## Sat Nov 16 14:27:15 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin3/GDHHQS_3_bin.52.fa -m mmseqs --itype genome -o GDHHQS_3_bin.52 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/GDHHQS_3_bin.52 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS3_k127_1012858_0	861299.J421_3809	1.938e-144	470.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS3_k127_1012858_1	357808.RoseRS_0608	1.891e-27	122.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
GDHHQS3_k127_1031169_2	196367.JNFG01000214_gene1275	2.757e-62	224.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria,2WH3B@28216|Betaproteobacteria,1KIHJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_1031169_1	1123504.JQKD01000012_gene1372	1.078e-75	266.0	COG3384@1|root,COG3384@2|Bacteria,1PVHA@1224|Proteobacteria,2WBB4@28216|Betaproteobacteria,4AHWW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
GDHHQS3_k127_1031169_4	1122611.KB903947_gene891	4.053e-18	92.0	COG1309@1|root,COG1309@2|Bacteria,2IMV7@201174|Actinobacteria,4EQVI@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_1031169_3	266779.Meso_1055	4.695e-29	125.0	COG0697@1|root,COG2510@1|root,COG0697@2|Bacteria,COG2510@2|Bacteria,1Q6VT@1224|Proteobacteria,2USD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_1039244_0	1313172.YM304_26310	9.443e-86	294.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CMXM@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_1039244_1	383372.Rcas_3343	7.299e-30	121.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_105788_1	479434.Sthe_2925	4.758e-16	91.0	COG0747@1|root,COG0747@2|Bacteria,2GA2U@200795|Chloroflexi,27YVV@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_105788_0	357808.RoseRS_1113	3.026e-78	275.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,375EE@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_105788_2	479434.Sthe_0909	2.254e-05	56.0	2BHS8@1|root,33DMI@2|Bacteria,2GBGN@200795|Chloroflexi,27YQG@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
GDHHQS3_k127_1066723_0	311424.DhcVS_1064	3.845e-134	446.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,34CKB@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS3_k127_1092567_0	243164.DET0337	2.086e-80	288.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,34D0F@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Helicase_C,ResIII
GDHHQS3_k127_1092567_1	331869.BAL199_08898	1.418e-41	171.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1103376_2	501479.ACNW01000115_gene3939	5.461e-07	53.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS3_k127_1103376_1	1123248.KB893322_gene687	4.336e-10	70.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,4NKF1@976|Bacteroidetes	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
GDHHQS3_k127_1103376_0	1231391.AMZF01000094_gene105	3.724e-104	350.0	COG1063@1|root,COG1063@2|Bacteria,1MXHK@1224|Proteobacteria,2W9GK@28216|Betaproteobacteria,3T7Q9@506|Alcaligenaceae	28216|Betaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_1114998_2	219305.MCAG_00517	1.73e-25	110.0	COG0529@1|root,COG0529@2|Bacteria,2I4MW@201174|Actinobacteria	201174|Actinobacteria	P	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GDHHQS3_k127_1114998_0	1121472.AQWN01000008_gene2037	5.321e-102	342.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS3_k127_1114998_1	485916.Dtox_3967	3.386e-38	147.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS3_k127_1115029_0	543728.Vapar_1687	4.161e-128	423.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VRUP@28216|Betaproteobacteria,4AJ7Z@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
GDHHQS3_k127_1115029_1	1157637.KB892109_gene4381	5.472e-16	81.0	COG1686@1|root,COG1686@2|Bacteria,2GM2X@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase S11 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
GDHHQS3_k127_1129760_1	383372.Rcas_4446	7.979e-39	149.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,3757K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
GDHHQS3_k127_1129760_4	1123386.AUIW01000008_gene1914	0.0001341	45.0	COG1724@1|root,COG1724@2|Bacteria,1WKHH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_1129760_2	1089553.Tph_c01960	3.607e-14	75.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_1129760_0	552811.Dehly_0299	5.119e-137	447.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi,34CYU@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_1129760_3	485913.Krac_6670	1.602e-12	72.0	2CJPB@1|root,33JM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1145897_1	326427.Cagg_2791	7.114e-47	172.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376GY@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_1145897_0	1089550.ATTH01000001_gene978	2.579e-72	259.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1FIR3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GK	ROK family	nagC	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
GDHHQS3_k127_1145897_2	909663.KI867150_gene2096	8.742e-37	141.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_1147116_1	1382306.JNIM01000001_gene623	3.44e-111	373.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_1147116_3	469383.Cwoe_0175	3.652e-43	180.0	COG1921@1|root,COG1921@2|Bacteria,2GNZX@201174|Actinobacteria	201174|Actinobacteria	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
GDHHQS3_k127_1147116_2	1187851.A33M_4340	1.149e-99	331.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,3FDGW@34008|Rhodovulum	28211|Alphaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
GDHHQS3_k127_1147116_0	1382306.JNIM01000001_gene3556	6.196e-273	857.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS3_k127_1186139_1	314230.DSM3645_16165	1.155e-21	100.0	2DNKJ@1|root,32XZB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1186139_0	243164.DET1550	7.471e-166	537.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi,34CT7@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS3_k127_1207123_2	266117.Rxyl_2548	4.451e-111	368.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS3_k127_1207123_0	517418.Ctha_2180	6.563e-133	443.0	COG1249@1|root,COG1249@2|Bacteria,1FDB4@1090|Chlorobi	1090|Chlorobi	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_1207123_4	28042.GU90_10220	1.61e-74	263.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4E13H@85010|Pseudonocardiales	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_1207123_7	926569.ANT_10990	1.489e-21	100.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS3_k127_1207123_3	309801.trd_0542	3.48e-107	353.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi,27XY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_1207123_1	357808.RoseRS_1611	7.534e-122	405.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_1207123_6	351160.LRC548	5.61e-33	139.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
GDHHQS3_k127_1207123_8	368407.Memar_0185	4.044e-10	68.0	COG1898@1|root,arCOG04188@2157|Archaea,2XWJQ@28890|Euryarchaeota,2NASX@224756|Methanomicrobia	224756|Methanomicrobia	M	WxcM-like, C-terminal	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS3_k127_1207123_5	1469245.JFBG01000056_gene2448	2.472e-63	229.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,1RZTV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_1219796_2	1123320.KB889730_gene5937	1.41e-22	113.0	2CH8M@1|root,348V3@2|Bacteria,2GTQ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1219796_0	298655.KI912266_gene1541	1.474e-206	651.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4EUFB@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GDHHQS3_k127_1219796_1	1125863.JAFN01000001_gene917	1.023e-22	109.0	COG1082@1|root,COG1082@2|Bacteria,1Q8EI@1224|Proteobacteria,430TI@68525|delta/epsilon subdivisions,2WVQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS3_k127_1231521_1	38727.Pavir.J02967.1.p	2.227e-07	61.0	KOG1940@1|root,KOG1940@2759|Eukaryota,37INM@33090|Viridiplantae,3G8ZR@35493|Streptophyta,3KRHQ@4447|Liliopsida,3IG8Z@38820|Poales	35493|Streptophyta	O	Hemerythrin HHE cation binding domain	-	-	-	ko:K16276	-	-	-	-	ko00000,ko04121	-	-	-	Hemerythrin,zf-CHY,zf-RING_2,zinc_ribbon_6
GDHHQS3_k127_1231521_0	255470.cbdbA392	1.822e-149	483.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,34CSJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GDHHQS3_k127_1232121_6	498761.HM1_0432	6.878e-13	70.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,24GK7@186801|Clostridia	186801|Clostridia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
GDHHQS3_k127_1232121_4	316274.Haur_0804	1.01e-77	270.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1232121_3	926550.CLDAP_00850	9.338e-83	289.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS
GDHHQS3_k127_1232121_0	402777.KB235904_gene4257	7.466e-117	385.0	COG0226@1|root,COG0226@2|Bacteria,1FZZ0@1117|Cyanobacteria,1H7JB@1150|Oscillatoriales	1117|Cyanobacteria	P	Phosphate ABC transporter substrate-binding protein, PhoT family	sphX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
GDHHQS3_k127_1232121_1	309801.trd_1831	6.554e-102	346.0	COG0573@1|root,COG0573@2|Bacteria,2G6CV@200795|Chloroflexi,27YPC@189775|Thermomicrobia	189775|Thermomicrobia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_1232121_2	986075.CathTA2_1846	1.18e-100	338.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli	91061|Bacilli	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_1232121_5	926550.CLDAP_00810	1.764e-42	163.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_1241193_5	1382315.JPOI01000001_gene1587	5.225e-18	90.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1WFIA@129337|Geobacillus	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS3_k127_1241193_3	1382356.JQMP01000003_gene2461	9.443e-57	213.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
GDHHQS3_k127_1241193_0	595460.RRSWK_04246	1.076e-197	641.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
GDHHQS3_k127_1241193_1	243164.DET0585	1.443e-116	397.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi,34CSC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS3_k127_1241193_4	243231.GSU0095	3.205e-23	108.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43VA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS3_k127_1241193_2	635013.TherJR_0070	2.531e-79	278.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,2612W@186807|Peptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
GDHHQS3_k127_1253302_2	485913.Krac_9564	6.604e-41	155.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
GDHHQS3_k127_1253302_0	95619.PM1_0203270	8.189e-287	896.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_1253302_1	1246995.AFR_42580	3.494e-51	185.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4DCYH@85008|Micromonosporales	201174|Actinobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_1256477_3	1007105.PT7_1606	7.865e-05	48.0	28YMR@1|root,2ZKFD@2|Bacteria,1P5YU@1224|Proteobacteria,2W62S@28216|Betaproteobacteria,3T4VF@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1256477_0	398525.KB900701_gene6584	1.704e-48	179.0	COG5517@1|root,COG5517@2|Bacteria,1RDWV@1224|Proteobacteria,2U2PR@28211|Alphaproteobacteria,3JXXH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Ring hydroxylating beta subunit	-	-	1.14.12.18	ko:K15750	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00543	R05261,R05262,R05263,R05264	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ring_hydroxyl_B
GDHHQS3_k127_1256477_1	493475.GARC_3010	2.505e-34	141.0	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria,1SNQ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_1256477_2	1121396.KB892935_gene3861	2.257e-32	135.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1300553_1	247633.GP2143_06105	6.545e-12	70.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1J694@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
GDHHQS3_k127_1300553_0	1231391.AMZF01000094_gene113	1.649e-158	518.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria	1224|Proteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GDHHQS3_k127_1319368_2	1040986.ATYO01000031_gene3157	8.72e-54	193.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,43J44@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GDHHQS3_k127_1319368_0	545694.TREPR_2877	4.548e-98	327.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_1319368_1	671143.DAMO_3032	1.57e-92	310.0	COG0861@1|root,COG0861@2|Bacteria,2NQFQ@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
GDHHQS3_k127_1319368_3	1227457.C451_02834	1.35e-14	79.0	arCOG07810@1|root,arCOG07810@2157|Archaea,2Y2GK@28890|Euryarchaeota,23ZFA@183963|Halobacteria	183963|Halobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_1322592_4	1173020.Cha6605_0902	2.222e-19	99.0	COG4645@1|root,COG4645@2|Bacteria,1GCIB@1117|Cyanobacteria	1117|Cyanobacteria	S	OpgC protein	-	-	-	-	-	-	-	-	-	-	-	-	OpgC_C
GDHHQS3_k127_1322592_0	713587.THITH_07725	8.54e-145	476.0	COG3379@1|root,COG3379@2|Bacteria,1PWC6@1224|Proteobacteria,1TKB0@1236|Gammaproteobacteria,1X1DI@135613|Chromatiales	135613|Chromatiales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_1322592_3	1183438.GKIL_2393	4.306e-49	188.0	COG1216@1|root,COG1216@2|Bacteria,1G346@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_1322592_1	251221.35214984	3.194e-115	379.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS3_k127_1322592_2	1123242.JH636434_gene5621	1.305e-81	276.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
GDHHQS3_k127_1322592_5	1463934.JOCF01000118_gene4108	3.06e-12	72.0	COG0491@1|root,COG0491@2|Bacteria,2GKBA@201174|Actinobacteria	201174|Actinobacteria	S	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13,Lactamase_B
GDHHQS3_k127_1322592_6	1120934.KB894408_gene4778	2.445e-09	67.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4E4IM@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GDHHQS3_k127_1344914_0	699218.HMPREF0889_1053	1.664e-18	98.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS3_k127_1344914_1	439235.Dalk_0482	0.0002115	53.0	COG1018@1|root,COG4447@1|root,COG1018@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
GDHHQS3_k127_1349256_2	1283287.KB822577_gene3388	4.898e-69	241.0	COG2128@1|root,COG2128@2|Bacteria,2IBNX@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS3_k127_1349256_3	1121937.AUHJ01000001_gene749	2.971e-49	192.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,1T3J3@1236|Gammaproteobacteria,469A4@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1349256_0	1183438.GKIL_1904	5.228e-79	279.0	COG0745@1|root,COG0745@2|Bacteria,1G16W@1117|Cyanobacteria	1117|Cyanobacteria	K	Two component transcriptional regulator, Winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1349256_1	1183438.GKIL_1905	1.5e-76	279.0	COG5002@1|root,COG5002@2|Bacteria,1GPX6@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_1349256_4	1150398.JIBJ01000011_gene2251	9.822e-38	154.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1364357_2	552811.Dehly_0228	1.582e-81	284.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	200795|Chloroflexi	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GDHHQS3_k127_1364357_3	309799.DICTH_0766	1.416e-21	106.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.12.1.3,1.6.5.3	ko:K00334,ko:K18330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07215	2Fe-2S_thioredx
GDHHQS3_k127_1364357_0	105422.BBPM01000001_gene4828	2.146e-198	637.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,2NF2Z@228398|Streptacidiphilus	201174|Actinobacteria	E	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS3_k127_1364357_4	644966.Tmar_2170	1.657e-21	100.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WDGS@538999|Clostridiales incertae sedis	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
GDHHQS3_k127_1364357_1	552811.Dehly_0841	5.343e-103	354.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi,34D3B@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_13917_0	479434.Sthe_1558	3.711e-75	264.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,27XHJ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS3_k127_13917_3	383372.Rcas_3713	4.197e-25	110.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,375V0@32061|Chloroflexia	32061|Chloroflexia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS3_k127_13917_2	525904.Tter_1410	1.92e-59	220.0	COG1559@1|root,COG1559@2|Bacteria,2NP75@2323|unclassified Bacteria	2|Bacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS3_k127_13917_1	264732.Moth_1558	1.34e-65	235.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,42ES9@68295|Thermoanaerobacterales	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
GDHHQS3_k127_1398254_0	926569.ANT_13120	4.968e-85	295.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_1398484_0	314230.DSM3645_20632	2.498e-103	351.0	COG1201@1|root,COG1201@2|Bacteria,2IX0G@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS3_k127_1398484_3	1121370.AQUY01000001_gene164	0.0006094	51.0	COG2265@1|root,COG2265@2|Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_1398484_2	234267.Acid_1665	1.058e-58	217.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
GDHHQS3_k127_1402421_1	671143.DAMO_2385	5.072e-99	334.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS3_k127_1402421_3	1218173.BALCAV_0221590	7.767e-27	118.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,1ZEGI@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
GDHHQS3_k127_1402421_0	243164.DET1372	2.472e-103	346.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi,34CMM@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_1402421_2	189426.PODO_11985	4.683e-49	183.0	2AHFH@1|root,317ST@2|Bacteria,1V7CC@1239|Firmicutes,4I891@91061|Bacilli,26ZAV@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
GDHHQS3_k127_1409519_0	107635.AZUO01000001_gene3356	8.452e-143	479.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS3_k127_1409519_1	358396.C445_20845	2.282e-24	105.0	COG4274@1|root,arCOG01119@2157|Archaea,2Y0W5@28890|Euryarchaeota,23XG3@183963|Halobacteria	183963|Halobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
GDHHQS3_k127_143656_1	639030.JHVA01000001_gene1656	1.397e-10	64.0	COG1555@1|root,COG1555@2|Bacteria,3Y8EF@57723|Acidobacteria,2JNFN@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
GDHHQS3_k127_143656_0	926550.CLDAP_18870	1.096e-112	393.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS3_k127_1486742_0	552811.Dehly_1402	4.195e-80	278.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,34CMZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_1486742_1	357808.RoseRS_0557	5.892e-59	224.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi,375GV@32061|Chloroflexia	32061|Chloroflexia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
GDHHQS3_k127_1486742_2	1121468.AUBR01000001_gene540	5.333e-53	197.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,42GFH@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_1496009_0	483219.LILAB_36410	8.948e-23	102.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJ9@29|Myxococcales	28221|Deltaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_1496009_1	204669.Acid345_1569	3.753e-17	88.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_1496009_2	191610.CATYP_02340	5.687e-06	57.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,22NC6@1653|Corynebacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GDHHQS3_k127_151101_3	5022.CBY01813	1.003e-06	53.0	COG1546@1|root,2S20M@2759|Eukaryota,3A3UF@33154|Opisthokonta,3P3E5@4751|Fungi,3QVP9@4890|Ascomycota,201VQ@147541|Dothideomycetes,4KJPM@92860|Pleosporales	4751|Fungi	S	Competence-damaged protein	-	-	-	-	-	-	-	-	-	-	-	-	CinA
GDHHQS3_k127_151101_1	935548.KI912159_gene2811	1.268e-74	265.0	2EHHS@1|root,33B9Q@2|Bacteria,1NGK1@1224|Proteobacteria,2UMZT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_151101_0	426117.M446_0613	7.588e-99	336.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JT1V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_151101_2	552811.Dehly_0898	4.136e-22	98.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	MA20_27970	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_1555039_0	404380.Gbem_2646	3.415e-105	360.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
GDHHQS3_k127_1555039_1	1246474.ANBE01000006_gene663	3.194e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_1555039_2	1122604.JONR01000001_gene1773	1.793e-08	58.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1SM1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1565215_0	1125863.JAFN01000001_gene2311	3.421e-63	230.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS3_k127_1565215_1	930169.B5T_03305	5.266e-63	228.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XH9S@135619|Oceanospirillales	135619|Oceanospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_1565215_2	1205680.CAKO01000029_gene5023	5.955e-17	82.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,2JPTF@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_159474_0	926550.CLDAP_29280	4.945e-83	286.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_159474_3	555079.Toce_1014	3.906e-29	124.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,42GTZ@68295|Thermoanaerobacterales	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS3_k127_159474_1	1382304.JNIL01000001_gene3204	3.961e-80	273.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GDHHQS3_k127_159474_2	243164.DET1425	2.904e-79	280.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,34CK7@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_159474_4	1220583.GOACH_14_00210	0.0001892	51.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria,4GECK@85026|Gordoniaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_1630992_2	1246448.ANAZ01000007_gene2173	1.749e-59	212.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_1630992_5	1382356.JQMP01000003_gene1440	6.027e-40	160.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_1630992_3	479434.Sthe_1897	8.897e-55	204.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS3_k127_1630992_1	717605.Theco_0031	1.768e-70	250.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,4HAU2@91061|Bacilli,26RB5@186822|Paenibacillaceae	91061|Bacilli	IQ	reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_1630992_4	525904.Tter_1678	8.086e-41	164.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS3_k127_1630992_0	138119.DSY1012	0.0	1149.0	COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,24DM7@186801|Clostridia,260RF@186807|Peptococcaceae	186801|Clostridia	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
GDHHQS3_k127_1630992_6	1380347.JNII01000006_gene1111	9.216e-40	153.0	COG1309@1|root,COG1309@2|Bacteria,2GTS6@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_1636218_0	639283.Snov_1607	4.166e-134	444.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,3EZS5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GDHHQS3_k127_1649113_3	1541065.JRFE01000025_gene2003	1.263e-25	108.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria,3VIEN@52604|Pleurocapsales	1117|Cyanobacteria	JM	COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_1649113_4	266117.Rxyl_2570	1.793e-21	104.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS3_k127_1649113_5	1499967.BAYZ01000115_gene2916	1.675e-12	71.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GDHHQS3_k127_1649113_2	326427.Cagg_3848	3.521e-40	156.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS3_k127_1649113_0	264732.Moth_0818	1.461e-88	305.0	COG0530@1|root,COG0530@2|Bacteria,1UE3Y@1239|Firmicutes,25IY9@186801|Clostridia,42F30@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GDHHQS3_k127_1649113_1	479434.Sthe_1818	1.169e-56	211.0	COG2042@1|root,COG3376@2|Bacteria	2|Bacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
GDHHQS3_k127_1649113_6	1449076.JOOE01000002_gene1081	6.991e-05	54.0	COG1807@1|root,COG1807@2|Bacteria,1N5WU@1224|Proteobacteria,2TZ8U@28211|Alphaproteobacteria,2K2JP@204457|Sphingomonadales	204457|Sphingomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_1673873_0	1210884.HG799464_gene10982	4.111e-117	388.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
GDHHQS3_k127_1673873_6	742741.HMPREF9475_00185	2.465e-16	90.0	COG3608@1|root,COG3608@2|Bacteria,1VJ8A@1239|Firmicutes,24NHM@186801|Clostridia	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
GDHHQS3_k127_1673873_5	203124.Tery_2073	2.006e-17	87.0	COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_1673873_3	1216976.AX27061_5257	7.064e-58	214.0	COG1052@1|root,COG1052@2|Bacteria,1QZ4K@1224|Proteobacteria	1224|Proteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_1673873_1	1224164.B843_01215	2.524e-94	326.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,22K8Y@1653|Corynebacteriaceae	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	scoB	-	2.8.3.5	ko:K01027,ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS3_k127_1673873_4	479434.Sthe_0539	6.82e-41	156.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydratas,OB_aCoA_assoc
GDHHQS3_k127_1673873_2	479434.Sthe_0538	9.508e-88	294.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_1679951_0	1123487.KB892865_gene1503	2.205e-66	239.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_173524_0	1382356.JQMP01000003_gene1423	2.522e-42	171.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS3_k127_173524_1	700508.D174_10780	6.042e-27	115.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,232UD@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
GDHHQS3_k127_1766528_7	266779.Meso_1055	0.000842	46.0	COG0697@1|root,COG2510@1|root,COG0697@2|Bacteria,COG2510@2|Bacteria,1Q6VT@1224|Proteobacteria,2USD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_1766528_4	1254432.SCE1572_30125	1.168e-28	120.0	COG3437@1|root,COG3829@1|root,COG3852@1|root,COG4251@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X7X2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GDHHQS3_k127_1766528_6	1298858.AUEL01000007_gene2375	0.0004084	48.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,43JCM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1766528_1	1123023.JIAI01000018_gene2512	1.626e-73	259.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.16	ko:K05713	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R04376,R06788	RC01140,RC01364	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
GDHHQS3_k127_1766528_3	644966.Tmar_1595	8.964e-40	159.0	COG1622@1|root,COG1622@2|Bacteria,1TRC3@1239|Firmicutes,25348@186801|Clostridia	186801|Clostridia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GDHHQS3_k127_1766528_0	1283299.AUKG01000001_gene3221	1.144e-165	544.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CS3H@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
GDHHQS3_k127_1766528_2	926550.CLDAP_10590	1.825e-53	193.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS3_k127_1770588_0	479434.Sthe_0985	1.702e-158	516.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_177408_1	1095767.CAHD01000213_gene574	7.411e-06	49.0	COG3832@1|root,COG3832@2|Bacteria,2IBWM@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_177408_0	311424.DhcVS_381	2.143e-158	527.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,34CZW@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
GDHHQS3_k127_1774294_3	1382306.JNIM01000001_gene294	4.8e-15	78.0	29684@1|root,2ZTI4@2|Bacteria,2G9NR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1774294_0	309801.trd_0107	7.219e-184	581.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,27XJP@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1774294_1	65672.G4TB02	1.195e-43	173.0	COG0134@1|root,COG0135@1|root,COG0512@1|root,KOG0026@2759|Eukaryota,KOG4201@2759|Eukaryota,KOG4202@2759|Eukaryota,38FIR@33154|Opisthokonta,3NU49@4751|Fungi,3UZN9@5204|Basidiomycota,224SV@155619|Agaricomycetes,3H2VM@355688|Agaricomycetes incertae sedis	4751|Fungi	E	Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities	TRP3	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.1.48,4.1.3.27,5.3.1.24	ko:K01656,ko:K13501	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R03508,R03509	RC00010,RC00944,RC00945,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,IGPS,PRAI
GDHHQS3_k127_1774294_2	264732.Moth_1339	6.685e-29	119.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,42EQ2@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS3_k127_1774830_1	1340493.JNIF01000002_gene1262	8.277e-29	128.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_1774830_2	497964.CfE428DRAFT_0093	2.334e-24	117.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_1774830_0	1121272.KB903290_gene4739	6.073e-52	190.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1776915_2	644283.Micau_2170	0.0003727	51.0	COG3764@1|root,COG3764@2|Bacteria,2IFPY@201174|Actinobacteria,4DCW1@85008|Micromonosporales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_1776915_1	309801.trd_A0640	8.596e-27	119.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_1776915_0	309799.DICTH_0173	4.232e-95	318.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_1806713_1	1121468.AUBR01000008_gene2055	2.282e-57	203.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
GDHHQS3_k127_1806713_2	1128421.JAGA01000002_gene1167	1.186e-36	145.0	COG0801@1|root,COG0801@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
GDHHQS3_k127_1806713_3	304371.MCP_0278	2.562e-22	97.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
GDHHQS3_k127_1806713_0	485913.Krac_12038	2.696e-287	906.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_1857520_0	351160.RCIX1517	2.499e-223	717.0	COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_1857520_3	485913.Krac_8885	2.522e-30	126.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS3_k127_1857520_5	748280.NH8B_0245	4.251e-07	58.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KPI0@206351|Neisseriales	206351|Neisseriales	P	Psort location CytoplasmicMembrane, score	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_1857520_1	1162668.LFE_2373	8.978e-103	353.0	COG1892@1|root,COG1892@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppcA	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase_2
GDHHQS3_k127_1857520_6	693977.Deipr_1662	1.509e-06	54.0	COG1826@1|root,COG1826@2|Bacteria,1WKBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_1857520_4	926550.CLDAP_39560	6.567e-20	94.0	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS3_k127_1857520_2	311424.DhcVS_61	1.571e-86	292.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,34CQ5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	cysteinyl-tRNA aminoacylation	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS3_k127_1865734_1	926550.CLDAP_08170	4.775e-136	441.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_1865734_0	255470.cbdbA577	2.866e-226	732.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,34CJG@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS3_k127_1865734_2	309801.trd_0180	1.228e-71	247.0	COG0118@1|root,COG0118@2|Bacteria,2G6FD@200795|Chloroflexi,27Y6F@189775|Thermomicrobia	189775|Thermomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS3_k127_1877780_0	316274.Haur_3265	2.595e-52	205.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS3_k127_1877780_1	479434.Sthe_2506	1.525e-46	181.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_189629_2	1382356.JQMP01000003_gene1444	0.0007	43.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,27Y4E@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS3_k127_189629_1	648996.Theam_0944	8.962e-41	166.0	COG0616@1|root,COG0616@2|Bacteria,2G409@200783|Aquificae	200783|Aquificae	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS3_k127_189629_0	525904.Tter_0811	1.193e-297	935.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS3_k127_1900371_0	234267.Acid_5606	3.387e-111	374.0	COG1215@1|root,COG1215@2|Bacteria,3Y6KA@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,T2SSE_N
GDHHQS3_k127_1901356_0	1123242.JH636434_gene5099	3.417e-71	243.0	COG1060@1|root,COG1060@2|Bacteria,2IX1I@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_1901356_2	1210884.HG799469_gene14112	0.0001077	50.0	2E5C9@1|root,336H9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1901356_1	314230.DSM3645_13550	4.587e-52	199.0	COG2165@1|root,COG2165@2|Bacteria,2IZZB@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
GDHHQS3_k127_1901576_0	1089550.ATTH01000001_gene985	0.0002344	52.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1FIRV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
GDHHQS3_k127_1909937_1	1056816.JAFQ01000004_gene5452	8.861e-113	373.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria,4G8U3@85025|Nocardiaceae	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
GDHHQS3_k127_1909937_0	266117.Rxyl_3202	0.0	1085.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_1909937_3	485913.Krac_7491	1.974e-13	80.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GDHHQS3_k127_1909937_2	710686.Mycsm_00595	6.897e-60	215.0	COG4280@1|root,COG4280@2|Bacteria,2GN58@201174|Actinobacteria,236RB@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
GDHHQS3_k127_1927020_0	525904.Tter_2353	9.761e-90	323.0	COG1529@1|root,COG1529@2|Bacteria,2NPHP@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4,1.3.99.16	ko:K00256,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_1927020_1	525904.Tter_2354	3.112e-46	171.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	iorA	-	1.2.5.3,1.3.99.16	ko:K00256,ko:K03518,ko:K07302,ko:K07303,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_1927020_3	869210.Marky_2134	1.1e-11	71.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GDHHQS3_k127_1927020_2	331869.BAL199_08898	2.026e-16	87.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1933481_0	366602.Caul_3941	7.472e-220	696.0	COG1629@1|root,COG1629@2|Bacteria,1QUTW@1224|Proteobacteria,2TW7F@28211|Alphaproteobacteria,2KFR5@204458|Caulobacterales	204458|Caulobacterales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_1933481_1	1121015.N789_02220	2.648e-196	621.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1X3GK@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_8
GDHHQS3_k127_1973519_1	460265.Mnod_4105	2.216e-10	71.0	2EN65@1|root,33FU2@2|Bacteria,1NF56@1224|Proteobacteria,2UHK8@28211|Alphaproteobacteria,1JYM4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1984694_0	941449.dsx2_1459	4.858e-61	222.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2M8AB@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	pfam abc	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
GDHHQS3_k127_1984694_1	941449.dsx2_1460	5.808e-38	153.0	COG1682@1|root,COG1682@2|Bacteria,1QXTH@1224|Proteobacteria,42XN1@68525|delta/epsilon subdivisions,2WSPR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_1984694_3	1380390.JIAT01000010_gene4922	4.481e-20	104.0	COG2199@1|root,COG3706@2|Bacteria,2HFS4@201174|Actinobacteria,4CRDM@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_1984694_2	1408224.SAMCCGM7_c6619	2.104e-32	143.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,4BAPG@82115|Rhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Guanylate_cyc,Hydrolase_4,Trans_reg_C
GDHHQS3_k127_1985625_0	42256.RradSPS_1222	2.28e-49	185.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_1985625_1	1379698.RBG1_1C00001G0843	2.408e-22	106.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_1985625_2	1487923.DP73_20430	1.551e-11	68.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,261I7@186807|Peptococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_1995025_0	1501230.ET33_02970	5.349e-261	824.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GDHHQS3_k127_2050143_2	649831.L083_4957	8.036e-45	187.0	COG1835@1|root,COG1835@2|Bacteria,2GKM1@201174|Actinobacteria,4D9IW@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS3_k127_2050143_3	1033730.CAHG01000016_gene385	1.986e-26	127.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4DP8S@85009|Propionibacteriales	201174|Actinobacteria	V	Beta-lactamase	blaA2	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
GDHHQS3_k127_2050143_1	1122915.AUGY01000118_gene6539	3.68e-91	312.0	COG1063@1|root,COG1063@2|Bacteria,1UWR7@1239|Firmicutes,4I2SG@91061|Bacilli,272W9@186822|Paenibacillaceae	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_2050143_0	1134413.ANNK01000089_gene360	1.383e-123	409.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_2056317_2	1382356.JQMP01000001_gene1055	1.961e-18	92.0	28HQ3@1|root,2Z7XW@2|Bacteria,2G9Q4@200795|Chloroflexi,27XYJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
GDHHQS3_k127_2056317_3	864702.OsccyDRAFT_1898	2.335e-17	83.0	COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria,1HBR9@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GDHHQS3_k127_2056317_1	309801.trd_1301	5.498e-33	130.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi,27YJ2@189775|Thermomicrobia	189775|Thermomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS3_k127_2056317_0	309801.trd_1300	3.321e-183	580.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS3_k127_2060915_2	357804.Ping_1764	2.93e-06	54.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2060915_0	338969.Rfer_3112	3.184e-113	373.0	COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria,4AD6Z@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstP	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3
GDHHQS3_k127_2060915_1	1207063.P24_01150	2.868e-44	164.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2V8XE@28211|Alphaproteobacteria,2JXR9@204441|Rhodospirillales	204441|Rhodospirillales	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2062094_0	1223521.BBJX01000021_gene2988	8.432e-14	80.0	COG5661@1|root,COG5661@2|Bacteria,1N5NW@1224|Proteobacteria,2VUAH@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Bacterial protein of unknown function (DUF922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
GDHHQS3_k127_2073996_0	1408164.MOLA814_00047	9.042e-115	376.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KPQ3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS3_k127_2073996_1	555779.Dthio_PD1478	1.705e-89	309.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS3_k127_211998_1	552811.Dehly_1588	8.301e-61	218.0	COG2159@1|root,COG2159@2|Bacteria,2G6CW@200795|Chloroflexi,34CYX@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS3_k127_211998_3	552811.Dehly_1587	1.856e-24	115.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,34D41@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS3_k127_211998_2	635013.TherJR_0229	1.712e-35	141.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,261HN@186807|Peptococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_211998_0	243164.DET0578	1.538e-173	557.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi,34CKJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	lysyl-tRNA aminoacylation	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_2127419_4	289376.THEYE_A0363	5.169e-27	117.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS3_k127_2127419_2	292459.STH1996	3.636e-29	122.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia	186801|Clostridia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_2127419_6	436229.JOEH01000030_gene4771	3.791e-19	99.0	COG0500@1|root,COG2226@2|Bacteria,2HER4@201174|Actinobacteria,2NK2Q@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_2127419_0	1231391.AMZF01000063_gene1104	2.992e-117	396.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria	1224|Proteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GDHHQS3_k127_2127419_3	1317122.ATO12_14875	3.904e-29	123.0	2CJSZ@1|root,32XRW@2|Bacteria,4P6KZ@976|Bacteroidetes,1IHWR@117743|Flavobacteriia,2YK2R@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2127419_5	867903.ThesuDRAFT_02068	1.2e-26	116.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
