDHHQS3_k127_6804674_4	861299.J421_2858	4.896e-113	376.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS3_k127_6804674_6	379066.GAU_2047	1.445e-71	248.0	COG0586@1|root,COG0586@2|Bacteria,1ZTJB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS3_k127_6804674_5	379066.GAU_2048	2.238e-101	333.0	COG0605@1|root,COG0605@2|Bacteria,1ZT7S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS3_k127_6804674_0	861299.J421_3647	3.04e-321	993.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GDHHQS3_k127_6804674_7	1297742.A176_03628	1.467e-69	240.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
GDHHQS3_k127_6804674_2	404589.Anae109_3607	2.646e-154	496.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS3_k127_6804674_3	861299.J421_3021	3e-149	486.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1ZT0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
GDHHQS3_k127_6804674_1	234267.Acid_4487	1.249e-213	682.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_6805672_2	1449049.JONW01000009_gene4446	2.287e-38	149.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2UI5V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_6805672_3	661478.OP10G_4086	1.292e-07	64.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,TraB
GDHHQS3_k127_6805672_0	861299.J421_6339	3.401e-271	847.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
GDHHQS3_k127_6805672_1	204669.Acid345_2620	5.848e-124	411.0	COG0773@1|root,COG0773@2|Bacteria,3Y2M2@57723|Acidobacteria,2JIE2@204432|Acidobacteriia	204432|Acidobacteriia	M	Mur ligase middle domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_6824529_0	1379270.AUXF01000003_gene3729	4.986e-121	389.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS3_k127_6824529_1	379066.GAU_2126	1.197e-120	400.0	COG0365@1|root,COG0365@2|Bacteria,1ZSSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_6837079_0	926569.ANT_18930	2.679e-26	124.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
GDHHQS3_k127_6855051_7	861299.J421_2837	2.095e-23	104.0	COG0405@1|root,COG0405@2|Bacteria,1ZT0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_6855051_8	1379270.AUXF01000004_gene2960	1.634e-18	94.0	2BBF1@1|root,324YA@2|Bacteria,1ZUV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6855051_3	861299.J421_2838	5.515e-118	388.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_6855051_2	861299.J421_2839	9.059e-149	479.0	COG2377@1|root,COG2377@2|Bacteria,1ZSZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
GDHHQS3_k127_6855051_5	1379270.AUXF01000004_gene2957	9.151e-115	390.0	COG1472@1|root,COG1472@2|Bacteria,1ZST8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3
GDHHQS3_k127_6855051_1	1173027.Mic7113_3322	4.623e-161	518.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1H9RK@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
GDHHQS3_k127_6855051_6	1379270.AUXF01000004_gene2956	2.837e-63	227.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_6855051_4	861299.J421_2844	6.91e-117	396.0	COG0860@1|root,COG0860@2|Bacteria,1ZT6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS3_k127_6855051_0	861299.J421_2845	4.774e-273	873.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSWP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_6855051_9	379066.GAU_0942	8.464e-16	78.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
GDHHQS3_k127_6888829_3	1123277.KB893179_gene3194	3.292e-63	225.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,47N0P@768503|Cytophagia	976|Bacteroidetes	O	proteinase inhibitor I4 serpin	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS3_k127_6888829_1	861299.J421_3092	3.294e-102	342.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
GDHHQS3_k127_6888829_2	379066.GAU_1449	2.931e-76	269.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS3_k127_6888829_0	861299.J421_3094	2.252e-144	464.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
GDHHQS3_k127_6899842_7	861299.J421_1197	3.701e-84	281.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
GDHHQS3_k127_6899842_3	861299.J421_0375	2.55e-164	526.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
GDHHQS3_k127_6899842_6	861299.J421_5597	1.085e-87	305.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
GDHHQS3_k127_6899842_1	861299.J421_1624	5.005e-196	619.0	COG0673@1|root,COG0673@2|Bacteria,1ZSW3@142182|Gemmatimonadetes	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_6899842_0	518766.Rmar_2303	1.251e-200	638.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes	976|Bacteroidetes	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
GDHHQS3_k127_6899842_4	861299.J421_5614	6.018e-111	365.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GDHHQS3_k127_6899842_5	861299.J421_2721	1.168e-88	314.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_2721|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6899842_2	1123508.JH636440_gene2636	1.858e-175	563.0	COG0467@1|root,COG0467@2|Bacteria,2IZBF@203682|Planctomycetes	203682|Planctomycetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS3_k127_6904573_0	1128421.JAGA01000002_gene905	1.219e-111	368.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
GDHHQS3_k127_6904573_1	1297742.A176_01806	6.75e-108	360.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6904573_2	861299.J421_0105	2.858e-32	131.0	28NRS@1|root,2ZBQZ@2|Bacteria,1ZV13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6906749_1	861299.J421_6097	5.792e-39	157.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14,Peptidase_M56
GDHHQS3_k127_6906749_5	861299.J421_4079	6.243e-13	78.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_4079|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS3_k127_6906749_0	1379270.AUXF01000007_gene888	6.098e-158	509.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS3_k127_6906749_2	379066.GAU_0704	3.521e-31	124.0	COG0639@1|root,COG0639@2|Bacteria,1ZUFY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS3_k127_6908142_1	945713.IALB_0512	2.308e-89	301.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GDHHQS3_k127_6908142_2	1094980.Mpsy_0125	2.628e-21	109.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,2N9YH@224756|Methanomicrobia	224756|Methanomicrobia	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6908142_0	861299.J421_1019	1.484e-106	350.0	COG1402@1|root,COG1402@2|Bacteria,1ZTKC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS3_k127_6909718_0	861299.J421_3938	0.0	1028.0	COG1966@1|root,COG1966@2|Bacteria,1ZSWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
GDHHQS3_k127_6909718_2	1379270.AUXF01000007_gene855	4.292e-60	216.0	2C4IX@1|root,32RE1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_6909718_1	1379270.AUXF01000003_gene3439	1.791e-273	873.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
GDHHQS3_k127_6909718_3	861299.J421_3939	2.801e-11	65.0	COG2879@1|root,COG2879@2|Bacteria,1ZU6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
GDHHQS3_k127_6912353_13	118168.MC7420_1914	7.57e-17	95.0	2DRBA@1|root,33B2N@2|Bacteria,1GAYX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6912353_11	1185652.USDA257_c53240	3.706e-22	113.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,4B8S4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GlcNAc transferase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
GDHHQS3_k127_6912353_15	269799.Gmet_0284	4.461e-14	86.0	COG4319@1|root,COG4319@2|Bacteria,1P8UQ@1224|Proteobacteria,43384@68525|delta/epsilon subdivisions,2WY2X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS3_k127_6912353_14	547045.NEISICOT_02160	4.461e-14	86.0	29355@1|root,2ZQN9@2|Bacteria,1RFN1@1224|Proteobacteria,2VSAG@28216|Betaproteobacteria,2KR84@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6912353_0	379066.GAU_1229	5.689e-209	660.0	COG1028@1|root,COG1028@2|Bacteria,1ZT0F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_6912353_6	357808.RoseRS_1915	8.211e-52	197.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_6912353_10	1380386.JIAW01000026_gene6900	6.442e-25	110.0	29XQK@1|root,30JGA@2|Bacteria,2IGVS@201174|Actinobacteria,2390P@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6912353_2	118173.KB235914_gene817	7.217e-80	274.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1HGKE@1150|Oscillatoriales	1117|Cyanobacteria	O	Ribosomal RNA adenine dimethylase	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS3_k127_6912353_12	1122951.ATUE01000005_gene2210	3.155e-17	89.0	COG3187@1|root,COG3187@2|Bacteria,1N78G@1224|Proteobacteria,1SGIJ@1236|Gammaproteobacteria,3NTI2@468|Moraxellaceae	1236|Gammaproteobacteria	O	META domain	hslJ	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
GDHHQS3_k127_6912353_5	861299.J421_4133	1.163e-56	203.0	2CB8S@1|root,30PE6@2|Bacteria,1ZV1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
GDHHQS3_k127_6912353_7	861299.J421_4134	7.569e-51	186.0	COG2197@1|root,COG2197@2|Bacteria,1ZV09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GDHHQS3_k127_6912353_4	1286106.MPL1_02313	6.427e-59	210.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
GDHHQS3_k127_6912353_9	452637.Oter_3057	3.76e-29	123.0	2DPXD@1|root,333T1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GDHHQS3_k127_6912353_1	639030.JHVA01000001_gene2668	3.052e-104	340.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_6912353_8	661478.OP10G_0348	1.715e-45	179.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_6912353_3	1429916.X566_21020	5.73e-63	225.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS3_k127_6912353_17	1206744.BAGL01000124_gene6578	1.777e-06	56.0	2DMBW@1|root,32I54@2|Bacteria,2IMJM@201174|Actinobacteria,4G1CC@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772,F420H2_quin_red
GDHHQS3_k127_6912353_16	926569.ANT_19770	3.469e-08	55.0	COG1073@1|root,COG1073@2|Bacteria,2G690@200795|Chloroflexi	200795|Chloroflexi	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
GDHHQS3_k127_6914736_1	886293.Sinac_3963	4.662e-126	414.0	COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_6914736_6	1242864.D187_007276	1.018e-05	56.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS3_k127_6914736_2	926549.KI421517_gene113	2.699e-112	376.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,47MHW@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6914736_0	861299.J421_0094	1.761e-199	629.0	COG0520@1|root,COG0520@2|Bacteria,1ZT1P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_6914736_5	1379270.AUXF01000004_gene3354	2.585e-31	126.0	COG0730@1|root,COG0730@2|Bacteria,1ZU67@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_6914736_4	743719.PaelaDRAFT_1340	3.902e-32	136.0	2BWG6@1|root,32WUM@2|Bacteria,1VBBF@1239|Firmicutes,4HNFJ@91061|Bacilli,26UFI@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6929538_11	861299.J421_2605	3.464e-58	216.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GDHHQS3_k127_6929538_10	861299.J421_2606	2.288e-65	231.0	COG2094@1|root,COG2094@2|Bacteria,1ZTNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS3_k127_6929538_1	861299.J421_2609	2.315e-193	610.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Beta-eliminating lyase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_6929538_3	861299.J421_2612	6.274e-178	563.0	COG1063@1|root,COG1063@2|Bacteria,1ZSWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_6929538_8	1254432.SCE1572_09415	5.302e-78	276.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_6929538_5	378806.STAUR_3780	1.024e-90	310.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria,2YV2D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
GDHHQS3_k127_6929538_18	1379270.AUXF01000004_gene3222	2.073e-05	48.0	2AF2N@1|root,31516@2|Bacteria,1ZV9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6929538_7	861299.J421_2615	7.373e-84	285.0	COG4123@1|root,COG4123@2|Bacteria,1ZTJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6929538_17	1254432.SCE1572_24640	1.611e-17	91.0	COG0745@1|root,COG1366@1|root,COG2202@1|root,COG0745@2|Bacteria,COG1366@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,439XN@68525|delta/epsilon subdivisions,2X1UZ@28221|Deltaproteobacteria,2Z0MJ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3,STAS
GDHHQS3_k127_6929538_16	399739.Pmen_1563	6.866e-20	98.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,1S7UX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	luxR family	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_6929538_12	1131553.JIBI01000023_gene323	3.044e-45	173.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K17071	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,AAA_25,CHAT,HTH_17,MEDS,NB-ARC,TPR_12