GDHHQS3_k127_2127419_7	1386089.N865_06400	7.998e-16	85.0	2CK59@1|root,32RQ2@2|Bacteria,2IFCF@201174|Actinobacteria,4FI6Q@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_2127419_1	1340493.JNIF01000003_gene2232	7.775e-59	211.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_2132938_0	1157708.KB907462_gene897	1.809e-190	601.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
GDHHQS3_k127_2142270_3	326427.Cagg_2934	3.174e-29	118.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,375RY@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GDHHQS3_k127_2142270_2	383372.Rcas_1948	8.907e-75	261.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,374VI@32061|Chloroflexia	32061|Chloroflexia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS3_k127_2142270_4	1122962.AULH01000001_gene1660	8.85e-12	72.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,2U9I3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
GDHHQS3_k127_2142270_1	1123072.AUDH01000025_gene345	1.497e-86	295.0	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria,2JV21@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_216400_2	1254432.SCE1572_13540	3.359e-107	352.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GDHHQS3_k127_216400_3	317936.Nos7107_0503	5.785e-17	90.0	2CG06@1|root,33MVM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_216400_0	867845.KI911784_gene3666	1.546e-143	471.0	COG1052@1|root,COG1052@2|Bacteria,2GA73@200795|Chloroflexi,374WJ@32061|Chloroflexia	32061|Chloroflexia	CH	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS3_k127_216400_1	255470.cbdbA581	2.223e-113	377.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi,34CWR@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_2215084_1	479434.Sthe_0385	8.283e-69	241.0	COG0322@1|root,COG0758@1|root,COG0322@2|Bacteria,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi,27XEI@189775|Thermomicrobia	189775|Thermomicrobia	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS3_k127_2215084_0	1382306.JNIM01000001_gene2574	3.913e-73	263.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_2215084_3	1198449.ACAM_0762	3.151e-35	150.0	COG1208@1|root,arCOG00666@2157|Archaea,2XQ1Z@28889|Crenarchaeota	28889|Crenarchaeota	M	nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GDHHQS3_k127_2215084_5	1259795.ARJK01000002_gene319	0.0004135	46.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,42G9C@68295|Thermoanaerobacterales	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_2215084_2	1128421.JAGA01000002_gene55	8.059e-51	190.0	COG2227@1|root,COG2227@2|Bacteria,2NRDG@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_2215084_4	1382359.JIAL01000001_gene2346	5.824e-17	83.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GDHHQS3_k127_2218686_0	1382356.JQMP01000001_gene835	1.857e-86	290.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_2218686_1	926550.CLDAP_05830	9.766e-05	53.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GDHHQS3_k127_2244282_2	1121124.JNIX01000008_gene2405	3.077e-46	171.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2KFNP@204458|Caulobacterales	204458|Caulobacterales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GDHHQS3_k127_2244282_4	215803.DB30_7646	1.406e-38	149.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1AT@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_2244282_1	221359.RS9916_37047	1.434e-79	279.0	COG0404@1|root,COG0404@2|Bacteria,1G0GR@1117|Cyanobacteria,1GYU4@1129|Synechococcus	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_2244282_0	118163.Ple7327_1920	9.114e-267	841.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,3VJCM@52604|Pleurocapsales	1117|Cyanobacteria	E	WD40-like Beta Propeller Repeat	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_2244282_3	1128421.JAGA01000003_gene3143	2.844e-42	173.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Response_reg
GDHHQS3_k127_2259939_1	1107311.Q767_15055	0.0001335	49.0	COG3391@1|root,COG3391@2|Bacteria,4PPH2@976|Bacteroidetes,1IKMV@117743|Flavobacteriia,2NUGB@237|Flavobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR
GDHHQS3_k127_2259939_0	267748.MMOB6010	1.741e-58	213.0	COG1004@1|root,COG1004@2|Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_2263396_0	926569.ANT_22440	1.184e-74	266.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
GDHHQS3_k127_2263396_3	926569.ANT_22430	3.725e-27	113.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS3_k127_2263396_1	926569.ANT_22420	1.422e-62	218.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS3_k127_2263396_2	926569.ANT_22410	2.826e-30	122.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS3_k127_2263396_4	469383.Cwoe_1915	1.055e-08	57.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
GDHHQS3_k127_226981_0	255470.cbdbA281	7.991e-89	301.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,34CIZ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS3_k127_226981_4	1121926.AXWO01000003_gene848	3.342e-27	117.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4EYNZ@85014|Glycomycetales	201174|Actinobacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS3_k127_226981_2	243231.GSU2705	1.028e-50	184.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria,43UQA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
GDHHQS3_k127_226981_1	717605.Theco_2126	4.558e-88	296.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS3_k127_226981_3	370438.PTH_1718	2.251e-37	144.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS3_k127_2272871_2	649638.Trad_1105	4.88e-42	172.0	COG0419@1|root,COG0419@2|Bacteria,1WJ38@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
GDHHQS3_k127_2272871_1	582515.KR51_00020230	2.09e-61	233.0	COG0420@1|root,COG0420@2|Bacteria,1G0JQ@1117|Cyanobacteria	1117|Cyanobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
GDHHQS3_k127_2272871_0	1122182.KB903837_gene3715	6.201e-159	519.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_2272871_3	99598.Cal7507_1758	2.812e-31	135.0	COG2380@1|root,COG2380@2|Bacteria,1GDAS@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_229172_2	1128421.JAGA01000003_gene2743	7.818e-81	280.0	COG1169@1|root,COG1169@2|Bacteria,2NQZP@2323|unclassified Bacteria	2|Bacteria	HQ	chorismate binding enzyme	menF	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	5.4.4.2	ko:K01851,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30830	Chorismate_bind
GDHHQS3_k127_229172_0	479434.Sthe_3024	1.233e-185	604.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
GDHHQS3_k127_229172_3	479434.Sthe_3023	4.927e-80	280.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GDHHQS3_k127_229172_1	986075.CathTA2_0633	5.352e-149	476.0	COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli	91061|Bacilli	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_229172_4	479434.Sthe_3017	7.39e-62	227.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,27YF9@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_2292286_3	1041147.AUFB01000003_gene3650	2.117e-10	61.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
GDHHQS3_k127_2292286_1	316056.RPC_4057	2.348e-66	238.0	COG3335@1|root,COG3335@2|Bacteria,1RDBN@1224|Proteobacteria,2VFA9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposable element conserved	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS3_k127_2292286_2	1429916.X566_00575	2.249e-50	184.0	COG3415@1|root,COG3415@2|Bacteria,1RDMQ@1224|Proteobacteria,2U7PU@28211|Alphaproteobacteria,3K38Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
GDHHQS3_k127_2292286_0	190650.CC_2798	1.111e-177	560.0	COG2141@1|root,COG2141@2|Bacteria,1MXZH@1224|Proteobacteria,2TQJH@28211|Alphaproteobacteria,2KI90@204458|Caulobacterales	204458|Caulobacterales	C	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate	rutA	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.14.99.46	ko:K09018	ko00240,ko01100,map00240,map01100	-	R09936	RC02732	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
GDHHQS3_k127_2297436_3	1440053.JOEI01000013_gene4917	1.179e-11	68.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_2297436_2	573065.Astex_2063	7.701e-22	100.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD,Cupin_2
GDHHQS3_k127_2297436_1	290399.Arth_2029	9.512e-36	144.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,1WANS@1268|Micrococcaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
GDHHQS3_k127_2297436_0	234267.Acid_5241	1.827e-40	158.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2369278_11	1330700.JQNC01000003_gene1512	6.106e-11	71.0	COG1173@1|root,COG1173@2|Bacteria,1WI67@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_2369278_1	311424.DhcVS_931	1.45e-103	346.0	COG0601@1|root,COG0601@2|Bacteria,2G9WT@200795|Chloroflexi,34DMG@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
GDHHQS3_k127_2369278_0	311424.DhcVS_932	1.726e-124	420.0	COG4166@1|root,COG4166@2|Bacteria,2G81T@200795|Chloroflexi,34DKF@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS3_k127_2369278_10	1205910.B005_5504	7.628e-13	77.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4EJI2@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	sufE	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_2369278_9	1040989.AWZU01000109_gene140	6.907e-18	86.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,2UF7G@28211|Alphaproteobacteria,3JZH1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710,ko:K14578	ko00360,ko00624,ko00626,ko00627,ko00633,ko00642,ko01100,ko01120,ko01220,map00360,map00624,map00626,map00627,map00633,map00642,map01100,map01120,map01220	M00534,M00545,M00638	R02968,R05422,R05423,R05424,R05425,R05426,R05427,R06782,R06783,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R09159,R09233	RC00091,RC00098,RC00157,RC00274,RC00275,RC00490,RC01376,RC01377,RC01801	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_2369278_8	1245475.ANAE01000141_gene4574	1.394e-21	97.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4EJI2@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	sufE	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_2369278_2	1206731.BAGB01000164_gene4285	1.518e-55	215.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_2369278_3	1206731.BAGB01000164_gene4286	1.239e-37	153.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_2369278_6	1206731.BAGB01000164_gene4283	1.697e-32	136.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS3_k127_2369278_5	1206731.BAGB01000164_gene4283	4.759e-33	139.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS3_k127_2369278_4	1206731.BAGB01000164_gene4283	6.585e-37	145.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS3_k127_2414748_6	326424.FRAAL1158	3.175e-05	51.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_2414748_3	926550.CLDAP_05380	2.34e-24	109.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_2414748_2	926550.CLDAP_05380	8.287e-27	118.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_2414748_0	525904.Tter_1053	4.404e-54	198.0	COG0586@1|root,COG0586@2|Bacteria,2NPJ6@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_2414748_5	1552758.NC00_17030	2.944e-09	69.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PYUK@1224|Proteobacteria,1S0VV@1236|Gammaproteobacteria,1X5W9@135614|Xanthomonadales	135614|Xanthomonadales	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
GDHHQS3_k127_2414748_4	357808.RoseRS_4493	2.064e-23	114.0	COG0741@1|root,COG0741@2|Bacteria	357808.RoseRS_4493|-	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2414748_1	1382306.JNIM01000001_gene3787	2.813e-27	117.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2438196_6	469383.Cwoe_5413	1.662e-07	60.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRNG@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_2438196_4	1120792.JAFV01000001_gene631	3.706e-24	105.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,36YEQ@31993|Methylocystaceae	28211|Alphaproteobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_2438196_2	1211777.BN77_p10571	1.618e-75	261.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,4BA1X@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_2438196_0	926550.CLDAP_39770	1.277e-101	341.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_2438196_3	383372.Rcas_3055	1.325e-46	183.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi,375EP@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_2438196_1	316274.Haur_3900	1.557e-80	278.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2438196_5	243365.CV_4309	6.223e-20	93.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,2KQD9@206351|Neisseriales	206351|Neisseriales	E	aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS3_k127_2468047_1	243164.DET0994	2.578e-64	224.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,34CRP@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
GDHHQS3_k127_2468047_2	309801.trd_0681	1.438e-54	195.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi,27Y72@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS3_k127_2468047_0	255470.cbdbA956	2.293e-86	291.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi,34CNG@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS3_k127_2468047_3	1120971.AUCA01000013_gene2594	5.246e-31	128.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,278CE@186823|Alicyclobacillaceae	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GDHHQS3_k127_2468047_4	644966.Tmar_2304	2.415e-07	57.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WD9N@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS3_k127_2479751_2	1128421.JAGA01000002_gene1259	3.832e-18	90.0	COG1525@1|root,COG1680@1|root,COG1525@2|Bacteria,COG1680@2|Bacteria,2NQ3M@2323|unclassified Bacteria	2|Bacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1,3.4.16.4	ko:K01174,ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,Beta-lactamase,SNase
GDHHQS3_k127_2479751_1	697303.Thewi_0474	8.96e-19	96.0	2DRTD@1|root,32URM@2|Bacteria,1VB2V@1239|Firmicutes,24NVT@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
GDHHQS3_k127_2479751_0	1121405.dsmv_0645	1.48e-106	355.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2MHR8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS3_k127_2509832_0	1382306.JNIM01000001_gene1032	4.396e-88	310.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_2509832_2	1384057.CD33_13430	7.308e-29	134.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HF06@91061|Bacilli	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_2509832_1	357808.RoseRS_0783	3.892e-38	146.0	COG2346@1|root,COG2346@2|Bacteria,2G9T7@200795|Chloroflexi,377F9@32061|Chloroflexia	32061|Chloroflexia	S	PFAM globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS3_k127_2511703_1	867903.ThesuDRAFT_00300	2.97e-98	331.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WCG9@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS3_k127_2511703_0	926550.CLDAP_20060	1.1e-170	580.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS3_k127_2511703_3	243164.DET1025	4.135e-54	201.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi,34D6R@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS3_k127_2511703_2	324602.Caur_2015	6.866e-57	214.0	COG0617@1|root,COG0617@2|Bacteria,2G8YQ@200795|Chloroflexi,375MA@32061|Chloroflexia	32061|Chloroflexia	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
GDHHQS3_k127_2568742_1	868595.Desca_0116	1.075e-38	146.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,261SD@186807|Peptococcaceae	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS3_k127_2568742_0	1380394.JADL01000012_gene824	4.639e-59	217.0	COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria,2JWBN@204441|Rhodospirillales	204441|Rhodospirillales	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
GDHHQS3_k127_2568742_2	1210884.HG799462_gene8426	5.642e-38	147.0	COG1186@1|root,COG1186@2|Bacteria,2IZSY@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
GDHHQS3_k127_256929_2	500153.JOEK01000002_gene100	1.164e-08	57.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
GDHHQS3_k127_256929_0	1131462.DCF50_p2293	6.09e-105	357.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_256929_1	1449126.JQKL01000022_gene110	5.609e-98	328.0	COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,24AAH@186801|Clostridia	186801|Clostridia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_2572005_0	383372.Rcas_4390	6.161e-79	276.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GDHHQS3_k127_2572005_1	324602.Caur_2075	5.204e-34	138.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi,375MV@32061|Chloroflexia	32061|Chloroflexia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS3_k127_257708_1	357808.RoseRS_3858	1.87e-84	293.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
GDHHQS3_k127_257708_0	1382356.JQMP01000003_gene1444	2e-118	389.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,27Y4E@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS3_k127_2590797_0	324602.Caur_0620	1.788e-83	289.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS3_k127_2590797_1	338963.Pcar_2572	1.518e-44	170.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2WNGC@28221|Deltaproteobacteria,43SEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	nth	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
GDHHQS3_k127_2590797_2	675635.Psed_5543	3.739e-39	154.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria,4EBVH@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,SnoaL_2
GDHHQS3_k127_2590797_3	1120973.AQXL01000115_gene628	1.046e-26	115.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,4HHKH@91061|Bacilli,27A3N@186823|Alicyclobacillaceae	91061|Bacilli	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GDHHQS3_k127_2600078_0	311424.DhcVS_672	2.258e-234	745.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,34CNJ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_2631901_6	1283283.ATXA01000006_gene1854	1.573e-40	159.0	COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria	201174|Actinobacteria	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_2631901_0	525904.Tter_1871	3.437e-177	576.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS3_k127_2631901_7	479434.Sthe_2006	6.518e-35	139.0	COG0432@1|root,COG1304@1|root,COG0432@2|Bacteria,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
GDHHQS3_k127_2631901_9	479434.Sthe_1748	1.897e-20	100.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi,27YJ3@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2631901_4	4792.ETI34358	2.731e-66	239.0	COG0613@1|root,2QUA5@2759|Eukaryota,3QFBB@4776|Peronosporales	4776|Peronosporales	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GDHHQS3_k127_2631901_2	555079.Toce_1208	2.002e-82	283.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
GDHHQS3_k127_2631901_1	479434.Sthe_0703	3.347e-166	537.0	COG1418@1|root,COG1418@2|Bacteria,2G620@200795|Chloroflexi,27Y2Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS3_k127_2631901_5	1303518.CCALI_01951	1.885e-59	213.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GDHHQS3_k127_2631901_3	42256.RradSPS_0124	2.202e-73	258.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GDHHQS3_k127_2631901_8	1043493.BBLU01000014_gene1202	5.01e-31	127.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS3_k127_2631901_10	633149.Bresu_1547	6.355e-07	52.0	2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UF5V@28211|Alphaproteobacteria,2KIU5@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2671571_0	1321778.HMPREF1982_02228	4.153e-35	153.0	COG0577@1|root,COG0577@2|Bacteria,1TSP8@1239|Firmicutes,2481U@186801|Clostridia	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_2676599_10	469383.Cwoe_1578	5.18e-22	101.0	COG0627@1|root,COG0627@2|Bacteria,2HQW9@201174|Actinobacteria,4CSNZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS3_k127_2676599_7	886379.AEWI01000204_gene2379	1.423e-25	119.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia,3XM14@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS3_k127_2676599_9	479434.Sthe_2667	4.062e-24	113.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_2676599_8	1896.JOAU01000010_gene439	2.938e-25	114.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
GDHHQS3_k127_2676599_5	543526.Htur_2809	6.085e-50	185.0	COG1926@1|root,arCOG00041@2157|Archaea,2XWHP@28890|Euryarchaeota,23TDQ@183963|Halobacteria	183963|Halobacteria	F	phosphoribosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS3_k127_2676599_0	472759.Nhal_1884	1.449e-213	672.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WZYK@135613|Chromatiales	135613|Chromatiales	H	Belongs to the RtcB family	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GDHHQS3_k127_2676599_6	1123393.KB891316_gene1686	9.475e-48	176.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
GDHHQS3_k127_2676599_11	926550.CLDAP_28530	3.888e-09	67.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_2676599_12	863239.AFIZ01000035_gene2158	5.857e-09	58.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,22KEE@1653|Corynebacteriaceae	201174|Actinobacteria	P	cation transport ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_2676599_14	631454.N177_1761	3.884e-06	52.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,2U8SB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
GDHHQS3_k127_2676599_3	497965.Cyan7822_3387	1.335e-103	346.0	COG0549@1|root,COG0549@2|Bacteria,1GAQG@1117|Cyanobacteria,3KJ7G@43988|Cyanothece	1117|Cyanobacteria	E	Belongs to the carbamate kinase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_2676599_2	186497.PF0547	2.725e-178	569.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
GDHHQS3_k127_2676599_1	767817.Desgi_3003	7.634e-189	620.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25ZY7@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS3_k127_2676599_4	479434.Sthe_0538	1.083e-56	205.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_2690461_0	469383.Cwoe_5531	6.178e-95	324.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
GDHHQS3_k127_2690461_3	552811.Dehly_0155	2.816e-23	105.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_2690461_1	479435.Kfla_6159	4.017e-78	277.0	COG0477@1|root,COG2814@2|Bacteria,2H0CW@201174|Actinobacteria,4DN0M@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_2690461_2	987059.RBXJA2T_01620	2.693e-77	270.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS3_k127_2739696_2	1303518.CCALI_02688	5.05e-19	87.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
GDHHQS3_k127_2739696_3	1034769.KB910518_gene4342	7.18e-14	81.0	COG0586@1|root,COG0586@2|Bacteria,1V80V@1239|Firmicutes,4HJVH@91061|Bacilli,26R2E@186822|Paenibacillaceae	91061|Bacilli	S	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,SNARE_assoc
GDHHQS3_k127_2739696_4	1121324.CLIT_10c05000	5.292e-07	59.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia	186801|Clostridia	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS3_k127_2739696_0	926550.CLDAP_21630	8.118e-166	535.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS3_k127_2739696_1	1382356.JQMP01000003_gene2427	5.089e-41	154.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,27XPW@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_2753204_2	944435.AXAJ01000006_gene3922	1.263e-08	66.0	COG0438@1|root,COG0438@2|Bacteria,1PGB1@1224|Proteobacteria,2VIN8@28216|Betaproteobacteria,1KGHP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_2753204_1	926690.KE386573_gene2374	5.991e-19	98.0	COG0500@1|root,arCOG01794@2157|Archaea,2XTKS@28890|Euryarchaeota,23TDP@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_2753204_0	1117379.BABA_20801	1.33e-57	213.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,1ZCCX@1386|Bacillus	91061|Bacilli	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS3_k127_2760544_3	1156844.KB891803_gene2365	4.779e-32	131.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_2760544_1	743721.Psesu_0189	9.118e-54	193.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,1S3YJ@1236|Gammaproteobacteria,1X6S3@135614|Xanthomonadales	135614|Xanthomonadales	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_2760544_2	243164.DET0344	1.094e-44	168.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,34CXD@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
GDHHQS3_k127_2760544_4	293826.Amet_2378	2.981e-10	70.0	arCOG08253@1|root,33GMC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2760544_0	1242864.D187_008994	0.0	1041.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
GDHHQS3_k127_2760544_5	525909.Afer_1489	0.0001355	51.0	COG1714@1|root,COG1714@2|Bacteria,2HGXD@201174|Actinobacteria,4CNXK@84992|Acidimicrobiia	84992|Acidimicrobiia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS3_k127_2763714_0	269799.Gmet_1487	3.148e-119	395.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
GDHHQS3_k127_2763714_1	645991.Sgly_2364	2.962e-19	91.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,260W0@186807|Peptococcaceae	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
GDHHQS3_k127_277079_0	314278.NB231_09548	7.663e-132	439.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS3_k127_277079_1	311424.DhcVS_930	1.489e-92	316.0	COG1173@1|root,COG1173@2|Bacteria,2G9WH@200795|Chloroflexi,34DKE@301297|Dehalococcoidia	301297|Dehalococcoidia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_277079_2	311424.DhcVS_931	5.468e-20	90.0	COG0601@1|root,COG0601@2|Bacteria,2G9WT@200795|Chloroflexi,34DMG@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
GDHHQS3_k127_2784188_6	1380346.JNIH01000006_gene3549	1.081e-05	57.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
GDHHQS3_k127_2784188_4	479434.Sthe_1819	3.246e-29	123.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS3_k127_2784188_5	1230460.C495_11989	1.049e-21	105.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XWRG@28890|Euryarchaeota,23VI0@183963|Halobacteria	183963|Halobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_2784188_2	1429916.X566_14890	3.18e-68	243.0	COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS3_k127_2784188_3	247633.GP2143_17206	3.316e-47	186.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,1T3J3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_2784188_1	1448389.BAVQ01000002_gene2863	8.008e-89	297.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
GDHHQS3_k127_2784188_0	857293.CAAU_1063	7.644e-197	623.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,36EAY@31979|Clostridiaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_2826299_1	316274.Haur_3883	1.823e-81	283.0	COG0240@1|root,COG0240@2|Bacteria,2G5W5@200795|Chloroflexi	200795|Chloroflexi	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS3_k127_2826299_2	525904.Tter_1757	1.696e-42	163.0	COG0344@1|root,COG0344@2|Bacteria,2NPME@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS3_k127_2826299_0	760568.Desku_1838	4.558e-121	406.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS3_k127_2826299_3	926567.TheveDRAFT_0710	0.0001028	47.0	COG4856@1|root,COG4856@2|Bacteria,3TAXK@508458|Synergistetes	508458|Synergistetes	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS3_k127_2877234_0	926569.ANT_25700	1.034e-76	280.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS3_k127_2916233_3	177437.HRM2_19940	3.278e-05	52.0	COG0438@1|root,COG0438@2|Bacteria,1NCUN@1224|Proteobacteria,42WRQ@68525|delta/epsilon subdivisions,2WS5Y@28221|Deltaproteobacteria,2MN5B@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_2916233_0	552811.Dehly_1373	1.565e-47	182.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,34CXC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
GDHHQS3_k127_2916233_2	234267.Acid_4447	8.763e-39	162.0	COG2071@1|root,COG2071@2|Bacteria,3Y5MA@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS3_k127_2916233_1	1313301.AUGC01000005_gene328	2.27e-44	164.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_2953838_2	909663.KI867150_gene75	1.457e-22	100.0	COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions,2WJMQ@28221|Deltaproteobacteria,2MRAU@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GDHHQS3_k127_2953838_0	1242864.D187_006463	7.209e-129	419.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_2953838_1	1499967.BAYZ01000069_gene1845	6.321e-90	306.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_2960845_1	760192.Halhy_0125	8.938e-60	211.0	COG0652@1|root,COG0652@2|Bacteria,4PM5K@976|Bacteroidetes,1IYDR@117747|Sphingobacteriia	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
GDHHQS3_k127_2960845_2	765420.OSCT_0264	1.798e-43	169.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi,375JG@32061|Chloroflexia	32061|Chloroflexia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS3_k127_2960845_0	96561.Dole_3134	1.664e-109	361.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2WKVB@28221|Deltaproteobacteria,2MHKN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
GDHHQS3_k127_2960845_3	656024.FsymDg_2143	1.219e-40	157.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4ESVT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
GDHHQS3_k127_2988547_1	639282.DEFDS_0035	5.053e-09	57.0	COG0359@1|root,COG0359@2|Bacteria,2GFW3@200930|Deferribacteres	200930|Deferribacteres	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS3_k127_2988547_0	643648.Slip_0601	1.905e-126	422.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,42KE4@68298|Syntrophomonadaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
GDHHQS3_k127_3007515_1	429009.Adeg_0177	4.178e-56	206.0	COG1067@1|root,COG1674@1|root,COG1067@2|Bacteria,COG1674@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,42FSR@68295|Thermoanaerobacterales	186801|Clostridia	O	Endopeptidase La	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
GDHHQS3_k127_3007515_0	552811.Dehly_0924	2.572e-124	407.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi,34D4B@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_3015723_1	1380394.JADL01000002_gene1437	6.96e-17	82.0	2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3015723_3	1463854.JOHT01000017_gene3032	9.148e-09	62.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS3_k127_3015723_2	1118153.MOY_00380	2.824e-16	88.0	2DTTQ@1|root,33MKH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3015723_0	1382356.JQMP01000003_gene2339	1.559e-306	953.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS3_k127_3015723_4	97096.XP_007790858.1	5.238e-07	58.0	2CYWP@1|root,2S6X4@2759|Eukaryota,3AAJF@33154|Opisthokonta,3P74E@4751|Fungi,3QZ8J@4890|Ascomycota,21CDB@147550|Sordariomycetes	4751|Fungi	S	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
GDHHQS3_k127_3020244_1	1123060.JONP01000003_gene489	5.565e-99	335.0	COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria,2JR3H@204441|Rhodospirillales	204441|Rhodospirillales	C	TIGRFAM CitB domain protein	-	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_3020244_0	936455.KI421499_gene5042	2.439e-179	575.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,3JQYS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
GDHHQS3_k127_3024600_0	1303518.CCALI_01654	0.0	1277.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria	2|Bacteria	E	L-glutamate biosynthetic process	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS3_k127_302723_2	443218.AS9A_1828	1.488e-26	115.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,232SY@1762|Mycobacteriaceae	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_302723_0	525904.Tter_0977	0.0	1319.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
GDHHQS3_k127_302723_3	401526.TcarDRAFT_1914	1.023e-23	115.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,4H46N@909932|Negativicutes	909932|Negativicutes	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GDHHQS3_k127_302723_4	857293.CAAU_2344	8.29e-20	96.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,36MCG@31979|Clostridiaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS3_k127_302723_1	926566.Terro_4363	5.187e-92	312.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
GDHHQS3_k127_3036246_6	285535.JOEY01000086_gene7198	2.843e-44	173.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_3036246_3	485913.Krac_10252	1.212e-77	274.0	COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GDHHQS3_k127_3036246_1	1183438.GKIL_1701	2.547e-107	357.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria	1117|Cyanobacteria	P	Sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GDHHQS3_k127_3036246_2	479434.Sthe_0789	5.112e-96	329.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi,27XEW@189775|Thermomicrobia	189775|Thermomicrobia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS3_k127_3036246_4	1463936.JOJI01000023_gene1569	1.573e-68	251.0	COG3393@1|root,COG3393@2|Bacteria,2I5TP@201174|Actinobacteria	201174|Actinobacteria	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3036246_0	309801.trd_0371	2.526e-113	386.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi,27XTV@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
GDHHQS3_k127_3036246_7	1128421.JAGA01000002_gene621	3.919e-40	159.0	COG1877@1|root,COG1877@2|Bacteria,2NPXY@2323|unclassified Bacteria	2|Bacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
GDHHQS3_k127_3036246_9	667014.Thein_0352	1.146e-09	69.0	COG0857@1|root,COG0857@2|Bacteria,2GHJ8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
GDHHQS3_k127_3036246_5	313589.JNB_14478	8.227e-68	232.0	2AKGE@1|root,30DHP@2|Bacteria,2I885@201174|Actinobacteria,4FH35@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3036246_8	309801.trd_0198	6.384e-29	124.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,27Y98@189775|Thermomicrobia	189775|Thermomicrobia	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
GDHHQS3_k127_3041239_3	443152.MDG893_15240	1.212e-24	106.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,1RYIP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GDHHQS3_k127_3041239_0	1134413.ANNK01000089_gene360	8.915e-119	397.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_3041239_5	395495.Lcho_3449	6.925e-10	69.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,1KM73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS3_k127_3041239_4	330214.NIDE1837	2.229e-23	103.0	28YNP@1|root,2ZKGB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3041239_2	1278073.MYSTI_07186	2.06e-38	151.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
GDHHQS3_k127_3041239_1	861299.J421_0149	5.814e-50	185.0	COG0122@1|root,COG0122@2|Bacteria,1ZTST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS3_k127_3055774_1	1267535.KB906767_gene3518	9.024e-68	239.0	COG0577@1|root,COG0577@2|Bacteria,3Y4C7@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3055774_0	1267535.KB906767_gene3517	2.106e-89	304.0	COG0577@1|root,COG0577@2|Bacteria,3Y4MY@57723|Acidobacteria,2JMXU@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3092507_2	1521187.JPIM01000018_gene438	1.76e-21	99.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi,375GZ@32061|Chloroflexia	32061|Chloroflexia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
GDHHQS3_k127_3092507_1	1128421.JAGA01000001_gene2135	8.81e-38	153.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.11.1,5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K12132	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS3_k127_3092507_0	479434.Sthe_1558	1.793e-83	287.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,27XHJ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS3_k127_3093515_0	765420.OSCT_1472	1.072e-60	221.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_3093515_1	2074.JNYD01000025_gene549	1.651e-45	177.0	COG0235@1|root,COG0235@2|Bacteria,2IJ2Q@201174|Actinobacteria,4ECZ0@85010|Pseudonocardiales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	ko:K10622	ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220	M00539	R02763,R05377	RC00779	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
GDHHQS3_k127_3093515_2	525904.Tter_1281	4.134e-42	161.0	COG2353@1|root,COG2353@2|Bacteria,2NPJW@2323|unclassified Bacteria	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_3119976_4	485913.Krac_8264	3.288e-10	66.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS3_k127_3119976_1	926550.CLDAP_01110	2.892e-88	312.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_3119976_2	255470.cbdbA1363	2.489e-51	192.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,34D5Y@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS3_k127_3119976_3	926550.CLDAP_04380	3.089e-38	159.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS3_k127_3119976_0	479434.Sthe_1003	9.429e-168	532.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_3125771_3	552811.Dehly_0308	4.549e-21	95.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,34CYZ@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
GDHHQS3_k127_3125771_1	1382306.JNIM01000001_gene724	1.226e-65	236.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GDHHQS3_k127_3125771_2	1254432.SCE1572_18590	3.312e-29	121.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,42UNH@68525|delta/epsilon subdivisions,2WQQJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GDHHQS3_k127_3125771_0	309801.trd_0440	5.906e-155	499.0	COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS3_k127_3130789_3	646529.Desaci_4419	9.02e-45	174.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,262W8@186807|Peptococcaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GDHHQS3_k127_3130789_2	979556.MTES_0569	3.906e-75	259.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4FKZ2@85023|Microbacteriaceae	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
GDHHQS3_k127_3130789_4	1382304.JNIL01000001_gene2286	2.171e-24	119.0	COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3130789_5	1123229.AUBC01000020_gene4391	5.078e-21	108.0	COG0747@1|root,COG0747@2|Bacteria,1PUV0@1224|Proteobacteria,2TVJT@28211|Alphaproteobacteria,3K2PZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_3130789_1	1134413.ANNK01000091_gene77	1.151e-89	308.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes,4HDDV@91061|Bacilli,1ZEPT@1386|Bacillus	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_3133361_3	926550.CLDAP_10820	3.712e-14	84.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
GDHHQS3_k127_3133361_2	1382306.JNIM01000001_gene3511	1.312e-96	331.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS3_k127_3133361_0	867845.KI911784_gene431	2.645e-215	685.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_3133361_1	59538.XP_005969847.1	3.38e-115	379.0	COG0002@1|root,KOG4354@2759|Eukaryota,3AKK9@33154|Opisthokonta,3BVWE@33208|Metazoa,3DBY0@33213|Bilateria	33208|Metazoa	E	Bifunctional protein argC, mitochondrial-like	-	-	-	-	-	-	-	-	-	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_3141638_0	1382306.JNIM01000001_gene298	7.757e-188	607.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
GDHHQS3_k127_3141638_1	62928.azo1490	1.132e-115	404.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV1U@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Response_reg
GDHHQS3_k127_3142440_5	868864.Dester_1226	0.0004512	44.0	COG1191@1|root,COG1191@2|Bacteria,2G45C@200783|Aquificae	200783|Aquificae	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_3142440_1	1380391.JIAS01000018_gene1051	4.413e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1R3U8@1224|Proteobacteria,2U1SI@28211|Alphaproteobacteria,2JW7N@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_3142440_2	1120949.KB903322_gene2739	2.399e-58	206.0	COG3832@1|root,COG3832@2|Bacteria,2HWRC@201174|Actinobacteria,4DK2R@85008|Micromonosporales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_3142440_0	644283.Micau_1285	5.548e-83	284.0	arCOG07533@1|root,3167U@2|Bacteria,2INR8@201174|Actinobacteria,4DMXK@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_3142440_4	1267535.KB906767_gene2250	1.152e-15	86.0	COG2820@1|root,COG2820@2|Bacteria	2|Bacteria	F	uridine phosphorylase activity	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_3142440_3	1499686.BN1079_01550	6.462e-52	199.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_3163934_0	637389.Acaty_c0615	6.088e-177	576.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,2NC2E@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_3163934_1	1382306.JNIM01000001_gene1380	2.717e-26	115.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS3_k127_3163934_2	1410609.JHVB01000004_gene478	1.474e-16	84.0	COG0766@1|root,COG0766@2|Bacteria,2J5JB@203691|Spirochaetes	203691|Spirochaetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS3_k127_3164899_0	867845.KI911784_gene3619	3.585e-90	301.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,375C2@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS3_k127_3164899_3	552811.Dehly_1442	8.274e-19	89.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3164899_2	751945.Theos_0126	4.493e-19	88.0	COG1724@1|root,COG1724@2|Bacteria,1WKJQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_3164899_1	1303518.CCALI_00397	2.181e-40	156.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_3189313_3	1041159.AZUW01000009_gene4517	3.254e-53	199.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
GDHHQS3_k127_3189313_2	867845.KI911784_gene607	5.026e-63	223.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_3189313_1	479434.Sthe_1496	6.77e-88	301.0	COG0351@1|root,COG0351@2|Bacteria,2G5R7@200795|Chloroflexi,27XQP@189775|Thermomicrobia	189775|Thermomicrobia	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
GDHHQS3_k127_3189313_0	479434.Sthe_1495	1.457e-104	345.0	COG2022@1|root,COG2022@2|Bacteria,2G6DX@200795|Chloroflexi,27XT9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS3_k127_3189313_4	760568.Desku_0543	5.005e-32	136.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,261I7@186807|Peptococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_3189313_6	1333998.M2A_1134	2.043e-09	62.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2UMNX@28211|Alphaproteobacteria,4BT5I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_3189313_5	1356854.N007_17345	7.329e-19	93.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,278A3@186823|Alicyclobacillaceae	91061|Bacilli	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_3191056_0	765420.OSCT_2500	1.137e-49	183.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3191056_1	1382306.JNIM01000001_gene2812	2.259e-05	49.0	COG5662@1|root,COG5662@2|Bacteria,2G9EH@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_3193296_3	324602.Caur_1317	2.338e-97	337.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_3193296_4	552811.Dehly_0334	2.303e-52	198.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi,34CZI@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GDHHQS3_k127_3193296_5	748658.KB907315_gene2533	1.675e-12	71.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1S6B0@1236|Gammaproteobacteria,1WYPJ@135613|Chromatiales	135613|Chromatiales	P	PFAM Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_3193296_2	1267533.KB906740_gene128	6.52e-107	362.0	COG2141@1|root,COG2141@2|Bacteria,3Y4KK@57723|Acidobacteria,2JJ9T@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM luciferase family oxidoreductase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_3193296_6	1192034.CAP_5443	0.0006326	49.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
GDHHQS3_k127_3193296_0	552811.Dehly_0962	1.237e-129	425.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,34D2S@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_3193296_1	255470.cbdbA1123	2.203e-119	394.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi,34D8M@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS3_k127_3256922_5	1229172.JQFA01000004_gene719	5.362e-28	120.0	COG1853@1|root,COG1853@2|Bacteria,1G2RV@1117|Cyanobacteria,1H7U3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS3_k127_3256922_0	1382306.JNIM01000001_gene3956	5.326e-114	380.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS3_k127_3256922_4	1122939.ATUD01000010_gene2839	1.25e-35	141.0	COG1403@1|root,COG1403@2|Bacteria,2GV0W@201174|Actinobacteria,4CQF2@84995|Rubrobacteria	84995|Rubrobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS3_k127_3256922_3	397291.C804_00124	1.487e-38	148.0	COG0139@1|root,COG0139@2|Bacteria	2|Bacteria	E	phosphoribosyl-AMP cyclohydrolase activity	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
GDHHQS3_k127_3256922_1	429009.Adeg_0317	4.839e-108	355.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,42FAR@68295|Thermoanaerobacterales	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
GDHHQS3_k127_3256922_2	1150469.RSPPHO_01062	2.152e-64	228.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2JPAY@204441|Rhodospirillales	204441|Rhodospirillales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,His_biosynth
GDHHQS3_k127_3275913_4	1297865.APJD01000014_gene436	5.889e-19	96.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TWR2@28211|Alphaproteobacteria,3JVDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3275913_0	1198452.Jab_2c15230	1.354e-94	329.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM EAL domain, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
GDHHQS3_k127_3275913_1	326424.FRAAL5056	7.44e-82	287.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4ESEF@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_3275913_3	404589.Anae109_1425	1.269e-46	184.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_3275913_2	877421.AUJT01000002_gene1207	6.295e-48	185.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27KU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_3275913_6	644283.Micau_3611	4.627e-05	55.0	COG0392@1|root,COG0392@2|Bacteria,2GP8H@201174|Actinobacteria,4DB6J@85008|Micromonosporales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GDHHQS3_k127_3275913_5	105425.BBPL01000003_gene7018	2.517e-08	64.0	COG0500@1|root,COG2226@2|Bacteria,2HERR@201174|Actinobacteria,2NKQT@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_3281183_2	1297865.APJD01000003_gene6426	3.487e-05	47.0	COG2141@1|root,COG2141@2|Bacteria,1PJES@1224|Proteobacteria,2U3CM@28211|Alphaproteobacteria,3JVGM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
GDHHQS3_k127_3281183_0	1116369.KB890024_gene2856	1.182e-109	362.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,43GTY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	dienelactone hydrolase	dlhH	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_3281183_1	1267535.KB906767_gene2308	1.526e-49	182.0	COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS3_k127_3379276_2	552811.Dehly_0249	1.416e-111	379.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GDHHQS3_k127_3379276_6	552811.Dehly_1399	1.192e-14	74.0	2DEPM@1|root,2ZNRD@2|Bacteria,2G9FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3379276_0	1128421.JAGA01000002_gene639	1.596e-265	829.0	COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria	2|Bacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS3_k127_3379276_3	1149133.ppKF707_1405	2.714e-45	175.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
GDHHQS3_k127_3379276_4	1242864.D187_004866	4.068e-29	119.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,4358I@68525|delta/epsilon subdivisions,2WZJK@28221|Deltaproteobacteria,2Z29U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
GDHHQS3_k127_3379276_5	1123242.JH636434_gene3269	1.138e-16	90.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_25
GDHHQS3_k127_3379276_1	479434.Sthe_0389	1.9e-150	482.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_3379276_7	1230476.C207_03985	0.0006291	42.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JSG0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	MA20_22935	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_3380342_1	525904.Tter_1699	1.579e-74	255.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS3_k127_3380342_0	479434.Sthe_1523	1.219e-226	709.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi,27XVW@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_3380342_3	1379698.RBG1_1C00001G0737	1.442e-70	255.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
GDHHQS3_k127_3380342_4	886293.Sinac_5289	5.813e-28	115.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GDHHQS3_k127_3380342_2	266117.Rxyl_0166	8.678e-71	245.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_3397945_5	521674.Plim_3737	3.012e-53	196.0	COG0265@1|root,COG0265@2|Bacteria,2IXU0@203682|Planctomycetes	203682|Planctomycetes	O	typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_3397945_4	1128421.JAGA01000003_gene2778	5.02e-62	228.0	COG0470@1|root,COG0470@2|Bacteria,2NS3K@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III, delta subunit	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GDHHQS3_k127_3397945_2	1382306.JNIM01000001_gene3573	3.408e-64	235.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS3_k127_3397945_9	204536.SULAZ_0450	4.221e-38	147.0	COG1586@1|root,COG1586@2|Bacteria	2|Bacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synth
GDHHQS3_k127_3397945_3	1379698.RBG1_1C00001G0708	3.378e-62	225.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_3397945_11	436308.Nmar_0408	3.885e-21	101.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
GDHHQS3_k127_3397945_6	1286171.EAL2_808p02120	9.735e-51	186.0	COG4430@1|root,COG4430@2|Bacteria,1V1VF@1239|Firmicutes,249ZH@186801|Clostridia,25XQR@186806|Eubacteriaceae	186801|Clostridia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_3397945_15	1122919.KB905558_gene1272	6.294e-12	72.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	DinB_2,Metallophos_2
GDHHQS3_k127_3397945_1	1382356.JQMP01000003_gene2142	1.267e-72	261.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS3_k127_3397945_0	1229780.BN381_100161	5.432e-84	286.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,3UW6Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPase MipZ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_3397945_7	1128421.JAGA01000004_gene2576	2.528e-44	176.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.4,2.7.1.45	ko:K00847,ko:K00852,ko:K00874	ko00030,ko00051,ko00500,ko00520,ko01100,ko01120,ko01200,map00030,map00051,map00500,map00520,map01100,map01120,map01200	M00061,M00308,M00631	R00760,R00867,R01051,R01541,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS3_k127_3397945_10	485913.Krac_8804	6.255e-32	137.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GDHHQS3_k127_3397945_8	311424.DhcVS_910	2.4e-43	171.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,34D1I@301297|Dehalococcoidia	301297|Dehalococcoidia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
GDHHQS3_k127_3397945_12	1293048.CBMB010000010_gene3725	1.232e-20	105.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02556@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria	183963|Halobacteria	S	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS3_k127_3397945_13	1203554.HMPREF1476_02331	2.312e-20	100.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,4PRCS@995019|Sutterellaceae	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS3_k127_3397945_14	1382304.JNIL01000001_gene2236	3.202e-13	76.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,278N4@186823|Alicyclobacillaceae	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS3_k127_3397945_16	929712.KI912613_gene1120	1.835e-10	64.0	COG0230@1|root,COG0230@2|Bacteria,2HH4A@201174|Actinobacteria,4CQS5@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS3_k127_3448072_3	237609.PSAKL28_19910	1.357e-10	73.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GDHHQS3_k127_3448072_2	1500257.JQNM01000014_gene2919	3.587e-43	168.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,4B9MF@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_3448072_1	1123024.AUII01000016_gene1270	1.024e-132	433.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS3_k127_3448072_0	552811.Dehly_0428	7.166e-236	766.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,34CSK@301297|Dehalococcoidia	2|Bacteria	L	DNA-directed DNA polymerase	dnaE2	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.6,2.7.7.7	ko:K00960,ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_3489098_0	1382306.JNIM01000001_gene99	1.446e-26	117.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS3_k127_3489098_1	1340434.AXVA01000005_gene4816	4.119e-20	103.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,1ZBV3@1386|Bacillus	91061|Bacilli	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_3493471_1	383372.Rcas_1739	7.182e-115	399.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,374SN@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C
GDHHQS3_k127_3493471_3	1157634.KB912948_gene6245	1.905e-42	162.0	COG0009@1|root,COG0009@2|Bacteria,2GN4J@201174|Actinobacteria	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS3_k127_3493471_2	240016.ABIZ01000001_gene5892	4.824e-54	192.0	COG0698@1|root,COG0698@2|Bacteria,46STF@74201|Verrucomicrobia,2IUD9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribose/Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
GDHHQS3_k127_3493471_0	1128421.JAGA01000002_gene559	1.737e-129	437.0	COG0126@1|root,COG0126@2|Bacteria,2NNN1@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145,iSbBS512_1146.SbBS512_E3351	PGK
GDHHQS3_k127_3508323_1	379066.GAU_3068	1.259e-33	140.0	COG0627@1|root,COG0627@2|Bacteria,1ZU1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS3_k127_3508323_2	360911.EAT1b_1938	2.303e-11	74.0	COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_3508323_0	552811.Dehly_0898	1.393e-52	190.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	MA20_27970	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_3531918_0	1382306.JNIM01000001_gene706	6.089e-108	363.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS3_k127_3543638_2	264198.Reut_B5219	1.319e-42	168.0	COG0583@1|root,COG0583@2|Bacteria,1RHTP@1224|Proteobacteria,2VST6@28216|Betaproteobacteria,1KGGY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS3_k127_3543638_1	94624.Bpet0051	1.443e-80	280.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T6GH@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
GDHHQS3_k127_3543638_0	1205680.CAKO01000019_gene39	2.032e-144	467.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TT96@28211|Alphaproteobacteria,2JWK1@204441|Rhodospirillales	204441|Rhodospirillales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS3_k127_354735_1	1267533.KB906738_gene2164	3.715e-110	364.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
GDHHQS3_k127_354735_4	1121456.ATVA01000013_gene1075	4.926e-20	100.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2MDG6@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS3_k127_354735_0	1521187.JPIM01000006_gene1740	2.822e-132	445.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_354735_2	1283299.AUKG01000003_gene513	3.638e-105	348.0	COG2048@1|root,COG2048@2|Bacteria,2H014@201174|Actinobacteria,4CPAS@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
GDHHQS3_k127_354735_3	1131269.AQVV01000001_gene1358	5.49e-65	230.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS3_k127_3564591_3	479434.Sthe_2506	1.917e-37	149.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_3564591_0	1123405.AUMM01000010_gene1224	5.701e-222	700.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_3564591_1	760568.Desku_1363	8.176e-45	168.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS3_k127_3564591_2	1382356.JQMP01000004_gene530	4.529e-39	159.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_3593324_9	378806.STAUR_7881	7.334e-36	151.0	COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,42UXK@68525|delta/epsilon subdivisions,2WQNC@28221|Deltaproteobacteria,2YY5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GDHHQS3_k127_3593324_11	1121365.AQXB01000002_gene1516	6.072e-05	55.0	2EAKD@1|root,334P1@2|Bacteria,2HBNN@201174|Actinobacteria,22MR9@1653|Corynebacteriaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS3_k127_3593324_2	1245469.S58_35190	1.149e-111	372.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria,3JQPK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	FMN-dependent dehydrogenase	MA20_37755	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GDHHQS3_k127_3593324_3	1123024.AUII01000020_gene3181	2.002e-104	356.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4E0KC@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
GDHHQS3_k127_3593324_0	518766.Rmar_2461	3.35e-147	477.0	COG0477@1|root,COG2814@2|Bacteria,4PI8A@976|Bacteroidetes,1FJNM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3593324_7	1123024.AUII01000010_gene681	3.926e-58	211.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS3_k127_3593324_8	929556.Solca_0753	1.778e-41	154.0	COG0500@1|root,COG2226@2|Bacteria,4NFRD@976|Bacteroidetes,1IVKT@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_3593324_4	1123278.KB893428_gene110	5.837e-77	263.0	COG0500@1|root,COG2226@2|Bacteria,4NFRD@976|Bacteroidetes,47MKY@768503|Cytophagia	976|Bacteroidetes	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_3593324_6	1340493.JNIF01000003_gene1281	6.993e-71	245.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	M1-798	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
GDHHQS3_k127_3593324_10	1366050.N234_12245	5.512e-28	117.0	2C19F@1|root,32TZS@2|Bacteria,1R3J6@1224|Proteobacteria,2VXS6@28216|Betaproteobacteria,1KISS@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3593324_5	68219.JNXI01000002_gene3959	3.312e-72	259.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3651767_1	1489678.RDMS_04545	1.573e-25	119.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	aacA-aphD	-	2.7.1.190	ko:K17910	-	-	R11229	RC00002,RC00078	ko00000,ko01000,ko01504	-	-	-	APH
GDHHQS3_k127_3651767_0	311424.DhcVS_1164	4.437e-84	284.0	COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,34D0E@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_3660887_2	479434.Sthe_1429	1.362e-19	89.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,27XSS@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS3_k127_3660887_1	1382306.JNIM01000001_gene2563	3.891e-119	395.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_3660887_0	552811.Dehly_1035	2.137e-297	937.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,34D5F@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS3_k127_3666337_0	981369.JQMJ01000004_gene476	2.094e-54	200.0	COG3832@1|root,COG3832@2|Bacteria,2IJNC@201174|Actinobacteria,2NI7B@228398|Streptacidiphilus	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3666337_4	429009.Adeg_0918	2.207e-17	94.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	Host_attach,PP-binding,eRF1_3
GDHHQS3_k127_3666337_5	1123288.SOV_4c07330	3.711e-14	76.0	293WJ@1|root,2ZRBQ@2|Bacteria,1W3SB@1239|Firmicutes,4H8JC@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3666337_2	1206731.BAGB01000164_gene4283	4.117e-38	147.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS3_k127_3666337_3	1206731.BAGB01000164_gene4283	5.53e-31	133.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
GDHHQS3_k127_3666337_1	1356854.N007_08195	4.165e-40	161.0	COG2267@1|root,COG2267@2|Bacteria,1UHRJ@1239|Firmicutes,4IS7F@91061|Bacilli,27AT4@186823|Alicyclobacillaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_3666337_6	1460634.JCM19037_3493	4.727e-05	54.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_3666741_3	1169161.KB897715_gene5515	7.439e-05	55.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GDHHQS3_k127_3666741_1	357808.RoseRS_2334	2.675e-118	393.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,375D2@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS3_k127_3666741_2	1365176.N186_00425	2.427e-18	89.0	arCOG03743@1|root,arCOG03743@2157|Archaea,2XS5J@28889|Crenarchaeota	28889|Crenarchaeota	O	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
GDHHQS3_k127_3666741_0	909663.KI867150_gene1212	3.84e-175	556.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MSIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_3669786_1	552811.Dehly_0937	3.985e-109	361.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,34D01@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS3_k127_3669786_4	1380408.AVGH01000030_gene142	8.261e-17	88.0	COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,21UZZ@150247|Anoxybacillus	91061|Bacilli	J	Protein of unknown function (DUF402)	ygaC	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GDHHQS3_k127_3669786_3	1122138.AQUZ01000019_gene8179	7.534e-24	113.0	COG2890@1|root,COG2890@2|Bacteria,2I3R2@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS3_k127_3669786_0	552811.Dehly_1020	1.09e-186	600.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,34CN0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS3_k127_3669786_2	926569.ANT_29010	2.116e-93	315.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3669786_5	5722.XP_001309331.1	6.573e-05	53.0	2EZJG@1|root,2T0VX@2759|Eukaryota	5722.XP_001309331.1|-	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3703534_1	1316927.ATKI01000145_gene3973	6.564e-66	251.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1YPHH@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	C	formate dehydrogenase	fdhF	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iECBD_1354.ECBD_3953	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_3703534_3	469371.Tbis_0320	1.878e-23	107.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4E32N@85010|Pseudonocardiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS3_k127_3703534_2	1037409.BJ6T_11710	1.632e-31	132.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,3JTWA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	MA20_22080	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS3_k127_3703534_0	296587.XP_002507213.1	7.046e-71	261.0	28MA4@1|root,2QTTH@2759|Eukaryota,381A0@33090|Viridiplantae,34N20@3041|Chlorophyta	3041|Chlorophyta	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
GDHHQS3_k127_3727688_1	479434.Sthe_1996	1.666e-65	234.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_3727688_0	1382356.JQMP01000004_gene472	2.046e-97	336.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,27XZI@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_3727688_2	1235797.C816_02603	1.58e-08	64.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,2N6Q3@216572|Oscillospiraceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS3_k127_3744183_0	290397.Adeh_3427	8.552e-114	379.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2YZJS@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS3_k127_3744183_1	867845.KI911784_gene1735	6.74e-47	194.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia	32061|Chloroflexia	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
GDHHQS3_k127_3750210_2	926692.AZYG01000064_gene1000	9.38e-102	343.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,3WACN@53433|Halanaerobiales	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GDHHQS3_k127_3750210_8	525904.Tter_0916	8.467e-11	65.0	COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS3_k127_3750210_3	357808.RoseRS_0725	5.911e-96	334.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,375DK@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_3750210_4	326427.Cagg_0597	5.368e-82	288.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,3759R@32061|Chloroflexia	32061|Chloroflexia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS3_k127_3750210_6	1382306.JNIM01000001_gene3871	1.948e-36	145.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS3_k127_3750210_0	357808.RoseRS_0659	5.1e-224	749.0	COG0457@1|root,COG5427@1|root,COG0457@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,37551@32061|Chloroflexia	32061|Chloroflexia	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
GDHHQS3_k127_3750210_7	765420.OSCT_1178	1.76e-18	100.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,376E7@32061|Chloroflexia	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3750210_1	1382306.JNIM01000001_gene4155	2.645e-132	430.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_3750210_5	525904.Tter_0978	1.651e-55	198.0	COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria	2|Bacteria	L	HNH endonuclease	MA20_20605	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS3_k127_3755503_1	1128421.JAGA01000003_gene3195	1.384e-48	187.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
GDHHQS3_k127_3755503_0	1248760.ANFZ01000007_gene2877	2.36e-66	236.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria,2K504@204457|Sphingomonadales	204457|Sphingomonadales	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS3_k127_3755503_2	1280954.HPO_17345	1.602e-21	96.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2U948@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS3_k127_3775050_2	552811.Dehly_1038	2.979e-24	105.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,34DF5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS3_k127_3775050_0	552811.Dehly_1039	2.643e-193	614.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,34CJK@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS3_k127_3775050_4	383372.Rcas_1008	0.0001425	47.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
GDHHQS3_k127_3775050_3	113355.CM001775_gene417	4.022e-12	68.0	COG1724@1|root,COG1724@2|Bacteria,1G9HN@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_3775050_1	1128421.JAGA01000002_gene1310	3.682e-59	210.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_3786962_0	357808.RoseRS_1455	4.294e-166	534.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,374W3@32061|Chloroflexia	32061|Chloroflexia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS3_k127_3786962_3	1333998.M2A_2149	6.203e-10	68.0	COG0454@1|root,COG0456@2|Bacteria,1N3HR@1224|Proteobacteria,2UCRS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3786962_5	1148.1651732	2.932e-05	55.0	COG0494@1|root,COG0494@2|Bacteria,1G1E4@1117|Cyanobacteria,1H5R3@1142|Synechocystis	1117|Cyanobacteria	L	NUDIX domain	mutT	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
GDHHQS3_k127_3786962_1	448385.sce3456	2.883e-110	372.0	COG0604@1|root,COG0604@2|Bacteria,1R2DZ@1224|Proteobacteria,43DM8@68525|delta/epsilon subdivisions,2X65T@28221|Deltaproteobacteria,2Z39E@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_3786962_2	479434.Sthe_1877	6.006e-79	268.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS3_k127_3786962_4	979556.MTES_1733	4.202e-09	59.0	COG2026@1|root,COG2026@2|Bacteria,2IRES@201174|Actinobacteria,4FQCX@85023|Microbacteriaceae	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS3_k127_3789268_0	926569.ANT_19040	1.221e-28	119.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3789268_1	926569.ANT_19030	1.314e-28	116.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS3_k127_3791570_0	931627.MycrhDRAFT_4826	1.579e-69	254.0	COG0477@1|root,COG2814@2|Bacteria,2I9ET@201174|Actinobacteria,2392T@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3791570_1	292459.STH2528	1.146e-22	104.0	COG1595@1|root,COG1595@2|Bacteria,1VD37@1239|Firmicutes,25BCE@186801|Clostridia	186801|Clostridia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_3791570_4	316274.Haur_0685	1.959e-15	78.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_3791570_3	234267.Acid_5657	2.211e-17	86.0	COG5349@1|root,COG5349@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF983)	MA20_36345	-	-	-	-	-	-	-	-	-	-	-	DUF983
GDHHQS3_k127_3791570_2	525904.Tter_0098	2.708e-20	96.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
GDHHQS3_k127_3792311_2	1356854.N007_08195	5.837e-47	180.0	COG2267@1|root,COG2267@2|Bacteria,1UHRJ@1239|Firmicutes,4IS7F@91061|Bacilli,27AT4@186823|Alicyclobacillaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_3792311_0	697281.Mahau_0232	2.812e-103	343.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42EQB@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_3815684_2	555088.DealDRAFT_1141	2.99e-22	111.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3815684_1	243164.DET1458	6.09e-37	155.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,34CXG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3815684_0	997346.HMPREF9374_2972	2.672e-50	186.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,27D2G@186824|Thermoactinomycetaceae	91061|Bacilli	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS3_k127_3815684_3	479434.Sthe_2339	8.278e-06	48.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia	189775|Thermomicrobia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
GDHHQS3_k127_3816810_3	697303.Thewi_1996	1.46e-09	68.0	COG4478@1|root,COG4478@2|Bacteria,1VA1P@1239|Firmicutes,24N7Q@186801|Clostridia,42H0I@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Integral membrane protein 1906	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
GDHHQS3_k127_3816810_0	264732.Moth_0084	1.026e-66	236.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,42FE4@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
GDHHQS3_k127_3816810_1	292459.STH3106	2.073e-20	101.0	COG0526@1|root,COG0526@2|Bacteria,1V2DU@1239|Firmicutes	1239|Firmicutes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
GDHHQS3_k127_3816810_2	330214.NIDE0600	4.698e-11	65.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,3J0VG@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
GDHHQS3_k127_3841317_0	448385.sce3333	1.098e-137	443.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,434SZ@68525|delta/epsilon subdivisions,2WZ41@28221|Deltaproteobacteria,2Z19Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_3841317_3	1500897.JQNA01000002_gene2244	2.168e-16	84.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,1K7QN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
GDHHQS3_k127_3841317_1	644966.Tmar_0517	2.526e-69	248.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,25F0C@186801|Clostridia,3WD52@538999|Clostridiales incertae sedis	186801|Clostridia	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058,ko:K16843	ko00260,ko00270,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513,R05693	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS3_k127_3841317_2	700598.Niako_4637	9.099e-39	150.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes,1IZDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_3850665_0	1489678.RDMS_01850	3.163e-36	152.0	COG0419@1|root,COG0419@2|Bacteria,1WJ38@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
GDHHQS3_k127_3850665_1	768710.DesyoDRAFT_0405	1.623e-06	52.0	COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia,264GV@186807|Peptococcaceae	186801|Clostridia	G	PFAM Isocitrate lyase family	prpB	-	4.1.3.30,4.1.3.32	ko:K03417,ko:K20454	ko00640,ko00760,ko01120,map00640,map00760,map01120	-	R00409,R01355	RC00286,RC00287,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
GDHHQS3_k127_3892048_0	1341151.ASZU01000015_gene2109	2.365e-42	167.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HCR1@91061|Bacilli,27CEN@186824|Thermoactinomycetaceae	91061|Bacilli	S	Peptidase family M28	ywaD	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_3892048_1	926550.CLDAP_09320	9.169e-06	55.0	COG1652@1|root,COG2335@1|root,COG1652@2|Bacteria,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	BTAD,Fasciclin,LysM
GDHHQS3_k127_3902035_1	1284679.HMPREF1626_05580	8.774e-06	55.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D5ND@85005|Actinomycetales	201174|Actinobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS3_k127_3902035_0	316274.Haur_4571	1.844e-98	329.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,374UB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
GDHHQS3_k127_3926031_0	644966.Tmar_2298	7.043e-193	612.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WCDH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_3926031_3	383372.Rcas_4027	2.378e-44	164.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi,375U3@32061|Chloroflexia	32061|Chloroflexia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GDHHQS3_k127_3926031_1	316274.Haur_4915	1.494e-70	244.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GDHHQS3_k127_3926031_2	243164.DET0475	5.214e-53	203.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,34CM4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	50S ribosomal protein L4	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GDHHQS3_k127_3948610_0	1521187.JPIM01000063_gene2477	1.419e-146	472.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi,3756R@32061|Chloroflexia	32061|Chloroflexia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS3_k127_3948610_3	67257.JODR01000002_gene1202	4.989e-13	82.0	COG1807@1|root,COG1807@2|Bacteria,2GP96@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3948610_4	326427.Cagg_0933	1.609e-12	71.0	COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,3760D@32061|Chloroflexia	32061|Chloroflexia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS3_k127_3948610_1	357808.RoseRS_0390	4.394e-60	224.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
GDHHQS3_k127_3948610_2	670487.Ocepr_0837	4.947e-32	130.0	COG0325@1|root,COG0325@2|Bacteria,1WIDP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS3_k127_3948610_5	309801.trd_0819	4.577e-05	51.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,27YGC@189775|Thermomicrobia	189775|Thermomicrobia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS3_k127_3961368_6	1121106.JQKB01000010_gene534	3.134e-19	93.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS3_k127_3961368_2	1211115.ALIQ01000184_gene4161	2.172e-69	244.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3N9R1@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_3961368_3	196162.Noca_0243	3.131e-43	166.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4DNGF@85009|Propionibacteriales	201174|Actinobacteria	S	NADPH-dependent F420 reductase	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS3_k127_3961368_0	1382356.JQMP01000001_gene792	2.25e-93	313.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
GDHHQS3_k127_3961368_4	543632.JOJL01000054_gene212	1.753e-32	137.0	COG3266@1|root,COG3266@2|Bacteria,2HMYI@201174|Actinobacteria,4DD3C@85008|Micromonosporales	201174|Actinobacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS3_k127_3961368_1	479434.Sthe_0282	5.268e-76	270.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_3961368_5	42256.RradSPS_0993	2.68e-26	113.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
GDHHQS3_k127_3962829_0	1304880.JAGB01000002_gene2278	1.359e-56	217.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS3_k127_3962829_1	1007105.PT7_2369	5.747e-12	72.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VMZ3@28216|Betaproteobacteria,3T34Q@506|Alcaligenaceae	28216|Betaproteobacteria	G	Class II aldolase adducin domain protein	fucA_3	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
GDHHQS3_k127_3979596_0	113395.AXAI01000053_gene2640	2.387e-132	443.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
GDHHQS3_k127_3979596_2	861299.J421_2925	3.218e-47	175.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS3_k127_3983946_2	1293048.CBMB010000006_gene3051	2.152e-38	149.0	arCOG08934@1|root,arCOG08934@2157|Archaea,2XXBA@28890|Euryarchaeota	28890|Euryarchaeota	Q	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_3983946_3	1283283.ATXA01000010_gene4631	1.901e-31	134.0	COG1028@1|root,COG1028@2|Bacteria,2GIRG@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_3983946_0	1122915.AUGY01000118_gene6538	2.716e-116	389.0	COG4638@1|root,COG4638@2|Bacteria,1UZWG@1239|Firmicutes,4HBGQ@91061|Bacilli,26VC1@186822|Paenibacillaceae	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_3992234_2	525904.Tter_1814	6.137e-33	132.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS3_k127_3992234_0	255470.cbdbA514	1.338e-135	447.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi,34D09@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS3_k127_3992234_1	243164.DET0539	2.751e-42	164.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi,34CRZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GDHHQS3_k127_4014498_0	525904.Tter_0081	3.38e-115	379.0	COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria	2|Bacteria	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_4014498_1	477974.Daud_0585	5.213e-54	208.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,260HU@186807|Peptococcaceae	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_401644_0	926550.CLDAP_22240	2.514e-110	373.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
GDHHQS3_k127_4051135_2	391625.PPSIR1_29720	1.316e-28	118.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_4051135_4	485913.Krac_10633	8.093e-08	62.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_4051135_1	255470.cbdbA812	6.727e-52	199.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi,34D5M@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
GDHHQS3_k127_4051135_0	311424.DhcVS_737	1.16e-215	684.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_4051135_3	1032480.MLP_33760	7.741e-23	101.0	COG3832@1|root,COG3832@2|Bacteria,2I4FM@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_4181707_0	926569.ANT_00850	5.54e-229	716.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_4183084_4	1304880.JAGB01000003_gene1176	5.071e-35	137.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS3_k127_4183084_2	690850.Desaf_3421	1.619e-43	168.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS3_k127_4183084_1	1128421.JAGA01000002_gene725	9.439e-53	196.0	COG0101@1|root,COG0101@2|Bacteria,2NPEC@2323|unclassified Bacteria	2|Bacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS3_k127_4183084_3	311424.DhcVS_445	3.228e-38	145.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi,34DCI@301297|Dehalococcoidia	301297|Dehalococcoidia	J	structural constituent of ribosome	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS3_k127_4183084_0	485913.Krac_12501	8.828e-92	315.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS3_k127_4183084_5	479434.Sthe_1063	1.313e-30	124.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi,27XMY@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	-	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS3_k127_4184005_1	1303518.CCALI_02688	3.802e-201	640.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
GDHHQS3_k127_4184005_0	525904.Tter_0474	3.755e-292	908.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