GDHHQS3_k127_6929538_9	861299.J421_2616	7.666e-71	248.0	COG0266@1|root,COG0266@2|Bacteria,1ZTMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_6929538_2	861299.J421_2617	3.973e-178	565.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_6929538_6	861299.J421_2619	3.601e-88	298.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG	-	-	ko:K02030,ko:K06950,ko:K07814,ko:K09749,ko:K16923	-	M00236,M00582	-	-	ko00000,ko00002,ko02000,ko02022	3.A.1.28,3.A.1.3	-	-	GAF_2,GGDEF,HD,HD_5,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_6929538_14	1158318.ATXC01000001_gene861	3.196e-30	127.0	COG0352@1|root,COG0352@2|Bacteria,2G43B@200783|Aquificae	200783|Aquificae	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_6929538_4	861299.J421_2620	2.961e-110	370.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS3_k127_6929538_13	379066.GAU_0666	2.051e-42	164.0	COG0816@1|root,COG0816@2|Bacteria,1ZTWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS3_k127_6929538_0	861299.J421_2622	4.354e-204	643.0	COG1158@1|root,COG1158@2|Bacteria,1ZSXH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_6933080_0	378806.STAUR_7575	0.0	1411.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2Z3GS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_6933080_3	867845.KI911784_gene2126	8.764e-50	182.0	COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi	200795|Chloroflexi	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
GDHHQS3_k127_6933080_2	861299.J421_0072	1.264e-96	330.0	COG0116@1|root,COG0116@2|Bacteria,1ZT80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	UPF0020
GDHHQS3_k127_6933080_1	861299.J421_0079	6.355e-216	678.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	2|Bacteria	L	RecQ zinc-binding	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,HRDC,Helicase_C,RecQ_Zn_bind
GDHHQS3_k127_6935028_2	404380.Gbem_1710	9.262e-50	182.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2WMH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS3_k127_6935028_0	379066.GAU_2366	3.409e-107	357.0	COG0573@1|root,COG0573@2|Bacteria,1ZUXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_6935028_1	379066.GAU_2367	1.543e-57	208.0	COG0581@1|root,COG0581@2|Bacteria,1ZV4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_6957671_1	379066.GAU_2138	3.158e-66	231.0	COG2859@1|root,COG2859@2|Bacteria,1ZUNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_6957671_0	861299.J421_4119	1.159e-218	692.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS3_k127_6957671_2	935840.JAEQ01000004_gene467	5.502e-31	124.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,43QU3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GDHHQS3_k127_6987602_1	861299.J421_3916	6.379e-99	329.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_6987602_0	861299.J421_3917	9.879e-221	695.0	COG0531@1|root,COG0531@2|Bacteria,1ZSUB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_6987602_2	379066.GAU_2451	4.477e-51	181.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GDHHQS3_k127_7025753_7	379066.GAU_0506	3.104e-67	230.0	COG1845@1|root,COG1845@2|Bacteria,1ZT8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS3_k127_7025753_13	379066.GAU_0507	1.964e-31	126.0	2EKS3@1|root,33EFV@2|Bacteria,1ZTY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GDHHQS3_k127_7025753_6	1379270.AUXF01000002_gene1829	1.757e-105	349.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GDHHQS3_k127_7025753_12	861299.J421_2404	3.949e-34	139.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7025753_2	379066.GAU_0513	9.676e-161	541.0	COG2027@1|root,COG2027@2|Bacteria,1ZT1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS3_k127_7025753_9	1419583.V466_11210	7.058e-58	209.0	COG2173@1|root,COG3786@1|root,COG2173@2|Bacteria,COG3786@2|Bacteria,1RENK@1224|Proteobacteria,1S3SJ@1236|Gammaproteobacteria,1YR3J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GDHHQS3_k127_7025753_11	1144275.COCOR_01613	2.071e-37	146.0	2CNQU@1|root,32SHJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
GDHHQS3_k127_7025753_10	909663.KI867150_gene1783	4.991e-46	177.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MQFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Lysin motif	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GDHHQS3_k127_7025753_1	861299.J421_2400	1.574e-171	546.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
GDHHQS3_k127_7025753_8	861299.J421_2399	7.436e-61	214.0	COG1832@1|root,COG1832@2|Bacteria,1ZTUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS3_k127_7025753_5	1379270.AUXF01000002_gene1820	1.396e-110	370.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_7025753_0	861299.J421_2396	0.0	1345.0	COG0188@1|root,COG0188@2|Bacteria,1ZTFF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_7025753_3	340099.Teth39_0432	1.684e-146	477.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,42FA0@68295|Thermoanaerobacterales	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
GDHHQS3_k127_7025753_4	1415778.JQMM01000001_gene1963	4.829e-118	398.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_7025753_14	1122603.ATVI01000005_gene3041	8.946e-22	108.0	COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
GDHHQS3_k127_7025753_15	1122603.ATVI01000005_gene3042	1.124e-20	94.0	COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales	135614|Xanthomonadales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
GDHHQS3_k127_7031332_1	861299.J421_1204	3.465e-161	518.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_7031332_2	1122605.KB893648_gene3540	9.472e-33	135.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
GDHHQS3_k127_7031332_0	1379270.AUXF01000004_gene3077	1.645e-202	642.0	COG0554@1|root,COG0554@2|Bacteria,1ZTX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_7032273_1	517418.Ctha_2365	2.09e-07	54.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	kaiB	GO:0003674,GO:0005488,GO:0005515,GO:0007623,GO:0008150,GO:0009605,GO:0009649,GO:0009892,GO:0010563,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0042325,GO:0042326,GO:0042752,GO:0042802,GO:0045936,GO:0048511,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051174,GO:0065007	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB,PAS_4
GDHHQS3_k127_7032273_0	861299.J421_0715	4.525e-159	518.0	COG0642@1|root,COG0642@2|Bacteria,1ZUEC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
GDHHQS3_k127_7045333_1	748247.AZKH_2215	1.235e-118	387.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VPRI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_7045333_0	748247.AZKH_2214	2.578e-133	438.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1R8JK@1224|Proteobacteria,2WEZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_7059293_0	861299.J421_1403	0.0	1618.0	COG1201@1|root,COG1201@2|Bacteria,1ZTN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS3_k127_7059293_1	861299.J421_0459	1.333e-154	499.0	COG1502@1|root,COG1502@2|Bacteria,1ZTU6@142182|Gemmatimonadetes	2|Bacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GDHHQS3_k127_7059293_2	379066.GAU_0172	3.426e-122	397.0	COG5534@1|root,COG5534@2|Bacteria,1ZTEX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RPA
GDHHQS3_k127_7059523_7	1379270.AUXF01000002_gene1705	2.882e-22	99.0	28NRS@1|root,2ZBQZ@2|Bacteria,1ZV13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7059523_0	861299.J421_2603	2.555e-79	269.0	COG0432@1|root,COG0432@2|Bacteria,1ZV8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_7059523_8	204669.Acid345_3258	3.357e-18	87.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS3_k127_7059523_3	1449049.JONW01000011_gene2311	6.97e-37	148.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7059523_6	861299.J421_5835	3.688e-24	109.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_7059523_5	278963.ATWD01000001_gene1694	6.045e-29	121.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria,2JJNM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7059523_1	1379270.AUXF01000002_gene1709	2.367e-55	197.0	COG2166@1|root,COG2166@2|Bacteria,1ZTPH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
GDHHQS3_k127_7059523_4	498848.TaqDRAFT_3718	9.626e-37	143.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_7059523_2	1123368.AUIS01000030_gene1247	7.222e-44	166.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
GDHHQS3_k127_7059523_9	861299.J421_0079	5.159e-18	84.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	2|Bacteria	L	RecQ zinc-binding	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,HRDC,Helicase_C,RecQ_Zn_bind
GDHHQS3_k127_7060452_4	861299.J421_2662	3.966e-54	191.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_7060452_3	485918.Cpin_7085	1.345e-97	335.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_7060452_0	379066.GAU_0749	8.391e-175	557.0	COG0022@1|root,COG0022@2|Bacteria,1ZTA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS3_k127_7060452_2	861299.J421_2668	2.726e-145	472.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS3_k127_7060452_1	1379270.AUXF01000004_gene3127	3.454e-167	527.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS3_k127_7070416_0	861299.J421_3751	0.0	1028.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
GDHHQS3_k127_7070416_3	861299.J421_3752	9.243e-113	373.0	COG0859@1|root,COG0859@2|Bacteria,1ZSYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS3_k127_7070416_1	861299.J421_3753	3.013e-148	478.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_7070416_2	1379270.AUXF01000003_gene3691	3.234e-134	434.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7070416_4	861299.J421_3755	3.825e-62	220.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7072051_2	861299.J421_3635	1.841e-87	296.0	COG0565@1|root,COG0565@2|Bacteria,1ZT19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	SpoU rRNA Methylase family	-	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS3_k127_7072051_3	861299.J421_3631	1.731e-74	254.0	COG2010@1|root,COG2010@2|Bacteria,1ZTKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS3_k127_7072051_0	861299.J421_3630	0.0	1311.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GDHHQS3_k127_7072051_1	861299.J421_3629	6.729e-110	361.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS3_k127_7077171_1	861299.J421_1395	1.315e-83	295.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_7077171_0	518766.Rmar_1990	3.95e-125	411.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
GDHHQS3_k127_7077171_3	1454007.JAUG01000020_gene1644	3.19e-27	117.0	COG2318@1|root,COG2318@2|Bacteria,4NX8X@976|Bacteroidetes,1IU1A@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_7077171_2	401053.AciPR4_1659	2.858e-32	131.0	COG1846@1|root,COG1846@2|Bacteria,3Y97P@57723|Acidobacteria,2JNFY@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS3_k127_7077171_4	523791.Kkor_1230	7.122e-21	96.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria,1S7BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_7102898_1	861299.J421_4121	6.737e-182	576.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS3_k127_7102898_0	1254432.SCE1572_38000	9.584e-215	672.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7102898_2	349521.HCH_05597	4.355e-30	124.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,1XKS3@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_7102898_3	1042209.HK44_012675	3.437e-27	111.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1YTPA@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_7103461_10	861299.J421_3825	4.269e-29	122.0	COG0806@1|root,COG0806@2|Bacteria,1ZU43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_7103461_2	379066.GAU_2332	7.827e-107	349.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS3_k127_7103461_14	443152.MDG893_03545	5.504e-06	54.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,46BZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7103461_13	377629.TERTU_0630	4.771e-06	55.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,2PPQT@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7103461_6	861299.J421_3822	6.417e-59	207.0	COG0335@1|root,COG0335@2|Bacteria,1ZTUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS3_k127_7103461_3	1379270.AUXF01000003_gene3642	3.157e-77	269.0	COG0164@1|root,COG0164@2|Bacteria,1ZTHY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS3_k127_7103461_4	869210.Marky_1689	1.37e-68	238.0	COG0041@1|root,COG0041@2|Bacteria,1WJ89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS3_k127_7103461_1	526227.Mesil_1291	2.336e-125	418.0	COG0026@1|root,COG0026@2|Bacteria,1WITC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
GDHHQS3_k127_7103461_5	861299.J421_4375	1.087e-61	221.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7103461_9	861299.J421_4376	7.399e-43	168.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7103461_7	861299.J421_4377	1.905e-58	216.0	COG3595@1|root,COG3595@2|Bacteria,1ZU53@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_7103461_12	1394178.AWOO02000027_gene5300	3.104e-08	64.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,4EHWS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_7103461_8	667632.KB890220_gene2859	4.867e-45	170.0	COG1845@1|root,COG1845@2|Bacteria,1RG95@1224|Proteobacteria,2VS0Y@28216|Betaproteobacteria,1K694@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
GDHHQS3_k127_7103461_0	379066.GAU_2548	4.541e-161	533.0	COG4772@1|root,COG4772@2|Bacteria,1ZT8H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_7103461_11	204669.Acid345_3014	2.151e-11	64.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_7124541_0	861299.J421_3046	2.371e-128	428.0	COG0659@1|root,COG2976@1|root,COG0659@2|Bacteria,COG2976@2|Bacteria	2|Bacteria	CO	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21,TPR_6,TPR_8
GDHHQS3_k127_7144434_3	1379270.AUXF01000004_gene3072	5.199e-09	68.0	COG1864@1|root,COG2374@1|root,COG3291@1|root,COG5492@1|root,COG1864@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1ZUE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	DNA/RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Endonuclease_NS,PKD
GDHHQS3_k127_7144434_0	1379270.AUXF01000004_gene2872	7.37e-74	266.0	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria,1ZUHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DKLTZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RCC1
GDHHQS3_k127_7144434_1	671143.DAMO_0171	3.135e-38	148.0	2C82G@1|root,32RK9@2|Bacteria,2NRTP@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GDHHQS3_k127_7144434_2	331678.Cphamn1_0275	3.03e-23	107.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_7144434_5	1169152.AXVD01000007_gene1893	1.161e-07	53.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,Chlorophyllase2,DLH
GDHHQS3_k127_7146389_1	861299.J421_1725	5.298e-115	383.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1725|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7146389_0	196367.JNFG01000008_gene6532	2.256e-191	613.0	COG3829@1|root,COG3852@1|root,COG4191@1|root,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KGEM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS3_k127_7146389_3	1267535.KB906767_gene1910	9.006e-50	181.0	COG4566@1|root,COG4566@2|Bacteria,3Y58V@57723|Acidobacteria,2JJQJ@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_7146389_2	196367.JNFG01000008_gene6541	6.815e-85	286.0	COG4566@1|root,COG4566@2|Bacteria,1RAWG@1224|Proteobacteria,2WEM4@28216|Betaproteobacteria,1K7J4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7146389_4	525904.Tter_0477	9.504e-05	53.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7155513_0	234267.Acid_4499	4.463e-95	321.0	COG0451@1|root,COG0451@2|Bacteria,3Y91Q@57723|Acidobacteria	57723|Acidobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7155513_1	379066.GAU_2691	1.692e-83	293.0	2CCCP@1|root,33QJX@2|Bacteria,1ZTIZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7155513_2	1234364.AMSF01000025_gene3696	1.103e-40	156.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XCEX@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_7155964_4	861299.J421_3334	1.121e-173	554.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	861299.J421_3334|-	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7155964_1	861299.J421_3333	3.323e-225	713.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_7155964_14	379066.GAU_1696	5.083e-52	192.0	COG0584@1|root,COG0584@2|Bacteria,1ZTTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS3_k127_7155964_13	861299.J421_3331	5.67e-61	215.0	COG1595@1|root,COG1595@2|Bacteria,1ZTKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7155964_17	861299.J421_3330	4.064e-08	62.0	2AETF@1|root,314QF@2|Bacteria,1ZU7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_7155964_16	861299.J421_3329	1.336e-21	100.0	297VI@1|root,2ZV24@2|Bacteria,1ZU61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7155964_0	379066.GAU_0522	0.0	1129.0	COG0841@1|root,COG0841@2|Bacteria,1ZT98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS3_k127_7155964_10	1379270.AUXF01000002_gene1841	4.512e-83	289.0	COG0845@1|root,COG0845@2|Bacteria,1ZTJD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS3_k127_7155964_8	861299.J421_6127	6.164e-93	324.0	COG1309@1|root,COG1538@1|root,COG1309@2|Bacteria,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	ttgC	-	-	-	-	-	-	-	-	-	-	-	OEP,TetR_N
GDHHQS3_k127_7155964_2	861299.J421_3325	2.442e-193	617.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
GDHHQS3_k127_7155964_3	1379270.AUXF01000006_gene199	1.502e-177	568.0	COG0260@1|root,COG0260@2|Bacteria,1ZSPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS3_k127_7155964_7	861299.J421_3323	1.921e-102	361.0	COG4206@1|root,COG4206@2|Bacteria,1ZT1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
GDHHQS3_k127_7155964_9	861299.J421_3322	7.007e-92	310.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GDHHQS3_k127_7155964_11	379066.GAU_1689	1.164e-73	256.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS3_k127_7155964_15	1379270.AUXF01000006_gene203	1.827e-25	106.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
GDHHQS3_k127_7155964_5	861299.J421_3319	5.836e-154	502.0	COG0452@1|root,COG0452@2|Bacteria,1ZV19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS3_k127_7155964_12	56780.SYN_02178	5.86e-62	224.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MQDY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_7155964_6	379066.GAU_1686	6.752e-139	449.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS3_k127_7176382_1	861299.J421_4541	3.533e-23	105.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_7176382_4	84531.JMTZ01000068_gene1720	4.832e-05	57.0	COG1409@1|root,COG1409@2|Bacteria,1N44U@1224|Proteobacteria,1RY17@1236|Gammaproteobacteria,1X3WN@135614|Xanthomonadales	135614|Xanthomonadales	S	calcineurin phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
GDHHQS3_k127_7176382_0	1379270.AUXF01000005_gene793	1.348e-40	161.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
GDHHQS3_k127_7178382_6	861299.J421_3236	3.046e-30	121.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS3_k127_7178382_1	861299.J421_3235	4.154e-208	654.0	COG1160@1|root,COG1160@2|Bacteria,1ZSQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS3_k127_7178382_2	861299.J421_3234	8.481e-202	635.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
GDHHQS3_k127_7178382_0	861299.J421_3231	1.77e-292	909.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
GDHHQS3_k127_7178382_3	861299.J421_3230	3.967e-170	556.0	COG0728@1|root,COG0728@2|Bacteria,1ZTCM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_7178382_4	861299.J421_3229	8.422e-141	464.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
GDHHQS3_k127_7178382_5	1341151.ASZU01000010_gene1884	7.601e-37	145.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_7185145_2	379066.GAU_1924	1.617e-44	163.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_7185145_0	861299.J421_3533	1.961e-248	771.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS3_k127_7185145_1	861299.J421_3532	1.01e-81	278.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
GDHHQS3_k127_7289733_1	379066.GAU_0440	3.319e-123	404.0	COG1960@1|root,COG1960@2|Bacteria,1ZUHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_7289733_0	861299.J421_1510	1.813e-207	658.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS3_k127_7326956_11	379066.GAU_1414	9.938e-51	185.0	COG2201@1|root,COG2201@2|Bacteria,1ZUFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GDHHQS3_k127_7326956_5	1248916.ANFY01000005_gene2779	2.067e-156	501.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2K275@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_7326956_12	861299.J421_3066	2.422e-10	65.0	2DENK@1|root,2ZNKE@2|Bacteria,1ZV91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7326956_8	861299.J421_3067	1.614e-104	361.0	COG0457@1|root,COG0457@2|Bacteria,1ZSXZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7326956_9	379066.GAU_1420	1.988e-103	344.0	COG0275@1|root,COG0275@2|Bacteria,1ZT4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS3_k127_7326956_0	861299.J421_3070	4.771e-186	606.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_7326956_1	861299.J421_3071	4.932e-182	581.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_7326956_2	861299.J421_3072	1.168e-173	556.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_7326956_3	1379270.AUXF01000005_gene687	3.021e-166	531.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
GDHHQS3_k127_7326956_4	861299.J421_3074	2.76e-159	515.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_7326956_6	861299.J421_3075	6.361e-143	463.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_7326956_7	861299.J421_3076	2.372e-130	426.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS3_k127_7326956_10	861299.J421_3077	3.622e-53	192.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_7328613_1	861299.J421_2662	2.89e-192	606.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_7328613_3	861299.J421_2661	2.489e-84	285.0	COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_7328613_0	861299.J421_2660	1.223e-299	933.0	COG0210@1|root,COG0210@2|Bacteria,1ZSMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS3_k127_7328613_2	861299.J421_2658	1.018e-117	389.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
GDHHQS3_k127_7352170_5	1380390.JIAT01000009_gene330	9.19e-18	92.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GDHHQS3_k127_7352170_3	706587.Desti_1483	1.623e-62	226.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
GDHHQS3_k127_7352170_4	1267533.KB906734_gene4268	2.394e-33	140.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria,2JJ3U@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS3_k127_7352170_0	1340493.JNIF01000004_gene335	7.247e-191	607.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria	57723|Acidobacteria	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_7352170_1	883126.HMPREF9710_00067	1.298e-142	477.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS3_k127_7352170_2	1131462.DCF50_p374	1.304e-109	367.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,26141@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_7360275_4	32057.KB217478_gene7011	1.769e-97	326.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1HR77@1161|Nostocales	1117|Cyanobacteria	EU	Prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_7360275_1	861299.J421_4435	6.566e-168	533.0	COG0205@1|root,COG0205@2|Bacteria,1ZTAR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_7360275_7	997346.HMPREF9374_0031	9.129e-08	55.0	COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,4HR9S@91061|Bacilli	91061|Bacilli	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS3_k127_7360275_2	1379698.RBG1_1C00001G0798	1.212e-108	380.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
GDHHQS3_k127_7360275_6	861299.J421_4437	5.602e-20	94.0	COG4970@1|root,COG4970@2|Bacteria,1ZU5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Tfp pilus assembly protein FimT	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7360275_0	1379270.AUXF01000001_gene2562	1.672e-181	577.0	COG0513@1|root,COG0513@2|Bacteria,1ZSX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS3_k127_7360275_5	861299.J421_4443	2.441e-60	219.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GDHHQS3_k127_7360275_3	1379270.AUXF01000001_gene2561	1.863e-104	352.0	2EW3S@1|root,33PH0@2|Bacteria,1ZTQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7371072_1	861299.J421_3844	1.292e-171	548.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS3_k127_7371072_4	861299.J421_2745	4.874e-39	148.0	COG1324@1|root,COG1324@2|Bacteria,1ZV6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS3_k127_7371072_3	379066.GAU_0826	1.541e-117	383.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_7371072_2	1379270.AUXF01000004_gene3069	9.55e-165	536.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
GDHHQS3_k127_7371072_5	861299.J421_3217	1.62e-35	143.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GDHHQS3_k127_7371072_0	1128421.JAGA01000003_gene3258	2.269e-183	595.0	COG2303@1|root,COG2303@2|Bacteria,2NRUE@2323|unclassified Bacteria	2|Bacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
GDHHQS3_k127_7391612_5	861299.J421_2712	9.927e-32	125.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GDHHQS3_k127_7391612_6	1379270.AUXF01000004_gene3089	3.398e-27	120.0	COG1719@1|root,COG1719@2|Bacteria,1ZU65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7391612_0	861299.J421_2714	1.281e-266	839.0	COG0272@1|root,COG0272@2|Bacteria,1ZT5Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS3_k127_7391612_2	861299.J421_2715	5.532e-123	404.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_7391612_4	861299.J421_2716	2.93e-71	242.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7391612_3	861299.J421_2718	6.211e-72	251.0	COG0457@1|root,COG0457@2|Bacteria,1ZTR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7391612_1	1379270.AUXF01000004_gene3085	1.86e-175	559.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS3_k127_7391612_7	379066.GAU_1126	5.889e-27	111.0	COG2315@1|root,COG2315@2|Bacteria,1ZV10@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS3_k127_7418816_0	1340493.JNIF01000004_gene652	3.843e-137	442.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_7418816_2	933262.AXAM01000028_gene3328	8.929e-13	75.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,43CGA@68525|delta/epsilon subdivisions,2X7RB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_7418816_1	1229205.BUPH_02961	2.07e-69	241.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,2VK6N@28216|Betaproteobacteria,1K2FW@119060|Burkholderiaceae	28216|Betaproteobacteria	C	dihydroorotate dehydrogenase family	yeiA	-	1.3.1.1,1.3.1.14	ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21,Fer4_6