GDHHQS3_k127_4196403_5	1121472.AQWN01000005_gene2506	1.202e-89	306.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2608Q@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS3_k127_4196403_11	525904.Tter_1034	2.3e-05	51.0	2ESS5@1|root,33KAI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4196403_10	552811.Dehly_1716	1.151e-27	115.0	2EQ8R@1|root,33HV0@2|Bacteria,2G91J@200795|Chloroflexi,34DHP@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4196403_2	1382306.JNIM01000001_gene1459	3.297e-123	414.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_4196403_7	357808.RoseRS_1135	2.642e-57	213.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi,376NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_4196403_4	326427.Cagg_0828	1.942e-109	368.0	COG0399@1|root,COG0399@2|Bacteria,2G5QG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_4196403_6	368408.Tpen_0895	2.897e-61	220.0	COG0110@1|root,arCOG01848@2157|Archaea,2XQEI@28889|Crenarchaeota	28889|Crenarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GDHHQS3_k127_4196403_3	383372.Rcas_0784	1.775e-121	403.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi,375NM@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS3_k127_4196403_1	643648.Slip_0161	1.138e-123	420.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42JPY@68298|Syntrophomonadaceae	186801|Clostridia	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
GDHHQS3_k127_4196403_9	768710.DesyoDRAFT_5066	4.36e-45	171.0	COG2148@1|root,COG2148@2|Bacteria,1V0FZ@1239|Firmicutes,24F99@186801|Clostridia,26179@186807|Peptococcaceae	186801|Clostridia	M	PFAM Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GDHHQS3_k127_4196403_0	304371.MCP_0774	5.123e-128	431.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,2NAHC@224756|Methanomicrobia	224756|Methanomicrobia	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_4196403_8	330214.NIDE0884	3.485e-47	178.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rhiI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	ko:K15471	-	-	-	-	ko00000,ko01000,ko01008	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_4197703_0	479434.Sthe_0700	2.365e-26	110.0	2E63U@1|root,330SV@2|Bacteria,2G9KB@200795|Chloroflexi,27YPM@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4222583_0	861299.J421_4135	1.114e-16	89.0	COG0515@1|root,COG0515@2|Bacteria,1ZUAC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_4222583_1	460265.Mnod_5227	0.0007365	43.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,1JSA9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoEF	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_4264081_4	1125863.JAFN01000001_gene1580	1.336e-28	121.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
GDHHQS3_k127_4264081_0	525904.Tter_0963	8.3e-130	428.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_4264081_2	1382306.JNIM01000001_gene527	2.086e-50	190.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS3_k127_4264081_3	1296416.JACB01000062_gene3855	1.167e-39	158.0	2A83Q@1|root,30X4E@2|Bacteria,4PAG5@976|Bacteroidetes,1IM5T@117743|Flavobacteriia,2YGWC@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4264081_1	485913.Krac_10815	5.396e-75	258.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS3_k127_4298858_1	269799.Gmet_2198	1.74e-36	145.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_4298858_0	1205680.CAKO01000040_gene492	6.122e-109	354.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TR5N@28211|Alphaproteobacteria,2JQT2@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
GDHHQS3_k127_4308566_6	1382306.JNIM01000001_gene3739	1.106e-30	129.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS3_k127_4308566_8	1131269.AQVV01000003_gene690	3.191e-14	74.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS3_k127_4308566_1	765420.OSCT_0164	4.776e-75	264.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS3_k127_4308566_0	477974.Daud_0642	8.742e-85	288.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_4308566_5	926569.ANT_14610	1.268e-33	134.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS3_k127_4308566_7	552811.Dehly_0305	3.132e-24	104.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi,34DGE@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_4308566_2	1184607.AUCHE_17_00200	2.253e-58	216.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4F6E4@85018|Dermatophilaceae	201174|Actinobacteria	O	Cytochrome C assembly protein	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GDHHQS3_k127_4308566_3	309801.trd_1042	1.705e-53	199.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XV7@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_4308566_4	316274.Haur_2249	1.431e-48	180.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4360385_1	1209989.TepiRe1_2654	1.643e-59	213.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS3_k127_4360385_0	1303518.CCALI_00114	3.091e-132	431.0	COG0505@1|root,COG0505@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
GDHHQS3_k127_4360385_3	671143.DAMO_1704	1.499e-09	64.0	COG1487@1|root,COG1487@2|Bacteria,2NRNI@2323|unclassified Bacteria	2|Bacteria	S	Large family of predicted nucleotide-binding domains	vapC	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_4360385_2	552811.Dehly_0915	3.333e-31	123.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,34D66@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS3_k127_4372462_2	101510.RHA1_ro00086	4.749e-31	136.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FW39@85025|Nocardiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_4372462_5	1206720.BAFQ01000050_gene1184	1.839e-12	70.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4G36I@85025|Nocardiaceae	201174|Actinobacteria	H	ThiS family	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_4372462_1	926550.CLDAP_06500	3.31e-62	220.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_4372462_0	926550.CLDAP_06510	7.387e-77	267.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_4372462_6	3712.Bo3g127600.1	1.919e-12	70.0	2E4EA@1|root,2S5QZ@2759|Eukaryota,38A44@33090|Viridiplantae,3GWQ7@35493|Streptophyta,3I1HA@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4375887_0	429009.Adeg_0470	4.415e-91	308.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,42ET8@68295|Thermoanaerobacterales	186801|Clostridia	G	Transketolase, central region	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS3_k127_4375887_1	1394178.AWOO02000030_gene4677	3.288e-67	249.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4EHBG@85012|Streptosporangiales	201174|Actinobacteria	S	Methyltransferase small domain	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
GDHHQS3_k127_4375887_2	1484157.PSNIH2_21350	1.036e-22	102.0	COG4262@1|root,COG4262@2|Bacteria,1QIFV@1224|Proteobacteria,1TGA7@1236|Gammaproteobacteria,3W1JM@53335|Pantoea	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4378366_1	1340493.JNIF01000004_gene927	1.638e-73	250.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
GDHHQS3_k127_4378366_0	1340493.JNIF01000004_gene928	1.983e-216	682.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
GDHHQS3_k127_4378366_2	1198452.Jab_2c30440	9.971e-05	50.0	2DZUH@1|root,32VJB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4408530_3	1122917.KB899674_gene316	9.633e-26	109.0	COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,4HTUD@91061|Bacilli,277AG@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K02031,ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_4408530_1	1122917.KB899674_gene315	2.166e-101	338.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,26Q9W@186822|Paenibacillaceae	91061|Bacilli	EP	ABC transporter permease	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_4408530_2	1122917.KB899674_gene314	2.004e-99	336.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,26T83@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB1	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_4408530_0	1122917.KB899674_gene313	4.106e-166	537.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_4426455_1	479434.Sthe_1614	1.05e-76	269.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi,27XXX@189775|Thermomicrobia	189775|Thermomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS3_k127_4426455_5	1479238.JQMZ01000001_gene575	1.706e-36	147.0	COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2U4CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
GDHHQS3_k127_4426455_6	246197.MXAN_7387	5.611e-18	97.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
GDHHQS3_k127_4426455_7	1121468.AUBR01000055_gene1416	1.13e-12	76.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,42H4S@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS3_k127_4426455_4	383372.Rcas_1680	5.715e-54	201.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,3766N@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS3_k127_4426455_3	574087.Acear_0237	2.99e-56	208.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,25D46@186801|Clostridia	186801|Clostridia	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS3_k127_4426455_0	867845.KI911784_gene152	7.229e-161	520.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,374Z4@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS3_k127_4426455_2	398512.JQKC01000004_gene5119	4.752e-65	239.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,3WKMS@541000|Ruminococcaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
GDHHQS3_k127_4426455_8	555088.DealDRAFT_3019	2.179e-12	76.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42KSY@68298|Syntrophomonadaceae	186801|Clostridia	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,RcpC,SAF
GDHHQS3_k127_4427933_2	479434.Sthe_2391	2.437e-21	97.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS3_k127_4427933_0	515635.Dtur_0186	2.111e-143	472.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_4427933_1	153721.MYP_5008	5.338e-35	139.0	28M8W@1|root,2ZAMX@2|Bacteria,4NHJF@976|Bacteroidetes,47W3F@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
GDHHQS3_k127_4438136_2	338963.Pcar_0765	6.58e-45	172.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,43B63@68525|delta/epsilon subdivisions,2X6JM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_4438136_0	702113.PP1Y_AT15873	3.809e-87	299.0	COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2U4H1@28211|Alphaproteobacteria,2K3XM@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
GDHHQS3_k127_4438136_1	525904.Tter_0978	1.336e-58	209.0	COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria	2|Bacteria	L	HNH endonuclease	MA20_20605	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS3_k127_4449981_4	311424.DhcVS_1233	1.444e-11	67.0	COG2159@1|root,COG2159@2|Bacteria,2G6CW@200795|Chloroflexi,34CYX@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS3_k127_4449981_1	596152.DesU5LDRAFT_0469	4.863e-60	217.0	COG0730@1|root,COG0730@2|Bacteria,1Q59Y@1224|Proteobacteria,430VR@68525|delta/epsilon subdivisions,2WVKN@28221|Deltaproteobacteria,2M8GD@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_4449981_5	396588.Tgr7_0220	2.8e-08	61.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_4449981_3	755178.Cyan10605_3439	9.384e-43	169.0	COG0805@1|root,COG0805@2|Bacteria,1FZZ8@1117|Cyanobacteria	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS3_k127_4449981_0	311424.DhcVS_379	3.01e-70	244.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,34CY0@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_4449981_2	311424.DhcVS_380	8.453e-46	168.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,34CSJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GDHHQS3_k127_4450660_1	1123023.JIAI01000018_gene2512	4.532e-60	221.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.16	ko:K05713	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R04376,R06788	RC01140,RC01364	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
GDHHQS3_k127_4450660_0	1283287.KB822577_gene3388	2.716e-69	240.0	COG2128@1|root,COG2128@2|Bacteria,2IBNX@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS3_k127_4465552_0	639282.DEFDS_0235	2.407e-111	365.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS3_k127_4465552_1	290397.Adeh_2884	1.541e-80	281.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42SJR@68525|delta/epsilon subdivisions,2WRRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_4494753_1	479434.Sthe_0792	2.417e-55	199.0	COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi,27XYM@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_4494753_0	1382306.JNIM01000001_gene1345	2.568e-66	231.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS3_k127_4494753_2	309801.trd_A0609	2.851e-28	123.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_4494753_3	479432.Sros_2467	3.422e-23	102.0	COG1670@1|root,COG1670@2|Bacteria,2II7F@201174|Actinobacteria,4EJXA@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_4504110_3	710686.Mycsm_02767	8.231e-40	152.0	COG4420@1|root,COG4420@2|Bacteria,2INCC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS3_k127_4504110_0	316274.Haur_3367	3.596e-164	530.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GDHHQS3_k127_4504110_5	471852.Tcur_2101	7.74e-25	121.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4EHU2@85012|Streptosporangiales	201174|Actinobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_4504110_4	479434.Sthe_1443	2.888e-35	154.0	COG1560@1|root,COG1560@2|Bacteria,2G9GW@200795|Chloroflexi,27Z5D@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_4504110_2	1382306.JNIM01000001_gene4122	6.483e-42	167.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GDHHQS3_k127_4504110_1	255470.cbdbA942	6.903e-73	259.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,34CIQ@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4519653_1	243164.DET1257	3.452e-53	200.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi,34CWW@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_4519653_0	926550.CLDAP_24290	3.15e-217	700.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
GDHHQS3_k127_4520922_0	1123288.SOV_1c12100	1.397e-105	355.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS3_k127_4520922_8	46234.ANA_C10011	6.876e-26	108.0	COG1724@1|root,COG1724@2|Bacteria,1G890@1117|Cyanobacteria	1117|Cyanobacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_4520922_7	113355.CM001775_gene2973	3.705e-27	114.0	COG1598@1|root,COG1598@2|Bacteria,1G9MA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_4520922_2	290317.Cpha266_0980	1.757e-85	286.0	COG4502@1|root,COG4502@2|Bacteria,1FEF5@1090|Chlorobi	1090|Chlorobi	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
GDHHQS3_k127_4520922_6	1071085.KK033114_gene736	1.402e-49	182.0	arCOG08934@1|root,arCOG08934@2157|Archaea,2XXBA@28890|Euryarchaeota	28890|Euryarchaeota	Q	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_4520922_5	1172181.KB911703_gene212	2.505e-65	234.0	COG0600@1|root,COG0600@2|Bacteria,2HMR9@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter (permease)	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
GDHHQS3_k127_4520922_4	1278078.G419_10457	3.777e-66	235.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FWM1@85025|Nocardiaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GDHHQS3_k127_4520922_3	2074.JNYD01000023_gene1320	1.092e-84	293.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS3_k127_4520922_1	113395.AXAI01000002_gene5235	2.186e-98	330.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_4520922_9	411901.BACCAC_02146	0.0001812	47.0	2A0M7@1|root,30NRH@2|Bacteria,4PB6T@976|Bacteroidetes,2FV5Q@200643|Bacteroidia,4ASDC@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4520922_10	1356854.N007_16675	0.0002496	43.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
GDHHQS3_k127_4521064_1	986075.CathTA2_1248	1.298e-48	188.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
GDHHQS3_k127_4521064_0	1298867.AUES01000029_gene2373	3.205e-120	395.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_4521064_3	1172188.KB911824_gene3347	5.865e-25	107.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria,4FK1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
GDHHQS3_k127_4522782_0	32051.SynWH7803_1476	2.364e-64	237.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1GYEZ@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
GDHHQS3_k127_4522782_1	244581.IM40_06145	1.989e-11	65.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,47FD9@766|Rickettsiales	766|Rickettsiales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS3_k127_4524552_3	118163.Ple7327_1591	1.176e-29	132.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,3VIQD@52604|Pleurocapsales	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
GDHHQS3_k127_4524552_4	632335.Calkr_1612	5.621e-11	65.0	2EQBX@1|root,33HY1@2|Bacteria,1VY28@1239|Firmicutes,2523K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4524552_5	111781.Lepto7376_1088	6.864e-09	63.0	2EQBX@1|root,33HY1@2|Bacteria,1GGCK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4524552_0	195250.CM001776_gene1327	2.734e-104	346.0	COG0338@1|root,COG0338@2|Bacteria,1G0BF@1117|Cyanobacteria,1H0AA@1129|Synechococcus	1117|Cyanobacteria	H	Site-specific DNA-methyltransferase (adenine-specific)	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
GDHHQS3_k127_4524552_2	926569.ANT_27300	1.25e-46	179.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_4524552_1	243164.DET1203	1.787e-56	207.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi,34D0J@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
GDHHQS3_k127_4549322_0	1048339.KB913029_gene4056	1.138e-77	270.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria,4EWE7@85013|Frankiales	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
GDHHQS3_k127_4549322_2	1538295.JY96_16435	2.628e-10	67.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,2VVVW@28216|Betaproteobacteria,1KP7M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4549322_1	75379.Tint_0710	1.901e-55	203.0	COG2203@1|root,COG2203@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria,1KN86@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Pyridoxamine 5'-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
GDHHQS3_k127_4551535_2	255470.cbdbA1394	1.58e-39	150.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,34CMZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_4551535_3	255470.cbdbB11	1.686e-10	70.0	2A4CG@1|root,30SY4@2|Bacteria,2GAT0@200795|Chloroflexi,34DA6@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4551535_1	243164.DET1640	2.206e-67	235.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,34CY4@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_4551535_0	1499684.CCNP01000011_gene183	6.502e-72	249.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_4564842_0	1037409.BJ6T_18820	8.554e-52	188.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,3JRPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_4564842_2	525904.Tter_2149	4.11e-05	52.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2NPCW@2323|unclassified Bacteria	2|Bacteria	PQ	Multicopper oxidase	nirK	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1	ko:K00368,ko:K18683	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,Cytochrom_C,Cytochrome_CBB3
GDHHQS3_k127_4564842_1	1552758.NC00_06290	4.337e-09	66.0	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X71E@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
GDHHQS3_k127_4564842_3	1444310.JANV01000190_gene4066	0.0001282	46.0	29S5T@1|root,30DAB@2|Bacteria,1UB2G@1239|Firmicutes,4IMF9@91061|Bacilli,1ZK0W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4570765_1	1122939.ATUD01000009_gene2975	1.54e-40	154.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CPGQ@84995|Rubrobacteria	84995|Rubrobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS3_k127_4570765_0	469383.Cwoe_5284	3.221e-204	649.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_4570765_2	1042209.HK44_020775	1.448e-05	57.0	2DBRU@1|root,2ZANA@2|Bacteria,1NIAW@1224|Proteobacteria,1SGWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4572391_1	2903.EOD40718	3.154e-72	253.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
GDHHQS3_k127_4572391_4	338966.Ppro_1347	8.982e-37	150.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,43TXZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS3_k127_4572391_0	324602.Caur_2517	1.17e-78	274.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,3750B@32061|Chloroflexia	32061|Chloroflexia	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GDHHQS3_k127_4572391_5	871963.Desdi_2165	4.213e-06	55.0	COG2206@1|root,COG2206@2|Bacteria,1VDUC@1239|Firmicutes,25DNP@186801|Clostridia,262JQ@186807|Peptococcaceae	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_4572391_3	264732.Moth_1362	2.552e-41	161.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,42FD9@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS3_k127_4572391_2	357808.RoseRS_4103	4.469e-50	183.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi,375EY@32061|Chloroflexia	32061|Chloroflexia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS3_k127_4583517_1	1040986.ATYO01000031_gene3157	9.776e-53	194.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,43J44@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GDHHQS3_k127_4583517_0	1038862.KB893873_gene7559	1.004e-76	262.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria,3JVRZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
GDHHQS3_k127_4583517_2	1123401.JHYQ01000014_gene834	8.797e-41	162.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,1SG02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_4617096_3	1242864.D187_006461	1.209e-08	65.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4617096_1	1089550.ATTH01000001_gene1008	1.292e-61	228.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1FIMW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS3_k127_4617096_2	1379698.RBG1_1C00001G1774	8.953e-59	227.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS3_k127_4617096_0	324602.Caur_3597	3.855e-66	252.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,37570@32061|Chloroflexia	32061|Chloroflexia	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
GDHHQS3_k127_4617096_4	479434.Sthe_1589	1.078e-06	52.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,27XZ3@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_4630782_2	1200792.AKYF01000010_gene2860	1.047e-32	136.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,274QP@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_4630782_0	1174684.EBMC1_17272	8.121e-108	368.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,2K8YM@204457|Sphingomonadales	204457|Sphingomonadales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_4630782_1	1411123.JQNH01000001_gene3677	4.335e-68	241.0	COG1712@1|root,COG1712@2|Bacteria,1MX8S@1224|Proteobacteria,2TV48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
GDHHQS3_k127_4630782_3	1030157.AFMP01000040_gene1552	3.141e-32	133.0	COG2267@1|root,COG2267@2|Bacteria,1QW7I@1224|Proteobacteria,2TZB1@28211|Alphaproteobacteria,2KDYD@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_4646612_0	1379698.RBG1_1C00001G1471	2.504e-209	662.0	COG4799@1|root,COG4799@2|Bacteria,2NNWQ@2323|unclassified Bacteria	2|Bacteria	I	carboxyl transferase	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_465459_2	1382356.JQMP01000003_gene2541	1.048e-21	98.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi,27YMW@189775|Thermomicrobia	189775|Thermomicrobia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS3_k127_465459_1	743719.PaelaDRAFT_0941	4.623e-46	176.0	COG1266@1|root,COG1266@2|Bacteria,1TVK4@1239|Firmicutes,4I3C3@91061|Bacilli,273YG@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_465459_3	227882.SAV_7559	1.895e-15	78.0	COG5428@1|root,COG5428@2|Bacteria,2GPCE@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
GDHHQS3_k127_465459_0	1382306.JNIM01000001_gene873	2.142e-105	356.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS3_k127_465710_3	1382356.JQMP01000003_gene1346	3.969e-08	56.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi,27XUP@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS3_k127_465710_1	292564.Cyagr_0461	2.049e-38	156.0	COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,22S2B@167375|Cyanobium	1117|Cyanobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_465710_0	479434.Sthe_1001	1.664e-210	686.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi,27XGW@189775|Thermomicrobia	189775|Thermomicrobia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
GDHHQS3_k127_465710_2	926569.ANT_19690	1.841e-31	127.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_466969_1	472759.Nhal_2490	1.31e-242	766.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
GDHHQS3_k127_466969_0	867845.KI911784_gene1529	0.0	1062.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G7K6@200795|Chloroflexi,374W8@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_4674353_0	1122604.JONR01000001_gene1773	8.816e-70	249.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1SM1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4674353_3	529818.AMSG_06697T0	1.534e-09	67.0	29WS3@1|root,2RXQ6@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4674353_2	1223523.H340_00889	2.565e-28	128.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS3_k127_4674353_1	1173027.Mic7113_2967	2.26e-31	134.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	2|Bacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_468256_6	311424.DhcVS_296	3.861e-30	128.0	2A4RY@1|root,30TDC@2|Bacteria,2GB08@200795|Chloroflexi,34DPC@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_468256_3	311424.DhcVS_298	3.349e-60	232.0	2BPNS@1|root,32IFU@2|Bacteria,2GAX7@200795|Chloroflexi,34DII@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_468256_8	243164.DET0356	1.128e-09	61.0	2A3V0@1|root,30SD1@2|Bacteria,2GAY5@200795|Chloroflexi,34DJT@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_468256_1	311424.DhcVS_545	7.179e-149	478.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi,34D5N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS3_k127_468256_5	761193.Runsl_1074	2.443e-32	134.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,47R8R@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS3_k127_468256_4	573370.DMR_03550	1.627e-32	130.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,431UE@68525|delta/epsilon subdivisions,2WWKK@28221|Deltaproteobacteria,2MBP1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_468256_0	1382306.JNIM01000001_gene2616	2.293e-171	559.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_468256_2	485913.Krac_2496	6.34e-65	225.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_4708461_4	867903.ThesuDRAFT_01258	4.131e-43	165.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4708461_7	1121413.JMKT01000014_gene2470	6.918e-18	89.0	COG3448@1|root,COG3448@2|Bacteria,1NQ52@1224|Proteobacteria	1224|Proteobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
GDHHQS3_k127_4708461_0	1382306.JNIM01000001_gene3339	2.793e-253	794.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS3_k127_4708461_8	439375.Oant_3599	1.886e-16	94.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,1J1SX@118882|Brucellaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS3_k127_4708461_6	521674.Plim_3666	1.663e-18	94.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS3_k127_4708461_3	525904.Tter_0889	2.08e-62	223.0	COG0730@1|root,COG0730@2|Bacteria,2NP64@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_4708461_1	525904.Tter_0037	1.27e-89	302.0	COG0175@1|root,COG0175@2|Bacteria,2NPHM@2323|unclassified Bacteria	2|Bacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
GDHHQS3_k127_4708461_2	525904.Tter_0038	3.051e-80	270.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
GDHHQS3_k127_4708461_5	1382306.JNIM01000001_gene2598	5.233e-36	141.0	COG2046@1|root,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
GDHHQS3_k127_472783_2	525904.Tter_0464	3.672e-32	141.0	COG0405@1|root,COG0405@2|Bacteria,2NP14@2323|unclassified Bacteria	2|Bacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_472783_0	1134413.ANNK01000144_gene3829	2.598e-60	218.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,1ZCSW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ywfH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0016999,GO:0017000,GO:0017144,GO:0036094,GO:0044237,GO:0044249,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.1.1.100	ko:K00059,ko:K19550	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11067,R11671	RC00029,RC00117,RC03342	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_472783_4	158500.BV97_00677	9.781e-11	71.0	COG1357@1|root,COG1357@2|Bacteria,1RFRV@1224|Proteobacteria,2U7UC@28211|Alphaproteobacteria,2K1MF@204457|Sphingomonadales	204457|Sphingomonadales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS3_k127_472783_1	485913.Krac_4886	6.772e-36	153.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	tetV	-	-	ko:K18215	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.3	-	-	MFS_1,MFS_3
GDHHQS3_k127_472783_3	1068980.ARVW01000001_gene4346	9.319e-30	129.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E1FH@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_4729352_1	450380.JPSY01000001_gene1246	2.356e-28	116.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GDHHQS3_k127_4729352_0	882.DVU_0192	8.514e-79	276.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,42X97@68525|delta/epsilon subdivisions,2WNMY@28221|Deltaproteobacteria,2MA3E@213115|Desulfovibrionales	28221|Deltaproteobacteria	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
GDHHQS3_k127_4734337_2	1532557.JL37_15960	5.349e-70	251.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2VQ87@28216|Betaproteobacteria,3T2ZG@506|Alcaligenaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	hcaE	-	1.14.12.11,1.14.12.19,1.14.12.3	ko:K03268,ko:K05708	ko00360,ko00361,ko00362,ko00623,ko00625,ko01100,ko01120,ko01220,map00360,map00361,map00362,map00623,map00625,map01100,map01120,map01220	M00545,M00547	R03543,R03559,R05429,R06782,R06783,R06831,R06856,R09151,R09152	RC00098,RC00267,RC00951,RC03011,RC03012,RC03013	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_4734337_3	1038859.AXAU01000014_gene1411	1.366e-48	183.0	COG5517@1|root,COG5517@2|Bacteria,1RANS@1224|Proteobacteria,2TVWG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Ring_hydroxyl_B
GDHHQS3_k127_4734337_0	1122609.AUGT01000032_gene452	1.089e-130	433.0	COG0154@1|root,COG0154@2|Bacteria,2I9DH@201174|Actinobacteria	201174|Actinobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GDHHQS3_k127_4734337_5	1195236.CTER_2057	2.013e-08	64.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3WI51@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_4734337_1	867845.KI911784_gene881	3.102e-116	384.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_4734337_4	1122917.KB899674_gene316	1.793e-34	136.0	COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,4HTUD@91061|Bacilli,277AG@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K02031,ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_4771741_1	1380391.JIAS01000018_gene1050	8.045e-52	192.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,2JS6T@204441|Rhodospirillales	204441|Rhodospirillales	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GDHHQS3_k127_4771741_2	292459.STH3082	7.057e-37	147.0	COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,24KC2@186801|Clostridia	186801|Clostridia	J	methyltransferase small	-	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
GDHHQS3_k127_4771741_0	1128421.JAGA01000002_gene1016	3.835e-90	310.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS3_k127_4784228_8	1268303.RHODMAR_1187	4.379e-30	130.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria,4FYJH@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_4784228_4	1123023.JIAI01000005_gene736	9.467e-69	239.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4DZAX@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
GDHHQS3_k127_4784228_2	644966.Tmar_1991	1.059e-100	340.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WCD3@538999|Clostridiales incertae sedis	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS3_k127_4784228_5	411473.RUMCAL_02721	5.929e-55	200.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS3_k127_4784228_0	243164.DET1188	8.597e-163	522.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2G63D@200795|Chloroflexi,34CNV@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GDHHQS3_k127_4784228_7	1382304.JNIL01000001_gene1648	6.052e-41	167.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,279P7@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
GDHHQS3_k127_4784228_10	136273.GY22_08120	3.237e-05	53.0	2BG4A@1|root,32A10@2|Bacteria,2HTN7@201174|Actinobacteria,1WBWP@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4784228_3	255470.cbdbA12	1.295e-97	336.0	COG0389@1|root,COG0389@2|Bacteria,2G6I6@200795|Chloroflexi,34CJ5@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS3_k127_4784228_9	479434.Sthe_1360	1.797e-28	123.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi,27YB6@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_4784228_1	266117.Rxyl_0748	1.982e-122	400.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_4784228_6	562970.Btus_0655	6.466e-47	177.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator (AsnC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
GDHHQS3_k127_4795517_3	1267535.KB906767_gene735	7.189e-70	250.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4795517_0	314278.NB231_10058	8.293e-110	361.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1WXFH@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
GDHHQS3_k127_4795517_1	285514.JNWO01000014_gene5699	1.242e-86	300.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GDHHQS3_k127_4795517_2	1089545.KB913037_gene6024	4.333e-78	266.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_4795517_4	471857.Svir_22780	8.703e-53	195.0	COG1028@1|root,COG1028@2|Bacteria,2GKZK@201174|Actinobacteria,4EASU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_4798089_2	429009.Adeg_0447	2.032e-42	162.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS3_k127_4798089_0	552811.Dehly_0366	2.249e-50	184.0	COG1246@1|root,COG1246@2|Bacteria,2G95D@200795|Chloroflexi,34CZ0@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GDHHQS3_k127_4798089_1	765420.OSCT_2853	7.406e-47	178.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi,375GI@32061|Chloroflexia	32061|Chloroflexia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS3_k127_4846543_4	553973.CLOHYLEM_07712	7.519e-18	90.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,22242@1506553|Lachnoclostridium	186801|Clostridia	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_4846543_3	1449357.JQLK01000001_gene707	2.231e-30	124.0	COG0316@1|root,COG0316@2|Bacteria,1WKA9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the HesB IscA family	hesB	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GDHHQS3_k127_4846543_6	113355.CM001775_gene2081	1.225e-09	62.0	COG1598@1|root,COG1598@2|Bacteria,1G9G2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_4846543_1	479434.Sthe_0984	6.451e-37	144.0	COG1673@1|root,COG1673@2|Bacteria,2G9JU@200795|Chloroflexi,27Y95@189775|Thermomicrobia	189775|Thermomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS3_k127_4846543_0	309801.trd_1049	1.596e-146	485.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS3_k127_4846543_7	1144275.COCOR_00554	2.618e-05	56.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
GDHHQS3_k127_4846543_2	195250.CM001776_gene2075	3.845e-31	130.0	COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GDHHQS3_k127_4846543_5	485913.Krac_2843	2.168e-10	68.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4867819_4	1463841.JOIR01000014_gene1302	3.044e-25	114.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS3_k127_4867819_0	903818.KI912268_gene1318	4.12e-185	592.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
GDHHQS3_k127_4867819_5	1382356.JQMP01000004_gene182	5.981e-11	72.0	COG5662@1|root,COG5662@2|Bacteria,2G96Y@200795|Chloroflexi,27YEM@189775|Thermomicrobia	189775|Thermomicrobia	K	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GDHHQS3_k127_4867819_3	1382356.JQMP01000003_gene1500	1.855e-41	160.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27Z8H@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4867819_2	357808.RoseRS_2469	2.498e-48	184.0	COG1404@1|root,COG1404@2|Bacteria,2G7GP@200795|Chloroflexi,375SG@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM LPXTG-motif cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS3_k127_4867819_6	324925.Ppha_0125	1.425e-10	65.0	2E8QS@1|root,3331S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4867819_1	543632.JOJL01000035_gene5071	1.304e-84	287.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_489398_4	1423814.HMPREF0549_0200	2.798e-05	48.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae	91061|Bacilli	L	ADP-ribose pyrophosphatase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
GDHHQS3_k127_489398_2	84531.JMTZ01000108_gene4274	2.419e-32	133.0	COG0537@1|root,COG0537@2|Bacteria,1N422@1224|Proteobacteria,1SFGR@1236|Gammaproteobacteria,1X7JR@135614|Xanthomonadales	135614|Xanthomonadales	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS3_k127_489398_1	1462527.CCDM010000001_gene2670	4.784e-81	289.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,23JE7@182709|Oceanobacillus	91061|Bacilli	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_489398_3	1120949.KB903316_gene33	5.324e-31	130.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4DCRN@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS3_k127_489398_0	871968.DESME_05950	1.851e-135	445.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,2600W@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GDHHQS3_k127_4918804_2	479434.Sthe_3414	1.886e-46	175.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2,UPF0158
GDHHQS3_k127_4918804_0	926550.CLDAP_22240	8.8e-116	392.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
GDHHQS3_k127_4918804_4	331113.SNE_A02330	1.832e-10	73.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
GDHHQS3_k127_4918804_1	1303518.CCALI_01268	1.714e-69	251.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4918804_3	477641.MODMU_0957	1.547e-42	164.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4ES81@85013|Frankiales	201174|Actinobacteria	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_4918804_5	118161.KB235922_gene360	8.506e-05	49.0	COG1216@1|root,COG1216@2|Bacteria,1GPV3@1117|Cyanobacteria,3VMF1@52604|Pleurocapsales	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_4921112_1	768706.Desor_0660	4.814e-70	249.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,260R6@186807|Peptococcaceae	186801|Clostridia	C	NADH dehydrogenase	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GDHHQS3_k127_4921112_0	552811.Dehly_0941	3.368e-93	318.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,34CWG@301297|Dehalococcoidia	301297|Dehalococcoidia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS3_k127_4921398_3	552811.Dehly_0196	4.747e-69	251.0	COG0750@1|root,COG0750@2|Bacteria,2G6HV@200795|Chloroflexi,34D8H@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GDHHQS3_k127_4921398_0	649747.HMPREF0083_02761	2.115e-108	364.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS3_k127_4921398_6	316274.Haur_3934	8.316e-36	149.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi,375K2@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS3_k127_4921398_1	1128421.JAGA01000003_gene3285	8.761e-92	309.0	COG0020@1|root,COG0020@2|Bacteria,2NP9M@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS3_k127_4921398_4	479434.Sthe_1737	7.96e-60	212.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi,27Y79@189775|Thermomicrobia	189775|Thermomicrobia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS3_k127_4921398_5	1382356.JQMP01000003_gene2247	9.61e-56	199.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi,27Y81@189775|Thermomicrobia	189775|Thermomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS3_k127_4921398_2	525904.Tter_1520	7.526e-90	307.0	COG0052@1|root,COG0052@2|Bacteria,2NP4M@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS3_k127_4921398_9	1382356.JQMP01000001_gene910	1.654e-05	53.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