GDHHQS3_k127_7419565_6	1443665.JACA01000049_gene5417	4.419e-19	91.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1I3KX@117743|Flavobacteriia,2YJ63@290174|Aquimarina	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
GDHHQS3_k127_7419565_5	861299.J421_6117	1.531e-26	115.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS3_k127_7419565_0	404589.Anae109_0941	5.841e-103	347.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,2YVBA@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
GDHHQS3_k127_7419565_7	1123278.KB893574_gene6167	1.045e-09	67.0	2DP97@1|root,3313P@2|Bacteria,4PP9H@976|Bacteroidetes,47SB2@768503|Cytophagia	976|Bacteroidetes	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GDHHQS3_k127_7419565_1	290397.Adeh_0511	4.721e-96	334.0	COG0475@1|root,COG0475@2|Bacteria,1RA3J@1224|Proteobacteria,43EWJ@68525|delta/epsilon subdivisions,2WTW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_7419565_2	861299.J421_5698	5.065e-76	260.0	COG2197@1|root,COG2197@2|Bacteria,1ZUCS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7419565_3	1173027.Mic7113_4769	5.304e-44	176.0	COG2203@1|root,COG4191@1|root,COG5000@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1G4JT@1117|Cyanobacteria,1H87T@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GDHHQS3_k127_7419565_4	1232410.KI421426_gene1400	3.194e-40	150.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,42PW8@68525|delta/epsilon subdivisions,2WKCT@28221|Deltaproteobacteria,43UTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
GDHHQS3_k127_7513355_0	402612.FP0003	3.945e-169	549.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia,2NTS5@237|Flavobacterium	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS3_k127_7513355_1	861299.J421_4347	2.029e-55	205.0	COG0697@1|root,COG0697@2|Bacteria,1ZTRH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_7513355_2	1117108.PAALTS15_06058	1.148e-19	95.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,26SC4@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF541)	bp26	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_7519008_0	1379270.AUXF01000004_gene3094	3.4e-262	820.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_7519008_4	379066.GAU_0785	3.182e-19	99.0	2AEY4@1|root,314VZ@2|Bacteria,1ZUUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7519008_1	861299.J421_2710	2.007e-123	399.0	COG0455@1|root,COG0455@2|Bacteria,1ZTAN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_7519008_2	861299.J421_2711	1.32e-56	201.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
GDHHQS3_k127_7519008_3	861299.J421_2712	5.006e-50	181.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GDHHQS3_k127_762226_3	861299.J421_2251	5.508e-40	156.0	COG3525@1|root,COG3525@2|Bacteria,1ZUG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
GDHHQS3_k127_762226_0	861299.J421_2685	0.0	1420.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GDHHQS3_k127_762226_2	861299.J421_2684	8.869e-66	233.0	COG0095@1|root,COG0095@2|Bacteria,1ZTY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_762226_1	861299.J421_2683	1.623e-76	268.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_7631261_1	65093.PCC7418_1870	2.965e-74	259.0	COG0500@1|root,COG2226@2|Bacteria,1GQEQ@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_7631261_3	1121127.JAFA01000007_gene5155	1.633e-22	107.0	COG1670@1|root,COG1670@2|Bacteria,1P3KU@1224|Proteobacteria,2W4YV@28216|Betaproteobacteria,1K3YK@119060|Burkholderiaceae	28216|Betaproteobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_7631261_2	330214.NIDE2686	7.486e-55	199.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS3_k127_7631261_0	1349767.GJA_2643	2.861e-135	452.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,473C1@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	- Amino acid transport and metabolism	asnB1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_7631261_4	370438.PTH_0387	5.173e-13	80.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,2673T@186807|Peptococcaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_766345_1	379066.GAU_3906	4.98e-71	257.0	COG3055@1|root,COG3055@2|Bacteria,1ZUV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
GDHHQS3_k127_766345_0	760192.Halhy_1130	0.0	1272.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1IRCI@117747|Sphingobacteriia	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
GDHHQS3_k127_766345_2	1234364.AMSF01000025_gene3734	2.897e-06	55.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1X3S1@135614|Xanthomonadales	135614|Xanthomonadales	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_7743231_1	861299.J421_2042	1.568e-36	149.0	COG0308@1|root,COG0308@2|Bacteria,1ZU50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS3_k127_7743231_0	234267.Acid_0469	0.0	1006.0	COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS3_k127_7743231_2	861299.J421_0690	4.56e-35	138.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_7775697_3	1122604.JONR01000025_gene4602	4.581e-129	436.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
GDHHQS3_k127_7775697_9	1415780.JPOG01000001_gene1457	1.669e-41	158.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,1RMFE@1236|Gammaproteobacteria,1X43J@135614|Xanthomonadales	135614|Xanthomonadales	I	Alpha beta hydrolase	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
GDHHQS3_k127_7775697_14	1385935.N836_32250	3.569e-12	74.0	2A53S@1|root,30TSD@2|Bacteria,1GGW0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7775697_4	1403819.BATR01000162_gene5394	2.034e-119	393.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_7775697_1	1403819.BATR01000162_gene5393	5.781e-164	535.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,46WZH@74201|Verrucomicrobia,2IVZE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7775697_11	1301098.PKB_3595	3.703e-34	145.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	yidR	GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
GDHHQS3_k127_7775697_12	1038860.AXAP01000003_gene8375	1.513e-14	84.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
GDHHQS3_k127_7775697_16	519989.ECTPHS_10986	3.338e-06	58.0	COG1716@1|root,COG1716@2|Bacteria,1N5QD@1224|Proteobacteria,1SAA3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG1716 FOG FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_7775697_0	1267533.KB906736_gene1246	1.128e-197	648.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_7775697_17	497964.CfE428DRAFT_1853	2.278e-05	48.0	COG1061@1|root,COG4916@1|root,COG1061@2|Bacteria,COG4916@2|Bacteria,46VMH@74201|Verrucomicrobia	74201|Verrucomicrobia	KL	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
GDHHQS3_k127_7775697_2	1396141.BATP01000019_gene1735	2.807e-129	450.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,46XFS@74201|Verrucomicrobia,2IVSV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_7775697_6	497964.CfE428DRAFT_4864	6.79e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7775697_7	485913.Krac_1339	1.942e-53	198.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_7775697_10	526225.Gobs_1610	1.457e-35	141.0	COG3631@1|root,COG3631@2|Bacteria,2GQBR@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS3_k127_7775697_5	1117943.SFHH103_02774	1.338e-58	217.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_7775697_15	1254432.SCE1572_31350	5.303e-09	58.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180,PadR
GDHHQS3_k127_7775697_8	404589.Anae109_3495	5.302e-45	170.0	2CK59@1|root,32VV2@2|Bacteria,1P616@1224|Proteobacteria,4329Y@68525|delta/epsilon subdivisions,2X772@28221|Deltaproteobacteria,2YVDY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7788634_4	379066.GAU_3248	8.053e-32	141.0	COG3419@1|root,COG3419@2|Bacteria,1ZUGY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_7788634_3	1118054.CAGW01000046_gene1548	1.171e-83	289.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26QN5@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_7788634_2	861299.J421_3591	3.663e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_7788634_1	861299.J421_3592	3.518e-97	325.0	COG0613@1|root,COG0613@2|Bacteria,1ZTHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GDHHQS3_k127_7788634_5	1379270.AUXF01000003_gene3865	6.894e-27	117.0	2FHQX@1|root,349IG@2|Bacteria,1ZU2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7788634_6	379066.GAU_1992	4.857e-08	57.0	2AF2V@1|root,3151C@2|Bacteria,1ZVA0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7788634_0	861299.J421_3595	9.344e-135	438.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_7863820_2	1191523.MROS_1983	1.33e-37	143.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_7863820_6	402881.Plav_3270	2.175e-09	61.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,1JP0J@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_7863820_1	1123288.SOV_1c12410	1.902e-51	188.0	COG0693@1|root,COG0693@2|Bacteria,1TPJK@1239|Firmicutes,4H940@909932|Negativicutes	909932|Negativicutes	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
GDHHQS3_k127_7863820_8	1217710.F969_01067	1.33e-05	54.0	COG1983@1|root,COG1983@2|Bacteria,1NAUA@1224|Proteobacteria,1SD7E@1236|Gammaproteobacteria,3NPCM@468|Moraxellaceae	1236|Gammaproteobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
GDHHQS3_k127_7863820_3	1173022.Cri9333_0161	7.616e-35	141.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HCE9@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GDHHQS3_k127_7863820_0	661478.OP10G_2740	1.26e-62	224.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
GDHHQS3_k127_7863820_4	375286.mma_2596	1.483e-29	119.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS3_k127_7867927_2	379066.GAU_1174	3.779e-98	325.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS3_k127_7867927_4	861299.J421_2925	6.744e-69	239.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS3_k127_7867927_5	523791.Kkor_0414	1.777e-34	151.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XHEB@135619|Oceanospirillales	135619|Oceanospirillales	O	Peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GDHHQS3_k127_7867927_6	998088.B565_2194	1.358e-15	85.0	COG0454@1|root,COG0456@2|Bacteria,1NCV9@1224|Proteobacteria,1SDNT@1236|Gammaproteobacteria,1Y6BE@135624|Aeromonadales	135624|Aeromonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_7867927_1	861299.J421_2922	5.86e-144	460.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_7867927_3	861299.J421_2921	6.862e-81	276.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS3_k127_7867927_0	861299.J421_2920	8.072e-213	664.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS3_k127_7870638_23	552398.HMPREF0866_01038	8.741e-06	49.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS3_k127_7870638_14	1267533.KB906733_gene2915	5.588e-39	148.0	COG0346@1|root,COG0346@2|Bacteria,3Y7XQ@57723|Acidobacteria,2JMYD@204432|Acidobacteriia	204432|Acidobacteriia	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7870638_18	861299.J421_0551	4.7e-30	126.0	2DNQD@1|root,32YJR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
GDHHQS3_k127_7870638_8	365046.Rta_15000	1.294e-79	274.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GDHHQS3_k127_7870638_17	861299.J421_0429	2.925e-30	128.0	294MB@1|root,2ZS0S@2|Bacteria,1ZU7M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7870638_5	861299.J421_2864	6.94e-128	421.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
GDHHQS3_k127_7870638_4	861299.J421_2587	3.01e-128	415.0	COG1173@1|root,COG1173@2|Bacteria,1ZT0U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_7870638_6	861299.J421_2586	1.972e-127	413.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_7870638_19	1033734.CAET01000016_gene4084	6.77e-14	83.0	COG4641@1|root,COG4641@2|Bacteria,1TRY6@1239|Firmicutes,4HJAS@91061|Bacilli,1ZARJ@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,LysM