GDHHQS3_k127_4921398_7	1444309.JAQG01000073_gene261	8.945e-21	107.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_4922152_0	744979.R2A130_1918	2.475e-34	133.0	COG3045@1|root,COG3045@2|Bacteria,1RDI5@1224|Proteobacteria,2VG9B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Crea protein	creA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05805	-	-	-	-	ko00000	-	-	-	CreA
GDHHQS3_k127_4922152_2	420324.KI911976_gene3156	1.979e-18	91.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria,1JUTG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS3_k127_4922152_3	1096546.WYO_4079	3.973e-13	77.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TV5E@28211|Alphaproteobacteria,1JSQX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_4989637_6	5762.XP_002671268.1	0.0006797	48.0	2D8YH@1|root,2S1SN@2759|Eukaryota	2759|Eukaryota	M	peptidoglycan catabolic process	-	GO:0000270,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016787,GO:0016798,GO:0030203,GO:0031410,GO:0031982,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0050830,GO:0050896,GO:0051704,GO:0051707,GO:0061783,GO:0071704,GO:0097708,GO:0098542,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
GDHHQS3_k127_4989637_3	525904.Tter_0503	2.342e-55	202.0	COG0500@1|root,COG2226@2|Bacteria,2NPGE@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS3_k127_4989637_2	335543.Sfum_2480	1.109e-55	203.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS3_k127_4989637_1	552811.Dehly_0977	1.286e-102	342.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34D04@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_4989637_0	479434.Sthe_1667	1.983e-165	530.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,27Y41@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS3_k127_4989637_4	751945.Theos_0127	2.539e-20	93.0	COG1598@1|root,COG1598@2|Bacteria,1WK5R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4989637_5	751945.Theos_0126	2.259e-18	86.0	COG1724@1|root,COG1724@2|Bacteria,1WKJQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_5025647_0	880073.Calab_2574	1.683e-259	813.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS3_k127_5025647_7	1121938.AUDY01000007_gene2501	2.676e-08	57.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5025647_6	1382356.JQMP01000001_gene1019	5.834e-28	127.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
GDHHQS3_k127_5025647_4	1382356.JQMP01000004_gene561	9.193e-80	276.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_5025647_1	2850.Phatr30967	8.4e-214	677.0	COG0059@1|root,2QQBF@2759|Eukaryota,2XBFP@2836|Bacillariophyta	2836|Bacillariophyta	EH	Acetohydroxy acid isomeroreductase, catalytic domain	-	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
GDHHQS3_k127_5025647_5	1306174.JODP01000032_gene4027	1.21e-79	293.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
GDHHQS3_k127_5025647_2	1382356.JQMP01000003_gene2120	4.525e-112	385.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
GDHHQS3_k127_5025647_3	926550.CLDAP_06490	3.805e-93	314.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_5026403_3	866895.HBHAL_1351	5.711e-14	74.0	COG1670@1|root,COG1670@2|Bacteria,1V74P@1239|Firmicutes,4HJ7B@91061|Bacilli,3NES5@45667|Halobacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_5026403_4	1123400.KB904749_gene774	1.467e-10	68.0	2EH3U@1|root,33AVT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5026403_0	351627.Csac_1956	1.456e-190	604.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
GDHHQS3_k127_5026403_2	1303518.CCALI_02177	2.356e-28	116.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7
GDHHQS3_k127_5026403_1	861299.J421_3809	6.873e-113	373.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS3_k127_5037946_1	309801.trd_A0640	2.095e-13	78.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_5037946_0	706587.Desti_0932	1.688e-120	403.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
GDHHQS3_k127_5047369_1	1121381.JNIV01000067_gene2293	8.822e-63	228.0	COG0412@1|root,COG0412@2|Bacteria,1WM88@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_5047369_0	1429916.X566_03940	6.416e-85	291.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR0N@28211|Alphaproteobacteria,3JUIB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_5132510_5	1206735.BAGG01000019_gene805	2.798e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4FVZ0@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_5132510_3	1111479.AXAR01000003_gene1515	8.833e-40	153.0	COG1853@1|root,COG1853@2|Bacteria,1V5M1@1239|Firmicutes,4HJWQ@91061|Bacilli	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
GDHHQS3_k127_5132510_2	1137271.AZUM01000006_gene461	3.588e-68	248.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4E0UW@85010|Pseudonocardiales	201174|Actinobacteria	EK	PFAM Aminotransferase class I and II	avtA	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GDHHQS3_k127_5132510_1	627192.SLG_07930	7.423e-142	464.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,2K0QE@204457|Sphingomonadales	204457|Sphingomonadales	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Peptidase_S9
GDHHQS3_k127_5132510_0	1379698.RBG1_1C00001G0798	2.013e-207	676.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
GDHHQS3_k127_514613_5	684949.ATTJ01000003_gene3119	1.164e-17	89.0	COG0477@1|root,COG2814@2|Bacteria,1WIGC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_514613_3	345341.KUTG_07033	2.136e-41	164.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4EEIC@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_514613_2	1449126.JQKL01000028_gene2582	7.351e-71	253.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,249R4@186801|Clostridia	186801|Clostridia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS3_k127_514613_0	1379698.RBG1_1C00001G1220	1.596e-113	383.0	COG0620@1|root,COG0620@2|Bacteria,2NPAE@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Meth_synt_1,Meth_synt_2
GDHHQS3_k127_514613_1	309799.DICTH_1645	7.005e-77	271.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
GDHHQS3_k127_514613_4	272562.CA_C2230	3.016e-21	105.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,36FMJ@31979|Clostridiaceae	186801|Clostridia	M	PFAM Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GDHHQS3_k127_516285_1	479434.Sthe_1634	2.082e-35	144.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,27YBK@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_516285_2	357808.RoseRS_0164	2.006e-17	94.0	COG1051@1|root,COG1051@2|Bacteria,2G9EQ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_516285_0	1121861.KB899922_gene3171	2.056e-72	263.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2JQAP@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS3_k127_516285_3	1408224.SAMCCGM7_c4674	1.004e-15	79.0	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2UD2U@28211|Alphaproteobacteria,4BKYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
GDHHQS3_k127_518382_2	762983.HMPREF9444_00688	3.326e-87	297.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1Y43D@135624|Aeromonadales	135624|Aeromonadales	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_518382_4	330214.NIDE3680	9.398e-51	193.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
GDHHQS3_k127_518382_3	926554.KI912633_gene3829	6.495e-76	261.0	COG0066@1|root,COG0066@2|Bacteria,1WIK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GDHHQS3_k127_518382_0	525904.Tter_0194	4.662e-216	678.0	COG0065@1|root,COG0065@2|Bacteria,2NP2K@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700	Aconitase
GDHHQS3_k127_518382_5	643648.Slip_0214	3.202e-24	110.0	COG1848@1|root,COG1848@2|Bacteria,1U5UN@1239|Firmicutes,25P95@186801|Clostridia,42KUD@68298|Syntrophomonadaceae	186801|Clostridia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_518382_6	264732.Moth_0253	1.133e-09	64.0	COG2002@1|root,COG2002@2|Bacteria,1VGCT@1239|Firmicutes,24UBR@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_518382_1	255470.cbdbA808	4.266e-180	574.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,34CY8@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_5191156_0	196490.AUEZ01000058_gene1085	2.933e-129	432.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
GDHHQS3_k127_5194729_0	868595.Desca_1100	2.247e-140	458.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS3_k127_5194729_2	926569.ANT_16040	1.147e-23	107.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS3_k127_5194729_3	1235799.C818_02753	1.844e-18	87.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,27PPC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	KH domain	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS3_k127_5194729_1	525904.Tter_1632	6.52e-33	136.0	COG0806@1|root,COG0806@2|Bacteria,2NPUX@2323|unclassified Bacteria	2|Bacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_5194729_4	243164.DET1552	0.000159	53.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_5229887_1	91464.S7335_2847	1.776e-19	91.0	COG0644@1|root,COG0644@2|Bacteria,1G117@1117|Cyanobacteria,1GYJZ@1129|Synechococcus	1117|Cyanobacteria	C	COG0644 Dehydrogenases (flavoproteins)	fixC	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_3,NAD_binding_8,Pyr_redox_2,Trp_halogenase
GDHHQS3_k127_5229887_2	383372.Rcas_1530	8.131e-15	87.0	2EQGV@1|root,33I2V@2|Bacteria,2G7HG@200795|Chloroflexi,375SC@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
GDHHQS3_k127_5229887_0	243164.DET0009	1.679e-117	387.0	COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi,34CQR@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_5229887_3	1165096.ARWF01000001_gene1395	3.76e-06	54.0	2C4GY@1|root,34053@2|Bacteria,1NYQV@1224|Proteobacteria	1224|Proteobacteria	S	Family of unknown function (DUF5343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5343
GDHHQS3_k127_5241585_0	1210884.HG799466_gene13018	2.923e-80	276.0	COG1230@1|root,COG1230@2|Bacteria,2J098@203682|Planctomycetes	203682|Planctomycetes	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS3_k127_5241585_3	485913.Krac_9989	9.708e-31	125.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS3_k127_5241585_2	765420.OSCT_1793	3.262e-45	177.0	COG0526@1|root,COG0526@2|Bacteria,2GACV@200795|Chloroflexi,375FU@32061|Chloroflexia	32061|Chloroflexia	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
GDHHQS3_k127_5241585_1	485913.Krac_5268	3.674e-48	179.0	COG1011@1|root,COG1011@2|Bacteria,2G8TC@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS3_k127_5255748_4	671143.DAMO_1028	4.522e-47	173.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
GDHHQS3_k127_5255748_1	222534.KB893765_gene2920	7.742e-104	346.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	mmsB2	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_5255748_0	479434.Sthe_1794	2.69e-156	501.0	COG1960@1|root,COG1960@2|Bacteria,2G815@200795|Chloroflexi,27Z4U@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_5255748_3	42256.RradSPS_1705	6.505e-54	194.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CQDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GDHHQS3_k127_5255748_2	1040989.AWZU01000048_gene1487	1.523e-97	323.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,3JS92@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	MA20_16525	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS3_k127_5258366_1	91464.S7335_1916	3.328e-18	94.0	COG2340@1|root,COG2931@1|root,COG2340@2|Bacteria,COG2931@2|Bacteria,1G4UZ@1117|Cyanobacteria,1H1QM@1129|Synechococcus	1117|Cyanobacteria	Q	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HemolysinCabind
GDHHQS3_k127_5258366_0	479434.Sthe_1776	5.171e-70	247.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GDHHQS3_k127_5295222_1	1122917.KB899675_gene235	1.721e-43	164.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,26RBB@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_5295222_0	926550.CLDAP_22950	2.809e-94	319.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
GDHHQS3_k127_5295222_2	1122221.JHVI01000017_gene2085	1.449e-24	106.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
GDHHQS3_k127_5295222_3	118163.Ple7327_1864	6.177e-19	91.0	COG0352@1|root,COG0352@2|Bacteria,1G1VB@1117|Cyanobacteria,3VIC1@52604|Pleurocapsales	1117|Cyanobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.thiE	TMP-TENI
GDHHQS3_k127_5318105_0	671143.DAMO_0754	8.553e-144	473.0	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS3_k127_5318105_4	479434.Sthe_3125	3.921e-66	244.0	COG0477@1|root,COG2814@2|Bacteria,2G6HS@200795|Chloroflexi,27XYB@189775|Thermomicrobia	189775|Thermomicrobia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_5318105_1	1382306.JNIM01000001_gene4091	1.34e-109	376.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS3_k127_5318105_2	504728.K649_12300	1.664e-80	276.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS3_k127_5318105_3	309801.trd_1166	8.446e-77	275.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia	189775|Thermomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS3_k127_532031_1	311424.DhcVS_292	4.863e-13	74.0	2A3TQ@1|root,30SBK@2|Bacteria,2G9W9@200795|Chloroflexi,34DJK@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_532031_0	311424.DhcVS_293	4.073e-135	444.0	COG3567@1|root,COG3567@2|Bacteria,2G7F0@200795|Chloroflexi,34DDN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
GDHHQS3_k127_532031_2	311424.DhcVS_293	1.189e-10	66.0	COG3567@1|root,COG3567@2|Bacteria,2G7F0@200795|Chloroflexi,34DDN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
GDHHQS3_k127_532031_3	760011.Spico_0899	6.709e-07	55.0	COG1022@1|root,COG1022@2|Bacteria,2J65F@203691|Spirochaetes	203691|Spirochaetes	I	Long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_5333801_1	1382359.JIAL01000001_gene2229	4.103e-56	207.0	COG0477@1|root,COG0477@2|Bacteria,3Y2GP@57723|Acidobacteria,2JIJ5@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_5333801_0	1183438.GKIL_3357	2.734e-80	284.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
GDHHQS3_k127_5333801_2	269799.Gmet_1207	2.404e-21	98.0	2DUF0@1|root,33QC9@2|Bacteria,1NU5F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5349966_1	555088.DealDRAFT_1545	9.671e-62	222.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,42JTN@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GDHHQS3_k127_5349966_4	309801.trd_1809	3.713e-19	93.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_5349966_2	552811.Dehly_1102	2.672e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,34D3G@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
GDHHQS3_k127_5349966_0	561175.KB894093_gene3230	1.903e-65	237.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4EFQ0@85012|Streptosporangiales	201174|Actinobacteria	M	GDP-mannose 4,6 dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_5349966_3	314285.KT71_09467	3.342e-26	121.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1MVRF@1224|Proteobacteria,1RWT8@1236|Gammaproteobacteria,1JASF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD
GDHHQS3_k127_5350515_5	316274.Haur_2566	3.356e-07	59.0	COG1286@1|root,COG1286@2|Bacteria,2G9GY@200795|Chloroflexi,3762H@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
GDHHQS3_k127_5350515_1	1173026.Glo7428_1230	1.038e-82	282.0	COG1691@1|root,COG1691@2|Bacteria,1G1W3@1117|Cyanobacteria	1117|Cyanobacteria	S	COG1691 NCAIR mutase (PurE)-related	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GDHHQS3_k127_5350515_0	383372.Rcas_1165	1.018e-101	344.0	COG1641@1|root,COG1641@2|Bacteria,2G5MP@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GDHHQS3_k127_5350515_2	1120972.AUMH01000001_gene1163	8.109e-46	176.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli	91061|Bacilli	K	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_5350515_3	743721.Psesu_1933	1.751e-38	152.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GDHHQS3_k127_5350515_4	1292034.OR37_03680	2.221e-17	89.0	2DPVY@1|root,333MG@2|Bacteria,1NPT0@1224|Proteobacteria,2UKR4@28211|Alphaproteobacteria,2KHI2@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
GDHHQS3_k127_5405165_1	1336243.JAEA01000006_gene402	1.025e-77	269.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2U1X2@28211|Alphaproteobacteria,1JXV3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
GDHHQS3_k127_5405165_0	1172188.KB911826_gene159	9.892e-233	735.0	COG2838@1|root,COG2838@2|Bacteria,2GJ1C@201174|Actinobacteria,4FFA1@85021|Intrasporangiaceae	201174|Actinobacteria	C	NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
GDHHQS3_k127_541883_0	1248760.ANFZ01000007_gene2867	8.979e-140	452.0	COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2U4H1@28211|Alphaproteobacteria,2K3XM@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
GDHHQS3_k127_541883_3	565045.NOR51B_2416	9.76e-06	59.0	COG1240@1|root,COG1240@2|Bacteria,1R4IW@1224|Proteobacteria,1SN40@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_541883_1	1122917.KB899674_gene312	3.908e-67	236.0	COG1335@1|root,COG1335@2|Bacteria,1VA32@1239|Firmicutes,4HKVT@91061|Bacilli,26XP2@186822|Paenibacillaceae	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS3_k127_541883_2	1122917.KB899674_gene313	1.66e-24	108.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_5440500_0	2903.EOD40718	1.417e-58	212.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
GDHHQS3_k127_5440500_1	765420.OSCT_3073	1.497e-43	170.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,375HJ@32061|Chloroflexia	32061|Chloroflexia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS3_k127_5440500_2	479432.Sros_7943	2.104e-08	63.0	2C5NN@1|root,2ZJPF@2|Bacteria,2GV7Y@201174|Actinobacteria,4EKGV@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5465075_8	521011.Mpal_1285	3.118e-13	82.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,GSDH
GDHHQS3_k127_5465075_7	644966.Tmar_0323	6.667e-25	117.0	COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia	186801|Clostridia	C	PFAM Rieske 2Fe-2S domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS3_k127_5465075_6	292459.STH3147	1.291e-33	144.0	COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia	186801|Clostridia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
GDHHQS3_k127_5465075_3	1382306.JNIM01000001_gene1047	7.931e-94	314.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
GDHHQS3_k127_5465075_4	477641.MODMU_1201	8.624e-70	243.0	COG1215@1|root,COG2246@1|root,COG1215@2|Bacteria,COG2246@2|Bacteria,2GJTE@201174|Actinobacteria,4ES8M@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
GDHHQS3_k127_5465075_5	489825.LYNGBM3L_21480	1.5e-38	148.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HGCH@1150|Oscillatoriales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_5465075_0	552811.Dehly_1425	5.401e-178	571.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,34CRG@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS3_k127_5465075_2	1071679.BG57_20865	1.349e-94	321.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_5465075_1	552811.Dehly_0397	3.233e-140	456.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,34CJ3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
GDHHQS3_k127_5467468_7	760568.Desku_1695	5.706e-78	267.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
GDHHQS3_k127_5467468_0	479434.Sthe_1293	1.129e-149	484.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS3_k127_5467468_1	471852.Tcur_2962	7.934e-148	483.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EI99@85012|Streptosporangiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GDHHQS3_k127_5467468_4	479434.Sthe_1292	3.775e-110	367.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS3_k127_5467468_9	479434.Sthe_1291	1.336e-21	99.0	COG1828@1|root,COG1828@2|Bacteria,2GBWK@200795|Chloroflexi,27YN2@189775|Thermomicrobia	189775|Thermomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
GDHHQS3_k127_5467468_8	357808.RoseRS_1120	2.541e-64	225.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,375HN@32061|Chloroflexia	32061|Chloroflexia	E	PFAM imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
GDHHQS3_k127_5467468_3	1521187.JPIM01000066_gene2678	3.503e-114	381.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,37543@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_5467468_2	479434.Sthe_1676	6.489e-127	421.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,27XKM@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
GDHHQS3_k127_5467468_5	1123242.JH636434_gene3342	2.277e-108	359.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
GDHHQS3_k127_5467468_6	479434.Sthe_1855	2.141e-96	334.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
GDHHQS3_k127_5467468_11	1211815.CBYP010000021_gene3300	3.472e-12	76.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4ETJ6@85013|Frankiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_5467468_10	1123250.KB908380_gene805	1.858e-15	79.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4H1W3@909932|Negativicutes	909932|Negativicutes	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
GDHHQS3_k127_5532479_0	886293.Sinac_0625	1.514e-146	480.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	2|Bacteria	S	PFAM Peptidase M16 inactive domain	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_5532479_6	644966.Tmar_1104	6.646e-29	120.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GDHHQS3_k127_5532479_3	671143.DAMO_1028	6.182e-121	395.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
GDHHQS3_k127_5532479_7	390989.JOEG01000023_gene5829	1.468e-21	96.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4DE3Z@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_5532479_1	671143.DAMO_1024	6.295e-140	454.0	COG0476@1|root,COG1977@1|root,COG0476@2|Bacteria,COG1977@2|Bacteria,2NPX3@2323|unclassified Bacteria	2|Bacteria	H	ThiF family	moeB	-	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
GDHHQS3_k127_5532479_2	671143.DAMO_1023	2.444e-131	425.0	COG0031@1|root,COG0031@2|Bacteria,2NNTU@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK-1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_5532479_5	485913.Krac_12539	1.439e-41	157.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS3_k127_5532479_4	1128421.JAGA01000003_gene3188	5.578e-71	253.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	-	-	-	ko:K03324,ko:K03466	-	-	-	-	ko00000,ko02000,ko03036	2.A.58.2,3.A.12	-	-	Na_Pi_cotrans,PHO4,PhoU
GDHHQS3_k127_5552437_1	1454004.AW11_01770	3.786e-157	508.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,1KQAZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	MmgE/PrpD family	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GDHHQS3_k127_5552437_4	1125863.JAFN01000001_gene1505	1.412e-49	188.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2WPAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_5552437_3	388413.ALPR1_14479	4.668e-103	350.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
GDHHQS3_k127_5552437_2	1121468.AUBR01000001_gene581	7.626e-113	376.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,42EU4@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS3_k127_5552437_0	357808.RoseRS_3006	4.882e-185	600.0	COG0714@1|root,COG1067@1|root,COG0714@2|Bacteria,COG1067@2|Bacteria,2G64R@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
GDHHQS3_k127_5592001_3	322710.Avin_40470	3.347e-09	62.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Preprotein translocase	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS3_k127_5592001_0	255470.cbdbA274	5.902e-86	303.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,34CQF@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
GDHHQS3_k127_5592001_1	1382356.JQMP01000003_gene2165	1.364e-64	233.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_5592001_2	349163.Acry_1268	3.183e-63	226.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,2JS6T@204441|Rhodospirillales	204441|Rhodospirillales	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GDHHQS3_k127_5600075_1	479434.Sthe_0699	8.879e-85	287.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GDHHQS3_k127_5600075_0	649747.HMPREF0083_03606	1.626e-109	361.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,26RKF@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22430	Pantoate_transf
GDHHQS3_k127_5600075_3	479434.Sthe_0697	6.23e-59	215.0	COG5495@1|root,COG5495@2|Bacteria,2G6F3@200795|Chloroflexi,27YA4@189775|Thermomicrobia	189775|Thermomicrobia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GDHHQS3_k127_5600075_4	1123508.JH636441_gene3648	1.067e-30	130.0	COG0546@1|root,COG0546@2|Bacteria,2IZQM@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2
GDHHQS3_k127_5600075_5	671143.DAMO_1510	8.82e-23	103.0	COG0607@1|root,COG0607@2|Bacteria,2NRI8@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_5600075_2	525904.Tter_1201	5.772e-64	224.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_5603716_2	330214.NIDE1819	3.439e-100	332.0	COG0498@1|root,COG0498@2|Bacteria,3J0FZ@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_5603716_8	1162668.LFE_1737	4.135e-19	93.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
GDHHQS3_k127_5603716_6	864702.OsccyDRAFT_2993	3.381e-31	126.0	COG1977@1|root,COG1977@2|Bacteria,1G86C@1117|Cyanobacteria,1HC6T@1150|Oscillatoriales	1117|Cyanobacteria	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_5603716_10	477974.Daud_2115	1.963e-13	76.0	COG1598@1|root,COG1598@2|Bacteria,1VHA0@1239|Firmicutes,24TBV@186801|Clostridia,26315@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_5603716_9	767817.Desgi_3653	5.068e-17	83.0	COG1724@1|root,COG1724@2|Bacteria,1VKXG@1239|Firmicutes,24UW1@186801|Clostridia	186801|Clostridia	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_5603716_7	1121378.KB899696_gene2698	2.459e-25	112.0	COG0563@1|root,COG0563@2|Bacteria,1WMN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5603716_1	1121472.AQWN01000002_gene2159	9.756e-121	398.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_5603716_4	1382306.JNIM01000001_gene442	4.546e-59	216.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS3_k127_5603716_5	869210.Marky_2009	2.78e-41	167.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1WJ1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS3_k127_5603716_0	1128421.JAGA01000002_gene222	4.428e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_5603716_3	479434.Sthe_1589	2.32e-93	320.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,27XZ3@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_5607388_0	326427.Cagg_3777	1.741e-267	839.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS3_k127_5649002_1	331869.BAL199_17848	2.77e-53	197.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TUUN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate	-	-	4.1.1.3	ko:K01003	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
GDHHQS3_k127_5649002_0	401526.TcarDRAFT_0930	1.062e-69	255.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H3GM@909932|Negativicutes	909932|Negativicutes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS3_k127_5649002_2	767817.Desgi_0154	4.446e-05	49.0	COG2919@1|root,COG2919@2|Bacteria,1VGDD@1239|Firmicutes,25PD5@186801|Clostridia,26308@186807|Peptococcaceae	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
GDHHQS3_k127_5653742_2	485913.Krac_9942	3.61e-06	53.0	COG1011@1|root,COG1011@2|Bacteria,2G73G@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
GDHHQS3_k127_5653742_3	554065.XP_005848121.1	0.0007487	45.0	COG1011@1|root,KOG3085@2759|Eukaryota,37V2M@33090|Viridiplantae,34M4C@3041|Chlorophyta	3041|Chlorophyta	S	HAD-hyrolase-like	-	-	3.1.3.29	ko:K01097	ko00520,ko01100,map00520,map01100	-	R01805	RC00017	ko00000,ko00001,ko01000,ko01009	-	-	-	HAD_2
GDHHQS3_k127_5653742_1	926550.CLDAP_29850	1.929e-35	146.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS3_k127_5653742_0	85643.Tmz1t_1565	1.499e-121	396.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS3_k127_5666222_3	552811.Dehly_1035	1.539e-37	149.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,34D5F@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS3_k127_5666222_10	880073.Calab_3411	6.543e-08	57.0	COG1598@1|root,COG1598@2|Bacteria,2NQ8D@2323|unclassified Bacteria	2|Bacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_5666222_9	391612.CY0110_10097	3.088e-12	69.0	COG1724@1|root,COG1724@2|Bacteria,1GA91@1117|Cyanobacteria,3KK77@43988|Cyanothece	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_5666222_4	742766.HMPREF9455_04119	1.248e-27	115.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,2FTGA@200643|Bacteroidia,22Y50@171551|Porphyromonadaceae	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS3_k127_5666222_2	562970.Btus_3230	1.119e-54	201.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4HACH@91061|Bacilli,277Y1@186823|Alicyclobacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_5666222_5	1123371.ATXH01000017_gene661	7.058e-26	120.0	COG0852@1|root,COG0852@2|Bacteria,2GHXK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS3_k127_5666222_0	886293.Sinac_5547	1.235e-112	377.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,2IYN8@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_5666222_1	255470.cbdbA879	4.807e-77	274.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi,34CTC@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_5666222_8	926550.CLDAP_35220	1.273e-19	97.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS3_k127_5666222_6	479433.Caci_0850	7.433e-26	113.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_5666222_7	292564.Cyagr_2876	9.24e-25	106.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,22SWX@167375|Cyanobium	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
GDHHQS3_k127_5689781_0	552811.Dehly_1077	5.471e-113	376.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,34CNS@301297|Dehalococcoidia	301297|Dehalococcoidia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS3_k127_5689781_2	693661.Arcve_1092	6.15e-70	243.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GDHHQS3_k127_5689781_1	562970.Btus_0175	9.518e-85	288.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_5689781_6	457570.Nther_0218	1.197e-29	120.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS3_k127_5689781_7	204669.Acid345_1250	2.511e-11	64.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria,2JK4W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS3_k127_5689781_5	1382306.JNIM01000001_gene3524	1.756e-46	171.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS3_k127_5689781_4	485913.Krac_12503	2.911e-57	201.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS3_k127_5689781_3	1069080.KB913028_gene496	7.498e-61	214.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4H3YU@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS3_k127_5693088_1	383372.Rcas_0601	1.384e-109	372.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,3753C@32061|Chloroflexia	32061|Chloroflexia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS3_k127_5693088_5	525904.Tter_1653	1.426e-16	81.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
GDHHQS3_k127_5693088_2	1161401.ASJA01000013_gene668	1.664e-67	237.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,43X2T@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_5693088_4	153948.NAL212_0962	1.118e-19	99.0	COG2304@1|root,COG2304@2|Bacteria,1PE8B@1224|Proteobacteria,2WC99@28216|Betaproteobacteria,374H0@32003|Nitrosomonadales	28216|Betaproteobacteria	S	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
GDHHQS3_k127_5693088_0	255470.cbdbA1185	2.365e-157	510.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,34D3N@301297|Dehalococcoidia	301297|Dehalococcoidia	E	arginine biosynthetic process via ornithine	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS3_k127_5693088_3	1146883.BLASA_3367	3.977e-50	184.0	COG0662@1|root,COG0662@2|Bacteria,2IH8K@201174|Actinobacteria,4EWGP@85013|Frankiales	201174|Actinobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_5693088_6	1044.EH31_03560	6.226e-10	62.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,2K0AN@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS3_k127_569935_1	234267.Acid_1032	1.792e-32	139.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
GDHHQS3_k127_569935_0	234267.Acid_7331	3.467e-138	447.0	COG0470@1|root,COG0470@2|Bacteria,3Y6V7@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS3_k127_569935_2	596151.DesfrDRAFT_3654	2.557e-05	46.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS3_k127_5703513_3	926550.CLDAP_06490	7.548e-63	220.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_5703513_9	1384054.N790_14845	7.096e-07	59.0	COG0500@1|root,COG2226@2|Bacteria,1N7M1@1224|Proteobacteria,1SCU6@1236|Gammaproteobacteria,1X9AG@135614|Xanthomonadales	135614|Xanthomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_5703513_6	1254432.SCE1572_13735	6.802e-34	138.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.180	ko:K18846	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_5703513_4	525903.Taci_1370	9.075e-61	220.0	COG2301@1|root,COG2301@2|Bacteria,3T9UG@508458|Synergistetes	508458|Synergistetes	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
GDHHQS3_k127_5703513_10	1192759.AKIB01000056_gene1479	6.674e-06	55.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	mgrA	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS3_k127_5703513_0	311424.DhcVS_849	2.671e-140	457.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi,34D3D@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS3_k127_5703513_5	32264.tetur05g08380.1	2.535e-45	175.0	COG3663@1|root,KOG4120@2759|Eukaryota,38C6W@33154|Opisthokonta,3BFC3@33208|Metazoa,3D1WB@33213|Bilateria,41UUU@6656|Arthropoda	33208|Metazoa	L	It is involved in the biological process described with DNA repair	TDG	GO:0000122,GO:0000166,GO:0000287,GO:0000700,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003712,GO:0003824,GO:0004844,GO:0005080,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005886,GO:0006139,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006298,GO:0006304,GO:0006355,GO:0006357,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008263,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0017076,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0030554,GO:0030983,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031402,GO:0031404,GO:0031420,GO:0031974,GO:0031981,GO:0032091,GO:0032182,GO:0032183,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035510,GO:0035511,GO:0035561,GO:0035562,GO:0035639,GO:0036094,GO:0040029,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043412,GO:0043621,GO:0043739,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044728,GO:0045008,GO:0045892,GO:0045934,GO:0045995,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051239,GO:0051252,GO:0051253,GO:0051336,GO:0051716,GO:0055086,GO:0055114,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070988,GO:0070989,GO:0071704,GO:0071944,GO:0072527,GO:0072529,GO:0080090,GO:0080111,GO:0090304,GO:0097159,GO:0097367,GO:0097506,GO:0140097,GO:0140110,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902544,GO:1902679,GO:1903506,GO:1903507,GO:2000026,GO:2000112,GO:2000113,GO:2001141	3.2.2.29	ko:K20813	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_5703513_2	311424.DhcVS_846	1.106e-92	313.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,34CY7@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS3_k127_5703513_1	311424.DhcVS_845	2.781e-111	389.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,34CM5@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_5703513_7	479434.Sthe_0124	9.75e-34	145.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,27YS9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5703513_8	1297570.MESS4_30021	5.643e-08	58.0	COG2079@1|root,COG2079@2|Bacteria,1R9ER@1224|Proteobacteria,2U4QI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GDHHQS3_k127_5712987_0	1125863.JAFN01000001_gene1417	1.492e-174	556.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS3_k127_5712987_2	682795.AciX8_2476	0.0002323	52.0	2DT0H@1|root,33I61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5712987_1	502025.Hoch_3343	1.599e-113	381.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria,2YUME@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent proteases and their inactivated homologs	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_5723128_1	1382306.JNIM01000001_gene4215	1.027e-27	126.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS3_k127_5723128_0	1120973.AQXL01000122_gene189	1.83e-58	209.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_5749932_6	1146883.BLASA_2799	2.03e-24	110.0	COG1063@1|root,COG1063@2|Bacteria,2GP97@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_5749932_0	1382306.JNIM01000001_gene2607	6.177e-138	449.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_5749932_3	1449126.JQKL01000022_gene118	5.97e-62	221.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,24GH5@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_5749932_7	525904.Tter_0280	2.258e-18	90.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
GDHHQS3_k127_5749932_5	1162668.LFE_1999	2.135e-39	153.0	COG3748@1|root,COG3748@2|Bacteria,3J19B@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:DUF989	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
GDHHQS3_k127_5749932_2	671143.DAMO_2625	3.444e-86	294.0	COG1210@1|root,COG1210@2|Bacteria,2NNV4@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_5749932_1	671143.DAMO_2491	6.873e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria	2|Bacteria	IQ	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_5749932_4	710686.Mycsm_02767	5.057e-41	157.0	COG4420@1|root,COG4420@2|Bacteria,2INCC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GDHHQS3_k127_5786913_0	552811.Dehly_0551	7.713e-217	681.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,34D3I@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS3_k127_5786913_2	525904.Tter_0062	4.814e-32	130.0	COG0355@1|root,COG0355@2|Bacteria,2NPSQ@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
GDHHQS3_k127_5786913_1	1120950.KB892750_gene6911	1.033e-43	164.0	COG0703@1|root,COG0703@2|Bacteria,2IHXC@201174|Actinobacteria,4DRQW@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5795734_3	479434.Sthe_1803	4.207e-50	187.0	COG1587@1|root,COG1587@2|Bacteria,2GBWA@200795|Chloroflexi,27Z62@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
GDHHQS3_k127_5795734_4	1357272.AVEO02000144_gene1770	3.521e-34	137.0	COG0494@1|root,COG0494@2|Bacteria,1QW0D@1224|Proteobacteria,1T2Q2@1236|Gammaproteobacteria,1Z9ZT@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_5795734_1	264462.Bd1631	6.44e-68	239.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS3_k127_5795734_0	1382356.JQMP01000001_gene828	1.519e-136	444.0	COG0113@1|root,COG0113@2|Bacteria,2G5QT@200795|Chloroflexi,27XTX@189775|Thermomicrobia	189775|Thermomicrobia	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