GDHHQS3_k127_7870638_11	323097.Nham_3038	1.488e-62	218.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,2U5TI@28211|Alphaproteobacteria,3K6DR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GDHHQS3_k127_7870638_3	306281.AJLK01000062_gene4979	1.052e-135	439.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria,1JK84@1189|Stigonemataceae	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_7870638_2	211165.AJLN01000116_gene3438	1.894e-145	471.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_7870638_16	861299.J421_0320	8.915e-32	130.0	2DKY3@1|root,32UFX@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_7870638_13	335543.Sfum_0374	2.844e-52	194.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MRJB@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7870638_12	861299.J421_2584	2.582e-61	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GDHHQS3_k127_7870638_1	861299.J421_2583	4.048e-211	682.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_7870638_0	861299.J421_2582	2.082e-277	866.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
GDHHQS3_k127_7870638_22	379066.GAU_0637	7.104e-07	57.0	29FAB@1|root,3027Z@2|Bacteria,1ZUYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7870638_7	861299.J421_2581	3.62e-98	327.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GDHHQS3_k127_7870638_10	861299.J421_2580	6.654e-65	228.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS3_k127_7870638_9	861299.J421_2579	3.372e-74	254.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS3_k127_7870638_15	1341155.FSS13T_07980	3.75e-34	136.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia,2NX9M@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GDHHQS3_k127_7870638_20	1968.JOEV01000002_gene7255	3.205e-09	60.0	COG1309@1|root,COG1309@2|Bacteria,2IEEE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_7876280_1	861299.J421_5794	6.193e-106	373.0	COG0515@1|root,COG0515@2|Bacteria,1ZUMJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_7876280_3	502025.Hoch_1576	7.492e-49	183.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS3_k127_7876280_8	1129794.C427_4351	6.343e-19	87.0	2DQG8@1|root,336NX@2|Bacteria,1P0JX@1224|Proteobacteria,1SRGM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7876280_4	379066.GAU_0898	3.962e-47	175.0	COG2318@1|root,COG2318@2|Bacteria,1ZU3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_7876280_5	379066.GAU_3293	1.019e-32	140.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
GDHHQS3_k127_7876280_0	204669.Acid345_1052	1.927e-115	400.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_7876280_2	861299.J421_1634	1.09e-103	347.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GDHHQS3_k127_7876280_7	1121405.dsmv_1231	1.2e-19	89.0	COG0834@1|root,COG2202@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4,SBP_bac_3,dCache_1
GDHHQS3_k127_7883900_6	1121468.AUBR01000001_gene406	3.394e-09	63.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Big_2,Flg_new,Metallophos,Pur_ac_phosph_N,SLH
GDHHQS3_k127_7883900_2	1379270.AUXF01000003_gene3470	7.292e-65	236.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GDHHQS3_k127_7883900_0	861299.J421_1048	1.873e-302	953.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_7883900_1	379066.GAU_0170	1.791e-145	470.0	COG0823@1|root,COG0823@2|Bacteria,1ZTFG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_7883900_3	861299.J421_0700	4.987e-58	207.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55,5.5.1.4	ko:K01858,ko:K03207,ko:K03574	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
GDHHQS3_k127_7883900_4	861299.J421_1140	1.362e-49	183.0	28JRZ@1|root,2Z9HI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GDHHQS3_k127_7894519_0	861299.J421_4157	2.977e-170	540.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_7894519_1	379066.GAU_2570	2.662e-124	402.0	COG2804@1|root,COG2804@2|Bacteria,1ZSSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_7897280_0	768671.ThimaDRAFT_4782	1.084e-95	329.0	COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,1S8TI@1236|Gammaproteobacteria,1WZBX@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS3_k127_7897280_1	1123400.KB904778_gene1684	9.266e-72	276.0	2C2I8@1|root,2ZFX0@2|Bacteria,1P44T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7899039_5	509190.Cseg_0880	7.539e-19	88.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
GDHHQS3_k127_7899039_4	861299.J421_4494	2.18e-27	115.0	COG3682@1|root,COG3682@2|Bacteria,1ZU4Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS3_k127_7899039_3	420324.KI911999_gene8063	3.246e-59	217.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7899039_1	670292.JH26_11815	1.68e-121	400.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7899039_2	335543.Sfum_1623	7.252e-82	295.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GDHHQS3_k127_7899039_0	861299.J421_2314	9.172e-144	466.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_7899039_6	861299.J421_2315	8.615e-19	86.0	COG1079@1|root,COG1079@2|Bacteria,1ZTFZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_7916042_0	1121430.JMLG01000005_gene718	2.39e-124	413.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS3_k127_7916042_2	861299.J421_2991	7.454e-46	173.0	COG0241@1|root,COG0241@2|Bacteria,1ZTT8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GDHHQS3_k127_7916042_1	861299.J421_2990	1.584e-58	209.0	COG0299@1|root,COG0299@2|Bacteria,1ZTKJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS3_k127_7917644_3	502558.EGYY_09920	6.951e-07	63.0	COG4625@1|root,COG4625@2|Bacteria,2GWTB@201174|Actinobacteria	201174|Actinobacteria	S	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
GDHHQS3_k127_7917644_0	330214.NIDE3060	6.137e-96	321.0	COG2022@1|root,COG2022@2|Bacteria,3J0EI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS3_k127_7917644_2	1279038.KB907344_gene3604	1.449e-10	66.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2UG5I@28211|Alphaproteobacteria,2JY1B@204441|Rhodospirillales	204441|Rhodospirillales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
GDHHQS3_k127_7917644_1	479434.Sthe_1493	6.827e-21	95.0	COG0352@1|root,COG0352@2|Bacteria,2G9BW@200795|Chloroflexi,27YDG@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_7946559_0	1242864.D187_005776	2.485e-175	555.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7946559_1	1163409.UUA_06454	5.123e-57	201.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1X6M5@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_7946559_2	1535287.JP74_07995	8.862e-31	123.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,3N90Q@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
GDHHQS3_k127_7946559_3	925409.KI911562_gene2549	2.257e-11	68.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
GDHHQS3_k127_7948714_5	468059.AUHA01000002_gene532	7.598e-52	184.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,1IP72@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
GDHHQS3_k127_7948714_3	468059.AUHA01000002_gene531	6.418e-70	248.0	29Z06@1|root,30KX7@2|Bacteria,4NZNI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS3_k127_7948714_8	1121931.AUHG01000010_gene318	2.87e-47	177.0	COG3023@1|root,COG3876@1|root,COG3023@2|Bacteria,COG3876@2|Bacteria,4NIY6@976|Bacteroidetes,1I0U3@117743|Flavobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DUF1343
GDHHQS3_k127_7948714_2	1183438.GKIL_3207	2.41e-78	280.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
GDHHQS3_k127_7948714_7	883126.HMPREF9710_00703	1.477e-47	178.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2VTYH@28216|Betaproteobacteria,4774B@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
GDHHQS3_k127_7948714_6	861299.J421_3035	1.716e-51	190.0	COG0526@1|root,COG0526@2|Bacteria,1ZU4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
GDHHQS3_k127_7948714_4	861299.J421_1044	1.458e-60	222.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1044|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7948714_9	323848.Nmul_A1488	2.271e-13	77.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,2VY5U@28216|Betaproteobacteria,373KS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
GDHHQS3_k127_7948714_0	861299.J421_1125	8.428e-156	500.0	COG0208@1|root,COG0208@2|Bacteria,1ZTAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
GDHHQS3_k127_7948714_1	861299.J421_2433	3.213e-89	297.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_7975805_15	861299.J421_1163	3.812e-37	141.0	COG0445@1|root,COG0445@2|Bacteria,1ZT9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GDHHQS3_k127_7975805_17	379066.GAU_0031	5.25e-31	124.0	2FICF@1|root,34A4P@2|Bacteria,1ZTX7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7975805_16	861299.J421_1159	2.866e-32	132.0	COG1585@1|root,COG1585@2|Bacteria,1ZTYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7975805_10	1283284.AZUK01000001_gene284	3.445e-74	261.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1Y61V@135624|Aeromonadales	135624|Aeromonadales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_7975805_7	861299.J421_1183	2.292e-122	405.0	COG0429@1|root,COG0429@2|Bacteria,1ZSTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
GDHHQS3_k127_7975805_14	861299.J421_1222	2.506e-44	164.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
GDHHQS3_k127_7975805_0	1379270.AUXF01000002_gene1467	3.382e-219	695.0	COG0111@1|root,COG0111@2|Bacteria,1ZSVM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_7975805_3	379066.GAU_0194	1.15e-160	518.0	COG0277@1|root,COG0277@2|Bacteria,1ZT16@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_7975805_13	861299.J421_1679	4.163e-56	207.0	COG0560@1|root,COG0560@2|Bacteria,1ZTS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
GDHHQS3_k127_7975805_6	379066.GAU_0192	1.39e-122	406.0	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_7975805_1	1379270.AUXF01000002_gene1243	2.633e-206	662.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_7975805_5	379066.GAU_0128	7.751e-130	421.0	COG0812@1|root,COG0812@2|Bacteria,1ZSMJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS3_k127_7975805_2	861299.J421_1260	3.782e-183	584.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_7975805_4	1379270.AUXF01000002_gene1395	7.022e-145	475.0	COG0612@1|root,COG0612@2|Bacteria,1ZT7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
GDHHQS3_k127_7975805_9	861299.J421_1270	2.253e-83	285.0	COG0106@1|root,COG0106@2|Bacteria,1ZSZJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS3_k127_7975805_12	861299.J421_1276	1.578e-59	212.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
GDHHQS3_k127_7975805_8	861299.J421_1278	8.382e-108	370.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CBP_BcsQ
GDHHQS3_k127_7975805_11	483219.LILAB_24465	5.18e-62	216.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,42WFV@68525|delta/epsilon subdivisions,2WS6B@28221|Deltaproteobacteria,2YUWV@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
GDHHQS3_k127_7977189_0	671143.DAMO_0749	9.138e-148	478.0	COG1222@1|root,COG2433@1|root,COG1222@2|Bacteria,COG2433@2|Bacteria,2NQB9@2323|unclassified Bacteria	2|Bacteria	O	Proteasomal ATPase OB/ID domain	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	2.7.13.3	ko:K07184,ko:K07777,ko:K12065,ko:K13525,ko:K13527	ko02020,ko03050,ko04141,ko05134,map02020,map03050,map04141,map05134	M00342,M00400,M00403,M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02044,ko03019,ko03051,ko04131,ko04147	3.A.16.1,3.A.7.11.1	-	-	AAA,Prot_ATP_ID_OB
GDHHQS3_k127_7977189_2	1038867.AXAY01000023_gene4646	4.119e-23	108.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JQPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7977189_1	1380355.JNIJ01000037_gene5326	1.595e-70	248.0	COG3474@1|root,COG3474@2|Bacteria,1RI3E@1224|Proteobacteria,2U2DT@28211|Alphaproteobacteria,3JZ8R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome P460	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_P460
GDHHQS3_k127_7989002_2	1379270.AUXF01000003_gene3844	6.247e-11	66.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_7989002_0	861299.J421_2893	7.797e-86	295.0	2F044@1|root,33T7T@2|Bacteria	861299.J421_2893|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7989002_1	379066.GAU_0628	3.372e-39	148.0	COG0809@1|root,COG0809@2|Bacteria,1ZSV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS3_k127_7990040_0	861299.J421_3227	4.727e-226	706.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_7990040_1	379066.GAU_1595	1.3e-51	186.0	COG1576@1|root,COG1576@2|Bacteria,1ZTQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
GDHHQS3_k127_7990040_2	1118054.CAGW01000016_gene4534	1.626e-23	104.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HGZ2@91061|Bacilli,26SJY@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_7991316_4	1379270.AUXF01000006_gene312	7.442e-47	171.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_7991316_3	861299.J421_3210	7.418e-49	186.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