GDHHQS3_k127_5795734_2	1192034.CAP_2249	3.042e-60	224.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WV45@28221|Deltaproteobacteria,2YZDV@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GDHHQS3_k127_5799256_0	479434.Sthe_1621	0.0	1303.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
GDHHQS3_k127_5799256_2	504728.K649_10275	3.781e-10	69.0	COG1943@1|root,COG1943@2|Bacteria,1WKUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5799256_1	1123023.JIAI01000003_gene3164	9.15e-27	113.0	COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4E0T9@85010|Pseudonocardiales	201174|Actinobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
GDHHQS3_k127_5820516_2	479434.Sthe_2402	1.04e-11	74.0	COG2834@1|root,COG2834@2|Bacteria,2GBFM@200795|Chloroflexi,27ZBH@189775|Thermomicrobia	189775|Thermomicrobia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5820516_0	1121468.AUBR01000012_gene2572	3.717e-63	229.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
GDHHQS3_k127_5820516_1	1385521.N803_12975	2.15e-46	172.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4FG24@85021|Intrasporangiaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS3_k127_58462_2	257310.BB0728	1.645e-89	307.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2VQ87@28216|Betaproteobacteria,3T2ZG@506|Alcaligenaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	hcaE	-	1.14.12.11,1.14.12.19,1.14.12.3	ko:K03268,ko:K05708	ko00360,ko00361,ko00362,ko00623,ko00625,ko01100,ko01120,ko01220,map00360,map00361,map00362,map00623,map00625,map01100,map01120,map01220	M00545,M00547	R03543,R03559,R05429,R06782,R06783,R06831,R06856,R09151,R09152	RC00098,RC00267,RC00951,RC03011,RC03012,RC03013	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_58462_3	479434.Sthe_3318	2.383e-50	191.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	rbn	-	-	ko:K03466,ko:K07058	-	-	-	-	ko00000,ko03036	3.A.12	-	-	Virul_fac_BrkB
GDHHQS3_k127_58462_0	1382356.JQMP01000001_gene821	8.244e-243	776.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,27YY6@189775|Thermomicrobia	189775|Thermomicrobia	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS3_k127_58462_4	1385520.N802_03590	7.636e-14	78.0	arCOG05230@1|root,33GXI@2|Bacteria,2ICB0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_58462_1	1122915.AUGY01000118_gene6538	9.666e-98	327.0	COG4638@1|root,COG4638@2|Bacteria,1UZWG@1239|Firmicutes,4HBGQ@91061|Bacilli,26VC1@186822|Paenibacillaceae	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_5866738_3	479434.Sthe_1208	1.606e-73	257.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS3_k127_5866738_4	1382356.JQMP01000004_gene410	4.223e-27	120.0	2DHVB@1|root,3012B@2|Bacteria,2GB5E@200795|Chloroflexi,27ZBK@189775|Thermomicrobia	189775|Thermomicrobia	S	LppX_LprAFG lipoprotein	-	-	-	ko:K14954	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
GDHHQS3_k127_5866738_2	1380390.JIAT01000009_gene671	2.77e-74	268.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5866738_1	479434.Sthe_0512	5.995e-75	263.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi,27XG9@189775|Thermomicrobia	189775|Thermomicrobia	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GDHHQS3_k127_5866738_5	386456.JQKN01000020_gene1335	0.0005108	52.0	COG5440@1|root,arCOG01713@2157|Archaea,2XYFI@28890|Euryarchaeota,23PQ7@183925|Methanobacteria	183925|Methanobacteria	S	Uncharacterized conserved protein (DUF2299)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2299
GDHHQS3_k127_5866738_0	479434.Sthe_2294	1.486e-227	725.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
GDHHQS3_k127_5867549_1	479434.Sthe_1775	5.293e-92	308.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5867549_0	479434.Sthe_1776	4.126e-113	394.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GDHHQS3_k127_5880705_0	671143.DAMO_0259	2.451e-82	283.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS3_k127_5880705_1	1123024.AUII01000012_gene4230	2.158e-14	87.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4E2EW@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS3_k127_5945520_2	221288.JH992901_gene5374	4.169e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,1GJ57@1117|Cyanobacteria,1JHMN@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_5945520_0	502025.Hoch_6684	0.0	1168.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2YU96@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_5945520_3	216142.LT40_16590	1.81e-56	201.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551	AIRC
GDHHQS3_k127_5945520_1	42256.RradSPS_1262	3.69e-95	321.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily. LDH family	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS3_k127_5945520_4	1280692.AUJL01000002_gene2782	2.795e-32	134.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,36DM3@31979|Clostridiaceae	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
GDHHQS3_k127_5974319_3	1265505.ATUG01000002_gene2706	3.5e-19	90.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,42P8Y@68525|delta/epsilon subdivisions,2WJYW@28221|Deltaproteobacteria,2MIZ7@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
GDHHQS3_k127_5974319_1	391625.PPSIR1_24659	4.776e-46	186.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5974319_0	1128421.JAGA01000002_gene1145	8.737e-63	226.0	COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	menA	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737	UbiA
GDHHQS3_k127_5974319_2	1128421.JAGA01000003_gene2742	3.88e-31	125.0	COG1309@1|root,COG1309@2|Bacteria,2NRTD@2323|unclassified Bacteria	2|Bacteria	K	YsiA-like protein, C-terminal region	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TetR_C_4,TetR_N
GDHHQS3_k127_5974426_1	311424.DhcVS_295	4.874e-55	198.0	2DBIJ@1|root,2Z9G2@2|Bacteria,2G896@200795|Chloroflexi,34DN7@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
GDHHQS3_k127_5974426_2	1382356.JQMP01000004_gene582	6.689e-22	102.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi,27YC8@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
GDHHQS3_k127_5974426_0	243231.GSU0567	1.431e-74	256.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS3_k127_5974426_3	1122138.AQUZ01000004_gene994	4.712e-07	60.0	2EXUT@1|root,33R41@2|Bacteria,2I3GV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6001443_16	1380380.JIAX01000008_gene1870	1.261e-06	59.0	COG5661@1|root,COG5661@2|Bacteria,1NKYM@1224|Proteobacteria,2UEQB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
GDHHQS3_k127_6001443_3	311424.DhcVS_976	3.721e-58	207.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,34CZB@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_6001443_5	479434.Sthe_1245	8.687e-48	183.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,27Y6Z@189775|Thermomicrobia	189775|Thermomicrobia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS3_k127_6001443_2	309801.trd_0095	4.55e-71	250.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi,27XFH@189775|Thermomicrobia	189775|Thermomicrobia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
GDHHQS3_k127_6001443_4	255470.cbdbA32	1.095e-57	211.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,34CKI@301297|Dehalococcoidia	301297|Dehalococcoidia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_6001443_9	552811.Dehly_1508	1.989e-35	145.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,34DCB@301297|Dehalococcoidia	301297|Dehalococcoidia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
GDHHQS3_k127_6001443_13	525904.Tter_1706	1.046e-18	91.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_6001443_8	1382306.JNIM01000001_gene2680	3.916e-37	147.0	COG0720@1|root,COG0720@2|Bacteria,2G919@200795|Chloroflexi	200795|Chloroflexi	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_6001443_15	243230.DR_0057	3.148e-09	62.0	COG0695@1|root,COG0695@2|Bacteria,1WKQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
GDHHQS3_k127_6001443_12	309801.trd_A0787	2.761e-27	122.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_6001443_6	1125718.HMPREF1318_1558	1.754e-41	173.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4D3U7@85005|Actinomycetales	201174|Actinobacteria	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
GDHHQS3_k127_6001443_10	997346.HMPREF9374_1056	2.641e-31	134.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,27C3S@186824|Thermoactinomycetaceae	91061|Bacilli	CO	Glutathione peroxidase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_6001443_11	555088.DealDRAFT_1127	8.115e-31	133.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_6001443_0	1123060.JONP01000012_gene2839	9.818e-172	554.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,2JU43@204441|Rhodospirillales	204441|Rhodospirillales	CH	FAD binding domain	-	-	1.14.13.114	ko:K14974	ko00760,ko01120,map00760,map01120	M00622	R08764	RC00115	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
GDHHQS3_k127_6001443_14	446462.Amir_2657	3.281e-13	78.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,4EAZB@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS3_k127_6001443_1	485913.Krac_10927	9.708e-72	257.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi	200795|Chloroflexi	H	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
GDHHQS3_k127_6001443_7	1283299.AUKG01000002_gene5135	6.144e-38	147.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
GDHHQS3_k127_6018995_0	926569.ANT_00850	1.344e-129	417.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_6020988_4	266117.Rxyl_1174	2.596e-60	215.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS3_k127_6020988_3	266117.Rxyl_1175	9.07e-102	349.0	COG1840@1|root,COG1840@2|Bacteria,2HRRI@201174|Actinobacteria,4CTU6@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
GDHHQS3_k127_6020988_7	262543.Exig_2829	1.954e-06	61.0	28KBQ@1|root,2Z9YP@2|Bacteria,1TT8R@1239|Firmicutes,4IRFF@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6020988_5	867903.ThesuDRAFT_02069	1.019e-52	210.0	COG1215@1|root,COG1215@2|Bacteria,1UHQZ@1239|Firmicutes,25GH1@186801|Clostridia,3WDPU@538999|Clostridiales incertae sedis	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS3_k127_6020988_0	266117.Rxyl_1181	1.63e-157	522.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_6020988_6	1565129.JSFF01000006_gene2479	1.533e-19	91.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,1T8QK@1236|Gammaproteobacteria,2QCDE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS3_k127_6032222_3	479434.Sthe_2726	2.395e-51	188.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_6032222_6	383372.Rcas_0861	5.757e-22	108.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_6032222_2	472759.Nhal_1953	1.329e-118	396.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1WZZP@135613|Chromatiales	135613|Chromatiales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
GDHHQS3_k127_6032222_5	1122216.AUHW01000015_gene2026	1.67e-46	176.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes	909932|Negativicutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS3_k127_6032222_1	1128421.JAGA01000002_gene997	4.894e-122	403.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_6032222_4	945713.IALB_2765	4.567e-50	197.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_6032222_0	479434.Sthe_3413	9.119e-181	579.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS3_k127_6039854_1	296591.Bpro_2323	1.115e-89	302.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,4AA5A@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
GDHHQS3_k127_6039854_0	1100721.ALKO01000015_gene1068	3.289e-266	823.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,4AAW6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_6040161_0	485913.Krac_10252	8.939e-83	287.0	COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GDHHQS3_k127_6040161_3	1082933.MEA186_25829	1.459e-59	215.0	COG0500@1|root,COG2226@2|Bacteria,1QYM4@1224|Proteobacteria,2VFGA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_6040161_2	1121022.ABENE_03665	6.641e-61	227.0	COG1633@1|root,COG3369@1|root,COG3592@1|root,COG1633@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,1RCN9@1224|Proteobacteria,2U878@28211|Alphaproteobacteria,2KHJ4@204458|Caulobacterales	204458|Caulobacterales	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,Ferritin-like,zf-CDGSH
GDHHQS3_k127_6040161_1	469383.Cwoe_4585	1.42e-65	234.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_6040161_4	479434.Sthe_1406	7.231e-45	168.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi,27YGM@189775|Thermomicrobia	189775|Thermomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_6040161_5	525904.Tter_1099	2.827e-34	149.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6062929_3	1123389.ATXJ01000047_gene435	1.299e-23	113.0	COG1277@1|root,COG1277@2|Bacteria,1WN4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GDHHQS3_k127_6062929_1	324602.Caur_3059	2.136e-77	269.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi,376R4@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_6062929_0	1134413.ANNK01000091_gene76	9.738e-123	409.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_6062929_2	234267.Acid_2792	1.725e-27	114.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,3Y4XJ@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9
GDHHQS3_k127_6106690_2	358220.C380_02840	6.574e-46	171.0	COG2203@1|root,COG2203@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria,4ACU3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Pfam:Pyridox_oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
GDHHQS3_k127_6106690_0	1382356.JQMP01000003_gene1617	7.873e-65	243.0	COG2206@1|root,COG2206@2|Bacteria,2GBKK@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
GDHHQS3_k127_6106690_1	1380394.JADL01000002_gene1437	1.324e-59	209.0	2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6114614_2	1370125.AUWT01000018_gene4048	5.008e-10	70.0	COG5519@1|root,COG5519@2|Bacteria,2I7XJ@201174|Actinobacteria,23C0Q@1762|Mycobacteriaceae	201174|Actinobacteria	L	Bifunctional DNA primase/polymerase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Prim-Pol
GDHHQS3_k127_6114614_1	926569.ANT_20730	3.987e-37	163.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS3_k127_6114614_0	1396.DJ87_4920	1.103e-49	204.0	COG0553@1|root,COG0553@2|Bacteria,1UZQK@1239|Firmicutes,4HGNM@91061|Bacilli,1ZFDB@1386|Bacillus	91061|Bacilli	KL	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
GDHHQS3_k127_6139117_0	644966.Tmar_0825	3.968e-93	314.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WCD0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_6139117_1	1168034.FH5T_02060	9.35e-13	71.0	COG2827@1|root,COG2827@2|Bacteria,4P9EH@976|Bacteroidetes,2FZ8T@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS3_k127_6140840_2	485913.Krac_8116	3.393e-08	57.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi	200795|Chloroflexi	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_6140840_0	479434.Sthe_3015	7.954e-181	582.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_6140840_1	1206731.BAGB01000164_gene4294	2.781e-128	419.0	COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria,4FZZ7@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_6145366_1	383372.Rcas_0296	1.204e-09	69.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi,375JI@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6145366_0	1121468.AUBR01000021_gene2827	6.308e-97	330.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
GDHHQS3_k127_6194389_0	886293.Sinac_0625	4.216e-91	313.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	2|Bacteria	S	PFAM Peptidase M16 inactive domain	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_6194389_1	1385515.N791_02060	3.781e-25	113.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS3_k127_6194389_2	485913.Krac_4457	0.0002609	48.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6197544_1	1292034.OR37_02494	4.759e-50	181.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,2KG29@204458|Caulobacterales	204458|Caulobacterales	G	PFAM Amylo-alpha-16-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GDHHQS3_k127_6197544_0	450851.PHZ_c3255	0.0	1076.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2TRMQ@28211|Alphaproteobacteria,2KG0H@204458|Caulobacterales	204458|Caulobacterales	G	PFAM glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS3_k127_6268905_11	867903.ThesuDRAFT_01723	7.159e-07	52.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,258QY@186801|Clostridia,3WDPB@538999|Clostridiales incertae sedis	186801|Clostridia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
GDHHQS3_k127_6268905_8	316274.Haur_0039	1.448e-18	96.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_6268905_2	886293.Sinac_7589	3.214e-53	194.0	COG2258@1|root,COG2258@2|Bacteria,2IZG5@203682|Planctomycetes	203682|Planctomycetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
GDHHQS3_k127_6268905_0	311424.DhcVS_1515	7.542e-164	524.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
GDHHQS3_k127_6268905_4	701176.VIBRN418_06631	3.134e-41	157.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria,1XY7E@135623|Vibrionales	135623|Vibrionales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
GDHHQS3_k127_6268905_10	1122939.ATUD01000003_gene3422	1.103e-07	57.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria,4CQVA@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6268905_7	1238182.C882_3853	5.537e-24	103.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2UBU4@28211|Alphaproteobacteria,2JTUG@204441|Rhodospirillales	204441|Rhodospirillales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_6268905_3	1121468.AUBR01000051_gene1994	1.189e-50	197.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,42G2S@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_6268905_9	926550.CLDAP_05300	4.696e-18	85.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_6268905_5	926550.CLDAP_05300	1.16e-34	134.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_6268905_1	292459.STH404	1.022e-76	267.0	COG0702@1|root,COG0702@2|Bacteria,1VEC8@1239|Firmicutes,25BCI@186801|Clostridia	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GDHHQS3_k127_6268905_6	1121085.AUCI01000002_gene3860	4.274e-25	112.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_627832_1	1382358.JHVN01000007_gene381	0.0004564	50.0	COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli	91061|Bacilli	S	DinB superfamily	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_627832_0	926550.CLDAP_22040	6.53e-118	404.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS3_k127_6280183_3	1499684.CCNP01000020_gene2477	4.829e-32	128.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_6280183_0	1121430.JMLG01000011_gene354	1.08e-170	552.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,25ZY6@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_6280183_4	756272.Plabr_3719	7.837e-17	93.0	COG0265@1|root,COG0793@1|root,COG0265@2|Bacteria,COG0793@2|Bacteria,2IY5I@203682|Planctomycetes	203682|Planctomycetes	O	PDZ domain (Also known as DHR	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_6280183_2	926569.ANT_22650	5.359e-63	235.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_6280183_1	429009.Adeg_1028	2.867e-71	249.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,42G27@68295|Thermoanaerobacterales	186801|Clostridia	K	response regulator	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_6280183_6	1142394.PSMK_15500	0.0006633	47.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_6280183_5	1480694.DC28_10080	3.8e-15	83.0	COG1426@1|root,COG1426@2|Bacteria,2J61E@203691|Spirochaetes	203691|Spirochaetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
GDHHQS3_k127_6324416_2	443152.MDG893_15220	7.642e-43	161.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria	1224|Proteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GDHHQS3_k127_6324416_0	1100720.ALKN01000052_gene507	1.452e-130	430.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_6324416_1	479434.Sthe_2971	2.138e-43	169.0	COG2267@1|root,COG2267@2|Bacteria,2G6MI@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_6324416_3	479434.Sthe_3025	1.142e-07	59.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
GDHHQS3_k127_6352402_2	1163617.SCD_n01883	3.546e-59	206.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
GDHHQS3_k127_6352402_1	1123393.KB891317_gene2470	1.943e-93	310.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria,1KSVN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
GDHHQS3_k127_6352402_0	292415.Tbd_1645	3.099e-143	458.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
GDHHQS3_k127_6352702_1	450851.PHZ_c3049	7.978e-90	306.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2U5GA@28211|Alphaproteobacteria,2KK2A@204458|Caulobacterales	204458|Caulobacterales	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
GDHHQS3_k127_6352702_0	450851.PHZ_c3048	1.985e-225	706.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2U05M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein containing von Willebrand factor type A (VWA) domain	MA20_34745	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
GDHHQS3_k127_6366010_1	639030.JHVA01000001_gene1152	1.382e-26	111.0	COG0689@1|root,COG0689@2|Bacteria,3Y2FP@57723|Acidobacteria,2JHM3@204432|Acidobacteriia	204432|Acidobacteriia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GDHHQS3_k127_6366010_0	1121430.JMLG01000005_gene792	2.132e-85	298.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GDHHQS3_k127_6391975_0	525904.Tter_0396	1.609e-99	330.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_6391975_2	1449353.JQMQ01000005_gene4561	6.06e-09	68.0	2EWB1@1|root,33PPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
GDHHQS3_k127_6391975_1	1382306.JNIM01000001_gene160	1.949e-20	98.0	COG1695@1|root,COG1695@2|Bacteria,2G7I0@200795|Chloroflexi	200795|Chloroflexi	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GDHHQS3_k127_6465297_3	1356854.N007_16940	1.067e-42	168.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,279JT@186823|Alicyclobacillaceae	91061|Bacilli	CH	D-isomer specific 2-hydroxyacid dehydrogenase	yvcT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_6465297_0	266117.Rxyl_1110	1.181e-186	595.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
GDHHQS3_k127_6465297_2	485913.Krac_10957	1.461e-44	170.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS3_k127_6465297_1	485913.Krac_2496	1.41e-122	413.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_647887_2	1280390.CBQR020000100_gene2280	3.284e-05	48.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,27516@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_647887_0	926560.KE387023_gene3327	9.252e-34	141.0	COG2062@1|root,COG2062@2|Bacteria,1WN47@1297|Deinococcus-Thermus	2|Bacteria	T	phosphohistidine phosphatase, SixA	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_647887_1	1869.MB27_38505	7.983e-17	96.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4DAE2@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_6480465_5	44251.PDUR_25250	4.857e-08	57.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,26ZW4@186822|Paenibacillaceae	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
GDHHQS3_k127_6480465_2	322710.Avin_29300	6.931e-16	85.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_6480465_0	1382306.JNIM01000001_gene1045	1.905e-56	205.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_6480465_1	344747.PM8797T_24541	2.306e-43	164.0	COG3153@1|root,COG3153@2|Bacteria,2IZPX@203682|Planctomycetes	203682|Planctomycetes	S	Acetyltransferase (GNAT) family	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
GDHHQS3_k127_6480465_4	420324.KI911962_gene1968	3.912e-09	64.0	COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,2U9J8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS3_k127_6480465_3	1382356.JQMP01000003_gene1900	7.345e-14	72.0	COG2897@1|root,COG2897@2|Bacteria,2G8NA@200795|Chloroflexi,27Y2I@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_6483688_1	700598.Niako_4637	3.837e-12	69.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes,1IZDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_6483688_0	251229.Chro_3389	1.882e-44	173.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_6483688_2	247490.KSU1_B0533	2.125e-06	55.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS3_k127_6524112_2	1094980.Mpsy_0997	2.334e-43	167.0	COG0683@1|root,arCOG01021@2157|Archaea,2Y6Q1@28890|Euryarchaeota,2NAW8@224756|Methanomicrobia	224756|Methanomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_6524112_1	392499.Swit_3062	4.995e-163	523.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske (2Fe-2S) domain-containing protein	ligX	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
GDHHQS3_k127_6524112_0	1123508.JH636444_gene5358	1.323e-176	567.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS3_k127_6526489_0	525904.Tter_1052	1.343e-164	527.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS3_k127_6526489_1	634497.HAH_2513	3.275e-52	200.0	COG4427@1|root,arCOG09080@2157|Archaea,2XWG2@28890|Euryarchaeota,23TPM@183963|Halobacteria	183963|Halobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
GDHHQS3_k127_6526489_2	390989.JOEG01000011_gene183	7.309e-38	145.0	COG0454@1|root,COG0454@2|Bacteria,2I32U@201174|Actinobacteria,4DF43@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_6526489_3	272134.KB731324_gene3923	1.623e-06	52.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G027@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg,Trans_reg_C
GDHHQS3_k127_6569468_0	552811.Dehly_0834	3.572e-143	464.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi,34D5Q@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_6569468_1	635013.TherJR_2036	2.194e-30	130.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,24GTJ@186801|Clostridia,262SJ@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS3_k127_6569468_2	251221.35211310	7.103e-29	121.0	COG0838@1|root,COG0838@2|Bacteria,1G5RH@1117|Cyanobacteria	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
GDHHQS3_k127_6569468_3	1037409.BJ6T_28130	9.545e-09	59.0	28Y26@1|root,2ZJXS@2|Bacteria,1PAKD@1224|Proteobacteria,2UYIU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6579761_0	1134413.ANNK01000089_gene360	1.463e-104	353.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_6579761_2	1449063.JMLS01000005_gene3101	1.087e-54	207.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes	1239|Firmicutes	T	hydrolase (HAD superfamily)	-	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_6579761_1	311424.DhcVS_310	1.785e-84	296.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,34CIT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS3_k127_6605227_0	926550.CLDAP_15350	1.847e-137	466.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
GDHHQS3_k127_6605227_1	645991.Sgly_2829	7.151e-49	177.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,2610Y@186807|Peptococcaceae	186801|Clostridia	T	Elongation factor Tu domain 2	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_6605575_2	335541.Swol_0461	4.849e-12	70.0	COG1937@1|root,COG1937@2|Bacteria,1UQUF@1239|Firmicutes,258KU@186801|Clostridia,42KWZ@68298|Syntrophomonadaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS3_k127_6605575_1	240292.Ava_2654	6.278e-39	147.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HNFW@1161|Nostocales	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_6605575_0	1157490.EL26_21220	2.488e-94	319.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,278Z3@186823|Alicyclobacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_6605575_3	331869.BAL199_29535	1.545e-09	65.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,4BPDB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_6644846_1	867903.ThesuDRAFT_00644	1.65e-50	190.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WCKP@538999|Clostridiales incertae sedis	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS3_k127_6644846_0	1123368.AUIS01000010_gene2358	5.697e-138	449.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,2NBRS@225057|Acidithiobacillales	225057|Acidithiobacillales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GDHHQS3_k127_6644846_2	335543.Sfum_1952	5.429e-21	93.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GDHHQS3_k127_6644859_5	1173026.Glo7428_3615	3.689e-06	56.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_6644859_1	552811.Dehly_1272	1.752e-76	268.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi,34CSE@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Polyprenyl synthetase	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_6644859_3	255470.cbdbA887	1.837e-54	208.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,34D4Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS3_k127_6644859_0	552811.Dehly_1271	7.933e-212	672.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,34D7N@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
GDHHQS3_k127_6644859_4	1118153.MOY_03233	5.474e-11	72.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XJNK@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphoglycolate phosphatase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_6644859_2	1128421.JAGA01000002_gene486	4.927e-55	201.0	COG1381@1|root,COG1381@2|Bacteria,2NPV3@2323|unclassified Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS3_k127_6644859_6	313589.JNB_12633	4.269e-05	48.0	COG0494@1|root,COG0494@2|Bacteria,2I3XE@201174|Actinobacteria,4FJZ2@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_6668644_0	309801.trd_1936	8.325e-66	238.0	COG0771@1|root,COG0771@2|Bacteria,2GBHB@200795|Chloroflexi,27XXI@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
GDHHQS3_k127_6668644_1	525904.Tter_0222	1.721e-57	215.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GDHHQS3_k127_6668644_2	311424.DhcVS_824	6.356e-09	57.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,34CJR@301297|Dehalococcoidia	301297|Dehalococcoidia	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_6703076_1	1207063.P24_15621	1.107e-101	339.0	COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2TUAQ@28211|Alphaproteobacteria,2JTIA@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_6703076_2	273057.SSO1225	1.086e-95	327.0	COG0446@1|root,arCOG01070@2157|Archaea,2XSN5@28889|Crenarchaeota	28889|Crenarchaeota	S	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
GDHHQS3_k127_6703076_4	357808.RoseRS_3555	2.85e-56	200.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi,37744@32061|Chloroflexia	32061|Chloroflexia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_6703076_0	880073.Calab_0629	1.075e-128	422.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS3_k127_6703076_3	1125863.JAFN01000001_gene1772	4.664e-94	315.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
GDHHQS3_k127_6705814_0	1382306.JNIM01000001_gene274	5.568e-221	699.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GDHHQS3_k127_6705814_1	1437882.AZRU01000095_gene1250	1.377e-09	66.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_6724029_2	512565.AMIS_18380	8.289e-42	154.0	COG3526@1|root,COG3526@2|Bacteria,2IRQ4@201174|Actinobacteria,4DK31@85008|Micromonosporales	201174|Actinobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS3_k127_6724029_0	1100720.ALKN01000052_gene507	2.219e-135	444.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_6724029_1	760568.Desku_0392	1.091e-68	249.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,260VE@186807|Peptococcaceae	186801|Clostridia	EGP	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_6724029_4	58344.JOEL01000044_gene886	0.0002429	45.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
GDHHQS3_k127_6724029_3	1122919.KB905595_gene4207	3.037e-11	76.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_6732183_1	118168.MC7420_8108	3.173e-40	162.0	COG0673@1|root,COG0673@2|Bacteria,1G18K@1117|Cyanobacteria,1H8TN@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, C-terminal alpha beta domain	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_6732183_4	1267005.KB911256_gene1762	0.0003006	46.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,3N64U@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_6732183_2	1304877.KI519400_gene1569	4.403e-27	116.0	COG0251@1|root,COG0251@2|Bacteria,1RB9R@1224|Proteobacteria,2U63U@28211|Alphaproteobacteria,3JYEU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	MA20_21375	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_6732183_0	1134413.ANNK01000089_gene360	4.388e-115	385.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_6732183_3	164757.Mjls_4569	6.025e-08	58.0	COG4447@1|root,COG4447@2|Bacteria,2GN53@201174|Actinobacteria,237Q9@1762|Mycobacteriaceae	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GDHHQS3_k127_6762162_0	552811.Dehly_1200	1.045e-269	842.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi,34CMC@301297|Dehalococcoidia	301297|Dehalococcoidia	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_6762162_2	525904.Tter_0060	8.888e-83	291.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_6762162_1	926550.CLDAP_08140	1.433e-114	393.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_6770845_8	1131730.BAVI_16242	1.543e-09	62.0	COG1657@1|root,COG1657@2|Bacteria,1UZVS@1239|Firmicutes,4HDE7@91061|Bacilli,1ZDJT@1386|Bacillus	91061|Bacilli	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Gram_pos_anchor,Prenyltrans,SLH,SQHop_cyclase_C
GDHHQS3_k127_6770845_7	945713.IALB_2304	1.032e-21	104.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6770845_6	1121396.KB893105_gene1813	4.715e-40	165.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2MPYF@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_6770845_0	266117.Rxyl_2540	1.891e-238	756.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_6770845_2	929712.KI912613_gene2740	3.018e-90	307.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_6770845_3	266117.Rxyl_1743	1.904e-61	223.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria,4CT8V@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_6770845_4	316274.Haur_3275	7.037e-61	212.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi,375FA@32061|Chloroflexia	32061|Chloroflexia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS3_k127_6770845_5	1382306.JNIM01000001_gene3553	2.972e-58	208.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS3_k127_6770845_1	1382306.JNIM01000001_gene3552	9.411e-149	478.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_6796076_0	240015.ACP_2495	1.137e-71	243.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_6796076_2	649764.HMPREF0762_01806	4.595e-29	121.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS3_k127_6796076_1	1336243.JAEA01000012_gene2944	1.889e-38	157.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,1JQUB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GDHHQS3_k127_6817273_1	330214.NIDE2582	7.511e-30	120.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	40117|Nitrospirae	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_6817273_4	1122138.AQUZ01000026_gene2982	6.149e-07	59.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2I4QM@201174|Actinobacteria,4DU0E@85009|Propionibacteriales	201174|Actinobacteria	P	CopC domain	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GDHHQS3_k127_6817273_0	1122939.ATUD01000001_gene247	2.635e-31	143.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2I7A2@201174|Actinobacteria,4CTUX@84995|Rubrobacteria	84995|Rubrobacteria	P	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GDHHQS3_k127_6817273_3	545264.KB898744_gene1964	3.628e-17	96.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
GDHHQS3_k127_6817273_2	644282.Deba_1364	1.223e-19	90.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
GDHHQS3_k127_6832501_1	926550.CLDAP_09190	8.131e-37	144.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_6832501_0	518766.Rmar_2012	5.516e-121	394.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GDHHQS3_k127_6883894_0	748247.AZKH_2968	1.02e-228	734.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GDHHQS3_k127_6883894_1	66377.JOBH01000002_gene723	3.036e-11	71.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_6891193_0	1157637.KB892097_gene1189	6.713e-225	711.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS3_k127_6891193_1	644283.Micau_4855	5.676e-49	179.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4D9QW@85008|Micromonosporales	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_693512_0	1521187.JPIM01000067_gene1061	2.149e-167	538.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,375DR@32061|Chloroflexia	32061|Chloroflexia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS3_k127_693512_3	1449357.JQLK01000001_gene1693	1.024e-06	53.0	2DSVR@1|root,33HKS@2|Bacteria,1WKIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
GDHHQS3_k127_693512_2	1054860.KB913030_gene2628	7.125e-28	117.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_693512_1	86416.Clopa_3705	8.345e-37	149.0	COG2159@1|root,COG2159@2|Bacteria,1VRTB@1239|Firmicutes	1239|Firmicutes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GDHHQS3_k127_6942506_6	754252.PFREUD_14070	1.503e-09	59.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DNG8@85009|Propionibacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS3_k127_6942506_4	498761.HM1_1051	2.862e-31	128.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
GDHHQS3_k127_6942506_0	1382306.JNIM01000001_gene2616	1.975e-180	586.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_6942506_1	485913.Krac_2496	5.577e-170	553.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_6942506_9	331869.BAL199_12101	8.003e-07	57.0	COG1846@1|root,COG1846@2|Bacteria,1PC0Z@1224|Proteobacteria,2VAWA@28211|Alphaproteobacteria,4BSZS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS3_k127_6942506_2	1267533.KB906735_gene4495	1.399e-140	458.0	COG0579@1|root,COG0579@2|Bacteria,3Y6NN@57723|Acidobacteria	57723|Acidobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
GDHHQS3_k127_6942506_7	203120.LEUM_0920	3.057e-07	58.0	COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,4IFG0@91061|Bacilli,4AXSP@81850|Leuconostocaceae	91061|Bacilli	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS3_k127_6942506_8	59196.RICGR_0488	4.434e-07	62.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	CBM_6,Cellulase,GT87,PD40,VCBS
GDHHQS3_k127_6942506_3	525904.Tter_2547	1.405e-33	142.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_6942506_5	42256.RradSPS_0565	3.137e-17	92.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_6979195_3	224324.aq_1010	1.313e-09	60.0	COG1028@1|root,COG1028@2|Bacteria,2G53D@200783|Aquificae	200783|Aquificae	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_6979195_1	1210884.HG799462_gene8441	6.344e-40	155.0	COG0720@1|root,COG0720@2|Bacteria,2J000@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_6979195_0	530564.Psta_4201	3.392e-61	218.0	COG0603@1|root,COG0603@2|Bacteria,2IZ5W@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GDHHQS3_k127_6979195_2	926569.ANT_06860	5.136e-20	94.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS3_k127_6994411_1	1121382.JQKG01000012_gene236	3.6e-96	333.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GDHHQS3_k127_6994411_0	479434.Sthe_2057	1.685e-118	387.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_6998070_0	479434.Sthe_1801	1.189e-114	377.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_6998070_1	644966.Tmar_1263	1.074e-85	299.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS3_k127_6998070_2	1267533.KB906736_gene978	1.465e-75	270.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria,2JK6X@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