GDHHQS3_k127_7991316_1	1379270.AUXF01000006_gene310	1.956e-154	494.0	COG1186@1|root,COG1186@2|Bacteria,1ZTE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_7991316_0	379066.GAU_1579	5.172e-235	742.0	COG1190@1|root,COG1190@2|Bacteria,1ZT9X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_7991316_2	861299.J421_3213	3.524e-74	254.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS3_k127_7996654_1	861299.J421_2590	1.839e-158	509.0	COG0162@1|root,COG0162@2|Bacteria,1ZT43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS3_k127_7996654_0	861299.J421_2591	2.085e-233	735.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_8011275_0	1379270.AUXF01000004_gene2961	9.095e-188	599.0	COG0405@1|root,COG0405@2|Bacteria,1ZT0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_8011275_1	861299.J421_2835	4.922e-75	261.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8011275_2	861299.J421_2834	3.169e-12	68.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_8017681_1	682795.AciX8_2549	3.841e-24	113.0	COG1629@1|root,COG4771@2|Bacteria,3Y477@57723|Acidobacteria,2JHX2@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_8017681_0	1340493.JNIF01000003_gene1475	2.332e-68	238.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS3_k127_8032526_26	861299.J421_1167	2.093e-31	127.0	COG1475@1|root,COG1475@2|Bacteria,1ZSKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS3_k127_8032526_19	861299.J421_1169	2.559e-90	304.0	COG0327@1|root,COG0327@2|Bacteria,1ZTE0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
GDHHQS3_k127_8032526_29	861299.J421_1156	8.255e-30	130.0	2FE2S@1|root,3462V@2|Bacteria,1ZTZM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_21	1379698.RBG1_1C00001G1242	6.696e-77	276.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
GDHHQS3_k127_8032526_25	379066.GAU_0013	6.406e-54	209.0	COG0204@1|root,COG0204@2|Bacteria,1ZUGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS3_k127_8032526_0	861299.J421_1151	0.0	1332.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_8032526_16	861299.J421_1148	4.152e-106	360.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_11	379066.GAU_0008	9.404e-116	379.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8032526_14	861299.J421_1146	7.281e-111	366.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1146|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_23	861299.J421_1145	1.982e-74	254.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_8032526_22	861299.J421_1142	4.191e-76	266.0	COG2207@1|root,COG2207@2|Bacteria,1ZTPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS3_k127_8032526_3	861299.J421_1072	1.287e-208	652.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
GDHHQS3_k127_8032526_2	1379270.AUXF01000002_gene1190	8.811e-209	658.0	COG0593@1|root,COG0593@2|Bacteria,1ZSQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS3_k127_8032526_31	861299.J421_1070	9.071e-24	101.0	COG0230@1|root,COG0230@2|Bacteria,1ZU59@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS3_k127_8032526_32	861299.J421_1069	1.542e-23	106.0	COG0594@1|root,COG0594@2|Bacteria,1ZV89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS3_k127_8032526_30	41431.PCC8801_1730	1.208e-27	113.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,3KIEZ@43988|Cyanothece	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS3_k127_8032526_7	861299.J421_1067	3.514e-149	490.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS3_k127_8032526_18	861299.J421_1065	1.234e-91	308.0	COG2220@1|root,COG2220@2|Bacteria	861299.J421_1065|-	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_8	379066.GAU_3931	3.981e-140	460.0	COG0486@1|root,COG0486@2|Bacteria,1ZSRA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GDHHQS3_k127_8032526_9	1379270.AUXF01000002_gene1184	8.568e-139	454.0	COG5504@1|root,COG5504@2|Bacteria,1ZTCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_17	861299.J421_1061	7.286e-100	332.0	COG1655@1|root,COG1655@2|Bacteria,1ZSTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
GDHHQS3_k127_8032526_13	861299.J421_1060	2.283e-111	362.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
GDHHQS3_k127_8032526_1	861299.J421_1939	1.017e-212	668.0	COG1236@1|root,COG1236@2|Bacteria,1ZSP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
GDHHQS3_k127_8032526_24	861299.J421_0929	1.088e-58	210.0	COG1434@1|root,COG1434@2|Bacteria,1ZTZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS3_k127_8032526_4	861299.J421_0928	1.265e-192	611.0	COG0612@1|root,COG0612@2|Bacteria,1ZTAP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_8032526_6	861299.J421_0927	2.989e-161	521.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_8032526_27	1541065.JRFE01000004_gene5334	2.367e-30	131.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,3VJ50@52604|Pleurocapsales	1117|Cyanobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,PhoPQ_related
GDHHQS3_k127_8032526_5	861299.J421_0916	1.28e-188	605.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_8032526_10	861299.J421_0915	1.017e-138	455.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_8032526_20	861299.J421_0908	3.21e-80	271.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS3_k127_8032526_15	861299.J421_0907	3.556e-109	357.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_8032526_28	861299.J421_0906	5.357e-30	126.0	2FFVA@1|root,347SB@2|Bacteria,1ZTX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8032526_12	379066.GAU_3913	7.621e-112	372.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS3_k127_8046229_2	317936.Nos7107_2777	6.164e-60	216.0	COG3485@1|root,COG3485@2|Bacteria,1G538@1117|Cyanobacteria,1HQQI@1161|Nostocales	1117|Cyanobacteria	Q	COGs COG3485 Protocatechuate 3 4-dioxygenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
GDHHQS3_k127_8046229_3	309801.trd_A0609	3.618e-43	166.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_8046229_1	861299.J421_0377	1.518e-69	243.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.45,4.1.2.14,4.1.3.42	ko:K00874,ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R01541,R05605	RC00002,RC00017,RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS3_k127_8046229_0	1121920.AUAU01000018_gene1783	1.663e-110	366.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_8047_2	383372.Rcas_2650	7.375e-11	70.0	COG1864@1|root,COG1864@2|Bacteria	2|Bacteria	F	neuron death in response to oxidative stress	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclea_NS_2,Endonuclease_NS,Excalibur
GDHHQS3_k127_8047_0	8496.XP_006262675.1	1.84e-36	150.0	COG1864@1|root,KOG3721@2759|Eukaryota,38E5K@33154|Opisthokonta,3BD2Y@33208|Metazoa,3CVAJ@33213|Bilateria,485XE@7711|Chordata,490AJ@7742|Vertebrata	33208|Metazoa	F	neuron death in response to oxidative stress	ENDOG	GO:0000001,GO:0000003,GO:0000737,GO:0001701,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004536,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006308,GO:0006309,GO:0006310,GO:0006401,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006996,GO:0007005,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009790,GO:0009792,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010604,GO:0010623,GO:0010941,GO:0010942,GO:0012501,GO:0016043,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022411,GO:0022412,GO:0022414,GO:0030154,GO:0030262,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032501,GO:0032502,GO:0032504,GO:0034097,GO:0034612,GO:0034641,GO:0034645,GO:0034655,GO:0035234,GO:0036477,GO:0042221,GO:0042802,GO:0042803,GO:0042981,GO:0043009,GO:0043025,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044297,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045935,GO:0046483,GO:0046677,GO:0046700,GO:0046983,GO:0048232,GO:0048308,GO:0048311,GO:0048468,GO:0048515,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0097194,GO:0097458,GO:0140097,GO:0140098,GO:1900117,GO:1900119,GO:1900407,GO:1900409,GO:1901031,GO:1901033,GO:1901298,GO:1901300,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576,GO:1902510,GO:1902512,GO:1902882,GO:1902884,GO:1903201,GO:1903205,GO:1903209,GO:1903624,GO:1903626,GO:1905206,GO:2001023,GO:2001025,GO:2001038,GO:2001040	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
GDHHQS3_k127_8047_1	1337936.IJ00_00910	7.999e-18	98.0	2EFPZ@1|root,339G0@2|Bacteria,1GCBN@1117|Cyanobacteria,1HIZK@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8069895_1	251221.35211322	2.631e-111	368.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GDHHQS3_k127_8069895_2	861299.J421_1513	1.167e-26	119.0	2CWY1@1|root,32T0M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8069895_0	945713.IALB_2970	2.873e-163	533.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_8071229_4	861299.J421_2545	6.844e-115	382.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS3_k127_8071229_1	861299.J421_2544	4.022e-182	600.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_8071229_0	861299.J421_2541	2.137e-209	663.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_8071229_3	861299.J421_2540	2.474e-154	491.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_8071229_5	861299.J421_3670	2.024e-98	334.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
GDHHQS3_k127_8071229_6	861299.J421_3671	9.967e-77	265.0	2F2ZI@1|root,33VUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8071229_2	861299.J421_3672	7.855e-169	539.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8097157_6	748280.NH8B_2505	2.806e-89	308.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,2VW3K@28216|Betaproteobacteria,2KTP8@206351|Neisseriales	206351|Neisseriales	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS3_k127_8097157_3	748280.NH8B_2507	3.286e-171	542.0	COG2175@1|root,COG2175@2|Bacteria,1MWQ6@1224|Proteobacteria,2VKNN@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Taurine catabolism dioxygenase TauD TfdA	-	-	-	-	-	-	-	-	-	-	-	-	TauD
GDHHQS3_k127_8097157_1	748280.NH8B_2508	0.0	1290.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
GDHHQS3_k127_8097157_0	748280.NH8B_2509	0.0	1325.0	COG0110@1|root,COG0110@2|Bacteria,1QYE2@1224|Proteobacteria,2WHE2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS3_k127_8097157_2	279714.FuraDRAFT_0941	5.765e-174	550.0	COG2423@1|root,COG2423@2|Bacteria,1NC53@1224|Proteobacteria,2VKZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ornithine cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_8097157_5	748280.NH8B_2511	3.689e-166	530.0	COG0031@1|root,COG0031@2|Bacteria,1MVGX@1224|Proteobacteria,2WFP0@28216|Betaproteobacteria	28216|Betaproteobacteria	E	cysteine biosynthetic process from serine	sbnA	-	2.5.1.140	ko:K21949	-	-	R11705	-	ko00000,ko01000	-	-	-	PALP
GDHHQS3_k127_8097157_7	1040989.AWZU01000022_gene4700	6.25e-26	108.0	COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,2U8J8@28211|Alphaproteobacteria,3JZ7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_8097157_4	420662.Mpe_A1307	1.795e-166	533.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,1KK66@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GDHHQS3_k127_8098_1	861299.J421_6044	7.666e-247	775.0	COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS3_k127_8098_12	82654.Pse7367_2151	0.0001298	49.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria,1HB8R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8098_9	998674.ATTE01000001_gene3668	2.61e-14	74.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,1SHN2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8098_2	1379270.AUXF01000004_gene3158	4.5e-145	481.0	COG2755@1|root,COG2755@2|Bacteria,1ZUW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_8098_3	1379270.AUXF01000004_gene3155	3.181e-124	419.0	28PJE@1|root,2ZC90@2|Bacteria,1ZTV5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
GDHHQS3_k127_8098_0	1379270.AUXF01000004_gene3156	0.0	1085.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1ZTBA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8098_5	1379270.AUXF01000004_gene3157	8.102e-63	231.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8098_8	637905.SVI_2131	1.439e-16	89.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QAS3@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidase inhibitor I9	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PPC,Peptidase_S8
GDHHQS3_k127_8098_6	592029.DDD_0935	2.346e-51	192.0	COG5266@1|root,COG5266@2|Bacteria,4NI88@976|Bacteroidetes,1I0C0@117743|Flavobacteriia,3HKZW@363408|Nonlabens	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
GDHHQS3_k127_8098_4	1294273.roselon_01710	1.273e-68	252.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_8098_7	861299.J421_1746	1.624e-21	106.0	2CKIA@1|root,345C4@2|Bacteria,1ZV3S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS3_k127_8098_11	861299.J421_1745	3.668e-09	62.0	28Y4A@1|root,2ZJZS@2|Bacteria,1ZV7B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8139346_2	365044.Pnap_4011	5.604e-144	479.0	COG0557@1|root,COG0557@2|Bacteria,1NI95@1224|Proteobacteria,2VNKE@28216|Betaproteobacteria,4AA79@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
GDHHQS3_k127_8139346_8	452637.Oter_1314	0.0003314	43.0	COG5507@1|root,COG5507@2|Bacteria,46VQ8@74201|Verrucomicrobia,3K9QM@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
GDHHQS3_k127_8139346_6	1038859.AXAU01000013_gene6598	1.151e-27	113.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS3_k127_8139346_3	1267535.KB906767_gene1445	3.555e-97	323.0	2CDZB@1|root,2ZBFS@2|Bacteria,3Y5HH@57723|Acidobacteria,2JM8W@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8139346_1	204669.Acid345_1863	1.711e-176	571.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,3Y2G4@57723|Acidobacteria,2JIJC@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
GDHHQS3_k127_8139346_5	1267535.KB906767_gene19	2.38e-33	147.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene19|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8139346_4	543728.Vapar_4999	1.791e-41	157.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_8139346_0	1121123.AUAO01000003_gene2364	3.14e-214	685.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2KI6R@204458|Caulobacterales	204458|Caulobacterales	E	leukotriene A-4 hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS3_k127_8139346_7	379066.GAU_2138	1.858e-15	79.0	COG2859@1|root,COG2859@2|Bacteria,1ZUNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_8172766_0	861299.J421_0887	0.0	1202.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8172766_1	861299.J421_0886	5.255e-20	89.0	COG1595@1|root,COG1595@2|Bacteria,1ZUWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GDHHQS3_k127_8187023_1	1379270.AUXF01000001_gene2648	1.046e-42	166.0	COG0589@1|root,COG0589@2|Bacteria,1ZTUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_8187023_0	861299.J421_4364	3.293e-206	651.0	COG1914@1|root,COG1914@2|Bacteria,1ZT3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
GDHHQS3_k127_8187023_2	1408473.JHXO01000013_gene586	0.0004221	50.0	COG4244@1|root,COG4244@2|Bacteria,4NPYK@976|Bacteroidetes,2FYNE@200643|Bacteroidia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
GDHHQS3_k127_8229240_7	861299.J421_2084	2.983e-45	168.0	COG0822@1|root,COG0822@2|Bacteria,1ZTSD@142182|Gemmatimonadetes	2|Bacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS3_k127_8229240_2	861299.J421_2085	3.723e-186	589.0	COG0520@1|root,COG0520@2|Bacteria,1ZSYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_8229240_13	67257.JODR01000012_gene6086	5.072e-20	95.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_8229240_0	861299.J421_2090	7.63e-268	829.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_8229240_4	1379270.AUXF01000001_gene2395	5.952e-125	406.0	COG0396@1|root,COG0396@2|Bacteria,1ZSRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS3_k127_8229240_3	861299.J421_2088	1.116e-132	442.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_8229240_18	383372.Rcas_2521	2.897e-07	59.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_8229240_15	1396141.BATP01000051_gene3338	1.687e-17	85.0	2EKH8@1|root,33E79@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8229240_9	1379270.AUXF01000001_gene2240	1.248e-36	147.0	COG4875@1|root,COG4875@2|Bacteria,1ZTYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GDHHQS3_k127_8229240_6	861299.J421_2835	1.178e-64	233.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8229240_12	682795.AciX8_1075	3.074e-23	107.0	COG1476@1|root,COG1476@2|Bacteria,3Y5P8@57723|Acidobacteria,2JJXV@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS3_k127_8229240_17	1207075.PputUW4_01882	8.574e-08	59.0	2E3S2@1|root,32YPN@2|Bacteria,1NDK1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8229240_1	1487953.JMKF01000043_gene2596	7.793e-197	625.0	COG0422@1|root,COG0422@2|Bacteria,1G2N9@1117|Cyanobacteria,1H931@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
GDHHQS3_k127_8229240_10	1379270.AUXF01000001_gene2399	1.141e-35	144.0	COG0739@1|root,COG0739@2|Bacteria,1ZTXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS3_k127_8229240_11	861299.J421_2103	7.121e-34	137.0	COG1534@1|root,COG1534@2|Bacteria,1ZU26@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
GDHHQS3_k127_8229240_8	861299.J421_2106	1.199e-43	161.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
GDHHQS3_k127_8229240_5	1122604.JONR01000067_gene4214	3.271e-73	256.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1X6I7@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
GDHHQS3_k127_8229240_14	1379270.AUXF01000001_gene2402	9.917e-20	90.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8250197_2	1121378.KB899704_gene2420	8.696e-31	130.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_8250197_1	1121920.AUAU01000013_gene1716	3.873e-84	287.0	COG4313@1|root,COG4313@2|Bacteria,3Y7K3@57723|Acidobacteria	57723|Acidobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8250197_0	309801.trd_0484	1.842e-165	531.0	COG1282@1|root,COG1282@2|Bacteria,2GB8C@200795|Chloroflexi,27Y0C@189775|Thermomicrobia	189775|Thermomicrobia	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
GDHHQS3_k127_8270805_1	1122621.ATZA01000059_gene4162	5.927e-34	144.0	COG1680@1|root,COG1680@2|Bacteria,4NTSD@976|Bacteroidetes,1IVGF@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_8270805_2	1144275.COCOR_03440	6.934e-11	64.0	2AIWT@1|root,319EE@2|Bacteria,1Q2HH@1224|Proteobacteria,43E60@68525|delta/epsilon subdivisions,2WZUD@28221|Deltaproteobacteria,2Z2RZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS3_k127_8270805_0	525897.Dbac_1184	2.404e-67	235.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
GDHHQS3_k127_8274854_1	861299.J421_3918	5.803e-243	757.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GDHHQS3_k127_8274854_0	861299.J421_5982	1.743e-302	960.0	COG1629@1|root,COG1629@2|Bacteria,1ZV2K@142182|Gemmatimonadetes	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
GDHHQS3_k127_8274854_4	926560.KE387023_gene3760	2.421e-24	113.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Malectin
GDHHQS3_k127_8274854_2	1267535.KB906767_gene2352	2.557e-148	483.0	COG4975@1|root,COG4975@2|Bacteria	2|Bacteria	G	carbohydrate transmembrane transporter activity	glcU	GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659	-	ko:K05340,ko:K06216	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Sugar_transport
GDHHQS3_k127_8274854_3	204669.Acid345_2325	2.924e-119	389.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_8277190_4	1379270.AUXF01000001_gene2822	1.811e-25	116.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_8277190_1	861299.J421_4162	3.366e-126	426.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS3_k127_8277190_0	861299.J421_4163	4.296e-140	454.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GDHHQS3_k127_8277190_2	861299.J421_4164	9.907e-93	315.0	COG0767@1|root,COG0767@2|Bacteria,1ZSUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS3_k127_8277190_3	1379270.AUXF01000001_gene2817	3.403e-39	161.0	COG1463@1|root,COG1463@2|Bacteria,1ZTI5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS3_k127_8296128_1	861299.J421_3907	5.805e-103	340.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS3_k127_8296128_0	861299.J421_3906	2.182e-263	818.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GDHHQS3_k127_8296128_2	1379270.AUXF01000003_gene3487	1.251e-78	269.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_8300395_1	861299.J421_2927	3.038e-68	241.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
GDHHQS3_k127_8300395_2	861299.J421_2925	1.679e-59	210.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS3_k127_8300395_0	861299.J421_2922	1.915e-139	447.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_8300395_3	861299.J421_2921	3.931e-44	164.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS3_k127_8311620_0	861299.J421_3416	2.302e-93	314.0	COG2265@1|root,COG2265@2|Bacteria,1ZSPC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
GDHHQS3_k127_8311620_3	861299.J421_3415	1.545e-49	185.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS3_k127_8311620_1	1379270.AUXF01000006_gene117	3.63e-70	241.0	COG0102@1|root,COG0102@2|Bacteria,1ZTIS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS3_k127_8311620_2	861299.J421_3413	1.943e-60	210.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS3_k127_8311620_4	1379270.AUXF01000006_gene119	5.436e-12	67.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS3_k127_8321016_1	861299.J421_3843	6.144e-195	621.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1ZTH0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FPT	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GDHHQS3_k127_8321016_2	1242864.D187_005262	9.178e-75	265.0	COG1409@1|root,COG1409@2|Bacteria,1RJ6Z@1224|Proteobacteria	1224|Proteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_8321016_3	1123277.KB893207_gene411	4.387e-22	108.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,47NSY@768503|Cytophagia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
GDHHQS3_k127_8321016_4	161528.ED21_20779	5.839e-22	109.0	2FGC9@1|root,3488G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
GDHHQS3_k127_8321016_0	861299.J421_2748	4.839e-294	909.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS3_k127_8339430_6	861299.J421_2696	3.355e-52	187.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GDHHQS3_k127_8339430_9	379066.GAU_0773	1.223e-25	119.0	2FF43@1|root,34729@2|Bacteria,1ZTX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8339430_0	861299.J421_2694	3e-323	998.0	COG0433@1|root,COG0433@2|Bacteria,1ZURZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_8339430_4	861299.J421_2693	3.789e-91	310.0	COG2380@1|root,COG2380@2|Bacteria,1ZUZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8339430_8	861299.J421_2691	5.755e-32	132.0	COG1522@1|root,COG1522@2|Bacteria,1ZU0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS3_k127_8339430_2	861299.J421_2689	2.883e-108	370.0	COG0513@1|root,COG0513@2|Bacteria,1ZTQP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DbpA
GDHHQS3_k127_8339430_3	861299.J421_2688	2.868e-95	318.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GDHHQS3_k127_8339430_5	861299.J421_2687	7.709e-73	255.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GDHHQS3_k127_8339430_7	1379270.AUXF01000004_gene3114	3.031e-48	176.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_8339430_1	861299.J421_2251	1.681e-162	518.0	COG3525@1|root,COG3525@2|Bacteria,1ZUG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
GDHHQS3_k127_8357423_8	518766.Rmar_1736	6.331e-45	171.0	2CDAN@1|root,3134Z@2|Bacteria,4PJ1R@976|Bacteroidetes,1FK60@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
GDHHQS3_k127_8357423_1	518766.Rmar_1737	2.279e-236	745.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1FJXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GMC oxidoreductase	betA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_8357423_5	518766.Rmar_0423	1.027e-99	334.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS3_k127_8357423_3	861299.J421_6265	1.661e-146	471.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
GDHHQS3_k127_8357423_7	643648.Slip_0761	2.461e-64	235.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
GDHHQS3_k127_8357423_2	861299.J421_6264	1.227e-152	494.0	COG2152@1|root,COG2152@2|Bacteria	861299.J421_6264|-	G	transferase activity, transferring glycosyl groups	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	-
GDHHQS3_k127_8357423_0	861299.J421_6263	0.0	1095.0	COG1331@1|root,COG1653@1|root,COG1331@2|Bacteria,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	DUF4861,SBP_bac_8
GDHHQS3_k127_8357423_6	518766.Rmar_0359	2.329e-88	299.0	COG1175@1|root,COG1175@2|Bacteria,4PFAK@976|Bacteroidetes,1FKDC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17322	ko02010,map02010	M00207,M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.35	-	-	BPD_transp_1
GDHHQS3_k127_8357423_4	861299.J421_6261	5.96e-129	417.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	ycjP_4	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_8357423_9	861299.J421_6260	5.381e-19	87.0	COG3842@1|root,COG3842@2|Bacteria,1ZU03@142182|Gemmatimonadetes	2|Bacteria	E	ABC transporter	-	-	-	ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_8367123_2	1379270.AUXF01000001_gene2771	4.007e-17	83.0	COG1048@1|root,COG1048@2|Bacteria,1ZTE7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_8367123_1	861299.J421_4225	3.932e-122	403.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