GDHHQS3_k127_6998070_3	1329516.JPST01000003_gene1117	3.546e-56	202.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli,27CKF@186824|Thermoactinomycetaceae	91061|Bacilli	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
GDHHQS3_k127_6998885_0	309801.trd_0177	4.516e-118	387.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_6998885_1	926550.CLDAP_28940	1.517e-14	86.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	YSIRK_signal
GDHHQS3_k127_7046422_1	296591.Bpro_1996	4.377e-149	474.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,4AC8B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
GDHHQS3_k127_7046422_0	296591.Bpro_1995	4.027e-179	567.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,4AAT0@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_7046422_2	614083.AWQR01000018_gene1767	1.944e-51	186.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,4AB8Q@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_7050122_1	296591.Bpro_2311	2.593e-83	282.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,4ABBS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_7050122_2	296591.Bpro_2310	1.83e-60	211.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4ADYB@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS3_k127_7050122_0	296591.Bpro_2309	1.953e-156	496.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,4AABN@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS3_k127_7065234_1	42256.RradSPS_2165	7.564e-44	170.0	COG1226@1|root,COG1226@2|Bacteria,2HPDW@201174|Actinobacteria,4CQRY@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
GDHHQS3_k127_7065234_0	552811.Dehly_0519	1.004e-103	344.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,34CM6@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
GDHHQS3_k127_7067762_2	552811.Dehly_0557	1.365e-31	139.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS3_k127_7067762_0	255470.cbdbA543	6.804e-133	432.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,34CN2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_7067762_1	1380394.JADL01000004_gene6131	2.753e-97	333.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria,2JV7T@204441|Rhodospirillales	204441|Rhodospirillales	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
GDHHQS3_k127_70714_3	1121271.AUCM01000006_gene275	3.355e-31	126.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1062 Zn-dependent alcohol dehydrogenases, class III	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_70714_0	134676.ACPL_2404	2.895e-167	530.0	COG0174@1|root,COG0174@2|Bacteria,2GKU9@201174|Actinobacteria,4DH1U@85008|Micromonosporales	201174|Actinobacteria	E	Glutamine synthetase, beta-Grasp domain	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_70714_2	523845.AQXV01000040_gene1700	5.574e-36	139.0	COG0347@1|root,arCOG02305@2157|Archaea,2XYN5@28890|Euryarchaeota,23R3U@183939|Methanococci	183939|Methanococci	E	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS3_k127_70714_1	671143.DAMO_1683	1.071e-147	481.0	COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria	2|Bacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iHN637.CLJU_c42670,iYO844.BSU36510	Ammonium_transp
GDHHQS3_k127_70714_4	1121878.AUGL01000001_gene458	4.304e-09	62.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rstA	-	-	ko:K02483,ko:K07661	ko02020,map02020	M00446	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_7074113_0	1128421.JAGA01000002_gene7	2.475e-276	865.0	COG0542@1|root,COG0542@2|Bacteria,2NQAB@2323|unclassified Bacteria	2|Bacteria	O	C-terminal, D2-small domain, of ClpB protein	clpB	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_7088616_1	329726.AM1_2612	6.26e-105	347.0	COG0046@1|root,COG0046@2|Bacteria,1G228@1117|Cyanobacteria	1117|Cyanobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_7088616_3	1279017.AQYJ01000029_gene3723	4.007e-41	158.0	COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,1S3I4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_7088616_2	311424.DhcVS_623	2.2e-75	265.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34CTP@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_7088616_0	926569.ANT_15990	2.801e-194	625.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS3_k127_709087_1	1382306.JNIM01000001_gene4038	4.626e-35	149.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GDHHQS3_k127_709087_0	1385520.N802_11400	1.019e-41	160.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4FFVU@85021|Intrasporangiaceae	201174|Actinobacteria	P	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GDHHQS3_k127_7095991_0	357808.RoseRS_3115	2.004e-221	698.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,376WB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS3_k127_7095991_1	903818.KI912268_gene2680	1.096e-76	262.0	COG0176@1|root,COG0176@2|Bacteria,3Y4BN@57723|Acidobacteria	57723|Acidobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS3_k127_7095991_2	1382306.JNIM01000001_gene3924	5.062e-47	174.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_7111284_0	1128421.JAGA01000004_gene2629	4.62e-162	524.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_7111284_1	1283299.AUKG01000001_gene1924	1.198e-25	111.0	COG0662@1|root,COG0662@2|Bacteria,2GXUC@201174|Actinobacteria,4CT1G@84995|Rubrobacteria	84995|Rubrobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
GDHHQS3_k127_7121763_0	255470.cbdbA5	2.7e-247	785.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,34CRS@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS3_k127_7121763_1	886293.Sinac_0788	5.832e-26	108.0	COG0384@1|root,COG0384@2|Bacteria,2IYZ8@203682|Planctomycetes	203682|Planctomycetes	S	epimerase, PhzC PhzF homolog	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GDHHQS3_k127_7124693_5	684949.ATTJ01000001_gene2712	1.249e-12	78.0	2E4CV@1|root,32Z89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2680
GDHHQS3_k127_7124693_3	656024.FsymDg_2032	1.396e-23	113.0	COG2267@1|root,COG2267@2|Bacteria,2H6J4@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	3.1.1.24,3.7.1.9	ko:K01055,ko:K10216,ko:K18092	ko00362,ko00622,ko00642,ko00643,ko01100,ko01120,ko01220,map00362,map00622,map00642,map00643,map01100,map01120,map01220	M00568,M00569	R02604,R02991,R05362,R05366,R05865	RC00272,RC00752,RC00753,RC00754,RC00755,RC00825,RC01337,RC01485	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GDHHQS3_k127_7124693_1	1382356.JQMP01000003_gene2062	9.251e-41	166.0	COG2223@1|root,COG2223@2|Bacteria,2GBND@200795|Chloroflexi,27XPQ@189775|Thermomicrobia	189775|Thermomicrobia	P	PUCC protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_7124693_6	439481.Aboo_1117	0.0001063	47.0	COG1601@1|root,COG3269@1|root,arCOG01640@2157|Archaea,arCOG01641@2157|Archaea,2XTVZ@28890|Euryarchaeota,3F2N9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
GDHHQS3_k127_7124693_0	1120959.ATXF01000004_gene2973	7.232e-85	291.0	COG0463@1|root,COG0463@2|Bacteria,2IPT1@201174|Actinobacteria,4FP14@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS3_k127_7124693_2	573061.Clocel_0350	1.514e-26	124.0	COG4713@1|root,COG4713@2|Bacteria,1V77Y@1239|Firmicutes,24C6B@186801|Clostridia,36IH2@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS3_k127_7124693_4	1231391.AMZF01000069_gene2124	5.787e-18	86.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_7153705_0	383372.Rcas_2148	4.096e-94	327.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS3_k127_7153705_1	457425.XNR_1203	7.819e-37	149.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_7157555_0	552811.Dehly_0915	1.222e-298	931.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,34D66@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS3_k127_7157555_1	1089553.Tph_c14440	3.926e-05	48.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GKK@68295|Thermoanaerobacterales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GDHHQS3_k127_71667_0	552811.Dehly_0534	1.614e-242	771.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi,34CYC@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS3_k127_71667_1	338963.Pcar_1560	3.657e-29	118.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43SNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS3_k127_71667_4	101510.RHA1_ro00055	3.397e-08	63.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4FU2A@85025|Nocardiaceae	201174|Actinobacteria	S	AAA domain	-	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
GDHHQS3_k127_71667_2	1288484.APCS01000073_gene283	1.013e-12	78.0	2CH9R@1|root,33MNW@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS3_k127_71667_3	443906.CMM_0871	2.859e-09	66.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria,4FMEI@85023|Microbacteriaceae	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS3_k127_7167259_2	196162.Noca_4966	2.544e-07	57.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
GDHHQS3_k127_7167259_1	33876.JNXY01000024_gene4944	1.691e-28	123.0	COG1309@1|root,COG1309@2|Bacteria,2IIM0@201174|Actinobacteria,4DM5D@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
GDHHQS3_k127_7167259_0	404589.Anae109_2804	3.521e-72	255.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42SJR@68525|delta/epsilon subdivisions,2WRRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_7174780_0	1206731.BAGB01000164_gene4285	3.742e-22	109.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_7174780_1	28444.JODQ01000002_gene4629	1.942e-10	68.0	COG3193@1|root,COG3193@2|Bacteria,2IHWI@201174|Actinobacteria,4EKTZ@85012|Streptosporangiales	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
GDHHQS3_k127_7183783_3	391623.TERMP_00302	8.398e-42	171.0	COG0534@1|root,arCOG01731@2157|Archaea,2XUU4@28890|Euryarchaeota,242ZQ@183968|Thermococci	183968|Thermococci	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS3_k127_7183783_2	929703.KE386491_gene3854	1.283e-56	216.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,47KI3@768503|Cytophagia	976|Bacteroidetes	V	PFAM Multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GDHHQS3_k127_7183783_1	1144310.PMI07_001391	2.108e-74	267.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,4B74E@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
GDHHQS3_k127_7183783_0	525904.Tter_1871	6.822e-167	546.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS3_k127_7183783_4	273057.SSO2071	3.996e-34	139.0	COG1225@1|root,arCOG00310@2157|Archaea,2XRWS@28889|Crenarchaeota	28889|Crenarchaeota	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_7190182_0	552811.Dehly_0109	1.115e-108	360.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi,34D9J@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_7190182_1	479434.Sthe_1601	1.069e-54	201.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
GDHHQS3_k127_7190182_2	1123250.KB908395_gene1883	1.625e-21	109.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4H3WS@909932|Negativicutes	909932|Negativicutes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS3_k127_7235917_3	1479239.JQMU01000001_gene2646	9.389e-25	114.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2K439@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_7235917_0	1366046.HIMB11_01871	1.541e-120	398.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,3ZG33@58840|unclassified Rhodobacteraceae	1224|Proteobacteria	H	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS3_k127_7235917_4	521011.Mpal_0675	6.547e-22	111.0	COG2133@1|root,arCOG03441@1|root,arCOG02796@2157|Archaea,arCOG03441@2157|Archaea,2XT1Q@28890|Euryarchaeota	28890|Euryarchaeota	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,GSDH
GDHHQS3_k127_7235917_1	309801.trd_A0395	2.13e-87	304.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GDHHQS3_k127_7235917_2	479434.Sthe_3193	3.716e-46	179.0	COG1612@1|root,COG1612@2|Bacteria	2|Bacteria	O	heme a metabolic process	ctaB	-	2.5.1.141	ko:K02257,ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07411,R07412	RC00769,RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	3.D.4.4	-	-	COX15-CtaA,UbiA
GDHHQS3_k127_7262020_4	1499967.BAYZ01000014_gene6407	1.263e-77	283.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_7262020_2	313624.NSP_36070	4.385e-102	343.0	COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria,1HMI2@1161|Nostocales	1117|Cyanobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GDHHQS3_k127_7262020_9	1356854.N007_08195	2.279e-38	156.0	COG2267@1|root,COG2267@2|Bacteria,1UHRJ@1239|Firmicutes,4IS7F@91061|Bacilli,27AT4@186823|Alicyclobacillaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_7262020_1	1134413.ANNK01000089_gene360	1.88e-112	378.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,4I68U@91061|Bacilli,1ZDPN@1386|Bacillus	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_7262020_12	317619.ANKN01000046_gene1060	1.171e-06	52.0	COG1061@1|root,COG1061@2|Bacteria,1G4XZ@1117|Cyanobacteria,1MNBG@1212|Prochloraceae	1117|Cyanobacteria	KL	Type III restriction enzyme, res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
GDHHQS3_k127_7262020_5	1173028.ANKO01000112_gene4874	3.224e-51	196.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HA4H@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GDHHQS3_k127_7262020_8	1173028.ANKO01000112_gene4870	1.866e-42	165.0	COG1216@1|root,COG1216@2|Bacteria,1G7TA@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7262020_7	713586.KB900536_gene1745	1.454e-42	170.0	COG1216@1|root,COG1216@2|Bacteria,1QV94@1224|Proteobacteria,1SFFR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7262020_6	1469607.KK073769_gene5390	8.774e-43	169.0	COG1493@1|root,COG1493@2|Bacteria,1GJ93@1117|Cyanobacteria,1HR2P@1161|Nostocales	1117|Cyanobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7262020_11	272134.KB731324_gene4383	6.351e-19	92.0	2E7MG@1|root,3323C@2|Bacteria,1GCRI@1117|Cyanobacteria,1HFKH@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS3_k127_7262020_10	927677.ALVU02000001_gene3540	5.82e-24	111.0	COG0317@1|root,COG0317@2|Bacteria,1GEK3@1117|Cyanobacteria	1117|Cyanobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
GDHHQS3_k127_7262020_3	1173026.Glo7428_1576	1.38e-82	285.0	COG0451@1|root,COG0451@2|Bacteria,1GC7G@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_7262020_13	1123248.KB893370_gene5053	2.868e-05	47.0	COG1112@1|root,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes	976|Bacteroidetes	L	COG1112 Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
GDHHQS3_k127_7345267_2	278963.ATWD01000003_gene170	7.863e-09	62.0	COG1286@1|root,COG1286@2|Bacteria,3Y59W@57723|Acidobacteria,2JJP3@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
GDHHQS3_k127_7345267_0	1121430.JMLG01000032_gene1666	9.54e-51	190.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_7345267_1	479434.Sthe_2339	4.972e-32	131.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia	189775|Thermomicrobia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
GDHHQS3_k127_7388205_0	1231391.AMZF01000029_gene212	7.652e-27	120.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VKYY@28216|Betaproteobacteria,3T2CN@506|Alcaligenaceae	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
GDHHQS3_k127_7388205_2	384765.SIAM614_12883	1.053e-05	55.0	2E3X7@1|root,32YUC@2|Bacteria,1NHDZ@1224|Proteobacteria,2UX0P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7388205_1	257310.BB0728	2.987e-25	108.0	COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2VQ87@28216|Betaproteobacteria,3T2ZG@506|Alcaligenaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	hcaE	-	1.14.12.11,1.14.12.19,1.14.12.3	ko:K03268,ko:K05708	ko00360,ko00361,ko00362,ko00623,ko00625,ko01100,ko01120,ko01220,map00360,map00361,map00362,map00623,map00625,map01100,map01120,map01220	M00545,M00547	R03543,R03559,R05429,R06782,R06783,R06831,R06856,R09151,R09152	RC00098,RC00267,RC00951,RC03011,RC03012,RC03013	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_7392366_2	886293.Sinac_1829	2.327e-07	52.0	COG0723@1|root,COG0723@2|Bacteria,2IZ3E@203682|Planctomycetes	203682|Planctomycetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS3_k127_7392366_0	768710.DesyoDRAFT_5068	1.663e-69	249.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,26327@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_7392366_1	926550.CLDAP_40300	5.752e-66	240.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GDHHQS3_k127_7397103_1	485913.Krac_10690	1.412e-52	196.0	29BBV@1|root,2ZCHD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GDHHQS3_k127_7397103_2	266117.Rxyl_3088	1.32e-40	162.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4CRND@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_7397103_0	1206741.BAFX01000009_gene6882	6.243e-71	248.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4G7CW@85025|Nocardiaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS3_k127_7402354_0	292459.STH124	6.149e-58	213.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7402354_1	867845.KI911784_gene3427	2.201e-05	54.0	29X49@1|root,30IT2@2|Bacteria,2GBJU@200795|Chloroflexi,377RZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7402354_2	1121904.ARBP01000011_gene1572	3.329e-05	51.0	COG0673@1|root,COG0673@2|Bacteria,4NGHW@976|Bacteroidetes,47XR6@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_7405695_0	383372.Rcas_0717	6.858e-97	323.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,375CT@32061|Chloroflexia	32061|Chloroflexia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
GDHHQS3_k127_7405695_7	89187.ISM_07350	1.191e-12	69.0	COG1942@1|root,COG1942@2|Bacteria,1NG98@1224|Proteobacteria,2UK0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	4-oxalocrotonate tautomerase	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase
GDHHQS3_k127_7405695_4	1157640.AQWO01000018_gene5374	1.716e-27	117.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria	201174|Actinobacteria	IQ	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS3_k127_7405695_2	1249627.D779_1897	2.568e-45	180.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1WYG2@135613|Chromatiales	135613|Chromatiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS3_k127_7405695_5	326424.FRAAL5785	9.406e-24	106.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4ETCV@85013|Frankiales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GDHHQS3_k127_7405695_6	671143.DAMO_3098	3.557e-19	92.0	COG2331@1|root,COG2331@2|Bacteria,2NRJX@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_7405695_1	1382306.JNIM01000001_gene3445	6.351e-57	205.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_7405695_3	479434.Sthe_0585	9.563e-40	156.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_7411795_4	1411685.U062_01834	0.0008483	42.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1J4HG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS3_k127_7411795_2	552811.Dehly_1269	8.225e-23	102.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,34CPU@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS3_k127_7411795_3	292459.STH2564	6.598e-21	100.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
GDHHQS3_k127_7411795_1	1382356.JQMP01000003_gene1647	3.62e-41	160.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS3_k127_7411795_0	1382306.JNIM01000001_gene1396	1.058e-163	529.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS3_k127_7415282_0	485913.Krac_8002	1.442e-167	538.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_7415282_4	1229780.BN381_210036	3.463e-05	54.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_7415282_2	234267.Acid_3971	2.157e-152	494.0	COG1252@1|root,COG1252@2|Bacteria,3Y308@57723|Acidobacteria	57723|Acidobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_7415282_1	243274.THEMA_03280	3.706e-162	522.0	COG0205@1|root,COG0205@2|Bacteria,2GC8H@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_7415282_3	1121472.AQWN01000010_gene553	7.334e-53	200.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,260A0@186807|Peptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_7441410_4	710696.Intca_0410	4.263e-37	146.0	2DRYE@1|root,33DPC@2|Bacteria,2IS24@201174|Actinobacteria,4FHPE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7441410_8	518766.Rmar_2288	2.036e-08	64.0	COG5615@1|root,COG5615@2|Bacteria,4P6NC@976|Bacteroidetes,1FK4A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GDHHQS3_k127_7441410_7	1395571.TMS3_0115850	6.236e-24	111.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,1RQ5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_7441410_3	398525.KB900701_gene6709	5.166e-58	211.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,2TR1B@28211|Alphaproteobacteria,3JTVI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_7441410_1	570952.ATVH01000014_gene2208	4.887e-103	338.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,2JRD7@204441|Rhodospirillales	204441|Rhodospirillales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
GDHHQS3_k127_7441410_5	29581.BW37_04103	4.762e-35	142.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_7441410_2	196367.JNFG01000214_gene1287	7.904e-62	227.0	COG3384@1|root,COG3384@2|Bacteria,1R6R4@1224|Proteobacteria,2W1RP@28216|Betaproteobacteria,1K5YM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15065	ko00627,ko01120,map00627,map01120	-	R09272	RC01369	ko00000,ko00001,ko01000	-	-	-	LigB
GDHHQS3_k127_7441410_6	1123239.KB898623_gene1228	1.623e-26	119.0	COG2807@1|root,COG2807@2|Bacteria,1UJ09@1239|Firmicutes,4ISZA@91061|Bacilli	91061|Bacilli	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_7470942_2	525904.Tter_0396	3.875e-26	109.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_7470942_3	1121859.KB890738_gene3345	2.177e-24	108.0	COG1225@1|root,COG1225@2|Bacteria,4NGWI@976|Bacteroidetes,47Q83@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_7470942_0	926569.ANT_27550	1.865e-66	236.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
GDHHQS3_k127_7470942_1	861299.J421_2704	3.374e-52	186.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS3_k127_7495812_5	1410618.JNKI01000002_gene1094	3.443e-27	115.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4H20N@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS3_k127_7495812_2	867903.ThesuDRAFT_00685	1.9e-101	344.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS3_k127_7495812_6	1122609.AUGT01000012_gene4315	1.024e-17	93.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4DRPK@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS3_k127_7495812_1	926569.ANT_23450	8.962e-114	381.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS3_k127_7495812_0	926569.ANT_23460	2.606e-122	402.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS3_k127_7495812_4	215803.DB30_0119	2.743e-41	160.0	2CK59@1|root,32VV2@2|Bacteria,1P616@1224|Proteobacteria,4329Y@68525|delta/epsilon subdivisions,2X772@28221|Deltaproteobacteria,2YVDY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7495812_3	1089546.AQUI01000002_gene245	1.56e-67	237.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_7507994_2	868595.Desca_2343	1.046e-61	236.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_7507994_0	292459.STH1031	6.003e-89	310.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_7507994_1	309801.trd_0060	2.01e-64	228.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
GDHHQS3_k127_756098_0	1382306.JNIM01000001_gene1220	4.297e-96	338.0	COG0749@1|root,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_7561906_0	368407.Memar_1826	2.108e-87	305.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2N9VR@224756|Methanomicrobia	224756|Methanomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_7577555_0	1177154.Y5S_01705	0.0	1632.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
GDHHQS3_k127_760188_2	1040989.AWZU01000003_gene6889	8.027e-27	114.0	COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria,3JWZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GDHHQS3_k127_760188_0	526225.Gobs_3683	2.89e-123	405.0	COG1052@1|root,COG1052@2|Bacteria,2I2IC@201174|Actinobacteria,4ETVD@85013|Frankiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	serA2	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_760188_1	1382356.JQMP01000001_gene1227	2.19e-33	143.0	COG0477@1|root,COG2814@2|Bacteria,2G6HS@200795|Chloroflexi,27XYB@189775|Thermomicrobia	189775|Thermomicrobia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_7655877_4	391596.PBAL39_16981	1.004e-11	67.0	COG3548@1|root,COG3548@2|Bacteria,4NSYF@976|Bacteroidetes,1J13W@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GDHHQS3_k127_7655877_1	269797.Mbar_A3576	4.812e-50	186.0	COG3369@1|root,arCOG03174@2157|Archaea,2XX0Q@28890|Euryarchaeota,2NAIG@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART zinc finger, CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
GDHHQS3_k127_7655877_0	234267.Acid_6976	5.192e-130	440.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7655877_2	1122915.AUGY01000020_gene6474	1.455e-29	128.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.1.69,4.1.2.17	ko:K01628,ko:K18256	ko00051,ko00624,ko01120,map00051,map00624,map01120	M00636	R01634,R02262	RC00569,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,UPF0066
GDHHQS3_k127_7655877_3	479434.Sthe_0639	2.383e-14	85.0	2DBT9@1|root,32TY2@2|Bacteria,2G95T@200795|Chloroflexi,27YPQ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_7673698_2	266117.Rxyl_2863	2.59e-08	65.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
GDHHQS3_k127_7673698_0	1121468.AUBR01000030_gene1220	7.275e-84	297.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS3_k127_7673698_1	525904.Tter_1379	4.286e-39	155.0	COG2227@1|root,COG2227@2|Bacteria,2NRDG@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_7673698_3	471874.PROSTU_00497	3.125e-05	52.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,3Z9PJ@586|Providencia	1236|Gammaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	cpsB	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS3_k127_7679307_1	99598.Cal7507_0562	1.391e-84	302.0	COG0604@1|root,COG0604@2|Bacteria,1G3UU@1117|Cyanobacteria,1HK08@1161|Nostocales	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS3_k127_7679307_0	443152.MDG893_15045	1.722e-94	331.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria	1224|Proteobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_7679307_2	1038862.KB893805_gene3805	2.651e-26	126.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2U5AR@28211|Alphaproteobacteria,3JY2T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	MA20_00485	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GDHHQS3_k127_7679307_3	1155714.KB891997_gene781	1.029e-10	67.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
GDHHQS3_k127_7684459_2	309801.trd_A0640	9.608e-12	75.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_7684459_0	886293.Sinac_1196	2.441e-79	280.0	COG0349@1|root,COG0349@2|Bacteria,2IY8T@203682|Planctomycetes	203682|Planctomycetes	J	COG0349 Ribonuclease D	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS3_k127_7684459_1	1183438.GKIL_0453	5.608e-44	173.0	COG1215@1|root,COG1596@1|root,COG1215@2|Bacteria,COG1596@2|Bacteria,1G27R@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7696815_2	329726.AM1_3584	6.378e-13	79.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_7696815_1	357808.RoseRS_3756	3.979e-73	257.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS3_k127_7696815_0	926550.CLDAP_22390	7.239e-98	337.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS3_k127_7705179_1	1089553.Tph_c21570	8.068e-112	374.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
GDHHQS3_k127_7705179_2	1329516.JPST01000035_gene3211	3.137e-42	166.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,27BVF@186824|Thermoactinomycetaceae	91061|Bacilli	H	Cytidylyltransferase-like	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_7705179_0	1200557.JHWV01000005_gene1360	6.38e-231	731.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H2D7@909932|Negativicutes	909932|Negativicutes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS3_k127_7723288_0	479434.Sthe_1034	2.251e-209	657.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_7723288_5	525904.Tter_1056	6.382e-17	83.0	COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S21	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS3_k127_7723288_3	552811.Dehly_0119	1.121e-34	138.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,34DBW@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS3_k127_7723288_1	1382356.JQMP01000003_gene1329	7.434e-107	372.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi,27XNG@189775|Thermomicrobia	189775|Thermomicrobia	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
GDHHQS3_k127_7723288_2	204669.Acid345_2235	5.671e-88	296.0	COG0047@1|root,COG0047@2|Bacteria,3Y2YN@57723|Acidobacteria,2JIBA@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GDHHQS3_k127_7723288_4	1394178.AWOO02000058_gene656	2.232e-28	118.0	COG1670@1|root,COG1670@2|Bacteria,2II7F@201174|Actinobacteria,4EJXA@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_7734714_0	479434.Sthe_1793	3.458e-120	399.0	COG1804@1|root,COG1804@2|Bacteria,2G61Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GDHHQS3_k127_7734714_1	43354.JOIJ01000027_gene3343	3.098e-06	58.0	2DPU0@1|root,333DA@2|Bacteria,2GR9U@201174|Actinobacteria,4E403@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7763274_1	390989.JOEG01000013_gene2562	8.286e-113	372.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GDHHQS3_k127_7763274_0	1254432.SCE1572_38150	6.975e-167	539.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria,2YUBA@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_7823740_1	525368.HMPREF0591_2130	7.406e-40	155.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,2391H@1762|Mycobacteriaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GDHHQS3_k127_7823740_2	926564.KI911755_gene6087	5.62e-16	82.0	28PB4@1|root,2ZC42@2|Bacteria,2GP5R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7823740_0	1121377.KB906398_gene2052	2.204e-46	174.0	28PB4@1|root,2ZC42@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7869985_0	1125973.JNLC01000011_gene602	1.448e-100	339.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GDHHQS3_k127_7869985_1	649747.HMPREF0083_05891	1.999e-83	298.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26QWN@186822|Paenibacillaceae	91061|Bacilli	E	acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_7869985_2	113355.CM001775_gene2081	6.415e-05	56.0	COG1598@1|root,COG1598@2|Bacteria,1G9G2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_7871392_1	477974.Daud_2231	1.5e-48	183.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,261UV@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GDHHQS3_k127_7871392_2	1123267.JONN01000001_gene429	3.607e-08	66.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,2K7JK@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS3_k127_7871392_3	255470.cbdbB2	9.598e-06	49.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_7871392_0	565033.GACE_0658	1.947e-67	237.0	COG2874@1|root,arCOG04148@2157|Archaea,2XUMD@28890|Euryarchaeota,246RT@183980|Archaeoglobi	183980|Archaeoglobi	N	KaiC	-	-	-	ko:K07331	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ATPase
GDHHQS3_k127_7875470_6	28444.JODQ01000006_gene662	1.005e-65	233.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4EFX2@85012|Streptosporangiales	201174|Actinobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_7875470_3	981369.JQMJ01000004_gene5277	8.475e-101	338.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NFPR@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_7875470_9	1313172.YM304_28250	6.625e-51	198.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_7875470_1	867845.KI911784_gene1695	1.599e-165	534.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,374XT@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_7875470_2	479434.Sthe_2126	2.095e-122	400.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_7875470_5	479434.Sthe_2125	4.896e-80	281.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27YYN@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_7875470_4	243164.DET0013	6.114e-83	284.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi,34CQ3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS3_k127_7875470_12	479434.Sthe_0412	4.59e-18	91.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
GDHHQS3_k127_7875470_15	485913.Krac_4745	2.864e-08	66.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_7875470_7	255470.cbdbA530	2.857e-57	205.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,34DAC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS3_k127_7875470_14	311424.DhcVS_496	2.188e-08	61.0	2BPKF@1|root,32IDF@2|Bacteria,2GAWX@200795|Chloroflexi,34DI2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
GDHHQS3_k127_7875470_8	1128421.JAGA01000002_gene539	8.24e-54	202.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS3_k127_7875470_13	485913.Krac_8499	1.389e-15	79.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS3_k127_7875470_11	243164.DET0560	2.371e-29	123.0	COG0711@1|root,COG0711@2|Bacteria,2G76T@200795|Chloroflexi,34CVK@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS3_k127_7875470_10	1123354.AUDR01000012_gene1860	1.454e-30	127.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,1KRRW@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GDHHQS3_k127_7875470_0	525904.Tter_0065	4.219e-219	687.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS3_k127_7907914_0	649831.L083_4253	1.45e-87	299.0	COG1099@1|root,COG1099@2|Bacteria,2HQN4@201174|Actinobacteria,4DI9E@85008|Micromonosporales	201174|Actinobacteria	S	with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7907914_2	675635.Psed_0286	2.922e-77	269.0	COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria,4E2PC@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_7907914_4	1385519.N801_16225	2.151e-67	238.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4FJ7Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS3_k127_7907914_3	1463825.JNXC01000001_gene6059	1.747e-73	258.0	COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria,4E2PC@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_7907914_5	653045.Strvi_1054	3.666e-64	232.0	COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_7907914_1	1123023.JIAI01000018_gene2512	1.521e-80	279.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.16	ko:K05713	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R04376,R06788	RC01140,RC01364	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
GDHHQS3_k127_7907914_6	1196323.ALKF01000189_gene1185	0.0005491	44.0	29R8B@1|root,30C9Q@2|Bacteria,1U9FB@1239|Firmicutes,4IJIN@91061|Bacilli,2713K@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_792106_0	243164.DET0604	1.667e-299	938.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,34CZR@301297|Dehalococcoidia	301297|Dehalococcoidia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GDHHQS3_k127_7930453_1	653045.Strvi_4576	6.681e-23	98.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD1	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_7930453_2	199306.XP_003069420.1	2.726e-09	63.0	COG2169@1|root,2S6W3@2759|Eukaryota,3A7EW@33154|Opisthokonta,3P5YB@4751|Fungi,3QXMD@4890|Ascomycota,20GFD@147545|Eurotiomycetes,3B165@33183|Onygenales,3FP1X@34383|Onygenales incertae sedis	4751|Fungi	K	Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,HTH_AraC
GDHHQS3_k127_7930453_0	1123073.KB899242_gene946	1.628e-105	357.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1X3QM@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase	lig3	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS3_k127_7937435_1	1223544.GSI01S_40_00160	3.538e-05	47.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4GAX4@85026|Gordoniaceae	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
GDHHQS3_k127_7937435_0	1382306.JNIM01000001_gene1299	6.658e-96	326.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
GDHHQS3_k127_7942676_1	322710.Avin_40470	1.109e-07	62.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Preprotein translocase	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS3_k127_7942676_0	552811.Dehly_1469	2.546e-84	300.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,34D7X@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GDHHQS3_k127_7943291_2	448385.sce3333	2.545e-27	117.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,434SZ@68525|delta/epsilon subdivisions,2WZ41@28221|Deltaproteobacteria,2Z19Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7943291_1	448385.sce3333	1.084e-104	349.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,434SZ@68525|delta/epsilon subdivisions,2WZ41@28221|Deltaproteobacteria,2Z19Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7943291_0	1283299.AUKG01000002_gene3757	2.31e-123	424.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CSH3@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
GDHHQS3_k127_7962377_4	858619.CVAR_0193	0.000539	43.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,22JKE@1653|Corynebacteriaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS3_k127_7962377_0	926550.CLDAP_21330	5.326e-75	269.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GDHHQS3_k127_7962377_1	309801.trd_0437	1.013e-47	180.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,27XQ1@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_7962377_2	525904.Tter_2170	1.265e-40	159.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS3_k127_7962377_3	745310.G432_15315	1.291e-13	79.0	2DGNY@1|root,2ZWRP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_796401_0	525904.Tter_0464	7.587e-91	312.0	COG0405@1|root,COG0405@2|Bacteria,2NP14@2323|unclassified Bacteria	2|Bacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_796401_2	1210884.HG799463_gene9684	5.758e-24	115.0	COG4978@1|root,COG4978@2|Bacteria,2J2RY@203682|Planctomycetes	203682|Planctomycetes	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_796401_1	485913.Krac_2859	5.105e-71	254.0	COG2141@1|root,COG2141@2|Bacteria,2G869@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_7976206_7	717605.Theco_1696	2.01e-13	70.0	COG0667@1|root,COG0667@2|Bacteria,1UHXA@1239|Firmicutes,4HU3T@91061|Bacilli,2769J@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7976206_1	448385.sce3333	2.925e-86	297.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,434SZ@68525|delta/epsilon subdivisions,2WZ41@28221|Deltaproteobacteria,2Z19Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7976206_6	1037409.BJ6T_71610	7.644e-19	92.0	COG0346@1|root,COG0346@2|Bacteria,1RJF4@1224|Proteobacteria,2U9AZ@28211|Alphaproteobacteria,3JZMM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_7976206_8	1267534.KB906754_gene2794	5.4e-11	73.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_7976206_5	521674.Plim_4232	7.398e-23	104.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS3_k127_7976206_0	383372.Rcas_1705	1.847e-123	404.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7976206_2	871968.DESME_14475	2.027e-47	190.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_7976206_4	1380390.JIAT01000013_gene286	5.228e-29	133.0	COG2244@1|root,COG2244@2|Bacteria,2HRUX@201174|Actinobacteria,4CTYA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