GDHHQS3_k127_8367123_0	861299.J421_4222	3.831e-160	515.0	COG3844@1|root,COG3844@2|Bacteria,1ZTZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_8399450_2	1449357.JQLK01000001_gene419	6.059e-74	254.0	COG1117@1|root,COG1117@2|Bacteria,1WI7W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_8399450_1	1131812.JQMS01000001_gene1241	9.478e-106	350.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia,2NSSM@237|Flavobacterium	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_8399450_4	379066.GAU_2370	7.281e-71	250.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS3_k127_8399450_0	379066.GAU_2373	2.748e-146	470.0	COG0306@1|root,COG0306@2|Bacteria,1ZSZ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS3_k127_8399450_3	861299.J421_3846	9.8e-73	250.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS3_k127_8399450_5	1242864.D187_002187	1.855e-24	104.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_8438628_9	861299.J421_0291	1.449e-28	122.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS3_k127_8438628_11	379066.GAU_2523	2.171e-18	89.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_8438628_7	338963.Pcar_1179	9.046e-41	167.0	COG2206@1|root,COG2206@2|Bacteria,1RE2G@1224|Proteobacteria,42S6Z@68525|delta/epsilon subdivisions,2WNCP@28221|Deltaproteobacteria,43TC7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cyclic diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_8438628_12	243231.GSU0698	7.634e-18	98.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_8438628_3	861299.J421_0488	3.201e-156	502.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8438628_10	404589.Anae109_2038	3.713e-21	98.0	COG1970@1|root,COG1970@2|Bacteria	2|Bacteria	M	mechanosensitive ion channel activity	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS3_k127_8438628_8	1038860.AXAP01000005_gene8006	8.871e-30	128.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TX72@28211|Alphaproteobacteria,3K3KE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
GDHHQS3_k127_8438628_6	1396418.BATQ01000005_gene1388	1.812e-45	177.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS3_k127_8438628_0	1379270.AUXF01000001_gene2645	3.397e-196	647.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GDHHQS3_k127_8438628_2	861299.J421_0892	2.024e-166	539.0	COG0076@1|root,COG0076@2|Bacteria,1ZTFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
GDHHQS3_k127_8438628_5	861299.J421_1157	7.918e-75	261.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GDHHQS3_k127_8438628_4	861299.J421_0110	8.339e-135	442.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_8438628_1	861299.J421_1941	1.18e-180	582.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_8442710_1	861299.J421_3602	1.222e-70	245.0	COG0558@1|root,COG0558@2|Bacteria,1ZTIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_8442710_0	861299.J421_3601	1.217e-256	794.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GDHHQS3_k127_8442710_3	379066.GAU_1996	2.093e-29	132.0	296W8@1|root,2ZU51@2|Bacteria,1ZU4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8442710_2	1379270.AUXF01000003_gene3861	1.346e-31	131.0	2FD8C@1|root,345AC@2|Bacteria,1ZTXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_84966_3	479434.Sthe_1947	6.439e-15	76.0	COG1282@1|root,COG1282@2|Bacteria,2GB8C@200795|Chloroflexi,27Y0C@189775|Thermomicrobia	189775|Thermomicrobia	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
GDHHQS3_k127_84966_2	479434.Sthe_1946	3.55e-33	143.0	COG3288@1|root,COG3288@2|Bacteria,2GBAD@200795|Chloroflexi,27YI1@189775|Thermomicrobia	189775|Thermomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
GDHHQS3_k127_84966_0	1382356.JQMP01000004_gene541	2.902e-138	449.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS3_k127_84966_1	861299.J421_2623	1.945e-46	181.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD,OmpA
GDHHQS3_k127_8507264_2	379066.GAU_2364	1.744e-15	89.0	2ES4T@1|root,33JPM@2|Bacteria,1ZU4W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8507264_1	1379270.AUXF01000003_gene3564	2.706e-135	447.0	COG5492@1|root,COG5492@2|Bacteria,1ZSN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8507264_0	861299.J421_1890	1.863e-257	822.0	COG1629@1|root,COG4771@2|Bacteria,1ZT3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8508701_1	1379270.AUXF01000001_gene2553	1.174e-146	468.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_8508701_0	861299.J421_4449	3.016e-182	590.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8508701_2	1118054.CAGW01000082_gene3065	3.474e-76	270.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,26T8W@186822|Paenibacillaceae	91061|Bacilli	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
GDHHQS3_k127_8514369_2	1173026.Glo7428_4364	6.674e-06	50.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HCBP_related,HemolysinCabind
GDHHQS3_k127_8514369_1	522306.CAP2UW1_1322	2.779e-71	244.0	COG5606@1|root,COG5606@2|Bacteria,1QUS2@1224|Proteobacteria,2VRXG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
GDHHQS3_k127_8514369_0	1349767.GJA_2172	1.739e-72	253.0	COG5654@1|root,COG5654@2|Bacteria,1N277@1224|Proteobacteria,2VMJ6@28216|Betaproteobacteria,4762S@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
GDHHQS3_k127_8565898_7	1379270.AUXF01000001_gene2402	3.337e-71	244.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8565898_12	861299.J421_2107	3.353e-35	139.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2
GDHHQS3_k127_8565898_2	1379270.AUXF01000001_gene2405	4.917e-158	506.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS3_k127_8565898_11	861299.J421_2112	5.605e-41	154.0	COG2151@1|root,COG2151@2|Bacteria,1ZTUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS3_k127_8565898_1	861299.J421_2113	5.642e-160	516.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_8565898_6	1379270.AUXF01000001_gene2409	1.866e-72	249.0	COG1595@1|root,COG1595@2|Bacteria,1ZTJF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_8565898_15	861299.J421_2115	1.761e-19	96.0	2F7PW@1|root,34048@2|Bacteria,1ZTZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8565898_16	1247963.JPHU01000008_gene2779	1.081e-07	63.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	dop	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_8565898_5	861299.J421_2117	7.344e-113	373.0	COG0492@1|root,COG0492@2|Bacteria,1ZV3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GDHHQS3_k127_8565898_0	861299.J421_4036	8.167e-244	773.0	COG4774@1|root,COG4774@2|Bacteria,1ZTSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_8565898_3	861299.J421_3233	3.949e-125	413.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GDHHQS3_k127_8565898_8	1032480.MLP_05660	3.478e-62	224.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria,4DP0G@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase,QueC
GDHHQS3_k127_8565898_10	1167006.UWK_01647	1.684e-42	171.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,2MJ1E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GDHHQS3_k127_8565898_4	379066.GAU_2868	1.391e-121	400.0	COG1600@1|root,COG1600@2|Bacteria,1ZU4X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
GDHHQS3_k127_8565898_14	1379270.AUXF01000001_gene2453	2.271e-25	108.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8565898_9	861299.J421_3903	7.047e-57	202.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
GDHHQS3_k127_8565898_13	582515.KR51_00001160	1.161e-26	117.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS3_k127_8573996_11	861299.J421_3012	5.579e-16	79.0	COG2919@1|root,COG2919@2|Bacteria,1ZU6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Septum formation initiator	-	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
GDHHQS3_k127_8573996_0	861299.J421_3011	8.457e-216	676.0	COG0148@1|root,COG0148@2|Bacteria,1ZTAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS3_k127_8573996_6	861299.J421_3010	7.797e-86	295.0	COG0204@1|root,COG0204@2|Bacteria,1ZT6D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_8573996_7	861299.J421_3009	1.926e-82	287.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_8573996_5	861299.J421_3008	1.923e-114	392.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1ZTAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GDHHQS3_k127_8573996_8	861299.J421_3006	3.556e-55	197.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8573996_1	379066.GAU_1295	2.568e-197	623.0	COG0112@1|root,COG0112@2|Bacteria,1ZT5K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS3_k127_8573996_9	379066.GAU_1294	1.563e-52	189.0	COG0698@1|root,COG0698@2|Bacteria,1ZUTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS3_k127_8573996_3	861299.J421_3004	4.872e-160	511.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_8573996_2	861299.J421_3003	2.011e-177	562.0	COG1960@1|root,COG1960@2|Bacteria,1ZSRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8573996_4	1379270.AUXF01000005_gene596	2.313e-126	416.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS3_k127_8573996_10	861299.J421_3001	5.312e-34	134.0	COG1266@1|root,COG1266@2|Bacteria,1ZTXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_8622504_1	861299.J421_5612	5.062e-70	248.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
GDHHQS3_k127_8622504_0	861299.J421_3940	1.403e-72	250.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_88937_7	1379270.AUXF01000006_gene169	7.884e-124	407.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_88937_10	1379270.AUXF01000006_gene170	1.725e-79	276.0	COG0159@1|root,COG0159@2|Bacteria,1ZSYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS3_k127_88937_16	861299.J421_3361	1.227e-22	101.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB2	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
GDHHQS3_k127_88937_15	1123300.AUIN01000009_gene303	1.79e-28	124.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GDHHQS3_k127_88937_9	868864.Dester_0331	7.672e-88	297.0	COG0413@1|root,COG0413@2|Bacteria,2G3PI@200783|Aquificae	200783|Aquificae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GDHHQS3_k127_88937_11	1121934.AUDX01000007_gene1876	2.235e-71	252.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4FN3G@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS3_k127_88937_12	861299.J421_3360	5.464e-70	241.0	COG0801@1|root,COG1713@1|root,COG0801@2|Bacteria,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS3_k127_88937_5	861299.J421_3358	2.106e-154	495.0	COG0820@1|root,COG0820@2|Bacteria,1ZTAJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
GDHHQS3_k127_88937_3	861299.J421_3356	1.092e-238	765.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_88937_6	861299.J421_3355	2.18e-142	459.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS3_k127_88937_14	861299.J421_3353	1.264e-36	143.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS3_k127_88937_4	861299.J421_3350	9.668e-155	497.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS3_k127_88937_0	861299.J421_3349	8.133e-296	919.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_88937_8	861299.J421_3348	8.459e-122	395.0	COG0500@1|root,COG2226@2|Bacteria,1ZTCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_88937_13	861299.J421_3347	4.425e-69	236.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS3_k127_88937_1	861299.J421_3346	3.788e-266	836.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS3_k127_88937_2	861299.J421_3345	1.305e-243	760.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS3_k127_88937_17	379066.GAU_1705	4.449e-10	60.0	2CIU6@1|root,32S8H@2|Bacteria,1ZTUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8932478_2	861299.J421_3773	2.423e-72	256.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_8932478_0	861299.J421_4469	0.0	1056.0	COG1913@1|root,COG1913@2|Bacteria,1ZT1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
GDHHQS3_k127_8932478_1	1123508.JH636446_gene6369	2.644e-153	518.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_8938775_2	1384054.N790_01715	1.338e-36	145.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,1X7ZV@135614|Xanthomonadales	135614|Xanthomonadales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_8938775_3	153721.MYP_4620	1.549e-08	64.0	2EKCZ@1|root,33E39@2|Bacteria,4NXWT@976|Bacteroidetes,47VYQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8938775_0	861299.J421_4121	2.043e-273	859.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS3_k127_8938775_1	861299.J421_4120	2.2e-59	211.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS3_k127_918683_4	379066.GAU_1888	3.853e-21	94.0	COG0742@1|root,COG0742@2|Bacteria,1ZTVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS3_k127_918683_1	1379270.AUXF01000006_gene73	2.442e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,1ZTTQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_918683_0	861299.J421_3456	2.469e-87	297.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GDHHQS3_k127_918683_2	861299.J421_3455	7.113e-54	190.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS3_k127_918683_3	861299.J421_3454	3.391e-33	134.0	COG2172@1|root,COG2172@2|Bacteria,1ZU34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS3_k127_939579_5	861299.J421_1416	1.162e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_939579_2	861299.J421_1418	4.711e-75	278.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	2|Bacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT,HEAT_2,Paired_CXXCH_1,Peptidase_M56,TPR_19,TPR_8
GDHHQS3_k127_939579_1	861299.J421_1419	1.229e-102	350.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_939579_4	1379270.AUXF01000007_gene892	8.019e-26	116.0	COG1246@1|root,COG1246@2|Bacteria,1ZTT2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GDHHQS3_k127_939579_0	234267.Acid_7087	5.709e-130	435.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
## 2673 queries scanned
## Total time (seconds): 92.32006645202637
## Rate: 28.95 q/s