GDHHQS3_k127_7976206_3	398767.Glov_1499	2.443e-41	167.0	COG0438@1|root,COG0438@2|Bacteria,1NCUN@1224|Proteobacteria,42WRQ@68525|delta/epsilon subdivisions,2WS5Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_7985223_1	547163.BN979_05115	9.885e-14	81.0	COG2267@1|root,COG2267@2|Bacteria,2I8UI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GDHHQS3_k127_7985223_0	1278073.MYSTI_05916	1.765e-111	368.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X5GE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_7985223_2	397288.C806_03182	3.595e-10	71.0	COG3583@1|root,COG3583@2|Bacteria,1UJWV@1239|Firmicutes,25NR5@186801|Clostridia,27MWQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
GDHHQS3_k127_7993256_2	479434.Sthe_1363	3.443e-59	214.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS3_k127_7993256_3	1123288.SOV_5c00600	1.758e-46	177.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GDHHQS3_k127_7993256_9	326427.Cagg_0917	6.979e-05	53.0	COG1722@1|root,COG1722@2|Bacteria,2G9U8@200795|Chloroflexi,3761B@32061|Chloroflexia	32061|Chloroflexia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS3_k127_7993256_4	926569.ANT_18490	1.074e-36	155.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS3_k127_7993256_7	886293.Sinac_2520	3.294e-10	63.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_7993256_0	1134413.ANNK01000091_gene77	6.977e-95	323.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes,4HDDV@91061|Bacilli,1ZEPT@1386|Bacillus	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_7993256_6	69395.JQLZ01000006_gene2054	2.649e-21	99.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_7993256_5	643867.Ftrac_1682	7.214e-28	121.0	29X2E@1|root,30IQW@2|Bacteria,4P919@976|Bacteroidetes,47WI2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
GDHHQS3_k127_7993256_8	7213.XP_004522493.1	1.224e-06	55.0	COG0446@1|root,KOG1336@2759|Eukaryota,38CNG@33154|Opisthokonta,3BH1J@33208|Metazoa,3CTAN@33213|Bilateria,41W6U@6656|Arthropoda,3SHEB@50557|Insecta,45268@7147|Diptera	33208|Metazoa	S	It is involved in the biological process described with oxidation-reduction process	-	GO:0006915,GO:0008150,GO:0008219,GO:0009987,GO:0012501,GO:0097194	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C,Rieske
GDHHQS3_k127_7993256_1	292459.STH998	1.772e-85	295.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
GDHHQS3_k127_8050791_4	1121430.JMLG01000007_gene2572	5.661e-24	111.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,267CA@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_8050791_2	314262.MED193_07588	2.888e-36	147.0	COG5395@1|root,COG5395@2|Bacteria,1REYE@1224|Proteobacteria,2UB3Q@28211|Alphaproteobacteria,2P41W@2433|Roseobacter	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
GDHHQS3_k127_8050791_3	1382306.JNIM01000001_gene1359	5.081e-25	115.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
GDHHQS3_k127_8050791_1	1207075.PputUW4_02899	1.542e-63	223.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,1S25M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GDHHQS3_k127_8050791_0	1410665.JNKR01000003_gene1988	2.771e-72	252.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H274@909932|Negativicutes	909932|Negativicutes	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_8059120_1	330214.NIDE2632	1.319e-21	98.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS3_k127_8059120_0	32057.KB217478_gene3148	1.711e-45	166.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS3_k127_8059120_3	588581.Cpap_4023	5.274e-07	57.0	2AA7Z@1|root,30ZH6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4238
GDHHQS3_k127_8059120_2	331869.BAL199_13718	1.343e-10	71.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_8064366_2	941449.dsx2_1557	4.51e-10	67.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2M8I2@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS3_k127_8064366_0	479434.Sthe_1991	6.929e-98	343.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi,27XZD@189775|Thermomicrobia	189775|Thermomicrobia	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_8064366_1	1410624.JNKK01000002_gene957	1.832e-28	129.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,27J9M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS3_k127_8067474_5	1121335.Clst_2110	1.06e-27	126.0	COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,TPR_12,TPR_8
GDHHQS3_k127_8067474_0	1238182.C882_0318	1.257e-169	541.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria,2JPMR@204441|Rhodospirillales	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ccrA	-	1.1.1.1,1.3.1.85	ko:K00001,ko:K14446	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_8067474_6	1392491.JIAE01000001_gene1608	1.038e-17	91.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WI5H@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
GDHHQS3_k127_8067474_1	309801.trd_A0851	4.1e-87	312.0	COG0154@1|root,COG0154@2|Bacteria,2G84N@200795|Chloroflexi,27XQZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GDHHQS3_k127_8067474_3	216591.BCAM1965	1.895e-41	161.0	COG0546@1|root,COG0546@2|Bacteria,1N2ZG@1224|Proteobacteria,2WFH1@28216|Betaproteobacteria,1KFYR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_8067474_4	1123257.AUFV01000014_gene3369	6.297e-35	138.0	COG1765@1|root,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1RMZV@1236|Gammaproteobacteria,1X802@135614|Xanthomonadales	135614|Xanthomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS3_k127_8067474_2	326427.Cagg_1130	1.886e-53	202.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_8070290_4	97096.XP_007796553.1	4.787e-28	118.0	COG1546@1|root,2S20M@2759|Eukaryota,3A3UF@33154|Opisthokonta,3P4XD@4751|Fungi,3QX2B@4890|Ascomycota	4751|Fungi	S	Competence-damaged protein	-	-	-	-	-	-	-	-	-	-	-	-	CinA
GDHHQS3_k127_8070290_2	1123023.JIAI01000002_gene4864	5.047e-39	159.0	COG1052@1|root,COG1052@2|Bacteria,2I2IC@201174|Actinobacteria,4E50T@85010|Pseudonocardiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA3	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_8070290_0	1007105.PT7_3292	6.649e-41	157.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VS89@28216|Betaproteobacteria,3T3PQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alkylhydroperoxidase AhpD family core domain-containing protein 7	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_8070290_3	1382306.JNIM01000001_gene3443	2.962e-29	120.0	COG0023@1|root,COG0023@2|Bacteria,2G9JW@200795|Chloroflexi	200795|Chloroflexi	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GDHHQS3_k127_8070290_1	1120934.KB894404_gene667	1.279e-40	162.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4DXF8@85010|Pseudonocardiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
GDHHQS3_k127_8070290_5	886377.Murru_0443	2.717e-11	66.0	2AF0Z@1|root,314Z9@2|Bacteria,4P7CF@976|Bacteroidetes,1IAXW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8070290_6	316274.Haur_4578	8.911e-06	52.0	COG1277@1|root,COG1277@2|Bacteria,2GB1V@200795|Chloroflexi,377RP@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GDHHQS3_k127_8076021_4	1463857.JOFZ01000005_gene3355	1.118e-22	103.0	2DWN2@1|root,3414B@2|Bacteria,2IC7M@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_8076021_3	926561.KB900620_gene2912	3.705e-28	131.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS3_k127_8076021_1	1166018.FAES_3360	3.532e-70	250.0	COG0604@1|root,COG0604@2|Bacteria,4NPBM@976|Bacteroidetes,47Q08@768503|Cytophagia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_8076021_0	1123023.JIAI01000018_gene2512	1.96e-82	286.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.16	ko:K05713	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R04376,R06788	RC01140,RC01364	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
GDHHQS3_k127_8076021_2	1509405.GV67_12360	2.384e-49	186.0	2ADB9@1|root,3130Q@2|Bacteria,1PRK3@1224|Proteobacteria,2V3V6@28211|Alphaproteobacteria,4BINX@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS3_k127_808624_1	1211815.CBYP010000014_gene3514	5.63e-07	61.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
GDHHQS3_k127_808624_0	479434.Sthe_3245	4.146e-200	643.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	2|Bacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
GDHHQS3_k127_8093651_0	251221.35210613	1.156e-66	245.0	COG0596@1|root,COG4188@1|root,COG0596@2|Bacteria,COG4188@2|Bacteria,1G7IV@1117|Cyanobacteria	1117|Cyanobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS3_k127_8097413_0	663610.JQKO01000002_gene1225	6.545e-13	78.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,3NA8W@45404|Beijerinckiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_8097413_1	1206743.BAGM01000008_gene3760	3.883e-05	50.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4FUY7@85025|Nocardiaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_8101669_0	479434.Sthe_0347	2.511e-69	246.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,27XF2@189775|Thermomicrobia	189775|Thermomicrobia	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS3_k127_8101669_1	1306990.BARG01000086_gene8532	4.831e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,2I94W@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_8101669_2	1210884.HG799473_gene14950	7.137e-31	128.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS3_k127_8110700_1	926569.ANT_19690	3.5e-19	90.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_8110700_0	1118054.CAGW01000024_gene451	3.123e-106	355.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M20	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_813265_0	243164.DET1464	0.0	1043.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,34CSK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_818039_0	38833.XP_003059695.1	2.107e-39	154.0	COG0769@1|root,2QTHZ@2759|Eukaryota,37ICR@33090|Viridiplantae,34HMZ@3041|Chlorophyta	3041|Chlorophyta	J	Mur ligase family, glutamate ligase domain	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_8203389_3	552811.Dehly_0237	1.292e-31	128.0	COG0761@1|root,COG0761@2|Bacteria,2G75Z@200795|Chloroflexi,34CJU@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GDHHQS3_k127_8203389_2	485913.Krac_8546	1.191e-37	151.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_8203389_1	373903.Hore_10390	4.352e-52	192.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WAMU@53433|Halanaerobiales	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS3_k127_8203389_0	255470.cbdbA741	5.177e-53	194.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
GDHHQS3_k127_8226150_3	399795.CtesDRAFT_PD2927	5.677e-49	182.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,4AJ77@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_8226150_2	768706.Desor_3116	8.208e-52	189.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,26208@186807|Peptococcaceae	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.17.1.5,1.2.5.3	ko:K03518,ko:K13483,ko:K20446	ko00230,ko00760,ko01100,ko01120,map00230,map00760,map01100,map01120	M00546	R01720,R01768,R02103,R11168	RC00143,RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_8226150_4	204669.Acid345_2647	2.2e-45	175.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria,2JP44@204432|Acidobacteriia	204432|Acidobacteriia	C	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS3_k127_8226150_0	525904.Tter_0396	2.844e-67	239.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_8226150_5	1123023.JIAI01000002_gene4891	1.886e-35	138.0	COG1733@1|root,COG1733@2|Bacteria,2HEVV@201174|Actinobacteria,4ED15@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GDHHQS3_k127_8226150_1	1173028.ANKO01000170_gene3361	1.131e-52	190.0	COG0346@1|root,COG0346@2|Bacteria,1GAIM@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_8226150_6	1172179.AUKV01000005_gene5982	1.37e-26	112.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GDHHQS3_k127_8244955_0	1278073.MYSTI_04661	1.844e-72	259.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_8244955_1	1459636.NTE_02658	7.1e-20	94.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	hadL	-	3.1.3.18,3.8.1.2,3.8.1.3	ko:K01091,ko:K01560,ko:K01561,ko:K07025	ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130	-	R01334,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
GDHHQS3_k127_8266685_1	465541.ATCJ01000005_gene738	1.216e-65	237.0	COG0438@1|root,COG0438@2|Bacteria,2GR58@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8266685_2	649638.Trad_2042	1.683e-56	211.0	COG0388@1|root,COG0388@2|Bacteria,1WJ47@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GDHHQS3_k127_8266685_3	555779.Dthio_PD3359	0.0001764	46.0	2CEZQ@1|root,33C4G@2|Bacteria,1P9ED@1224|Proteobacteria,432EU@68525|delta/epsilon subdivisions,2WYJ9@28221|Deltaproteobacteria,2MFPC@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8266685_0	1380394.JADL01000002_gene1605	2.113e-118	386.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria,2TSMG@28211|Alphaproteobacteria,2JQ2V@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_8293585_3	1463825.JNXC01000001_gene6059	2.845e-31	132.0	COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria,4E2PC@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_8293585_0	1134413.ANNK01000127_gene2532	2.305e-87	303.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_8293585_2	1122915.AUGY01000020_gene6474	6.211e-32	134.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.1.69,4.1.2.17	ko:K01628,ko:K18256	ko00051,ko00624,ko01120,map00051,map00624,map01120	M00636	R01634,R02262	RC00569,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,UPF0066
GDHHQS3_k127_8293585_5	1121017.AUFG01000004_gene3261	0.0004132	44.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria,4FGUM@85021|Intrasporangiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_8293585_1	255470.cbdbA1358	1.729e-55	198.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,34D7Q@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_8348219_3	1521187.JPIM01000042_gene1868	6.076e-10	68.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,376MF@32061|Chloroflexia	32061|Chloroflexia	F	PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_8348219_1	326427.Cagg_3362	2.926e-65	228.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GDHHQS3_k127_8348219_2	1122182.KB903814_gene3569	3.541e-17	84.0	2CA4F@1|root,33DCB@2|Bacteria,2GRQ2@201174|Actinobacteria,4DG72@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8348219_0	485913.Krac_7682	2.636e-140	451.0	COG0112@1|root,COG0112@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	SHMT
GDHHQS3_k127_8366600_2	1128421.JAGA01000002_gene1668	3.625e-27	116.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	2.4.2.21,5.4.2.12	ko:K00768,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04148	RC00033,RC00063,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
GDHHQS3_k127_8366600_1	1324957.K933_06753	3.221e-31	132.0	COG0494@1|root,arCOG01072@2157|Archaea,2XWJS@28890|Euryarchaeota,23VF0@183963|Halobacteria	183963|Halobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_8366600_0	926569.ANT_17720	3.625e-140	458.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS3_k127_8402536_2	1210884.HG799465_gene11655	4.906e-42	158.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
GDHHQS3_k127_8402536_0	243164.DET0742	2.161e-71	253.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,34CU5@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS3_k127_8402536_1	1521187.JPIM01000139_gene2215	1.788e-63	225.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS3_k127_8407279_0	234267.Acid_3133	1.322e-82	297.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,PD40,TPR_10,TPR_12,TPR_8
GDHHQS3_k127_8414041_2	889378.Spiaf_0220	2.086e-15	83.0	292V4@1|root,2ZQCQ@2|Bacteria,2J8H2@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8414041_3	1047013.AQSP01000144_gene811	8.543e-12	77.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
GDHHQS3_k127_8414041_1	1229780.BN381_750002	1.764e-29	122.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8414041_0	573413.Spirs_3713	1.524e-53	190.0	COG0449@1|root,COG0449@2|Bacteria,2J587@203691|Spirochaetes	203691|Spirochaetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS3_k127_8414572_1	1089553.Tph_c20870	4.255e-08	55.0	COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JG8@68295|Thermoanaerobacterales	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_9,SBP_bac_3
GDHHQS3_k127_8414572_0	1122611.KB903948_gene6718	9.287e-27	126.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
GDHHQS3_k127_8427441_0	649831.L083_4492	2.886e-69	250.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4D9QK@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8427441_1	1306174.JODP01000020_gene360	4.455e-28	116.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_8445273_2	656024.FsymDg_0267	6.332e-08	62.0	COG1960@1|root,COG1960@2|Bacteria,2GKYY@201174|Actinobacteria,4EW2Z@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8445273_1	314231.FP2506_07301	3.593e-10	64.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_8445273_0	888059.HMPREF9071_0945	2.231e-39	147.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia,1EQSZ@1016|Capnocytophaga	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS3_k127_8448707_0	552811.Dehly_1128	9.912e-64	229.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi,34CMT@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_8448707_2	429009.Adeg_0147	1.305e-34	144.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,42GXN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0079, ATPase	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GDHHQS3_k127_8448707_1	255470.cbdbA344	1.281e-35	145.0	COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Glycoprotease family	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Peptidase_M22
GDHHQS3_k127_8448707_3	309801.trd_1770	1.82e-33	130.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi,27Y9T@189775|Thermomicrobia	189775|Thermomicrobia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS3_k127_8495395_0	326427.Cagg_2527	2.649e-161	522.0	COG0318@1|root,COG0318@2|Bacteria,2G83V@200795|Chloroflexi,376U1@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_8495395_8	1121935.AQXX01000105_gene345	1.021e-15	87.0	2CKF9@1|root,348E8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8495395_7	1089551.KE386572_gene396	1.743e-37	152.0	COG1560@1|root,COG1560@2|Bacteria,1NJIN@1224|Proteobacteria	1224|Proteobacteria	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_8495395_2	1040989.AWZU01000006_gene456	2.322e-104	355.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,3JYAZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	nah	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
GDHHQS3_k127_8495395_4	1144310.PMI07_005437	1.769e-59	214.0	COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria,4BJMH@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
GDHHQS3_k127_8495395_1	35754.JNYJ01000086_gene2289	3.091e-105	348.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4DCWY@85008|Micromonosporales	201174|Actinobacteria	S	Aldo/keto reductase family	dkgA	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
GDHHQS3_k127_8495395_5	1254432.SCE1572_24685	2.962e-44	180.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GDHHQS3_k127_8495395_3	1133849.O3I_027875	5.761e-60	219.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GDHHQS3_k127_8495395_9	644284.Arch_0579	1.736e-05	53.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4D409@85005|Actinomycetales	201174|Actinobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_8495395_6	331869.BAL199_08898	5.739e-44	176.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8516212_0	479434.Sthe_2199	1.095e-236	752.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GDHHQS3_k127_8516212_3	1122138.AQUZ01000036_gene5424	9.023e-07	61.0	28MGS@1|root,2ZATX@2|Bacteria,2I6PR@201174|Actinobacteria,4DNKC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS3_k127_8516212_2	1034347.CAHJ01000077_gene1256	1.602e-34	147.0	COG2807@1|root,COG2807@2|Bacteria,1UJ09@1239|Firmicutes,4ISZA@91061|Bacilli,1ZSFH@1386|Bacillus	91061|Bacilli	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8529205_0	311424.DhcVS_300	1.215e-126	422.0	28MN1@1|root,2ZAXN@2|Bacteria,2G6CU@200795|Chloroflexi,34D42@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8529205_1	243164.DET0358	6.751e-09	61.0	2BQ9G@1|root,32J4A@2|Bacteria,2GAU8@200795|Chloroflexi,34DCZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_852923_1	1380346.JNIH01000006_gene3549	9.857e-06	58.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
GDHHQS3_k127_852923_0	479434.Sthe_1819	4.582e-21	96.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS3_k127_8551240_2	1304877.KI519399_gene2078	4.891e-27	118.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3JR0X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_8551240_3	1382356.JQMP01000004_gene207	2.009e-23	104.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GDHHQS3_k127_8551240_0	525904.Tter_0082	5.996e-121	403.0	COG1232@1|root,COG1232@2|Bacteria,2NQRF@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS3_k127_8551240_1	316274.Haur_2793	8.877e-53	198.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_8559277_1	1121468.AUBR01000017_gene2371	2.212e-110	364.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS3_k127_8559277_5	552811.Dehly_1038	6.847e-26	111.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,34DF5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS3_k127_8559277_3	926550.CLDAP_15340	3.242e-71	249.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_8559277_0	926550.CLDAP_15350	1.309e-142	486.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
GDHHQS3_k127_8559277_2	1288826.MSNKSG1_15581	6.844e-87	304.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
GDHHQS3_k127_8559277_4	926569.ANT_30540	5.686e-51	198.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8562372_0	909613.UO65_1053	1.651e-126	409.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DXA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GDHHQS3_k127_8562372_1	1231391.AMZF01000110_gene916	6.474e-88	297.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_8645969_3	985665.HPL003_26480	7.929e-05	53.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_8645969_0	1385514.N782_01025	6.11e-71	251.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,2Y92T@289201|Pontibacillus	91061|Bacilli	U	Transports peptides consisting of two or three amino acids	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_8645969_1	469383.Cwoe_0132	1.304e-47	183.0	COG1173@1|root,COG1173@2|Bacteria,2HF47@201174|Actinobacteria,4CSSR@84995|Rubrobacteria	84995|Rubrobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_8645969_2	1120972.AUMH01000002_gene2760	2.59e-21	97.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_8646715_1	118005.AWNK01000008_gene424	2.035e-123	413.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_8646715_0	552811.Dehly_0839	6.678e-171	559.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,34D55@301297|Dehalococcoidia	301297|Dehalococcoidia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_8646715_4	197221.22294391	1.553e-25	109.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
GDHHQS3_k127_8646715_3	1121472.AQWN01000005_gene2478	2.547e-26	117.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,2626F@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_8646715_2	255470.cbdbA879	1.476e-89	310.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi,34CTC@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_8646715_5	794903.OPIT5_21980	1.569e-05	47.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_8647394_0	871968.DESME_13520	7.605e-180	585.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,249N1@186801|Clostridia,260S4@186807|Peptococcaceae	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_8647394_1	926569.ANT_30630	4.002e-86	294.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
GDHHQS3_k127_8647394_2	1231391.AMZF01000069_gene2124	9.318e-28	119.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8651200_0	909663.KI867150_gene271	1.782e-131	432.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2MQNQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
GDHHQS3_k127_8651200_2	497321.C664_02445	0.0001475	44.0	COG0589@1|root,COG3945@1|root,COG0589@2|Bacteria,COG3945@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQ5J@28216|Betaproteobacteria,2KYX9@206389|Rhodocyclales	206389|Rhodocyclales	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Usp
GDHHQS3_k127_8651200_1	1380394.JADL01000001_gene2346	2.735e-15	78.0	COG1028@1|root,COG1028@2|Bacteria,1QWBB@1224|Proteobacteria,2U2FD@28211|Alphaproteobacteria,2JVVT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_8655093_0	383372.Rcas_1032	9.434e-143	467.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi,376DU@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS3_k127_8655093_1	1356854.N007_08195	1.726e-74	260.0	COG2267@1|root,COG2267@2|Bacteria,1UHRJ@1239|Firmicutes,4IS7F@91061|Bacilli,27AT4@186823|Alicyclobacillaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_8655093_2	1214101.BN159_1370	3.132e-59	217.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	MA20_13990	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	Lactamase_B
GDHHQS3_k127_8687309_5	338966.Ppro_3233	2.877e-12	80.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GDHHQS3_k127_8687309_3	1303518.CCALI_01463	1.116e-79	273.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8687309_1	1382356.JQMP01000003_gene1449	3.992e-111	381.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8687309_0	644966.Tmar_0496	4.384e-129	431.0	2DNJB@1|root,32XT8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8687309_2	316274.Haur_1720	1.182e-94	327.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi,37556@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_8687309_4	266117.Rxyl_1174	4.677e-42	158.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS3_k127_8708486_0	765420.OSCT_1058	9.987e-114	374.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_8708486_1	1120949.KB903356_gene8475	5.086e-51	192.0	COG0637@1|root,COG0637@2|Bacteria,2I76G@201174|Actinobacteria	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_8727068_0	1121440.AUMA01000007_gene1048	2.044e-45	179.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2M927@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_8735765_2	1379698.RBG1_1C00001G0735	7.711e-83	279.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS3_k127_8735765_6	467200.ACFA01000695_gene5378	2.308e-20	99.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
GDHHQS3_k127_8735765_9	1118054.CAGW01000062_gene2252	1.196e-05	50.0	COG0695@1|root,COG0775@1|root,COG0695@2|Bacteria,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,26TU4@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_8735765_10	358681.BBR47_13510	4.824e-05	51.0	COG0695@1|root,COG0695@2|Bacteria,1VGHM@1239|Firmicutes,4HQ0H@91061|Bacilli,26YY5@186822|Paenibacillaceae	91061|Bacilli	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GDHHQS3_k127_8735765_1	404589.Anae109_1187	2.559e-92	314.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2WN7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
GDHHQS3_k127_8735765_7	768710.DesyoDRAFT_0907	1.473e-11	74.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,26256@186807|Peptococcaceae	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS3_k127_8735765_0	429009.Adeg_0960	7.975e-114	381.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_8735765_4	264732.Moth_1000	7.761e-51	196.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_8735765_8	1172180.KB911793_gene3576	9.389e-11	66.0	COG0633@1|root,COG0633@2|Bacteria,2GSER@201174|Actinobacteria	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
GDHHQS3_k127_8735765_3	292459.STH241	2.211e-67	240.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS3_k127_8735765_5	390989.JOEG01000021_gene2674	4.086e-24	105.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4D9Q4@85008|Micromonosporales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS3_k127_8735846_0	479434.Sthe_3489	2.213e-96	332.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi	2|Bacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase,FCD
GDHHQS3_k127_8740891_2	365044.Pnap_3246	4.791e-54	198.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_8740891_0	1121272.KB903249_gene1588	1.684e-139	451.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DCFG@85008|Micromonosporales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_8740891_3	1458275.AZ34_14925	2.304e-50	188.0	COG0265@1|root,COG0265@2|Bacteria,1QWA4@1224|Proteobacteria,2VK6X@28216|Betaproteobacteria,4A9X2@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
GDHHQS3_k127_8740891_5	330214.NIDE3802	4.173e-19	92.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,GGDEF
GDHHQS3_k127_8740891_6	1121124.JNIX01000008_gene2586	8.84e-10	66.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,2UFXH@28211|Alphaproteobacteria,2KJM2@204458|Caulobacterales	204458|Caulobacterales	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
GDHHQS3_k127_8740891_1	485913.Krac_10271	5.937e-56	204.0	COG0500@1|root,COG2226@2|Bacteria,2GA94@200795|Chloroflexi	200795|Chloroflexi	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_8740891_4	521674.Plim_1577	2.616e-23	107.0	COG1028@1|root,COG1028@2|Bacteria,2IXK3@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_875328_5	1177154.Y5S_03462	4.16e-99	340.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
GDHHQS3_k127_875328_14	1122201.AUAZ01000002_gene1051	0.0003055	52.0	COG2199@1|root,COG2199@2|Bacteria,1R922@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
GDHHQS3_k127_875328_13	29176.XP_003885647.1	0.0002749	50.0	2FCEU@1|root,2TDPF@2759|Eukaryota,3YCAG@5794|Apicomplexa,3YNJ9@5796|Coccidia,3YTFH@5809|Sarcocystidae	5794|Apicomplexa	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_8
GDHHQS3_k127_875328_11	161156.JQKW01000006_gene1143	1.652e-09	62.0	COG1522@1|root,COG1522@2|Bacteria,2GI4U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS3_k127_875328_10	1353529.M899_1988	9.077e-10	66.0	COG0517@1|root,COG0517@2|Bacteria,1QAJW@1224|Proteobacteria,42XWB@68525|delta/epsilon subdivisions,2WTBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_875328_0	351607.Acel_0284	5.532e-237	749.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4ERWB@85013|Frankiales	201174|Actinobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS3_k127_875328_1	530564.Psta_0806	2.087e-142	459.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS3_k127_875328_9	109760.SPPG_06279T0	8.317e-12	72.0	COG0517@1|root,2QVK2@2759|Eukaryota,39AEJ@33154|Opisthokonta,3NVCH@4751|Fungi	4751|Fungi	P	CBS and PB1 domain protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0012505,GO:0016020,GO:0031090,GO:0031965,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464	-	-	-	-	-	-	-	-	-	-	CBS,PB1
GDHHQS3_k127_875328_3	671143.DAMO_1215	2.654e-104	347.0	COG0524@1|root,COG0524@2|Bacteria,2NP1T@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
GDHHQS3_k127_875328_8	253839.SSNG_06162	4.09e-20	95.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS3_k127_875328_7	357808.RoseRS_0656	1.042e-37	159.0	COG3021@1|root,COG3021@2|Bacteria,2G9DW@200795|Chloroflexi,377KI@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS3_k127_875328_6	448385.sce7198	1.436e-61	225.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_875328_4	671143.DAMO_3064	1.118e-99	338.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_875328_12	1357272.AVEO02000026_gene3157	2.395e-09	68.0	COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,1T1MX@1236|Gammaproteobacteria,1Z52V@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	C	Oxidoreductase FAD-binding domain	fpr	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
GDHHQS3_k127_875328_2	278963.ATWD01000001_gene3182	3.185e-125	410.0	COG1793@1|root,COG1793@2|Bacteria,3Y45N@57723|Acidobacteria,2JIH0@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
GDHHQS3_k127_8852603_3	522306.CAP2UW1_2635	1.136e-14	79.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria	28216|Betaproteobacteria	I	dehydrogenase	tsaR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_8852603_1	864051.BurJ1DRAFT_2440	4.063e-74	263.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VN7W@28216|Betaproteobacteria,1KIZJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
GDHHQS3_k127_8852603_2	316274.Haur_3823	2.786e-65	232.0	COG0566@1|root,COG0566@2|Bacteria,2G7XK@200795|Chloroflexi,376BA@32061|Chloroflexia	32061|Chloroflexia	H	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
GDHHQS3_k127_8852603_0	1381123.AYOD01000060_gene1649	6.426e-81	280.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,43IAS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GDHHQS3_k127_8863185_1	1001585.MDS_1415	1.996e-46	176.0	COG4122@1|root,COG4122@2|Bacteria,1PDQU@1224|Proteobacteria,1TCHR@1236|Gammaproteobacteria,1YKCF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
GDHHQS3_k127_8863185_0	661478.OP10G_3277	3.54e-73	257.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_8903831_5	309801.trd_1644	3.35e-39	150.0	2DBIJ@1|root,2Z9G2@2|Bacteria,2G896@200795|Chloroflexi,27XN4@189775|Thermomicrobia	189775|Thermomicrobia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
GDHHQS3_k127_8903831_3	1218084.BBJK01000013_gene1424	8.619e-69	246.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2VMW1@28216|Betaproteobacteria,1K1I4@119060|Burkholderiaceae	28216|Betaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
GDHHQS3_k127_8903831_7	935866.JAER01000039_gene597	4.3e-05	53.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_8903831_4	1382356.JQMP01000003_gene2062	8.33e-45	179.0	COG2223@1|root,COG2223@2|Bacteria,2GBND@200795|Chloroflexi,27XPQ@189775|Thermomicrobia	189775|Thermomicrobia	P	PUCC protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8903831_6	67352.JODS01000023_gene3417	2.555e-19	98.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
GDHHQS3_k127_8903831_0	1242864.D187_007727	7.872e-242	754.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YU8Q@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS3_k127_8903831_1	1128421.JAGA01000002_gene898	6.392e-186	588.0	COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS3_k127_8903831_2	383372.Rcas_3282	6.72e-73	259.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GDHHQS3_k127_8936951_3	338963.Pcar_0765	4.07e-63	230.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,43B63@68525|delta/epsilon subdivisions,2X6JM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_8936951_0	1173028.ANKO01000020_gene5535	3.773e-132	437.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HH6G@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_8936951_8	411474.COPEUT_00969	2.229e-09	61.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_8936951_2	1206731.BAGB01000164_gene4295	2e-66	239.0	COG3384@1|root,COG3384@2|Bacteria,2IAUK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B	-	-	-	-	-	-	-	-	-	-	-	-	LigB
GDHHQS3_k127_8936951_9	1094508.Tsac_0780	3.784e-09	67.0	COG2197@1|root,COG2197@2|Bacteria,1TW4Y@1239|Firmicutes,25B3S@186801|Clostridia	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_8936951_10	485913.Krac_0928	1.949e-08	63.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_0928|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8936951_11	446468.Ndas_3419	4.439e-07	56.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4EKF4@85012|Streptosporangiales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_8936951_7	1158606.I579_02394	1.399e-18	92.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,4B2PX@81852|Enterococcaceae	91061|Bacilli	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS3_k127_8936951_4	565033.GACE_2148	2.263e-46	176.0	COG0428@1|root,arCOG00576@2157|Archaea,2XXNC@28890|Euryarchaeota,246ZF@183980|Archaeoglobi	183980|Archaeoglobi	P	PFAM zinc iron permease	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
GDHHQS3_k127_8936951_5	1009370.ALO_10609	7.279e-40	160.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4H4P0@909932|Negativicutes	909932|Negativicutes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
GDHHQS3_k127_8936951_1	1408254.T458_04785	6.651e-77	268.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS3_k127_8936951_6	1121472.AQWN01000003_gene1440	5.194e-21	96.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,2602S@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
GDHHQS3_k127_8948663_2	760011.Spico_0624	5.787e-18	86.0	COG0488@1|root,COG0488@2|Bacteria,2J5P1@203691|Spirochaetes	203691|Spirochaetes	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_8948663_1	1227349.C170_11605	3.802e-25	106.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,26ZRV@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
GDHHQS3_k127_8948663_0	595494.Tola_1754	2.194e-89	304.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1Y61V@135624|Aeromonadales	135624|Aeromonadales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_8951087_1	311424.DhcVS_617	3.867e-77	264.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,34D07@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS3_k127_8951087_6	293826.Amet_1729	0.0005502	47.0	COG3311@1|root,COG3311@2|Bacteria,1VEEK@1239|Firmicutes,24TTF@186801|Clostridia	1239|Firmicutes	L	TIGRFAM DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_8951087_5	926569.ANT_19700	1.279e-22	105.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_8951087_4	552811.Dehly_1711	7.847e-45	170.0	COG1211@1|root,COG1211@2|Bacteria,2G6UP@200795|Chloroflexi,34D6D@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
GDHHQS3_k127_8951087_3	309801.trd_1723	4.544e-45	168.0	COG0245@1|root,COG0245@2|Bacteria,2G6RA@200795|Chloroflexi,27YBC@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GDHHQS3_k127_8951087_2	935948.KE386495_gene1534	1.788e-62	224.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,42ENY@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
GDHHQS3_k127_8951087_0	485916.Dtox_0265	6.195e-107	354.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS3_k127_950852_3	1122963.AUHB01000002_gene762	0.0001422	45.0	COG3794@1|root,COG3794@2|Bacteria,1MZWU@1224|Proteobacteria,2UC7P@28211|Alphaproteobacteria,36YNZ@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Copper-bind
GDHHQS3_k127_950852_2	443598.AUFA01000032_gene6458	4.807e-06	51.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JR1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS3_k127_950852_0	1038860.AXAP01000019_gene2615	7.286e-43	163.0	COG0251@1|root,COG0251@2|Bacteria,1R7PF@1224|Proteobacteria,2U41B@28211|Alphaproteobacteria,3JW5Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_950852_1	1144310.PMI07_001566	5.131e-28	113.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,4B9SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GDHHQS3_k127_952948_0	1442599.JAAN01000005_gene979	9.844e-132	428.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1X45W@135614|Xanthomonadales	135614|Xanthomonadales	S	4-oxalomesaconate hydratase	fldW	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
GDHHQS3_k127_952948_1	1144310.PMI07_001945	4.425e-121	394.0	COG3836@1|root,COG3836@2|Bacteria,1R9U6@1224|Proteobacteria,2TSTY@28211|Alphaproteobacteria,4B7QE@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
## 1965 queries scanned
## Total time (seconds): 229.73877549171448
## Rate: 8.55 q/s